The Joe Cohen Show – Details, episodes & analysis

In this special "Best of Season 7" episode, we’re revisiting the most impactful, inspiring, and thought-provoking moments from our standout interviews this season. From groundbreaking health hacks and personal growth strategies to expert insights on optimizing your life, these are the clips that sparked the biggest conversations. Whether you're a long-time listener or new to the show, this episode is packed with must-hear wisdom from our incredible guests. Tune in for a quick recap of what made Season 7 unforgettable!

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In this episode Joe sits down with Jack Smith, known for his pioneering biohacking experiments.

Jack shares his biohacking journey, highlighting unique health devices like the Pulse PEMF machine, EES cube, Altwork desk, and Oura Ring. 

He also delves into therapies such as ketamine for mental wellness, GAINSWave, and resistant starch for gut health. 

Through discussions on neurofeedback, silent retreats, and advanced wellness practices, Jack underscores his dedication to health optimization techniques and consistent lab testing.

You can follow his ongoing experiments on X @_jacksmith

Interested in joining the upcoming AIWO retreat? Click here to schedule a call.

- Check out SelfDecode: https://selfdecode.com/

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This is the first episode of a three-part series with Elizma Lambert, where we delve into the world of the Organic Acids Test (OAT) and its crucial role in optimizing health.

In this episode, we get started on our analysis of Organic Acids Test (OAT) and its essential role in naturopathic medicine and precision health. 

Elizma Lambert, a seasoned expert with over 20 years of experience, discusses the legitimacy and applications of functional health tests, especially the OAT test. 

First, we specifically look at fungal infections like Candida, and look at how these tests diagnose complex conditions by examining the intricate relationships with symptoms and signals. 

We'll explore the benefits of a holistic approach to health, moving beyond quick fixes to address genetic predispositions through multi-dimensional health strategies. 

Find out what’s in Joe’s mood toolkit! Joe Cohen has been doing health experiments on himself for over 20 years, and he’s finally sharing all his knowledge with you.

In this episode, Joe walks you through lifestyle changes and 3 of his favorite supplements for mood: 5-HTP, thiamine, and resistant starch & butyrate. He discusses his megadosing experiments, dosages, and his problem with the RDA.

He explains why he takes each supplement, the mechanisms of action of these supplements, and the effects they have on his mood. Plus, discover the one problem Joe has with resistant starch.

Find out how Joe determines if he’s deficient in a nutrient, and the importance of learning your genetic predispositions and tracking your labs when building your regimen.

Learn all about Joe’s favorite mood stabilizer supplements!

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Have you heard of scientific wellness? In this episode, Nathan Price and Joe discuss whether the conventional approach of using pharmaceuticals to treat chronic diseases is effective, or if a preventative approach to complex conditions such as cardiovascular disease and Alzheimer’s is the best choice.

Nathan explains how genes can help predict the success of lifestyle-based interventions and talks about the accuracy of polygenic risk scores vs single variants for disease prediction, and how genetics can be used in healthcare.

Nathan and Joe also talk about nicotinamide mononucleotide (NMN), nicotinamide riboside (NR), DHEA, and other supplements. Plus, Nathan explains the controversy of choline, carnitine, and TMAO, and if you should be worried.

Dr. Nathan Price is the Chief Scientific Officer of Thorne HealthTech and author of The Age of Scientific Wellness. He was named one of the 10 Emerging Leaders in Health and Medicine by the National Academy of Medicine and was appointed to the Board on Life Sciences of the National Academies of Sciences, Engineering, and Medicine.

- Preorder The Age of Scientific Wellness

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Should you be scared of psychedelics? In this episode, Tim Gray and Joe talk about how to get more REM and deep sleep, and Tim discusses his experience with methylene blue. They talk about the pros and cons of alcohol and their experience with different psychedelics.

Tim shares his experience with conventional medicine, the top things he’s trying to optimize in his health and his strategies for kidney health, gut health, and more. He talks about how he used to track 35 biomarkers every day, and which ones he still continues to monitor.

They discuss methylation, the MTHFR gene & SNPs, and how genetics and your environment can affect your overall health and how you respond to supplements.

Tim Gray is the UK’s leading biohacker and the founder of the popular Health Optimisation Summit, The Biohacker London Meetup group, and London’s first private Hyperbaric Oxygen Clinic. He is dedicated health optimizing biohacker, a psychology specialist, entrepreneur, and global speaker.

- Check out the Health Optimisation Summit (Use code SELFDECODE for 10% off your ticket)

- Find Tim on Instagram

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Are supplements a waste of time and money? In this episode, Shawn Wells and Joe discuss whether taking supplements every day is bad for your health, and Joe shares the one time a supplement caused his liver enzymes to spike (it’s not what you’d expect!).

Shawn talks about the problem with certain supplement companies and lets you in on important things to look out for when choosing a supplement. They talk about all kinds of supplements, including lipoic acid, dihydroberberine, paraxanthine, ergothioneine, NAD, and more, discussing their effects, dosages, and how they work in the body.

