The Transformative Ideas Podcast – Details, episodes & analysis

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The Transformative Ideas Podcast

Manuel Brenner

Science

Frequency: 1 episode/30d. Total Eps: 36

The Transformative Ideas Podcast (formerly the ACIT Science Podcast). This podcast is to provide a glimpse into the life of scientists: to learn about the ideas they are passionate about, to find out what gets them out of bed every day to face the challenges and frustrations of working at the frontier to the unknown, and to share in some of the most important lessons they have learned in their career. For inquiries, reach out to manu.brenn@gmail.com.

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Apple Podcasts

🇩🇪 Germany - naturalSciences
21/08/2026
#43
🇫🇷 France - naturalSciences
11/07/2025
#90
🇫🇷 France - naturalSciences
10/07/2025
#74
🇫🇷 France - naturalSciences
09/07/2025
#53
🇫🇷 France - naturalSciences
06/07/2025
#90
🇫🇷 France - naturalSciences
05/07/2025
#63

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https://mailchi.mp/0346443b6ddf/acit-global-signup
6 shares
https://acit-science.com/
5 shares
https://www.catf.us/about/
3 shares

https://youtube.com/@AICoffeeBreak

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Score global : 32%

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#35: Bridging Modalities: Vision, Language, and AI with Letitia Parcalabescu

Season 1 · Episode 35

Monday, August 7, 2023 • Duration 01:14:58

In this epsiode, we are joined by Letitia Parcalabescu, PhD candidate at Heidelberg University's Department of Computational Linguistics, to share her insights on the fascinating world of Multimodal Learning. As a researcher and science communicator, Letitia has been thinking about the intersection between vision and text, a frontier of machine learning that has seen immense growth in recent years, for several years. We explore her journey from physics to machine learning, unpack the influence of large language models (LLMs) on our understanding of linguistics, and delve into the relevance of vision and language interplay in machine learning. We discuss the key developments in multimodal learning, including joint embeddings, diffusion models, and LLMs, and shares her perspective on how these advancements relate to Artificial General Intelligence (AGI). Alongside her research, we discuss the value of benchmarks and performance metrics in machine learning, as well as her own research projects. Letitia offers a glimpse into a typical research day in her field, and shares her motivations and learnings from her successful YouTube channel, AI Coffee Break: https://youtube.com/@AICoffeeBreak

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#34: The Biology of Aging: From Mechanisms to Interventions with Christoph Benner

Episode 34

Wednesday, April 26, 2023 • Duration 01:22:35

In this episode, we are joined by Christoph Benner. Christoph Benner received his PhD from ETH Zurich, studying aging in model organism. We discuss the idea of treating aging as a disease, theories of aging, and some of its hallmarks. We cover the fascinating role mitochondria plays in aging and metabolism, and get into the weeds of the complex underlying biochemistry. We also discuss pragmatic tools and interventions, from most promising drugs to behavioral measures, such as intermittent, and how much of it boils down to common shared mechanism between many species. We close with discussions on the scientific process, the importance of philosophy for science. For inquiries, reach out to manu.brenn@gmail.com.

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#25: Tackling Climate Change through Carbon Capture with Lee Beck

Season 1 · Episode 25

Wednesday, March 23, 2022 • Duration 01:05:46

In this episode, host Manuel Brenner is joined by Lee Beck, international director of global carbon capture strategies for the clean air task force. In this capacity she lead the carbon capture strategy, program, and team, which is by now represented in the US, Europe, and the Middle East, and has tripled in size in recent years. This is the second episode of a 3-part miniseries that ACIT is hosting together with the CATF. The Clean Air Task Force (CATF) is a global non-profit organization working to safeguard against the worst impacts of climate change by catalyzing the rapid global development and deployment of low-carbon energy and other climate-protecting technologies through research, analysis, public advocacy leadership, and partnership with the private sector. In this episode, we go in depth into carbon capture and storage, what the state of technology is, how policy shapes incentives in the carbon capture space, how carbon capture connects to more ambitious climate goals and negative emissions, how carbon pricing has changed the landscape, what pilot projects are being built, how the US and Europe differ in mentality and how they can be complimentary, optimism and optionality, and many more topics. Find out more about the Clean Air Task Force: https://www.catf.us/about/ Stay updated with future episodes and other events ACIT is hosting: https://mailchi.mp/0346443b6ddf/acit-global-signup

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#24: The Clean Air Task Force with Armond Cohen

Friday, February 18, 2022 • Duration 01:09:56

In this episode, Manuel Brenner is joined by Armond Cohen.

Armond Cohen is co-founder and Executive Director of the Clean Air Task Force, which he has led since its formation in 1996.
The Clean Air Task Force (CATF) is a global non-profit organization working to safeguard against the worst impacts of climate change by catalyzing the rapid global development and deployment of low-carbon energy and other climate-protecting technologies through research, analysis, public advocacy leadership, and partnership with the private sector.
This is the first episode of a 3-part miniseries that ACIT is hosting together with the CATF.

In this episode, we discuss what the CATF is and how it works, current paradigms in the climate movement, the importance of optionality, why wind and solar will probably not be exclusive solutions to the issue of climate change, how to advance a carbon-free energy sector in developing countries without falling back to neo-colonial policies, optimism vs. apocalyptic thinking in the climate movement, politics and partisanship in the US and internationally and how they interact with innovation in the energy sector, what changes the endorsement of the CATF by the effective altruism foundation have made possible in recent years, and much more.

