Explore every episode of the podcast This Week in Virology
Dive into the complete episode list for This Week in Virology. Each episode is cataloged with detailed descriptions, making it easy to find and explore specific topics. Keep track of all episodes from your favorite podcast and never miss a moment of insightful content.
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Title
Pub. Date
Duration
TWiV 1353: Phage bet-hedging and EBV antibodies
30 Aug 2026
01:52:01
TWiV explores how bacteriophages enable bet-hedge against bacterial immune defenses, and how transgenic mice engineered to produce human antibodies yielded potent anti-EBV candidates targeting gp350 and gp42, a promising step toward Epstein-Barr therapeutics.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1352: Clinical update with Dr. Daniel Griffin
29 Aug 2026
00:48:56
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are disheartened by the suggested change in federal vaccine recommendations, how Florida rolled back 4 childhood vaccine school requirements, results from a clinical trial suggesting that IPV can be used for outbreak control in IPV only countries, the continued national cyclosporiasis and screwworm outbreaks, size of the Ebola outbreak in the Congo, the death of 2 children in Pennsylvania from measles and the economic cost of the measles outbreak before Dr. Griffin deep dives into the use of monoclonal antibodies and remdesivir to treat Bundibugyo virus infection, measles outbreak, recent statistics RSV, influenza, SARS-CoV-2 infections, access and how pay for Paxlovid, , where to go for answers about long COVID-19, clinical guidelines for treating long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.
Effect of inactivated poliovirus vaccine on nasal mucosal immunity and pharyngeal shedding following novel oral poliovirus vaccine type 2 challenge: A randomized, open-label trial (JID)
Cardiac outcomes following SARS-CoV-2 infection versus BNT162b2 vaccination in adolescents and young adults: a cohort study of 4 million individuals (Vaccine)
mRNA COVID vaccine linked to lower risk of myocarditis in teens, youngadults (CIDRAP)
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1350: Clinical update with Dr. Daniel Griffin
22 Aug 2026
01:00:49
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are perplexed by the state of global public health as malaria, cholera and other infectious diseases are spread by civil warfare, the lack of manpower at the CDC to implement Congressional health programs, the first cancer mRNA vaccine resulting from a Merck and Moderna collaboration, how cyclosporiasis and screwworm outbreaks continue, FDA approval of new drugs against screwworm and critical policy decisions to control the Ebola outbreak in the Congo, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza, SARS-CoV-2 infections and the drop in vaccination rates in the US, how schools are the source of measles infection, how vaccines only prevent severe disease not transmission as trafficking of measles on vaccinated people begins to be acknowledged, to access and pay for Paxlovid, what to know about the mRNA flu vaccine, where to go for answers about long COVID-19, clinical guidelines for treating long COVID, three myths of respiratory disease and contacting your federal government representative to stop the assault on science and biomedical research.
Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis (LANCET)
A national programme of bivalent prefusion F vaccination in pregnancy and protection against respiratory syncytial virus hospitalisation in infants until age 6 months in the UK: a multicentre, prospective, test-negative, case–control study (LANCET)
Real-world studies show RSV immunizations protect newborns in their first year of life (CIDRAP)
Waste water scan for 11 pathogens (WastewaterSCan)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1349: Smallpox and mummies
16 Aug 2026
02:02:43
TWiV explains how liquid–liquid phase separation and a phage-encoded inhibitor cooperatively drive transcriptional transition during phage SPO1 infection, and the first smallpox virus genomes from an early outbreak in South America.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1348: Clinical update with Dr. Daniel Griffin
15 Aug 2026
00:54:40
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are troubled by the latest executive order changing routine childhood vaccine recommendations, the call for nominations to join the Advisory Committee for Immunization Practices, West Nile virus transmission in South Carolina, a newly identified midge-transmitted virus sickening cattle, and development of a cold-chain free DPT vaccine, the national cyclospora and screwworm outbreaks,new screwworm and genomics of Ebola outbreak in the Congo, and use of a mismatch vaccine to combat the Bundibugyo virus outbreak before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, where to go for answers about long COVID-19, clinical guidelines for treating long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.
