Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health – Details, episodes & analysis

In the inaugural episode of the Histamine Well Podcast, Joanne, introduces the nuanced topic of histamine intolerance. Designed for both health practitioners and patients, the episode breaks down the science behind histamine, its role in the body, the widespread issue of chronic inflammation driving up histamine levels, and the symptoms it causes such as skin issues, gastrointestinal problems, anxiety, migraines, insomnia and hormonal imbalances. 

Joanne emphasizes the need for a comprehensive approach to diagnose and treat histamine intolerance through understanding its root causes rather than just following restrictive low-histamine diets. She also shares her journey into understanding histamine and offers insights into making practical and informed decisions for better health.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

Welcome to The Histamine Well with your host, Joanne Kennedy. In this introductory episode, Joanne shares the purpose behind the podcast and what you can expect in future episodes. Whether you’re a practitioner or someone living with chronic health challenges like gut issues, skin problems, hormonal imbalances, fatigue, or food intolerances, this podcast is here to provide clarity and support.

Joanne will break down complex science into easy-to-understand insights, exploring topics such as histamine intolerance, MTHFR, methylation, gut health, mold illness, women’s hormones, and much more. Tune in each week for in-depth episodes and expert interviews, plus case studies that help you navigate your health journey with practical advice, testing options, dietary strategies, supplements, and holistic healing tips.

Subscribe now and join the conversation towards healing and improved health.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

High histamine levels are often a signal of deeper imbalances, and in this episode of The Histamine Well, we’re uncovering the hidden root causes that could be driving your symptoms. From SIBO and gluten intolerance to leaky gut and methylation issues, we’ll explore why histamine intolerance is rarely just about food and how addressing the underlying factors can lead to real, lasting solutions. 

Whether you’re managing your own health, supporting others on their journey as practitioner, this episode will empower you with insights that go far beyond symptom management, helping you get to the “why” behind histamine issues.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well podcast, Joanne delves into the intricate relationship between histamine and oestrogen. She explores how histamine can stimulate excess oestrogen production and vice versa, leading to a range of symptoms such as migraines, dizziness, anxiety, and digestive issues. 

Joanne discusses the impact of factors like methylation, gut health, and enzyme functionality on this dynamic. She provides practical advice on managing these issues, including dietary adjustments and supplementation. 

Joanne also highlights the role of perimenopause in exacerbating histamine-oestrogen interactions and offers strategies for hormonal balance. Listeners are encouraged to explore deeper through additional episodes and resources.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well podcast, Joanne is joined by her colleague, Melanie Peers, an expert in oxalate issues. Together they explore the complex world of oxalates, their profound impact on histamine intolerance, methylation pathways, and overall health. 

They discuss how oxalates drive chronic inflammation, deplete sulfur levels, and disrupt both the methylation and transsulfuration pathways, causing low homocysteine levels.

The discussion also covers the extensive symptoms associated with oxalate toxicity, common high-oxalate foods, and the often-overlooked impact of mold on oxalate levels. 

They also offer valuable insights for practitioners and patients on tackling oxalate-related issues, addressing nervous system dysfunction, and the importance of a holistic approach to health. Whether you’re a health professional or navigating your personal wellness journey, this episode is packed with essential information and actionable advice.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne is joined by naturopath Bridget Greenall to discuss Small Intestinal Bacterial Overgrowth (SIBO), particularly focusing on how to diagnose and treat it without testing. 

They explore the intertwined issues of SIBO, inflammation, and blood sugar dysregulation and their impact on hormonal health, including PMS and hot flushes. 

The conversation provides practical insights for practitioners, students, and patients on managing SIBO, especially under financial or geographical constraints that prevent testing. 

Additionally, they touch upon the significance of methylation in addressing hormonal imbalances and introduce an at-home saliva methylation test. 

The episode wraps up with detailed case studies, addressing facets of SIBO treatment and related hormonal symptoms.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well, Joanne breaks down the complexities of multiple food intolerances.

She explains how SIBO and oxalates can drive up histamine, leading to oxalate, histamine, and FODMAP intolerances.

Oxalates also deplete sulfur. This can cause an overgrowth of sulfur-producing bacteria in the gut, triggering sulfur intolerance. A lack of sulfur can also contribute to salicylate intolerance.

Joanne explores the link between nervous system dysfunction and food intolerances, showing how they are deeply connected.

She also shares how to prioritize which intolerances to address first. Plus, she covers the importance of testing to uncover the root causes.

Tune in to learn more!

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, Joanne dives deep into the topic of MTHFR, an enzyme crucial for the process of methylation. Joanne explains the significance of methylation in various biochemical and genetic processes such as detoxification, neurotransmitter regulation, and genetic expression. The episode also addresses why methylfolate is essential, discusses common causes of methylfolate deficiency, and highlights why folic acid can be problematic for everyone.

Joanne provides insights into various types of folate testing and offers practical guidance for those with MTHFR mutations and other related conditions. This comprehensive episode is designed to provide actionable knowledge for both practitioners and individuals on their wellness journey.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well, Joanne is joined by scientist James Bradshaw to discuss the complexities of methylation and its critical role in genetics, mood, and overall health. 

James shares his extensive background in biochemistry and cellular biology and introduces Mood Sense, the first saliva test for assessing methylation-related mood disruptions. 

They explore the essentials of methylation, its impact on neurotransmitter production, and the difference between over and under methylation. 

The episode also delves into genetic mutations, environmental factors affecting methylation, and practical approaches to managing methylation in clinical practice. 

Listeners gain insights into the role of methylation in various chronic health conditions and how personalized testing can lead to better health outcomes.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well podcast, Joanne dives into the connection between methylation, detoxification, and gallbladder health. Joined by nutritionist Olivia Haas, they discuss how impaired methylation affects bile flow, leading to gallbladder dysfunction and increased histamines. 

Olivia explains the essential role of the gallbladder in digestion, detoxification, and overall health. They cover early warning signs of gallbladder issues, appropriate testing, and the interplay between estrogen dominance, mold, and oxalate sensitivities. Practical recommendations for dietary and supplement support for gallbladder and liver health, both pre- and post-surgery, are also discussed. 

Olivia also speaks about her specialized programs and memberships designed to assist patients with gallbladder concerns. 

This episode is packed with insights and actionable advice for both practitioners and patients.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!