Saving Lives Podcast: Critical Care w/eddyjoemd – Details, episodes & analysis

In this episode of the Saving Lives Podcast, we dive into the DecatSepsis trial, exploring the role of dexmedetomidine in reducing mortality and managing septic shock. Discover how this sedative could help mitigate the harmful effects of the hyperadrenergic state in septic patients.

The Vasopressor & Inotrope Handbook I have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy. Amazon: ⁠⁠https://amzn.to/47qJZe1⁠⁠ (Affiliate Link) Signed & Personalized Copy: ⁠⁠https://eddyjoemd.myshopify.com/products/the-vasopressor-inotrope-handbook⁠⁠ My website: ⁠⁠www.eddyjoemd.com⁠⁠ Instagram: ⁠⁠www.instagram.com/eddyjoemd⁠⁠ X: ⁠⁠www.x.com/eddyjoemd⁠⁠ Facebook: ⁠⁠www.facebook.com/eddyjoemd⁠⁠ My Amazon store for resources you may find helpful: ⁠⁠www.amazon.com/shop/eddyjoemd⁠⁠ @eddyjoemd is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com Although great care has been taken to ensure that the information in this podcast is accurate, eddyjoemd, LLC shall not be held responsible or liable for its continued accuracy or any errors, omissions, inaccuracies, or consequences arising from it.

Citation

Ezz Al-Regal AR, Ramzy EA, Allah Atia AA, Emara MM. Dexmedetomidine for Reducing Mortality in Patients With Septic Shock A Randomized Controlled Trial (DecatSepsis). Chest. 2024 Jul 14:S0012-3692(24)04601-4. doi: 10.1016/j.chest.2024.06.3794. Epub ahead of print. PMID: 39004217.

In this episode of the Saving Lives Podcast, we discuss a recent randomized controlled trial exploring the use of minocycline to prevent delirium in critically ill patients. The study reveals that minocycline may significantly reduce delirium incidence and hospital mortality, offering a promising new pharmacologic approach.

The Vasopressor & Inotrope Handbook I have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy. Amazon: ⁠⁠https://amzn.to/47qJZe1⁠⁠ (Affiliate Link) Signed & Personalized Copy: ⁠⁠https://eddyjoemd.myshopify.com/products/the-vasopressor-inotrope-handbook⁠⁠ My website: ⁠⁠www.eddyjoemd.com⁠⁠ Instagram: ⁠⁠www.instagram.com/eddyjoemd⁠⁠ X: ⁠⁠www.x.com/eddyjoemd⁠⁠ Facebook: ⁠⁠www.facebook.com/eddyjoemd⁠⁠ My Amazon store for resources you may find helpful: ⁠⁠www.amazon.com/shop/eddyjoemd⁠⁠ @eddyjoemd is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com Although great care has been taken to ensure that the information in this podcast is accurate, eddyjoemd, LLC shall not be held responsible or liable for its continued accuracy or any errors, omissions, inaccuracies, or consequences arising from it.

Citation

Dal-Pizzol F, Coelho A, Simon CS, Michels M, Corneo E, Jeremias A, Damásio D, Ritter C. Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial. Chest. 2024 May;165(5):1129-1138. doi: 10.1016/j.chest.2023.11.041. Epub 2023 Dec 1. PMID: 38043911.

In this episode of The Saving Lives Podcast, we explore the innovative MitraClip system, a less invasive treatment for mitral regurgitation. The discussion covers the device's evolution, its impact on patient outcomes, and the challenges and complications associated with its use.

The Vasopressor & Inotrope Handbook I have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy. Amazon: ⁠⁠https://amzn.to/47qJZe1⁠⁠ (Affiliate Link) Signed & Personalized Copy: ⁠⁠https://eddyjoemd.myshopify.com/products/the-vasopressor-inotrope-handbook⁠⁠ My website: ⁠⁠www.eddyjoemd.com⁠⁠ Instagram: ⁠⁠www.instagram.com/eddyjoemd⁠⁠ X: ⁠⁠www.x.com/eddyjoemd⁠⁠ Facebook: ⁠⁠www.facebook.com/eddyjoemd⁠⁠ My Amazon store for resources you may find helpful: ⁠⁠www.amazon.com/shop/eddyjoemd⁠⁠ @eddyjoemd is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com Although great care has been taken to ensure that the information in this podcast is accurate, eddyjoemd, LLC shall not be held responsible or liable for its continued accuracy or any errors, omissions, inaccuracies, or consequences arising from it.

