Health Longevity Secrets – Details, episodes & analysis

Can rapamycin be the key to unlocking a longer, healthier life? Join us as Krister Kauppi, a dedicated health and longevity enthusiast, shares his captivating journey from a personal health scare to discovering the potential of rapamycin as an alternative to intermittent fasting. We delve into the science behind this intriguing compound, focusing on how it inhibits mTOR and activates catabolic processes, potentially slowing down aging and reducing the incidence of age-related diseases. Together, we explore the delicate balance between anabolic and catabolic processes and the significant roles that insulin, insulin-like growth factor, and testosterone play in these pathways.

Krister also opens up about his personal experiences with rapamycin, highlighting the crucial importance of personalized dosages and the remarkable benefits he observed, such as improved dental health and reduced inflammation. We discuss the exciting concept of longevity cocktails—combinations of fasting, rapamycin, and other interventions aimed at extending lifespan. Learn about the innovative work being done at the Rapamycin Longevity Lab and their mission to create advanced longevity solutions, leveraging cutting-edge technology like Ora Biomedical's WormBot. This episode is a compelling invitation to join us on a groundbreaking journey towards enhancing human longevity.

https://masteronething.com/
https://www.linkedin.com/in/krister-kauppi/recent-activity/all/

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This week we explore the secrets of our DNA and take control of our health destiny as we join Dahlia Attia-King, the innovative CEO of Panacea, as we examine the transformative potential of clinical-grade gene sequencing. We delve into how this technology eclipses the consumer-grade genotyping you might know from popular companies like 23andMe, offering a more comprehensive analysis with the power to revolutionize disease prevention and personalized health strategies. Dahlia's insights into the cutting-edge advances in whole exome and genome sequencing will leave you awestruck at the possibilities that lie within our very own genetic code.

When it comes to the intimate details of our genetic blueprint, protecting privacy is paramount. Panacea's trailblazing use of blockchain technology ensures that the power over your personal genetic information remains firmly in your hands. Dahlia and I discuss the ethical landscape of genetic testing companies, the vital importance of consent, and the profound consequences that informed access to one's genetic information has on individual health choices. Listen to heartfelt stories that underscore the dramatic impact of understanding and acting upon genetic risks, which, contrary to popular belief, can often be mitigated with the right lifestyle adjustments and medical interventions.

https://seekpanacea.com/

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Can fasting be the key to unlocking a healthier and longer life? Join Josh Duhamel and I as we explore this compelling question and delve into the transformative benefits of a 72-hour fast. 

Josh is an actor known for his performances in films such as ‘Shotgun Wedding’ and the ‘Buddy Games’ franchise. But what you may not know is that he is also a longtime health and longevity enthusiast and is very knowledgeable about the latest developments in this important space.

In this episode, we catch Josh in the middle of his first 72 hour fast and share his personal experiences with extended fasting, discussing the profound impacts of ketosis and autophagy on our bodies. We also highlight the importance of community and peer support in overcoming moments of temptation, ensuring we stay motivated throughout the fasting journey. 

We don't stop at just the physical benefits; we dive into the psychological and social aspects as well. From the clarity and energy boosts during the fast to the anticipation of that first meal post-fast, you'll gain a comprehensive understanding of what to expect. We also address common concerns about muscle loss and the potential for healthier eating habits post-fast. 

To top it all off, we discuss our plans for a co-hosting a fasting event in the fall where we can all share in the experience of fasting together.  It will be aimed at raising awareness about fasting's health benefits and emphasizing the power of community in making positive lifestyle changes. Stay tuned for later updates about that as well as a new health longevity company that Josh and I will be announcing soon. 

Tune in, and you might just find yourself inspired to join us on this transformative health journey!

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It's one thing to hear the physicians talking about rapamycin for longevity. But today we get to hear for from one of the citizen scientists who is taking it himself. Our guest today is Gregg Davison, a student of longevity science.

