In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with special guests, Angela Wilson McDonald, Global VP, Education and Customer Success, and Brian Jones, Ph.D., Global VP, R&D Pharma and Biomedical Innovation, about what the scientific literature says about microneedling, acne and granulomas. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

0:00 Introduction and disclaimers
1:04 Special guest, Dr. Brian Jones 
3:13 Define episode topic: the science behind microneedling and acne
6:00 Social media video detailing a skin reaction months after a microneedling treatment 
9:12 What is acne-prone skin? 
13:11 Can acne be spread?
14:49 Clip from S1 Ep2 "Acne" with Dr. James Leydon
17:27 What causes acne?
21:20 Inflammation and acne
23:44 Microneedling studies in individuals with acne-prone skin
28:16 Lack of scientific evidence that microneedling worsens acne 
35:15 Granulomas and risks of microneedling topicals into skin
40:33 Allergic reactions to metals 
43:48 Acne is a multifactorial condition 
45:09 Return to discussion about social media video 
49:00 Microneedling practices associated with granulomas
51:20 Closing remarks

REFERENCES

24:00 Mehran, G., Sepasgozar, S., Rohaninasab, M., Goodarzi, A., Ghassemi, M., Fotooei, M., & Behrangi, E. (2019). Comparison between the therapeutic effect of microneedling versus tretinoin in patients with comedonal acne: a randomized clinical trial. Iran J Dermatol, 22, 87–91. https://www.iranjd.ir/article_100199_17b3901512f6a7d987df9c24299a856d.pdf

25:49 Alqam, M. L., Jones, B. C., & Hitchcock, T. M. (2023). Topical application of skin biome care regimen containing live cultures and ferments of Cutibacterium acnes defendens strain XYCM42 and the impact on clinical outcomes following microneedle-induced skin remodeling. The Journal of Clinical and Aesthetic Dermatology, 16(12), 18–30. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729805/pdf/jcad_16_12_18.pdf

31:24 Alqam, M. L., Jones, B. C., & Hitchcock, T. M. (2023). Study to determine the safety and efficacy of microneedling as an effective treatment for acne vulgaris. Skin Health and Disease, 3(5), e264. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549865/pdf/SKI2-3-e264.pdf

35:21 Heck, E., & Traboulsi, D. (2022). A case of a delayed granulomatous reaction on the face following microneedling: A case report. SAGE Open Medical Case Reports, 10, 2050313X221102489. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178993/pdf/10.1177_2050313X221102489.pdf

35:47 Yadav, S., & Dogra, S. (2016). A cutaneous reaction to microneedling for postacne scarring caused by nickel hypersensitivity. Aesthetic Surgery Journal, 36(4), NP168–NP170. https://doi.org/10.1093/asj/sjv229

38:40 Handal, M., Kyriakides, K., Cohen, J., & Hoffman, C. (2023). Sarcoidal granulomatous reaction

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with Jigna Patel, MD, of Vedaskin, and Angela Wilson McDonald, Global VP, Education and Customer Success, about retinoids and their impact on the skin's microbiota. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.


0:00 Intro
1:06 Special guest, Dr. Jigna Patel
4:57 Holistic approaches
6:10 Retinoids & patient considerations
10:12 Safety concerns
13:40 What do retinoids do?
18:29 Changing approaches to skincare
21:06 Do modern societal norms accelerate aging?
25:25 Accepting progression in skincare
31:55 Intermission for puzzle of the day
35:28 How Xycrobe technology came to be
43:50 Using commensal microbes for better skin health
48:20 Translating science into patient care
53:59 C. acnes and retinoid receptors
56:50 Closing remarks

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options.  In this episode, the team discusses hyperhidrosis and an FDA-cleared treatment device with Dan Moyer, VP of Marketing and Sales at RA Fischer Co. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options.  In this episode, the team discusses exosomes.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options.  In this episode, we discuss hair loss with Kyle Gillett, MD, Board Certified Family Medicine, Board Certified Obesity Medicine.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options.  In this episode, we discuss melasma with Amelia Hausauer, MD, a board-certified dermatologist.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options.  In this episode, we discuss the skin barrier with Jennifer Holman, MD, FAAD, a board-certified dermatologist, board-certified micrographic dermatologic surgeon, and a fellow of the American Academy of Dermatology.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options.  In this episode, we discuss skin cancer with Jennifer Holman, MD, FAAD, a board-certified dermatologist, board-certified micrographic dermatologic surgeon, and a fellow of the American Academy of Dermatology.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a bi-monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. In this episode, Dr. Hitchcock and Angela Wilson McDonald discuss biomecare and why Xycrobe, the novel technology found in BIOJUVE, is "holistic" biomecare.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a bi-monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. In this episode, Dr. Hitchcock and Angela Wilson McDonald discuss the Xycrobe journey, a novel technology found in BIOJUVE, a topical probiotic for the skin biome and Crown's newest innovation. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatment options.  In this episode, featuring special guest, Dr. Elizabeth Houshmand, Dr. Hitchcock and his team explore various factors of the skin biome and why caring for it shouldn't be one size fits all.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a bi-monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. In this episode, Dr. Hitchcock, Angela Wilson McDonald, Dr. Jose Maldonado, and special guest, Dr. Doris Day, discuss the association of yeast with acne. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with Angela Wilson McDonald, Global VP, Education and Customer Success, and Brian Jones, Ph.D., VP, R&D and Biomedical Innovation, about biome boosted microneedling and the clinical study to support it. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.


