Axiom Catalyst – Details, episodes & analysis

Over the past few decades, bladder cancer standard of care has not changed, with platinum-based chemotherapy and BCG as the core pillars of care. The last 12 months have seen two new regimens approved for frontline locally advanced / metastatic urothelial and one new treatment approved for BCG-unresponsive CIS NMIBC, significantly improving survival outcomes for patients. Many other clinical programs have continued progressing, ushering in a new wave of novel, targeted, and potentially more tolerable bladder cancer treatments. 

In this Bladder Cancer Awareness Month special episode of Axiom Catalyst, Andrew Kassin and Kiana Ziadkhanpour interview Dr. Petros Grivas, a thought-leading GU Medical Oncologist of University of Washington and Fred Hutchinson Cancer Center, to discuss innovative bladder cancer treatments, changing treatment practices, and patient risk factors. 

We are honored to continue spreading awareness for bladder cancer to help patients around the world! #BladderCancerAwarenessMonth2024 #AxiomThinkTank

Severe care disparities, barriers to diagnosis, harrowing patient stories, historically low survival… and yet… enduring hope for women worldwide.
While significant progress has been made to address needs of women with gynecologic cancers, and the last 12 month have seen huge strides in advancing standards of care, key challenges remain including the inclusivity of clinical studies, asymmetric engagement and awareness across communities, and limited ability to tailor therapies, especially in later lines as care options dry up.
In this this Gynecologic Cancer Awareness Month special episode of Axiom Catalyst, Dan Simpson, Carlie Darefsky, Harish Venkatesan and Flannery Nania talk through the challenges and hope for patients, as we look to the healthcare industry to raise the bar on health standards.
This short podcast complements the specific infographics the Axiom team developed to highlight specific needs and challenges in cervical, ovarian and endometrial cancers respectively.

Let’s keep raising awareness and saving lives! 🌸💪

#CervicalCancer #OverianCancer #EndometrialCancer #HealthcareAdvocacy #TogetherAgainstCancer #GynecologicCancer #GynAwarenessMonth2023 #AxiomThinkTank 

In collaboration with Nick Gherardin from University of Melbourne, and Hafiz, Anne has recently co-authored a review article in Frontiers in Oncology about the novel clinical strategies companies are taking to bring gamma delta-inspired therapies to the clinic.

Anne Cherry joins the Axiom Catalyst with Mahim Misra to discuss her paper and some of the exciting developments in gamma delta inspired therapies.

Dr. John Tsai, former President of Global Drug Development and CMO of Novartis, joins the Axiom Table with Hafiz Sikder. The conversation spans the changing landscape of Immuno-Oncology, AI, and the impact of COVID-19.

Michelle Werner, CEO Partner of Flagship Pioneering and CEO of Alltrna, joins Hafiz Sikder to discuss her work and role at Alltrna as well as her personal investment in the field. She dives deep into the impact of tRNA on drug development, premature stop codons, and her drive to do more for rare disease.

Join us as we discuss the latest developments in RCC coming out of ESMO22. In this episode, we recap the impact of 3 failed checkpoint-based regimen trials within the (neo)adjuvant setting and the first positive triplet data for advanced RCC.

Join us as Rohan and Andrew discuss key takeaways from an impactful ESMO22 in NSCLC. In this episode, we recap the first Phase III data for a KRASG12C inhibitor, long-term follow-up from checkpoint-based regimens, and the first ADC approval in lung.

Dr. Hope Rugo, University of California at San Francisco, joins Hafiz Sikder for an engaging discussion on the world of Breast Cancer. The discussion ranges from key ESMO data, the future of care, and healthcare disparities.

Join in this week as we review key data-set from ESMO as well as a deep dive into RCC, lung and pan-tumor discussions. Join in the discussion with your POV, comments, and questions.

Axiom Catalyst is live from Gustave Roussy! Hafiz Sikder joins Dr. Barlesi and the leading cancer treatment team in Villejuif, France for a discussion on the future of oncology.