It began for him over six years ago when a news article making intriguing claims came to his attention. The series of scientific studies radically extended mouse lives up to 25% longer, all due to a drug, a drug that Gregg subsequently takes. Gregg studies have grown and today he speaks regularly about why and how we age and how a drug may be able to do for humans what it does for other species that has been administered to Gregg has a Bachelor of Science in Biology from the University of Utah. He has worked in the gurney cellular lab on the Human Genome Project, and also as a paramedic in the greater Salt Lake area for over 10 years. Before we start the episode, if you liked what you hear, please consider supporting the work we do as well as joining us on your personal health longevity journey. You can do both by becoming a member of our community. The benefits include a private messaging area, live QA sessions, weekly premier videos, product discounts, free giveaways, and much more. You can join for as little as $1 per month, and the first month is free. See the link in the show notes for more information.

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Timestamps:

• 00:15 – Introduction to Gregg Davison
• 01:55 – Rapamycin
• 04:09 – Damage to DNA
• 05:06 – Reactive Oxidative Species
• 05:29 – Piper Functionality
• 07:50 – Energy Sensing Pathway
• 10:14 – Synaptic Cells
• 12:40 – Senescence
• 14:55 – Biological Clocks
• 18:54 – Master Nutrient Sensing Pathway
• 22:40 – mTor
• 33:21 – Lipids
• 39:27 – Phenotypes of Aging
• 44:07 – Lithium

#rapamycin #cell #longevity #senescence #aging #drug #negligiblesenescence #lithium #immune system #metformin
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The idea that Alzheimer's disease can be prevented, and even reversed is transforming the medical world. Today we get to speak with one of the key people responsible for this revolution. An internationally recognized expert in the mechanisms of neurodegenerative diseases. Dr. Dale Bredesen's research explores previously uncharted territory in explaining the physical mechanism behind the erosion of memory seen in Alzheimer's disease, and has opened the door to new approaches to treatment. This work has led to the identification of several new therapeutic processes that are showing remarkable early results.

Dr. Bredesen is a prodigious innovator in medicine, with over 30 patents to his name. Notably, he put most much of his findings and research into the 2017 New York Times bestseller book, The End of Alzheimer's. His most recent book, the first survivors of Alzheimer's also prevents presents the stories of seven individuals who reverse their cognitive decline using his recode protocol. Dr. Bredesen graduated from Cal Tech and earned his MD from Duke University and served as chief resident neurology at the University of California San Francisco before joining joining Nobel laureate Stanley prisoners laboratory at UCSF as an NIH postdoctoral fellow. He has held faculty positions at UCSF, UCLA and the University of California, San Diego. Dr. Bredesen also directed the program on Aging at the Burnham Institute before joining the Parker Institute in 1998, as founding president and CEO.

LINKS:

• The End of Alzheimer's Book - LINK
• The First Survivors of Alzheimer's - LINK
• Apollo Health - LINK

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#alzheimer #cognitivedecline #braindisease #aging #cognition #recode #prevention #oxygenation #amyloid #inflammation #toxicity
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Today we get to hear from six world authorities on longevity, who will be speaking at the upcoming  RAADfest festival in October 2022. They're going to preview their presentations with a five or 10 minute discussion about the topics that they will be talking about at the upcoming festival.

We'll be hearing from Liz Parrish, who is the CEO of BioViva Corporation using gene therapy for longevity. Dr. Dobri Kiprov, who will be discussing plasmapheresis and his recent article in geroscience on how that affects human longevity, Bill Faloon and Bill Andrews will also be speaking from the Life Extension Foundation and Sierra Sciences. And finally, Dr. Sandra Kaufmann will be discussing her new book on the Kaufmann protocol. And also yours truly, we'll be discussing rapamycin briefly as well. And now, please enjoy this sneak preview of RAD fest 2022.

