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Explore every episode of the podcast The Lancet Gastroenterology & Hepatology in conversation with

Dive into the complete episode list for The Lancet Gastroenterology & Hepatology in conversation with. Each episode is cataloged with detailed descriptions, making it easy to find and explore specific topics. Keep track of all episodes from your favorite podcast and never miss a moment of insightful content.

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1–48 of 48

TitlePub. DateDuration
Arndt Vogel on the NALIRICC trial of nanoliposomal irinotecan in pretreated advanced biliary tract cancer31 Jul 202400:18:23

Arndt Vogel (Toronto General Hospital) discusses the NALIRICC trial of nanoliposomal irinotecan added to fluorouracil plus leucovorin in patients with cholangiocarcinoma and gallbladder carcinoma previously treated with gemcitabine-based therapies.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00119-5?dgcid=buzzsprout_icw_podcast_generic_langas

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Nancy Baxter on the duration of colorectal cancer risk reduction with a complete colonoscopy01 Jul 202400:25:05

Nancy Baxter (University of Melbourne) discusses a population-based study on the duration of risk reduction in colorectal cancer incidence and mortality after a complete colonoscopy.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00084-0?dgcid=buzzsprout_icw_podcast_generic_langas

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Robert Krouse on surgical versus non-surgical management of malignant bowel obstruction13 Sep 202300:16:31

Robert Krouse (University of Pennsylvania) discusses the pragmatic S1316 trial of surgical versus non-surgical management for patients with malignant small bowel obstruction.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00191-7/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Marc Rothenberg on a trial of benralizumab in eosinophilic gastritis10 Aug 202300:14:29

Marc Rothenberg (University of Cincinnati College of Medicine) discusses a new trial assessing the efficacy and safety of benralizumab in patients with eosinophilic gastritis, and how the surprising findings might change our understanding of eosinophilic gastrointestinal diseases.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00145-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Michael Pavlides on non-invasive tests for predicting clinical outcomes in non-alcoholic fatty liver disease12 Jul 202300:17:41

Michael Pavlides (University of Oxford) discusses work by the LITMUS Consortium on the prognostic performance of non-invasive tests in patients with non-alcoholic fatty liver disease.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00017-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Jasmohan Bajaj on global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis07 Jun 202300:12:48

Jasmohan Bajaj (Virginia Commonwealth University and Central Virginia Veterans Healthcare System, Richmond, VA, USA), on behalf of the CLEARED Consortium, discusses a prospective observational cohort study examining global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00098-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Adelina Artenie on the incidence of HIV and HCV in people who inject drugs10 May 202300:17:15

Adelina Artenie (University of Bristol, UK) discusses a systematic review and meta-analysis exploring the incidence of HIV and HCV among people who inject drugs, and associations with age and sex or gender.

Read the full article:
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00018-3/fulltext?dgcid=buzzsprout_icw_podcast_langas_lancet

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Johan Burisch on the costs of inflammatory bowel disease in high-income settings12 Apr 202300:20:00

Johan Burisch (Copenhagen University Hospital, Denmark) discusses the findings and recommendations of The Lancet Gastroenterology & Hepatology Commission on the cost of inflammatory bowel disease in high-income settings.

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The cost of inflammatory bowel disease in high-income settings

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Edouard Louis on the SPARE trial of infliximab or immunosuppressant withdrawal in Crohn’s disease08 Feb 202300:21:30

Edouard Louis (University Hospital CHU of Liège) discusses the SPARE randomised controlled trial of infliximab or concomitant immunosuppressant withdrawal in patients with Crohn’s disease.

Read the full article:
Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn's disease on combination therapy (SPARE)

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Paula Ghaneh on the ESPAC5 trial of neoadjuvant therapy in borderline resectable pancreatic cancer23 Jan 202300:20:20

Paula Ghaneh (University of Liverpool) discusses the ESPAC5 randomised controlled trial of short-course neoadjuvant therapy compared with immediate surgery for patients with borderline resectable pancreatic ductal adenocarcinoma.

