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Explore every episode of the podcast Upside

Dive into the complete episode list for Upside. Each episode is cataloged with detailed descriptions, making it easy to find and explore specific topics. Keep track of all episodes from your favorite podcast and never miss a moment of insightful content.

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TitlePub. DateDuration
The Seed - Episode 808 Sep 202400:32:06

In this conversation, Dan and Mads discuss various topics including the SuperSaaS event, the Council of Europe's convention on AI, the central bank digital currency, founder mode, and immigration and the future of AI. They highlight key takeaways such as the importance of relationships in dealing with big corporates, the progress made in living standards over the years, the implications of the AI regulation treaty, the characteristics of successful CEOs in founder mode, and the impact of immigration on economic growth and productivity.

Takeaways

  • Building relationships is crucial when dealing with big corporates.
  • There has been significant progress in living standards over the years.
  • The AI regulation treaty has implications for human rights and democratic values.
  • Successful CEOs in founder mode focus on the most important tasks, embrace bad news, and are mission-driven.
  • Immigration plays a vital role in economic growth and productivity.
  • Productivity-enhancing technology investment will be crucial in the coming decade.

Sound Bites

  • "Dealing with big enterprise is always the machine, but actually these guys and girls really value relationships and building relationships."
  • "We made incredible progress in living standards, especially since the 50s."
  • "The US, EU, and UK have signed the Council of Europe's Convention on AI."

Chapters

00:00 SuperSaaS and Building Relationships with Big Corporates

04:08 The Progress in Living Standards

08:20 Implications of the AI Regulation Treaty

22:21 Characteristics of Successful CEOs in Founder Mode

30:51 The Role of Immigration in Economic Growth

33:18 The Importance of Productivity-Enhancing Technology

Keywords

SuperSaaS, Council of Europe, AI regulation, central bank digital currency, founder mode, immigration, future of AI, relationships, living standards, progress, CEO characteristics, economic growth, productivity

The Seed - Episode 701 Sep 202400:28:59

Dan and Mads discuss various topics including the arrest of Pavel Durov, the founder of Telegram, the debate between big and small venture capital firms, the potential impact of the autumn budget on startups, advancements in cancer treatment, the regulation of AI in Europe, Germany's energy transition, and the concept of agentic workflows in business.

keywords
Pavel Durov, Telegram, arrest, children's security, venture capital, big firms, small firms, autumn budget, startups, SEIS, EIS, cancer treatment, AI, agentic workflows, EU regulation, Germany, energy transition

takeaways

  • The arrest of Pavel Durov, the founder of Telegram, raises questions about the responsibility of technology platforms in ensuring security and preventing illegal activities.
  • There is a debate between big and small venture capital firms, with some arguing for more $100 million funds to support a wider range of startups, while others advocate for mega funds to tackle big challenges that require significant capital.
  • The impact of the autumn budget on startups, particularly in relation to SEIS and EIS, is a concern, and there is speculation about potential changes to wealth tax and capital gains tax.
  • Advancements in AI and mRNA technology are driving progress in cancer treatment, with the potential for personalized medicines and significant improvements in survival rates.
  • The regulation of AI in Europe, particularly in relation to agentic workflows, raises questions about the balance between regulation and innovation, and the need for businesses to adapt to changing regulatory environments.
  • Germany's energy transition is a mix of progress in renewables and challenges in phasing out nuclear energy, raising concerns about the country's seriousness in addressing climate change.
  • Agentic workflows, where AI agents within organizations interact and automate functions, are expected to play a significant role in enterprise operations by 2025, enabling more efficient and intelligent workflows.

titles

  • The Rise of Agentic Workflows in Business
  • The Potential Impact of the Autumn Budget on Startups

Sound Bites

  • "Does technology or these kinds of platforms, where does the responsibility start and stop?"
  • "The reason that that's the charge has been put forth is it's just so abhorrent that we can't possibly condone such saw there was speculation that he had been invited"

Chapters

00:00 Introduction and Technical Difficulties

00:11 The Arrest of Pavel Durov and the Responsibility of Technology Platforms

05:01 The Debate Between Bigger and Smaller VC Firms

09:04 The UK Budget and Its Impact on Startups

15:31 The Development of Cancer Vaccines and Personalized Medicine

19:34 The Regulation of AI in Europe and the Potential for Innovation

22:30 Germany's Economy: Stagnation and Renewable Energy

26:15 Agentic Workflows: Revolutionising Business Processes

The Seed - Episode 623 Aug 202400:35:38

Summary
In this conversation, Mads, Dan and Alex discuss various topics including sports team ownership, freedom of movement, startup work culture, AI regulation, and the state of venture capital. They touch on the investment in Venezia FC, the rejection of the freedom of movement proposal by the UK government, the potential risks and benefits of AI, and the recent increase in startup shutdowns. They also explore the impact of politics on the tech industry and the cyclical nature of venture capital.

Keywords
sports team ownership, freedom of movement, startup work culture, AI regulation, venture capital

Takeaways

  • Investing in sports teams can be an exciting opportunity if the business plan and team involved make sense.
  • The rejection of the freedom of movement proposal by the UK government is seen as a short-term outlook that may limit talent and investment opportunities.
  • AI is viewed as both a potential risk and a transformative technology, with companies increasingly recognizing its impact on their business.
  • The debate around AI regulation centers on the balance between innovation and potential risks, with some advocating for awareness-level regulation.
  • The increase in startup shutdowns should be viewed in the context of a higher number of companies being started, indicating a healthy level of entrepreneurial activity.
  • Venture capital returns have been affected by the cyclical nature of the industry, but patient investors who understand the long-term nature of the business can still succeed.

Sound Bites

  • "An investment opportunity sent by Drake's manager"
  • "Freedom of movement for young people is a sensible thing"
  • "US companies seeing AI as a potential risk"

Chapters

00:00 Introduction and Investing Climate 

03:04 Startup Work Culture

06:21 The Potential Risks and Benefits of Artificial Intelligence

16:13 Does Politics Interfere Too Much with Tech?

26:46 The State of the Venture Capital Industry

28:44 The Increase in Startup Shutdowns and the Cyclical Nature of Venture Capital

The Seed - Episode 509 Aug 202400:29:59

Summary
In this conversation, Dan, Mads, and Andreas discuss various topics including the current state of the US economy, raising capital internationally, the role of European VCs in tech policy and politics, and the decision for founders to bootstrap or seek venture capital. They highlight the importance of understanding the global economy and its impact on venture capital, the need for more fund of funds and platforms to make venture accessible, and the potential for VCs to be more involved in policy and regulation. They also emphasise that the decision to go VC or bootstrap depends on the level of ambition and the goal of building a lifestyle business or a global category leader.

Keywords
US economy, raising capital, international, European VCs, tech policy, politics, founders, bootstrap, venture capital

Takeaways

  • The US economy and its consumer spending have a significant impact on the global economy, making it important for venture capitalists to pay attention to market trends.
  • Raising capital internationally can be challenging, with different regions having different preferences and gravitations towards certain investment opportunities.
  • There is a need for more fund of funds and platforms to make venture capital more accessible to non-sophisticated LPs and provide diversification.
  • European VCs should be more involved in tech policy and politics, as they are at the forefront of shaping the future and can contribute valuable insights.
  • The decision for founders to bootstrap or seek venture capital depends on their level of ambition and the goal of building a lifestyle business or a global category leader.

Titles

  • The Role of European VCs in Tech Policy and Politics
  • The Decision for Founders: Bootstrap or Seek Venture Capital

Sound Bites

  • "US consumers will spend less, it'll impact everybody."
  • "Markets may not affect us that much in venture, but a US recession would affect the global economy at large."
  • "Middle East more difficult to penetrate, Asia has a lot of new money, Europe offers better valuations and investment opportunities."

Chapters

00:00 Introduction and Setting the Stage

01:27 Navigating Market Volatility and Economic Indicators

06:19 Considerations for Raising Capital Internationally

19:39 VC Involvement in Tech Policy and Politics

28:20 Choosing Between Bootstrapping and Venture Capital

The Seed - Episode 404 Aug 202400:21:13

Summary
Leo Ringer, co-founder and partner at Form Ventures, discusses the misconception that Europe is a backwater for innovation and startups. He argues that Europe has made significant progress in producing great companies and that the narrative needs to shift to focus on the advantages and strengths of the European ecosystem. Leo suggests creating a streamlined, pan-European legal entity for startups and emphasizes the importance of the tech and investment community coming up with ideas to address regulatory challenges. The conversation also touches on topics such as cryptocurrency, universal basic income, and US consumer fatigue.

Keywords
Europe, innovation, startups, regulation, narrative, pan-European legal entity, cryptocurrency, universal basic income, US consumer fatigue

Takeaways

  • Europe has made significant progress in producing great companies and the narrative needs to shift to focus on the advantages and strengths of the European ecosystem.
  • Creating a streamlined, pan-European legal entity for startups could help address regulatory challenges and promote cross-border collaboration.
  • The tech and investment community should actively contribute ideas to policymakers to shape regulations and overcome regulatory obstacles.
  • Cryptocurrency and its regulation continue to be a polarizing topic, with different perspectives on its future and impact.
  • The rise of artificial intelligence and automation raises questions about the future of work and the need for alternative sources of government revenue, such as sovereign wealth funds.
  • US consumer fatigue and concerns about the US economy's slowdown have global implications and can impact market sentiment and economic outlook.

Titles

  • Cryptocurrency: A Polarizing Topic with Uncertain Future
  • Global Implications: US Consumer Fatigue and Economic Outlook

Sound Bites

  • "We've had 10 years of deciding and telling ourselves that Europe is this sort of backwater. We're not Silicon Valley. All we do is regulate."
  • "We need to lean into that and flip the narrative to say, where does that give us an advantage? Where does it give us an edge?"
  • "A much more streamlined, pan-European kind of legal entity... that investors understand, that founders understand, that capital markets understand and can treat similarly across Europe."

Chapters

00:00 Europe's Innovation Potential

03:45 Addressing Regulatory Challenges

09:43 The Future of Cryptocurrency

13:21 Universal Basic Income

14:47 Funding Public Services in the AI Era

16:53 US Consumer Fatigue and its Global Impact

The Seed - Episode 328 Jul 202400:21:43

Summary

In this episode of The Seed, Dan, Mads, and Maja discuss various topics related to European venture and the startup ecosystem. They cover SPACs, investing vs gambling, the UK and US public markets, go-to-market strategies for AI-first products, and Revolut's UK banking license. The conversation touches on the challenges and opportunities faced by European founders, the importance of creating global champions, and the need for a more unified European ecosystem.

Keywords

European venture, startup ecosystem, SPACs, investing, gambling, UK public markets, US public markets, go-to-market strategies, AI-first products, Revolut, UK banking license, European founders, global champions, unified ecosystem

Takeaways

SPACs are making a comeback as a way for struggling companies with high valuations to go public.
Investing is different from gambling because it involves having an edge and expecting to make a profit over multiple investments.
The UK public markets are showing positive signs, with more institutional capital flowing back into UK equities.
European founders often face challenges in accessing capital and building their businesses, leading them to seek opportunities outside their home countries.
Go-to-market strategies for AI-first products require a focus on value proposition, defining use cases, and developing marketing and sales channels.
Revolut's UK banking license is a significant step towards creating a global champion in the fintech space.
The European ecosystem would benefit from more unity and collaboration to support the growth of startups and create more successful companies.

Chapters

00:00 The Return of SPACs
03:03 Investing vs. Gambling
08:16 The Rebound of the UK Equities Market
12:16 Navigating Fragmented Capital Access
15:30 Go-to-Market Strategies for AI-First Products
18:10 Revolut's UK Banking License

The Seed - Episode 221 Jul 202400:25:15

In this episode, Dan, Mads, and guest Guillermo discuss various topics including the AI bubble, the impact of AI on the sales function, the best route for tech founders, the startup ecosystem in Spain, and the potential effects of a Trump administration on European venture. They also touch on the need for an AI bill in the UK, the challenges of fundraising and going global for startups, and the importance of space exploration.

Chapters

00:00 Introduction
03:40 Transforming the Sales Function with AI
07:42 The Best Route for Tech Founders in Funding
12:53 Challenges and Opportunities in Different Markets
15:14 The Impact of a Trump Administration on European Venture
19:42 The Regulatory Landscape for AI in Spain and the UK
23:57 The Benefits of Space Exploration

Takeaways

There is a debate about whether AI is in a bubble, with some arguing that the amount of capital going into AI may not result in enough future revenue to counteract the expenses.
AI has the potential to transform the sales function by enabling sales reps to do more and automate certain tasks, but there are concerns about the impact of AI on job roles and the genericisation of content.
Raising venture capital is not suitable for every tech founder, and bootstrapping may be a better option for some. It depends on the founder's goals, the potential for global growth, and the need for rapid scaling.
The startup ecosystem in Spain is smaller compared to countries like the UK and Germany, which can limit growth opportunities for local startups. Going global and targeting international markets early on can increase the chances of success.
The UK government is considering an AI bill, but there are concerns about the potential impact on AI research and development. The UK's permissive regime has been beneficial for innovation, and it remains to be seen how regulations will evolve post-Brexit.
Space exploration, such as returning to the moon, can lead to scientific advancements and technological innovations that benefit society as a whole.


The Seed - Episode 114 Jul 202400:33:50

Every week we all discuss what's been bothering us in startup land. Howard Kingston joins Mads and I this week, and we dig into:

  • Govt endorsement - death knell or life force?
  • New stock exchange rules - will they make any difference?
  • Why don't we want to see European founders rich?
  • Founder financial wellbeing - is it the VCs responsibility?
  • AI - how will it make or break my startup?
  • Comms, marketing and branding hacks

And more...


