The Metabolic Link β Details, episodes & analysis
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The Metabolic Link
Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field
Frequency: 1 episode/13d. Total Eps: 97

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Dr. Nina Teicholz | America's Metabolic Decline: The High-Cost of Low Fat | The Metabolic Link Ep 80
Episode 80
mardi 4 novembre 2025 β’ Duration 01:05:43
For over fifty years, Americans have been told that cutting fat was the key to better health. Yet after decades of low-fat guidelines, rates of obesity, diabetes, and metabolic dysfunction have skyrocketed - now affecting more than 88% of the population.
In this episode of The Metabolic Link, Victoria Field sits down with Dr. Nina Teicholz, science journalist and author of The Big Fat Surprise, whose decade-long investigation into nutrition science uncovered how flawed evidence and policy decisions shaped the way we eat. Her research reveals a troubling gap between the science and the guidelines meant to protect public health.
Answered in this episode:
- How did you transition from investigative journalism into becoming one of the leading voices challenging nutrition policy?
- What specifically makes the original science behind the low-fat diet hypothesis so weak?
- How did Ancel Keys' controversial research become official U.S. nutrition policy?
- What were the metabolic consequences when Americans replaced dietary fat with carbohydrates?
- How did seed oils come to dominate the American food supply, and what are the metabolic implications?
- What do randomized controlled trials reveal about low-carb versus low-fat diets for metabolic health?
- How has industry funding influenced the direction of nutrition research and policy?
This conversation provides a rigorous examination of how weak associational data became entrenched policy, the metabolic consequences of replacing saturated fats with refined carbohydrates and seed oils, and what the path forward looks like for evidence-based nutrition science.
More of Dr. Teicholz:
- Unsettled Science on Substack
- The Nutrition Coalition
- The Big Fat Surprise
- X.com
Big thanks to our sponsors:
β
Genova Connect β Get 15% off any test kit with code METABOLICLINK here!
β
Fatty15 β Get 15% off a 90-day Starter Kit with code METABOLICLINK here.
β
ZocDoc - Find and instantly book a top-rated doctor here.
β
Cowboy Colostrum - Get 25% off when you use code METABOLICLINK at checkout!
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Metabolic Therapy for Pets: The Future of Veterinary Medicine | Dr. Loren Nations | The Metabolic Link Ep. 79
Episode 79
mardi 21 octobre 2025 β’ Duration 01:09:01
When veterinarian Dr. Loren Nations lost his wife to aggressive cancer despite the best conventional treatments, he didn't just grieveβhe revolutionized his entire approach to medicine. In this deeply personal conversation, Dr. Nations reveals how tragedy led him to discover that our pets are experiencing metabolic disease at rates even higher than humans, with 61% of cats and 59% of dogs now obese.
Dr. Loren Nations is a board-certified veterinarian with over 30 years of experience. He's the founder of Veterinary Healthcare Associates, Ascend Vets, and Neoterric, pioneering the integration of ketogenic nutrition, hyperbaric oxygen therapy, and metabolic medicine into veterinary care.
Questions Answered in This Episode:
- What metabolic-based therapies are you using alongside standard care, and which have proven most effective?
- Can dogs and cats safely eat ketogenic diets without developing pancreatitis?
- How do you approach gut healing in pets, and what specific strategies or supplements do you use beyond nutrition?
- What happens when you treat pet cancer with metabolic therapies instead of just conventional oncology?
- What can veterinary medicine teach us about human metabolic health?
This conversation bridges two worlds we rarely see connectedβshowing how the metabolic principles transforming human health apply equally to our animal companions, and how healing our pets might just teach us to heal ourselves.
Join us on November 12th for a live Q&A with Dr. Nations on The Metabolic Initiative.
Dr. Nations also has a full presentation available for on demand viewing on our medical education platform titled βMetabolic Health for Our Petsβ for those ready to dive deeper into metabolic therapy for their companions. Watch now with a free trial here.
Neoterric: Find Dr. Nations' online education for pet parents here.
Veterinary Healthcare Associates: Learn about Dr. Nations' animal hospital here.
KetoPet: Read scientific articles on the ketogenic diet for pets here.
Special thanks to the sponsors of this episode:
β
Genova Connect β Get 15% off any test kit with code METABOLICLINK here!
