Infectious Disease Puscast – Details, episodes & analysis

On episode #61 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/1/20 - 8/14/24. 

Host: Daniel Griffin and Sara Dong

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• Viral
• nPEP quick guide (AIDS Education & Training Center Program)
• Coformulated Bictegravir/Emtricitabine/Tenofovir Alafenamide PREP after sexual assault (OFID)
• Adopting Early Testing for Perinatal Hepatitis C (Journal of Pediatric Infectious Diseases Society)
• Bacterial
• Lower Rates of Staphylococcus aureus Bloodstream Infection in Patients on Hemodialysis Receiving Trimethoprim-Sulfamethoxazole Melioidosis Prophylaxis (OFID)
• Trimethoprim-Sulfamethoxazole for Staphylococcus Aureus Bacteremia Prophylaxis in Patients on Hemodialysis (OFID)
• Human monocytotropic ehrlichiosis(PLoS Neglected Tropical Diseases)
• Human granulocytotropic anaplasmosis (PLoS Neglected Tropical Diseases)
• Bifidobacterium and Lactobacillus Probiotics for Preterm Infants (JAMA Network: JAMA Pediatrics)
• Rapid Implementation of Blood Culture Stewardship (CID)
• BD BACTEC Blood Culture Bottle Shortage - (IDSA)
• Fungal
• The Last of US Season 2 (YouTube)
• Clinical characteristics and mortality risks among critically ill patients with culture-proven coccidioidomycosis(OFID)
• Poor Clinical and Microbiologic Outcomes in C. auris Bloodstream Infection (CID)
• Parasitic
• Soap is lethal for Schistosoma mansoni cercariae (PLoS Neglected Tropical Diseases)
• Treatment of uncomplicated hepatic cystic echinococcosis (Cochrane Library)
• Blood exposure to Babesia microti(Cambridge Core)
• Miscellaneous
• Absence of Cerebrospinal Fluid Pleocytosis in Encephalitis (CID)
• Encephalitis due to Infection with Normocellular Cerebrospinal Fluid (CID)
• Podoconiosis and mental health (PLoS Neglected Tropical Diseases)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #60 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/18/20 – 7/31/24.

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• Olympics
• Swimming in the Seine (NYTimes)
• Viral
• Twice-Yearlylenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women (NEJM)
• Consensus definitions of Cytomegalovirus Infection and Disease in Transplant Patients (CID)
• The recombinant shingles vaccine is associated with lower risk of dementia (Nature Medicine)
• Association of the incidence of postherpetic neuralgia with early treatment intervention of herpes zoster (International Journal of Infectious Diseases)
• Bacterial
• Updated guidelines for antimicrobial resistant gram-negative infections (IDSA)
• Put the Vanc Down, Flip it and Reverse it: Comparison of vancomycin and daptomycin (OFID)
• Durations of antibiotic treatment for acute otitis media and variability in prescribed durations (Journal of Pediatric Infectious Diseases Society)
• Fungal
• Adjunctive single-dose liposomal amphotericin to prevent cryptococcal meningitis in people with human immunodeficiency virus (HIV)–associated cryptococcal antigenemia and low plasma cryptococcal antigen (CrAg) titers(CID)
• Stagonospora cutaneous infection in a kidney transplant recipient: First human case (Transplant Infectious Disease)
• European Study of cerebral aspergillosis treated with Isavuconazole: an EFISG study (CID)
• Parasitic
• Rollout of world’s second malaria vaccine begins in Ivory Coast (Healio)
• Executive summary: Evaluation and management of delusional infestation(CID)
• Parasitic contamination of soil in the Southern United States (ASTMH)
• Miscellaneous
• The potential benefits of delaying seasonal influenza vaccine selections for the northern hemisphere: A retrospective modeling study in the United States (JID)

Music is by Ronald Jenkees

On episode #51 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/13 – 3/27/24.