The Seed - Pilot07 Jul 202400:30:40

My partner Mads and I share the same vision and values but see the world completely differently. We fight, we love, we share, we build, we do, we ponder, we tussle... rinse repeat. Often having difficult conversations behind the scenes that we've decided to have in public. 

This week we're talking about:

  • The new govt. and what it means for our industry.
  • Can we rebuild our relationship with the EU, should we.
  • Is NVIDIA worth $3trn - would you buy now.
  • Can AI impact education and how.
  • AI in VC - yes no good bad how when.
  • What is our responsibility as VCs to the future for our children. 
  • What makes a great founder.
The Seed #14 - hAIpe at Perplexity, Claude controlling the desktop, Palantir & the NHS, is everyone a media company? US markets will chill27 Oct 202400:25:36

In this conversation Dan and Mads explore crazy hAIpe valuations at Perplexity, Claude controlling the desktop in Enterprise - but RPA is nothing new, Palantir, the NHS and patient records? Is everyone becoming a media company? American markets will chill the growth now, what will a Trump administration really mean for the economy? And more...

Chapters
00:00 AI Valuations are Going to be hAIpe. Right?
01:58 AI in RPA in the Enterprise - I won't close the podbay doors Dave.
03:45 NHS Digital Records, Palentir, any Opportunities for Startups?
07:24 NHS Technology (failed) Implementations
10:09 The Future of Workforce and AI Integration
12:59 The Content Economy - is Everyone Becoming a Media Business?
15:47 Europe's Innovation Gap Again - Will Draghi win out?
18:38 AI's is the Only Way to Grow (Within the Resources we Have)
21:43 What Will a Trump Admin Really Mean for the Economy?
24:28 The Future is a Gift

The Seed #13 - who cares about climate, Trump poll trolls, liquidity is nowhere, UK trade, and is the EU project over?20 Oct 202400:37:54

In this conversation, Dan and Mads explore the current state of European venture capital, who cares about climate change? insights from the UK International Investment Summit, public sector investment could cost us nothing, and make us everything, Trumps trolls in the polls, EU Inc Petition - any teeth? SpaceX caught a thing - so what, liquidity is everything in VC. 

Takeaways
• UK based VCs are on track to raise over £12bn this year - more than 2021.
• Corporates bow out of COP29 - virtue signalling over?
• Investment in climate tech is projected to drop by 20% in 2024.
• The UK International Investment Summit - meaningful outcomes?
• Public sector investment can potentially cost nothing & create everything.
• The EU project - is it over?
• The EU Inc petition - any teeth?
• SpaceX's caught a thing, so what?
• Venture capital is experiencing a lack of exits = no liquidity - now what?
• Trump and trolls in the polls
• The answer to strategic investment that will really drive growth.

Chapters
00:00 European Venture Capital Landscape
07:03 Climate Change and Corporate Responsibility
12:01 UK International Investment Summit Insights
17:04 Public Sector Investment and Economic Growth
24:39 The Future of the European Project - Is the EU dead?
28:59 EU Inc Petition - any teeth?
31:12 SpaceX caught at thing - so what?
37:31 Venture Capital and liquidity - where is it coming from?

Keywords
European venture capital, climate change, UK investment, public sector investment, EU project, startup ecosystem, SpaceX, venture capital challenges

The Seed #12 - UK Budget, Are LPs Still Grumpy, DOJ Breaking up Google, Where Are All The Startups13 Oct 202400:38:58

In this conversation, the hosts discuss a range of topics including the recent Nobel Prizes awarded for AI innovations, the regulatory challenges facing Google, the economic situation in the UK, and the future of venture capital. They explore the implications of the Regulatory Innovation Office in the UK, the appetite of Limited Partners (LPs) for investing in venture capital, and the significance of ownership and location for European startups. The discussion highlights both the challenges and opportunities within the current landscape, emphasising the need for careful handling of emerging technologies and regulatory frameworks.

Takeaways
• Nobel Prizes awarded for AI innovations highlight the importance of technology in medicine and environmental issues.
• AI technologies are fundamental to the current industrial revolution but require careful regulation.
• The DOJ's move to break up Google may be ironic as the company faces more competition than ever.
• UK borrowing costs are rising, raising concerns about the impact on startups and the venture scene.
• The Regulatory Innovation Office aims to streamline approvals for new technologies, but its effectiveness remains to be seen.
• LPs are currently cautious about investing in venture capital, with a notable decline in interest in first-time managers.
• There are pockets of renewed interest from family offices looking to invest in emerging managers.
• European startups are increasingly raising significant capital, indicating a growing talent pool.
• Ownership and location are becoming less rigid as companies seek funding across borders.
• Despite challenges, the overall sentiment is that European venture is progressing positively.

Chapters
00:00 Introduction to the European VC Podcast
01:47 Nobel Prizes and AI Innovations
03:23 Regulatory Challenges and Market Dynamics
05:34 The Future of Google and Antitrust Issues
10:53 UK Economic Challenges and Startup Impact
19:06 Regulatory Innovation and Its Implications
22:34 LPs and the Future of Venture Capital
31:25 Ownership, Location, and European Startups

The Seed - Episode 11 - This week in Euro startup land - 29th Sep 29 Sep 202400:33:59

Summary
Dan and Mads discuss Europe's energy challenges, the need for more positive leadership, the future of remote work, the transformative impact of AI on society, and insights from the Foundations paper regarding the stagnation of the UK economy. They explore the implications of these themes on the future of technology, infrastructure, and economic growth.

Takeaways
Europe faces significant energy challenges to support AI growth.
Positive leadership is crucial for business morale and investment.
The return to office mandates - a step backwards or forwards.
AI is set to revolutionise err, everything.
The UK's complicated planning stifles investment.
Infrastructure projects in the UK are significantly more expensive than peers.
Real wage growth in the UK has been stagnant for years.
The Foundations paper highlights systemic issues in the UK economy.
Historical examples show that the UK can recover from economic downturns.
Optimism and strategic planning are essential for future growth.

Sound Bites
"How will Europe power the next wave of AI?"
"We need a positive message from our leaders."
"Is Amazon's return to office a step backwards?"

Chapters
00:00 Introduction and Overview of Topics
01:07 Energy Challenges in Europe: The Case of Three Mile Island
05:17 Positivity and Energy in the UK: A Call for Optimism
07:53 Amazon's Return to Office Policy: A Step Forward or Backward?
09:57 Chip Manufacturing in the UAE: Samsung and TSMC's Plans
11:52 The Future of AI: Predictions for 2030
16:34 Telegram's Concessions: Implications for Messaging Platforms
17:36 Meta's Orion Glasses: The Future of Human Connectivity?
23:16 Foundations Paper: Understanding the UK's Economic Stagnation
29:27 Unlocking Growth: The Path Forward for the UK

Keywords
energy, AI, leadership, remote work, UK economy, nuclear power, positivity, technology, infrastructure, productivity

The Seed - Episode 10 - This Week In Euro Investing and StartupLand22 Sep 202400:33:18

Summary
In this episode, Mads, Dan and Monik discuss the dynamics of startup funding, particularly the trend of startups moving from Europe to the US in search of better investment opportunities. They analyse the implications of recent US interest rate cuts on global investments and the challenges faced by the UK government in fostering a conducive environment for startups. The conversation also highlights Germany's new initiative to boost startup investments and the role of the EU Commissioner for Startups in enhancing the European startup ecosystem. Additionally, the hosts explore the importance of identifying economic proxies for startups and the delicate balance between technological innovation and government regulation.

Takeaways
•Why startups moved to the US for funding.
•How US interest rate cuts will stimulate global investment.
•UK government faces significant challenges in economic growth.
•Germany's WIN initiative aims to invest heavily in startups.
•The EU's new Commissioner for Startups could drive innovation.
•Economic proxies can indicate the health of startup ecosystems.
•AI regulation poses risks to innovation in Europe.
•Collaboration between government and startups is essential.
•Investment in technology is crucial for economic prosperity.

Chapters
00:00 Introduction to Startup Funding Dynamics
02:58 The Shift of Startups from Europe to the US
05:59 Impact of US Interest Rate Cuts on Global Investments
09:51 UK's Economic Challenges and Government's Role
15:04 Germany's Initiative to Boost Startup Investments
19:00 The Role of the EU Commissioner for Startups
24:11 Proxies for Economic Health in Startup Ecosystems
30:09 The Balance Between Technology and Government Regulation

The Seed - Episode 9 - This Week In Euro StartupLand15 Sep 202400:35:50

In this conversation, Dan, Mads, and Andrew discuss what's happened this week in the European startup ecosystem. The real value of events for investors and founders, highlights from the All In Conference, DeepMind's new AI system for protein design, productivity challenges in the EU, the future of innovation in Europe, and the impact of AI on SaaS. 

* Events can be valuable if approached strategically.
* AI is making significant strides in medical research and drug discovery.
* Fixing EU challenges with productivity and innovation.
* Does politics matter at these conferences? Should we care?
* DeepMind's AI system could revolutionise protein design.
* Klarna ditches SaaS for Ai.  
* The EU's real productivity dilemma

Chapters
00:00 The Value of Events for Investors and Founders
04:40 Insights from the All In Conference
10:18 The Intersection of Politics and Inspiration
13:38 DeepMind's Breakthrough in Protein Research
19:08 Mario Draghi's Vision for European Competitiveness
26:12 The Future of SaaS in the Age of AI

Keywords
events, investment, AI, productivity, Europe, DeepMind, innovation, Klarna, healthcare, technology, investing, VC

Upside #32 - Tech to kill, tech to heal.08 Mar 202500:47:33

Upside Podcast: Defence, Health Tech & The Future of European Venture

This week on Upside, Dan Bowyer (SuperSeed VC) is joined by Lomax (Outsized) and Peter Ward (Humanity) to dive into two major themes dominating European venture: defence and health tech. With Mads away running up hills in Spain with fellow VCs and LPs, the trio take a no-holds-barred approach to dissecting the latest developments shaping investment, technology, and geopolitics.

1. Welcome & Introductions (00:12)

2. Defence & European Venture (02:22)

  • The geopolitical impact of US halting aid to Ukraine: What does it mean for European defence startups?
  • The rise of defence ETFs and their influence on VC investment.
  • Trump, NATO, and the potential ripple effects on European security.
  • The growing relevance of Turkey in European defence strategies.
  • Europe’s defence budgets are growing, but how fast can startups access the market?
  • The challenge of military procurement and its implications for defence tech startups.


3. Private Capital & Defence Innovation (06:32)

  • The role of dual-use technology in military applications.
  • The ethical dilemmas of investing in defence technology.
  • Drone warfare: The boom in anti-drone and drone swarm tech.
  • Lomax’s insights on the procurement challenge and opportunities for startups.
  • Dan’s first-hand experience in Ukraine delivering medical supplies.


4. Trumponomics & European Startups (22:37)

  • Trump's proposed tariffs on the EU and potential supply chain shocks.
  • How this could drive inflation, stagflation, and impact fundraising for startups.
  • The anti-American sentiment in Europe and its impact on consumer and business purchasing decisions.
  • Opportunities for EU startups to capitalise on this shift.
  • Will founders move to the US earlier to escape potential trade barriers?


5. The Future of Health Tech in Europe (30:37)

  • A new breakthrough in immune system research: Could it revolutionise antibiotics?
  • The rise of AI in drug discovery and early diagnostics.
  • Humanity’s work with Imperial College London: Predicting disease and biological age with just four blood markers.
  • Personalized medicine: How it will transform healthcare systems.
  • The booming investment landscape: $7B invested in health tech in Europe last year vs. $23B in the US.
  • Neko Health, Function Health, and the billion-dollar Series A from Retro Biosciences.


6. Deals of the Week (44:31)

  • Alpine Eagle ($10M seed, UK): Drone blocking and attacking tech.
  • CloudSmith (Series B, Belfast): Cloud software security startup.
  • Quintexa ($175M Series F, UK): AI-powered anti-money laundering and fraud detection.
Upside #31 - The Grind is Back01 Mar 202500:53:33

Euro Grind, Google Grind, and Startup Hustle.

As normal we dig behind the headlines to discuss the real stories affecting European venture. With Dan Bowyer, Mads Jensen, Andrew Scott and Karin Nielsen.

The State of European Tech vs. the U.S.

  • Karin’s reflections on her trip to San Francisco and the stark contrast in optimism between the U.S. and the UK.
  • The resurgence of hustle culture in the U.S. and what Europe can learn from it.

Funding Gaps & European Venture Trends

  • Stripe’s annual letter highlights European productivity challenges and regulatory barriers.
  • The need for European capital market reforms to boost startup funding.
  • Discussion on whether Europe should adopt a ‘Buy European’ strategy.

AI Advancements & Enterprise Adoption

  • The launch of Claude 3.7 by Anthropic and GPT-4.5 by OpenAI: Are these models delivering real breakthroughs?
  • China’s AI strategy and the impact of DeepSeek’s pricing strategy on global AI competition.
  • The challenges enterprises face in adopting AI, from legacy systems to regulatory concerns.

The Future of Work & The ‘Grind’ Debate

  • Sergey Brin’s push to bring Googlers back to the office: Should startups embrace remote work or office culture?
  • The debate over whether European startups work hard enough and whether remote work fosters or hinders hustle.
  • Insights from Karin on how remote-first startups can thrive with the right culture and tools.

AI’s Impact on Venture Capital

  • Will AI-driven deal sourcing make VCs obsolete, or will brand and relationships matter more than ever?
  • The shift towards hyper-personalised outreach and the rise of X (formerly Twitter) as a key VC-founder networking tool.
  • Why AI-powered investing will still require human intuition to identify outlier founders.