Find out more about the Clean Air Task Force:
https://www.catf.us/about/

Stay updated with future episodes:
https://mailchi.mp/0346443b6ddf/acit-global-signup

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#23: The Hidden Spring of Consciousness with Mark Solms

Friday, February 11, 2022 • Duration 01:28:40

In this episode, host Manuel Brenner talks to Mark Solms.
Mark Solms is the Chair of Neuropsychology at the University of Cape Town, President of the South African Psychoanalytical Association, and the author of 8 books and hundreds of scientific articles. His most well-known scientific contributions include discovering the brain mechanisms of dreaming, and combining psychoanalysis and neuropsychology in an approach he coined "neuropsychoanalysis".

In this episode, we primarly discuss ideas from his newest book "The Hidden Spring", which delves into the relationships between affect, its source in the brainstem, Karl Friston's free energy principle, and how it all relates to a new theory for a "hidden spring" of consciousness.
We discuss Mark Solm's motivation for combining psychoanalysis and neuropsychology and historic reasons for why the subject has been long neglected in psychology. We move on the talking about affect and valence, what role they play in our experiental life, and how they might give us a new handle for approaching a scientific theory of consciuousness. We discuss how current cortical theories of consciousness interact with problems surrounding Chalmer's hard problem of consciousness, epistemology, and metacognition, and why the current neuroscientific evidence points away from the cortical towards an affective view of consciousness.

We close by discussing the relationship of affective consciousness to Karl Friston's free energy principle and the theory that Mark Solms developed with Friston, and questions of responsibility around using this theory to build an artificial consciousness.

Click here to stay updated with new episodes.

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#22: Psychotherapy and Psychedelics with Henrik Jungaberle

Tuesday, January 18, 2022 • Duration 49:35

Dr. sc. hum. Henrik Jungaberle is the Director of the MIND Foundation and a CEO of OVID. He is a researcher, science entrepreneur, and author in public health, psychedelics, and psychotherapy.

In this episode, Henrik Jungaberle speaks with host Manuel Brenner about augmenting psychotherapy with psychedelics, how psychedelic substances can and need to be combined with therapy in a clinical setting, whether psychedelics work more strongly on the mind or on the brain, in what ways they could transform psychotherapy (and in which ways they probably won't), what role capitalism and enterpreneurship will play, how to factor in historical perspective, and many more topics.

Find out more about ACIT under acit-science.com

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#21: International Criminal Law and Human Rights with Amal Ounali

Thursday, November 25, 2021 • Duration 01:20:36

In this episode, Amal Ounali is joining our host Manuel Brenner for a discussion on international criminal law, European law, how national laws and international laws interact (and sometimes collide), human rights, discrimination, and many more topics.

Amal is studying for her Master of Law at the University of Geneva and is currently doing am exchange in the University of Utrecht, focusing on criminal law in a European and transnational context.

Find out more about ACIT under https://acit-science.com/

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#20: (Post) World Music Experimentalism with Rim Jasmin Irscheid

Episode 20

Sunday, November 7, 2021 • Duration 01:07:17

In this episode, host Manuel Brenner is joined by Rim Jasmin Irscheid. Rim is a doctoral candidate in the Music Department at King's College London, working on experimental music and 'world music' festival culture in Europe. Her research sits at the boundary between ethnomusicology and sociology.

We discuss the controversial history of the term "world music", the role music plays in narratives of integration and in the way Germany is dealing with its past, the instrumentalisation of narratives of other cultures, hallmarks of experimental music, the role of experimental music in Germany and the Middle East, making money in the modern music scene, organizing music festivals and the importance of life music, the role of Spotify and Youtube in today's music industry, affective musicianship, and many more topics.

Find out more about ACIT: https://acit-science.com/

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#19: Viruses, Pandemics and Effective Altruism with Jasper Götting

Wednesday, September 15, 2021 • Duration 01:50:41

In this episode, we are joined by Jasper Götting, PhD Candidate at the Institute of Virology of the Hannover Medical School, where his research focuses on the sequencing and monitoring of viruses.

We discuss what a virus is, the differences between RNA and DNA viruses, how we are all infected by Herpes viruses, and why this matters for organ transplants. We delve into flu viruses and corona viruses and some of their elegant and dangerous features, monitoring in the context of pandemics, virological weather forecasts, pandemic risk, manmade pandemics vs. natural pandemics, the risks of gain-of-function research, and the early warning center in Berlin.
We talk about Jasper's engagement in the Effective Altruism community and how this has shaped his career choices, about wild animal suffering, meat production, 80 000 hours, and many more topics.

The podcast is hosted by Manuel Brenner.

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#18: AI for Drug Discovery and Longevity with Noah Weber

Episode 18

Saturday, September 11, 2021 • Duration 02:09:20

In this episode, we are joined by Noah Weber, CTO and Head of Machine Learning at Celeris Therapeutics and lecturer at FH Technikum Vienna. We discuss the challenges of developing new drugs, protein degradation, the promises of AI in revolutionizing the field, the pipeline Celeris Therapeutics is developing, and how graph neural networks and geometric deep learning come in handy in modeling protein interactions. We talk about AI transforming medicine at large, from genomic-based diagnostics to a completely new outlook on longevity. We close by discussing general artificial intelligence, machine learning and statistics, reinforcement learning, AlphaGo, software development vs. fundamental research, and many more topics. The podcast is hosted by Manuel Brenner. Find out more about us on: https://acit-science.com/

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The Transformative Ideas Podcast – Details, episodes & analysis

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The Transformative Ideas Podcast – Details, episodes & analysis

Podcast details

Recent rankings

Apple Podcasts

Spotify

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Other12

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Latest published episodes

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