β
iRestore - Get a huge discount on the iRestore Illumina Face Mask when you use the code METABOLICLINK here
β
Piquelife.com - Get the Pu'er Bundle for 20% off here.
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
The Great Obesity Debate: Energy Balance vs Fructose - Dr. Layne Norton & Dr. Richard Johnson | Ep.70
Episode 70
mercredi 25 juin 2025 β’ Duration 01:42:46
Whatβs really causing Americaβs obesity epidemic? In this special debate episode of The Metabolic Link, two leading voices in metabolic health square off: Dr. Richard Johnson, renowned for his research on fructose metabolism, and Dr. Layne Norton, a PhD in nutritional sciences and expert on the energy balance model.
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Moderated by host Dr. Dominic DβAgostino, the discussion dives deep into the biological roots of obesity, the relevance of sugar-sweetened beverages, the role of leptin and uric acid, and whether itβs fructose or calories that are driving the crisis. Despite their differing perspectives, both experts agree on one critical pointβour modern food environment is fueling metabolic dysfunction on a massive scale.
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This is one of the most nuanced and constructive conversations youβll hear on the topic of obesity science.
References submitted by both guests can be found here!
For more exclusive interviews and presentations with Dr. Johnson and Dr. Norton along with 100s of other videos on metabolic health and therapy, ad-free private episodes of The Metabolic Link, and to earn CMEs visit our member medical education platform: https://membership.metabolicinitiative.com
Special thanks to the sponsors of this episode:
β
Genova Connect β Get 15% off any test kit with code METABOLICLINK here
β
iRestore β Get a huge discount when you use the code METABOLICLINK here
β
Fatty15 β Get 15% off a 90-day Starter Kit with code METABOLICLINK here
Learn more about Dr. Layne Norton
Learn more about Dr. Richard Johnson
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
How Could an Animal-Based Diet Impact Metabolic Health? | Anthony Chaffee, MD | The Metabolic Link Ep.69
Episode 69
mardi 10 juin 2025 β’ Duration 01:29:03
Join us for a Live Q&A on June 18th at 9am PT/12pm ET with Dr. Anthony Chaffee and also enjoy ad-free exclusive episodes, videos covering the latest science on metabolic health on therapy, and earn CMEs by clicking here.
In this episode, Dr. Anthony Chaffeeβmedical doctor, neurosurgical registrar, and nutrition educatorβjoins Dr. Dominic DβAgostino for a thoughtful exploration of the scientific rationale behind animal-based ketogenic diets.
Together, they discuss burgeoning interest in how this approach could support metabolic health, reduce inflammation, and potentially improve outcomes in chronic conditions. Dr. Chaffee also shares his personal journey, evolutionary insights, and emerging clinical cases that invite a reexamination of modern dietary assumptions.
Whether youβre a practitioner, patient, or simply curious about low-carb, ketogenic, or elimination-based nutrition strategies, this conversation offers valuable perspective on food, metabolism, and human health.
Special thanks to the sponsors of this episode:
β
Genova Connect β Get 15% off any test kit with code METABOLICLINK here
β
Fatty15 β Get 15% off a 90-day Starter Kit with the code METABOLICLINK here
β
Zocdoc β Find and instantly book a top-rated doctor here
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Bipolar Illness & Metabolic Health: My Story | Matt Baszucki | The Metabolic Link Ep.68
Episode 68
mercredi 28 mai 2025 β’ Duration 38:41
In this deeply personal and courageous episode of The Metabolic Link, we hear from patient advocate and podcast co-host Matt Baszucki, who shares how he enduredβand ultimately overcameβtype 1 bipolar disorder through a radical shift in treatment: ketogenic metabolic therapy.
After years of hospitalizations, debilitating mood episodes, and failed conventional treatments, Matt found hope through the emerging field of metabolic psychiatry. With the help of his family, including support and clinical guidance from Dr. Christopher Palmer, Matt adopted a therapeutic ketogenic diet in 2021βand the results were extraordinary.
Now a thriving project manager in Silicon Valley and co-host of The BipolarCast, Matt is helping drive a movement that challenges the very foundation of how we treat mental illness. This episode is not just about recoveryβit's about transformation, resilience, and the future of mental health care.
