The Obesity Guide with Matthea Rentea MD – Details, episodes & analysis
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The Obesity Guide with Matthea Rentea MD
Matthea Rentea MD
Frequency: 1 episode/5d. Total Eps: 223

Matthea Rentea MD leads discussions on obesity and chronic weight management. Her guests range from experts in the fields that intersect with obesity and wellness, to individuals successful in their weight journey. She is a Board certified Internal Medicine and Diplomate of the American Board of Obesity Medicine and founder of the Rentea Metabolic Clinic, a Telehealth clinic for residents of the state of Indiana and Illinois that helps comprehensively with weight management. This podcast is for information and education purposes only. No medical advice is being given. Please talk to your physician for what is right for you.
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Your Friday Five: The Power of the Pivot — Finding Peace When Life Changes Your Plans
vendredi 7 novembre 2025 • Duration 07:54
In this quick and heartfelt episode of Your Friday Five, Dr. Matthea shares a personal story about losing access to her favorite walking track — and the unexpected lessons it revealed about change, flexibility, and gratitude.
She explores:
- How to pivot when life throws you a curveball
- The importance of solving for what actually matters
- Why resistance makes change harder
- How gratitude can transform frustration into peace
- A reminder that sometimes losing one routine opens the door for something even better
Dr. Matthea also gives a sneak peek into upcoming podcast interviews and reflects on the grounding power of community during busy seasons.
Mentioned in this episode:
- Monday’s inspiring interview with Jamie S. Sellner on creating life rules that transform everything
- The 30/30 group’s continued momentum leading up to the December Health & Momentum Challenge
Takeaway:
When change shows up uninvited, ask yourself — “What really matters here?” Then pivot quickly toward that.
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
340 Pounds Down: Jamie Selzler's Four Rules for Lasting Change
Season 1 · Episode 145
lundi 3 novembre 2025 • Duration 50:52
There are moments in our work that stay with you long after the conversation ends. My interview with Jamie Selzler was one of those moments.
At 652 pounds, Jamie's world had become frighteningly small. Short walks left him breathless, and the haunting reality that people his size rarely lived past 50 forced him to face where his life was heading.
What followed wasn't a quick fix or dramatic intervention. It was a complete transformation built on small promises, deep self-compassion, and the support of GLP-1 medication. Over three years, Jamie lost more than 340 pounds. But what moved me most wasn't the number on the scale, it was how he rebuilt his relationship with himself.
In this powerful conversation, Jamie shares his four rules for lasting change, why he keeps a notebook with hundreds of handwritten wins, and why he refuses to set a goal weight. We talk about forgiving yourself, keeping promises to yourself, and why the happier life isn't waiting at some distant finish line—it's happening right now, in every small choice you make.
References
You can follow Jamie's journey on TikTok: @JamSelz or Instagram: @jselzler.
Season 2 of Behind the Curtain is now LIVE! The 21-Day Momentum & Health Challenge gives you the mindset and tools to build lasting change in just a few minutes a day. Learn more here.
Audio Stamps
01:13 - Jamie Selzler shares his story of losing over 300 pounds and how GLP-1 medications transformed his health and mindset.
03:39 - Reflecting on decades spent over 500 pounds and the repeated cycle of weight loss and regain.
07:05 - The wake-up moments that changed everything, from falling on the beach to realizing his life was at risk.
13:14 - Why bariatric surgery was never offered and how he might have considered it if it had been.
19:11 - Learning to forgive himself, release shame, and show compassion for his past choices.
22:00 - Starting GLP-1s, losing food noise, and the small mindset shifts that built lasting change.
23:30 - Keeping promises to himself and focusing on consistency over motivation.
34:32 - Letting go of the scale and shifting from output goals to input goals.
37:28 - The power of celebrating every small win and how tracking progress rewired his mindset.
45:10 - Jamie’s three pieces of advice: stop comparing, build your team, and find happiness in the process, not just the result.
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
After the Honeymoon Phase: 3 Strategies for Long-Term GLP-1 Success
Season 1 · Episode 141
lundi 6 octobre 2025 • Duration 15:54
The excitement of those first 6–12 months has faded. The scale isn't moving like before, your body feels different, and suddenly year two of GLP-1 treatment doesn't feel straightforward anymore.
This is where many people hit a wall. Progress slows, plateaus arrive, and it's easy to worry you're failing. After months of rapid changes, the slower pace feels frustrating… even defeating. Add in metabolic adaptations and the pressure of maintaining new habits, and year two can feel like uncharted territory.
