Explore every episode of the podcast Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health
| Title | Pub. Date | Duration | |
|---|---|---|---|
| 31. How to Protect Your Home from Mold and EMF Exposure with Building Biologist Jo Lia | 10 Nov 2025 | 01:01:06 | |
Is your home secretly affecting your health? In this episode of The Histamine Well Podcast, Joanne’s colleague Melanie Peers sits down with Building Biologist Jo Lia to uncover the hidden dangers of mold, electromagnetic fields (EMF), and poor indoor air quality. Jo shares her journey into building biology and explains how unseen environmental factors—like hidden mold spores or constant EMF exposure—can impact your immune system, mood, and energy levels. Together, they break down what you can do to make your home a truly healthy space, from proper mold testing and remediation to simple steps that minimize EMF radiation in your daily life. If you’ve struggled with chronic inflammation, fatigue, allergies, or unexplained symptoms, this episode will help you connect the dots between your home environment and your health. What You’ll Learn:
🌿 Website: https://www.notoxrox.com/ Australian Society of Building Biologists: https://www.asbb.org.au/ ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 30. Hydrogen Sulfide SIBO Explained: Symptoms, Testing & Treatments with Rosaria Nithart | 27 Oct 2025 | 00:39:02 | |
In this episode of The Histamine Well Podcast, Joanne sits down with Rosaria Nithart, a French-based naturopath specializing in digestive health, to uncover the complexities of Hydrogen Sulfide SIBO—one of the most misunderstood forms of Small Intestinal Bacterial Overgrowth (SIBO). Together, they break down how Hydrogen Sulfide SIBO differs from hydrogen- and methane-dominant SIBO, exploring the unique bacteria and biochemical pathways involved. Rosaria shares her step-by-step naturopathic framework for identifying, testing, and treating Hydrogen Sulfide SIBO naturally. The conversation also dives deep into the role of sulfur metabolism, oxalates, and molybdenum in managing symptoms and restoring gut balance. Listeners will learn:
Whether you’re a practitioner seeking deeper clinical insights or a patient navigating chronic gut issues, this episode offers a clear, actionable approach to understanding and managing Hydrogen Sulfide SIBO naturally. Connect with Rosaria Nithart:
Breath Tests for Hydrogen, Methane & Hydrogen Sulfide:
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 21. How to Treat SIBO Naturally: Diet, Herbs, Testing & the Clinical Approach That Works | 21 Jul 2025 | 00:33:13 | |
Struggling with persistent SIBO symptoms or unsure where to start with natural treatment? In this episode, I break down exactly how I treat SIBO in clinic — from diet and herbs to overlooked factors like biofilm, enzymes, histamine, and oxalates. Whether you're a health practitioner, student, or someone personally dealing with SIBO, you'll walk away with a deep understanding of the step-by-step process required for real, lasting results — not just temporary relief. What I Cover: ✔️ Why a low FODMAP diet is non-negotiable if you're treating SIBO naturally ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 20. Acid Load, Mineral Depletion & the Hidden Link to Histamine Intolerance & Oxalates | 14 Jul 2025 | 00:35:16 | |
In this episode of The Histamine Well, we're diving into one of the most overlooked root causes behind symptoms like fatigue, histamine intolerance, hormonal imbalance, oxalate sensitivity, mood swings, and chronic inflammation: acid load and mineral depletion. You'll learn:
Whether you're a practitioner, student, or someone deep in their own healing journey, this episode will shift how you view symptoms and recovery — especially if you’ve hit a wall despite ‘doing all the right things. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 19. Clinical Insights into PMDD, Severe PMS & the Role of Methylation | 07 Jul 2025 | 00:14:33 | |
In this episode of The Histamine Well, Joanne dives deep into Premenstrual Dysphoric Disorder (PMDD) and severe PMS — the kind that can leave you feeling anxious, depressed, exhausted, and unlike yourself for half the month. Joanne shares insights from her clinical practice to explore what’s really going on beneath the surface, including:
She also introduces the concept of testing methylation in real time, and shares a powerful patient story that shows how personalized treatment can dramatically improve mood and cycle symptoms. Whether you’ve been diagnosed with PMDD or you just know your PMS isn’t normal, this episode offers a fresh perspective and hope for more stable cycles and moods. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 18. Balancing Methylation: A Game-Changer for Mental Health, Perimenopause & Menopause | 30 Jun 2025 | 01:01:06 | |
In this episode of The Histamine Well, host Joanne speaks with Amanda Bradshaw, co-founder of Mood Sense, to explore the critical role methylation plays in mood, mental health, and hormonal transitions like perimenopause. Joanne shares her clinical insights and surprising test results showing that some patients assumed to be under-methylators were actually over-methylating—changing the course of their treatment. Amanda opens up about her personal health journey through perimenopause and how balancing her methylation significantly improved symptoms like mood swings and hot flushes. Together, they unpack how methylation imbalances can impact not just mental health, but also relationships, family dynamics, and even parenting—especially in neurodivergent households. Listeners will also gain practical guidance on how the Mood Sense test works, and how diet, lifestyle, and targeted supplements can help restore balance and support emotional resilience. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 17. How Gluten Causes Immune Dysfunction, Chronic Inflammation and High Histamine | 23 Jun 2025 | 00:24:57 | |
