The Lancet Psychiatry in conversation with – Details, episodes & analysis

What does the science actually say about cannabis and mental health? In this episode of In Conversation With, hosted by Dustin Graham (Deputy Editor, The Lancet Psychiatry), three leading researchers unpack a landmark collection of papers on cannabis and mental health published in the journal.

Dr. Jack Wilson (University of Sydney) breaks down a comprehensive meta-analysis of randomised controlled trials, revealing striking evidence gaps. Dr. Wayne Hall (University of Queensland) synthesises multiple forms of evidence, exploring cannabis's complex relationship with psychosis, anxiety, and depression. Professor Tom Freeman (University of Bath) zooms out to examine international cannabis policy, from decriminalisation to commercial legalisation, and what those shifts mean for psychiatric outcomes.

Together, they tackle the tension between public demand, commercial interests, and a rapidly evolving evidence base — and what policymakers and clinicians urgently need to know.

Read the full collection at thelancet.com

A Health Policy piece in our April issue by Tasdik Hasan and co-authors titled:  Co-designing a Bangla Mental Health Sign Language Bank in Bangladesh

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00334-7/fulltext

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What if you could see the voice inside your head? 

Auditory hallucinations in schizophrenia are often distressing, as the voices are often malicious and unrelenting. In a new type of immersive virtual reality-based therapy, a 3D avatar of the voice is built by the patient and therapist, and it is then confronted together during the sessions. 

In this podcast, we discuss the randomised controlled trial of a large study into this VR therapy, and we hear from one of the participants in the study and one of the study therapists, as well as the lead on the study.

Read the full article:

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00161-0?dgcid=buzzsprout_icw_podcast_July_25_lanpsy

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Transgender and gender diverse people experience disproportionately high levels of interpersonal violence, but they also face multiple barriers to receiving quality post-violence care, with knock-on effects for their mental health. 

Katrina Kennedy and Rose Pollard Kaptchuk talk with Sophia Davis about the values and preferences of trans and gender diverse people around post-violence health sector responses. Their review on this topic will inform new WHO guidelines on the health of trans and gender diverse people, and here they talk about the key themes they found.

Read the full article:

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00091-4/fulltext?dgcid=buzzsprout_icw_podcast_Jun_25_lanpsy

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Which medications should be the first choice for prescribing for anxiety in older adults? Anxiety is common in older adults, but a lot of research on medication for anxiety is done in younger adults and doesn't take into account the different needs of and side-effects risks for older adults. Andrea Iaboni talks with Sophia Davis about her group's review of medications for anxiety in older adults, discussing the evidence base to inform patients and clinicians on antidepressants, benzodiazepines, and other medications. This study is part of a series of reviews to help create new Canadian treatment guidelines; read more about the guidelines here: https://ccsmh.ca/areas-of-focus/anxiety/

Read the full Article:

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00100-2/fulltext?dgcid=buzzsprout_icw_podcast_May_25_eclinm

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Sophia Davis, senior editor at The Lancet Psychiatry, discusses research on a new digital therapy for borderline personality disorder with Philipp Klein from the University of Lubeck, Germany. 

This episode delves into the core experiences of borderline personality disorder, the innovative schema therapy-based digital intervention, and the results from the new study. Learn about the effectiveness, safety, and potential of digital therapies to affect mental health treatment, and their potential to reach more patients.

Read the full article:

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00063-X/fulltext?dgcid=buzzsprout_icw_podcast_15-04-25_lanpsy

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Helene Speyer and Marte Ustrup talk with Sophia Davis about embracing dissensus in lived experience research.

Read the full article:

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00003-3?dgcid=buzzsprout_icw_podcast_generic_lanpsy

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Peter Fonagy talks with Sophia Davis about a trial of mentalization-based treatment for antisocial personality disorder in men on community probation.

Read the full article:

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(24)00445-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanpsy

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Sophia Davis talks to Mikkel Højlund about research into the prevalence and outcomes of antipsychotics polypharmacy.

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Nguyen Tran and David Kinitz talk with Sophia Davis about conversion practices for people of sexual and gender minorities and their mental health. Read the full article: https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(24)00251-7/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanpsy

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