The Analytical Wavelength – Details, episodes & analysis

In this episode, ACD/Labs Senior Director of Technical and Scientific Services, Karim Kassam joins hosts Jesse and Bally to dive deeper into the importance of ionization. He gives us some insight into the tools available to help accurately predict pKa along with some hints and tips to help improve accuracy in predictions.  

Read more about the importance of ionization in pharmaceutical R&D in this blog post: The Importance of Ionization in Pharmaceutical R&D - ACD/Labs (acdlabs.com) 

Find out how a deeper understanding of ionization can help improve chromatographic separations in this blog post: Improve Chromatographic Separations: Consider Mobile Phase pH & Analyte pKa - ACD/Labs (acdlabs.com) 

MilliporeSigma’s new online digital reference platform, Chemistwin® is a trail blazing digital tool to accelerate workflows in the analytical laboratory.     

In this episode, ChemisTwin® Project Lead Coralie Leonard and R&D Scientist Albert Farre Perez join hosts Sarah and Bally to dive deeper into the driving factors of MilliporeSigma’s reference material business transformation process. They also give us a glimpse into the first version of the platform, and how it will progress to reshape the world of analytical testing. 

Watch Coralie’s presentation from the Driving Efficiencies with Spectrus Virtual Symposium: https://www.acdlabs.com/resource/revolutionizing-chemistry-by-digitalizing-analysis-controls/ 

ChemisTwin trial registration: www.sigmaaldrich.com/ChemisTwin 

Learn more about ACD/Labs: https://www.acdlabs.com/

ACD/Labs prides itself in offering our users vendor-neutral tools that allow them to use our software with almost any analytical instrument. For us, that means we need to work closely with many partner organisations to ensure we are compatible with the latest data formats. In this episode, we are talking with Graham McGibbon to learn how great partnerships are forged and maintained.

Reach out to Graham: graham.mcgibbon@acdlabs (dot) com

Sign-up for the Webinar: https://theanalyticalscientist.videomarketingplatform.co/how-to-overcome-the-challenges-of?

Brought to you by ACD/Labs: www.acdlabs.com

At ACD/Labs, we have a unique view of everything happening in the world of chemistry. Our customers include many of the top pharmaceutical, chemical companies in the world, as well as top research institutes and government agencies. That means we are dedicated to understanding the workflows and data flows of scientists from around the world.

With 2022 drawing to a close, we thought it would be a great opportunity to share some of that perspective with our audience. Mark Meyers is the VP of sales, which means he is always trying to anticipate the needs of our customers. Hear what trends he is following going into 2023.

Link to CAS announcement: https://www.acdlabs.com/resource/cas-and-acd-labs-collaborate-to-provide-predictive-insights-to-scientists/

Brought to you by ACD/Labs: www.acdlabs.com

Regulations regarding chemical software and data can be intimidating. What is software validation? How does that relate to Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP)? It all begins to sound like legal mumbo jumbo.

Luckily, we can help demystify GXP. Dr. Karim Kassam has helped many clients implement ACD/Labs software in regulated environments. In this episode, he will answer common questions about how these different forms of regulation fit together.

Brought to you by ACD/Labs: www.acdlabs.com

The last couple of years have been extremely disruptive. Covid-19 even influenced the world of chemistry - scientists changed the way they worked, and conferences moved online.

With conferences and trade shows coming back, now is the perfect time to check-in on the field of NMR. Are things returning to normal, or have we shifted to a new normal?

Dimitris Argyropoulos and Mary McKee join the podcast to share their experiences at SMASH. They provide insights about the evolving role of conferences, and the direction of NMR research.

Learn more about NMR products from ACD/Labs: https://www.acdlabs.com/solutions/nmr-spectroscopy/

Brought to you by ACD/Labs: www.acdlabs.com

Excel plays a critical role in research and development. Everyone from undergraduate students to elite pharmaceutical chemists relies on the program to process, analyze, and store their data. Unfortunately, spreadsheets are not designed to work with chemical information or support collaborative workflows. What’s the alternative?

Season 3 of the Analytical Wavelength brings unique perspectives from our team of experts who are working at the frontier of chemistry. In this episode, we talk to Application Scientist Alex Waked about his peer-reviewed paper “Consolidating and Managing Data for Drug Development within a Pharmaceutical Laboratory” that discusses data management issues in pharmaceutical development.

Listen, and learn how chemical development researchers can overcome Excel’s data management issues.

Read the OPRD paper: https://pubs.acs.org/doi/10.1021/acs.oprd.1c00082

Learn more about Luminata: https://www.acdlabs.com/products/spectrus-platform/luminata/

Brought to you by ACD/Labs: www.acdlabs.com

Our experts at ACD/Labs spend their days working with the best and brightest in the pharmaceutical and chemical industries. For season 3 of the Analytical Wavelength, we wanted to feature members of our team so they could share their unique perspectives on the trends and science and technology. Look forward to new episodes starting in September.

Until then, we wanted to share something extra for our loyal listeners. In February 2022, AstraZeneca’s Dr. Andrew Teasdale presented at the ACD/Labs Impurities and Contaminants Virtual Symposium. His talk on n-nitrosamines control was fascinating, and we wanted to share it with you.

More presentations from the Impurities and Contaminants Symposium can be found here:

https://www.acdlabs.com/resources/resources-library/?_resource_search=impurities&_resource_content_type=webinar

Hosts:

Jesse Harris

Sarah Srokosz

Brought to you by ACD/Labs: www.acdlabs.com

AI-assisted drug discovery is all the rage these days. It seems as if new companies and partnerships are being announced every day. Is this a new phenomenon, or an evolution of what has been done in the past? What are the key challenges standing in the way of computer-assisted drug discovery?

For the last episode of season 2 of the analytical wavelength we talk with two experts in drug discovery. Dr. Chris Lipinski is famous for introducing the "Lipinski Rule of 5s," the original prediction tool in drug discovery, which he developed at Pfizer. Dr. Olivier Elemento is a professor at Cornell University, where he studies AI-assisted drug discovery

More information about Percepta: https://www.acdlabs.com/products/percepta/index.php

Hosts:

Jesse Harris

Charis Lam

Brought to you by ACD/Labs: www.acdlabs.com

Chromatography is a powerful a flexible technique at all stages of chemistry research. Whether you are a graduate student attempting purify a compound or a pharmaceutical company attempting to test product quality, an effective chromatographic method is critical.

But how do you develop these methods? Optimizing chromatography techniques is notoriously time consuming and frustrating work. Can predictive software increase the productivity of chromatographers?

Learn more about chromatography software from ACD/Labs: https://www.acdlabs.com/products/com_iden/meth_dev/autochrom/

Hosts:
 
Jesse Harris
Charis Lam

Guests:

Dr. Scott Van Bramer
Dr. Justin Shearer