In this episode, Joanne Kennedy discusses a comprehensive case study of a patient with various symptoms like abdominal pain, migraines, and joint pain who was incorrectly suspected of having mold and oxalate problems. The root cause turned out to be gluten intolerance. Joanne explains the impact of gluten on the immune system, highlighting how it can cause significant inflammation and histamine issues. She differentiates between celiac disease, wheat allergy, and non-celiac gluten sensitivity, explaining their symptoms, testing methods, and impacts on histamine production. Joanne also provides insights into diagnosing these conditions and emphasizes the importance of closely examining patients' diets before attributing symptoms to more complex conditions like mold or oxalate issues. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 16. Emotional Eating, Gut Health & Histamine: A Conversation with Amber Romaniuk | 16 Jun 2025 | 00:44:48 | |
In this episode of the Histamine Well Podcast, Joanne is joined by Amber Romanic, an expert in emotional eating, digestion, and hormonal health. Amber shares her personal journey overcoming emotional eating and discusses how it impacts gut health and increases histamine levels. They explore common emotional eating triggers, the role of high cortisol, and the pitfalls of extreme diets like intermittent fasting. Amber offers practical tips on managing emotional eating, the importance of healing one's relationship with food, and why self-care and setting healthy boundaries are crucial. Additionally, they touch on the unique challenges women face during different phases of their menstrual cycles and why maintaining a balanced approach is essential for overall well-being. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 15. The Connection Between High Histamine Levels and Hypoglycemia | 09 Jun 2025 | 00:12:52 | |
In this episode of the Histamine Well Podcast, Joanne explores the surprising link between high histamine levels and hypoglycemia. She details how elevated histamine can disrupt blood sugar regulation through various mechanisms, including overstimulation of insulin production, suppression of glucagon, and cortisol dysregulation. Joanne also offers practical advice on managing high histamine and blood sugar levels through diet, stress management, and lifestyle changes. Tune in to learn more about identifying and addressing histamine-related blood sugar crashes. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 14. Understanding SIBO and Histamine: An In-Depth Discussion with Joanne Kennedy & Melanie Peers | 02 Jun 2025 | 01:01:31 | |
In this episode of the Histamine Well Podcast, Joanne is joined by her colleague Melanie Peers to discuss the relationship between small intestinal bacterial overgrowth (SIBO) and histamine intolerance. They explore the complexities of SIBO, its causes, symptoms, and its impact on histamine levels in the body. Joanne and Melanie also delve into related issues such as the role of the migrating motor complex, the influence of stress, dietary impacts, and the significance of mold, oxalates, and sulfur in exacerbating histamine symptoms. Practical advice on diagnosis, dietary adjustments, and treatment options is provided, making this episode an invaluable resource for both practitioners and individuals seeking to manage their gut health and histamine-related conditions. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 13. The Role of Digestive Enzymes in Gut Health and Histamine Balance | 26 May 2025 | 00:25:03 | |
In this episode of the Histamine Well Podcast, host Joanne Kennedy delves into the significance of digestive enzyme deficiencies in managing histamine intolerance and chronic gut issues like SIBO. Joanne explains the critical roles of hydrochloric acid, pancreatic enzymes, and bile acids in maintaining a healthy digestive system, and how their insufficiencies can lead to increased histamine levels and poor gut health. The episode covers the symptoms, causes, and solutions for enzyme deficiencies, emphasizing the importance of proper enzyme supplementation. Joanne also shares insights into the impacts of stress, diet, and specific medications on enzyme production. This episode is a must-listen for those looking to better understand and manage their digestive health and histamine levels. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 12. The Connection between Methylation, Gallbladder Health & Histamine with Nutritionist Olivia Hass | 19 May 2025 | 00:47:56 | |
In this episode of the Histamine Well podcast, Joanne dives into the connection between methylation, detoxification, and gallbladder health. Joined by nutritionist Olivia Haas, they discuss how impaired methylation affects bile flow, leading to gallbladder dysfunction and increased histamines. Olivia explains the essential role of the gallbladder in digestion, detoxification, and overall health. They cover early warning signs of gallbladder issues, appropriate testing, and the interplay between estrogen dominance, mold, and oxalate sensitivities. Practical recommendations for dietary and supplement support for gallbladder and liver health, both pre- and post-surgery, are also discussed. Olivia also speaks about her specialized programs and memberships designed to assist patients with gallbladder concerns. This episode is packed with insights and actionable advice for both practitioners and patients. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 29. Healing Chronic Illness Through Nervous System Regulation with Jacqui Raadschelders | 13 Oct 2025 | 00:46:51 | |