Read the full article:
Immediate surgery compared with short-course neoadjuvant gemcitabine plus capecitabine, FOLFIRINOX, or chemoradiotherapy in patients with borderline resectable pancreatic cancer (ESPAC5)

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Dan Turner on vedolizumab in children with IBD06 Jan 202300:14:51

Dan Turner (Shaare Zedek Medical Center) discusses the VEDOKIDS study on the safety, effectiveness, and dosing of vedolizumab in children with IBD.

Read the full article:
Outcomes, dosing, and predictors of vedolizumab treatment in children with inflammatory bowel disease (VEDOKIDS)

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Simon Baunwall on faecal microbiota transplantation for first or second Clostridioides difficile infection09 Nov 202200:15:21

Simon Baunwall (Aarhus University Hospital) discusses the EarlyFMT trial, a randomized placebo-controlled trial of faecal microbiota transplantation for first or second Clostridioides difficile infection.

Read the full article:
Faecal microbiota transplantation for first or second Clostridioides difficile infection (EarlyFMT)

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Sanna Nybacka and Magnus Simrén on a trial of low FODMAP diets versus low carbohydrate diets in IBS17 May 202400:23:16

Sanna Nybacka and Magnus Simrén (University of Gothenburg) discuss the CARIBS randomised controlled trial of a low FODMAP diet versus a low-carbohydrate diet versus pharmacological treatment in IBS.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00045-1/fulltext?dgcid=buzzsprout_tlv_podcast_generic_langas

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James Alexander on immune responses to COVID-19 vaccination in patients with IBD05 Oct 202200:13:48

James Alexander (Imperial College London) discusses the latest findings from the VIP case-control study, which is investigating COVID-19 vaccine immune responses in immunosuppressed patients with inflammatory bowel disease.

Read the full article:
COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP)

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Filip Knop on liraglutide for bile acid diarrhoea07 Sep 202200:15:02
Edward Kim on radiation segmentectomy for unresectable very early to early stage hepatocellular carcinoma04 Aug 202200:14:06

Edward Kim (Icahn School of Medicine at Mount Sinai) discusses the single-arm RASER study of radiation segmentectomy for patients with unresectable very early to early stage hepatocellular carcinoma.

Read the full article:
Radiation segmentectomy for curative intent of unresectable very early to early stage hepatocellular carcinoma (RASER): a single-centre, single-arm study

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Joep Ijspeert on serrated polyp detection and risk of interval post-colonoscopy colorectal cancer06 Jul 202200:10:26

Joep Ijspeert (Amsterdam University Medical Center) discusses a population-based study exploring the detection of proximal serrated polyps and interval post-colonoscopy colorectal cancer risk.

Read the full article:
Serrated polyp detection and risk of interval post-colonoscopy colorectal cancer: a population-based study

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Elise Meima-van Praag on surgical closure for Crohn’s disease perianal fistulas14 Jun 202200:09:50

Elise Meima-van Praag (Amsterdam University Medical Centre) discusses the PISA-II trial, investigating short-term anti-TNF therapy with surgical closure versus anti-TNF therapy for perianal fistulas in Crohn's disease.

Read the full article:
Short-term anti-TNF therapy with surgical closure versus anti-TNF therapy in the treatment of perianal fistulas in Crohn's disease (PISA-II)

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Juan Pablo Arab on NAFLD public health policies in the Americas09 May 202200:17:06

Juan Pablo Arab (Catholic University of Chile) discusses the current burden of NAFLD and the landscape of public health policies related to the disease in the Americas.

Read the full article:
The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas

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Sarah Blach on hepatitis C virus epidemiology06 Apr 202200:08:57

Sarah Blach (CDA Foundation) summarises the latest analysis of global hepatitis C virus epidemiology and cascade of care by the Polaris Observatory HCV Collaborators.