Citation: Schnitzler K, Hell M, Geyer M, Kreidel F, Münzel T, von Bardeleben RS. Complications Following MitraClip Implantation. Curr Cardiol Rep. 2021 Aug 13;23(9):131. doi: 10.1007/s11886-021-01553-9. PMID: 34387748; PMCID: PMC8363549.

Could a CBC w/diff tell us who's going to do poorly with COVID? Using the neutrophil to lymphocyte ratio could be quite helpful.

Show Notes: www.eddyjoemd.com/NLR

Receive a FREE audiobook (TWO for Amazon Prime members) with your FREE 30-day trial by using my link for Audible: CLICK HERE! You will be reminded when your trial is ending, by the way. 😉

Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

Website: www.eddyjoemd.com
Instagram: www.instagram.com/eddyjoemd
Twitter: www.twitter.com/eddyjoemd
Facebook: www.facebook.com/eddyjoemd
Podcast: https://anchor.fm/eddyjoemd
My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd 

Citation: Li, X., Liu, C., Mao, Z. et al. Predictive values of neutrophil-to-lymphocyte ratio on disease severity and mortality in COVID-19 patients: a systematic review and meta-analysis. Crit Care 24, 647 (2020). https://doi.org/10.1186/s13054-020-03374-8

Looking into which fluids we should use to resuscitate our patients who are in Diabetic Ketoacidosis based on the findings of the SALT-ED and SMART trials.

Show Notes: www.eddyjoemd.com/ivf-guide

Receive a FREE audiobook (TWO for Amazon Prime members) with your FREE 30-day trial by using my link for Audible: CLICK HERE! You will be reminded when your trial is ending, by the way. 😉

Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

My website: www.eddyjoemd.com
Instagram: www.instagram.com/eddyjoemd
Twitter: www.twitter.com/eddyjoemd
Facebook: www.facebook.com/eddyjoemd
Podcast: https://anchor.fm/eddyjoemd
My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd

Citation: Self WH, Evans CS, Jenkins CA, Brown RM, Casey JD, Collins SP, Coston TD, Felbinger M, Flemmons LN, Hellervik SM, Lindsell CJ, Liu D, McCoin NS, Niswender KD, Slovis CM, Stollings JL, Wang L, Rice TW, Semler MW; Pragmatic Critical Care Research Group. Clinical Effects of Balanced Crystalloids vs Saline in Adults With Diabetic Ketoacidosis: A Subgroup Analysis of Cluster Randomized Clinical Trials. JAMA Netw Open. 2020 Nov 2;3(11):e2024596. doi: 10.1001/jamanetworkopen.2020.24596. PMID: 33196806.

The ROX index is defined as the ratio of oxygen saturation as measured by pulse oximetry (SpO2)/FIO2 to respiratory rate (RR). It stands for Respiratory rate - OXygenation. ROX ≥ 4.88 at 2, 6, and 12 hours means they're likely in the safe zone. ROX < 2.85 at 2 hours, ROX < 3.47 at 6 hours, ROX < 3.85 at 12 hours means the patient likely needs to be intubated. 

Show Notes: www.eddyjoemd.com/rox

Receive a FREE audiobook (TWO for Amazon Prime members) with your FREE 30-day trial by using my link for Audible: CLICK HERE! You will be reminded when your trial is ending, by the way. 😉

Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

My website: www.eddyjoemd.com
Instagram: www.instagram.com/eddyjoemd
Twitter: www.twitter.com/eddyjoemd
Facebook: www.facebook.com/eddyjoemd
Podcast: https://anchor.fm/eddyjoemd
My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd

Fluvoxamine is an SSRI that may improve outcomes in COVID-19 when administered in the outpatient setting. This small trial published in JAMA two days ago looks into the positive effects of this therapy to prevent clinical worsening of patients with COVID.