Special thanks to the sponsors of this episode:
β
Genova Connect β Get 15% off any test kit with code METABOLICLINK here
β
iRestore β Get a huge discount when you use the code METABOLICLINK here
Watch Matt Baszucki's YouTube Channel here and Bipolar Cast here. Learn more about the non-profit, Metabolic Mind, here.Β
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Hormone Health for Performance and Longevity | Kyle Gillett, MD | The Metabolic Link Ep.67
Episode 67
mardi 6 mai 2025 β’ Duration 54:11
Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here!
If youβre a clinician, scientist, or anyone interested in taking a deep dive into the complexities of hormone regulation, this episode of The Metabolic Link Podcast is for you! Recorded live at Metabolic Health Summit 2024, this in-depth presentation by Dr. Kyle Gillettβdual board-certified in family and obesity medicineβdives deep into the biochemical, clinical, and therapeutic layers of hormone health.
From his foundational βSeven Pillars of Healthβ to cutting-edge insights on peptides, receptor affinity, and hormone testing strategies, Dr. Gillett provides a masterclass on optimizing hormones for performance, longevity, and metabolic resilience. Designed for professionals and educated listeners alike, this talk bridges clinical relevance with scientific nuance.
Access even more from Dr. Gillettβlike his exclusive Hormones 101 lectureβinside our medical education platform, The Metabolic Initiative. Start your free trial at https://membership.metabolicinitiative.com.
Special thanks to the sponsors of this episode:
β
Genova Connect β Get 15% off any test kit with code METABOLICLINK here
β
Fatty15 β Get 15% off a 90-day Starter Kit with the code METABOLICLINK here
β
Zocdoc β Find and instantly book a top-rated doctor here
β
Puori β Get 20% off supplements with code METABOLICLINK here
Learn more about Dr. Gillett here!
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Journal Club: The Rise of Fatty Liver Disease and its Metabolic Roots | Ep.66
Episode 66
mercredi 23 avril 2025 β’ Duration 58:56
Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com
In today's journal club episode, co-hosts of The Metabolic Link, Dr. Angela Poff and Dr. Dominic D'Agostino, unpack the startling rise of non-alcoholic fatty liver disease (NAFLD)βa silent epidemic affecting millions worldwide. Tune in as they break down groundbreaking new research revealing how NAFLD isn't just impacting adults, but alarmingly, children and adolescents too.
You'll learn about the latest updates in terminology, such as Metabolic Dysfunction Associated Steatohepatitis (MASH) and Metabolic Dysfunction Associated Steatotic Fatty Liver Disease (MASLD), highlighting a critical connection to underlying metabolic dysfunction. Plus, discover exciting dietary strategiesβlike therapeutic carbohydrate restrictionβthat hold potential not just to prevent, but to actually reverse liver fat accumulation.
If you've ever wondered how your diet and lifestyle choices directly shape your metabolic health, this episode delivers practical insights and actionable information straight from cutting-edge science. Don't miss this deep dive into the latest science on NAFLDβand how simple shifts today could dramatically improve your metabolic health tomorrow.
Special thanks to the sponsors of this episode:
- Genova Connect β Get 15% off any test kit with code METABOLICLINK here
- Maui Nui Venison: Gain access to a limited collection of our favorite Maui Nui products here
- iRestore: Use code METABOLICLINK for exclusive discounts on the iRestore Illumina Face Mask hereΒ
- Puori β Get 20% off supplements with code METABOLICLINK here
Read the papers discussed here:Β
- https://pubmed.ncbi.nlm.nih.gov/38521116/Β
- https://pubmed.ncbi.nlm.nih.gov/38914224/
- https://pubmed.ncbi.nlm.nih.gov/38771552/
- https://pubmed.ncbi.nlm.nih.gov/38723301/Β
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
The Metabolic Impact of GLP-1s on Obesity | Spencer Nadolsky, DO | Ep.65
Episode 65
vendredi 11 avril 2025 β’ Duration 59:37
Join us for a FREE Live Q&A with Dr. Spencer Nadolsky on April 22nd at 9am PT / 12pm ET! Your first seven days are free, and as a member of The Metabolic Initiative, youβll gain access to exclusive, ad-free episodes, hundreds of expert-led videos on metabolic health and therapy, CME opportunities, and more here!