In this episode of The Histamine Well Podcast, Joanne Kennedy sits down with physiotherapist and neuro-rehabilitation specialist Jacqui Raadschelders to explore the link between nervous system dysregulation and chronic illness. You’ll learn how the limbic system, vagus nerve, neuroplasticity, and brain retraining techniques play a vital role in recovery from conditions influenced by trauma, mold exposure, and stress. Jacqui shares her journey from traditional physiotherapy to a holistic, trauma-informed approach—highlighting the impact of emotions, beliefs, and environment on healing. Key topics include:
Whether you’re a practitioner, student, or someone navigating chronic illness, this conversation offers practical tools and evidence-based insights for restoring balance and supporting your nervous system health. Enrol in the Regulate Your Nervous System online program and receive 10% off with the code JOANNE10. This program is for anyone navigating chronic illness, burnout, stress or persistent symptoms who’s ready to understand their body in a new way. Enrol here ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 11. Practical Tips for Lowering Histamine Levels Quickly | 12 May 2025 | 00:20:28 | |
In this episode of the Histamine Well Podcast, Joanne does something a little different. She shares her step-by-step approach for rapidly lowering your histamine bucket while working toward identifying and treating the root cause. This episode is packed with clinical gems and practical strategies—perfect for both patients and practitioners. In this episode, you’ll learn:
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 10. Practitioner's Perspective - Managing Complex Cases of SIBO, Histamine, Oxalates & Mould | 05 May 2025 | 00:38:01 | |
In this episode of the Histamine Well Podcast, Joanne is joined by Naturopath Mariela Gebhardt from Austria to discuss a fascinating and complex case. Initially thought to be related to SIBO, Mariela shares how, despite seeing early improvement in her patient's gut health, she remained in a heightened anxious state and developed an unusual symptom: toe pain. Mariela identified this as an oxalate issue, which was later confirmed through Organic Acids testing. This discovery prompted Mariela to inquire further about mould exposure, which quickly became clear as a significant factor. Mariela humbly acknowledges that the mould and oxalate issue should have been identified during the initial consultation, but, due to her lack of training in this area at the time, it wasn’t immediately apparent. However, after mentoring with Joanne and her colleague Melanie Peers, her perspective shifted, and she now approaches these cases with greater insight. This episode is a must-listen for anyone dealing with chronic histamine issues, as well as practitioners and students interested in more complex cases. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 9. Health Implications of Low Homocysteine – A Clinical Perspective | 28 Apr 2025 | 00:29:09 | |
In this episode of the Histamine Well Podcast, host Joanne delves into the often-overlooked topic of low homocysteine levels. Joanne explains that while high homocysteine is commonly flagged for its cardiovascular risks, low homocysteine is seldom discussed despite its significant implications for health. She explores how low homocysteine can indicate sulfur depletion, often linked to issues such as oxalate toxicity and mold illness. The episode covers the methylation process, the importance of methionine, and the roles of cysteine, glutathione, and taurine. Joanne also discusses the impact of stress, diet, and poor absorption on homocysteine levels and underscores the connection between oxalates and sulfur depletion. Whether you are a practitioner or navigating your personal wellness journey, this episode provides actionable insights into understanding and addressing low homocysteine to improve overall health. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 8. Insights Into Over & Under Methylation with Scientist James Bradshaw | 21 Apr 2025 | 01:12:24 | |
In this episode of the Histamine Well, Joanne is joined by scientist James Bradshaw to discuss the complexities of methylation and its critical role in genetics, mood, and overall health. James shares his extensive background in biochemistry and cellular biology and introduces Mood Sense, the first saliva test for assessing methylation-related mood disruptions. They explore the essentials of methylation, its impact on neurotransmitter production, and the difference between over and under methylation. The episode also delves into genetic mutations, environmental factors affecting methylation, and practical approaches to managing methylation in clinical practice. Listeners gain insights into the role of methylation in various chronic health conditions and how personalized testing can lead to better health outcomes. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 7. MTHFR, Methylation, Folic Acid & Folate Testing - A Clinical Perspective | 14 Apr 2025 | 00:21:53 | |
In this episode of The Histamine Well Podcast, Joanne dives deep into the topic of MTHFR, an enzyme crucial for the process of methylation. Joanne explains the significance of methylation in various biochemical and genetic processes such as detoxification, neurotransmitter regulation, and genetic expression. The episode also addresses why methylfolate is essential, discusses common causes of methylfolate deficiency, and highlights why folic acid can be problematic for everyone. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 6. Understanding Multiple Food Intolerances: Histamine, Oxalates, Sulfur and More! | 07 Apr 2025 | 00:17:36 | |
In this episode of The Histamine Well, Joanne breaks down the complexities of multiple food intolerances. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 5. Practitioner's Perspective- Managing SIBO and Hormonal Imbalances Without Testing: A Practical Approach | 31 Mar 2025 | 00:35:21 | |
