The most engaging conversation between health professionals happens in chance meetings in the hallways. During these moments so much is learned .*One Thing* brings together thought leaders in conversation and we share it with health enthusiasts , practitioners, and learners. Our conversations primarily focus on one significant thing in the arenas of gut health, brain health, immune system, metabolism, performance, and aging . This for clinicians and patients alike who are insightful and motivated.
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Episode 114: Understanding the Cell Danger Response with Dr. Paul Anderson
Season 6 · Episode 147
Tuesday, March 25, 2025 • Duration 57:21
In this episode of The One Thing Podcast, Dr. Adam Rinde and Dr. Paul Anderson discuss a powerful concept shaping chronic illness care: the Cell Danger Response (CDR).
If you or someone you know is dealing with persistent fatigue, inflammation, long COVID, or autoimmune challenges, this discussion offers deep insights into what may be happening at the cellular level—and why traditional approaches often fall short.
Dr. Anderson explains the phases of the CDR, how it affects mitochondrial function, and why some patients feel worse when they start treatment. They also explore supportive therapies, the importance of gentle intervention, and how to approach healing sustainably and individually.
Key topics:
What is the Cell Danger Response?
How CDR connects to chronic illness, PTSD, and autism
Common treatment pitfalls and how to avoid them
When to support vs. when to detox
The future of mitochondrial medicine and personalized healing
Whether you're a practitioner or navigating your own health journey, this episode provides clarity, compassion, and actionable takeaways.
🎙️ Hosted by Dr. Adam Rinde 🧠 Guest: Dr. Paul Anderson
Episode. 113 – Unlocking Migraine Relief: A Holistic Approach with Dr. Sui Wong
Season 6 · Episode 113
Wednesday, March 12, 2025 • Duration 52:24
In this episode of The One Thing Podcast, host Adam Rinde interviews neurologist Dr. Sui Wong to discuss a revolutionary approach to migraine management. Migraines are often treated reactively, but what if we could build resilience against them from the ground up? Dr. Wong shares insights into how lifestyle interventions, brain resilience, and nervous system regulation can play a crucial role in reducing migraine attacks.
They also dive into: 🧠 The science behind migraines and why they’re more than just headaches 💡 How stress and lifestyle factors influence migraine frequency 🌙 The importance of sleep, nutrition, and physical activity in brain health 🔥 Dr. Wong’s unique "boiling pot" analogy for managing migraine triggers 📚 Her latest books on brain health, mindfulness, and metabolic health
If you or someone you know struggles with migraines, this episode is packed with actionable strategies and cutting-edge research. Don't forget to subscribe and hit the bell for more insightful conversations!
🔗 Links & Resources: 📖 Dr. Sui Wong’s Books: drsuiwongmd.com 📩 Sign up for Dr. Wong’s Thursday Tips Newsletter: 🌐 Visual Snow Initiative: [Link]
Our Affiliate Sponsors:
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⏳ TIMESTAMPS: 00:00 – Introduction & Sponsor Message 01:03 – Why migraines need a new approach03:30 – Dr. Sui Wong’s journey in neurology & lifestyle medicine11:00 – Quality of life and chronic conditions18:00 – What we now understand about migraines25:00 – The role of sleep, nutrition, and physical activity in brain health33:00 – How stress & the autonomic nervous system impact migraines40:00 – Strengthening resilience & preventing migraine attacks46:00 – Dr. Wong’s books and resources50:00 – Supporting Visual Snow Research
Episode 112. Unlocking the Microbiome: Martha Carlin’s Journey into Gut Health & Parkinson’s 💡
Season 6 · Episode 112
Saturday, February 22, 2025 • Duration 46:35
Parkinson's and gut health: The connection you need to understand! Uncover practical steps you can take today to support a healthier gut environment and improve overall well-being for both patient and caregiver
In this episode of The One Thing Podcast, Dr. Adam Rinde dives deep into the fascinating world of the microbiome with Martha Carlin, a citizen scientist, entrepreneur, and microbiome expert. After her husband's Parkinson’s diagnosis, Martha took a radical approach—teaching herself chemistry, microbiology, and systems biology to uncover the connection between gut health and neurological conditions. Martha is the founder of **The Biocollective** and **BiotiQuest** @biotiquest4511 , and her research has led to groundbreaking discoveries in gut health, probiotics, and disease prevention. In this episode, she shares insights on how the microbiome impacts brain health, digestion, and overall well-being, including how gut bacteria might be a key player in Parkinson’s disease. 🔬
**Key Topics Covered:**
✅ Martha’s journey from business consultant to microbiome researcher
✅ The link between **gut health and Parkinson’s** disease ✅ The role of **probiotics, prebiotics, postbiotics, and phages**
✅ How **gut bacteria influence dopamine levels** and brain function
✅ The surprising impact of **oral health and gut permeability**
✅ How a **simple dietary hack** helped her husband sleep better
✅ The latest in **probiotic research & the future of gut health**
📌 **TIMESTAMPS:**
00:00 - Intro to The One Thing Podcast 🎙️
01:30 - Meet **Martha Carlin** & her journey into microbiome research
Episode 111 . Gillian Ehrlich, DNP, ARNP Advanced Medicine For Chronic Disease with ancient origins
Childhood: Grew up in polluted Cleveland, OH, noticing tired adults; standard American diet.