Newly discovered virus is sickening cattle in Western Europe (Science)
Safety, tolerability, and immunogenicity of SPVX02, a room temperature-stabilised tetanus-diphtheria vaccine, compared to two established tetanus-diphtheria booster vaccines: a multicentre, single-blind, randomised, first-in-human phase 1 trial in the UK (eClinicalMedicine)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1347: No Short Answers for Long COVID
09 Aug 2026
01:47:26
TWiV explains research showing that Long COVID is associated with reactivation of numerous chronic viruses, including herpesviruses and anelloviruses, and with the production of autoantibodies that target neurological tissues.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1346: Clinical update with Dr. Daniel Griffin
08 Aug 2026
00:54:29
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by Erica Schwartz’ confirmation as CDC director, the GAO proposed pandemic preparedness plans, the national cyclospora outbreak and resulting two deaths, new screwworm and the scale of the Ebola outbreak in the Congo, and clear results from some of President Trump’s policies dismantling public health activites including water safety, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, FDA approval of Moderna’s mRNA vaccine for seasonal flu, how to access and pay for Paxlovid, where to go for answers about long COVID-19, how SARS-CoV-2 infections may reactivate latent viral infections, particularly Aniello virus, and contacting your federal government representative to stop the assault on science and biomedical research.
PUBLIC HEALTH PREPAREDNESS: ExpertsIdentified Actions to Improve Surveillance for Emerging Disease Threats (Government Accountability Office)
Association Between First MMR Vaccination Before Age 2 Years and Childhood Autism in a U.S. EHR Cohort of 2.5 Million Children (The Pediatric Infectious Disease Journal)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1345: Rocky Mountain Virology High
02 Aug 2026
01:18:00
TWiV travels to Colorado State University in Ft. Collins, where he speaks with Angela Bosco-Lauth, Rebekah Kading, and Mark Stenglein about their careers and their virology research.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1344: Clinical update with Dr. Daniel Griffin
01 Aug 2026
00:48:57
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the numerous attempts by states to roll back vaccine laws, the recent surge of Dengue virus cases in Sri Lanka, the national cyclospora outbreak, new screwworm and Legionnaires cases, launching of the CHaT-Ox Ebola vaccine trail, scale of the Ebola outbreak in the Congo and if cross-reactive Ebola antibodies are effective, before Dr. Griffin deep dives into the measles outbreak including the new Pennsylvania dashboard, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, where to go for answers about long COVID-19, how long COVID and ME/CFS differ and contacting your federal government representative to stop the assault on science and biomedical research.
Impact of Nirsevimab in Its Second Season on Respiratory Syncytial Virus and Non-RSV Admissions in Children Under 5 (Pediatric Infectious Disease Journal)
Waste water scan for 11 pathogens (WastewaterSCan)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1343: Batting averages and stolen bases
26 Jul 2026
01:42:21
TWiV explains research which shows that Per os infectivity factors are essential for bracovirus infection and wasp parasitism, and that periodic shifts in viral load increase risk of Hendra virus spillover from Pteropus bats.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1342: Clinical update with Dr. Daniel Griffin
25 Jul 2026
00:39:35
In his weekly clinical update, Daniel Griffin and Vincent Racaniello explore the source/not source of the national cyclospora outbreak, trust in the FDA to correctly identify the source, new screwworm, Legionnaires and cyclosporasis cases, the Ebola outbreak in the Congo and development of a novel vaccine and antiviral before Dr. Griffin deep dives into the measles outbreak including the new Pennsylvania dashboard, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, difference between high and standard dose influenza vaccines, how to access and pay for Paxlovid, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research.
FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
Influenza vaccine effectiveness against outpatient acute respiratory illness withlaboratory-confirmed influenza, United States, 2024–25 season (CID)
Effect of high-dose versus standard-dose influenza vaccines on hospitalisation outcomes and mortality in older adults: a systematic review and meta-analysis (LANCET: Healthy Longevity)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1341: Phage breaks and COVID origins
19 Jul 2026
01:39:32
TWiV explains research that reveals dual activity of a phage-encoded lysin that modulates infection dynamics in a mycobacteriophage, and refutes a proposed link between the SARS-CoV-2 furin cleavage site and mouse-adapted MERS-coronavirus MA30.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1340: Clinical update with Dr. Daniel Griffin
18 Jul 2026
00:44:20
In his weekly clinical update, Daniel Griffin and Vincent Racaniello debate if Senator Mitch McConnell’s recent hospitalization is due to post-polio syndrome or just old age, how air quality from Maine to Chicago has been affected by the Ontario wild fires, new screwworm, Legionnaires and cyclosporasis cases, the Ebola outbreak in the Congo and development of a novel vaccine and antiviral, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, where to go for answers about long COVID-19, long term effects of COVID-19 immune dysfunction including ocular and gut and contacting your federal government representative to stop the assault on science and biomedical research.