In this episode of the Histamine Well Podcast, Joanne is joined by naturopath Bridget Greenall to discuss Small Intestinal Bacterial Overgrowth (SIBO), particularly focusing on how to diagnose and treat it without testing. They explore the intertwined issues of SIBO, inflammation, and blood sugar dysregulation and their impact on hormonal health, including PMS and hot flushes. The conversation provides practical insights for practitioners, students, and patients on managing SIBO, especially under financial or geographical constraints that prevent testing. Additionally, they touch upon the significance of methylation in addressing hormonal imbalances and introduce an at-home saliva methylation test. The episode wraps up with detailed case studies, addressing facets of SIBO treatment and related hormonal symptoms. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 4. Balancing Oestrogen & Histamine: What Every Woman Should Know | 24 Mar 2025 | 00:26:06 | |
In this episode of the Histamine Well podcast, Joanne delves into the intricate relationship between histamine and oestrogen. She explores how histamine can stimulate excess oestrogen production and vice versa, leading to a range of symptoms such as migraines, dizziness, anxiety, and digestive issues. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 3. Are Oxalates Causing Your Histamine Intolerance and Lowering Homocysteine? | Featuring Melanie Peers | 17 Mar 2025 | 01:19:02 | |
In this episode of the Histamine Well podcast, Joanne is joined by her colleague, Melanie Peers, an expert in oxalate issues. Together they explore the complex world of oxalates, their profound impact on histamine intolerance, methylation pathways, and overall health. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 2. Main Causes of Histamine Intolerance: What's Behind The Symptoms | 10 Mar 2025 | 01:07:46 | |
High histamine levels are often a signal of deeper imbalances, and in this episode of The Histamine Well, we’re uncovering the hidden root causes that could be driving your symptoms. From SIBO and gluten intolerance to leaky gut and methylation issues, we’ll explore why histamine intolerance is rarely just about food and how addressing the underlying factors can lead to real, lasting solutions. Whether you’re managing your own health, supporting others on their journey as practitioner, this episode will empower you with insights that go far beyond symptom management, helping you get to the “why” behind histamine issues. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 28. Oxalates, Adrenal Fatigue & Blood Sugar Imbalance: Tracy’s Journey to Healing | 29 Sep 2025 | 01:08:58 | |
In this episode of The Histamine Well Podcast, Joanne is joined by colleague Melanie and patient Tracy, who shares her powerful story of navigating the challenges of oxalates, histamine intolerance, adrenal fatigue, and blood sugar imbalances. Tracy’s journey highlights the complex relationship between oxalates, adrenal and blood sugar imbalances, and oxalate dumping symptoms. With support from Melanie, she has worked through paradoxical reactions to magnesium and B6, learned strategies for managing sulfur metabolism, and discovered the importance of patience and persistence in recovery. Melanie provides expert insights into identifying oxalate issues, tailoring dietary strategies, and supporting detoxification pathways. Together, the conversation emphasizes the importance of professional guidance, careful supplementation, and tracking progress when addressing oxalates. Whether you’re a practitioner seeking functional medicine insights or someone personally struggling with oxalates, histamine intolerance, or methylation challenges, this episode offers practical advice and encouragement to support your healing journey.
Oxalates are often overlooked in discussions about chronic health, but they can play a major role in gut health, nutrient absorption, adrenal function, and histamine intolerance. Tracy’s story shows how challenging—but also how rewarding—it can be to address these issues with the right support and strategies. If you’ve been struggling with fatigue, blood sugar swings, or unexplained reactions to supplements, this conversation offers valuable guidance. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 1. Understanding Histamine: How it Works and What Happens When it's Too High | 03 Mar 2025 | 00:35:38 | |
In the inaugural episode of the Histamine Well Podcast, Joanne, introduces the nuanced topic of histamine intolerance. Designed for both health practitioners and patients, the episode breaks down the science behind histamine, its role in the body, the widespread issue of chronic inflammation driving up histamine levels, and the symptoms it causes such as skin issues, gastrointestinal problems, anxiety, migraines, insomnia and hormonal imbalances. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Welcome to The Histamine Well: Navigating Health Challenges with Joanne Kennedy | 19 Feb 2025 | 00:01:50 | |
Welcome to The Histamine Well with your host, Joanne Kennedy. In this introductory episode, Joanne shares the purpose behind the podcast and what you can expect in future episodes. Whether you’re a practitioner or someone living with chronic health challenges like gut issues, skin problems, hormonal imbalances, fatigue, or food intolerances, this podcast is here to provide clarity and support. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 27. Why Blood Tests & Functional Medicine Tests Aren’t the Full Story: Gut, Histamines, Genes, Hormones & More! | 15 Sep 2025 | 00:47:16 | |
