What is the difference between peptides and bioregulators, and could bioregulators represent the next evolution of peptide therapy?
In Episode 23, Max Plasencia and Mike Sheffer dive deep into bioregulators, peptide signaling, gene expression, recovery, cognitive health, muscle growth, mitochondrial function, and the future of health optimization.
The conversation begins with the fundamental differences between traditional peptides and shorter bioregulators. Mike and Max discuss their view that longer-chain peptides primarily act as signaling molecules, while shorter bioregulators may interact more directly at the cellular and gene-expression level.
They explore examples including Ovagen, Testagen, Bronchogen, Livagen, Cardilax, Cortagen and Vessagen, as well as the research associated with Dr. Cavinson and the Cavinson Institute. The discussion also explores potential applications involving aging, tissue health and eyesight.
Mike shares his personal experience with declining eyesight and previous laser eye procedures, leading into a discussion about potential bioregulator combinations for eye health.
The conversation then moves into Cortagen + ARA-290, the relationship between bioregulators and signaling peptides, and why Mike and Max believe a bioregulator could potentially become the foundation of a broader peptide protocol.
Mike and Max also discuss Semax vs. Adamax, PE-22-28, Selank, chronic stress, cortisol, inflammation and mitochondrial health, including Mike's personal experience experimenting with different compounds.
Finally, they introduce FLGR-242, a newer myostatin-inhibition approach designed around muscle growth, albumin binding and longer-lasting activity, and discuss its potential implications for bodybuilding and muscle development.
In This Episode:
- Peptides vs. bioregulators
- What are bioregulators?
- Gene expression and cellular signaling
- Short-chain vs. long-chain peptides
- Cavinson Institute research
- Ovagen, Testagen & Bronchogen
- Livagen & Cardilax
- Bioregulators and aging
- Eye health and eyesight
- Cortagen and Vessagen
- Cortagen + ARA-290
- C-Max vs. Atomax
- PE-2228 and BDNF
- Selank and stress
- Chronic stress and cortisol
- Inflammation and recovery
- SS-31 and mitochondrial health
- NAD and cellular energy
- FLGR-242
- Myostatin inhibition
- Muscle growth and bodybuilding
- The future of peptide technology
About Weekly Pep-Talk: Weekly Pep-Talk is a podcast covering peptides, longevity, GLP-1s, fat loss, bodybuilding, performance enhancement, recovery, biohacking, and health optimization.
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