Deal of the Week: Lovable

  • The meteoric rise of Lovable, Europe’s fastest-growing startup.
  • From launch to $17M ARR in 18 months: What’s behind its explosive growth?
  • The future of AI-powered no-code solutions and their impact on SaaS.
Upside #22 - The News Behind 2024's Biggest Tech Headlines22 Dec 202400:33:45

In this episode we review significant events of 2024, focusing on the rise of AI, the challenges Europe faces in building its own AI infrastructure, and the political and economic landscape shaped by the recent elections. We chat venture capital trends, the impact of geopolitical shifts in the Middle East, and the future of TikTok amid national security concerns. 

  • Altman and Musk face off while Elon builds Colossus.
  • The AI war heats up in big tech 
  • Is Labour competent enough to build business in Britain?
  • Should Europe build chips?
  • The Bitcoin Act.
  • Will Trump Switch us off?
  • The Trump sugar high. Coming to Europe?
  • Will TikTok go down to Chinatown?
  • More M&A means more business, recycling, investment
  • Agentic workflows to impact the Enterprise
  • More IPOs in 2025.
  • The geopolitical landscape in the Middle East & implications for us all.
  • 2024 inc VC was volatile but performed well. How?

00:00 2024: The Year of AI Ascendancy - Musk builds Colossus.
05:48 Europe's AI Infrastructure Challenge
12:12 Political Landscape and Economic Predictions
18:03 Venture Capital Trends in 2024
24:02 Geopolitical Shifts in the Middle East
29:58 The Future of TikTok and National Security
35:58 Looking Ahead: Startups and IPOs in 2025

Upside #21 - UK Govt to act like a startup? Why China's downturn matters here. The EU Brain drain - is it real? A quantum leap, and green steel.15 Dec 202400:29:34

Mads and I chatting this week about all things VC, investing, startup affecting Europe,

  • Can the UK govt really think like a startup? Should it?
  • The British DOGE.
  • No one in the Labour govt has ever run a business. Matter?
  • Why China's downturn will batter Europe.
  • The European brain drain - is it real?
  • Freedom of movement, is it coming back?
  • Quantum is here, or is it.
  • The old guards are coming out to solve Quantum.
  • Can startups survive red ocean? If so how?
  • Execution vs Novel.
  • European startup of the week - Stegra.
  • Why green steel is so important.
The Seed #20 - Euro-Autocrash, Euro-(no)Doom, Europe's 1st Trillion $tartup, Musk v Altman10 Dec 202400:41:05

We're in a studio this week, sounding joojie. Mads and I discussing this week's news, views and thoughts around Europe, startup, and investing. What's moving the needle, what's not, and why.

The Decline of Europe’s Automotive Industry
◦ The shift from internal combustion engines (ICE) to electric vehicles (EVs).
◦ Why Chinese automakers are dominating global markets.
◦ Can Europe recover, or is the industry destined for slow decline?

Trillion-Dollar Companies: Can Europe Compete?
◦ Why Europe has yet to produce a trillion-dollar company.
◦ Strategic importance of big tech companies for economic growth and national influence.
◦ Key sectors that could drive Europe's first trillion-dollar success: biopharma, quantum technology, and energy.

China vs. the US: The Resource War
◦ The implications of China restricting exports of critical metals like gallium and germanium.
◦ How this trade war impacts Europe and global supply chains.
◦ The importance of resource independence and domestic production.

The AI Cage Match: Elon Musk vs. Sam Altman
◦ The history of OpenAI, its pivot to a for-profit model, and Musk’s fallout.
◦ The rise of XAI and the battle for AI supremacy.
◦ Will Nvidia face real competition in the AI chip market?

Founder Corner: The Psychology of Founders
◦Insights into founder breakups and the challenges of building a startup.
◦How Europe’s culture of risk aversion may hinder innovation.
◦The importance of supporting founders to build resilient, long-term businesses.

Bitcoin and Morality
◦A heated debate about the ethics of Bitcoin and its role in the economy.
◦Speculation, regulation, and the future of cryptocurrencies.
◦Does Bitcoin represent humanity’s worst impulses, or is it a driver of innovation?

The Seed #19 - Body scans yay nay, ChatGPT is 2 - now what for LLMs, are psychedelics back?01 Dec 202400:37:51

1st Dec 2024 - This week in Euro VC.

Super happy to have Lomax from outsized.vc with us today bringing an extra edge of health tech. 

Dan shares his experiences with nekohealth.com full body scanning. 

What's the future of preventative scanning, when will it be NHS ready and what opportunities are there for startups.

ChatGPT is 2! How OpenAI stole the march on Google, who invented the transformer.

LLMs - what's next and from whom.

Northolt. Gah. Into administration she goes - $21bn spent but is it all lost?

Recursion and ExScientia - how they bowed out stage right with a whimper.

Are psychedelics back? Will RFK open European doors?

Cradle Bio - Boom! Massive series B - bring on Europe!

The Seed #18 - Slush worth it? Bitcoin and morality. Anthropic with $4bn. Peak AI?24 Nov 202400:32:54

Summary
Dan and Mads discuss key developments in European venture capital, focusing on the recent Slush event, the implications of Bitcoin hitting $100k, Anthropic raising $4bn, the volatility of Bitcoin - what is it and what will it become, Klarna's US IPO, does Europe need it's own search engine? Are we at peak AI?

Takeaways
Slush is great, founders focused, 13,000 attendees.
Bitcoin to hit $100k? But it's what? And is it good for us?
Anthropic raises $4bn but are we at peak AI?
Klarna - Europe's exceptional founders have nowhere to go but the US
Revolut gets its UK license and is after you mr big bank.
Does Europe need its own search engine? Howabout no.

Chapters
00:00 Insights from Slush: A Major European VC Event
09:00 The Future of Bitcoin and Government Regulation
16:06 Challenges in AI Development and Data Limitations
22:54 Local vs Global Search Engines: A European Perspective

The Seed #17 - AI in real money, Identity politics is dead, M&A up, Bitcoin up. Humanity down.12 Nov 202400:27:03

This week in European VC - Dan and Mads explore the real revenue generated by AI startups, not hAIpy at all, no one went to COP29, the EU startup passport is arriving much sooner than anticipated, Germany's instability as an opportunity, AI is programming, insights from a recent MIT report on material science, and the global and local economic ramifications of Trump's administration. 

The average time for an AI startup to hit $1M in revenue is 11 months.
COP29 has seen a lack of attendance from major world leaders.
The EU startup passport aims to simplify regulations for startups.
Germany's government collapse could lead to more European reforms.
AI is 25% of coding at Google.
It's proven - AI significantly enhances productivity in material science.
Trump's election results. His focus on economic issues won over identity politics.
Increased M&A activity in 2025. Bitcoin up. IPOs up. Climate and humans be damned.
Startups will find new opportunities in this changing global landscape.

Chapters
00:00 AI Startups: Real Revenue vs Hype
05:47 EU Startup Passport: A New Era for Entrepreneurs
11:17 AI in Code: The Future of Software Development
17:04 Trump's Election: Implications for Global Economy
22:32 Opportunities and Challenges for European Startups

Show Notes and links

Dan - AI start-ups generate money faster than past hyped tech companies - 
https://www.ft.com/content/a9a192e3-bfbc-461e-a4f3-112e63d0bb33 

Average time  for an AI company to hit $1m is 11 months. SaaS is 15.

Cursor grew from $4M ARR to $4M/month in less than 12 months. AI is not just hAIpe - https://www.arr.club/signal/cursor-arr-at-50m-growing-crazy-from-4m-in-april 

AI vs SaaS Growth: AI start-ups reaching $30 million in annual revenue do so in about 20 months, five times faster than earlier SaaS firms.

Global Demand: Roughly 56% of AI companies’ revenue comes from international markets, with substantial purchases in regions like Singapore and Iceland.

Notable Examples: OpenAI, ElevenLabs, and DeepL are examples of successful AI companies. OpenAI’s ChatGPT became the fastest-growing consumer app, generating $3.6 billion in annual revenue despite high operational costs.

COP29 - none of the big wigs are there - Forty-eight fewer heads of state are addressing COP29 than last year. Xi Jinping and Joe Biden—presidents of the two biggest oil-producing countries - won’t be there. Russia not there. What will this mean for startups?

https://www.bloomberg.com/news/articles/2024-11-11/cop29-negotiators-agree-on-some-rules-for-global-carbon-market?sref=KkPzpZvz&srnd=homepage-americas

New UK target for 81% emissions cut by 2035 https://www.bbc.com/news/articles/cx2ny8zndpxo

The new EU Startup passport
Announced by Ursula von der Leyen - EU Commission President

German Government has collapsed
Scholz calling for new elections

AI Now Writes Over 25% of Code at Google - 
https://uk.pcmag.com/ai/155094/ai-now-writes-over-25-of-code-at-google

Google Confirms Jarvis AI Is Real by Accidentally Leaking It - 
https://gizmodo.com/google-confirms-jarvis-ai-is-real-by-accidentally-leaking-it-2000521089?

Artificial Intelligence, Scientific Discovery, and Product Innovation* by Aidan Toner-Rodgers† at MIT
https://aidantr.github.io/files/AI_innovation.pdf

- AI automates 57% of idea-generation tasks, allowing scientists to focus on evaluating AI-suggested compounds.
- It reduces repetitive, low-value research directions.
- AI-assisted researchers discover 44% more materials, leading to a 39% increase in patent filings and a 17% rise in product prototypes that incorporate these materials.

Trump globally. Trump administration to the UK and Europe - what next?

The Seed #16 - Trump in CHIPS out - UK CHIPS in? Burnout Stats and Buffet Cashes Out06 Nov 202400:30:21

In this conversation, Dan and Mads discuss what Trump will and won't do now he's in. IS CHIPS out? As Europe's CHIPS is in? UK's investment woes with such little support from Govt. Warren Buffett cashes out - Apple now. Is the market over priced? GS thinks so. AI disrupting big tech gets bigger. Founder burnout is back, bigger and badder so what role should venture capitalists play?

Full contents

  • Drama drama - The 2024 election will have significant implications, for all.
  • Trump's policies will open the M&A landscape.
  • The CHIPS Act - Will he really repeal it?
  • Europe's semiconductor strategy vs the U.S.
  • Will the UK government finaaalllly get round to prioritising investment? 
  • Warren Buffett's cash out hits $325bn 
  • The AI race is poking Google in the eye, again.
  • Startup founder burnout goes big 
  • Building a VC backed startup is, just, brutal. Know the beast.
The Seed #15 - The UK Budget, ARM vs NVIDIA, Germany's Non-Profits, Where Are all the Investors Going?30 Oct 202400:34:30

In this conversation we dig into the UK's Autumn Budget - it's just *not* investor or build friendly - gah, Germany launches more non-profits, will ARM enter the AI arms race *against* it's own customers?!... and yet *more* regulation - this time in the beautiful game, but why that matters.

Chapters
00:00 Juvenile Politics
00:27 UK Autumn Budget: Invest Invest Invest! Ok, don't then.
04:22 Economic Growth Needs the Right Frameworks
08:12 The Future of Startups in an AI-Driven World
13:09 ARM vs Nvidia: Arm Getting in the Arms Race?
21:40 Volkswagen's quality problems
25:27 Football Regulation. Hang on. I thought you said less regulation?

Upside #30 - Can Europe win AI, Fusion & Quantum?22 Feb 202500:44:02

In this episode of Upside, hosts Dan and Mads from SuperSeed are joined by Ben Prade, Partner at GP Bullhound. Topics covered:

State of European Venture Capital 
Geopolitics & VC - the Munich Security Conference, JD Vance, European autonomy in defence and tech, China filling the void

VC Fundraising & LPs
AI and defence are hot baby! Shift from US pension to government cash, VCs must engage in ecosystem building, economic policies influencing VC strategies.

The Future of European VC 
European VC has outperformed the US in IRR (20.8% vs 18.2%) over the last decade. We're nailing AI, Fusion and Quantum.

Quantum: Hype vs Reality
Microsoft's Majorana 1 Quantum Chip, cautious optimism, power PR and viable quantum computing by 2030.

Grok 3 
Grok 3 is out, speed and benchmarks vs Claude and GPT 4.5.

Fusion
France’s CEA West Tokamak reactor sets a new record with 22 minutes of continuous fusion, limitless clean energy, realistic timelines for commercial fusion.

Startup Funding Dynamics - Go big early?
Peter Walker’s Carta report:
Theory 1: AI reduces startup costs, meaning less = more.
Theory 2: AI increases competition, making capital more crucial for scaling.
= Seed Strapping

Asteroid Mining 
Spotlight on Karman Plus, autonomous asteroid mining. Government funding in space.

Upside #29 - Le Summit, Le Chat, Le $100bn15 Feb 202500:37:08

Upside #29 - Le Summit, Le Chat, Le $100bn

LP Blind Spots
LP in Asia with 3000 managers but only 3 in Europe—why?
European VC viewed as a "blind spot" by many investors in Asia and the US.
The need for European investors to bridge the perception gap.

Deep Dive: The France AI Summit
Focus on "Inclusive and Sustainable AI."
100 countries in attendance, 61 signed the agreement—but UK and US did not.
Discussion around ethics, accessibility, and the role of global AI governance.
JD Vance’s speech highlighted US dominance and reluctance to align with EU directives.
Debate: Was it the right call for the UK not to sign?

EU’s €50B AI Investment
US announced $500B AI initiative; France followed with €109B.
Comparison between Macron's AI plan, UK AI strategy, and Bidenomics.
The importance of aligning private investment with government funding.

Mistral’s ‘Le Chat’ AI Model
French AI company Mistral launched "Le Chat."
Designed for speed but criticised for lacking depth and innovation.
Open-source AI as Europe's potential advantage in the global AI race.

AI Corner
GPT-4.5 expected within weeks, the last non-chain-of-thought model.
Grok 3 by XAI (Elon Musk) in development, set to challenge OpenAI’s dominance.
Open-source AI progress making Europe a contender in the AI space.