In this episode of The Histamine Well Podcast, host Joanne Kennedy and guest Mariella Gebhardt unpack the nuances of medical testing in functional medicine—and why lab results alone don’t always tell the full story. From histamine intolerance and methylation issues to gut health, Candida, mold exposure, and hormone imbalances, Joanne and Mariela explore the limitations and benefits of testing while emphasizing the importance of case history, symptoms, and environmental factors in shaping treatment. They break down popular tests—including organic acids tests (OAT), microbiome testing, genetic testing, thyroid panels, iron tests, and hormone testing—highlighting when they’re useful, what they may miss, and how to interpret them in real-world practice. Whether you’re curious about functional medicine, women’s hormones, SIBO, oxalates, DAO enzyme activity, or vitamin B12 deficiency, this episode offers clarity on when testing helps—and when it can be misleading. What You’ll Learn in This Episode:
If you’ve ever wondered whether your test results reflect the whole picture—or how to navigate functional medicine testing with confidence—this conversation will help you understand the bigger picture. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 26. Mold & Chronic Illness: Symptoms, Testing, and Detox Strategies with Melanie Peers | 01 Sep 2025 | 00:54:05 | |
Could mold be the missing link in your chronic health puzzle? In this episode of The Histamine Well Podcast, Joanne speaks with Melanie Peers about the hidden impact of mold illness and how it can silently drive histamine intolerance, food sensitivities, and long-term inflammation. You’ll discover how mold exposure can:
Melanie shares how to spot the difference between everyday mold allergies and systemic mold-related illness, how to test for mold in your home and body, and what a mold detox protocol can look like in real life. Whether you’re a health practitioner or someone struggling with unexplained symptoms, this episode gives you practical strategies for identifying mold, removing exposure, and supporting recovery. What You’ll Learn in This Episode
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 25. Energy Healing Essentials for Perimenopause: A Discussion with Claire Tait | 18 Aug 2025 | 01:02:01 | |
Perimenopause isn’t just a physical transition — it’s an emotional, spiritual, and energetic shift. In this empowering episode of The Histamine Well Podcast, Joanne speaks with Claire Tait, a holistic kinesiologist and intuitive energy healer, about how to navigate perimenopause with greater balance, calm, and self-awareness. Claire shares her expertise on how kinesiology, reiki, acupressure, yoga, and other holistic practices can support women during this powerful life stage. You’ll learn how to regulate your nervous system, address anxiety naturally, and embrace the spiritual metamorphosis of perimenopause. This conversation is filled with practical rituals, personal insights, and empowering perspectives to help you surrender to the changes, reconnect with yourself, and thrive during midlife. What You’ll Learn in This Episode:
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 24. Histamine & Anxiety – How High Histamine Triggers Fight-or-Flight Symptoms | 11 Aug 2025 | 00:31:10 | |
Can histamine be the hidden reason behind your anxiety? ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 23. Could Your Histamine Intolerance Actually Be Sulfur Intolerance? | 04 Aug 2025 | 00:56:15 | |
We break down how disrupted sulfur metabolism can mimic histamine symptoms—severe bloating, crushing fatigue, joint pain, brain fog, skin flushing—and why reactions to garlic, onions, eggs, brassicas, NAC, and glutathione are key clues. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 22. PMDD, Histamine Intolerance & Methylation: Anastasia’s Journey from Breakdown to Breakthrough | 28 Jul 2025 | 00:37:09 | |
In this deeply personal and powerful episode, Joanne sits down with patient Anastasia Lamont to explore her journey through PMDD (Premenstrual Dysphoric Disorder), histamine intolerance, and overmethylation. Anastasia opens up about the debilitating symptoms she endured — from suicidal ideation and extreme fatigue to chronic pain and severe skin conditions — and how her life transformed through targeted naturopathic treatment. Together, they unpack the emotional and clinical journey, revealing the role of diet, supplements, and real-time methylation testing in stabilizing mood and reclaiming wellness. This is a must-listen for anyone living with PMDD or supporting someone who is — and for practitioners looking to understand the powerful intersection between mood, hormones, and histamine. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 32. Hormone Replacement Therapy in Perimenopause: Interview with Rachel Schaefer | 12 Jan 2026 | 01:13:46 | |
Are your hormones out of balance? In this episode of The Histamine Well Podcast, Joanne sits down with Rachel Schaefer, founder of Ginkgo Integrative Medicine, to demystify perimenopause and the role of Hormone Replacement Therapy (HRT) in supporting women’s health. They explore what actually happens during hormone fluctuations in perimenopause, how to recognize estrogen dominance, and the benefits and risks of estrogen, progesterone, and testosterone therapy. Rachel shares practical insights on how personalized care, detailed hormone testing, and integrative medicine can help women navigate this transitional stage with confidence. You’ll learn how early intervention with the right HRT protocol can improve energy, mood, sleep, and long-term wellbeing—plus how to avoid common pitfalls with synthetic hormones, patches, and oral estrogen. Whether you’re just entering perimenopause or already considering HRT, this episode offers a clear, empowering look at how to restore hormonal harmony and thrive through midlife. Learn more about Rachel’s integrative approach to hormone health and women’s wellbeing:
🧪 Rachel’s Recommended Annual Serum Lab Panel (Age 40+) Done fasting, ideally once per year. Tracks hormonal shifts & key biomarkers: Additional testing based on the case: DUTCH · Tiny Health GI Pro · Mira · 3x4 Genetics · Total Tox Burden · DEXA · OATS · Mood Sense 💡 At-Home Hormone Tracking — Listener Discount Rachel checked in with Mira, a home-based hormone urine testing device, to offer a special 20% off discount for listeners of The Histamine Well Podcast. 🔸 Public Discount Code: 2GINGKO20 ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 34. Vitamin B12 Explained: Forms, Methylation, Homocysteine & Absorption | 02 Feb 2026 | 00:48:04 | |
In this episode of The Histamine Well Podcast, Joanne is joined by scientist James Bradshaw for an in-depth discussion on Vitamin B12 and its critical role in human health. Together, they unpack the complex biochemistry of Vitamin B12, exploring how it supports methylation pathways, homocysteine metabolism, and neurological function. This episode provides clarity on why Vitamin B12 deficiency is often overlooked, how genetic variations can impact B12 utilization, and why choosing the correct form of B12 supplementation is essential for optimal outcomes. Joanne and James also examine the different forms of Vitamin B12—including methylcobalamin, hydroxocobalamin, adenosylcobalamin, and cyanocobalamin—discussing how each functions in the body and when one may be more appropriate than another. The conversation highlights common signs and symptoms of B12 deficiency, from fatigue and brain fog to neurological and mood-related concerns, and offers practical, evidence-informed strategies for assessing and supporting B12 status. This episode is especially valuable for health practitioners, functional medicine clinicians, and individuals seeking a deeper understanding of how Vitamin B12, genetics, and methylation intersect to influence long-term health.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 33. Over-Methylation Explained: COMT, Estrogen, Mood & Inflammation | 26 Jan 2026 | 00:11:18 | |
In this episode of the Histamine Well Podcast, Joanne Kennedy explains why over-methylation is becoming increasingly common, especially among women, and how it’s closely linked to COMT enzyme activity, estrogen dominance, mood disorders, and inflammation. This episode breaks down the biochemistry of methylation in a clear, practical way—exploring how estrogen affects COMT, why some people react badly to methylated B vitamins, and how over-methylation can drive symptoms such as anxiety, irritability, insomnia, nervous system overload, and chronic inflammation. Joanne also introduces the Mood Sense test as a real-time tool for assessing methylation status, helping practitioners and individuals move away from guesswork and toward personalized, symptom-aware support. With insights inspired by James Bradshaw, this episode is essential listening for anyone navigating estrogen-related symptoms, mood instability, or complex supplement reactions.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Q&A. Why Do I Still Have Inflammation When My CRP & ESR Are Normal? | 08 Apr 2026 | 00:03:23 | |
If your blood tests are “normal”… why do you still feel inflamed? In this Q&A Clarity Session of The Histamine Well Podcast, Joanne answers a deeply important and often overlooked question: why symptoms of inflammation can persist even when CRP and ESR markers come back normal. Many people are told everything is “fine” based on standard blood work—yet continue to experience fatigue, brain fog, skin issues, gut dysfunction, and hormonal imbalances. This episode explains why that disconnect happens and what may actually be driving your symptoms. CRP (C-reactive protein) and ESR (erythrocyte sedimentation rate) are commonly used markers for inflammation—but they primarily detect acute, systemic inflammation, not the chronic low-grade inflammation seen in many complex health conditions. In this episode, you’ll learn:
If you’ve ever been told “your labs are normal” but still don’t feel well, this episode will give you the clarity and validation you’ve been looking for. This is essential listening for anyone dealing with:
🎧 Subscribe to The Histamine Well Podcast for more expert insights on root-cause healing, inflammation, and complex chronic conditions. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 42. Why Your Hormones Haven't Improved Despite Treatment - The Role of Inflammation, Histamine & Methylation | 06 Apr 2026 | 00:13:49 | |
In this in-depth episode of The Histamine Well Podcast, Joanne explores why hormone symptoms often persist despite treatment, and what may be driving this beneath the surface. Drawing on clinical observation and biochemistry, Joanne explains how chronic inflammation, histamine dysregulation, and methylation imbalances interact to disrupt hormonal signaling, ovulation, and recovery. If you’ve tried supplements, improved your diet, and still experience symptoms like PMS, PMDD, anxiety, insomnia, migraines, or hormonal acne, this episode provides a deeper framework for understanding why.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Q&A. What Type of Magnesium Should I Take? | 04 Mar 2026 | 00:07:17 | |
In this short Clarity Session Q&A, Joanne explains the key differences between common magnesium forms and how to choose the right one for symptoms like anxiety, sleep issues, constipation, migraines, fatigue, muscle pain, or brain fog. Learn when each type may help—and when to avoid certain forms if you’re sensitive. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 37. Candida and Histamine: Why Fungal Overgrowth Keeps Coming Back | 02 Mar 2026 | 00:14:12 | |