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Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020: a modelling study

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Sunil Solomon on a minimal monitoring approach for hepatitis C virus infection23 Mar 202200:15:02

Sunil Solomon (Johns Hopkins University) discusses a study of a minimal monitoring approach for treating patients with hepatitis C virus infection.

Read the full article:
A minimal monitoring approach for the treatment of hepatitis C virus infection (ACTG A5360 [MINMON]): a phase 4, open-label, single-arm trial

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Rupert Leong on oral faecal microbiota transplantation in ulcerative colitis09 Mar 202200:13:43

Rupert Leong (University of Sydney) discusses a new double-blind, randomised, placebo-controlled trial of oral faecal microbiota transplantation for patients with active ulcerative colitis.

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Lyophilised oral faecal microbiota transplantation for ulcerative colitis (LOTUS)

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Swati Patel on early-onset colorectal cancer09 Feb 202200:19:27

Swati Patel (University of Colorado Anschutz Medical Center) discusses the epidemiology, clinical features, biology, risk factors, and opportunities for prevention and detection of early-onset colorectal cancers.

Read the full article:
The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection

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Nuru Noor on the PROFILE trial of biomarker-stratified treatment in newly diagnosed Crohn's disease07 May 202400:19:55

Nuru Noor (University of Cambridge) discusses the PROFILE trial of biomarker-stratified treatment strategies in people with newly diagnosed Crohn's disease.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00034-7/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Emilie Breekveldt on FIT-based screening for colorectal cancer in the Netherlands10 Dec 202100:09:39

Emilie Breekveldt (Erasmus Medical Center, Netherlands) discusses a new analysis of the faecal immunochemical testing-based colorectal screening programme in the Netherlands. 

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00368-X/fulltext

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Wendy Spearman on non-alcoholic fatty liver disease in sub-Saharan Africa11 Nov 202100:22:34

Wendy Spearman (University of Cape Town) discusses a Series on the emergence of non-alcoholic fatty liver disease in Sub-Saharan Africa and the challenges it presents.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00296-X/fulltext

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Tim Vanuytsel on spore-forming probiotics in functional dyspepsia09 Sep 202100:07:02

Tim Vanuytsel (University of Leuven) discusses a new trial of spore-forming probiotics in functional dyspepsia.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00226-0/fulltext

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Raymond Henderson on the economic burden of colorectal cancer12 Aug 202100:11:20

Raymond Henderson (Queen’s University Belfast) discusses a new analysis of the economic burden of colorectal cancer in Europe.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00147-3/fulltext

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Sigurður Ólafsson on eliminating hepatitis C in Iceland22 Jun 202100:13:09

Sigurður Ólafsson (Landspitali University Hospital) discusses newly published results from the nationwide programme to eliminate hepatitis C virus in Iceland. 

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00137-0/fulltext

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Caroline Ovadia on intrahepatic cholestasis of pregnancy03 Jun 202100:12:25

Caroline Ovadia (King’s College London) discusses an individual participant data meta-analysis on the treatment of intrahepatic cholestasis of pregnancy with ursodeoxycholic acid.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00074-1/fulltext

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Matthew Akiyama on hepatitis C in prisons12 Apr 202100:07:06

Matthew Akiyama (Montefiore Medical Center and Albert Einstein College of Medicine, USA) discusses a Review on hepatitis C elimination among people incarcerated in prisons.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(20)30365-4/fulltext

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Monika Sarkar on reproductive health in women with liver disease11 Mar 202100:08:15

Monika Sarkar (University of California San Francisco, USA) discusses her Comment on reproductive health in women with chronic liver disease.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00055-8/fulltext

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Yusuke Shimakawa on a simple score for hepatitis B treatment eligibility in Africa22 Apr 202400:20:54

Yusuke Shimakawa (Institut Pasteur) discusses the development and evaluation of a simple score for hepatitis B treatment eligibility in Africa.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00449-1?dgcid=buzzsprout_icw_podcast_generic_langas

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Mads Israelsen on validating the new steatotic liver disease nomenclature in people with excessive alcohol intake12 Mar 202400:16:39