Interest Rates and UK Economic Outlook
Bank of England’s 25 bps rate cut—will it impact startups and investments?
UK growth forecast halved to 0.75%.
Concerns about stagflation, job losses, and productivity decline.
Can AI be the key to unlocking efficiency in government services?

AstraZeneca Vaccine Plant Withdrawal
UK government cut state aid from £90M to £40M.
AstraZeneca chose to invest elsewhere. Ble.
A significant loss for Liverpool’s economy and UK biotech sector.

Deal of the Week
Tines (Ireland) raises $125M Series C, becoming a unicorn.

Final Thoughts
Optimism about UK and European innovation despite economic hurdles.
Encouraging bold policy decisions and strategic AI investments.
"Let's start doing."

Upside #28 - Inside no.10, Going Nuclear, UK merely a startup incubator? European (lack of) sovereign wealth?08 Feb 202501:01:16

In this episode, Dan, Lomax, and Mads dive into a packed agenda spanning tech earnings, European venture dynamics, government policies on AI and nuclear energy, and the debate over whether Europe—or the UK—could (or should) define its own version of the “American Dream.” Mads shares insights from his recent visit to Number 10 Downing Street to discuss the UK’s AI strategy, and Lomax highlights a series of notable European health tech deals.

Welcome & Introductions
• Dan kicks things off with a check-in on what’s happening in Lisbon, London, and beyond.
• Lomax is monitoring global political drama (particularly in the U.S. and Europe).
• Mads teases big announcements out of Number 10 regarding AI.

Tech Earnings & Market Sentiment
• Palantir reports bullish earnings; stock jumps ~24%.
• Google’s cloud growth disappoints vs. analyst expectations; capital expenditures on the rise.
• AMD and ARM under the spotlight—concerns over data centre growth.
• ASML and Spotify highlight strong European tech performance.
• January inflows into European stocks reach 25-year highs, briefly outpacing US markets.

Cherry Ventures’ $500M Raise & Europe’s VC Landscape
• Cherry Ventures closes its fifth fund, demonstrating how larger European VCs continue to mature.
• Discussion on the overall trend: Big name funds attracting more capital, mirroring the U.S. “flight to quality.”

German Elections & Political Shifts
• The rise of the far-right AFD (Alternative für Deutschland) in the polls.
• Potential implications for tech talent and immigration policy.
• Broader context of populism in Europe and the struggle for pro-tech growth policies.

The UK’s Nuclear Push
• New moves to accelerate nuclear power plant approvals and the pivot to small, safe reactors.
• How nuclear energy ties in with AI (data centres needing massive, stable power sources).
• Debate over planning red tape vs. the urgency to bolster UK’s energy security and cut costs.

The Number 10 AI Plan (Mads’ Visit)
• Mads shares first-hand insights from meeting with UK government officials, including Keir Starmer.
• Adoption of Matt Clifford’s 50-point AI plan and the promise of government as an “early customer.”
• The challenge of scaling AI talent in a post-Brexit environment—and how to attract global talent.
• Pension reform, government procurement, and the push for overall efficiency gains in the public sector.

Is Europe Just an “Incubator” for the US?
• Analysis of new research suggesting fewer startups relocate to the US than expected—but those that do raise 3x more capital.
• Role of large European funds in combating early acquisitions and supporting founders to scale.
• The example of ARM and its journey from European tech champion to global powerhouse.

Trump’s Proposed US Sovereign Wealth Fund
• Contrasting with Norway’s $1.5 trillion Government Pension Fund Global and Singapore’s GIC.
• Questions around how a country with high debt (like the US) might run a sovereign wealth fund.
• Potential lessons for European nations and the risks of politicising large capital pools.

Deals of the Week
• Health Tech Highlights:
◦UK cancer detection startup See the Signs secures seed funding led by Khosla.
◦ IVF funding platform Gaia raises a strong Series A.
◦ Spanish AI imaging startup Cuban nabs a $50M Series A.
• ARM & Ampere rumour: possible acquisition to expand ARM from IP licensing into actual chip manufacturing for data centres.

Looking Ahead
• Mads: Speaking at local schools on entrepreneurship, then multiple board meetings.
• Lomax: Closing an investment in a space-tech company and working on a significant Series B funding.
• Dan: Potential trip to Finland to explore a diagnostics startup focusing

Upside #27 - You say to NATO, EU defence up in arms, UK growth rhetoric vs reality, Deepseek deep dive.01 Feb 202501:00:43

Hosts: Dan, Andrew, Mads and Lomax

The Future of Defence in Europe - Show tRump the monnaayyyy
- NATO defence spending push: Lithuania and Estonia commit to Trump's 5% target.
- Europe's over-reliance on US defence infrastructure – time to build independent capabilities?
- Startups and venture capital in defence: The next big opportunity?
- Should Europe follow the US model of defence tech innovation? Can it go private?

UK's Wonky Economic Growth Strategy
- Rachel Reeves' "turbocharging growth" plan – is it more rhetoric than reality?
- The role of the National Wealth Fund and the Office for Investment in boosting UK infrastructure.
- The Heathrow third runway debate – long overdue, too far away, or plane misguided?
- Unlocking UK pension funds for investment – real impact or just political showmanship?
- How the UK can actually foster innovation and become the "next Silicon Valley." Oxford <> Cambridge Arc.

Europe's AI and Investment Updates - Is Quantum back?!
- OpenAI launching ChatGPT Gov: What does this mean for government AI adoption?
- Apple’s position in the AI race – overlooked but strategically poised?
- 11Labs raising $250M at a $3B valuation – Europe's AI voice technology rising.
- Quantum computing’s resurgence: Alice & Bob, Quantinuum IPOs, and Europe's role.

The DeepSeek Disruption - The numbers just don't add up
- China's DeepSeek AI model making waves – is it a game-changer or just a media frenzy?
- Claims of IP infringement vs. technological innovation – how much did they really borrow? The 'distillation' woogabooga
- The efficiency leap: What cost $5 billion for OpenAI cost DeepSeek only $5 million?
- The geopolitical impact: US-China tech war escalates, export restrictions, and AI as a national security concern.
- What this means for European AI: Why wasn’t a European company leading the charge?

The Rise of Political Discontent - Young'uns want us to be like China
- 52% of Gen Z in the UK favouring dictatorship – a reflection of frustration or a dangerous trend?
- Elon Musk’s AFD rally appearance in Germany – should we be worried?
- The broader implications of political shifts on global investment and innovation.

The team close reflecting on the balance of optimism vs. realism in European tech and investment. What they're up to this week and to be more.... Merrricaan!

Thanks for tuning in! See you next week.

06:00 The Role of Startups in Defence
12:00 Pension Reforms and Investment Opportunities
18:10 AI and Innovation in Government Spending
38:24 The Urgency of AI Implementation
46:12 The Implications of DeepSeek's Innovations
57:10 Funding Trends in European AI Startups
01:02:32 Gen Z's Political Sentiments and Future Outlook

Upside #26 - Operator operates, AI workforces launch, More runways = what? Trumps first days and Stargate.26 Jan 202500:51:58

This week Dan, Lomax, and Ferdinand discuss European startup investing, focusing on the impact of AI, job cuts at Meta and what that really means, commercial changes at the head of the UK competition regulator, airport expansions mean what and for whom exactly, plus a meaningful M&A uplift in activity.

How can we not talk about Trump's first few days and knock on policies for our European landscape, the implications of Doge and the Trump Coin grift. They discuss the Stargate AI project which is just massive - if it comes off, and the innovative healthcare startup Neko.

On the show...

OpenAI Launches 'Operator'
Operator: First full-control AI agent. The Browser within the browser with full 'agent' control. Accessible only via Pro plan ($200/month). Initially US-based; European launch delayed per OpenAI CEO Sam Altman. Potential to redefine AI agents—parallels drawn with Apple’s strategic moves.

Meta Cuts 5% Workforce (3,600 Jobs)
Debate: Necessary efficiency or signs of struggle in boom times? Looks like just an AI push. Or hiding DEI and sustainability push out? The implications for AI-driven workforce restructuring are happening right now.

UK’s CMA Leadership Shakeup
New Chair: Doug Gurr (ex-Amazon). Shift from consumer protection to economic growth focus. Goal: Accelerating UK commerce. Red tape cut? Let's see.

Heathrow Expansion Resurfaces
Ministers endorse a third runway proposal. Estimated economic boost: £47bn–£143bn by 2060, with 27k new jobs. Controversies around environmental and regional impact.

European M&A Activity Rebounds
H1 2024 deal value up 31% YoY (€439 billion). Venture capital-backed M&A sees 46% growth in Q4 2024. Future outlook tied to IPO resurgence and eased regulations.

Trump’s First Days
Executive Orders galore, Biden’s rescinded. Threats of tariffs, and owning Canada. Tax breaks for US-built goods. What are the global implications and for the UK and EU economies.

DOGE(Y)
Looks bipartisan and who doesn't want more efficiency in govt? Targets $2 trillion savings by 2036 — ambitious or unachievable? And where's Vivek?

Stargate AI Project
$500 billion US investment in AI infrastructure/data centres (Texas). Partnering with Microsoft, Nvidia, Oracle, SoftBank, Arm. But exclusively serving OpenAI? No wonder Elon is fizzing.

Company of the Week: Neko the health scanning startup from Daniel Ek.
Series B closed another $260mn. Dan thinks the future of healthcare.

00:00 Introduction to European Startup Investing
02:54 Exploring AI Agents and Their Impact
05:59 Meta's Job Cuts and AI Efficiency
08:56 UK Competition Regulator Changes
11:56 Airport Expansion and Economic Growth
14:59 M&A Activity in Europe
18:11 The Influence of Trump's Policies on Europe
29:51 Bipartisan Efforts and Government Efficiency
31:39 Geopolitical Context and Market Confidence
33:42 Doge and Economic Implications
36:16 The Rise of Trump Coin
40:11 Stargate AI Project: A New Era
47:55 Neko's Series B and the Future of Healthcare

Upside #25 - UK IPOs Rise, AI Opportunities Action Plan, A Jurassic Lark & White Hydrogen19 Jan 202500:43:42

In this episode, we dive into the future of London's IPO pipeline, the UK's ambitious AI opportunities action plan, and Colossal Biosciences' fascinating mission to resurrect extinct species like the woolly mammoth. We also explore the role of white hydrogen as a potential energy frontier and discuss Europe's rising share in global tech value. From market insights to groundbreaking technologies, this episode has something for everyone.

Key Topics

London’s IPO Revival

  • 2024 marked the worst year for London IPOs, even below 2009 levels.
  • Analysing the pipeline for 2025, featuring companies like Shein, Starling Bank, Zopa, and Ebury.
  • Challenges: Lack of startups scaling to IPO status and low appetite for equities among pension investors.
  • Historical context: 136 IPOs in 2014 vs. 6 in 2024.

The UK’s AI Opportunities Action Plan

  • Highlights of the government’s action plan for AI growth.
  • Focus on scaling pilots nationally and creating datasets leveraging institutions like the BBC for data.
  • Challenges: Addressing copyright rules, data funding, and fostering founder-friendly ecosystems.
  • Insight on talent, funding, and tax hurdles.

Company of the Week: Colossal Biosciences

  • The mission to bring back the woolly mammoth, Tasmanian tiger, and dodo bird using CRISPR gene-editing technology.
  • Ethical and practical questions surrounding de-extinction and re-wilding.
  • Implications for biodiversity and conservation.

A New Energy Frontier? White Hydrogen

  • Could this be the next renewables frontier for startups?
  • Exploring naturally occurring, renewable white hydrogen as a power source.
  • Challenges in storage, transportation, and extraction.
  • Potential game-changer in the global energy mix if scalable solutions emerge.

European Tech Growth

  • Europe’s increasing share of global tech value, now at 18-19%. Up from 5% three decades ago.
  • Insights from CEO Yoram Wijngaarde and Dealroom’s data on tech enterprise value creation since the 1990s.

Keywords
IPOs, London, AI Opportunities, Venture Capital, Regulatory Challenges, Tech Ecosystem, Government Policy, Investment, Infrastructure, Innovation, economic challenges, woolly mammoth, hydrogen energy, energy innovations, European tech, deep tech investment, political impact on technology

AI Summary
In this conversation, Dan, Mads and Andrew discuss the current state of IPOs in London, the challenges and opportunities within the regulatory framework, and the ambitious AI Opportunities Action Plan led by Keir Starmer. They emphasise the importance of government support, access to talent, and the need for a robust infrastructure to foster innovation in the UK tech ecosystem. The discussion highlights the necessity for policy changes to attract founders and investment, ultimately aiming to position the UK as a leader in AI and technology. In this conversation, the speakers discuss various innovative solutions to economic challenges, including the Mansion House compact and the need for a talent magnet in the UK. They explore the exciting yet controversial project of reviving extinct species like the woolly mammoth through gene editing. The discussion shifts to the potential of hydrogen as a clean energy source, addressing its challenges and the need for strategic investment in energy. The speakers also highlight the growing tech landscape in Europe and the importance of deep tech investment, while reflecting on the political changes that may impact technology and innovation.

Upside #24 - Fact Check This, European Unicorns, Should Govt Invest in Startups? Digits For Who?11 Jan 202501:02:08

In this insightful episode, Dan, Mads, and Lomax tackle some of the most pressing topics in tech, venture capital, and global business, diving into issues like Europe's chip dependency, the evolving role of AI in VC, the future of social media moderation, and the rising stars in the European startup scene.

Europe’s Semiconductor Struggles
The problem: Europe's lag in semiconductor production compared to global competitors like the US and China. 
Key insights: Germany's halted Intel plant and Europe’s high energy costs exacerbate its strategic vulnerability. Lack of coordinated funding—only €4 billion from Brussels compared to $142 billion in China.