But this isn't the end of your progress. In fact, it's where sustainable success begins. In this episode, we'll explore what to expect in year two and beyond, including:
- Three key mindset shifts to help you thrive past year one
- Why plateaus don't mean your medication stopped working (and what to do instead)
- How to use non-scale victories to stay motivated when the numbers won't budge
- Smart strategies to adapt your nutrition, movement, and habits as your body changes
If you've been wondering "what now?" after year one, this episode will give you the framework to tackle year two with confidence!
References
Ep 139: Why "Stopped Working" Is the Wrong Way to Think About GLP-1 Plateaus
Get Your FREE 3-Day Hunger Hormone Reset Mini Video Series
Join the January round of The 30/30 Program
Audio Stamps
00:30 - Introduction to what to expect in year two and beyond on GLP-1s, including the three essential shifts for long-term success.
01:45 - Shift #1: Moving from rapid to steady progress and learning to celebrate non-scale victories when the numbers slow down.
05:34 - Shift #2: Understanding metabolic adaptations and the ongoing adjustments needed for dose, movement, protein, and sleep.
09:24 - Shift #3: Moving into maintenance mode and building the "I do it anyway" identity where healthy habits happen no matter what.
10:50 - Recap of the three key mindset shifts needed for sustainable long-term success on GLP-1.
11:25 - Why maintenance is an active process that requires ongoing adjustments, just like maintaining a hotel or home over time.
13:55 - January 30/30 enrollment is now open with capped group size for optimal support.
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
Think You're a GLP-1 Non-Responder? Address These Key Issues First
Season 1 · Episode 79
lundi 12 août 2024 • Duration 19:30
Are you frustrated because your GLP-1 medication isn’t delivering the rapid results other people seem to achieve? It’s common to feel disappointed when your progress falls short of expectations. I know all too well the desire for that “magic” solution where all the challenges of obesity disappear overnight and you can achieve your goals effortlessly. Unfortunately, that’s not the reality for most people.
In this episode, I’ll dive into why some people experience slower results than others and clarify why terms like "non-responders" or "hypo-responders" might not be helpful if you haven't first addressed key lifestyle factors like hydration, protein intake, and sleep. Join me as I break down the numbers for successful weight loss with GLP-1 medications, share real-life insights into medication effectiveness, and offer practical advice on how to make the most out of your GLP-1 medication.
References
The Top 5 Mistakes That People Make When Starting a GLP-1
Ep. 69 - BMI: Proof it Falls Short as a Measure of Health
My Doctor Started Me on a GLP-1: Now What? Spotify Playlist
Audio Stamps
01:44 - Patients often feel frustrated with slow responses to anti-obesity medications because they aren't given clear expectations at the start.
04:00 - When starting GLP-1 medications, aiming for a 5% weight loss in 12 weeks ensures continued insurance coverage and effective results.
08:28 - Dr. Rentea shares the maximum percentage of total body weight to lose per week when starting GLP-1 medications like Wegovy or Ozempic.
10:45 - If you're not losing at least 5% of your body weight in the first 12 weeks on GLP-1 medications, Dr. Rentea advises you to evaluate key areas of your lifestyle and habits to improve results.
14:13 - Dr. Rentea shares an example of how convenient options can help maintain nutritional goals.
Quotes
“A lot of people think that they're going to start and it's just like fireworks and everything's going to be amazing.” - Matthea Rentea MD
“From a weight loss standpoint, on average we're going to look for at least 5 percent total body weight reduction within the first 12 weeks.” - Matthea Rentea MD
“The max percentage that we want you to lose total body weight per week would be 1%.” - Matthea Rentea MD
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
Why Getting Back on Track Feels Hard (And How to Make It Easier)
Season 1 · Episode 78
lundi 5 août 2024 • Duration 31:06
Today, we’re diving into a topic that hits home for me and many of my patients—getting “back on track.” I’m not a huge fan of this term because it implies everything has gone awry, which often isn’t the case. But there are definitely times throughout the year when certain areas aren't as optimal as they could be, and I need to refocus my efforts.
In this episode, we’ll take a positive psychology approach, encouraging you to focus on the healthy habits you’re still maintaining, even if you have drifted “off the wagon” a little bit. Plus, I’ll share the two essential things you need to do to successfully realign yourself with your goals. (Hint: it’s easier than you think!)
References
Register for The 30/30 Program Now!
Episode 74 - Low-Hanging Fruit: The Key to Breaking Fat Loss Plateaus
Audio Stamps
00:57 - Dr. Rentea shares a listener's review appreciating the podcast's real-world weight loss advice and positivity, which helps listeners mentally get back on track without feeling judged.
03:50 - We learn about the 30-30 Program, a four-week course focused on breaking old habits and embracing change to overcome weight loss plateaus. (Registration is now open, and the course starts on September 1st!)
08:00 - Dr. Rentea reminds us that getting back on track means building on what we've learned, rather than starting over completely.
