Explore every episode of the podcast The Last Line of Defense

In this era of uncertainty, knowledge is power. Hosted by Dr. Seth G. Jones, The Last Line of Defense offers clear and insightful analysis on the latest national security news. Each episode provides practical solutions to the toughest security questions—from war and peace around the world to the role of emerging technology in defense. 

President Trump met with President Xi in a historic bilateral meeting amid growing tensions between the United States and China. Host Seth Jones sat down with Jude Blanchette, the Distinguished Tang Chair in China Research and the inaugural director of the RAND China Research Center, for a discussion on the outcome of the meeting and China’s defense strategy moving forward.

Host Seth Jones sits down with Douglas Lute, former U.S. Ambassador to NATO, to discuss President Trump’s proposed peace plan aimed at ending the Russia-Ukraine war. This episode was recorded on November 24th, 2025.

Host Seth Jones talks with Mick Ryan, retired Australian Army Major General, about his recent visit to Ukraine's frontlines. They discuss the evolving dynamics of the war, highlighting Ukraine's successes, Russia's challenges, and key developments, including shifts in U.S. policy, the change in air defense posture, and the increasing use of long-range strikes and drones.

Host Seth Jones sits down with Juan Cruz, who served in the U.S. Intelligence Community and on the National Security Council as special assistant to the president and senior director for Western Hemisphere affairs, to discuss the U.S. military’s role in the Venezuela crisis and provide an inside look at Maduro’s armed forces.

Host Seth Jones sits down with Kari Bingen, Director of the Aerospace Security Project and a Senior Fellow in the Defense and Security Department at CSIS, and former Deputy Undersecretary of Defense for Intelligence and Security. Together, they look back at major defense and military shocks of 2025, including Russia’s poor performance, Operation Midnight Hammer, and China’s military parade, among others. They also forecast potential wildcards for 2026, including a U.S.–China deal and land strikes in Venezuela.

Host Seth Jones speaks with Dr. Ryan Berg, Director of the Americas Program and Head of the Future of Venezuela Initiative at CSIS, about Venezuela’s political landscape in the post-Maduro era, examining U.S. policy goals, shifting power structures, and what’s at stake for the country’s new president, Delcy Rodríguez.

Host Seth Jones explores the implications of modern Chinese espionage cases with David R. Shedd, former Deputy Director and Acting Director of the Defense Intelligence Agency (DIA).

Host Seth Jones speaks with Norman Roule, who served as the national intelligence manager for Iran at the Office of the Director of National Intelligence from November 2008 until September 2017. The pair discusses the ongoing protests in Iran, the regime’s response, and potential policy responses from the White House.

Host Seth Jones sits down with retired Admiral Sandy Winnefeld, the ninth Vice Chairman of the Joint Chiefs of Staff, to discuss the latest developments involving Iran. They examine the U.S. military buildup near Iran and the strategic objectives of both Iran and the United States amid rising tensions.

Host Seth Jones speaks with Kate Bachelder Odell of The Wall Street Journal about the state of Russia’s war in Ukraine as it nears its fifth year. They discuss recent remarks by J.D. Vance and Marco Rubio, Ukraine’s battlefield resilience, Russia’s mounting casualties, and the prospects for negotiations and a potential peace deal.

Host Seth Jones sits down with retired General Joseph Votel, former commander of U.S. Central Command, about the evolving situation in Iran after Operation Epic Fury. They break down the military operations, Iran’s targeting strategy, regional fallout, U.S. munitions, and the broader strategic outlook.

Host Seth Jones sits down with General David H. Petraeus, retired U.S. Army general and former director of the CIA, to discuss the latest developments in Iran, including ongoing military operations and the escalating challenge of countering drone and missile threats. They also explore the international response — from Gulf States and NATO allies to China, Russia, and regional proxies — and the wider implications for the Middle East.

Host Seth Jones sits down with Face the Nation's Margaret Brennan to break down Iran’s nuclear program and offers an overview of the domestic and international politics shaping the future of this conflict in the Middle East.

Host Seth Jones speaks with Ambassador Ryan Crocker to unpack Iran’s complex political landscape, regional power dynamics, and the role of U.S. allies as the conflict unfolds. Drawing on decades of diplomatic experience, Ambassador Crocker offers a deeply informed perspective shaped by his past service as U.S. Ambassador to Afghanistan, Iraq, Pakistan, Syria, Kuwait, and Lebanon.

Host Seth Jones sat down with Dr. Bonny Lin, CSIS Senior Adviser and Director of the China Power Project, to explore Beijing’s view of the U.S.-Iran war, including its own role, the China-Pakistan peace plan, and potential takeaways.

Norman Roule is back on the podcast with Seth Jones to provide an update on developments in Iran, including the impact of sanctions and the blockade, an assessment of who is in charge in Tehran, the current state of talks, and the role of Gulf States, Lebanon, and other countries. Mr. Roule served as the national intelligence manager for Iran at the Office of the Director of National Intelligence from November 2008 until September 2017. 

Host Seth G. Jones speaks with Lt. Gen. (Ret.) Ben Hodges, former Commanding General of U.S. Army Europe (2014–2017), about the latest developments in the Russia-Ukraine war. They examine key takeaways from the G7 Summit, assess conditions on the battlefield, and explore the mounting challenges confronting Russia’s military.

Host Seth G. Jones sat down with Ambassador (ret.) Edgard D. Kagan, former U.S. ambassador to Malaysia and newly appointed Senior Adviser and Freeman Chair in China Studies at CSIS. Together, they dissected the recent Trump–Xi meeting, examining how the visit was portrayed in the Chinese media, the challenges behind joint statements, and the dynamics surrounding Taiwan.

Host Dr. Seth G. Jones sat down with retired Marine Corps Colonel Mark Cancian to examine the U.S. munitions stockpiles after Operation Epic Fury, the challenges facing America’s defense industrial base, and what those shortfalls could mean in a future conflict with China.

Host Seth G. Jones sits down with Walter Russell Mead to examine the war in Iran, including its political implications, the state of Iran’s nuclear ambitions, and the historical forces shaping the conflict. Drawing on decades of expertise, Mead offers critical historical context and perspective as the Ravenel B. Curry III Distinguished Fellow in Strategy and Statesmanship at Hudson Institute, Global View columnist at The Wall Street Journal, and Alexander Hamilton Professor of Strategy and Statecraft at University of Florida’s Hamilton School for Classical and Civic Education.

On this episode, host Seth Jones discusses areas of bipartisan support for global engagement, including NATO, the threat posed by China, support for Ukraine, and more. He is joined by Roger Zakheim, who currently serves as the Washington Director of the Ronald Reagan Presidential Foundation and Institute, and previously General Counsel and Deputy Staff Director of the U.S. House Armed Services Committee, as well as Deputy Assistant Secretary of Defense.

Host Seth Jones welcomes back Mick Ryan, retired Australian Army Major General, for the latest on the Ukraine-Russia battlefield. The pair discussed the Ukrainian air campaign, including the use of AI and drone warfare, as well as the conditions of Russia’s frontlines.

Host Seth Jones sits down with Secretary Leon Panetta for an assessment of the Iran war, U.S. military readiness, and broader strategic challenges. Drawing on decades of experience at the highest levels of government, Panetta discusses America's national security strategy, offering insights shaped by his leadership as chairman of the Panetta Institute for Public Policy, former U.S. Secretary of Defense, and former Director of the Central Intelligence Agency.