Long-term ocular symptoms following COVID-19 linked to immune dysregulation, dysautonomia and peripheral neuropathy (Nature Communications)
Vagal cholinergic denervationof the gastric mucosa in Long-COVID-19: in vivo evidence of structural autonomic dysfunction (International Journal of Infectious Diseases)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1339: Ebola up close with Tom Ksiazek
12 Jul 2026
01:50:44
Tom Ksiazek, a world-renowned virus expert with 40 years of experience on the front lines of some of the worst outbreaks the world has ever seen, joins TWiV to discuss his career, ebolaviruses in general, and the current outbreak of Bundibugyo ebolavirus in Africa.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1338: Clinical update with Dr. Daniel Griffin
11 Jul 2026
00:42:39
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are dismayed over the military deaths due to the voluntary influenza vaccination policy, FDA’s first vaccine recommendations since 2023, the efficacy of influenza vaccines, new screwworm, Legionnaires and cyclosporiasis cases, the Ebola outbreak in the DRC and Uganda and before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, publication of the blocked COVID-19 vaccine findings, where to go for answers about long COVID-19, use of antivirals in children with COVID-19, severe West Nile disease and contacting your federal government representative to stop the assault on science and biomedical research.
Efficacy and safety of rivaroxaban, colchicine, and famotidine–loratadine with specialist supportive clinical care for fatigue in patients with post-COVID-19 condition in the UK: a multisite, open-label, randomised controlled trial (LANCET: Infectious Diseases)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1337: The whitefly and the Red Queen
05 Jul 2026
01:52:32
TWiV explains research that reveals an an alternative evolutionary path of antiviral signalling in a sea anemone, and how a bacterial symbiont and a plant virus enhance insect fitness by inducing physical defenses against fungal parasites.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1336: Clinical update with Dr. Daniel Griffin
04 Jul 2026
00:23:07
In his weekly clinical update, Daniel Griffin and Vincent Racaniello lament about the new ACIP charter, how administration of the HPV vaccine has eliminated cervical cancer deaths in young women, the global economic burden of infectious disease, restoring trust in vaccinology, new screwworm cases, the Ebola outbreak in the Congo and Uganda and need for preparedness, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how to access and pay for Paxlovid, publication of the blocked COVID-19 vaccine findings, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research.
Size of the 2026 Ebola outbreak and risk of cross-border spillover from Bundibugyo virus in Ituri Province, DR Congo, and its implications for preparedness: a recalibrated stochastic modelling study (LANCET Infectious Diseases)
US CDC raises Ebola outbreak response to highest level (Reuters)
Construction of US-backed Ebola quarantine unit in Kenya is stopped (CIDRAP)
ASPR Supports Global Ebola Response While Strengthening U.S. Preparedness (Administration for Strategic Preparedness & Response)
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1335: TldR, bacterial hot rods and nullifying norovirus
28 Jun 2026
01:55:49
TWiV explains research showing how temperate phages enhance bacterial host fitness via RNA-guided flagellar remodelling, and that IgA antibody is necessary and sufficient to prevent norovirus infection in mice.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1334: Clinical update with Dr. Daniel Griffin
27 Jun 2026
00:31:01
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the global economic burden of infectious disease, restoring trust in vaccinology, the Legionnaires outbreak in Harlem, new screwworm cases, the Ebola outbreak in the Congo and Uganda and an import case into France, end of the hantavirus outbreak before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, outbreak of measles in Cook County Illionis in 2025, loss of measles elimination in the US, how to access and pay for Paxlovid, publication of the blocked COVID-19 vaccine findings, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research.