12:50 - We hear Dr. Rentea’s personal experience of recently getting back on track.
15:36 - Dr. Rentea emphasizes that to get back on track, you need to keep things simple.
22:30 - We discover the power of setting a simple daily goal and using “bumper rails" to keep yourself aligned with your values and assess if your approach is working.
Quotes
“When you're not doing great, your first instinct is to entirely check out.” - Matthea Rentea MD
“The one thing that we just need to drop is that you're starting from the beginning.” - Matthea Rentea MD
“It feels so much better when I'm doing the things that I know really support me and help me.” - Matthea Rentea MD
“You need to keep it simple. You need to allow yourself to be able to actually get these things done.” - Matthea Rentea MD
“If you were to start the practice right now of asking yourself every single day, ‘What is my health goal?’, you would end up in a radically different place in life in a year or two from now.”
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
Stylist Secrets: Mastering Shapewear, “Trouble Zones”, and a Clutter-Free Closet with Lora LaPratt
Season 1 · Episode 77
lundi 29 juillet 2024 • Duration 49:11
Do you find yourself feeling uninspired by your closet each morning? You want to look stylish and feel good … but without all the effort? I was in the same position before I was introduced to today’s special guest, personal stylist Lora LaPratt. Like many of you, I believed a stylist wouldn’t be able to help someone in a larger body. But those assumptions could be holding you back from looking and, most importantly, FEELING amazing in your own style.
My goal with this podcast is to empower you to move beyond size and understand that your worth isn’t defined by it. That’s why I’m thrilled to welcome Lora to today’s show, to share her expert insights into creating a wardrobe that makes you feel confident and comfortable. Lora is committed to getting to know her clients personally and helping them express their unique style based on their interests, body shape, coloring, and lifestyle. She believes that comfort and happiness are the keys to great outfits, and she’s a big fan of high rise trousers! Ready to upgrade your closet game? Let’s dig in!
References
Register for The 30/30 Program Now!
Jockey shapewear
Audio Stamps
02:27 - Lora LaPratt shares her background as a personal stylist, helping clients of all sizes and budgets feel confident and their best every day.
06:45 - Dr. Rentea asks Lora what people should look for in a stylist to ensure they have a positive experience.
12:00 - Lora discusses her approach when clients are on a weight loss journey but are unsure about investing in themselves as their size might change.
15:09 - Lora shares the three most common trouble zones people face—stomach, arms, and thighs/hips—and offers tips for how to navigate these challenges.
23:15 - We hear Lora’s thoughts on Spanx and shapewear.
34:55 - We hear about Lora’s process for getting rid of clothes.
41:43 - Dr. Rentea explains how Lora transformed her travel experience by creating a personalized lookbook with outfit ideas.
Quotes
“It is overwhelming. And I take all of that scary stress out of it and just make it a really fun, enjoyable, but also renewing. I always say it's like a workout mentally and
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
Mastering Maintenance: 3 Strategies for Long-Term Success
Season 1 · Episode 76
lundi 22 juillet 2024 • Duration 15:17
We've all heard the saying, "Losing weight is easy, but keeping it off is hard," and it can feel pretty discouraging. If you've put in the hard work to transform your body and mindset, you might be worrying about how to tackle the maintenance phase. Should I stop or decrease my medication? What changes should I make to my routine?
In this episode, I break down what maintenance really looks like. We’ll cover three key areas: building a sustainable routine, using a "bumper rail" system for accountability, and making regular check-ins to stay on track. Plus, we’ll clarify how medication fits into your maintenance plan and when you might need to make changes. Join me now to feel confident about your next steps and learn how to keep your progress going strong!
Audio Stamps
00:57 - Dr. Rentea addresses one of the most frequently asked questions from patients about how to navigate the maintenance phase of treatment.
01:57 - We hear the importance of maintaining sustainable habits developed during weight loss and avoiding practices that are not enjoyable or sustainable long-term.
05:52 - Find out how a “bumper rail system” can help manage weight maintenance by effectively addressing small fluctuations.
07:52 - Maintenance requires ongoing effort and awareness. Dr. Rentea suggests regular check-ins and adjustments to stay on track.
09:43 - Dr. Rentea discusses medication strategies for weight maintenance.