Jane Esselstyn: Health teacher (daughter of Dr. Caldwell Esselstyn) inspired her with her focus on outdoor education and veganism.
Hypermobility: Personal experience with #hypermobility, #EhlersDanlosSyndrome, #POTS, and #mastcellactivation led to finding exercise that worked (rowing).
Exploration: Interested in health, but questioned the traditional medical model; explored outdoor leadership, farming, sailing.
Ayurveda: Introduced to #Ayurveda by a friend, attended classes with Dr. Vasant Lad, then studied at the Ayurvedic Institute (2000-2001).
III. Integrating Ayurveda with Western Medicine (10:38-13:48)
Desire for Change: Aimed to bring #Ayurveda insights into conventional medicine; mentored by Keisha Ewers, Dr. Eileen Ruhoy, and Arti Chandra.
Challenges: Faced limitations in using #Ayurveda in primary care systems (Swedish, Harborview), due to visit length restrictions.
Neuroveda Health: Created own practice to practice freely, offering customized treatments and practical support.
Is Long COVID wreaking havoc on your nervous system? In episode 110 of The One Thing Podcast, Dr. Adam Rinde interviews Dr. Robert Groysman, an anesthesiologist (MD), and pioneer in treating dysautonomia (autonomic nervous system dysfunction) and post-viral illness. Discover groundbreaking therapies, including:
* **Vagal Nerve Stimulation (VNS):** Learn how affordable, transcutaneous VNS can help regulate inflammation and calm your nervous system ,
* **Stellate Ganglion Blocks:** Understand how this procedure, initially used for PTSD, is now offering relief from Long COVID symptoms.,
* **The EAT Procedure:** Discover a novel Japanese therapy (epipharyngeal abrasive therapy) targeting the root causes of inflammation, even stubborn conditions like tinnitus and Eustachian tube dysfunction.
Dr. Groysman shares his unique approach to treating Long COVID, focusing on four primary causes: dysautonomia, mitochondrial dysfunction, gut dysbiosis, and mast cell activation (histamine issues). He also discusses the importance of the vagus nerve in inflammation management and why standard treatments for POTS might not be enough to address the full scope of dysautonomia.
**If you're struggling with Long COVID, chronic fatigue, brain fog, or other post-viral symptoms, this episode is a must-watch!**
0:00 - Intro: Long COVID, Dysautonomia, and the Autonomic Nervous System
1:07 - Introducing Dr. Robert Groysman and His Journey
3:24 - Dr. Groysman's Medical Background and Interest in Long COVID
5:03 - Stellate Ganglion Blocks for PTSD and Connection to Long COVID
7:20 - How Dysautonomia Drives Long COVID Inflammation
9:19 - The Four Primary Causes of Long COVID11:18 - Inflammatory Mediators and Brain Fog
12:25 - Defining Dysautonomia and the Role of the Vagus Nerve
14:28 - The Vagus Nerve and Its Anti-Inflammatory Pathway
16:43 - Vagal Nerve Stimulation as a Treatment for Inflammation
Episode 109. Type 2 Diabetes Reversal with Sami Inkinen
Season 7 · Episode 109
Wednesday, November 13, 2024 • Duration 49:12
In this Episode I welcome on Sami Inkinen CEO of Virta Health to discuss Virta Health's approach to Type 2 Diabetes reversal'
Virta Health utilizes a continuous remote care intervention (CCI) that incorporates individualized carbohydrate restriction, health coaching, and telemedicine to manage and reverse Type 2 Diabetes
We cover topics such as:
Impact of individualized carbohydrate restriction:
Long-Term Effects of CCI: A 2-year non-randomized clinical trial published in Frontiers in Endocrinology showed significant and sustained improvements in multiple clinical markers of diabetes and cardiometabolic health in the CCI group compared to the UC (usual care) group . These included reductions in HbA1c, fasting glucose and insulin, weight, blood pressure, triglycerides, and liver alanine transaminase . The CCI group also saw higher rates of diabetes reversal and remission .
