Explore every episode of the podcast Truncated Thoughts

In this episode, Maikel and Jeremy discuss ChatGPT in terms of how it and other NLP models are playing a role in healthcare. A few areas mentioned include diagnostics, image reading, patient advice, and subsequent innovative applications for data synthesizing.

Any comments or questions can be shared directly to Jeremy at  jschmerer@prescouter.com

The podcast returns! In this episode , Jeremy and Kelsey dive into a discussion about the Olfactory system to breakdown a series of topics related to our sense of smell.  Topics covered include taste vs. smell, loss of smell, neuroscience behind experiencing scents, neurodegenerative diseases and whether robots coud learn to smell! Enjoy!

Any comments or questions can be shared directly to Jeremy at  jschmerer@prescouter.com

Jeremy , Joao, Maikel, and Ryan discuss Monkey Pox in terms of its origin, spread, treatment, vaccines, MRNA, public health perspective, and more.

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com. 

In this episode, Jeremy takes a step back from the normal cadence of the podcast to explain in simple terms who PreScouter is and the kind of work they perform.

For those interested in learning more please contact Jeremy directly at jschmerer@prescouter.com

Jeremy and Maikel discuss the Covid-19 pandemic in terms of where we are now and some of the new questions being asked as things continue to evolve.  Some of the pros and cons of available treatment options are also discussed. 

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

In this episode, Jeremy, Maikel, and Ryan discuss the large and exponentially growing world of data in the context of pharmaceuticals. Some areas touched upon include data connections, structured vs. unstructured data, negative clinical trials data, data sources, EMR, using AI + NLP tools, regulatory pace, data standards, and more! 

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

In this episode, Jeremy, Ryan,  Maikel, and Joao discuss augmented reality and how it is being used in surgical settings. Areas touched upon include: expedited surgical training, physician shortages, AR challenges / design,  collaborative surgeries, haptic feedback, outcomes, quality assurance, and AR implementation.

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

In this episode, Jeremy, Ryan, and Maikel discuss organ transplants in terms of the biological and cellular processes at play before, during, and after a transplant occurs as well as innovations in the field.

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

In this episode, Jeremy, Ryan, and Maikel discuss the age old concept of the "Internet of Things" as it relates to the healthcare world. With a growing opportunity for medical devices to speak to each other and transmit data, there were no shortage of directions to go in for this episode. We hope you enjoy.

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

Historically, it takes 10 years and a billion dollars to develop a drug. In this episode, Jeremy and Ryan unpack how this may be changing both as a result of innovation as well as recent necessity. 

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

The Covid-19 virus continues to evolve with more and more people contracting the virus for the first or even second time. As such, there are still lots of questions pertaining the recent Omicron variant, testing protocols, and infection / risk scenarios. In this first episode of 2022, Jeremy and Maikel attempt to answer some of these questions.

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

In the final episode of 2021, Jeremy is joined by technical colleagues: Ryan, Maikel and Joao to unpack the pandemic thus far. This "round table" discussion highlights key innovations born out of necessity, proactivity, and also as a result of evolving cultural shifts. Jeremy also asks the team to make predictions regarding the future of the pandemic.

Questions, feedback, or suggested topics for future episodes can be directed to jschmerer@prescouter.com.

Jeremy, Ryan, and Maikel discuss patient data manangement in terms of collection methods, data integrity, data filters, and advanced algorithms for the actionability of different data points. Future implications of relationships between doctor, patient, and data colletion systems are also discussed.

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

Jeremy and Ryan discuss CRISPR in the context of diagnostics.  One interesting postulation  was the notion that CRISPR could be used proactively for variants of infectious diseases that don't quite exist yet. Another is how it could be used for Personalized Vaccination

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

Jeremy, Ryan, and Maikel discuss Process Analytical Technologies (PATs) in the context of pharmaceutical manufacturing. Some areas discussed include cost, quality controls, cell line development, automated sampling,  predictive modeling, bioreactors, and various measurement tools.

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

Jeremy, Maikel, and Ryan discuss epigenetics in terms the occurrence of DNA changes, why they matter, their complexity, and how they impact treatments and diagnosis of certain diseases.

You can submit questions, feedback, or suggest topics for future episodes directly to jschmerer@prescouter.com.

Jeremy, Ryan, and Maikel compare and contrast the dynamics of Covid-19 immunity, which comes from both contracting (and overcoming) the virus itself and from the available vaccines. Regardless of your views on vaccines and the pandemic in general, this is an insightful discussion intended to make sense of an unfortunately inescapble topic.

