Ophthalmology Journal – Details, episodes & analysis

The RID-MyC assay, a CRISPR/Cas12a-based test, offers swift and reliable detection of Fungal Keratitis, enhancing diagnostic capabilities at point-of-care settings. Dr. Rajesh Rao interviews Dr. Siddharth Narendran on the development of this assay from his Ophthalmology Science article, “Development and Clinical Evaluation of a CRISPR/Cas12a-Based Nucleic Acid Detection Platform for the Diagnosis of Keratomycoses.”

Development and Clinical Evaluation of a CRISPR/Cas12a-Based Nucleic Acid Detection Platform for the Diagnosis of Keratomycoses. Deivarajan, Hanith Raj et al. Ophthalmology Science, Volume 4, Issue 5.

Join Ophthalmology’s Editor-in-Chief, Russell Van Gelder, as he presents “The Year in Literature: Editor’s Choice Highlights From the Ophthalmology Journal Family”  in Chicago at AAO 2024 on Sunday October 20, 2024, at 2pm local time in McCormick Place South Building Room S406A. Search “SYM48” in the Mobile Meeting Guide for more information.

Dr. Matt Feng is joined by Dr. Thomas H. Dohlman to discuss the effectiveness of topical and subconjunctival bevacizumab in suppressing vascularization in graft and host bed after high-risk corneal transplantation, from his Ophthalmology Science article “Suppression of Neovascularization by Topical and Subconjunctival Bevacizumab After High-Risk Corneal Transplantation”

Suppression of Neovascularization by Topical and Subconjunctival Bevacizumab After High-Risk Corneal Transplantation. Dohlman, Thomas H. et al. Ophthalmology Science, Volume 4, Issue 4.

Scleral buckling is a common surgical procedure for the repair of rhegmatogenous retinal detachment. The association between scleral buckling and angle-closure glaucoma is well-documented. However,the influence of scleral buckling on the development and progression of open-angle glaucoma is less well understood.

Dr. Lori Provencher interviews Dr. Arthur J. Sit on the effect of scleral buckle surgery on ocular biomechanics and aqueous humor dynamics from his Ophthalmology Glaucoma article, “The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics.”

The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics. Lyons, Lance J. et al. Ophthalmology Glaucoma, Volume 7, Issue 1, 1 – 7.

The Ophthalmology-family of journals is now on Instagram. Follow @aaojournal for clinical images, research articles, news, editorials, podcasts, and more!

Neuro-ophthalmology consultations are critical to the diagnosis and management in the hospital setting. Prompt consultation prevents diagnostic errors and improves patient outcomes. The scarcity of neuro-ophthalmologists means that the increasing outpatient demand cannot be met, prompting many emergency department referrals by non–neuro-ophthalmologists.

Dr. Drew Carey discusses this shortage of neuro-ophthalmologists and the need for technological and diagnostic aids for greater outpatient access with Dr. Valérie Biousse, author of “Neuro-ophthalmology Emergency Department and Inpatient Consultations at a Large Academic Referral Center.”

Neuro-ophthalmology Emergency Department and Inpatient Consultations at a Large Academic Referral Center. Okrent Smolar, Avital Lily et al. Ophthalmology, Volume 130, Issue 12, 1304 – 1312

Syphilis is often known as the “the great masquerader” because it can mimic symptoms and look like a wide array of other diseases. Dr. Edmund Tsui interviews Dr. Michael Huvard to get to the bottom of how acute syphilitic posterior placoid chorioretinopathy presents itself in eyes and the outcomes for these patients, from his Ophthalmology article “Clinical Characteristics and Visual Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy”

Clinical Characteristics and Visual Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy. Mirzania, Delaram et al. Ophthalmology Retina, Volume 7, Issue 12, 1080 - 1086

Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Dr. Drew Carey sits down with Dr. Thomas V. Johnson to discuss the work of the RReSTORe Consortium in the field of regenerative medicine as applied to optic neuropathies from his Ophthalmology Science article, “The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, & Optic Nerve Regeneration (RReSTORe) Consortium.”

For more of the Ophthalmology Science special issue on Neuroprotection, Neuroenhancement, and Neuroregeneration visit https://www.ophthalmologyscience.org/xops-vsi-neuroprotection

For more information on the RReSTORe Consortium visit: https://www.johnsonlab.co/rrestore-home/rrestore-main-page/

The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration Consortium. Johnson, Thomas V. et al. Ophthalmology Science, Volume 3, Issue 4.

Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Endothelial keratoplasty (EK) procedures have become the preferred method of corneal transplantation in the United States. As the frequency of EKs increase, so do associated costs.

Dr. Matt Feng interviews Drs. David S. Portney and Shahzad I. Mian about their recent analysis

to assess for differences in surgical costs and surgery length based on type of EK, use of preloaded grafts, and performance of simultaneous cataract surgery with EK from their Ophthalmology article “Cost Drivers of Endothelial Keratoplasty: A Time-Driven Activity-Based Costing Analysis.”

Cost Drivers of Endothelial Keratoplasty. Goldstein, Jenna K. et al. Ophthalmology, Volume 130, Issue 10, 1073 – 1079.

Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

The Primary Tube Versus Trabeculectomy Study is a multicenter randomized clinical trial comparing the safety and efficacy of tube shunt surgery and trabeculectomy with mitomycin C in eyes without previous ocular surgery. Dr. Lori Provencher sits down with authors Dr. Sara J. Coulon and Dr. Steven J. Gedde to discuss the results of this trial from their Ophthalmology Glaucoma article, “Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy Study.”

Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy Study. Coulon, Sara J.Gedde, Steven J. et al. Ophthalmology Glaucoma, Volume 6, Issue 4, 422 – 431.

Myelin oligodendrocyte glycoprotein-related optic neuritis is typically associated with good visual outcome in most patients, but poor outcomes are reported in 15% to 36.8% of patients. Dr. Drew Carey sits down with Dr. Edward Margolin to discuss the possible factors associated with poor outcomes, from his Ophthalmology article, “Predictors of Poor Visual Outcome in MOG-related Optic Neuritis.”

Predictors of Poor Visual Outcome in Myelin Oligodendrocyte Glycoprotein-Related Optic Neuritis. Handzic, Armin et al. Ophthalmology, Volume 130, Issue 9, 993 - 995

Recorded live at AAO 2023 and we’re myth busting common ophthalmologic misconceptions of the anterior segment. Drs. Drew Carey and Matt Feng interview Dr. Todd Margolis on his recent Ophthalmology editorial, “Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology.” He shares bonus myths not in the editorial, and takes questions from the audience.

(Producer’s note: Please excuse the audio quality. This episode was recorded on the convention center floor using an iPhone.)

Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Margolis, Todd P. & Galor, Anat. Ophthalmology, Volume 130, Issue 8, 783 – 785.