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1333: STING like a nanoparticle, float like HIV
21 Jun 2026
01:54:50
TWiV explains research showing how HIV-1 signalling remodels nuclear pores to licence infection, and development of STING agonist nanoparticles to enable coordinated mucosal-systemic immunity for durable pan-β-coronavirus protection.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV Special: Ebola virus and Andes virus with John Dye
20 Jun 2026
00:57:08
Vincent travels to ASM Microbe in Washington DC to speak with John Dye of the United States Army Medical Research Institute of Infectious Diseases about the recent outbreaks of Bundibugyo ebolavirus in Africa and Andes virus on a cruise ship.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1332: Clinical update with Dr. Daniel Griffin
20 Jun 2026
00:54:29
In his weekly clinical update, Daniel Griffin and Vincent Racaniello express concern about vaccine policy and ACIP, scaling back of the CDC’s role in global public health, shingles vaccine and dementia, new screwworm cases, the Ebola outbreak in the Congo and Uganda and where the hantavirus outbreak began, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, Virgina outbreak of measles, how to access and pay for Paxlovid, how more people were negatively impacted by influenza than COVID, discontinuing contact precautions for COVID, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research.
Today we filed a motion asking the First Circuit to expedite our appeal of the district court’s order in the AAP lawsuit that left ACIP—the nation’s vaccine advisory committee—without a quorum (X)
CDC advisers drop decades-old universal hepatitis B birth dose recommendation, suggest blood testing after 1 dose (CIDRAP)
HHS asks for expedited appeal of court ruling on US vaccine policy (CIDRAP)
New Plan Scales Back C.D.C.’s Work on Diseases Abroad (NY Times)
Safety and Immunogenicity of 1 or 2 Additional Doses of the Adjuvanted Recombinant Zoster Vaccine Administered 5–6 Years After Primary Vaccination in Adults ≥50 Years (OFID)
Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1331: A drug for cervical cancer
14 Jun 2026
01:58:16
TWiV explains research showing that dairy cows are infected with low doses of influenza A(H5N1) and do not transmit efficiently to other animals, and covalent inhibitors of human papillomavirus type 16 E6 protein that restore p53 function and suppress growth of HPV-driven tumors in vivo.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1330: Clinical update with Dr. Daniel Griffin
13 Jun 2026
01:11:05
In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined “Hantavirus” patients for the governmental propaganda machine, use of ribavirin and other antivirals for Hantavirus associated cardiopulmonary disease, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Bangladesh, as well as in a daycare center in Texas in 2025, how to access and pay for Paxlovid, FDA approval of a second COVID-19 antiviral drug, where to go for answers about long COVID-19, use of convalescent sera for COVID-19 treatment and contacting your federal government representative to stop the assault on science and biomedical research.
One Year In: Public Views of a Changing Public Health Landscape (Harvard School of Public Health)
Rotavirus Vaccine Coverage and Potential Barriers Among US Children Born From 2007 to 2024 (Pediatrics)
Texas reports New World screwworm in 3-week-old calf (CIDRAP)
USDA Confirms First Case of New World Screwworm in a Dog in Lea County, New Mexico, Fourth Case in Texas (USDA: Animal and Plant Health Inspection Service)
Confirmed Detections of New World Screwworm (USDA: Animal and Plant Health Inspection Service)
Mexico reports more human New World screwworm infections (CIDRAP)
Frequency and persistence of post-acute symptoms after chikungunya, dengue, Zika and malaria in travellers: a prospective multi-centre study (Journal of Travel Medicine)
Some hantavirus-exposed cruise ship passengers return home to finish quarantine (CNN)
Use of tocilizumab for severe hantavirus pulmonary syndrome: a MEURI case series with contextual comparisons (LANCET: Infectious Diseases)
First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (Clinical Microbiology and Infection)
Real-world emergence of nirsevimab resistance in breakthrough infections with respiratory syncytial virus-B: a multicentre observational study in France (LANCET: Microbe)
Waste water scan for 11 pathogens (WastewaterSCan)
Shionogi Announces FDA Approval of XOCOVA® (ensitrelvir), the First and Only Oral Option to Help Prevent COVID-19 Following Exposure (Businesswire)
SARS-CoV-2 viral shedding and vaccination‑modified effects of oral antivirals in older COVID-19 patients: a retrospective cohort study in Hong Kong (International Journal of Infectious Diseases)
SARS-CoV-2 vaccination and attenuation of breakthrough infection severity: A systematic global review and meta-analysis (CID)
Metformin on the Presence of COVID-19 Symptoms 6 Months after Infection: The ACTIV-6 Randomized Clinical Trial (CID) Reaching out to US house representative
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1329: How HIV-1 goes nuclear
07 Jun 2026
01:50:33
TWiV explains research showing limited transmission of cervid prions to nonhuman primates, and the finding that cone-shaped HIV-1 capsids are transported through intact nuclear pores.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1328: Clinical update with Dr. Daniel Griffin
06 Jun 2026
01:00:57
In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined “Hantavirus” patients for the governmental propaganda machine, use of ribavirin and other antivirals for Hantavirus associated cardiopulmonary disease, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Bangladesh, as well as in a daycare center in Texas in 2025, how to access and pay for Paxlovid, FDA approval of a second COVID-19 antiviral drug, where to go for answers about long COVID-19, use of convalescent sera for COVID-19 treatment and contacting your federal government representative to stop the assault on science and biomedical research.
Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO)
WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo)
First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (Clinical Microbiology and Infection)
Shionogi Announces FDA Approval of XOCOVA® (ensitrelvir), the First and Only Oral Option to Help Prevent COVID-19 FollowingExposure (Businesswire)
FDA Approves Oral Antiviral to Prevent COVID-19 After Exposure (MEDPAGE TODAY)
The impact of COVID-19 vaccination on long-term risk of new-onset atrial fibrillation/flutter after COVID-19 infection: A retrospective cohort study(PLoS One)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1327: Influenza viruses in the MIST
31 May 2026
01:59:33
TWiV explains research on human influenza virus transmission that reveals heterogeneous expulsion of infectious virus into air, and how gut bacteriophages dictate inflammation heterogeneity through tuning the phage-bacteria-sphingosine-intestine axis in Crohn’s disease.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1326: Clinical update with Dr. Daniel Griffin
30 May 2026
00:38:49
In his weekly clinical update, Daniel Griffin and Vincent Racaniello comment on incidences of locally transmitted malaria in the US, mpox diagnostics, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda including vaccine candidates before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Texas in 2025, how to access and pay for Paxlovid, where to go for answers about long COVID-19, casual association of auto-antibodies and COVID complications and contacting your federal government representative to stop the assault on science and biomedical research.
CDC Operational Guidance for Investigating Locally Acquired Mosquito-Transmitted Malaria — United States, 2026 (CDC: MMWR)
Performance of five mpox antigen-based rapid diagnostic tests tested on lesion swabs from patients with suspected mpox from the Kinshasa province of DR Congo: a diagnostic accuracy study (LANCET: Infectious Diseases)
Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO)
WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo)
WHO chief says fast-moving Ebola epidemic is outpacing response efforts (Reuters)
US CDC seeks staff for Ebola screening as outbreak response expands (Reuters)
Trump Administration to Send Americans Exposed to Ebola to Kenya (NY Times)
Single Immunization With a Monovalent Vesicular Stomatitis Virus–Based Vaccine Protects Nonhuman Primates Against Heterologous Challenge With Bundibugyo ebolavirus (JID)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1325: Sticky flu with Hannah Rowe
24 May 2026
00:57:06
Vincent travels to Oregon State University in Corvallis to meet up with Hannah Rowe to talk about her career and her work demonstrating how the interaction of influenza A virus and Streptococcus pneumonia influences transmission.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1324: Clinical update with Dr. Daniel Griffin
23 May 2026
00:45:50
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss withdrawal of the ACIP charter published in April 2026, the first council meeting on antibiotic resistant bacteria, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, transmission of SARS-CoV-2 through the air including ventilation systems, how to access and pay for Paxlovid, where to go for answers about long COVID-19, early use of antiviral drugs for COVID-19 patients and contacting your federal government representative to stop the assault on science and biomedical research.