In this episode of The Histamine Well Podcast, Joanne explores how candida, yeast, and fungal overgrowth can worsen histamine intolerance and trigger ongoing mast cell symptoms. She explains how fungal-driven gut inflammation increases histamine production by activating mast cells, upregulating histidine decarboxylase (HDC), and reducing DAO enzyme activity — making it harder for the body to break histamine down. You’ll learn why antifungals alone often fail, how gut “terrain” factors like low stomach acid, poor bile flow, digestive enzyme insufficiency, microbiome imbalance, mold exposure, and chronic stress allow fungal overgrowth to persist, and how SIBO and SIFO are connected through small intestinal pH imbalance. If you struggle with histamine intolerance, sugar cravings, brain fog after carbs, bloating, or recurrent candida, this episode explains the deeper root causes — and why nervous system regulation is essential for long-term healing. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Q&A. Should I Be Taking Antihistamines Long Term? | 25 Feb 2026 | 00:04:23 | |
In this short Clarity Session Q&A bonus episode of The Histamine Well Podcast, Joanne explains what antihistamines actually do, why symptoms often return when you stop them, and the common root causes behind histamine issues. Learn the difference between symptom suppression and true regulation of the gut, detox pathways, and nervous system. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 36. Less Is More: Why Over-Treating Mold & Food Intolerance Makes Things Worse | 23 Feb 2026 | 00:38:45 | |
In this episode of the Histamine Well Podcast, Joanne speaks with Rachel Scott, who developed severe food intolerances, intense histamine reactions, and unexplained chronic symptoms following mold exposure. After years of misdiagnosis and treatments that failed to address the root cause, Rachel’s health continued to deteriorate — until a simpler, more balanced approach was introduced. Rachel shares how targeted support using sulforaphane, digestive enzymes, and Epsom salt baths helped stabilize her system and gradually restore tolerance to food. Joanne explains the biochemical drivers behind mold-related illness, including sulfur metabolism, detoxification pathways, and nervous system load, and why aggressive protocols, heavy supplementation, and herbal overuse can often worsen symptoms in sensitive individuals. This conversation highlights the importance of gentle, well-timed interventions, practitioner guidance, and understanding the body’s capacity before pushing detoxification. Topics covered include:
Show Notes: 🌐 Official Program Links 1. The Gupta Program – Brain Retraining This is the main site for the limbic retraining and neuroplasticity program designed to help calm the nervous system and support recovery from chronic and sensitivity-related conditions. 2. Irene Lyon – Somatic & Nervous System Work This is the official site for Irene Lyon, a nervous system expert who provides somatic-based exercises and education to help regulate the nervous system body-mind connection. 3. Cell‑Logic – G.E.M.M. Protocol for Patients This page explains the G.E.M.M. Protocol (Gut Ecology & Metabolic Modulation) — an approach focused on restoring cellular health and gut-immune balance. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Q&A. If I have MTHFR Does it Mean I Can't Detox? | 18 Feb 2026 | 00:05:38 | |
In this Clarity Session, Joanne breaks down a common myth about the MTHFR gene, methylation, and detox. Does having an MTHFR variant mean your detox pathways are impaired? Learn how detoxification really works, how methylation fits in, and what actually supports healthy histamine balance, gut health, and energy. Perfect for anyone navigating MTHFR, chronic fatigue, or food sensitivities. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 35. Understanding MARCoNS and Its Impact on Inflammation, Histamine, and Chronic Symptoms | 16 Feb 2026 | 00:09:50 | |
In this episode of The Histamine Well Podcast, Joanne takes a deep dive into MARCoNS (Multiple Antibiotic Resistant Coagulase-Negative Staphylococci)—a frequently overlooked bacterial colonization that can drive chronic inflammation, histamine intolerance, and persistent, unexplained symptoms. Joanne explains how MARCoNS colonize the nasal passages, often in the context of mould-related illness, and why these bacteria are particularly difficult to eradicate due to their ability to form protective biofilms. She explores the connection between MARCoNS and symptoms such as fatigue, brain fog, migraines, anxiety, poor detoxification, and heightened inflammatory responses, especially in individuals who don’t improve despite targeted gut or histamine protocols. This episode walks listeners through how MARCoNS are identified, with a focus on nasal swab testing, and outlines evidence-informed treatment strategies, including biofilm disruptors, targeted herbal antimicrobials, and supportive therapies designed to reduce bacterial load and calm immune activation. Whether you’re a health practitioner working with complex chronic cases or an individual struggling with ongoing symptoms that don’t fully resolve, this episode provides practical insight into MARCoNS as a hidden driver of inflammation and histamine dysregulation. In This Episode, You’ll Learn:
Joanne discusses laboratories that provide MARCoNS (Multiple Antibiotic Resistant Coagulase-Negative Staphylococci) nasal swab testing, commonly used in clinical practice to identify bacterial colonisation linked to chronic inflammation, histamine-related symptoms, and mould-associated illness.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Q&A. Are Bioidentical Hormones Actually Natural? | 01 Apr 2026 | 00:03:00 | |
Are bioidentical hormones truly “natural”—or is that just clever marketing?