GLP-1 Deprescription: A recent study published in Diabetes Therapy explored the impact of discontinuing GLP-1 agonists in patients who had successfully integrated Carb-Restriction Nutrient Therapy (CRNT) supported by Virta's telemedicine model . The study found that patients did not experience weight regain after stopping GLP-1 medications, and while HbA1c levels increased slightly, they generally remained below the diagnostic threshold for diabetes
About Sami:
Episode 108. Hypercoagulation in Chronic Illness with Dr. Paul Anderson
Season 7 · Episode 108
Tuesday, October 29, 2024 • Duration 01:12:59
In this episode of The One Thing Podcast, hosted by Dr. Adam Rinde, the focus is on integrative and naturopathic medicine, specifically addressing complex chronic illnesses and cancer care. Dr. Rinde introduces the guest, Dr. Paul Anderson, a leading voice in the field with over 30 years of clinical experience. The episode aims to explore the topic of coagulopathy in chronic disease, discussing its mechanisms, implications, and potential treatments.
Guest Highlights
• Dr. Paul Anderson:
o Leading voice in integrative and naturopathic medicine.
o Specializes in complex chronic illness and cancer care.
o Over 30 years of clinical experience.
o Led the interventional arm of a US NIH-funded human research trial on IV and integrative therapies for cancer patients.
o Founder of Advanced Medical Therapies in Seattle, Washington.
o Collaborates with clinics and hospitals worldwide.
o Academic contributions include serving as a professor of pharmacology and clinical medicine and as the chief of IV Services for Baer's Oncology Research Center.
o Published works include "Outside the Box Cancer Therapies" and "Cancer, the Journey for Diagnosis to Empowerment."
o Notable work on intravenous nutrient therapy featured in a scientific reference textbook.
Main Topics Covered
1. Mechanisms of Coagulation:
o Discussion on the intrinsic and extrinsic pathways of coagulation.
o Role of immune chemicals in triggering clotting.
o Impact of chronic illnesses and infections like COVID-19 on coagulation.
2. Coagulopathy in Chronic Disease:
o Excessive coagulation in chronic disease states.
o Specific conditions discussed include COVID-19, fibromyalgia, chronic fatigue syndrome, and POTS (postural orthostatic tachycardia syndrome).
o How coagulopathies may hinder patient recovery and the importance of assessing and addressing these issues.
3. Genetic and Environmental Factors:
o Influence of genetics on susceptibility to hypercoagulability.
o Role of diet, hydration, and lifestyle in managing coagulation issues.
o Importance of testing and early detection for prevention and treatment.
4. Treatment Approaches:
o Use of supplements like vitamin E, omega oils, and fibrinolytic enzymes (e.g., nattokinase, lumbrokinase).
o Potential use of baby aspirin for managing clotting issues.
o Importance of a stepwise approach to treatment, starting with lifestyle modifications and progressing to more intensive interventions if necessary.
5. Biofilm and Chronic Infections:
o Connection between biofilm formation and chronic infections.
o How pathogens use fibrin to form protective biofilms, complicating treatment.
o Strategies for breaking down biofilms to improve patient outcomes.