Hosts: Daniel Griffin and Sara Dong

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• Viral
• The oral antiviral obeldesivir protects NHPs against Sudan ebolavirus (Science)
• Monoclonal antibody therapy to treat Ebola virus disease (Curr Opinion Vir)
• Opinion of anti-Sudan ebolavirus antiviral therapy (Science)
• Management of norovirus in solid organ and hematopoietic stem cell transplants (Transplant ID)
• Bacterial
• Bacteremia from urinary source in hospitalized adults with asymptomatic bacteriuria?(JAMA)
• UTI research reference standards (Lancet Infectious Diseases)
• Aspiration pneumonia (CHEST)
• Household transmission of Strep A (JID)
• Antimicrobial dosing recommendations for obese patients (Antimicrobial Agents and Chemotherapy)
• Syphilis testing (MMWR)
• Predictors of morality from streptococcal bacteremia (CID)
• Fungal
• Invasive candidiasis (Nat Rev Disease Primer)
• Climate change and natural disasters impact on fungal infections (Lancet Microbe)
• Parasitic
• Nasal flushing and Acanthamoeba infection (Emerging Infectious Diseases)
• Miscellaneous
• Vaccination guidelines for adults with cancer (Journal of Clinical Oncology)
• Do multiplexed molecular diagnostic tools impact treatment for children with acute gastroenteritis? (CID)

Music is by Ronald Jenkees

On episode #50 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/28 – 3/12/24.

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• Viral
• Measles….and more measles (JPIDS)
• Need for new mumps vaccine (PIDJ)
• Cabotegravir and rilpivirine for those infected with HIV (JAMA)
• Genetic susceptibility to astrovirus diarrhea (OFID)
• 10 years after hepatitis E vaccination (Lancet)
• Tecovirimat for improvement of mpox symptoms (OFID)
• Bacterial
• Clinical care for tick-borne disease affected by paging clinicians serological results (AJTHM)
• Metabolomics of nontuberculous mycobacterial pulmonary disease (JID)
• Predicting risk of infectious endocarditis in those with Staphylococus aureus bacteraemis (JID)
• Fungal
• Response to invasive pulmonary aspergillosis (OFID)
• Parasitic
• Postsurgical outcomes due to hippocampal sclerosis (AJTHM)
• Miscellaneous
• What does the neutrophil to lymphocyte ratio mean in elderly with severe sepsis and diabetes mellitus (BMC Geriatrics)
• Impact of learning from Febrile podcast for infectious diseases (OFID)

Music is by Ronald Jenkees

On episode #49 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/14 – 2/27/24.

Hosts: Daniel Griffin and Sara Dong

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• Viral
• HIV Cure?  (NEJM)
• The effects of HIV-1 antigen-expanded specific T-Cell therapy and vorinostat on persistent infection (JID)
• The burden of HMPV and influenza associated hospitalizations in adults (JID)
• Bacterial
• Length of antibiotic therapy among the hospitalized with uncomplicated pneumonia (Infection Control & Hospital Epidemiology)
• Guideline on fecal microbiota–vased therapies for some gastrointestinal diseases (Gastroenterology)
• Guideline on fecal microbiota–based therapies for recurrent C diff (CIDRAP)
• Reduced vancomycin susceptibility in Clostridioides difficile (CID)
• Fungal
• Histoplasmosisin non-HIV population (OFID)
• Parasitic
• Plasmodium falciparum under the host’s Immune radar(JID)
• Did you hear Artemether-lumefantrine is recommended for uncomplicate malaria CID)
• Miscellaneous
• Uncompensated work in academic infectious diseases, seriously? (CID)
• Invasive mosquito Anopheles stephensi, Ghana (Emerging Infectious Diseases)

Music is by Ronald Jenkees

On episode #48 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/31 – 2/13/24.