Quotes
“What you're doing on the way down, you've got to keep doing it.” - Matthea Rentea MD
“The people that are successful long term, they're creating processes and systems, they're starting small scale enough, they keep adding things, and it's not a ton of effort. Otherwise they wouldn't keep doing it.” - Matthea Rentea MD
“For maintenance, you have to keep those things up. It might change the way in which you do it, but in some capacity you still need to do it.” - Matthea Rentea MD
“One of the things I really want to recommend is that you don't do things you're not willing to stick to.” - Matthea Rentea MD
“Our body gets smart to the changes that are happening. Just because you're in maintenance doesn't mean that there might not be more effort required at different times.” - Matthea Rentea MD
“There needs to be continued awareness. If you look at the national health registry, people that kept their weight off for 10 plus years are in some capacity tracking their weight.” - Matthea Rentea MD
“You've got to love what you're doing because you have to keep doing it and then be willing to switch it up a little bit.” - Matthea
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
Why You Binge and How to Stop with Jane Pilger
Season 1 · Episode 75
lundi 15 juillet 2024 • Duration 48:14
The most common type of eating disorder in the United States, binge eating disorder (BED) often triggers intense feelings of shame and thrives on secrecy. Jane Pilger understands firsthand the emotional and physical turmoil caused by BED—her first binge left her feeling broken and ashamed, marking the beginning of a cycle of overeating and restriction that lasted for over 25 years.
In this episode, Jane shares her personal journey of overcoming BED, showing that no matter how long you’ve struggled, you can learn the strategies, tools, and mindset you need to create peace and freedom with food. Drawing from her own recovery and extensive coaching experience, Jane digs into the 8 reasons why people binge eat, practical techniques to manage urges, and key strategies to promote the self-awareness and compassion that will help you heal your relationship with food.
References
Overcome Binge Eating with Powerful Questions:
The Binge Breakthrough Podcast
What is the difference between binge eating and overeating?
The Power of the Pause
Audio Stamps
02:34 - Jane shares her background and the reason she got into coaching around binge eating.
06:30 - Dr. Rentea asks Jane to explain the difference between binge eating and overeating.
11:40 - Jane talks through the eight primary reasons why people binge.
22:15 - We learn why Jane’s approach does not focus on eradicating binge eating altogether, but on separating the behavior from your self-worth.
31:38 - We find out about Jane’s "pause with permission" technique as a way to interrupt urges and calm the nervous system during moments of potential binge eating.
36:47 - Jane discusses how visualization can improve responses after binge-eating episodes
39:00 - We learn how binge eating often stems from various forms of disconnection and the key to overcoming this.
Quotes
“I have come to discover just how common binge eating is, but because there's so much shame, nobody is talking about it.” - Jane Pilger
“We can separate the behavior from you as a person. This isn't abou
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
Low-Hanging Fruit: The Key to Breaking Fat Loss Plateaus
Season 1 · Episode 74
lundi 8 juillet 2024 • Duration 24:13
Have you ever felt stuck in your weight loss journey, convinced that one particular issue is holding you back? Whether it's the late-night chocolate cravings or skipping workouts, many of us tend to fixate on the one issue we believe is the barrier to our progress. After coaching many people with this mindset, I've learned how crucial it is to take the blinkers off and identify all the other areas where you can make small improvements that will help you break through plateaus.
Think of it like picking apples in an orchard—you start with the ones within easy reach. Instead of aiming for the top of the tree, focus on the low-hanging fruit first. Simple changes such as increasing water intake, choosing better-quality foods, or enhancing your sleep routine can make a huge difference. If you're feeling stuck in your fat loss journey, stay tuned to learn how to make these manageable adjustments that will pave the way to achieving your goals.
References
Podcast Playlist: My Doctor Started Me On a GLP 1 and Now What?
Audio Stamps
01:22 - Instead of fixating on one problem, Dr. Rentea suggests exploring multiple areas for potential improvement when facing a fat loss plateau.
04:20 - Dr. Rentea challenges listeners to confirm if they are truly experiencing a plateau and, if so, to evaluate their readiness for further changes.
06:17 - Listeners find out about a practical task to help them rethink health challenges and identify new ways to make improvements.
11:05 - Dr. Rentea reminds us that implementation of new strategies isn't always easy, comparing it to a recent experience in her business. Persistence and adaptation is key.
12:35 - Dr. Rentea discusses key areas to focus on for optimizing health including hydration, nutrition, movement, sleep quality, and stress management.
Quotes
“Do you actually have the mental capacity to do more right now? Because we're going to have to change something.” - Dr. Rentea
“Anytime you want to break a habit, you want to do something different, you want to switch up your routine in some way, it's going to be an energy expenditure.” - Dr. Rentea
“There is always more that you can do.” - Dr. Rentea
"These things start to add up and they matter with time. If you make the bar low enough, the lowest hanging fruit, you will actually take action on it." - Dr. Rentea
“I'm going to have a brainstorming session and write down all the things I can do. Then I'm going to figure out what's actually easy on that list and I'm going to
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.
The 30/30 Program is live for Enrollment now!
mardi 2 juillet 2024 • Duration 14:37
Enroll in The 30/30 Program now! Registration closes August 31st 11:59pm EST.
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.
If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.