0:00 Introduction
2:50 Before/after photo from Crown "Biome-boosted microneedling" clinical study 
6:34 Story behind the SkinPen + BIOJUVE biome-boosted microneedling study 
9:50 Treatment of acne scars
13:08 Optimal environment for skin remodeling 
16:40 Philosophy of the BIOJUVE regimen
19:00 How topicals influence skin physiology 
23:03 Study design and rationale
28:20 Results 
30:30 Before/after photos 
33:20 Opportunity to enhance microneedling results 
38:25 Improvement beyond acne scarring
40:20 Remodeling process
43:50 Closing remarks


Alqam, M. L., Jones, B. C., & Hitchcock, T. M. (2023). Topical application of skin biome care regimen containing live cultures and ferments of Cutibacterium acnes defendens strain XYCM42 and the impact on clinical outcomes following microneedle-induced skin remodeling. Journal of Clinical and Aesthetic Dermatology, 16(12), 18–30. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729805/pdf/jcad_16_12_18.pdf

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a bi-monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. In this episode, Dr. Hitchcock, Angela Wilson McDonald, Dr. Jose Maldonado, and special guest, Dr. Doris Day, discuss the role fungal microorganisms play in acne development. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. In this episode, Dr. Hitchcock, Angela Wilson McDonald, Ndashe Kamungu, BS, and special guest, Dr. Doris Day, continue their discussion of the effects of skin disease, specifically Atopic Dermatitis, on certain populations and how geography may have an influence. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. In this episode, Dr. Hitchcock, Angela Wilson McDonald, Ndashe Kamungu, BS, and special guest, Dr. Doris Day, discuss the effects of skin disease on certain populations and how geography may play a role. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. In this episode, Dr. Hitchcock, Dr. Brian Jones, and Dr. Jose Maldonado address a mail bag of dermatology questions posed to our skin scientists by every day people. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.
 
#sciencefacts #science #skinscience #healthyskin #skincare #skincareproducts #microbiome #skincmicrobiome #skincareroutine

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatment options.  In this episode, Dr. Hitchcock, Dr. Brian Jones and Jeff Bedard continue their discussion of what it takes to bring topical products to market, specifically as it relates to R&D.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatment options.  In this episode, Dr. Hitchcock, Dr. Brian Jones and Jeff Bedard discuss what it takes to bring topical products to market.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatment options.  Our ninth episode discusses trends in the marketplace and whether they are legitimate, a gimmick, or somewhere in between. Is there science? Topicals or devices, is there any truth to these products? 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Collagen - what do you think of when you hear this word? "Collagen" is often used in marketing but what is it really? How does it work and how does it impact our skin and its appearance? In this episode we break down the science behind this protein and the role it plays in the skin's aging process.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. Our seventh episode features Gregory Laurence, MD, a cosmetic surgery specialist, and today our discussion is biomecare, part 2.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Chapters:
0:00 Intro
0:30 Episode Introduction
1:55 Q&A with a product consumer
4:30 Probiotic and biomecare skincare
11:05 Testing for different bacterial strains
17:00 Different levels of bacterium diversity can affect skin health
28:05 The role of senescent cells in ageing
32:00 The life cycle of non-reproducing bacteria
33:40 Formulating skincare products with life microbes
40:25 Justice for C. acnes!
41:11: Wolves, beagles, and bacteria
50:30 Not bacteria species specific it's bacteria strain specific
55:20 C. acnes strains can be in symbiosis with the skin
58:03 Caring for the skin biomecare
59:15 Closing thoughts from Dr. Hitchcock and Dr. Laurence

#Biomecare #skincare #microbiome #science #sciencefacts #health #healthyskin

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. Our sixth episode features Gregory Laurence, MD, a cosmetic surgery specialist, and today our discussion is about biomecare. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options. In this episode, Dr. Hitchcock, Angela Wilson McDonald, and special guest, Dr. Doris Day, discuss Rosacea. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

0:00 Introduction
0:45 Dr. Doris Day
2:20 What is rosacea?
5:10 Demodex theory of rosacea
8:55 Bacteria associated with rosacea
12:35 Inflammatory triggers
13:41 Systemic biologics 
15:45 Impacts of different topicals
20:25 Role of stress in rosacea
26:34 Closing statements

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatment options. In this episode, featuring Dr. Brian Jones and Chad Sulak, ProGen PRP Brand Manager, we discuss SPF. 
 