Hosts: Daniel Griffin and Sara Dong

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• Viral
• Infectious attenuated tetravalent Butanatan-Dengue vaccine (NEJM)
• Kids with severe disease following first and second dengue virus infection (Nature)
• Oropouche fever outbreak in Latin America (Lancet Infectious Diseases)
• CMV mRNA vaccine knocks out gB/MF59 vaccine (JID)
• Acyuclovir-resistant mucocutaneous HSV in immunocompromised patients (OFID)
• Bacterial
• Dalbavancin for vertebral osteomyelitis (OFID)
• Severe vibrio vulnificus infections (MMWR)
• Demystifying UTIs in the era of antibiotic resistance (PLoS Pathogens)
• Syphilis testing recommendations (MMWR)
• Doxycycline vs azithromycin for scrub typhus (BMC Infectious Diseases)
• REALLY drug resistant Pseudomonas aeruginosa outbreak(CID)
• Fungal
• SUBA or conventional itraconazole for treatment of endemic mycoses (OFID)
• Fluconazole resistant Candida (CDC)
• Are you in the hospital too long after being treated with echinocandin for your Candidemia or invasive Candidiasis (OFID)
• Nasopharyngeal swab or lower respiratory tract specimen for Pneumocystis jirovecii diagnosis (OFID)
• Global guideline for cryptococcosis diagnosis and management (Lancet Infectious Disease)
• Parasitic
• Toxoplasma IgG positivity associates with increase mortality (AJTMH)
• Miscellaneous
• How well did infectious diseases fellows match (JID)
• Back to the future of the physician-scientist in infectious diseases (JID)
• Full or not infectious disease training (JID)

Music is by Ronald Jenkees

On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/18 – 1/31/24.

Hosts: Daniel Griffin and Sara Dong

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• Viral
• Reinfection by Zika via genome diversity and antibody response (EID-Emerging Infectious Disease)
• People with HIV should breast/chest feed (CID)
• Norovirus GII in the water (PLoS Water)
• Herpes zoster and duloxetine premedication for neuralgia (CID)
• Bacterial
• SABATO: early oral switch trial (Lancet)
• Guideline for concordant antibiotic therapy to treat community-acquired pneumonia (Chest)
• Ceftriaxon with or without Nafcillin/Oxacillin for MSSA treatment (OFID)
• Ceftriaxone to prevent ventilator-associated pneumonia trial (Lancet)
• Azithromycin part of routine well-infant visits (NEJM)
• Burkholderia pseudomallei in Mississippi(NEJM)
• Cefiderocol red wine urine syndrome in children (Pediatric Infectious Disease Journal)
• Fungal
• InsuranceClaims equals blastomycosis Incidence (EID)
• Antimicrobial stewardship for coccidioidomycosis in endemic region (OFID)
• Endemic mycosesafter solid organ transplantation (OFID)
• Parasitic
• Headbobbing trematoda (CMI)
• Miscellaneous
• Suspected hemophagocytic lymphohistiocytosis (JPIDS)
• BioFire FilmArray for real-life assessment of hospitalized respiratory illness (JID)
• Clinical microbiology conferences gender and geography (Lancet)
• Is the toilet really the greatest sanitation invention? (AJICJ)

Music is by Ronald Jenkees

On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/4 – 1/17/24.