Shawn and Joe also discuss the importance of optimal mitochondria function and why you should pay attention to it, and Shawn shares his ultimate mitochondrial supplement stack.

Shawn Wells, MPH, LDN, RD, CISSN, FISSN, is the world’s leading nutrition biochemist and an expert on health optimization. He’s formulated over 700 supplements, foods, and beverages, and is the author of The Energy Formula.

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Do supplements work the same for everyone? In this episode, Lucas Aoun shares his favorite supplements to improve cognitive function and focus, and he and Joe dig deep into how these compounds work in the body, discussing the research, dosages, and what to look out for.

They discuss dopamine and the mechanisms behind dopamine supplements and share their different experiences experimenting with supplements. Plus, listen to the benefits of increasing dopamine levels steadily vs taking supplements that cause a spike.

Lucas and Joe also talk about how to optimize testosterone levels, what causes low testosterone, and Lucas shares one surprising hack to increase your testosterone levels. Plus, find out one health hack Joe coins as “bromeopathy”.

Lucas Aoun is the founder of Ergogenic Health and Australia's leading biohacker & men's health expert.

This interview is not intended as medical advice.

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Low carb? Keto? Low fat? Fasting? In this episode, Katie Wells and Joe talk about her experience with dieting, some of the benefits she gets from intermittent fasting, and they discuss the controversial topic of cholesterol (spoiler: lower is not necessarily better).

Katie shares some of her favorite health hacks, and they talk about how genetics can influence a person’s health and how to use this information to live optimally. They also discuss which and how to track labs, the importance of optimal vs normal ranges, and what Katie does to hack her sleep & mood.

Katie Wells is the founder and CEO of wellnessmama.com and wellnesse.com. A mom of 6, she took her health into her own hands and started researching to find the answers to her health struggles. She has written over 1,500 blog posts, 3 books, and was named one of the most influential people in health and wellness.

This interview is not intended as medical advice.

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Timestamps:

(0:00) - Introduction

(1:04) - How Katie got into health

(3:53) - The Personalized Health Podcast?

(4:57) - Shifting of health goals

(6:44) - Katie’s current health goals

(8:14) - Joe shares his health journey

(9:04) - What labs to track for anti-aging?

(10:32) - Alcohol and saturated fats affect on health

(12:31) - Katie Wells thoughts on LDL cholesterol

(13:24) - Over-dieting and under nourishing

(16:52) - Unsullied by paid sponsors

(17:18) - Megadosing and metabolic flexibility

(18:45) - Katies daily supplement intake & fasting

(20:01) - The mental and spiritual benefits of a long fast

(22:15) - Joe’s experience with fasting

(23:42) - What supplements does Katie take now?

(24:39) - Pregnenolone dosages & benefits

(25:40) - Nootropic stack for focus

(26:37) - Tips to improve sleep from Katie

(28:45) - Katie’s most successful health “experiments”

(30:09) - The importance of protein in your diet

(31:40) - The last time Katie changed her mind about a health topic

(32:42) - The best health hack Katie wished she found earlier

(34:52) - Katie’s top hacks to optimize mood

(36:36) - The difference between normal and optimal lab ranges

(37:45) - How using SelfDecode can help optimize your lab levels

(38:58) - The most interesting DNA discovery

(41:10) - Katie’s expectations on her life span

(43:15) - Characteristics that make you successful

Is high cholesterol really bad for you? In this episode, Joe and Siim Land discuss what causes high cholesterol, which biomarkers to track for longevity, and the biggest mistake people make when trying to lose weight.

Siim shares one surprising mineral that can help lower cholesterol and talks about how intermittent fasting helps his mental & physical performance. Then, Siim and Joe discuss a top supplement for longevity and healthspan.

Siim Land is a renowned public speaker and expert in biohacking, health optimization, and overall performance optimization. He is also the author of Metabolic Autophagy and The Immunity Fix with Dr. James Dinicolantonio.

This interview is not intended as medical advice.

- Check out SelfDecode

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Timestamps:

(0:00) - Introduction

(0:41) - Why Siim Got Into Biohacking

(2:35) - What markers should you measure for longevity?

(8:28) - Taking blood tests every year to track improvements

(10:40) - The top supplement to improve longevity

(13:21) - Unsullied by paid sponsors

(13:47) - Cholesterol in the biohacking world

(14:49) - Intermittent fasting, fats, and lowering cholesterol

(17:30) - Zinc and Copper ratio

(18:53) - Does lower T3 contribute to high cholesterol?

(20:03) - One supplement with high evidence of increasing lifespan

(21:00) - What Siim tracks on a regular basis

(23:09) - Siim’s HRV numbers

(24:20) - How Siim improves mental performance

(26:51) - How Siim improves physical performance

(30:35) - The biggest mistake people make with fat loss

(35:21) - Genetics affect on portion control in diets

(37:06) - How often is Siim physically active per day?

(38:31) - How you process carbs differently based on your body composition

(41:00) - Sleephacking tips from Siim Land

(46:20) - Improving your immunity