Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health – Details, episodes & analysis
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Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health
Joanne Kennedy
Frequency: 1 episode/8d. Total Eps: 61

The Histamine Well is a podcast for health practitioners and patients alike, bridging the gap between complex science and practical understanding. With a focus on histamine, methylation, and related health topics, the show translates advanced concepts into actionable insights for practitioners while empowering patients with accessible, evidence-based knowledge.
Your host, Joanne Kennedy, is a naturopath and expert in histamine intolerance, MTHFR, and methylation. She is also an author and runs an online group coaching program for practitioners and students on histamine and methylation. Jo loves breaking down complex science into clear, easy-to-understand language, offering practical tips and the latest insights to empower you to take charge of your health.
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31. How to Protect Your Home from Mold and EMF Exposure with Building Biologist Jo Lia
Episode 31
lundi 10 novembre 2025 • Duration 01:01:06
Is your home secretly affecting your health? In this episode of The Histamine Well Podcast, Joanne’s colleague Melanie Peers sits down with Building Biologist Jo Lia to uncover the hidden dangers of mold, electromagnetic fields (EMF), and poor indoor air quality.
Jo shares her journey into building biology and explains how unseen environmental factors—like hidden mold spores or constant EMF exposure—can impact your immune system, mood, and energy levels. Together, they break down what you can do to make your home a truly healthy space, from proper mold testing and remediation to simple steps that minimize EMF radiation in your daily life.
If you’ve struggled with chronic inflammation, fatigue, allergies, or unexplained symptoms, this episode will help you connect the dots between your home environment and your health.
What You’ll Learn:
- How to identify the early signs of mold in your home
- The truth about EMFs and how they affect your health
- Simple ways to reduce EMF exposure from Wi-Fi and devices
- What to do if you suspect mold contamination — and how to remediate safely
- Why modern airtight homes can worsen indoor air quality
- How to improve ventilation and maintain clean indoor air
- How to find and work with a certified Building Biologist
- Practical tips for creating a toxin-free, health-supportive living environment
Connect with Jo Lia:
🌿 Website: https://www.notoxrox.com/
📸 Instagram: @notoxrox
📘 Facebook: facebook.com/notoxrox
Australian Society of Building Biologists: https://www.asbb.org.au/
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
30. Hydrogen Sulfide SIBO Explained: Symptoms, Testing & Treatments with Rosaria Nithart
Episode 30
lundi 27 octobre 2025 • Duration 39:02
In this episode of The Histamine Well Podcast, Joanne sits down with Rosaria Nithart, a French-based naturopath specializing in digestive health, to uncover the complexities of Hydrogen Sulfide SIBO—one of the most misunderstood forms of Small Intestinal Bacterial Overgrowth (SIBO).
Together, they break down how Hydrogen Sulfide SIBO differs from hydrogen- and methane-dominant SIBO, exploring the unique bacteria and biochemical pathways involved. Rosaria shares her step-by-step naturopathic framework for identifying, testing, and treating Hydrogen Sulfide SIBO naturally. The conversation also dives deep into the role of sulfur metabolism, oxalates, and molybdenum in managing symptoms and restoring gut balance.
Listeners will learn:
- The root causes and drivers behind Hydrogen Sulfide SIBO
- How to identify key symptoms and understand testing limitations
- The connection between sulfur, oxalates, and bacterial imbalances
- Practical treatment strategies that support gut healing without extreme diets
- How Hydrogen Sulfide SIBO links to UTIs, histamine intolerance, and detox pathways
Whether you’re a practitioner seeking deeper clinical insights or a patient navigating chronic gut issues, this episode offers a clear, actionable approach to understanding and managing Hydrogen Sulfide SIBO naturally.