The Role of AI in Venture Capital
Future of VC: Will AI become a co-pilot, augmenting human decision-making, or could we see fully automated "Quant VC"? 
Predictions: AI can streamline processes like sourcing and due diligence. Human interaction remains crucial for founder evaluation and post-investment support.

Social Media, Free Speech, and Moderation
Meta’s Shift: Meta moves away from fact-checking in favour of community notes in the US but not the EU due to stricter regulations. Broader themes: The challenges of moderating social platforms in a way that balances free speech with preventing harm.

European Startups and Unicorns
Positive trends: Europe saw 13 new unicorns in 2024, doubling from the previous year. Highlights include: Diverse representation: Companies from across sectors and countries. Notable names: Kraken (Octopus Energy's SaaS platform) and Bending Spoons (creative suite apps). 

Government’s Role in Venture Capital
Debate: Should government funding for startups taper off as private markets mature? Key takeaways: Europe needs institutional capital to match the US. Government initiatives like the British Business Bank’s Enterprise Capital Fund have shown positive results. 

NVIDIA and the Future of Computing
Jensen Huang’s unveiling of Digits, a $3,000 AI supercomputer for developers. 
Discussion on Moore’s Law breaking down and NVIDIA’s innovative approach to integrated computing systems.

Closing Thoughts
The evolving tech and VC landscape demands adaptability from all players. 
Europe must focus on creating favourable conditions for founders to build globally competitive startups. Excitement for 2025 as AI and foundational tech continue to reshape industries.

With Hosts
Dan: The optimist, ready to embrace AI's potential in VC.  
Lomax: The realist, emphasising the importance of human connection and strategy.  
Mads: The strategist, diving deep into the broader implications of industry trends.  

00:00 Introduction and Podcast Overview
06:13 Intel's Challenges and European Dependency
12:01 The Evolution of Free Speech on Social Media
18:05 Anthropic's Growth and Valuation in AI
32:26 The Future of Open Source and AI Funding
39:36 Government's Role in Venture Capital
53:56 Success Stories in the UK Startup Scene

Tune in next week for more insights into the world of tech, startups, and European venture capital! 

Upside #23 - Some not so obvious predictions for 202504 Jan 202501:02:17

Overview: In this episode of Upside, hosts Dan Bowyer and Mads Jensen, along with guests Andrew Scott and Lomax Ward, delve into their 8 bold predictions for 2025. 

Covering everything from AI and space tech to geopolitical tensions and venture capital trends, they unpack what’s on the horizon for tech, business, and venture in Europe and beyond.

2025 Predictions and Discussions:

1. Apple will win AI
2. Open AI will be dethroned 
3. Conflict with China
4. Defence Tech will boom
5. EU and UK will wake up and focus sovereign control on AI, Quantum and Space  
6. Space tech will really lift off 
7. US heads into recession 
8. M&A up IPOs up

00:00 Introduction to Upside and the Future of AI
02:46 Apple's Potential win in Consumer AI
06:11 OpenAI dethroned? Leadership and Future Challenges
11:49 China, geopolitical Implications of AI and Defence
23:52 Defence Tech Investment will boom
31:17 Hardware isn't always bad for VCs
32:14 UK and EU Sovereign Control and Technological Progress in 2025
33:39 The Importance of AI, Quantum Computing and Space to Europe
35:36 Space Tech really lifts off in 2025
38:26 Space Manufacturing and 'Why' Exploration
42:17 Timings and Market Predictions
51:33 The State of European Venture Capital
54:26 VC and the Role of Technology in Economic Growth
57:15 M&A and IPO Predictions for 2025

Key Topics Discussed:

Apple’s AI Strategy
Dan predicts Apple will dominate consumer AI by leveraging its ecosystem, resources, and loyal fan base. Mads questions whether Apple has lost its innovation edge and explores what "winning" consumer AI means.

OpenAI's Future
OpenAI faces challenges as competitors like Google, Anthropic, and XAI push forward. The panel discusses leadership struggles, funding needs, and the possibility of new technologies dethroning OpenAI.

Geopolitics and Defence
The impact of China's ambitions toward Taiwan and the West’s response. Defence tech as a booming sector, with increased NATO spending and opportunities in dual-use technologies.

Space Tech Expansion
Investment in space technologies continues, focusing on communication, defence, and manufacturing. The challenges of scaling space ventures and predictions for a more affordable and accessible space economy.

Economic Outlook for 2025
US economic trends point to a possible mild recession, while Europe faces stagnation due to political and economic challenges. Insights into concentrated stock markets, corporate performance, and venture investment trends.

M&A and IPO Resurgence
Pent-up demand for M&A deals and a likely reopening of the IPO market in 2025, with companies like Klarna leading the charge.

The European Venture Landscape
Challenges in scaling European startups and the need for founders to integrate US business DNA early. Calls for greater ambition to build trillion-dollar companies and reinvigorate Europe’s industrial base.

Memorable Quotes:

Dan Bowyer: “Apple’s ecosystem gives it a fighting chance to become the de facto standard for consumer AI.”

Mads Jensen: “Europe needs to back great founders and rebuild its industrial base.”

Andrew Scott: “Space tech is the future, but timing is everything. A lot of startups will fail before the sector truly takes off.”

Closing Thoughts:
The panel concludes with their personal focus areas for 2025, emphasising a love for early-stage European founders, the need for industrial reinvention, and how we can push boundaries in venture capital.

Upside #38 - Turkish Tech, Tough Love & Trends for '2519 Apr 202500:58:37

🎙 Upside: The Real Stories Behind European Venture

Hosts: Dan (SuperSeed), Lomax (Outsized), Andrew (7%),
Guest: Dilek Dayinlarli (Scalex Ventures)

⏪ In This Episode

This week on Upside, the gang is joined by the brilliant Dilek Dayinlarli, founder and managing partner at Scalex Ventures. Together, they unpack the latest headlines, industry trends, and ecosystem insights — with a deep dive into the fast-emerging Turkish tech scene.

🔥 What We Cover

⚡ Rapid-fire News Roundup

  • Murati raises $2B at $10B valuation — with talent from OpenAI and the Albanian PM cheering her on
  • Synthesia hits $100M ARR and partners with Adobe — a UK generative AI success story
  • Controversy as EIF refuses to back weapons/defence startups, even as Europe ramps defence spending
  • ASML's Q1: Strong results but order volumes down — signs of tariff jitters?
  • Figma confidentially files for IPO, bucking the trend
  • Hugging Face acquires a French humanoid robotics startup
  • Dollar drops: good for European stocks, not so good for US VC-backed markups
  • UK's bid for a piece of the $500B Stargate AI data centre project
  • New Finnish startup hub Maria 01 scaling up to 70K sq ft — the Paris Station F playbook

📈 Reports & Market Trends

  • Dealroom x HSBC Q1 Report: UK startups raised $4.2B in Q1 2024 - led by healthtech, with outsized deals like Isomorphic ($600M) and Vediva ($400M)
  • Concerns over UK IPO pipeline - will LSE stage a comeback?
  • The "founder flywheel" is spinning: UK seeing post-exit talent build new ventures
  • Big players still dominate fundraising: EIF, British Business Bank, British Patient Capital lead LP activity

💬 Big Conversations

  • Liquidity crisis in European VC: money going in, but exits not keeping pace
  • Why mid-sized exits matter more than ever
  • Capital efficiency in emerging markets vs. “go big or go home” mentality
  • Can European VCs stomach the high-stakes bets their founders need?
  • Secondary markets & the art of managing the “middle third” of your portfolio

🌍 Spotlight on Turkey Dilek brings us into the fast-growing Turkish tech ecosystem:

  • From $10M invested in 2012 to $2.6B+ in 2023
  • Gaming, fintech, defence tech, and B2B software leading the charge
  • Massive spillover effects: Peak Games and Getir have spawned 100+ startups
  • Entry valuations 60% lower than the US, and capital efficiency is key
  • Series B gap remains a challenge — but momentum is building
  • Turkey’s global diaspora plays a crucial role in scaling internationally

🏆 Deals of the Week

  • Dilek: Incident.io raises $62M Series B — another evolution in incident management
  • Lomax: Strava acquires Runna, a top 3 UK fitness app — a quick win, or premature exit?

🔗 Resources Mentioned

Upside #37 – Q1 2025 in Review + Tariffs & European Venture + Heads Down & Build12 Apr 202500:47:47

🎙️ Featuring:
Dan (SuperSeed VC)
Lomax (Outsized)
Andrew (7%)

00:30 – Klarna’s IPO Pulled & BNPL Under Pressure
Lomax reflects on Klarna pulling its IPO, amid turbulent markets and declining peers like Affirm. Is the buy-now-pay-later model starting to creak under macro pressure?

02:15 – Wave AI x Nissan: A Mega Auto Deal from Cambridge
A highlight for the UK: Wave AI’s $1.2B-backed AV tech lands a landmark partnership with Nissan for post-2027 production.

03:30 – Shopify's CEO Goes AI-First
Dan and Andrew react to a leaked Shopify memo urging teams to prove a task can’t be done by AI before requesting headcount.

05:05 – AI Futures Project: Black Mirror Vibes
A fascinating, speculative look at global AI scenarios via ai-2027.com — think Asimov meets geopolitics.

06:45 – Tariff Talk: Trump, Trust & Europe’s Wake-Up Call
Dan shares his eight theories on Trump's new tariff push, what it means for global trust, and Europe’s potential silver linings — including brain drain reversals and safe haven appeal.

10:45 – What Founders Should (and Shouldn’t) Do
Lomax: “Head down and build” remains the advice — though hardware startups at Series A/B should evaluate manufacturing strategy. Dan and Andrew agree: short-term panic isn’t the play.

14:45 – Hardware & Biotech: Sector-Specific Risk
How US-origin requirements, reshoring costs, and future pharma tariffs could force hard decisions on supply chains and capex.

17:45 – Market Reactions, Investment Shifts & “VC Panic”
From "RIP Good Times"-style memos to portfolio rebalancing — VCs are reacting in varied (and sometimes dramatic) ways.

22:15 – Report Review: State of Venture (CB Insights Q1 2025)

  • Global VC hit $121B — highest since Q2 2022
  • AI dominated with $40B for OpenAI alone
  • CVC activity dropped sharply, particularly in Europe & Asia
  • UK VC funding hit a 5-year low; Nordics and France on the rise
  • Fewer deals, bigger rounds, and a record 12 $1B+ M&A deals

27:15 – AI Bubble or Boom?
Dan & Lomax debate how long the mega-investments in gen AI can last. Andrew points to foundational tech (chips, infra, cyber) as the safer long-term bets.

32:30 – The Data Center Power Squeeze
Power scarcity is slowing new data center builds — particularly in Europe. Efficiency, not just scale, may be the next AI gold rush.

34:30 – Report Review: UK AI Sector (Tech Nation)

  • 2,300 AI startups worth $230B
  • $1B raised in Q1 2025
  • 76% of CEOs report positive impact
  • Growth capital & talent cited as top challenges
  • Policy still biased toward risk-aversion, not growth

38:45 – “The UK Thinks Small”
Lomax reads Barney Hussey-Yeo’s powerful critique of UK scale-up culture — a call for bigger ambition, smarter regulation, and less fear.

41:45 – What Needs to Change?
Andrew: “We don’t need more government-run funds — we need to unwind bad policies.” Immigration, pensions, and tax reforms are the real levers for growth.

44:15 – Deals of the Week 🚀

  • Polamist: European maritime defense tech
  • Green Jets: $7M electric jet engine raise
  • Jensen AI: Open-source distributed AI infra
  • Isomorphic Labs: $600M mega-raise led by US capital

46:45 – Final Thoughts
Despite the gloom around tariffs, IPO slowdowns, and policy inertia, Q1 shows Europe's tech scene still has major moves to make — especially if founders stay focused and regulators get out of the way.

Upside #36 - Tariffs - Liberating Europe - Pension Cha-Ching - “Peace” Tech05 Apr 202500:48:58

The shifting sands of geopolitics, defence tech, and AI — and what it all means for European startups, investors, and the broader ecosystem. From Germany’s defence splurge to Trump’s tariff theatrics and the commoditisation of LLMs, this one spans continents and controversies.

🧵 Topics Covered

  • Liberation Day (US):
    What does Trump’s tariff agenda mean for European startups? Is it just noise, or should we be worried about supply chain shock and retaliatory regulation?
  • European Defence Tech Boom:
    Germany’s lifted debt ceiling, tanks from Volkswagen, and defence ETFs surging 70-170%. Is this the economic unlock Europe’s been waiting for? Will the flood of money fuel true innovation, or just line the pockets of the usual suspects?
  • The Dual-Use Dilemma:
    AI startups becoming “peace tech” and the sudden defence pivot — are we heading for a repeat of the blockchain hype cycle? What does real opportunity look like in this space?
  • The AI Opportunity – or Not?
    Inspired by Nicolas Colin’s Drift Signal piece, the gang debates: Can Europe play a Japan-in-the-‘80s role in the AI era by winning at the application layer? Or is that wishful thinking?
  • Pension Power in VC:
    UK’s Mansion House Compact and the potential influx of pension capital into venture. Will it finally trickle down to true innovation?
  • TikTok Shop & Bezos’ Moves:
    What’s Amazon doing cozying up to Trump? Is TikTok’s forced sale the ultimate VC party round?

📊 Data Points

  • 0.007%: UK pension allocation to VC
  • 5%: Targeted allocation by 2030 under the Mansion House Compact
  • 25,000 parts: Average number in a modern car — a tariff tangle waiting to happen
  • Up to 170%: Growth in defence ETF performance
  • 400M: Capital raised by ISAR for its (exploding) rocket launch
  • 30 AI avatars: H&M replaces human models in new campaign
  • 50%+: US consumer share of GDP — explains the political calculus behind tariffs

📝 Show Notes Extras

  • 📖 Recommended Read: Nicolas Colin's “Who Will Be the Japan of the AI Era?” on Drift Signal
  • 📈 Theororm’s Report: Resilience sector is up 30% in Europe while overall VC is down 45%
  • 🧠 Trivia: The UK launched a satellite into orbit before the EU ever did… back in 1971. RIP Black Arrow.