Mads Israelsen (Odense University Hospital) discusses a study to validate the new nomenclature of steatotic liver disease in patients with a history of excessive alcohol intake.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00443-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Louise Dye on the role of expectancy and gluten in non-coeliac gluten sensitivity01 Mar 202400:23:19

Louise Dye (University of Leeds) discusses a trial exploring the role of expectancy and gluten ingestion on symptoms in people with non-coeliac gluten sensitivity.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00317-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Tzu-Chan Hong on the primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region19 Dec 202300:14:40

Tzu-Chan Hong (National Taiwan University Cancer Centre) discusses a systematic review and meta-analysis on primary antibiotic resistance of Helicobacter pylori between 1990 and 2022 in the Asia-Pacific region.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00281-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Sarah Moen on metachronous colorectal cancer risk according to Lynch syndrome pathogenic variant after colectomy29 Nov 202300:14:45

Sarah Moen (Erasmus University Medical Center) discusses a retrospective cohort study examining the risk of metachronous colorectal cancer after partial or extensive colectomy in carriers of different pathogenic Lynch syndrome variants.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00228-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Anna Emilie Kann on the causes of mortality in patients with alcohol-related liver disease12 Oct 202300:16:19

Anna Emilie Kann  (Zealand University Hospital, Denmark) discusses a population-based study done in Denmark exploring the causes of mortality in patients with alcohol-related liver disease.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00192-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Cathy Lu on intestinal ultrasound for assessing and monitoring Crohn's disease small bowel strictures12 Dec 202400:11:15

Cathy Lu (University of Calgary) discusses a consensus statement on the use of intestinal ultrasound for assessing and monitoring small bowel strictures in Crohn's disease.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00265-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Peter De Cruz on the PREDICT-UC trial of intensified versus standard dose infliximab for steroid-refractory acute severe ulcerative colitis06 Nov 202400:14:42

Peter De Cruz (University of Melbourne) discusses the PREDICT-UC trial of intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00200-0?dgcid=buzzsprout_icw_podcast_generic_langas

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Shahida Din and Beatriz Gros on the harms associated with receiving placebo in trials of drugs for inflammatory bowel disease01 Nov 202400:34:15

Shahida Din (Western General Hospital, Edinburgh) and Beatriz Gros (Reina Sofía University Hospital, Cordoba) discuss two new papers on the harms associated with receiving placebo in induction and maintenance trials of biological therapies and small molecules in inflammatory bowel disease.

Read the full articles:
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00264-4/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00233-4/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Hannes Hagström on screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes10 Jan 202500:21:23

Hannes Hagström discusses a study investigating the feasibility of screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00313-3/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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John Chia on the ASCOLT trial of adjuvant aspirin for colorectal cancer06 Mar 202500:13:29

John Chia discusses the results of the ASCOLT trial, which explored the effect of aspirin after completion of standard adjuvant therapy for patients with colorectal cancer.

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https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00387-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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Julia Mayerle on the validation of plasma multimetabolite signatures for patients at risk of or with suspected pancreatic ductal adenocarcinoma19 Jun 202500:26:52

Can a multi-metabolite blood test improve early pancreatic cancer detection? We spoke to Julia Mayerle about the METAPAC study, which sought to validate the ability of plasma metabolic signatures to find resectable tumors and reduce unnecessary invasive procedures in high-risk patients.

Read the full article:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00056-1/fulltext?dgcid=buzzsprout_icw_podcast_June_25_langas

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Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis09 Apr 202500:19:05

How does acute kidney injury presentation and management differ globally for patients hospitalised with cirrhosis? 

We spoke to Salvatore Piano, corresponding author of the landmark International Club of Ascites GLOBAL AKI study, about new data on regional variations in severity, phenotype, treatment, and outcomes across 5 continents.

Read the full article:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00006-8/fulltext?dgcid=buzzsprout_icw_podcast_generic_langas

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