LINKS:

RAADfest: https://raadfest.com/
People Unlimited Inc.: https://peopleunlimitedinc.co
BioViVa: https://bioviva-science.com/
LifeExtension®: https://www.lifeextension.com/
Sierra Sciences: https://sierrasci.com/

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Timestamps:

• 00:19 – Introduction to Speakers
• 02:58 – Longevity
• 05:07 – RAAD Fest
• 10:42 – Therapeutic Plasma Exchange
• 12:38 – Alzheimer’s Disease
• 13:20 – Plasmapheresis
• 15:10 – Rapamycin | mTor
• 17:46 – Cardiovascular Disease
• 21:04 – Healthspan & Lifespan
• 28:34 – Mitochondrial Transition Pore
• 31:40 – Gene Therapy
• 51:55 – Best Choice Medicine
• 59:06 – BioViva
• 1:03:21 – Psychological Stress

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#RAADfest #longevity #genetherapy #lifespan #aging  #treatments #rapamycin #plasmapheresis #kaufmannprotocol
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Stem Cells and Regenerative Medicine continue to dominate medical news. Let's take a look at how they work and how they can specifically affect things like inflammation, apoptosis, epigenetics and mitochondrial health.

From an expert in the field, Joy Kong MD, is the founder and medical director of Thea Center for Regenerative Medicine. She is also the founder of Chara Biologics, a company that provides regenerative medicine products to physicians across the United States. Dr. Kong graduated from UCLA School of Medicine and completed a residency in psychiatry. She is a member of the American Academy of anti aging medicine. She is certified in advanced cellular therapeutic protocols. She's board certified by the American Board of Psychiatry and Neurology and the American Board of Addiction Medicine. She is also the president of the American Academy of integrative cell therapy, and is an avid educator helping physicians to become fully trained in the science and practice of regenerative medicine.

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LINKS:

(Thea Center for Regenerative Medicine has been renamed UPLYFT Longevity Center)
https://www.uplyftcenter.com/

Chara Biologics
https://charabiologics.com/
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Timestamps:

• 00:00     – Introduction to Jong Kong MD
• 02:05     – Tiger of Beijing book
• 03:04     – Background and Stem Cells
• 20: 25    – Stem Cell Therapy
• 23:00     – Tumor Growth
• 34:00     – DNA, RNA
• 38:45     – Mesenchymal Stem Cells
• 44:33     – Lyme Disease
• 45:15     – Inflammation, Fibrosis
• 52:20     – Ballpark Figures
• 58:13     – Great Practices

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Our guest today has setout to do accomplish something that decades of research and billions of dollars from the top pharmaceutical companies in the world have failed to do- that is to demonstrably reverse alzheimers disease. And he proposes to validate it  with what is the gold standard of evidence based medicine- the randomized controlled clinical trial. 

 Matthew Phillips MD is a full-time clinical and research neurologist at Waikato Hospital, Hamilton, New Zealand. His foremost passion is to explore the potential feasibility, safety, and efficacy of metabolic therapies, particularly fasting and ketogenic diets, in creating alternate metabolic states that may improve not only the symptoms, but also function and quality of life, for people with a variety of difficult disorders.

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It’s not enough for medical researchers to understand the methods of Alzheimer’s prevention using lifestyle and other tools. This message must be delivered to frontline healthcare workers and the public at large.

Peggy Sarlin loves to bring the power of great storytelling to broadcast, advertising, museums, books, and songs. She hosted two acclaimed online series on brain health, garnering more than 4 million views, and wrote the accompanying books. Peggy is also a singer-songwriter/performer who just released her second album. www.peggysarlin.com

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What are the possibilities for gene therapy for the treatment of dementia or even to slow or reverse aging? Let’s find out as we review the field and take a look at a new publication from one of the experts in the area. 

Patrick Sewell MD currently has an international medical practice specializing in regenerative medicine, gene therapy, stem cell therapy,  and innovative cancer therapies. His background includes over 20 years of cancer research, including development of minimally invasive treatment and stem cell procedures. Dr Sewell’s training includes internal medicine, Diagnostic Radiology, and Interventional Radiology.  He received his MD and residency  from Louisiana State University School of Medicine. He completed fellowships at University of Mississippi Medical Center where he later joined the faculty. 

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