🎙️ Upside: The Real Stories Behind The Headlines Affecting European Venture

Hosts:

  • Dan (SuperSeed VC)
  • Lomax (Outsized)
  • Andrew (7%)
     (Mads is away enjoying cherry blossoms in Japan 🌸)
Upside #35 - Spring Non-Statement, Project EurHope, Power of Brand 29 Mar 202501:00:23

🎙️ Upside: The Real Stories Behind European Venture

🎧 In This Episode

Join Dan, Lomax, and Mads, with special guest Alex Macdonald (founder of Sequel and investor), for an opinion-packed episode exploring:

🔦 Project Europe: Can It Save European Founders?

  • Alex shares his insider take as an LP in Project Europe — why he committed in 11 minutes, what makes it different, and how it's supporting founders before they become credentialed.
  • A passionate discussion around access, age, credentials, and whether early-stage capital is the bottleneck (spoiler: it isn’t).
  • Addressing the diversity backlash: Is it fair or misguided?
  • The million-euro question: How do we keep the next Revolut or Stripe in Europe?

💊 23andMe’s Collapse: The Business Model That Wasn’t

  • What went wrong with one of the most high-potential datasets in history?
  • Can health tech ever monetize patient data responsibly — and is “collecting data” a real strategy?

🧬 Data, DNA & Deletion Regret

  • Dan and Alex reflect on being early 23andMe users, deleting their data, and what happens when personal info is hacked.
  • Plus: A warning for startups assuming data is always monetisable.

📉 Spring Statement Reactions: A Missed Moment for Growth?

  • Rachel Reeves delivers... not much.
  • The group unpacks why cutting towards breakeven might not be the answer, and why we need fiscal stimulus, not fiddling.
  • Why “holding patterns” in policy could hurt more than they help.

🤖 AI Corner: DeepSeek vs. Gemini vs. Reve

  • OpenAI’s rumoured $40B raise (led by SoftBank)
  • DeepSeek’s new V3: small model, big results
  • Gemini finally feels usable — is Google back in the race?
  • Reve: The MidJourney killer?
  • Plus: The growing copyright vs. innovation battle in training data.

🚨 Startup Scandals & Fraud Watch

  • Builder.ai’s CEO steps down amid audit concerns
  • 11X under fire: Churn, fake logos, inflated ARR — or just messy scaling?
  • Where’s the line between "founder storytelling" and straight-up Theranos?
  • Dan dubs it: “The Orange Jumpsuit List” (aka Forbes 30 Under 30)

🇺🇸 US Brand Damage: Does It Matter in Europe?

  • From Trump to Tesla, has America’s “brand” hit long-term trouble?
  • Emotional vs. structural consequences
  • What defence tech buyers and governments are really worried about
  • Should Europe decouple — and can it?

💥 Deal of the Week

  • Marvel Fusion (Germany) raises €112M Series B/C for nuclear fusion tech
  • A rare bright spot for European deep tech growth capital

📌 Highlights

  • “Europe doesn't lack founders. It lacks belief.” — Alex Macdonald
  • “23andMe had 15 million people's DNA and still couldn’t build a business.” — Lomax
  • “Rachel Reeves is doing the startup equivalent of multiple shallow layoffs.” — Dan
  • “Failure is a feature, not a bug. Let a thousand flowers bloom.” — Mads
  • “Consumers might forget. Governments won’t.” — Lomax on US brand damage
  • “Where is the money? Still a good question.” — All

02:04 – Europe’s Biggest Company Is… SAP?
03:25 – 23andMe Files for Bankruptcy
07:33 – Project Europe Deep Dive
25:08 – Spring Statement Reactions
34:29 – AI Corner - deep seek, Gemini and Reve
42:15 – Startup Scandals
48:52 – Brand Damage
58:52 – Deal of the Week

Upside #34 - Filthy Food, AI Jesus, 7pm Bryan and Startup Spies.22 Mar 202500:48:45

Hosts: Dan, Lomax (Outsized), Andrew J Scott (7%), Mads (SuperSeed VC)
Runtime: ~48 minutes
Topic: Markets, M&A, AI mayhem, longevity hype, startup espionage — and a little bit of Bryan Johnson's bedtime routine.

🔍 This Week on Upside:

We’re going full spectrum this week: markets moving, EVs charging faster than ever, biblical-level AI revelations, Google splashing the cash, and even MI5 making a guest appearance (kind of). The crew breaks down what’s really happening in European tech and beyond.

💸 Markets Corner

  • Klarna Files for IPO – Targeting $15B valuation, down from $45B in 2021 but still a major move for European fintech.
  • CoreWeave’s Massive Leap – From $16M to $1.9B revenue in 2 years and acquiring Weights & Biases for $1.7B. IPO incoming.
  • Google x Wiz – Google’s record $23B acquisition of Israeli cybersecurity firm Wiz. Massive exit, but will the FTC let it slide?

⚡ EV Watch

  • BYD’s Battery Breakthrough – 5-minute charge for 470km? Game-changing for the industry. Tesla and Mercedes scrambling to keep up.
  • Tesla Recall Woes – Cybertrucks recalled due to panels potentially peeling off mid-highway. Not ideal.

🍽️ Food, Forever?

  • Bryan Johnson’s “Foodome” Vision – Sequencing the American diet like the human genome. Lofty or legit?
  • ZOE’s churn problem – Are personalized nutrition startups sticky enough?
  • UPF, Sugar Taxes, and Regulation – The gang debates whether real change comes from startups… or governments.

🧠 AI Corner

  • AI Jesus Speaks (a.k.a. Jensen Huang) – Nvidia’s GTC: new chips (Blackwell Ultra, Vera Rubin, Feynman) and bullish takes on reasoning + agentic AI.
  • Stargate vs. AIP – OpenAI’s mega-scale GPU buildout vs. Elon Musk’s counterplay with Microsoft, UAE, and BlackRock.
  • Europe Reacts – Macron’s €100B+ bet on sovereign AI and the case for Mistral leading Europe’s AI frontier.

🇪🇺 Europe in Focus

  • Data centers are consuming up to 30% of Ireland’s electricity
  • European VCs (hello Index Ventures 👋) are behind some of the biggest tech exits ever
  • Does Europe need its own AI stack? The guys debate strategic autonomy vs. commoditized smarts

🔐 Startup Espionage Files

  • Rippling vs. Deel, Flexport vs. FreightMate – Dirty tactics, source code theft, and lawsuits flying.
  • Dan's MI5 Story – An underground bunker, bugs from the CCP, and a face-to-face with British intelligence.
  • Lessons from the frontlines – Where does know-how end and IP theft begin? What happens when founders cross lines?

💤 Longevity, Sleep & 7PM Bryan

  • Bryan Johnson’s hyperbaric adventures, shocking news (literally), and… nighttime erections?
  • Why “7PM Bryan” is the biggest threat to longevity
  • Can Europe’s emerging “longevity clinic” wave go mainstream?

🎧 Memorable Quotes

“At some point, we’re going to wake up and realise the food system was as damaging as cigarettes.” – Lomax
 “We should invent our own future, not copy the US.” – Andrew J. Scott
 “20% of Ireland’s electricity goes to data centres — heading to 30%.” – Lomax
 “Only the paranoid survive.” – Dan
Upside #33 - UK DOGE, Project Europe, Trump's Real Tariff Tactics15 Mar 202500:42:18

The UK’s Cost-Cutting Drive – DOGE'esque?
UK government’s plan to cut civil service costs using AI-driven efficiencies. Public sector pensions estimated between £2.5-5 trillion – is cost-cutting enough? Will AI and startups play a role in optimising government spending?

Project Europe – Can It Keep Talent From Leaving?
20VC’s Harry Stebbings launches Project Europe to fund under-25s with €200K for startups. Inspired by the Peter Thiel Fellowship, but will it stop US firms poaching European talent? Lomax questions if we need more pre-seed funding or if growth capital is the real gap. Mads gives a history lesson on how Europe fell behind the US in venture capital.

AI Corner: Anthropic, Manus, & Google's Larry Page Returns
Anthropic scales annualised revenue from $1B to $1.4B in three months. Manus.im emerges as a powerful AI agentic platform (built on Claude 3.7). Larry Page launches Dynatomics, an AI startup focused on manufacturing. Microsoft explores alternatives to OpenAI, testing DeepSeek for Co-Pilot. Mistral shifts focus from LLMs to AI applications (finance, OCR, and tables).

The Market Meltdown – MAG7 Down $2.7 Trillion
Nvidia, Tesla, and others take a hit, erasing trillions in market value. Meta is the only MAG7 stock that didn’t drop. Could Trump’s tariff-driven trade wars be purposefully fuelling market volatility? Is this a short-term dip, or are we heading into a full-blown recession?

IPOs & M&A – Are We Finally Back?
63 IPOs in the US this year – up 90% from last year, but uncertainty looms. CoreWeave and Hinge Health file for IPOs, but timing may not be ideal. Figma, once blocked from an Adobe acquisition, now eyes public markets. The AI-powered startup Moveworks exits to ServiceNow for nearly $3B.

Deals of the Week
Lomax’s pick: Thorizon (Netherlands) raises €12M for next-gen nuclear reactors.
Dan’s pick: Stroll (France) raises €12M for AR-powered neurorehabilitation.
Digital therapeutics are making a comeback after a tough few years.

Upside Special - The Inside Track Of European Venture in 202525 May 202500:35:00

The real stories behind the headlines affecting European Venture.

This week Mads, Lomax, Andrew and I are all out and about at various conferences and events speaking with European LPs and GPs about our ecosystem - themes and trends for 2025 and beyond, how we grow, how we go toe-to-toe. The pitfalls, the breaks and beyond.

Interviews with:

Jone Vaituleviciute from First Pick
Francesco Perticarari from siliconroundabout.ventures
Charlotte Palmer from Integra Global Advisors
Mike Sigal from Sigal ventures
Dan Smith from Repeat Ventures
Antonio Miguel from Maze Impact
Ozge Oz from QNBEYOND Ventures
Philipp Herkelmann from EU Inc
Andreas Klinger from EU Inc and Prototype

Timestamps:

00:00 Introducing Dragons with Andrew Scott
07:40 Lomax goes toe-to-toe with Silicon Valley
13:05 Jone from First Pick and her Lithuanian adventures
15:15 Francesco from SiliconValley Ventures on 2025 deep tech opportunities
16:36 Oz from QNB and his one big ask
17:12 Charlotte from Integra - what to look for in emerging managers
19:50 Mike Sigal breaks down the European capital challenge
24:20 Dan from Repeat on renewed LP positivity
25:22 Antonio from Maze on Trump crushing Impact - or is he?
26:35 Mads with EU Inc founders Andreas and Philip - Why Europe why now

Upside Special - Poker Power For Founders & Investors17 May 202500:27:44

🎙️ Upside: Special Edition with Jo Living — Poker, Pressure & Performance in Business, Startups and Investing

Host: Dan Bowyer
Guest: Jo Living, Founder of ACES High

Jo Living joins Dan to explore the high-stakes parallels between poker and the business world. From her upbringing around cards to founding a FemTech startup and launching ACES High, Jo unpacks how poker has helped her navigate negotiations, raise capital, build teams—and teach others to perform under pressure.

01:07 – Jo’s Career Journey
From investment banking to FemTech founder to poker circuit regular, Jo traces the experiences that led to ACES High.

03:29 – The Trigger Moment
A trip to Morocco, winning a poker tournament while pregnant, and launching informal poker nights back home.

05:19 – Skills Poker Builds for Business
Jo outlines the key transferable skills: deep listening, risk management, performance under pressure, and reading the room.

05:59 – Poker & Gender Imbalance
Despite the male-dominated scene, Jo shares how the environment is evolving and why inclusivity—not 50/50 parity—is the goal.

07:44 – Lessons for Startup Teams
Jo compares limited data in poker and startups, bankroll/runway management, and the importance of making high-quality decisions consistently.

09:49 – Playing the Long Game
Resilience, persistence, and strategic decision-making.

10:29 – Aura Fertility & Negotiating as a Founder
Jo shares how she raised £600k for her FemTech startup and used poker instincts to navigate valuation and investor conversations.

13:55 – Negotiation Mistakes: The "All-In" Fallacy
Jo unpacks why some founders or investors go "all in"—and what they’re really signaling about negotiation ability and ego.

14:37 – Executive Presence & Investor Psychology
Playing not just the cards, but the perceptions. Jo explains how table presence mirrors founder confidence in boardrooms.

15:10 – Poker Misconceptions
Debunking myths: poker isn’t all bluffing. Jo explains the difference between bluff-based games and Texas Hold'em.

16:20 – Why Texas Hold’em is a Business Masterclass
Community cards mean shared data, emphasising logic, negotiation, and risk evaluation—not deception.

17:22 – Should All Founders Learn Poker?
Jo makes a strong case for poker as a self-awareness tool—revealing how we handle stress, risk, and conflict.

20:56 – Biggest Founder Lesson from Poker
Avoiding "tilt" after a setback and how to bounce back with focus and discipline.

21:45 – Bankroll Strategy & Knowing Your Levers
Jo explains why you need "enough chips to do damage"—and how that applies to leverage in business negotiation.

23:16 – Poker as a Hiring Tool?
Jo suggests poker simulations may outperform psychometric tests in surfacing resilience, strategy, and interpersonal savvy.

24:56 – Duplicate Bridge & Gamified Hiring
A thought-provoking take on creating controlled poker challenges to assess talent and founder potential.

26:07 – Poker is Not Just for the Bros
Jo highlights how beginner women often outperform overconfident players through disciplined, strategic play.