Hosts: Daniel Griffin and Sara Dong

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• Comparing the performance of three models incorporating weather data to forecast dengue epidemics (JID)
• Elucidating the impacts of climate on dengue transmission through mathematical models (JID)
• Infants receiving a single dose of nirsevimab to prevent RSV do not have evidence of enhanced disease in their second RSV season (JPIDS)
• Patient perspectives on solid organ transplantation from donors with hepatitis C viremia to recipients without hepatitis C viremia (OFID)
• Oral Beta-Lactams, Fluoroquinolones, or Trimethoprim-Sulfamethoxazole for definitive treatment of uncomplicated Escherichia coli or Klebsiella species bacteremia from a urinary source (OFID)
• Discontinuation of contact precautions for methicillin-resistant Staphylococcus aureus in a pediatric healthcare system (JPIDS)
• Oral linezolid compared with benzathine PCN G for treatment of early syphilis in adults (The Lancet)
• Model-informed precision dosing improves outcomes in patients receiving vancomycin for gram-positive infections (OFID)
• The Xpert MTB/RIF cycle threshold value predicts M.tuberculosis transmission to close contacts (CID)
• Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (The Lancet)
• Oral antibiotics for treatment of Gram negative bacteremia in solid organ transplant recipients (CID)
• Dematiaceous fungal keratitis with tentacles mimicking Pythium Keratitis (Jama)
• Verification, analytical sensitivity, cost-effectiveness, and comparison of four Candida auris screening methods (OFID)
• Tafenoquine-Atovaquone combination achieves radical cure and confers sterile immunity in experimental models of human babesiosis (JID)
• Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID)
• Understanding parental leave policies in ID fellowship (OFID)
• What’s hot this year in ID clinical science (CID)

Music is by Ronald Jenkees

On episode #45 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/20/23 – 1/3/24.

Hosts: Daniel Griffin and Sara Dong

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• Notes coming soon
• Bacterial
• Change in oral PrEP affect kidney function (OFID)
• Preventing STIs in women (NEJM)
• Revising antibiotic and STI trials (NEJM)
• Treatment for pediatric febrile UTIs (Pediatrics)
• Burkholderia pseudomallei in Mississippi (NEJM)
• Acute kidney injury and gentamicin treatment for endocarditis (JACAMR)
• Pacemakers for Lyme disease patients (OFID)
• Pseudomonas aeruginosa update  and must have references (CMI)
• Fungal
• Definining optimal dose liposomal amphotericin B for Candida auris (JID)
• Cryptococcus neoformans and HIV serology (OFID)
• Global emergence of Candida auris (OFID)
• Novel anti-cancer therapeutics and fungal biology (PLoS Pathogens)
• Parasitic
• Second malaria vaccine prequalified (WHO)
• Seasonal vaccination against malaria in children (Lancet ID)
• Toxoplasma gondii treatement guidelines for patients with haematological malignancies (Lancet ID)
• Miscellaneous
• Eye infection review (NEJM)
• Diagnosing children with gastroenteritis using molecular testing (CID)
• Are hospital coffee machines pathogenic (BMJ)
• Putting down the fluoroquinolone (CID)

Music is by Ronald Jenkees

On episode #44 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 12/8 – 12/20/23.

Hosts: Daniel Griffin and Sara Dong

Subscribe (free): Apple Podcasts, RSS, email

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• Mpox and chickenpox co-infection (J Inf Dis)
• Corticosteroids for postherpetic neuralgia (Coch Data Syst Rev)
• Dengue incidence and mortality in Bangladesh (J Inf Dis)
• ACORN trial vancomycin and piperacillin-tazobactam (Open For Inf Dis)
• Models for infection risk in children with cancer (J Clin Oncol)
• Salmonella outbreak from cantaloupes (CDC)
• Pediatric antimicrobial stewardship programs ( Ped Inf Dis Soc)
• MRSA nasal swab PCR assay (J Ped Inf Dis Soc)
• Invasive meningococcal disease (Open For Inf Dis)
• Probiotics for recurrent UTI (Clin Inf Dis)
• Preservation fluid contamination and kidney transplant patients (Transpl Inf Dis)
• Mechanism of zinc prevention of candidiasis (Sci Transl Med)
• Risk factors for invasive fungal infection (Open For Inf Dis)
• Genetic variants associated with S. mansoni worm burden (PLoS NTD)
• Chagas disease GI manifestations (Am J Trop Med Hyg)
• Wolbachia in Aedes aegypti in Colombia (PLoS NTD)

Music is by Ronald Jenkees