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 41. Can’t Tolerate HRT? The Hidden Reason Most Women Miss | 30 Mar 2026 | 00:12:03 | |
Can’t tolerate HRT? This episode explores the connection between histamine intolerance, hormone replacement therapy (HRT), SIBO, gut health, menopause symptoms, and hormone imbalance in women. Joanne Kennedy shares a clinical case study showing how histamine overload and gut dysfunction can worsen HRT side effects like brain fog, fatigue, mood swings, and skin reactions. Learn how the estrogen-histamine connection, gut health, and inflammation impact hormone tolerance—and why addressing SIBO and histamine intolerance may help restore balance. Perfect for women experiencing menopause symptoms, HRT intolerance, or ongoing hormone imbalances. 🌿 In This Episode, You’ll Learn:
For worldwide online consultations via Zoom, visit: www.joannekennedynaturopathy.com ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Q&A. How Does Sulforaphane Work in the Body? Hint: It Switches On Your Protective Genes | 25 Mar 2026 | 00:03:51 | |
In this Q&A Clarity Session of The Histamine Well Podcast, naturopath Joanne Kennedy explains the science behind sulforaphane and how it activates the NRF2 pathway, often referred to as the body’s “master switch” for protection and repair. Rather than acting as a simple antioxidant, sulforaphane works at a deeper level—helping to switch on a network of protective genes responsible for detoxification, antioxidant production, inflammation control, and immune regulation This episode breaks down complex science into simple, practical insights—perfect for both practitioners and those navigating chronic health issues. In This Episode, we discussed:
Who This Episode Is For:
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 40. The GEMM Protocol: A Deeper Approach To Why Your Gut Isn't Healing - And What To Do About It | 23 Mar 2026 | 00:51:51 | |
In this episode of The Histamine Well Podcast, Joanne speaks with nutritional biochemist Dr. Christine Houghton about the GEMM Protocol (Gut Ecology & Metabolic Modulation) — a science-based approach to restoring gut health by repairing the gut lining and activating protective genes.
✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Q&A. Should I Take Antibiotics for SIBO? | 18 Mar 2026 | 00:05:09 | |
In this Q&A Clarity Session of The Histamine Well Podcast, Joanne answers a common and often confusing question: Should I take antibiotics for SIBO? ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| 39. Why Does Your SIBO Keep Coming Back? (And What Most Treatments Miss) | 16 Mar 2026 | 00:13:50 | |
Is SIBO (Small Intestinal Bacterial Overgrowth) really the root cause of your bloating and food intolerances — or is it a downstream effect of deeper dysfunction? In this episode of The Histamine Well Podcast, Joanne explains why SIBO rarely develops in isolation and why antibiotics or herbal antimicrobials alone often fail to prevent relapse. If you’ve been stuck in the cycle of treating SIBO repeatedly without lasting improvement, this episode explores the underlying mechanisms that may be driving bacterial overgrowth in the first place. Joanne unpacks how impaired gut motility, nervous system dysregulation, low stomach acid, sluggish bile flow, estrogen dominance, mold toxicity, thyroid dysfunction, and histamine intolerance all contribute to creating the perfect environment for SIBO to thrive. Rather than focusing solely on eliminating bacteria, this episode highlights a terrain-based, root-cause approach to restoring long-term digestive health.
If you found this episode helpful, please subscribe, leave a review, and share it with someone navigating SIBO or chronic gut issues. For worldwide online consultations via Zoom, visit: www.joannekennedynaturopathy.com ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||
| Q&A. How Is Methylation Connected to Mental Health? | 11 Mar 2026 | 00:06:07 | |
In this Q&A episode, we explore how methylation affects mental health, including its impact on neurotransmitters like dopamine, serotonin, and norepinephrine. Learn how the methylation cycle regulates gene expression, hormone balance, histamine clearance, and stress resilience — and why low folate, vitamin B12, B6, and B2 can contribute to symptoms such as anxiety, depression, brain fog, fatigue, insomnia, and “wired but tired” patterns. We also discuss slow COMT activity, the link between estrogen and histamine, and how imbalances can drive mood swings, palpitations, and poor stress tolerance. Discover how real-time methylation testing (Mood Sense saliva swab) can provide personalised insights, plus how to book a Zoom consultation for deeper support. If you're struggling with histamine intolerance, hormone imbalance, anxiety, or low mood, this episode connects the biochemical dots. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off. 🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026! 📆 Work with us 1:1! Book a consultation and take your first step to real healing. | |||