27:15 – Final Thoughts: A Tool for Strategic Insight
Poker as a lens for understanding investment decisions, founder mindset, and long-term success.

Upside #41 - Publics Meets Privates – What It Means for Venture10 May 202501:01:52

Upside: Public Meets Private – What It Means for Venture

In this episode of Upside, Dan is joined by Lomax from Outsized, Andrew from 7%, and Mads from SuperSeed to explore how public markets intersect with private markets—and why it matters for VCs and founders alike.

Key Topics Covered:

  • [00:01] Welcome & Intros:
    • Dan welcomes guests and sets the scene for a deep dive into public vs. private markets.
  • [02:00] Ørsted’s Offshore Wind Cancellation:
    • Mads unpacks the Hornsea phase four cancellation.
    • Energy security, interest rates, and the geopolitical chessboard.
  • [07:20] The UK’s Future of Compute:
    • Lomax highlights Albion VC’s report on UK deep tech and compute.
    • What went wrong with Graphcore and what’s next for quantum players like Riverlane and Quantum Motion.
  • [10:45] Healthcare IT & NHS Modernisation:
    • Andrew revisits the NHS’s tech failures and weighs the new £21B upgrade plan.
    • The case for agile, smaller tech firms in public procurement.
  • [16:30] DoorDash-Deliveroo Deal & EIF Market Pulse:
    • Dan covers DoorDash’s acquisition of Deliveroo and what it says about European tech exits.
    • EIF’s barometer survey: what’s top of mind for VCs and PE in Europe right now.
  • [18:38] UK-EU Youth Mobility & Trade Talks:
    • Mads outlines the potential for a youth mobility deal post-Brexit.
    • Lomax emphasizes the enduring importance of EU-UK trade vs. US-UK hype.
  • [20:55] Public Markets’ Role in VC:
    • Dan kicks off a new segment: why public markets matter even if you're a private investor.
    • Surprising stats on IPO sizes, US investor involvement, and cross-border exits.
  • [29:17] Lightspeed’s RIA Move Explained:
    • Lomax explains why Lightspeed and other big VCs are becoming RIAs.
    • What it means for fund structures, founders, and the evolving investment landscape.
  • [50:20] Secondaries Deep Dive:
    • The group discusses the booming role of secondaries in venture.
    • Liquidity, DPI, and how VCs are adapting to a world of longer-hold private assets.
  • [59:37] AI Corner:
    • Mads updates on Google’s new AI milestone overtaking Anthropic’s Claude 3.7.
    • OpenAI’s nonprofit drama and its funding round headaches.
  • [1:01:30] Deal of the Week:
    • Spotlight on two European drone unicorns: TechEver (Portugal) and Quantum Systems (Germany).
    • The rise of defence-tech in Europe and implications for global security.
  • [1:06:10] Marrakesh & EU VC Meetups:
    • Dragon Chasers VC retreat in Marrakesh—paragliding and power networking.
    • EU VC crew gathering in London to strengthen European venture ties.

If you're a founder, investor, or just passionate about startups and venture capital, Upside is your go-to source for deep dives into the trends shaping Europe’s tech scene.

Upside #40 - Pension Cash *Will* Unlock UK VC - But when, how & so what?03 May 202501:02:09

🎙️ Upside #40 Podcast — For The Real Stories Behind The European Venture Headlines

If you're into startups, VC investing, European Venture, or anything startup-ecosystem and business - this podcast is for you.

Host: Dan Bowyer (SuperSeed)
Guests: Lomax (Outsized), Mads (SuperSeed), Chris Elphick (BVCA)

00:00 — Introduction
Dan welcomes listeners to Upside, introducing co-hosts Lomax and Mads. Special guest Chris Elphick, Head of Venture Capital at the British Venture Capital Association (BVCA), joins to unpack the European venture scene.

🏛️ BVCA, Government, and the Venture Landscape

00:41 — Chris Elphick: Inside the BVCA
Chris shares BVCA’s role as the voice of UK VC, its upcoming conference, and engagement with government and industry leaders like Peter Kyle (UK Secretary of State for Science, Innovation and Technology).

01:30 — AI, MPs, and Government Tools
Discussion on the use of AI in government, freedom of information requests, and whether MPs should be criticised or encouraged for experimenting with tools like ChatGPT.

⚙️ Politics, Elections & Economic Backdrop

05:00 — UK Local Elections & Reform’s Rise
Chris and the team unpack local election results, the rise of Reform UK, and parallels with Trump-era political trends.

06:50 — US-China Trade War & Global Impact
Mads breaks down the effect of US-China tariffs on global trade, the likelihood of recession, and inflationary pressures.

✈️ Aerospace & European Tech Ecosystem

10:00 — Heart Aerospace Moves to the US
The team explores why Swedish startup Heart Aerospace is relocating to LA,  touching on the US-Europe funding gap and the challenges of raising large growth rounds in Europe.

13:00 — UK VC Fundraising Trends
Chris shares new BVCA data: venture fundraising doubled from £2.3B (2023) to £4B (2024), with notable increases in US LP participation, but highlights the persistent absence of UK pension capital.

💰 Pension Reform & the Scale-Up Gap

25:00 — EIS, VCT, & British Business Bank Programmes
Explaining the importance of Enterprise Investment Scheme (EIS), Venture Capital Trusts (VCT), and the British Business Bank in seeding UK funds.

35:00 — Mansion House Compact & Pensions
Deep dive into the push to unlock UK pension capital for VC:

  • Charge cap changes
  • LTAFs (Long-Term Asset Funds) are here
  • The Nova initiative (inspired by France’s Tibi scheme)
  • Challenges: fees, liquidity, education, performance

🌍 European Comparisons

56:00 — Who’s Doing Pension Release Well?
Discussion of successful pension-backed VC models in Sweden, the Netherlands, France (Tibi), and lessons for the UK.

🤖 AI Corner & Deal of the Week

58:00 — AI: Changing the Game
Mads highlights that ~30% of Microsoft and Google code is now AI-generated; Cursor hits 1B lines/day.

59:00 — Defence & Geopolitics
Lomax points to a Series A defence deal led by Index Ventures. Mads reviews the U.S.-Ukraine minerals deal as geopolitical chess.

Upside #39 - Lab Grown Meat Back On? Euro-Funds Swim In Cash & Why Anti-Trust Wins26 Apr 202500:31:55

🎙️ Upside Podcast: The Real Stories Behind The Headlines Affecting European Venture

Hosts: Dan Bowyer (SuperSeed), Andrew J Scott (7Percent), Mads Jensen (SuperSeed)

🔥 Episode Highlights

This week, Dan, Andrew, and Mads tackle the latest trends shaping Europe’s startup and tech ecosystem, including:

  • Cash Inflows into Europe:
    Massive cash movements into European funds – but how meaningful is this trend? Could instability in the US be Europe's gain?
  • Drone Regulations and the Future of Delivery:
    With new UK drone regulations expected by 2026, Andrew explores whether drone grocery delivery is realistic – and where it makes the most sense.
  • Wayve’s Breakthrough in Japan:
    Mads shares insights on Wayve’s strategic entry into Japan with Nissan, how it's setting a global stage for autonomous driving, and why Europe must compete.
  • Tesla’s Shifting Focus:
    Dan highlights Tesla’s Q1 struggles, Musk stepping back from DOGE, and what that could mean for Tesla’s full self-driving ambitions.
  • Early Stage VC Trends:
    Key findings from Dealroom’s Q1 report: healthtech dominance, foreign capital influx, and the evolving pre-seed landscape.
  • Is Europe’s Surge in Investment Patriotism or Pragmatism?
    The team debates whether Europe's increasing inflows are a flash in the pan or a sign of a long-term shift.

🥩 FoodTech & Future Farming

  • Lab-Grown Meat Breakthroughs:
    Exciting developments from the University of Tokyo, Meatly, Miriam Eats, and 3DBT are pushing lab-grown meat closer to supermarket shelves. The panel discusses why cost remains the main hurdle and why agriculture as we know it could radically change within 20–30 years.
  • Space-Grown Food:
    Space agencies are exploring cultivated food in low-gravity environments. Can startups tap into this cosmic opportunity?

🔍 OpenAI's Big Moves & Antitrust Drama

  • OpenAI Eyeing Google’s Chrome?
    The DOJ’s antitrust actions could force Google to sell Chrome – and OpenAI is reportedly interested. Is this good for competition, or are regulators overreaching?
  • The Future of Foundational Models:
    Should OpenAI stay focused on core models or build an AI-driven app store? The team unpacks what’s next for AI’s leading players.

🏥 Deal of the Week

  • Skin Analytics' £15M Raise:
    Dan spotlights Skin Analytics' Series B success to advance AI-driven skin cancer diagnostics — a meaningful healthtech leap for the UK.

🛠️ Policy & Regulation Corner

  • Deregulation Win:
    Mads celebrates new EU legislation easing sustainability reporting requirements — expected to save businesses €4–6 billion in administrative burden.

🌟 Bonus: Cool Startups & What's Next

  • Niobolt's Ultra-Fast Charging Tech:
    Andrew showcases a Cambridge spinout promising EV battery charging in under 6 minutes — a game-changer if it scales.

Thanks for listening to Upside – where we make sense of the chaos behind Europe's venture scene.


👉 Subscribe, rate, and share if you enjoy the show!


Upside #47 - Will AI Kill The Internet? IPO's Up? Can Doctors Beat AI?05 Jul 202501:05:32

🎙️ Upside #EP— IPOs, AI vs Doctors, London’s Trouble & The Internet’s Future

⏱️ 02:30 – Figma’s IPO & European Stakes

  • Filing in NYC after failed Adobe acquisition
  • $800M+ revenue, 91% margins, 132% NDR
  • $5B Index Ventures payday
  • Why this matters for Euro tech

⏱️ 08:50 – London’s IPO Disaster

  • Worst first half in nearly 30 years: only $160M raised
  • AstraZeneca flirting with a US listing
  • Can London come back?
  • 25+ years of decline traced to pension reform post-Maxwell scandal

⏱️ 14:10 – UK vs US Markets: Staggering Comparison

  • US market cap: $60T vs UK: $3T
  • Tech in FTSE 100: only 1%
  • Apple alone = FTSE 100
  • Institutional apathy + structural rot

⏱️ 18:00 – Pension Power & Mansion House Debate

  • UK pension funds hold just 5% in UK equities
  • £40B in annual tax breaks not translating into local investment
  • Need for regulatory overhaul to unlock capital

⏱️ 22:00 – Fixing the Public Markets

  • Public markets *should* be the exit path
  • Without them, the entire private capital waterfall stalls
  • Stagnation in public exits affects tax receipts, job creation, and the UK ecosystem

⏱️ 25:45 – European Equities Surge

  • Biggest outperformance vs US stocks on record
  • €46B inflows in 2025 vs €66B outflows in 2024
  • Germany wakes up: €500B in infrastructure & defence spend
  • Sustainable or a short-term Trump-driven rotation?

⏱️ 32:00 – UK Budget Black Hole

  • £5B budget gap after Labour’s U-turn
  • Highest tax burden since WWII
  • Social care + NHS = nearly 50% of budget
  • Stuck between tax pledges, borrowing risks, and spending pressures

⏱️ 41:00 – UK Future - 3-Paths

  • Stasis: stealth taxes, zero reforms
  • Further decline: shrinking influence
  • Recovery: bold reforms in pensions, NHS tech, and civil service productivity
  • What road will we take?

⏱️ 46:30 – EU AI Act: Incoming Train Wreck?

  • Set for August rollout, but 44 major firms ask for pause
  • Missed code-of-practice deadline - What do we do?
  • Healthcare, finance, and SaaS startups at risk
  • GDPR 2.0 on steroids?

⏱️ 52:45 – Can We Save the Open Web?

  • Cloudflare’s bold move to gate AI scraping
  • API-first monetisation and licensing models emerging

⏱️ 57:45 – AI vs Doctors

  • Microsoft benchmark: AI got 80% of diagnoses right vs doctors’ 20%
  • The end for doctors?
  • Regulation, infrastructure, and explainability still big hurdles

⏱️ 01:05:00 – Deal of the Week: Portal Biotech

  • $35M Series A led by Earlybird + NATO Innovation Fund
  • Protein sequencing tech spun out of University of Groningen
  • Hopes to be “the Illumina of proteins”
  • A deeptech win for Europe
Upside #46 - Is Big Tech Britain On Track? Bubble or Boom?28 Jun 202500:53:12

🎙️ Episode Highlights

00:00 – Market Pulse: We’re So Back Baby!
US IPOs are red-hot (CoreWeave, Circle), S&P nearly at ATH, and Q2 GDP forecasts hit 3.5%.
The resurgence in AI and crypto-led optimism despite fiscal clouds.

03:00 – Bubble or Boom?
Are we heading into bubble territory?
US deficits are ballooning, but M&A tailwinds and LP liquidity look promising.

05:00 – The Sentiment Effect
Economic psychology: consumer sentiment drives GDP.
Europe’s problem? It talks itself down. The US? Belief + boldness.

06:50 – Big Tech Bets on Britain
Amazon pledges £40B UK investment (data centres, fulfilment, even a film studio).
British Business Bank expands to £25B. Visma chooses London IPO over Nasdaq—confidence win?

14:00 – UK’s 10-Year Industrial Push
Gov’t targets AI, defence, creative, and energy—aiming to slash grid connection delays.
Electricity costs still a major drag. Can policy execution catch up to rhetoric?

18:00 – The UK’s Economic Reality Check
High inflation + stagnant growth = stagflation-lite.
£66B in working-age benefits forecast by 2029. Labour’s internal revolt blocks real reform.

27:00 – Tariff Tensions Mount
Trump trade wars return: EU braces for July 9 deadline. Retaliation looms.
Could German auto exports be the pressure point?

