Parkinson's Disease Podcasts by No Silver Bullet – Details, episodes & analysis

We are delighted to be able to share with you our latest interview with 
Dr Filip Scheperjans who shared with us his fantastic work on "The importance of the gut-brain axis in Parkinson's" which was followed by an excellent Q & A session. 

More about our expert:-

Dr. Filip Scheperjans is a leading expert in neurology, specialising in treating Parkinson’s disease and focusing on advanced methods and gastrointestinal symptoms.

He earned his Licentiate of Medicine from the University of Düsseldorf in 2006 and completed his Neurology specialisation at the University of Helsinki in 2013. In 2008, he received his Doctor of Medical Science, focusing on neuroanatomy, and became Associate Professor in 2020 at the University of Helsinki.

Dr. Scheperjans investigates the relationship between gastrointestinal symptoms and the microbiome in Parkinson’s disease, exploring novel treatment strategies. His work includes advanced therapies like drug infusions and deep-brain stimulation, supported by major organisations such as the Academy of Finland and the Michael J. Fox Foundation.

Prof Sonia Gandhi joined us to share her expertise on how Mitochondria affects PD with an excellent presentation followed by a very probing Q&A by our well informed audience.

Prof Gandhi is a leading expert in the process of protein misfolding, in which smaller proteins, monomers, join together to form larger proteins, oligomers, and how this process may drive organellar dysfunction and cell toxicity in neurodegeneration.

Sonia obtained a BA in Neuroscience at Trinity College, University of Cambridge, in 1996, and completed her degree in Medicine at New College, University of Oxford, in 1999. She trained in postgraduate medicine at the Hammersmith Hospital, Royal Brompton Hospital, National Hospital for Neurology and Neurosurgery, and Whittington Hospital. 
Sonia was awarded a Wellcome Clinical Research Training Fellowship to complete a PhD in Neuroscience at UCL Institute of Neurology in 2004. In 2007, she trained as a Specialist registrar in Neurology, and took up an NIHR Lectureship in Neurology at Imperial College in 2009. In 2012 she was awarded a Wellcome Trust Intermediate Clinical Fellowship, and established her laboratory at the UCL Institute of Neurology in October 2013. She was awarded a laboratory secondment to the Francis Crick Institute in 2016

Some of the most promising disease modifying therapies being developed at the moment are based on drug repurposing (eg Exenatide/Ambroxol), making this webinar essential for anyone suffering from Parkinson's or caring for someone suffering from Parkinson's.

Dr Lorraine Kalia shares with us her expertise and brings us up to date with the latest news.

Dr. Lorraine Kalia is an associate professor and a clinician-scientist at the University of Toronto in Canada. She is dedicated to Parkinson's disease, both in her clinical practice as a movement disorders neurologist and in her research program as a neuroscientist.

She is the co-editor-in-chief of the Journal of Parkinson’s Disease and co-chair of the International Parkinson and Movement Disorder Society Scientific Issues Committee.

Her research focuses on understanding the fundamental molecular processes that lead to neurodegeneration in Parkinson’s disease and finding new therapies that can target these molecular culprits to slow down or even stop the disease.

Dr. Kalia recently presented at the World Parkinson's Congress in Barcelona.

More can be found out about the speaker here:-

https://lmp.utoronto.ca/faculty/lorra...

Website https://kalialabs.org/

To find out the latest trails if you are based in or around Toronto Email lorraine.kalia@utoronto.ca

We are delighted to welcome back the CEO and Founder of Charconeurotech to tell us more about the CUE1 device to help with Parkinson's symptoms

Charco Neurotech, the company behind CUE1, was founded by CEO Lucy Jung and named after Professor Charcot, who discovered the therapeutic effects of vibratory stimulation on Parkinson's in the 19th century. Since then, numerous studies have been conducted on the ability of stimulation to alleviate movement symptoms associated with the disease.

CUE1 combines the principles of focussed vibrotactile stimulation and cueing, both of which have been scientifically proven to improve motor performance and reduce freezing of gait in people with Parkinson's. The company's testing has demonstrated clinically significant improvements in motor symptoms, including smoother walking and movement, and better fine motor task performance.

https://charconeurotech.com/

CUE1 combines the principles of focussed vibrotactile stimulation and cueing, both of which have been scientifically proven to improve motor performance and reduce freezing of gait in people with Parkinson's. The company's testing has demonstrated clinically significant improvements in motor symptoms, including smoother walking and movement, and better fine motor task performance.
CUE1 is already being used by around 1,000 people in the UK and Addenbrooke's Hospital in Cambridge, UK, has recently begun trialling the device with its inpatients, as reported in this news article:

https://www.cuh.nhs.uk/news/high-tech...

To add your name to the waiting list use this link:- https://charconeurotech.com/register-...

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Dr. Peter Tass from Stanford Medical School talks to us about “The Parkinson's glove & Vibrotactile fingertip stimulation to ease Parkinson’s symptoms”. A very very interesting device currently being trialed in the USA, with huge potential to dramatically improve the lives of many with PD

About the Speaker:-

Peter Tass studied medicine (MD, Ulm and Heidelberg Univ., Germany), physics (PhD, Stuttgart Univ., Germany), and mathematics (diploma, Stuttgart Univ.) and made a Habilitation in physiology (RWTH Aachen University, Germany).

Since 2017 he is Professor of Neurosurgery in the Department of Neurosurgery, Stanford University Medical School. Peter Tass investigates and develops neuromodulation techniques for understanding and treating neurologic conditions such as Parkinson’s disease, epilepsy, dysfunction following stroke and tinnitus. He creates invasive and non-invasive therapeutic procedures by means of comprehensive computational neuroscience studies and advanced data analysis techniques.

Peter Tass has published more than 170 peer-reviewed papers, is inventor or co-inventor on more than 270 patents and received a number of national and international awards.

Stanford lab homepage: https://med.stanford.edu/tass-lab.html

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If you want to know where to start in addressing your PD symptoms then this is the place and the video to start with.

Dr. Mischley gives us a roadmap to what successful people do, linking topics that many of our previous world-leading speakers have spoken to us about before.

Much of the session focuses on The Parkinson Symptom Tracker (PRO-PD App) designed as a tool for assessing and tracking symptom severity over time. It is freely available on the iOS and Android app stores.

For more information: see https://pd-symptoms.com/ and watch this video by Dr. Mischley https://www.youtube.com/watch?v=5tx8rNBWx4M

If you are interested in participating in research (~ 3 hours per year answering online questions), please consider participating in the ongoing Modifiable Variables in Parkinsonism Study: https://mvp-study.com/

About the speaker:-

Dr. Laurie Mischley is a naturopathic physician and researcher specialising in the treatment and management of Parkinson's disease (PD). With over 20 years of experience in the field, she has become a leading expert in the use of natural therapies for PD.

Dr. Mischley studied naturopathic medicine (ND) at Bastyr University and epidemiology (MPH) and nutritional sciences (PhD) at the University of Washington. Her work is focused on identifying the nutritional requirements unique to individuals with PD. She has published on coenzyme Q10, lithium, glutathione and mitochondrial deficiency in PD. She is Principal Investigator of the Modifiable Variables in Parkinsonism Study (mvp-study.com), which is attempting to describe why some people with PD progress slower than others.

Dr. Mischley is working on ways to study, package and deliver evidence-based lifestyle modification as a therapeutic strategy. She founded the canine scent-based PD screening tool, ParK-9, developed a patient-reported outcome measure to assess PD severity (PRO-PD) and is instructor of the online series Parkinson School: https://pd-school.teachable.com/

Dr. Mischley maintains a small clinical practice at Seattle Integrative Medicine focused on nutrition and neurological health.

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We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwP

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We are all becoming very aware of the huge benefits of exercise with PD but where do you start and what do you need to do?

Julie Jones is a very experienced physiotherapist with a specialist interest in Parkinson’s and so is perfectly qualified to guide PwP to get more active and feel the benefits of exercise. This is an excellent and natural follow-up to the presentation by Prof Bas Bloem, also available on this channel and highly recommended if you have not watched it.

If you would like a copy of Julie's slides then please email us at nosilverbullet4pd@gmail.com

Julie is a clinical academic fellow, jointly funded by Parkinson’s UK and the Chief Scientist Office and is a senior lecturer at Robert Gordon University. She is also a member of the Strategy Advisory board of Parkinson’s UK in Scotland and chairs the Scotland wide Parkinson’s Active project. She is also a member of the Parkinson’s UK College of Experts grant review panel, and sits on the Research Participation Steering Group at Parkinson’s UK. Within the Parkinson’s Excellence Network, Julie is the co-lead of the Exercise hub, which runs education events to support exercise professionals nationally to improve and develop service provision for people with Parkinson’s.

Julie’s current role spans research, clinical and academic. Julie is currently funded to explore the feasibility and acceptability of a multicomponent intervention designed to support physical activity participation among people with Parkinson’s. Julie has an honorary physiotherapy position within NHS Grampian, and her main clinical interests include exercise and gait dysfunction.

Julie can be contacted:-
The Robert Gordon University  email j.c.jones@rgu.ac.uk

Julie was the keynote speaker in 2022 at The Edinburgh Parkinson's Lecture
   • Edinburgh Parkins... 

IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD.

We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwP

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We are delighted to bring you Dr. Rick Helmich on the topic of "Managing stress with Parkinson's"

Dr. Rick Helmich was recommended to us by Prof Bas Bloem, who considers Rick to be the leading authority in this field. Rick will be discussing stress (both acute and chronic) and the effect that this has on people with Parkinson's disease.

Rick's passion is to understand the cerebral mechanisms that lead to neurological diseases and use these insights to develop new therapies for patients with movement disorders. Rick works as a neurologist and associate professor specialising in Parkinson’s disease and tremor disorders at the Radboud University Medical Centre (with Prof Bas Bloem) and at the Donders Institute, both in the Netherlands.

Rick is very much inspired by clinical observations in patients and uses neuroimaging and neurophysiology to understand the underlying mechanisms. He is particularly intrigued by the profound effects of psychological stress on many neurological movement disorders, by the way patients can compensate for brain dysfunction, and by the different ways in which tremor can manifest itself.

Rick discusses:-
1) What is stress?
2) Can stress cause Parkinson's?
3) How does stress influence Parkinson's?
4)What can we do about it?

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Dear Friend, 

We are thrilled to announce the launch of a new YOPN Podcast, featuring an inspiring story about two of our very own co-founders of NoSilverBullet4PD, Michel Planquart and Mark Limebear. 

Through this podcast, you can discover how their friendship and shared experience of living with Parkinson's disease led them to create a community of support and understanding for those living with the condition. 

Whether you are living with Parkinson's disease, or know someone who is, this podcast is for you. Listen in and learn how their story of resilience and hope has made a profound impact on so many lives. It's a powerful reminder of the strength that comes when people come together and support each other. 

YOPN is Young-onset Parkinson's Network https://www.yopnetwork.org/

Please share, thank you

Listen to this excellent presentation with a very good Q&A at the end, of Dr. Matthew Phillips exploring the potential therapeutic benefits of metabolic strategies, particularly fasting and ketogenic diets, in neurological disorders.

Matt is a clinical and research neurologist at Waikato Hospital, Hamilton, New Zealand. His foremost passion is to explore the potential feasibility, safety, and efficacy of metabolic strategies, particularly fasting and ketogenic diets, in creating alternate metabolic states that may benefit people with a variety of neurological disorders. His team conducted the world’s first randomized studies involving only people with Parkinson’s, followed by Alzheimer’s.

Further resources:-
Metabolic Strategies in Healthcare paper
https://www.ncbi.nlm.nih.gov/pmc/arti...
Parkinson's RCT
https://movementdisorders.onlinelibra...
Metabolic Plan (click Resources)
https://www.metabolicneurologist.com/

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