 The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

 

References:

1) https://www.fda.gov/about-fda/center-drug-evaluation-and-research-cder/sun-protection-factor-spf

2) Conway et al, Acute toxicity of the uv filter oxybenzone to the coral galaxea fascicularis. Science of the total Environment 796 (2021) HTTPS://doi.org/10.1016/j.scitotenv.2021.14866

3) de Barros Marangoni et al., Unraveling the different causes of nitrate and ammonium effects on coral bleaching. Nature/Scientific Reports 2020 HTTPS://doi.org/10.1038/s41598-020-68916-0

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatments options.  In this episode, featuring Dr. Doris Day, MD, FAAD, MA, a world renowned cosmetic dermatologist, educator and pioneer in aesthetics, we discuss skin aging and longevity.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatments options.  Our third episode discusses skin remodeling.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatments options.  Our second episode focuses on acne and features Dr. James Leyden, a pioneer in the field of acne, rosacea, retinoids and photoaging, and Dr. Doris Day, MD, FAAD, MA, a world renowned cosmetic dermatologist, educator and pioneer in aesthetics.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer, and co-hosted by Angela McDonald, Senior Director of Education with Crown Aesthetics, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series will dig into hot topics within dermatology and aesthetics and will challenge the audience to think a bit differently about current skin treatments options.  Our inaugural episode features Dr. Doris Day, FAAD, MA, a world renowned cosmetic dermatologist, educator and pioneer in aesthetics and kicks off the two way discussion about the skin microbiome.

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with David Weir, MSN, APRN, NP-C, about exosomes and the challenge of limited substantiated science.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.


0:00 Introduction
0:55 Guest, David Weir
3:00 Exosomes in the aesthetic industry 
7:12 Studies with exosomes
10:40 Questions of safety and dosage 
12:50 Exosome sources 
18:10 How genetics play into exosome contents 
24:40 Responsibilities of consumers, providers, and companies 
28:40 What questions patients should ask about exosome products
33:40 Concluding statements

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with Angela Wilson McDonald, Global VP, Education and Customer Success, and Dr. Jigna Patel of Vedaskin, about how mind, skin, and gut are all connected.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc. or its affiliates, and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.


0:00 Intro
1:07 Dr. Jigna Patel
4:40 Gut, brain, skin connection
8:10 Derm layers 
12:38 Microbiome similarities across individuals
16:28 Hair follicles
20:37 Nervous system regulation
25:00 Microflora balance 
29:25 Immune reactions 
30:54 Microbe secretions
33:00 Clinical evaluation for patients
37:36 Medication influence 
39:18 Food and sleep
44:20 Reevaluating care
49:40 Closing

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with Angela Wilson McDonald, Global VP, Education and Customer Success, and Dr. Jinga Patel of Vedaskin, about the habits and knowledge we have learned over time and now need to unlearn, and why.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc. or its affiliates, and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options.  In this episode, Dr. Hitchcock speaks with David Weir, NP, about microneedling with and without RF technology.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

Hosted by Thomas Hitchcock, Ph.D., Chief Science Officer at Crown Laboratories, The Skin Science Podcast is a monthly podcast that covers topics relating to skin health. The series digs into hot topics within dermatology and aesthetics and challenges the audience to think a bit differently about current skin treatment options.   

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent. 

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with Ted Lain, MD, MBA, Chief Medical Officer at Sanova Dermatology and Co-Founder and Co-Director of the Science of Skincare Summit, about the skin biome and implications of topicals.

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with special guest, Jigna Patel, MD, of Vedaskin, and Angela Wilson McDonald, Global VP, Education and Customer Success, about whether skin aging is correlated to the skin's microbiome. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

0:00 Intro
1:24 Special Guest, Jigna Patel MD
5:21 Introduce topic, aging & the skin microbiome 
11:10 Aging as a disease state
15:15 Band-aid treatments vs reversing aging
19:50 Relationship between skin microbiome and age 
24:40 Commensal vs pathogenic in whole ecosystems
28:20 Nurturing the skin's natural properties
32:45 Microbe diversity and age
37:18 Gut vs skin microbiomes in age
42:27 Closing remarks

Reference at 37:50: Woo YR, Kim HS. Interaction between the microbiota and the skin barrier in aging skin: a comprehensive review. Front Physiol. 2024;15:1322205. doi:10.3389/fphys.2024.1322205

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with special guests, Jigna Patel, MD, of Vedaskin, and Ansar Mahmood, MD, Consultant Trauma & Orthopedic Surgeon, about regenerative medicine and how it pertains to skin science. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.

In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with Angela Wilson McDonald, Global VP, Education and Customer Success, about why BIOJUVE is not skincare. 

The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.