Explore every episode of the podcast The MicrobiomeResearchX (MRX) Podcast

Our guest today is Lina Yao at Harvard Medical School who is a finalist of the 2024 NOSTER & Science Microbiome Prize for his essay entitled " Breaking boundaries: Bacteria act as architects of host T cell modulators using bile acids.”  

Details about the prize-winning essay
www.science.org/doi/10.1126/science.adq2341

Lina Yao 
Breaking boundaries: Bacteria act as architects of host T cell modulators using bile acids.
Science385,37-37(2024).
DOI:10.1126/science.adq2341

Our guest today is Brittany Needham at Indiana University who is a finalist of the 2024 NOSTER & Science Microbiome Prize for his essay entitled " Exposed wires: A microbial metabolite influences myelination in the brain.”  

Details about the prize-winning essay
www.science.org/doi/10.1126/science.adq2344

Brittany Needham 
Exposed wires: A microbial metabolite influences myelination in the brain. 

Science 385,37-37(2024). 
DOI:10.1126/science.adq2344

Our guest today is Kazuki Nagashima at Stanford University, who is the grand prize winner of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "Blockbuster T cells in the gut: A high-resolution view of immune modulation by the gut microbiome is presented.”  

Details about the prize-winning essay
www.science.org/doi/10.1126/science.adq2335
Kazuki Nagashima

Blockbuster T cells in the gut: A high-resolution view of immune modulation by the gut microbiome is presented. 

Science385,36-37(2024).
DOI:10.1126/science.adq2335

Our guest today is Christoph A. Thaiss the Microbiology Department of the Perelman School of Medicine at the University of Pennsylvania, who is a finalist of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "A microbiome exercise: gut-brain connections drive the motivation to work out.”  

Details about the prize-winning essay

https://www.science.org/doi/10.1126/science.adi6329

Essay: A microbiome exercise

Science, 381, 6653, p. 38, 2023. 

DOI: 10.1126/science.adi6329

Related research 

L. Dohnalová et al A microbiome-dependent gut-brain pathway regulates motivation for exercise. 

Nature, 612(7941):739-747, 2022. 

DOI: 10.1038/s41586-022-05525-z. E

Our guest today is Christopher Stewart of the Translational and Clinical Research Institute at Newcastle University, who is a finalist of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "Diet-microbe-host interaction in early life: breastmilk bioactives are important to infant microbiome.”  

Details about the prize-winning essay

https://www.science.org/doi/10.1126/science.adi6318

Essay: Diet-microbe-host interaction in early life

Science, 381, 6653, p. 38, (2023)

DOI: 10.1126/science.adi6318

Related research 

C. J Stewart et al, Temporal development of the gut microbiome in early childhood from the TEDDY study. 

Nature 562 (7728): 583-588, (2018). 

DOI: 10.1038/s41586-018-0617-x. 

Our guest today is Sara Clasen of the Max Planck Institute for Biology in Tübingen, Germany, who is the recipient of the 2023 NOSTER & Science Microbiome Grand Prize for her essay entitled, “The sound of silence”. 

Details about the prize-winning essay

https://www.science.org/content/page/2023-noster-science-prize-winners

Essay: The sound of silence

Science, 381, 6653, pp. 37-38,  2023

DOI: 10.1126/science.adi6265

Related research 

Clasen SJ, Bell MEW, Borbón A, Lee DH, Henseler ZM, de la Cuesta-Zuluaga J, Parys K, Zou J, Wang Y, Altmannova V, Youngblut ND, Weir JR, Gewirtz AT, Belkhadir Y, Ley RE. 

Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor-5. 

Sci Immunol. 2023 Jan 6;8(79):eabq7001.

doi: 10.1126/sciimmunol.abq7001

Our guest today is Jennifer Hampton Hill, University of Utah is the recipient of the 2022 NOSTER & Science Microbiome Grand Prize for her work that “revealed that the resident microbiome is a promising source of previously undiscovered modulators of host β cells.”

Links to details about the prize-winning essay

https://www.science.org/content/page/2022-noster-science-prize-winners

Essay: From bugs to β cells

SCIENCE, 7 Jul 2022, Vol 377, Issue 6602, pp. 164-165 DOI: 10.1126/science.abq6051

https://www.science.org/doi/10.1126/science.abq6051

Latest research 

Jennifer Hampton Hill, Michelle Sconce Massaquoi, Emily Goers Sweeney, Elena S. Wall, Philip Jahl, Rickesha Bell, Karen Kallio, Daniel Derrick, L. Charles Murtaugh, Raghuveer Parthasarathy, S. James Remington, June L. Round, Karen Guillemin

BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass

Cell Metabolism, 34, pp. 1779-1791.e9, (2022)

https://doi.org/10.1016/j.cmet.2022.09.001.