Connect with Rosaria Nithart:
- Website: rosarianithart.com | rosarianithart.it
- Facebook: facebook.com/rosaria.nithart
- Instagram: @rosarianithartnaturopathe
Breath Tests for Hydrogen, Methane & Hydrogen Sulfide:
- Trio Smart (USA / Canada)– Trio-Smart® — The only 3-Gas SIBO Breath Test: https://www.triosmartbreath.com/
- Nordic Labs (Europe) – https://nordiclabs.com/EProduct.aspx
- Invivo Healthcare (UK): https://invivohealthcare.com/
- Teletest (Spain): https://www.teletest.es/ | https://www.facebook.com/teletest/
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
21. How to Treat SIBO Naturally: Diet, Herbs, Testing & the Clinical Approach That Works
Episode 21
lundi 21 juillet 2025 • Duration 33:13
Struggling with persistent SIBO symptoms or unsure where to start with natural treatment? In this episode, I break down exactly how I treat SIBO in clinic — from diet and herbs to overlooked factors like biofilm, enzymes, histamine, and oxalates.
Whether you're a health practitioner, student, or someone personally dealing with SIBO, you'll walk away with a deep understanding of the step-by-step process required for real, lasting results — not just temporary relief.
What I Cover:
✔️ Why a low FODMAP diet is non-negotiable if you're treating SIBO naturally
✔️ How to use testing — and retesting — to guide effective treatment
✔️ The best herbs for hydrogen and methane SIBO (and why they differ)
✔️ The role of SIFO (Small Intestinal Fungal Overgrowth) and how to spot it
✔️ Why addressing biofilm is essential for treatment success
✔️ How digestive enzymes (including brush border support) accelerate healing
✔️ The hidden role of histamine intolerance in stubborn cases
✔️ Why oxalates can spike on a low FODMAP diet — and what to do about it
✔️ What to do when the migrating motor complex (MMC) isn’t working
✔️ The best prokinetics, binders, and enzyme supplements I use in practice
✔️ When and how to safely reintroduce foods after treatment
✔️ What recurring SIBO is trying to tell you
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
20. Acid Load, Mineral Depletion & the Hidden Link to Histamine Intolerance & Oxalates
Episode 20
lundi 14 juillet 2025 • Duration 35:16
In this episode of The Histamine Well, we're diving into one of the most overlooked root causes behind symptoms like fatigue, histamine intolerance, hormonal imbalance, oxalate sensitivity, mood swings, and chronic inflammation: acid load and mineral depletion.
You'll learn:
- Where acidity in the body comes from — from diet and inflammation to mitochondrial dysfunction and gut dysbiosis
- How acid load disrupts key systems, including hormones, energy, detoxification, and neurotransmitters
- Why histamine and oxalates are inherently acidic — and how that ramps up symptoms in sensitive individuals
- The role of bicarbonate and minerals in buffering acid and maintaining systemic pH balance
- How to interpret functional blood markers like bicarbonate and the anion gap (and what they actually mean)
- Why simply adding more supplements won’t fix a stressed nervous system or mineral-depleted biochemistry
- Which alkalizing mineral formulas and mitochondrial supports Joanne recommends in clinical practice — including Basica, Orthoplex Alkamin, and ATP Fuel
Whether you're a practitioner, student, or someone deep in their own healing journey, this episode will shift how you view symptoms and recovery — especially if you’ve hit a wall despite ‘doing all the right things.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
19. Clinical Insights into PMDD, Severe PMS & the Role of Methylation
Episode 19
lundi 7 juillet 2025 • Duration 14:33
In this episode of The Histamine Well, Joanne dives deep into Premenstrual Dysphoric Disorder (PMDD) and severe PMS — the kind that can leave you feeling anxious, depressed, exhausted, and unlike yourself for half the month.
Joanne shares insights from her clinical practice to explore what’s really going on beneath the surface, including:
- Hormone imbalances like estrogen dominance and low progesterone
- Inflammation, oxidative stress, and their impact on ovulation
- Nutrient deficiencies that affect mood and hormone function
- The surprising role of methylation imbalances — particularly overmethylation — and how this biochemical pathway can disrupt neurotransmitters and mood
She also introduces the concept of testing methylation in real time, and shares a powerful patient story that shows how personalized treatment can dramatically improve mood and cycle symptoms.