6. Hope and Recovery:
o Emphasis on the possibility of recovery from chronic illnesses and coagulopathies.
o Importance of finding a supportive healthcare team and utilizing available resources for treatment and management
• Social Media Handles:
o Twitter: @DrAConsult
o LinkedIn: Dr. Paul Anderson
• Website: ConsultDrAnderson.com
Episode 107 .Arsenic and Your Health: Expert Advice from Dr. Joe Pizzorno"
Season 6 · Episode 107
Friday, September 20, 2024 • Duration 01:01:47
The Toxins We Ignore: Insights from Dr. Pizzorno on Naturopathic Medicine, Detoxification, and Environmental Contaminants .In this episode of the One Thing Podcast, we have the honor of speaking with Dr. Joseph Pizzorno, a pioneering naturopathic physician, educator, researcher, and author. Dr. Pizzorno' s profound influence on the field of naturopathic and functional medicine is well-recognized as he delves into his journey from founding Bastyr University to his current ventures. The conversation covers his initial inspiration, essential life lessons, and invaluable insights into the impact of environmental contaminants on health. Dr. Pizzorno sheds light on the significance of detoxification and the role of natural medicine in promoting overall well-being. He also discusses the importance of clean nutrition, the unseen hazards of arsenic, and practical steps to reduce toxic exposures. Whether you are a healthcare professional or someone invested in your health, this episode is packed with actionable insights and valuable knowledge.#detoxification #naturopathicmedicine , #DrPizzorno, #FunctionalMedicine, #ArsenicToxicity, #EnvironmentalHealth, #HealthTips, #CleanEating, #ToxinFree
Topics discussed:
Introduction and Personal Connection
Current Ventures and Focus on Health
Environmental Medicine and Chronic Diseases
Corporate Wellness and Nutritional Deficiencies
Functional Medicine and Foundational Concepts
Deep Dive into Arsenic Toxicity
Filtering Contaminated Water
Testing and Labs for Water Safety
Avoidance and Detox Strategies
The Toxin Solution Program
Persistent vs. Non-Persistent Toxins
Detoxifying the Body
Kidney Health and Detoxification
The Role of Glutathione
Advice for Different Life Stages
The Importance of Real Food
Final Thoughts and Reflection
About Dr. Pizzorno:
Dr. Joseph Pizzorno, ND is a transformational leader in medicine. Through half a century of work, he
has helped establish and advance the academic, scientific, and clinical foundation of natural, functional, integrative, and environmental medicine. As founding president of Bastyr University in 1978, he coined the term “science-based natural medicine” and led Bastyr to become the first ever accredited institution in the field. He has set worldwide standards of practice by authoring or co-authoring 6 textbooks for doctors, including the Textbook of Natural Medicine (over 100,000 copies in 4 languages across 5 editions) and Clinical Environmental Medicine. He is Editor-in-Chief of PubMed-indexed IMCJ—the most widely read, peer-reviewed journal in the field (25,000 copies each issue). He is a founding member of the Board of Directors of the Institute for Functional Medicine, where he served 3 terms as Chair. A licensed naturopathic physician, educator, researcher, and expert spokesman, he is also author or co-author of 8 consumer books (most recent, Healthy Bones, Healthy You! with wife Lara).
show notes at
Episode 106. Dr. Orli Peter Trauma response and PTSD in the Middle East
Season 6 · Episode 106
Tuesday, September 3, 2024 • Duration 01:07:36
In this episode of the One Thing podcast, Dr. Peter
discusses the profound impact of her father's experiences as a Holocaust survivor on her life and career as a trauma psychologist.
The conversation delves into the effects of generational trauma, the physiological and psychological responses to significant traumatic events, and the steps taken to aid survivors of the recent October 7th attacks in Israel. Dr. Peter highlights her work with the Israel Healing Initiative, emphasizing the importance of neurostimulation in trauma treatment and her ongoing efforts to provide support across affected communities, including Jewish, Palestinian, Bedouin, and Druze populations. The discussion includes poignant survivor stories and touches upon the broader implications of trauma within a global context. The conversation highlights, stories of heroism during October 7, the importance of social support, the difference between real trauma and perceived trauma, and the need for practical solutions to promote post-traumatic growth. The episode provides invaluable knowledge on trauma response, the use of vagal nerve stimulation, neurostimulation, and ways to support continued efforts in mitigating trauma's impact on both Israeli and Palestinian communities.