Visualizing the hantavirus cruise outbreak in maps and charts (CNN)
Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO)
Ebola outbreak response intensifies in DRC and Uganda as cases mount (DG: Alerts)
WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo)
Vaccine experts debate options to combat outbreak of unusual Ebola strain (Science)
US promises to fund clinic established to treat Ebola (X-USForeignAssist)
U.S.-Bound Flight Diverted to Canada Because of Ebola Restrictions (NY Times)
Potential airborne transmission of SARS-COV-2 through bathroom ventilation ducts associated with an outbreak in a residential building in Santander, Spain, 2020 (PLoS One)
Early antiviral use may lower risk of long COVID in mildly ill patients, aid recovery from infection (CIDRAP)
Early-Phase Oral Antiviral Use and Post–COVID-19 Condition in Outpatients (JAMA Network OPEN)
Impact of Early Oral Antiviral Use for Outpatients With COVID-19 on Healthcare Utilization and Recovery (ANCHOR-02) (International Journal of Infectious Diseases) Reaching out to US house representative
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1323: One influenza infection, two patients
17 May 2026
01:48:49
TWiV explains mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines, and how toll-like receptor 7 alters the maternal immune landscape during influenza A infection to increase maternal and fetal morbidity,
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1322: Clinical update with Dr. Daniel Griffin - Hantavirus special
16 May 2026
00:53:12
In his weekly clinical update, Daniel Griffin and Vincent Racaniello reviewed the latest developments surrounding the hantavirus outbreak, including new interim guidance from the Centers for Disease Control and Prevention for the management of infectious cases, whether the CDC may be downplaying the significance of the outbreak because of public backlash following the COVID-19 pandemic, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, benefit of maternal vaccination against RSV for infants, efficacy and safety of a mRNA influenza vaccine how to access and pay for Paxlovid, where to go for answers about long COVID-19, multisystem inflammatory syndrome in children and contacting your federal government representative to stop the assault on science and biomedical research.
CDC Is Walking a Tightrope With Its Response to Hantavirus (Wall Street Journal)
What Happened on the Hantavirus Cruise, According to a Doctor On Board (The Atlantic)
Andes hantavirus outbreak on a cruise ship – an ESCMID Emerging Infections Subcommittee (EIS) rapid assessment (CMI: Clinical Microbiology and Infection)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1321: Phage cross talk and cross reactions
10 May 2026
01:52:04
TWiV explains how cross-reactive anti-prophage antibodies and bacterial heteroresistance is implicated in phage therapeutic failure, and how phages communicate across species to shape microbial ecosystems.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1320: Clinical update with Dr. Daniel Griffin
09 May 2026
00:44:26
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the outbreak of Hantavirus on a cruise ship and its potential for person-person transmission, how cessation of funding for global health by the Trump administration has compromised American health and well being, as well as the description of paralytic poliomyelitis outbreaks in Central Africa associated with the administration of nOPV2, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, association of ear infections in children with RSV, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, where to go for answers about long COVID-19, multisystem inflammatory syndrome in children and contacting your federal government representative to stop the assault on science and biomedical research.
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1319: An earful of SARS-CoV-2
03 May 2026
01:43:53
TWiV explains the emergence of vaccine-derived poliovirus strains from the novel oral polio vaccine in the Central African Republic, and the infection of spiral ganglion neurons in the inner ear by SARS-CoV-2, which may explain hearing loss in humans.
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Content in this podcast should not be construed as medical advice.
TWiV 1318: Clinical update with Dr. Daniel Griffin
02 May 2026
01:08:31
In his weekly clinical update, Dr. Griffin and Vincent Racaniello note the uncertain future of the National Science Foundation amid shifting U.S. funding priorities and governance; the rise of China as a global research powerhouse; ongoing advances and controversies in vaccines shaped by the World Health Organization and the Centers for Disease Control and Prevention; vaccine policy battles in Florida; European approval of the moderna mCOMBRIAX, COVID-19 and influenza vaccine, the mounting evidence supporting preventive vaccination strategies including that for HPV and the HepB birth dose; the spread of drug-resistant infections and the resurgence of HIV in Zambia; and the enduring public trust in scientists despite political turbulence, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the efficacy of the influenza vaccine for children, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, use of remdesivir for RSV, how administration of Paxlovid did not affect hospitalization of high-risk vaccinated patients, where to go for answers about long COVID-19, if SARS-CoV-2 infection may facilitate EBV reactivation, exercise for treating long COVID and contacting your federal government representative to stop the assault on science and biomedical research.