Whether you’ve been diagnosed with PMDD or you just know your PMS isn’t normal, this episode offers a fresh perspective and hope for more stable cycles and moods.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
18. Balancing Methylation: A Game-Changer for Mental Health, Perimenopause & Menopause
Episode 18
lundi 30 juin 2025 • Duration 01:01:06
In this episode of The Histamine Well, host Joanne speaks with Amanda Bradshaw, co-founder of Mood Sense, to explore the critical role methylation plays in mood, mental health, and hormonal transitions like perimenopause. Joanne shares her clinical insights and surprising test results showing that some patients assumed to be under-methylators were actually over-methylating—changing the course of their treatment.
Amanda opens up about her personal health journey through perimenopause and how balancing her methylation significantly improved symptoms like mood swings and hot flushes. Together, they unpack how methylation imbalances can impact not just mental health, but also relationships, family dynamics, and even parenting—especially in neurodivergent households.
Listeners will also gain practical guidance on how the Mood Sense test works, and how diet, lifestyle, and targeted supplements can help restore balance and support emotional resilience.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
17. How Gluten Causes Immune Dysfunction, Chronic Inflammation and High Histamine
Episode 17
lundi 23 juin 2025 • Duration 24:57
In this episode, Joanne Kennedy discusses a comprehensive case study of a patient with various symptoms like abdominal pain, migraines, and joint pain who was incorrectly suspected of having mold and oxalate problems. The root cause turned out to be gluten intolerance.
Joanne explains the impact of gluten on the immune system, highlighting how it can cause significant inflammation and histamine issues. She differentiates between celiac disease, wheat allergy, and non-celiac gluten sensitivity, explaining their symptoms, testing methods, and impacts on histamine production.
Joanne also provides insights into diagnosing these conditions and emphasizes the importance of closely examining patients' diets before attributing symptoms to more complex conditions like mold or oxalate issues.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
16. Emotional Eating, Gut Health & Histamine: A Conversation with Amber Romaniuk
Episode 16
lundi 16 juin 2025 • Duration 44:48
In this episode of the Histamine Well Podcast, Joanne is joined by Amber Romanic, an expert in emotional eating, digestion, and hormonal health.
Amber shares her personal journey overcoming emotional eating and discusses how it impacts gut health and increases histamine levels.
They explore common emotional eating triggers, the role of high cortisol, and the pitfalls of extreme diets like intermittent fasting.
Amber offers practical tips on managing emotional eating, the importance of healing one's relationship with food, and why self-care and setting healthy boundaries are crucial.
Additionally, they touch on the unique challenges women face during different phases of their menstrual cycles and why maintaining a balanced approach is essential for overall well-being.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
15. The Connection Between High Histamine Levels and Hypoglycemia
Episode 15
lundi 9 juin 2025 • Duration 12:52
In this episode of the Histamine Well Podcast, Joanne explores the surprising link between high histamine levels and hypoglycemia.
She details how elevated histamine can disrupt blood sugar regulation through various mechanisms, including overstimulation of insulin production, suppression of glucagon, and cortisol dysregulation.
Joanne also offers practical advice on managing high histamine and blood sugar levels through diet, stress management, and lifestyle changes.
Tune in to learn more about identifying and addressing histamine-related blood sugar crashes.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!
14. Understanding SIBO and Histamine: An In-Depth Discussion with Joanne Kennedy & Melanie Peers
Episode 14
lundi 2 juin 2025 • Duration 01:01:31
In this episode of the Histamine Well Podcast, Joanne is joined by her colleague Melanie Peers to discuss the relationship between small intestinal bacterial overgrowth (SIBO) and histamine intolerance.
They explore the complexities of SIBO, its causes, symptoms, and its impact on histamine levels in the body. Joanne and Melanie also delve into related issues such as the role of the migrating motor complex, the influence of stress, dietary impacts, and the significance of mold, oxalates, and sulfur in exacerbating histamine symptoms.
Practical advice on diagnosis, dietary adjustments, and treatment options is provided, making this episode an invaluable resource for both practitioners and individuals seeking to manage their gut health and histamine-related conditions.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.
📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.
🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.
🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!
📆 Work with us 1:1! Book a consultation and take your first step to real healing.
🎤 Have a topic suggestion? Submit it here!