Here are some of the topics we cover:
Father's Journey and Influence
9/11 and Global Reactions
Understanding Trauma and PTSD
October 7th Events and Initial Reactions
Personal Stories of Survival
Neurostimulation and Trauma Treatment
Scaling Up Nonprofit Efforts
Treating Trauma with Vagus Nerve Stimulators
Personal Stories of Trauma and Healing
Understanding the Physical Impact of Trauma
The Role of Neurostimulation in Post-Traumatic
Growth
Supporting the Israel Healing Initiative
About Dr. Peter:
As the daughter of a Holocaust survivor, Dr. Peter has devoted her three-decade career to providing specialized treatment to survivors worldwide. Her experience spans diverse communities, including Iranian refugees, residents of the Qalandia refugee camp, and individuals from Arab, Druze, and Jewish Israeli backgrounds in the aftermath of the war. She has also provided support to witnesses of the 9/11 attacks.
Episode 105 : The Beauty and Burden of Autism with Dr. Sandra Paulsen
Season 6 · Episode 105
Wednesday, August 21, 2024 • Duration 01:03:30
In episode 105 of the One Thing Podcast, Dr. Adam Rinde
interviews Dr. Sandra Paulsen, a renowned psychologist and author, about her professional journey and expertise in psychotherapy, focusing on her work with autism and Eye Movement Desensitization and Reprocessing (EMDR). Dr. Paulsen discusses her own experiences with autism, her approach to treating trauma in autistic patients, and the need for gentle, tailored interventions due to their
sensitive nervous systems. She also touches on the complexities and gifts of autism, the importance of recognizing emotional and physical sensations in
therapy, and her use of visual aids and cartoons. Throughout the episode, Dr.Paulsen addresses controversial topics in the autism field, talks about her
newest book, 'The Beauty and Burden of Autism,' and shares insights on the unterconnectedness of autism with other conditions like anxiety, PTSD, and OCD.
Dr. Rinde and Dr. Paulsen reflect on the challenges and future prospects for those on the autism spectrum, emphasizing the importance of support and
tailored therapeutic approaches.
In the event the podcast exceeds 300 views (YouTube and
Podcasts plays) in the first 30 days The One Thing Podcast will donate at least
$100 @emdrhap Humanitarian Assistance Program https://www.emdrhap.org/
Time stamps:
00:00 Introduction to the Podcast and Guest
04:31 Dr. Sandra Paulson's Professional Journey
07:36 Discovering and Embracing Autism
09:42 The Beauty and Burden of Autism
17:27 Controversies and Misconceptions in Autism
31:35 Exploring Autism in Women
32:09 Challenges in Relationships
34:20 Masking and Camouflage
37:44 Spoon Theory and Terminology
39:36 Overlap of Conditions
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IV. Patient Experiences and Philosophy (13:48-18:11)
Individuality: Believes people thrive when being themselves, not "average;" Sees beauty in human diversity.
Teacher Role: Sees herself as a teacher, helping patients understand needs; emphasizes relaxation for healing (using humor for comfort).
Patient Focus: Patients should leave feeling empowered and with the tools to improve their health.
V. Neuroveda Health & Integrative Approach (18:11-32:04)
Spectrum of Health: Sees complex disease and #longevity as a spectrum of #oxidativeStress, sharing similar approaches.
Pancha Karma: Introduced #PanchaKarma (Ayurvedic detoxification), with key components: oilation, treatments, and elimination.
Executive Longevity Program (ELP): Modeled on #PanchaKarma, offers 3-21 day programs. Includes #Ayurvedic bodywork, #plasmapheresis, #IVIG, #stemcells, #prolotherapy, ozone, #NAD, mitochondrial #IVs, #ketamine therapy. Designed for significant shifts and then a return to primary providers.
Diagnostics/Therapies: Offers autonomic testing, EDS evaluation, skin biopsies, craniocervical instability testing, and other advanced therapies.
Frustrations: Noted that patients find #Ayurveda after exhausting all other options. Emphasized the need for neuroplasticity.
VI. Ayurvedic Principles in Practice (32:04-37:53)
Core Philosophy: #Ayurvedic medicine is core, integrating therapies within this framework.
Plasmapheresis/Raktamokshana: Links #plasmapheresis to #Ayurvedic practice of "Raktamokshana" (blood removal) part of #PanchaKarma.
Personalization: Treatment is based on disease patterns and #doshas.