You can submit questions, feedback, or suggested topics for future episodes directly to jschmerer@prescouter.com.

Jeremy, Ryan, and Maikel discuss the good and perhaps the not so good as it relates to early diagnostics for various diseases. Some of the topics examined include: false positives, ultrasensitive immunoassays, dangers in comparing to averages, cost benefit analysis of testing, at home testing, molecular fluctuation, PCR tests, and liquid biopsies. 

You can submit questions, feedback, or suggested topics for future episodes directly to jschmerer@prescouter.com.  

Jeremy and Ryan discuss telemedicine from several perspectives including connectivity, how healthcare providers use it to work with one another, the advent of "uber for doctors," regulatory / logistical concerns, and general innovation. 

You can submit questions, feedback, or suggested topics for future episodes directly to jschmerer@prescouter.com.  

In this episode, Ryan and Jeremy discuss proteomics in terms of why it's relevant and what are some of the innovations in the field.

You can submit questions, feedback, or suggested topics for future episodes directly to jschmerer@prescouter.com. 

Joao, Maikel,  and Jeremy have a conversation about booster shots, which has certainly been a hot topic as the world continues battling the Covid-19 pandemic. What is the effectivness of a booster? How long will it last? Does it account for variants? Would a booster shot end the pandemic?

You can submit questions, feedback, or suggested topics for future episodes directly to jschmerer@prescouter.com. 

Ryan and Jeremy have a conversation about academic research particularly in the biomedical space. There is an immense amount of information available in public domains. How does it get there? How credible is it?

The conversation goes in many directions such as experiment design, data, funding, peer-review processes, tenure,  and more.

You can submit questions, feedback, or suggested topics for future episodes directly to jschmerer@prescouter.com

Jeremy and Maikel have a conversation about bacteria. Some topics discussed include tuberculosis. antibiotic  resistance and misuage, Covid-19, diagnostic innovations, and the concept that most bacteria isn't harmful.

Questions, comments, or topic requests can be submitted to jschmerer@prescouter.com

Jeremy and Ryan discuss benign tumors and dig into imaging techniques, biopsies, mutations, tumor shapes, and more. 

Questions and comments can be sent to jschmerer@prescouter.com.

Jeremy and Ryan discuss nutritional supplements, which is a massive space given society's focus on healthy lifestyles and eating. Differences in regulations between supplements and pharmaceuticals are discussed as well as elements of personalized nutrition.

Ryan also comments on the potential use of A.I. in the nutrition world, because sometimes he just can't help himself.

Questions and comments can be sent directly to jschmerer@prescouter.com

Jeremy and Ryan have a "heart to heart" in their discussion of aortic stenosis. The conversation goes in a few directions including genetics, diagnostics, innovative treatments, catheters, and comparisions to other organs.

Questions and comments can be directed to jschmerer@prescouter.com

Jeremy, Ryan, and Maikel put their heads together to discuss infectious disease in terms of origins, detection, diagnostics, and containment. This conversation is particularly insightful as it touches on the economic implications at work in outbreak responses.

1. Disease Reservoirs
2. Covid-19 Perspective
3. Antibiotic Resistance
4. Public Health 
5. Ebola
6. "Evolved" diseases such as HIV
7. PCR Tests

Questions, comments, and suggested topics can be submitted directly to Jeremy at  jschmerer@prescouter.com

Dr. Joao Guerreiro rejoins Jeremy and Ryan for a conversation about clinical trials. The conversation goes in several directions as there is a lot to cover in this space. A few of those areas are listed below:

1. Patient Selection
2. Site Selection
3. Administrative Bottlenecks
4. Recruitment
5. Technology adoption
6. Safety and Efficacy 
7. Data Analysis
8. Trial Design

Comments, questions, and suggested topics for future episodes are welcomed and can be directed to jschmerer@prescouter.com.

In this episode Jeremy and Ryan discuss synethic biology. Key topics include:

Molecular Pathways
Manufacturing
Proteins
Drug Harvesting
Scalable Bioreactors 
Biosimilars
Car-T Cells
Animal Testing

We welcome your comments or questions at jschmerer@prescouter.com   

In this episode, Jeremy, Ryan, and guest Maikel Boot discuss long read DNA sequencing and its role in making it easier to look at DNA. A few areas addressed during the discussion include:

1. Oncology
2. Liquid biopsies
3. Rare variants
4. Reassembling DNA
5. Base pairs
6. Diagnostics 

Submit your comments or suggested topics to jschmerer@prescouter.com

In this episode Ryan and Jeremy are joined by materials scientist, Christian Salles, where sustainability is discussed both in relation to life science industries as well as at the macro level.  Some topics discussed include:

- Single Use Products
- Bi-Products
- Vaccine Production
- Recyling Processes
- Sustainability Metrics
- Green/Ethical Investing
- Corporate Sustainability Strategy

For questions, comments, and inquiries please submit to jschmerer@prescouter.com

In this episode Jeremy and Ryan discuss autoimmune diseases in terms of the challenges with developing treatment plans. Some key topics discussed include:

Drug Development
Personlized Medicine
Inflammation
Recognition of Self
Stress
Immune Suppression 
TGF Beta

We welcome your comments or questions at jschmerer@prescouter.com   

Jeremy and Ryan discuss brain computer interfaces in terms of how this technology works and what role it can play in restoring motor function for those with neurological disorders.

We welcome your comments or questions at jschmerer@prescouter.com   

In this episode, Jeremy, Ryan, and Joao discuss nanotechnology in terms of its applications in areas like drug delivery, diagnostics, surfaces, and more. Potential challenges associated with the use of nanotechnology are also discussed.  

Given our time constrained format, we would like to acknowledge that we have only scratched the surface of possibilities in this space and can be reached at jschmerer@prescouter.com if you have questions or comments regarding the content of this episode.

In this episode Ryan and Jeremy discuss the idea of Labs on a Chip, which allow for better screening and discovery work. One example involves the ability to simulate potential drug development failures early in the process before they become extremely expensive to the drugmaker.  Other subjects addressed include:

Cardio Toxicity
Biomarkers
Chemotherapeutics 
Animal Models
Testing Cost and Scalability 

In this episode, Jeremy and Ryan are joined by team member, Joao Guerreiro, to discuss mRNA and its possibilities outside of the recent success in the Covid-19 vaccines.  Some possibilities touched upon include using mRNA to create vaccine therapies for diseases such as Cancer and Alzheimers.

Given our time constrained format, we would like to acknowledge that we have only scratched the surface of possibilities in this space and can be reached at jschmerer@prescouter.com if you have questions or comments regarding the content of this episode.

Jeremy and Ryan discuss the function of bioreactors in the development of pharmaceuticals and vaccines. 

Jeremy and Ryan also would like to know what YOU would like us to discuss next. You can reach Jeremy directly at jschmerer@prescouter.com to suggest our next discussion topic within the life science arena.

Jeremy and Ryan have a conversation about advancements, procedures, and perspectives in the cardiology space. 

Jeremy and Ryan also would like to know what YOU would like us to discuss next. You can reach Jeremy directly at jschmerer@prescouter.com to suggest our next discussion topic within the life science arena.

Jeremy and Ryan speak about regenerative medicine. Topics include:

Car T Cells
Pluripotent stem cells
Scalability
Universal Donor Cells
Transplants 
Scaffold Proteins
Off-Target Cell Differentiation

If you have further questions, please reach us at jschmerer@prescouter.com

Jeremy and Ryan discuss 3D printing from many perspectives including :

1. 3D printed drugs and its personlization capabilities as well as logistical efficiencies 
2. Applications in surgical contexts
3. Prosthesis granularity
4. Future innovation
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan discuss drug delivery systems in terms of current functionalities as well as novel delivery systems under development.
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan dive into stem cell functionality, therapies, and challenges.
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan engage in a discussion around battery technologies with the help of special guest, Dr. Sofiane Boukhalfa, a materials scientist. 
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan continue their discussion around Robotic Surgery with an increased focus on 5G, latencies,  materials, programming, and more.
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan discuss applications of robotics in surgery and other medical procedures.
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan discuss over the counter drugs in terms of safety, the pandemic, savvy consumers, and opportunities.
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan continue their conversation on Artificial Intelligence with a focus on drug discovery. 
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan start a conversation on Artificial Intelligence. With a multitude of directions to go in for this topic, the episode touches on A.I. in terms of diagnostics, hospital operations, and clinical decision support.
 
We welcome your questions or comments on this subject or others. To contact us, you may email Jeremy directly at jschmerer@prescouter.com.

Jeremy and Ryan discuss generic and biosimilar drugs in the context of what they are, how they come to exist, patents, and future opportunities.

We welcome your questions or comments on this subject or others. To contact us you may email Jeremy directly at jschmerer@prescouter.com.

In this episode Jeremy and Ryan delve into the world of CRISPR. It is truly a massive space, but how it works along with some of its advantages and disadvantages are discussed. Enjoy. 

We welcome your questions or comments on this subject or others. To contact us you may email Jeremy directly at jschmerer@prescouter.com.