Show Notes: https://eddyjoemd.com/fluvoxamine

Receive a FREE audiobook (TWO for Amazon Prime members) with your FREE 30-day trial by using my link for Audible: CLICK HERE! You will be reminded when your trial is ending, by the way. 😉

Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

My website: www.eddyjoemd.com
Instagram: www.instagram.com/eddyjoemd
Twitter: www.twitter.com/eddyjoemd
Facebook: www.facebook.com/eddyjoemd
Podcast: https://anchor.fm/eddyjoemd
My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd

Citation: Lenze EJ, Mattar C, Zorumski CF, Stevens A, Schweiger J, Nicol GE, Miller JP, Yang L, Yingling M, Avidan MS, Reiersen AM. Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Randomized Clinical Trial. JAMA. 2020 Nov 12. doi: 10.1001/jama.2020.22760. Epub ahead of print. PMID: 33180097.

Could Aspirin 81mg in COVID-19 patients help keep them off of mechanical ventilation, out of the ICU, and decrease mortality? Let's explore!

Show Notes: https://eddyjoemd.com/aspirin-covid/

Receive a FREE audiobook (TWO for Amazon Prime members) with your FREE 30-day trial by using my link for Audible: CLICK HERE! You will be reminded when your trial is ending, by the way. 😉

Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

My website: www.eddyjoemd.com
Instagram: www.instagram.com/eddyjoemd
Twitter: www.twitter.com/eddyjoemd
Facebook: www.facebook.com/eddyjoemd
Podcast: https://anchor.fm/eddyjoemd
My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd

Citation: Chow JH, Khanna AK, Kethireddy S, Yamane D, Levine A, Jackson AM, McCurdy MT, Tabatabai A, Kumar G, Park P, Benjenk I, Menaker J, Ahmed N, Glidewell E, Presutto E, Cain S, Haridasa N, Field W, Fowler JG, Trinh D, Johnson KN, Kaur A, Lee A, Sebastian K, Ulrich A, Peña S, Carpenter R, Sudhakar S, Uppal P, Fedeles BT, Sachs A, Dahbour L, Teeter W, Tanaka K, Galvagno SM, Herr DL, Scalea TM, Mazzeffi MA. Aspirin Use is Associated with Decreased Mechanical Ventilation, ICU Admission, and In-Hospital Mortality in Hospitalized Patients with COVID-19. Anesth Analg. 2020 Oct 21. doi: 10.1213/ANE.0000000000005292. Epub ahead of print. PMID: 33093359.

Do COVID-19 patients who suffer a cardiac arrest in the hospital survive? Should we even attempt CPR on these COVID patients? We should.

Show Notes: https://eddyjoemd.com/cardiac-arrest-covid/ 

Receive a FREE audiobook (TWO for Amazon Prime members) with your FREE 30-day trial by using my link for Audible: CLICK HERE! You will be reminded when your trial is ending, by the way. 😉

Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

My website: www.eddyjoemd.com
Instagram: www.instagram.com/eddyjoemd
Twitter: www.twitter.com/eddyjoemd
Facebook: www.facebook.com/eddyjoemd
Podcast: https://anchor.fm/eddyjoemd
My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd

Citation: Shah, Priyank MD, MPH, FACC1; Smith, Hallie ABJ, MS; Olarewaju, Ayodeji MD; Jani, Yash MS; Cobb, Abigail MSN, FNP; Owens, Jack MD, MPH; Moore, Justin MPH, PhD; Chenna, Avantika MD; Hess, David MD. Is Cardiopulmonary Resuscitation Futile in Coronavirus Disease 2019 Patients Experiencing In-Hospital Cardiac Arrest?, Critical Care Medicine: October 21, 2020 - Volume Online First - Issue - doi: 10.1097/CCM.0000000000004736

Criticalcarereviews.com

Criticalcarenow.com

Receive a FREE audiobook (TWO for Amazon Prime members) with your FREE 30-day trial by using my link for Audible: CLICK HERE! You will be reminded when your trial is ending, by the way. 😉

Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

My website: www.eddyjoemd.com
Instagram: www.instagram.com/eddyjoemd
Twitter: www.twitter.com/eddyjoemd
Facebook: www.facebook.com/eddyjoemd
Podcast: https://anchor.fm/eddyjoemd
My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd