Struggling with chronic Lyme disease and not getting answers from conventional medicine?
Integrative Lyme Solutions with Dr. Michael Karlfeldt explores evidence-based, integrative approaches to chronic Lyme disease, tick-borne illness, and co-infections — including Bartonella, Babesia, and Ehrlichia — through expert interviews and real patient recovery stories.
Lyme disease is known as the "great imitator" because its symptoms overlap with dozens of complex conditions, including Chronic Fatigue Syndrome (ME/CFS), fibromyalgia, autoimmune disorders, Multiple Sclerosis, and Parkinson's disease. Many patients spend years misdiagnosed or dismissed after false-negative Western blot results. This podcast cuts through the confusion with practical insights on functional medicine, herbal antimicrobials, detoxification, immune support, nervous system healing, and other integrative therapies that support long-term recovery.
With over 35 years of clinical experience, Dr. Karlfeldt brings the knowledge of a Lyme literate naturopathic doctor to every episode — helping patients and caregivers reduce their research time, ask better questions, and find a path forward.
Site
RSS
Apple
Data updated on 16/10/2026
Recent rankings
Latest chart positions across Apple Podcasts and Spotify rankings.
Shared links between episodes and podcasts
Links found in episode descriptions and other podcasts that share them.
Dr. Marie Matheson | Mold, Lyme Disease and Microdosing GLP-1 for Chronic Illness
Episode 257
Monday, October 12, 2026 • Duration 35:29
What if the reason your Lyme treatment stopped working has nothing to do with Lyme at all?
In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Marie Matheson, a naturopathic doctor and co-founder of BioHeal Ottawa, who has spent twenty years treating complex chronic illness. Dr. Matheson traces her path back to a tick bite in her own family, and to the moment, a decade into treating Lyme disease, when she realized a stuck subset of her patients were not failing to improve because of Lyme. They were living with mold.
She explains why she now estimates 80 to 90 percent of her Lyme patients are also dealing with mold toxicity, and why treating the mold often has to come before Lyme treatment can work at all. The conversation moves into microdosing tirzepatide, a GLP-1 GIP peptide she prescribes at a fraction of the standard weight loss dose to calm mast cell activation, joint pain and brain inflammation in her chronic illness patients, along with the detox precautions she builds in when a patient starts losing weight quickly on a GLP-1. If you have been stuck in Lyme disease treatment with no clear answer for why you are not improving, this conversation gives you a place to look you may not have considered.
Key Takeaways:
Why Dr. Matheson now believes 80 to 90 percent of her Lyme disease patients are also dealing with hidden mold toxicity
Microdosing tirzepatide, a GLP-1 GIP peptide, for mast cell activation, joint pain and brain inflammation in Lyme patients
The Goldilocks dose: why 0.33 to 2 milligrams of a GLP-1 outperforms standard weight loss doses for complex chronic illness
Why fat tissue stores toxins, and the liver detox and drainage protocol needed before rapid weight loss on a GLP-1
Why Dr. Matheson starts empirical treatment for Lyme and Babesia before lab results even come back
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Dr. Richard Horowitz | Lyme, Alzheimer's and the 16 Hidden Causes of Chronic Illness
Episode 254
Monday, October 5, 2026 • Duration 46:57
What if the chronic fatigue, brain fog, or unexplained pain you've been living with for years traces back to something your doctor never tested for?
In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Richard Horowitz, a physician who has treated over 13,000 chronically ill patients across four decades, to talk about his new book, Ending Chronic Illness. Dr. Horowitz breaks down the 16-point MSIDS model, a framework connecting chronic Lyme disease to Alzheimer's, autoimmune conditions, long COVID, ADHD, and dozens of other diagnoses through a single shared driver: chronic inflammation. He shares how patients written off by conventional medicine walked, talked, and thought clearly again once the real source of their illness was identified.
This conversation covers the Dapsone protocol for biofilm-forming Lyme bacteria, a groundbreaking case reversing an Alzheimer's biomarker by 63 percent, and why Dr. Horowitz believes the current one-disease, one-drug model is failing patients with complex chronic illness. If you or someone you love has been chasing answers without success, this episode offers a new way to look at the problem.
Key Takeaways:
0:00 Introduction
2:01 Why Dr. Horowitz wrote Ending Chronic Illness
9:15 The 16-point MSIDS model explained
10:54 The wheelchair patient who turned out to have babesia
24:48 Reversing an Alzheimer's biomarker by 63 percent in nine weeks
32:24 Inside the Dapsone protocol and required testing
38:00 Free resources: the Medical Detective Substack and Lyme questionnaire
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Dr. Tom Cowan | Lyme Disease, Antibody Testing and the Contagion Myth
Episode 256
Monday, September 14, 2026 • Duration 45:52
What if the test that diagnosed your Lyme disease, and the theory behind it, was never actually proven in the first place?
In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Thomas Cowan, a physician and author of The Contagion Myth, for a conversation that questions one of the most basic assumptions in the Lyme disease world: that borrelia has actually been shown to cause the illness. Dr. Cowan spent years as an ER doctor before turning his attention to what he calls the unexamined foundations of modern medicine, and in this conversation he walks through why he believes the original Lyme research, the antibody tests built on it, and even the concept of an immune system itself don't hold up to the kind of scrutiny any other medical claim would require.
They get into the 1980s study that first linked spirochetes to Lyme disease, why Dr. Cowan says antibody tests can't be trusted to identify anything specific, and what he does instead when a patient walks in exhausted, in pain, and carrying a diagnosis that hasn't made them any better. If you've ever been told you have chronic Lyme disease and felt like the label explained less than it promised, this conversation offers a different way to think about what's actually happening in your body.
Key Takeaways:
Why Dr. Thomas Cowan argues the original Lyme disease study never proved borrelia causes the illness
The case against Lyme antibody testing: why a positive IgG or IgM result may not mean what patients are told it means
Why long-term antibiotic use, not lingering infection, may explain chronic Lyme disease symptoms for some patients
Dr. Cowan's approach to chronic illness: treating a patient's health history instead of the Lyme disease label
Why there is no clinical definition of Lyme disease, and what that means for anyone diagnosing themselves off a bullseye rash or brain fog
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Linda Fraas | Fibromyalgia Symptoms, Root Causes & Natural Pain Management Without Medication
Episode 255
Monday, August 24, 2026 • Duration 29:35
What if the fatigue, pain, and brain fog you have been told is just stress or aging actually has a name, and a path forward? In this episode of Integrative Lyme Solutions, Dr. K sits down with Linda Fraas, a former occupational therapist turned certified fibromyalgia health coach, who was diagnosed with fibromyalgia herself after nearly 30 years of treating patients with chronic conditions. Linda shares what it actually felt like to be dismissed by a physical therapist who told her the pain was all in her head, and how she went from carrying heavy equipment through daily flare ups to walking two and a half miles several times a week on zero fibromyalgia medication.
The conversation breaks down what fibromyalgia is, why it is still so hard to diagnose, and the tools that helped Linda reclaim her life: energy conservation, sleep hygiene, an anti-inflammatory diet, gentle daily movement, and a functional medicine approach that looks past a normal blood panel to catch what is actually driving the flare ups. If you or someone you love has been told there is nothing more that can be done for their pain, this episode offers a different way forward.
Key Takeaways:
0:00 Introduction
1:11 From occupational therapist to living with fibromyalgia herself
3:29 What fibromyalgia actually is and why it is so hard to diagnose
6:34 A physical therapist told her the pain was all in her head
8:43 The phone battery analogy for a fibromyalgia flare up
14:27 The diet and movement changes that got her off all medication
25:54 Why functional medicine digs deeper than a normal blood panel
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Mo Pritzker | How She Reversed Lyme Disease Using Neuroplasticity, Not Antibiotics
Episode 253
Monday, August 10, 2026 • Duration 37:45
What if the missing piece in your Lyme recovery isn't another antibiotic protocol, but your brain itself?
In this episode of Integrative Lyme Solutions, Dr. K sits down with Mo Pritzker, Co-Founder of re-origin, who spent two years cycling through doctors and alternative treatments for Lyme disease before finally getting better, only to relapse even harder. It wasn't until a doctor handed her a book on neuroplasticity that everything shifted. Mo shares how brain retraining calmed her dysregulated limbic system, helped her body return to homeostasis, and led to being Lyme free for ten years, including a Lyme test that eventually came back negative.
This conversation goes beyond killing the pathogen and into what actually keeps people stuck: a nervous system stuck in survival mode. Mo breaks down the "pause" technique she uses to interrupt negative thought loops, why healing chronic illness is as much a crisis of the whole person as it is a physical one, and why community and coaching were just as critical to her recovery as any protocol. If you're navigating Lyme disease and feel like you've tried everything, this episode offers a piece of the puzzle you may not have considered yet.
Key Takeaways:
0:00 Introduction
1:11 From serial entrepreneur to sudden health collapse
3:07 The perfect storm that broke her body down
9:20 A doctor handed her a book that changed everything
11:24 Why neuroplasticity worked when other therapies didn't
17:35 How her brain turned a positive Lyme test negative
25:27 The pause technique for breaking negative thought loops
34:01 Where to find the re-origin community
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Dr. Scott McMahon | Chronic Lyme, mold illness and the CIRS connection doctors miss
Episode 252
Monday, July 27, 2026 • Duration 42:39
What if the reason your Lyme treatment isn't working has nothing to do with the infection itself?
In this episode of Integrative Lyme Solutions, Dr. K talks with pediatrician Dr. Scott McMahon, Medical Director at Moldco, about the immune system reaction that keeps so many chronic Lyme patients sick long after the bacteria are gone. Dr. McMahon explains how dead pathogen fragments can keep triggering the innate immune system, why standard labs like CBC and CRP almost always miss it, and which specific markers (TGF-beta 1, MMP9, C4a) tell the real story. He also walks through his treatment approach with binders, a low-amylose diet, and VIP peptide therapy, and shares data from his work on children with recurrent headaches, stomach issues, and PANS/PANDAS whose symptoms resolved once the underlying inflammatory response was addressed.
This conversation covers what chronic inflammatory response syndrome (CIRS) is, why it so often overlaps with Lyme and mold illness, and how the hypothalamus, blood-brain barrier, and autonomic nervous system get pulled into the mix. If you've been treating the infection but still aren't getting better, this episode explains the piece that's likely missing.
Key Takeaways:
0:00 Introduction
0:53 Immune response drives chronic Lyme symptoms
2:53 Key labs standard testing misses
6:30 Dead pathogen fragments trigger the immune system
9:33 Binders, diet and VIP reset the response
16:57 Kids' unexplained symptoms trace back to CIRS
30:00 CIRS disrupts the blood-brain barrier and hormones
35:26 Low-cost telehealth model closes the access gap
Dr. Jonathan Streit | Why Killing Lyme Isn't the Answer: Terrain Theory, Microglial Activation & the BioRestorative Method
Episode 2
Monday, July 13, 2026 • Duration 35:11
What happens when every antibiotic, every protocol, every specialist leaves your loved one worse, not better? For Dr. Jonathan Streit, that wasn't a hypothetical. It was his wife, wasting away, while he carried her to the bathroom and raised a toddler. That breaking point became the foundation of everything he now does for Lyme patients.
In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Jonathan Streit to unpack why killing the infection is only part of the picture, and often the wrong place to start. They dig into his BioRestorative Method, which targets six interconnected systems including the autonomic nervous system, gut microbiome, and neuroplastic retraining. Dr. Streit also introduces a concept most Lyme-literate practitioners aren't talking about: microglial activation, the brain's immune response that can keep you sick long after the infection is gone. If you've done everything right and still don't feel well, this episode may finally explain why.
Key Takeaways:
0:00 Introduction
1:36 How Dr. Streit's wife's battle with Lyme changed his entire career path
8:07 Why eight rounds of antibiotics made her worse and the moment he said "we're done"
10:49 The BioRestorative Method's six-system approach to healing Lyme
14:31 Why Dr. Streit doesn't believe in the Herxheimer reaction
17:03 Tailored protocols over stock supplements and why cookie-cutter Lyme treatment fails
25:00 Silent Spark: how microglial activation keeps you sick after the infection clears
29:27 Why limbic retraining programs have limited results without addressing microglial activation
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Donna Gates | Lyme Disease, Gut Ecology and Why Fermented Foods Beat Probiotics for Chronic Infections
Episode 1
Monday, June 29, 2026 • Duration 42:30
What if the fatigue, brain fog, and infections you've been fighting for years all trace back to the same root - a gut that never had a chance to recover?
In this episode of Integrative Lyme Solutions, Dr. K sits down with Donna Gates, author of The Body Ecology Diet and founder of Body Ecology, to cover a lot of ground: long COVID, Lyme disease, candida, biofilms, autism, and why fermented foods do something no probiotic capsule can replicate. Donna shares her own decades-long journey through antibiotic-induced illness, yeast overgrowth, and a recent long-haul COVID experience that sent her back to the drawing board - and ultimately led to her new book, Taming the Dragon. The conversation gets into why Lyme and candida are so resistant to treatment, how biofilms protect pathogens from the immune system, the surprising role of fermented vegetables in nasal health, and what the diversity inside a single head of cabbage has to do with your brain function. If you or someone you love is dealing with a chronic infection and not getting answers, this episode is worth your full attention.
Key Takeaways:
0:00 Introduction 1:51 How the Body Ecology Diet started with a yeast infection and a chance meeting 6:09 Why the inner ecosystem concept predated the term gut microbiome by 12 years 15:00 Long COVID as a chronic viral flare and how the antiviral diet works 18:00 Taming the dragon: keeping viruses dormant through an alkaline mineral-rich body 22:00 Fermented vegetables and the histamine myth most people get wrong 29:23 Lyme and candida both hide behind biofilms and why antibiotics alone fail 36:05 Fermented vegetable juice in your nose to break up nasal biofilm
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Resources:
Body Ecology -
Isabel Rose | Congenital Lyme Disease, Motherhood & Finding Hope When the System Fails You
Episode 251
Monday, June 15, 2026 • Duration 45:18
What if you passed a disease to your children before they were even born, and didn't find out until decades later?
In this episode of Integrative Lyme Solutions, Dr. K sits down with Isabel Rose, chair of Mothers Against Lyme and board member of Project Lyme, to talk about congenital Lyme disease, what it is, why most OBs are unprepared for it, and what testing and treatment during pregnancy actually looks like. Isabel was bitten at eight, undiagnosed until 48, and carried two children to term while unknowingly infected. She's not speaking from research. She's speaking from her own life. This conversation covers the downstream effects on children, from developmental delays and autism spectrum disorders to PANS/PANDAS, and why early intervention and community support can change everything. If you're navigating Lyme and motherhood, this is the episode you've been looking for.
Key Takeaways:
0:00 Introduction
1:15 Mothers Against Lyme and Project Lyme
2:25 Lyme disease and pregnancy
5:07 What congenital Lyme disease is
6:32 Maternal Lyme infection and autism spectrum disorders
11:29 Testing and treating before and during pregnancy
19:19 Isabel's story, two children two outcomes
23:29 NuCalm and nervous system regulation
30:03 Other Lyme transmission routes
31:40 The guilt mothers carry
33:21 Undiagnosed for 40 years
37:00 How to join the support group
42:10 Why community matters in Lyme disease
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Elena Herning │ Undiagnosed for 25 Years: How TruDOSE™ IV PRP Reversed Chronic Lyme & Mold Illness
Episode 250
Monday, June 1, 2026 • Duration 48:13
Twenty-five years of being dismissed, misdiagnosed, and told it was all in her head. By the time Elena Herning finally got answers, she had lost her home, her belongings, her ability to drive, and very nearly her life.
In this episode of Integrative Cancer Solutions, Dr. K sits down with Elena Herning, patient advocate and TruDOSE™ ambassador, to trace her harrowing journey through undiagnosed Lyme disease, co-infections, toxic mold exposure, mast cell activation syndrome, POTS, MOG antibody disease, and COVID - and the single therapy that finally turned it all around. Elena breaks down what dose-specific IV platelet-rich plasma (TruDOSE™) actually does inside the body, why it crosses the blood-brain barrier, how it unwinds inflammatory loops that conventional medicine never addresses, and what it felt like to go from writing goodbye letters to her children to logging mile six on a treadmill. If you or someone you love is caught in the chronic illness spiral with no answers and no end in sight, this episode is for you.
Key Takeaways:
0:00 Introduction
1:52 Undiagnosed for 25 years and what that looked like day to day
3:29 How a hysterectomy became the breaking point that revealed Lyme
9:04 Why Lyme is rarely the only problem
27:00 After energy healers, ozone, and a near liver transplant
29:38 What TruDOSE™ IV PRP is and how it differs from standard PRP
32:11 First treatment results and how fast things shifted
37:17 How dose-specific platelets cross the blood-brain barrier
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.
____________________________________
WORK WITH DR. KARLFELDT:
The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies available. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor, contact us at:
📞 208-338-8902
📧 info@TheKarlfeldtCenter.com
🌐 TheKarlfeldtCenter.com
____________________________________
📖 FREE EBOOK: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery
Get your copy at: store.thekarlfeldtcenter.com/products/breaking-free-from-lyme
Use code LYMEPODCAST for 100% off
____________________________________
CONNECT WITH DR. KARLFELDT:
Instagram: instagram.com/thekarlfeldtcenter
Facebook: facebook.com/thekarlfeldtcenter
____________________________________
MORE PODCASTS FROM DR. KARLFELDT:
🎙 The Dr. K Show — Integrative medicine, functional medicine, biohacking, and longevity for optimizing health and performance.
🎙 Integrative Cancer Solutions — Evidence-based integrative therapies and real patient stories for those navigating a cancer diagnosis.
The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies available. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor, contact us at:
📞 208-338-8902
📧 info@TheKarlfeldtCenter.com
🌐 TheKarlfeldtCenter.com
____________________________________
📖 FREE EBOOK: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery
Get your copy at: store.thekarlfeldtcenter.com/products/breaking-free-from-lyme
Use code LYMEPODCAST for 100% off
____________________________________
CONNECT WITH DR. KARLFELDT:
Instagram: instagram.com/thekarlfeldtcenter
Facebook: facebook.com/thekarlfeldtcenter
____________________________________
MORE PODCASTS FROM DR. KARLFELDT:
🎙 The Dr. K Show — Integrative medicine, functional medicine, biohacking, and longevity for optimizing health and performance.
🎙 Integrative Cancer Solutions — Evidence-based integrative therapies and real patient stories for those navigating a cancer diagnosis.
Discover shows related to Integrative Lyme Solutions with Dr. Karlfeldt, based on actual content similarities. Explore podcasts with similar topics, themes, and formats, backed by real data.