Scientists Esteemed by Public, with Vaccine Scientists Seen as Similar to Scientists in General (Annenberg: Public Policy Center, University of Pennsylvania)
RFK Jr. is holding up $600M in vaccines for poor countries (Politico)
Trump Withdraws Nomination of Casey Means for Surgeon General (NY Times)
What? Benefit of preventive strategies like vaccination? Incidence of human papillomavirus infections in women aged 27 years and older in the US: A federated data network study (International Journal of Infectious Diseases)
Economic Impact of Delaying the Infant Hepatitis B Vaccination Schedule (JAMA Pediatrics)
Impact of Removing the Universal Hepatitis B Birth-Dose Vaccination in the US (JAMA Pediatrics)
Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective observational study (LANCET: Infectious Diseases)
First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID)
Waste water scan for 11 pathogens (WastewaterSCan)
Acute COVID-19 is associated with altered CD8 T-cells indicative of impaired ability to control Epstein–Barr virus reactivation (Medical Microbiology and Immunology)
Exercise and Weekly Sirolimus (Rapamycin) in Older Adults: RAPA-EX-01 Randomised, Double-Blind, Placebo-Controlled Trial (Journal of Cachexia, Sarcopenia and Muscle)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1317: Dead shrimp walking
26 Apr 2026
01:41:43
TWiV explains a study showing that viral DNA load in blood and saliva varied markedly with age, time of day season, sex, and depended on dozens of genetic loci, and identification of an emerging human eye disease associated with aquatic virus zoonotic infection.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1316: Clinical update with Dr. Daniel Griffin
25 Apr 2026
00:53:17
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are distressed by RFK Jr’s testimony in front of Congress, surges in rotavirus infections and the staggering number of people who believe in unproven claims about vaccines and science, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the fatal consequences of measles infection, prevalence of influenza and other respiratory infections in dead people, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, results from a human RSV challenge study, where to go for answers about long COVID-19, negatively associated school-related outcomes in children and adolescents with long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.
Prevalenceof influenza and other respiratory viral infections in deceased persons: a population-based observational study over four influenza seasons (Clinical Microbiology and Infection)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
Clinical and economic benefits of seasonal COVID-19 vaccination in Germany: results from the ROUTINE-COV19 Study, September 2022 to March 2024 (Eurosurveillance)
Effectiveness and safety of molnupiravir among patients with mild to moderate COVID-19: a prospective, observational, cohort study (Scientific Reports)
Divergent inflammatory and neurology-related protein levels in long COVID following primary and breakthrough SARS-CoV-2 infections (Communications Medicine)
School Difficulties and Long COVID in Children and Adolescents (Academic Pediatrics)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1315: Jabs for bats
19 Apr 2026
01:50:10
TWiV explains a study showing that the wildlife trade, including live-animal markets, is a major driver of animal-to-human pathogen transmission, and ecological vaccination, a strategy to prevent zoonotic spillover from bats.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1314: Clinical update with Dr. Daniel Griffin
18 Apr 2026
00:47:00
TWiV 1314: Clinical update with Dr. Daniel Griffin April 17, 2026
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed but not surprised by poll results suggesting most Americans doubt vaccine safety, that the head of the CDC and NIH delayed release of a report on the safety of the COVID-19m vaccine, how Nature works to spread disease without the help of the lab and the about face of the Trump administration to nominate a pro-vaccine candidate for CDC director, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how the influenza vaccine may attenuate stroke and acute cardiac disease following virus infection, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, how the COVID-19 pandemic was a ‘negative’ for one’s mortality where to go for answers about long COVID-19, potential therapies for the pediatric long COVID population and contacting your federal government representative to stop the assault on science and biomedical research.
Influenza vaccination attenuates acute myocardial infarction and stroke risk following influenza infection: a register-based, self-controlled case series study, Denmark, 2014 to 2025 (Eurosurveillance)
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Content in this podcast should not be construed as medical advice.
TWiV 1313: Maybe they're all dementia vaccines
12 Apr 2026
01:55:45
TWiV reviews evidence that influenza standard and high-dose vaccines reduce risk of Alzheimer’s dementia, and spread of deltaviruses by a viral Trojan horse mechanism.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1312: Clinical update with Dr. Daniel Griffin
11 Apr 2026
00:44:44
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are aghast at the CDC’s decision to no longer test for rabies and mpox and the revised charter for its the advisory committee on immunization practices, an outbreak of E. coli illness in raw cheese, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, clinical practice guidelines for treating COVID-19, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, if the nasal microbiome modulates COVID-19 disease severity, reviews the use of steroid, antibiotics, anticoagulants and IVIG for treating COVID-19 including long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.