Case Example: CRPS patient case of using gentle massage because of high #Vata; Digestion was a consideration in her case.
Unique Approach: #Neuroveda has a unifying philosophy rooted in #Ayurveda, while other clinics may just combine modalities.
Sami Inkinen is the Chief Executive Officer and Co-Founder of Virta Health, the leader in diabetes reversal and sustainable weight loss. With a combination of proven nutrition, expert support, and advanced technology, Virta empowers members with the tools and knowledge to sustain changes for a longer, healthier life.
A data-driven technology entrepreneur, Sami's personal experience with diabetes and passion to advance global health was the motivation behind Virta. Working with over 500 large employers, health plans, and government organizations across the country, Virta has helped over 100,000 members reverse their diabetes and obesity.
Previously, Sami was co-founder of leading online real estate marketplace Trulia, serving as its COO, president, and board member until its IPO and eventual sale to Zillow Group, and held roles at Microsoft and McKinsey & Company. He also founded Fat Chance Row to raise awareness of the dangers of sugar and its connection to diabetes, rowing from California to Hawaii — 2,750 miles — with his wife, completely unsupported.
He holds a MS in engineering physics from the Helsinki University of Technology and a MBA from Stanford University, and is also a triathlon age group world champion and 8 hour 24 minute Ironman finisher, having completed seven Hawaii Ironmans. He lives in Colorado with his wife and two daughters, enjoying the outdoors and the delight of their small barn of egg-laying chickens.
Related Links
1. Dr. Paul Anderson's Books:
o "Outside the Box Cancer Therapies" by Dr. Paul Anderson and Dr. Mark Stengler
o "Cancer, the Journey from Diagnosis to Empowerment" by Dr. Paul Anderson
2. Research on Coagulation and COVID-19:
o Studies on interleukin-6 and its role in COVID-19
o Research on microclots in COVID-19 patients
3. Supplements Mentioned:
o Nattokinase
o Lumbrokinase
o Baby aspirin
o Vitamin E
o Omega oils
4. Organizations and Labs:
o Fry Laboratories (historical reference)
5. Conditions Discussed:
o COVID-19 and Long COVID
Previously holding the role of associate professor of psychology at Mount St. Mary’s University in Los Angeles, Dr. Peter oversaw the Psychology Graduate Programs and served as acting Chair of the Psychology Department.
Dr. Peter’s academic journey culminated in a Ph.D. from the University of California at Berkeley, followed by three postdoctoral fellowships in clinical psychology, social psychology, and neuropsychology. Her dedication led to diplomate status in Clinical Psychology from the American Board of Psychological Specialties. Her expertise is deepened by her studies with pioneers in the field of Interpersonal Neurobiology, such as UCLA professors Allan Schore and Dan Siegel. This expertise allows her to effectively apply these principles in helping traumatized individuals regulate their emotions.
Her certification in Homeland Security by the American Board of Psychological Specialties speaks to her expertise in trauma-related research and treatment. Her consultancy with the RAND Corporation on terrorism research demonstrates her commitment to understanding and addressing the psychological impact of traumatic events.
Dr. Peter is the Vice President of Free Hearts Free Minds, an organization that provides trauma counseling and support to free-thinking ex-Muslims who have faced or are at risk of persecution from their families or communities.
Sandra Paulsen, Ph.D., is an international instructor, author and illustrator of principles and procedures for using EMDR with complex trauma including structural and somatic dissociation and trauma held in implicit memory. Her books include coediting The Neurobiology and Treatment of Traumatic Dissociation: Toward an Embodied Self. She wrote and illustrated Looking Through the Eyes of Trauma: An Illustrated Guide for EMDR Therapists and Clients; and When There Are No Words: EMDR for Very Early Trauma in Implicit Memory, and coauthored We’re Listening Body: Integrating EMDR, Somatic and Ego State Therapies.
2024 publications will include: The Beauty and Burden of Autism: An Illustrated Guide and Workbook, and Indigenous Trauma and Dissociation: Healers, Psychotherapies and the Drum, with Shelley Spear Chief. She also coauthored and illustrated a children's book that is also useful for dissociative adults called All the Colors of Me: My First Book on Dissociation. Sandra is a Fellow of the International Society for the Study of Trauma and Dissociation.