https://www.sciencedirect.com/science/article/pii/S1550413122003916

Media Coverage 

U OF U HEALTH POSTDOCTORAL FELLOW EARNS PRESTIGIOUS NOSTER AND SCIENCE MICROBIOME PRIZE

https://uofuhealth.utah.edu/newsroom/news/2022/07/hill-noster-science-prize

Jumpstarting insulin production with microbial diversity wins NOSTER & Science Microbiome Prize

https://www.eurekalert.org/news-releases/957641

MRX website

https://noster-mrx.net/

2022 NOSTER & Science Microbiome Prize: Noster Inc and AAAS announce the grand winner and finalists of the 2022 NOSTER & Science Microbiome Prize

https://noster-mrx.net/post/700075484746317824/news-and-events

Our guest today is Erez Baruch, who recently started an internal medicine residency in a research (Physician-Scientist) track to medical oncology. Internal medicine training is conducted at the McGovern Medical School in Houston, Texas.

Erez is a finalist of the 2021 NOSTER & Science Microbiome Prize for his essay, "Microbiota modulation to fight cancer”, based on his research on “mechanisms of immunotherapy resistance and toxicity, modulation of the gut microbiota, and interaction between innate and adaptive immune cells”. 

Links to details about the prize-winning essay are available on the Noster Inc MicrobiomeResearchX (MRX) website and related AAAS Science sites.

MRX 

https://noster-mrx.net/

Summary of the research activities of the 2021 NOSTER & Science Microbiome Prize winners 

https://www.aaas.org/news/gut-brain-axis-yields-clues-neurodegenerative-disease

Essay by Erez Baruch

https://www.science.org/doi/full/10.1126/science.abi9360

Our guest today is Maria Zimmermann-Kogadeeva, who started her lab in the Genome Biology Unit at EMBL Heidelberg in 2021.

Maria is a finalist of the 2021 NOSTER & Science Microbiome Prize for her essay, "Quantifying host-microbiota interactions” based on her research on the adaptation and consequences of microbes to their surroundings in hosts.

Links to details about the prize-winning essay are available on the Noster Inc MicrobiomeResearchX (MRX) website and related AAAS Science sites.

https://noster-mrx.net/

Summary of the research activities of the 2021 NOSTER & Science Microbiome Prize winners 

https://www.aaas.org/news/gut-brain-axis-yields-clues-neurodegenerative-disease

Essay by Maria Zimmermann-Kogadeeva

https://www.science.org/doi/full/10.1126/science.abi9357

Our guest today is Eran Blacher, who is currently a senior postdoctoral fellow at Stanford School of Medicine studying the immune system-gut-brain axis in ageing and neurological disorders.

 Eran is the Grand Prize winner of the 2021 NOSTER & Science Microbiome Prize for his essay, “Can microbes combat neurodegeneration?” based on his research on the relationship between the microbiome and neurodegenerative diseases such as Alzheimer's disease.

Links to details about the prize-winning essay are available on the MicrobiomeResearchX (MRX) website and related AAAS sites. 

MRX website 

https://noster-mrx.net/

Summary of the research activities of the 2021 NOSTER & Science Microbiome Prize winners 

https://www.aaas.org/news/gut-brain-axis-yields-clues-neurodegenerative-disease

Essay by Eran Blacher

https://www.science.org/doi/full/10.1126/science.abi9353

Our guest today is Mariana Byndloss, an Assistant Professor of Pathology, Microbiology and Immunology at Vanderbilt University Medical Center, in Nashville, Tennessee. 

Mariana was one of the two finalists in the 2020 first annual NOSTER & Science Microbiome Prize for her work on “Microbial management”. 

Links to details about the prize-winning essays can be found on the MicrobiomeResearchX website.

https://noster-mrx.net/

Our guest today is Chun-Jun Guo, an assistant professor at the Jill Roberts Institute for Research in Inflammatory Bowel Disease at Weill Cornell Medicine, New York. 

CJ was one of the two finalists in the 2020 first annual NOSTER & Science Microbiome Prize for his work on “Modulating microbiome metabolites in vivo”. 

Links to details about prize-winning essay and his research can be found on the MicrobiomeResearchX website.

https://noster-mrx.net/

Our guest today is Oliver Harrison, the 2020 winner of the first annual NOSTER & Science Microbiome Prize for his work on “how skin microbes interact with the immune system to aid wound healing”.

Oliver is a Principal Investigator at Benaroya Research Institute at Virginia Mason (BRI), in Seattle.
https://www.benaroyaresearch.org/what-is-bri/scientists-labs/scientists/oliver-harrison-phd

Links to details about Oliver’s prize-winning essay and his research can be found on the MicrobiomeResearchX  website.

https://noster-mrx.net/