Inside Scope – Details, episodes & analysis

Enhance your patient care skills with this season covering select AGA Clinical Practice Updates. Originally released as a bonus episode in January 2023, this episode shares key insights from the AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease (published in the February 2021 issue of Gastroenterology). This episode is hosted by Dr. Jana Al Hashash, member of the AGA Clinical Practice Update Committee. She is joined by: -Dr. Heather Patton, NAFLD expert and past member of the AGA Clinical Practice Update Committee -Dr. Joseph K. Lim, past chair of the AGA Clinical Practice Update Committee and co-author of this CPU -Dr. Zobair M Younossi, co-author of this CPU To access the full expert review, visit www.gastro.org/CPU.

Enhance your patient care skills with this season covering select AGA Clinical Practice Updates. This episode shares key insights from the AGA Clinical Practice Update: Diet and Nutritional Therapies (published in the March 2024 issue of Gastroenterology). This episode is hosted by Dr. Jana Al Hashash, chair of the AGA Clinical Practice Update Committee. She is joined by authors -Dr. David Binion, professor of medicine and co-director of the IBD Center, director of nutrition support service, at UPMC Presbyterian Hospital and University of Pittsburgh; co-author of CPU -Dr. James Lewis, professor of medicine and epidemiology at the Perelman School of Medicine at the University of Pennsylvania ; co-author of CPU -Ms. Kelly Issokson, registered dietitian and clinical coordinator of digestive diseases at Cedars-Sinai in Los Angeles To access the full Clinical Practice Update, visit www.gastro.org/CPU.

Welcome to our six-part series: Increasing Diversity in IBD Clinical Trials. This program will explore how to become a clinical trialist and increase diversity in IBD clinical trials. In this supersized episode, co-host Dr. Ayanna Lewis is joined by guest Dr. Ryan Stidham, an associate professor at the University of Michigan holding appointments in the departments of medicine and computational medicine. Dr. Stidham is a medical data scientist and has a research program that focuses on the development and testing of new technologies for disease assessment and decision making in gastroenterology and general medicine. Today’s discussion will explore how artificial intelligence may help address challenges with participant recruitment for clinical trials, while also discussing the role of AI in the field of gastroenterology more broadly. This series is supported by educational grants from AbbVie Inc.; Amgen; Bristol-Myers Squibb Company; Genentech, a member of the Roche Group; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A., Inc., and a quality improvement grant from Pfizer Inc.

Welcome to our six-part series: Increasing Diversity in IBD Clinical Trials. This program will explore how to become a clinical trialist and increase diversity in IBD clinical trials. In this episode, co-host Dr. Ayanna Lewis is joined by guest Dr. Erica Cohen, an adult gastroenterologist, IBD specialist and director of the IBD Research Program at Capital Digestive Care in Washington, D.C. Today’s discussion focuses on the community GI’s perspective on clinical trials. This series is supported by educational grants from AbbVie Inc.; Amgen; Bristol-Myers Squibb Company; Genentech, a member of the Roche Group; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A., Inc., and a quality improvement grant from Pfizer Inc.

Welcome to our six-part series: Increasing Diversity in IBD Clinical Trials. This program will explore how to become a clinical trialist and increase diversity in IBD clinical trials. In this episode, co-host Dr. Erin Forster is joined by guest Kenneth Getz, professor of public health and community medicine and director of the Center for the Study of Drug Development at Tufts University School of Medicine. Ken is also the founder and chairman of the board of directors at CISCRP, a nonprofit dedicated to providing education and information about clinical research. Today's discussion will explore how we can bring awareness of and education on clinical research to the community. This series is supported by educational grants from AbbVie Inc.; Amgen; Bristol-Myers Squibb Company; Genentech, a member of the Roche Group; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A., Inc., and a quality improvement grant from Pfizer Inc.

Welcome to our six-part series: Increasing Diversity in IBD Clinical Trials. This program will explore how to become a clinical trialist and increase diversity in IBD clinical trials. In this episode, co-host Dr. Erin Forster is joined by guest Dr. Gabriela Radulescu, vice president of medical research and development at Alimentiv, a contract research organization (CRO) specializing in gastroenterology trials. Dr. Radulescu has more than 20 years of experience working in the pharmaceutical industry across multiple functions, including medical affairs, drug safety and pharmacovigilance, clinical research, real world evidence, and patient support programs. At Alimentiv, Dr. Radulescu provides medical leadership for sponsored clinical trials, operational oversight for R&D projects, and medical input to the business development teams. Today’s discussion will explore how CROs are working with investigators and sponsors to increase the diversity of patients enrolling in clinical trials. This series is supported by educational grants from AbbVie Inc.; Amgen; Bristol-Myers Squibb Company; Genentech, a member of the Roche Group; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A., Inc., and a quality improvement grant from Pfizer Inc.

Welcome to our six-part series: Increasing Diversity in IBD Clinical Trials. This program will explore how to become a clinical trialist and increase diversity in IBD clinical trials. In this episode, hosts Drs. Erin Forster and Ayanna Lewis are joined by Melodie Narain-Blackwell, the founder and president of Color of Crohn’s & Chronic Illness (COCCI). COCCI is a nonprofit dedicated to health equity in BIPOC communities that are challenged with digestive diseases and chronic illnesses. Melodie was diagnosed with Crohn’s disease at the age of 36, thirty years after her symptoms began, and has become a passionate health advocate for people of color who battle chronic illness. Today’s discussion focuses on how we talk about clinical research with patients. This series is supported by educational grants from AbbVie Inc.; Amgen; Bristol-Myers Squibb Company; Genentech, a member of the Roche Group; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A., Inc., and a quality improvement grant from Pfizer Inc.