32:00 – AI in the Wild
Apple eyes Perplexity. DocuSign sues scrappy 2-day clone.
Seed-strapped startups exit for millions without VC - Paradigm shift or PR hype?

37:00 – Copyright Battles Begin
Meta & Anthropic win round one using “transformative use” defence.
The big legal fight (OpenAI vs NYT) still looms.

41:00 – Robotaxi Rollout?
Tesla demos driverless fleet in Austin - damp squib? Still lagging Waymo.
Real progress or just share-price theatre?

43:00 – Europe’s Bay Area Dream
Can Europe become Silicon Valley? Should we can we?
It’s not about funding - it’s confidence, imagination, and embracing failure.

51:00 – Optimism Please!
Q2 earnings optimism and promising chip efficiency breakthroughs.
Markets strong, founders bold, and Europe's moment (maybe) coming.

Upside #45 - Proxy Wars, Booming IPOs, & Defence Saves Europe21 Jun 202500:53:45

🎙️ Upside 45 Podcast – “Defence, Dirty Deals, and Disruption”

This week 

  • EU defence spend motors - will it save us?
  • European Space Agency military satellites 
  • US-China competition - European opportunity?
  • US IPOs up 30% this year, so far, so what
  • British surgical robotics start-up -> sell-out

⏱️ [01:13] – Geopolitical Hotspots and Defence

  • Iran’s global influence and diaspora
  • Ukraine’s resistance to Israel-Iran dynamics
  • Cautious optimism about regime change 
  • WWIII has begun?

⏱️ [03:35] – Oil & Markets

  •  Brent crude spikes (from $70 → $77, possibly $100+)
  •  Shipping, inflation, and interest rates affected
  •  Bank of England holds rates amid uncertainty

⏱️ [05:52] – Impact on Venture?

  • Founders not immediately impacted, but long-term capital flow risks flagged
  • Defence tension might dry up funding or shift VC attention

⏱️ [06:56] – Defence as a European Economic Engine?

  • Defence our financial lifeline? But VC exposure to defence is tiny

⏱️ [09:35] – Unicorns in EU Defense Tech

  • 3 recent unicorns: Helsing, Tekever, Quantum Systems
  • Helsing shifts gear
  • VCs rush in - BUT Sales cycles, procurement, regulation

⏱️ [12:38] – Helsing’s Capital & The VC Taboo 

  • US firms: Lightspeed, Accel, General Catalyst 
  • Homegrown capital is crucial to reducing 10x funding gap with US
  • EIF restricts arms/weapons investments
  • Helsing’s value as a “reference company” for LPs

⏱️ [18:51] – ESA’s Satellite Plans

  • EU Space Agency wants €1B+ to build military satellite network.

⏱️ [22:15] – Iris vs Starlink Context

  • Iris <> Starlink
  • EU must move fast on sovereignty or risk dependence

⏱️ [23:59] – NASA Cuts vs ESA Budgets

  • NASA’s proposed 25% cut
  • Europe’s ESA increasing funding—ironically divergent paths

⏱️ [25:52] – China, Trade Wars, and Supply Chains

  • EU’s dependence on Chinese imports (clean tech, chemicals) 
  • Fear of trade dumping post US-China de-coupling 
  • Rare earth constraints impacting defence and auto industries

⏱️ [29:45] – Tariff Timelines

  • July 9 tariff decision
  • Potential EU-US mini deal to avoid Trump’s punitive tariffs
  • Pharmaceuticals next

⏱️ [32:00] – IPO Boom in the US 

  • Chime, Circle, CoreWeave IPOs—massive post-IPO pops 
  • Klarna leads EU pipeline

⏱️ [34:04] – IPO vs Private Capital

  • Bill Gurley’s hatred of bankers
  • Private markets still offering better valuations
  • SPACs are back!

⏱️ [36:25] – Surgical Robots and CMR Surgical

  • CMR (Cambridge Medical Robotics)
  • Raised $1B, now eyeing $4B exit
  • Premature exit
  • CMR’s potential lost
  • Scale homegrown tech more aggressively

⏱️ [44:45] – Deed of the Week

  • Daniel Ek’s €600M into Helsing
  • Paris-based Nabla raises $70M Series C
  • Scale AI deal closes in one week
  • Fastest capital deployment of its kind; no FTC review needed

⏱️ [49:05] – Founders in Government

  • Alex Depledge named UK entrepreneurship advisor
  • Praise for founders like Matt Clifford shaping UK tech policy

⏱️ [51:10] – Meta’s AI Talent War

  • Meta’s aggressive poaching of OpenAI talent
  • AI job market likened to football transfer season
  • Pay off or backfire?
Upside #44 - Cybercrime Up, UK Govt Investments Up, Nuclear Up, War... Down.14 Jun 202500:56:10

Upside - The *real* stories affecting European Venture.

This week Mads, Lomax and I discuss: AI cybercrime, UK govt investing in tech/AI, cheap energy (nuclear isn't), Tesla’s RoboFail, 996 and founder work-life balance, AI growth but is the revenue good? and the shock flip between private vs. public markets.

  • 01:24 – Cyber-Security: Rising Threats
    43 % of UK businesses hit by cyber-crime last year; avg. of 2,000 attacks/week in Q1 2025. 
  • 02:07 – AI-Enabled Attacks & Geopolitical Impact
    AI tools lower the barrier for sophisticated attacks by state-sponsored or rogue actors - new front in modern warfare by economic disruption.
  • 04:12 – Kinetic vs. Cyber Warfare
    The mix of traditional (kinetic) and cyber fronts.
  • 07:20 – Government Spending Review: Big Picture
    Rachel Reeves’s 3-year spending framework amid a weak UK economy: £120bn on infrastructure; £43bn for science & innovation; £2bn AI Action Plan.
  • 16:50 – Energy Landscape & Nuclear
    The UK’s high industrial energy costs (6× US); sovereignty & intermittency issues; nuclear offers clean baseload and sovereignty but at what cost?
  • 19:21 – Fusion & Long-Term Energy Tech
    Recent fusion advances (Tokamak West’s 22 min plasma) and Proxima Fusion’s €130 m Series A, but 20 yr horizon remains.
  • 25:51 – Tesla’s Robotaxi Roll-Out
    Tesla’s delayed Austin launch (moved from June 12→22); cost comparison vs. Waymo.
  • 28:34 – Europe’s AV Landscape: The Brexit Dividend
    Wayve’s UK partnerships (Nissan, Uber, spring 2026 trial at L4 autonomy) versus EU’s slower L2/3 regs.
  • 32:26 – Founder Work Ethic Debate
    Heated talk around “996” & extreme hustle: Lomax quotes Paul Graham on youth vs. age advantages.
  • 37:00 – AI Revenue Growth & Sustainability
    LLM businesses doubling revenue every 2 months; examples: Anysphere’s $500m ARR, Lovable’s €61m ARR; concerns around gross margins, churn & long-term profitability.
  • 46:14 – Private vs. Public Market Performance
    First time in 25 yrs that private markets underperform public across 1/3/5/10 yr horizons (State Street report): “Magnificent 7” driving public returns. A shake-out & opportunity ahead as private seeks its illiquidity premium.
  • 52:00 – Notable Deals
    • Multiverse (ES) – €189m Series B for LLM compression tech (95 % size reduction)
    • Oxford Ionics → IonQ – $1bn+ acquisition of UK trapped-ion quantum spin-out
  • 55:47 – Closing & Condolences
    Dan sends thoughts to those affected by the Air India crash, and wraps up with thanks and next-week teasers.
Upside #43 - EU Rate Advantage, Naughty Lawyers, AI Copy…right? A UK Defence Reviewer Says What? 07 Jun 202500:49:48

Hosts: Dan Bowyer, Lomax Ward, Mads Jensen.

The real news behind the headlines affecting European Venture.

ECB interest rate cuts, IPO market divergence, AI copyright tension, UK Strategic Defence Review, and the NHS starts liquid biopsies.

00:58 – ECB Rate Cuts: So what for Europe and Startups?
8 rate cuts in 12 months signals easing. EU’s sub-2% inflation vs. US’s higher inflation + deficit (~7% of GDP).Fiscal strength = leverage for defence and energy investment.

04:34 – Capital Flows & Sentiment
Will a weaker euro drive more capital to riskier assets?

05:27 – Contrasting the US Volatility vs. EU Stability
Volatility in the US makes EU relatively attractive, but low EU growth remains a concern. Lower rates long-term can push capital into startups and infrastructure.

07:21 – IPO Markets: A Tale of Two Cities
US IPO market is booming (+80%), UK (-80%). 143 US IPOs vs. 5 UK IPOs YTD. $13B raised in US vs. ummm £75M in UK?!

09:11 – Why is the UK IPO Scene Lagging?
US market cap ~17x that of UK; daily trading 50x more.

12:35 – Pisces Liquidity Schemes: Public vs. Private Market Debate
Pisces—a new semi-liquid scheme for startup equity. Private markets aren’t built for public-style trading. Carta tried—failed.

15:11 – Systemic Decline of London’s Public Market
From ~1/3 the size of S&P 500 in 2007 to 1/17 today. Staggering numbers.

21:49 – UK Defence Review: Investment & Opportunity
New £87B plan over 10 years. Will it benefit startups? Still heavily physical (~80%), but £400M earmarked for innovation.

28:24 – Sovereign Tech & Europe's Defence Role
Is £400M enough? Contextualised vs. Anduril’s $2.5B raise.

37:08 – AI Infrastructure in Europe
Links defence with economic growth. EU's €20B AI Superfactory plans underway; Germany’s first data cluster. Huge challenge: power costs & permitting.

40:19 – NHS Liquid Biopsies: Tech Meets Real-World Healthcare
NHS rolling out liquid biopsy for lung/breast cancer patients. Huge potential.

45:54 – The Case for Healthcare Tech Efficiency
NHS productivity is down despite 14% spending increase since 2019.

46:12 – Deals of the Week
MUBI: UK-based streaming platform raises $100M from Sequoia.
Beckley Psytech & Atai merger: A pivotal moment for psychedelics + mental health.
Grammarly: $1B non-dilutive raise led by General Catalyst; Ukrainian roots, US-led round.

Until next week fine people...

Upside #42 - Worlds Biggest Trade + EU Scale-err-up Strategy + The Jony & Sam Love-in31 May 202500:45:21

Trade Wars, Tariffs, and Tech Shifts – The Big Picture Shaping European Startups

With Dan Bowyer, Mads Jensen & Lomax Ward

00:00 – Intro: The Need to Talk Tariffs

  • Dan kicks off the episode with a reminder: No groans, we need to talk tariffs.
  • Taco tariffs, international trade deals, and looming US-EU trade tensions.

00:29 – Federal Judges, EU-US Trade, and Startup Impacts

  • The EU-US trade deal cajoled activity: what does it mean for investors, startups, and Europe?

00:59 – Lomax’s Context: The Behemoth US-EU Trade Relationship

  • $1.5 trillion annual trade; US-EU dwarfs US-China.
  • Why has there never been a formal trade deal? Regulatory misalignments and subsidy wars (Airbus-Boeing).
  • Harmonisation of standards as a critical issue—hardware startups especially at risk.

02:12 – Regulatory Divergence and Why It Matters

  • EU’s precautionary principle vs. US’s risk-based model.
  • Trade deals aren't just tariffs—harmonising standards can unlock growth.

03:50 – Hardware Startups & the Tariff Threat

  • 10% of EU startups are hardware—“they will struggle if tariffs hit 50%.”

04:28 – The China & Russia Factor in Trade Rebalancing

  • Trump’s chaotic policies, stock markets up despite tariff shocks.

06:01 – Inflation, Deficits, and Market Volatility

  • Residual tariffs could push US inflation by .5-1%.
  • “Congress looking to add $3-4 trillion over 10 years.”
  • The importance of EU sophistication in trade negotiations

08:55 – Direct vs. Indirect Impact on Startups

  • Tariffs affect hardware directly; inflation and interest rates indirectly.
  • Interest rates impact M&A, liquidity, DPI, and venture capital flows.

11:27 – Markets’ Schism: Bond Traders vs. Equity Investors

  • Bond traders panic over risk; equity investors bet on AI’s promise.

12:09 – Trump’s Amplifier Effect: Deregulation vs. Chaos

  • The paradox of Trump’s anti-regulation stance fuelling optimism vs. destabilisation.

13:42 – EU’s Startup & Scale-Up Strategy: Will It Work?

  • €10B blended fund, blue carpet initiative for talent, regulatory simplification.

17:23 – The Slow Pace of EU Policy: 2026-27 Timelines

  • Lomax: “28th regime sounds like a Robert Harris novel—big thanks to Andreas Klinger for pushing it.”

19:50 – Employee Stock Options: Europe’s Broken System

  • The need for harmonisation—“It’s key to unlocking talent.”

21:49 – Big Tech Announcements: AI’s Velocity

  • Google I/O, Microsoft Build, Nvidia’s blowout quarter.
  • AI’s exponential growth—“50x increase in token processing in a year.”

27:30 – The Application Layer: Opportunities and Disruptions

  • AI’s impact on startup building: velocity of product cycles, risk of obsolescence.
  • Dan: “Will SaaS die as AI tools empower in-house builds?”

36:54 – OpenAI + Johnny Ive: Hardware, Form Factors, and Speculation

  • A $6.5B stock deal, secretive hardware project—pendant? Phone? Glasses? A new paradigm?
  • “I hope it’s not a pendant!”

39:10 – The Race for the Next Form Factor

  • Apple’s stagnation; OpenAI’s ambition to dethrone them.

41:10 – Wrap-Up: EU Urgency, Munich’s Tech Momentum, and the Week Ahead

  • Munich as a growing hub: TSMC, Apple, Quantum Systems.
  • Lomax: “Bright Flag’s $425M exit is a big deal for the European ecosystem.”
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