2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19(CID)
2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Baricitinib vs. Tocilizumab (CID)
ImmunobridgingAnalysis of Pemivibart for the Treatment of COVID-19 – A Therapeutic Gap for the Immune Compromised Remains (OFID)
PEMGARDA® is authorized for use in certain moderately to severely immunocompromised patients to help prevent COVID-19 (Pemgarda)
The effect of corticosteroids, antibiotics, and anticoagulants on the development of post-COVID-19 syndrome in COVID-19 hospitalized patients 6 months after discharge: a retrospective follow up study (Clinical and Experimental Medicine)
Intravenous immunoglobulin treatment for long COVID: a case report of clinical and immunological findings (LANCET: Infectious Diseases)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1311: Jayhawks go viral
05 Apr 2026
01:32:53
Vincent visits the University of Kansas and speaks with Tony Fehr, Robin Orozco, Juergen Richt and Rob Unckless about their careers and the research ongoing in their laboratories.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1310: Clinical update with Dr. Daniel Griffin
04 Apr 2026
00:40:09
In his weekly clinical update, Dr. Griffin and Vincent Racaniello cover if the “five-second” rule for things that fall on the floor apply to surgical equipment, an outbreak of E. coli illness caused by raw cheese before Dr. Griffin then deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, strain selection for the 2026-2027 season influenza vaccine by the FDA, if standard or high dose influenza vaccination influences dementia protection, a new variant of SARS-CoV-2, how to access and pay for Paxlovid, specific effects of Paxlovid and contacting your federal government representative to stop the assault on science and biomedical research.
The “five-second” rule for dropped food: does it apply to dropped medical objects in the operating room? A randomized study of disinfection approaches for contaminated arthroplasty implants (Infection Control & Hospital Epidemiology)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1309: Maybe they're all cancer vaccines
29 Mar 2026
01:46:24
TWiV explains why human papillomavirus vaccine-induced immunity can block infection, unlike all other vaccines, and how respiratory viral infections such as COVID and influenza prime accelerated lung cancer growth.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1308: Clinical update with Dr. Daniel Griffin
28 Mar 2026
00:51:08
In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the resignation of a member of the advisory committee for immunization practices and the irony of his rationale that a judge slandered him, vaccinating dairy cattle against H5N1, illnesses resulting from drinking raw milk and the US norovirus outbreak, which is not cruise related, then Dr. Griffin deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, safety data of the RSV vaccine for high risk young adults, recognition of unrecognized COVID-19 deaths (but weren’t we not allow to call it a COVID-19 in 2020?), retraction of and how the ANTIBIOTIC azithromycin is NOT an antiviral drug, how to access and pay for Paxlovid, long COVID patients with neurocognitive symptoms and contacting your federal government representative to stop the assault on science and biomedical research.
Immunogenicity and Safety of the AS01E-adjuvanted Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine in Adults Aged 18–49 Years at Increased Risk of RSV Disease Compared with Adults Aged ≥60 Years (CID)
Waste water scan for 11 pathogens (WastewaterSCan)
Respiratory viral infections prime accelerated lung cancer growth (Cell)
Association between COVID-19 vaccination and sudden death in apparently healthy younger individuals: A population-based case-control study (PLoS Medicine)
Applying machine learning to identify unrecognized COVID-19 deaths recorded as other causes of death in the United States (Science Advances)
RETRACTED work: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial (International Journal of Antimicrobial Agents)
Antibiotic used in COVID patients tied to increased signs of antibiotic resistance (CIDRAP)
Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19 (Nature Microbiology)
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1307: My heart breaks for flu
22 Mar 2026
01:53:20
TWiV reviews the structural basis for Rep-mediated adeno-associated virus DNA genome packaging, how influenza virus-infected myeloid cells travel to the heart and infect cardiomyocytes, leading to IFN-fueled heart damage.
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
TWiV 1306: Clinical update with Dr. Daniel Griffin
21 Mar 2026
00:43:55
In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, ‘renaming’ of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal changes in routine immunization practices, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, expansion of the RSV vaccine licensure to include high risk yound adults, association between lung cancer and respiratory illnesses, how to access and pay for Paxlovid, effectiveness of vaccination or supplemental vitamin D to reduce the risk of long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.
Effectiveness of COVID-19 Vaccination and Prior Infections to Reduce Long COVID Risk During the Pre-Omicron and Omicron Periods (CID)
A Randomized Trial of Vitamin D Supplementation and COVID-19 Clinical Outcomes and Long COVID: The Vitamin D for COVID-19 Trial (The Journal of Nutrition)