Welcome to our six-part series: Increasing Diversity in IBD Clinical Trials. This program will explore how to become a clinical trialist and increase diversity in IBD clinical trials. In this episode, hosts Drs. Erin Forster and Ayanna Lewis are joined by Drs. Freddy Caldera and Jana Al Hashash, who were part of the inaugural class of participants in AGA’s GI Clinical Trialists Bootcamp program. Today’s discussion focuses on how diversifying participation in clinical trials starts with diversifying our workforce. This series is supported by educational grants from AbbVie Inc.; Amgen; Bristol-Myers Squibb Company; Genentech, a member of the Roche Group; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A., Inc., and a quality improvement grant from Pfizer Inc.

Dr. G.S. Raju, editor of the Gastro Grand Rounds section in Gastroenterology, is joined by Dr. David Ballard and Dr. Parakkal Deepak to discuss their Gastro Grand Rounds article, "Long-Standing Symptomatic Fistulizing Perianal Crohn’s Disease: Progression Beyond Inflammation." https://www.gastrojournal.org/article/S0016-5085(23)04997-1/fulltext Dr. Ballard is an assistant professor of radiology and director of the 3D Printing Lab at the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis. Dr. Deepak is an Associate Professor of Medicine in the Division of Gastroenterology at Washington University School of Medicine in St. Louis. [0:27] Introduction of the authors and outline of the case. [2:29] What initial steps does a gastroenterologist take to manage a patient who presents with possible perianal Crohn’s disease? [6:47] How does an imaging specialist plan for imaging of the perianal disease, and what techniques are used in support of the endoscopist or gastroenterologist? [11:33] The role of point-of-care ultrasound in perianal disease. [15:38] When is a colorectal surgeon brought on board, and what does a colorectal surgeon do when examining the patient? [19:57] How does the clinician manage abscess and fistula? [25:13] Are there any radiological signs that indicate that a particular fistula may be particularly difficult to manage? [29:38] What is a standard treatment for perianal fistula that evolves to cancer? [31:27] Did the patient notice a change in the nature of the discharge? [32:35] Final thoughts from the authors. Thank you for listening. Find this and other articles on our website at https://www.gastrojournal.org. We welcome your feedback. Please email us at gastro@gastro.org. This discussion was recorded on Nov. 1, 2023, and reflects medical knowledge at that time. The views and opinions expressed in this podcast are those of the individual speakers only and do not necessarily represent those of the American Gastroenterological Association. The content of this podcast is provided for general information purposes only and does not offer medical or any other type of professional advice.

Welcome to the first in a series of new podcast episodes from the pages of Gastroenterology, the flagship journal of the American Gastroenterological Association and the most prominent journal in the field of gastrointestinal disease. This podcast series covers articles in the journal’s “Gastro Grand Rounds” section, which features discussions among multidisciplinary teams of experts on the management of complex clinical cases. Gastro Grand Rounds: Managing Diverticulitis Dr. G.S. Raju, editor of the Gastro Grand Rounds section in Gastroenterology, is joined by Dr. Lisa Strate to discuss her article, “Recurrent Lower Abdominal Pain, Altered Bowel Habits, and Malaise: Conservative or Surgical Approach to a Common Disorder.” https://www.gastrojournal.org/article/S0016-5085(23)00042-2/fulltext Dr. Strate is a professor of medicine at the University of Washington School of Medicine and is the section head of gastroenterology at Harborview Medical Center. Dr. Strate’s research has examined risk factors for the development of diverticular disease. Her work has informed the development of guidelines, dietary recommendations, and measurements for the prevention of diverticulitis. She has investigated the role of chronic inflammation and the gut microbiome in diverticulitis. She is a fellow of AGA. [0:27] Introduction of the author. [2:20] The utility of CT in evaluating diverticulitis. [5:49] Managing a patient with uncomplicated diverticulitis. [11:00] Take-home instructions for the patient. [14:12] Preparing the patient colonoscopy, strategies used during the procedure, and documenting findings. [19:11] Utility of a barium enema. [20:22] The patient returns and has left lower quadrant pain. What are the next steps? [24:30] Laying out the pros and cons of continued medical management compared with surgery for a patient who has recurrent episodes of uncomplicated diverticulitis. [28:00] Does the author’s institution have a support group for patients? [28:55] What is the longest period of antibiotics the author has given to a patient who does not want surgery? [30:34] Take-home messages for fellows and residents. Thank you for listening. Find this and other articles on our website at https://www.gastrojournal.org. We welcome your feedback. Please email us at gastro@gastro.org. This discussion was recorded on Sept. 5, 2023, and reflects medical knowledge at that time. The views and opinions expressed in this podcast are those of the individual speakers only and do not necessarily represent those of the American Gastroenterological Association. The content of this podcast is provided for general information purposes only and does not offer medical or any other type of professional advice.