In this episode of The Metabolic Link, Dr. Dominic DβAgostino sits down with Dr. Spencer Nadolskyβboard-certified obesity and lipid specialist, former NCAA heavyweight wrestler, and founder of Vineyardβto explore one of the most hotly debated and often misunderstood tools in modern medicine: GLP-1 receptor agonists.
Together, they take a deep dive into how these drugs work, who theyβre for, and why they might not always be a magic bullet. Dr. Nadolsky shares clinical insights into the real-world use of semaglutide, tirzepatide, and combination therapies, breaking down everything from appetite regulation and side effects to muscle loss, mood changes, and the potential future of prevention.
They also tackle pediatric obesity, long-term use vs. off-ramping, and the critical role of resistance training and nutrition for protecting muscle mass while on these medications.
Special thanks to the sponsors of this episode:
β
Genova Connect β Get 15% off any test kit with code METABOLICLINK here
β
Fatty15 β Get 15% off a 90-day Starter Kit here (use code METABOLICLINK)
β
Zocdoc β Find and instantly book a top-rated doctor here
β
Puori β Get 20% off supplements with code METABOLICLINK here
π§ Learn more about Dr. Nadolsky β drspencer.com
π₯ Donβt forget to RSVP for the live Q&A on April 22!
ποΈ membership.metabolicinitiative.com/drspencer
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Reversing Heart Disease Through Metabolic Health | Philip Ovadia, MD | Ep.64
Episode 64
mardi 25 mars 2025 β’ Duration 01:06:34
Join us for a Live Q&A with Dr. Ovadia on March 31st at 12 PM PT / 3 PM ET! Your first seven days are free, and as a member of The Metabolic Initiative, youβll gain access to exclusive, ad-free episodes, hundreds of videos on metabolic health (including Dr. Ovadiaβs presentation, Fanning the Flames: Inflammation, Insulin Resistance, and Heart Disease), CME opportunities, and more. Register here!
Dr. Philip Ovadia is a cardiac surgeon on a mission to change how we think about heart disease. After performing thousands of surgeries, he realized that most of his patients didnβt need to end up on his operating table in the first place. In this episode, Dr. Ovadia joins host Victoria Field to uncover the metabolic factors driving heart disease and explore how we can prevent it before it requires surgery.
They dive into key topics like the role of insulin resistance versus cholesterol, why he says inflammation should be a bigger focus than LDL, the importance of advanced testing like Coronary Artery Calcium Score scans, and why lifestyle changes are the true foundation of prevention. Dr. Ovadia also shares his personal journey from obesity to metabolic health and how it reshaped his entire approach to medicine.
Whether you're a patient, physician, or anyone passionate about heart health, this episode will give you the tools you need to avoid the operating table.
Special thanks to the sponsors of this episode:
β
Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK here
β
Maui Nui Venison: Gain access to a limited collection of our favorite Maui Nui products here
β
Zocdoc: Visit this link to find and instantly book a top-rated doctor
β
Puori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Visit this link and use the code METABOLICLINK
Learn more about Dr. Ovadia here!
Join our Live Q&A with Dr. Ovadia: https://membership.metabolicinitiative.com/ovadiaΒ
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
The Mitochondrial Link to Mental Illness | Ana Andreazza, PhD | The Metabolic Link Ep.63
Episode 63
mardi 11 mars 2025 β’ Duration 01:04:32
Mitochondria do more than power our cellsβthey may hold the key to understanding and treating mental illness.
In this episode of The Metabolic Link, Dr. Dominic DβAgostino sits down with Dr. Ana Andreazza, a leading expert in mitochondrial health at the University of Toronto.
Dr. Andreazza has pioneered research linking mitochondrial dysfunction to psychiatric disorders like bipolar disorder, utilizing groundbreaking 3D brain organoid models to study neurotransmission. She also leads research on mitochondrial transplantation, a potential game-changer in regenerative medicine.
Join us as we explore how mitochondria influence mood, metabolism, and overall healthβand why optimizing mitochondrial function may be the future of medicine. Listen to the episode on any major podcast player or watch the interview on YouTube.
Learn more about Dr. Andreazza's work here.
Special thanks to our sponsors:
- Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK here
- Fatty15: Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK here
- MUD/WTR: Start your new morning ritual & get up to 43% off your MUDWTR with code METABOLICLINK here
- Puori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Visit this link and use the code METABOLICLINK here
In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!
You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!
Find us on social:Β
Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.









