Explore every episode of the podcast The Immunology Podcast
| Title | Pub. Date | Duration | |
|---|---|---|---|
| Ep. 86: “Myeloid Cells” Featuring Dr. Kipp Weiskopf | 27 Aug 2024 | 01:09:32 | |
Guest:
Dr. Kipp Weiskopf is a Valhalla Fellow at the Whitehead Institute. His research focuses on unlocking the therapeutic potential of macrophages for the benefit of cancer patients. He talks about the role of macrophages in the tumor environment and how targeting the CD47/SIRPα axis can induce phagocytosis of cancer cells. He also discusses starting spin-off companies to advance cancer therapies. Featured Products and Resources:
Organoids with an Immune Compartment – Researchers generated human intestinal immuno-organoids to investigate intestinal inflammation triggered by cancer-targeting biologics in patients. Gene Repression in Tregs – The transcription factor Ikaros binds to Foxp3 to inhibit the expression of target genes in Tregs. γδ T-Cell Antigen Receptor Structure – Scientists used cryo-electron microscopy to determine the structure of of the T-cell receptor found on the surface of γδ T cells. Autoimmune Organ Damage – Tissue-resident NKp46+ innate lymphoid cells are crucial signal amplifiers of disease-associated macrophage expansion and epithelial cell injury in lupus nephritis. Image courtesy of Dr. Kipp Weiskopf Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 85: “Reproductive Immunology” Featuring Dr. Adrian Erlebacher | 13 Aug 2024 | 01:17:00 | |
Guest:
Dr. Adrian Erlebacher is a Professor in the Department of Laboratory Medicine at the University of California, San Francisco. His lab studies how the developmental properties of a tissue influence its ability to mount a successful immune response. He talks about immune tolerance in pregnancy and how the maternal–fetal interface affects pregnancy outcomes. Featured Products and Resources: The Immunology Science Round UpImmune Cells in the Skull – The glioblastoma-linked immune-cell niche in the human skull provides an unanticipated resource and concept of acute tumor reactivity in the proximal bone marrow. Nasal Vaccine Reactions – Nasal vaccination induces B cell expansion in the subepithelial dome of nasal-associated lymphoid tissues. Airway Microbiota Across the Lifespan – Lifestyle factors are related to oral microbiota and environment is related to nasopharyngeal microbiota. Tregs in the Gut – Researchers used a chemogenetic screen to reveal functional neuroimmune interactions in the gut. Image courtesy of Dr. Adrian Erlebacher Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2024™: Day 5 | 08 May 2024 | 00:18:15 | |
In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the final of five special episodes from the meeting, where Brenda and Jason talk about sessions including the dysfunction of exhaustive T cells enforced by MCT11-mediated lactate metabolism and extrafollicular differentiated B cells, presented by former podcast guest Dr. Frances Lund. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 5: “Plasmodium Infection” Featuring Drs. Judy Lieberman and Caroline Junqueira | 25 May 2021 | 01:08:36 | |
Guests:
Dr. Judy Lieberman is a Professor of Pediatrics at Harvard Medical School and holds an Endowed Chair in Cellular and Molecular Medicine at Boston Children’s Hospital. Dr. Caroline Junqueira is an Investigator at the Oswaldo Cruz Foundation and a visiting scientist at Harvard Medical School. Their recent research focuses on the role of γδ T cells in malaria. Featured Products and Resources:
How Viruses Cause Pyroptosis – Bcl-2 members MCL-1 and BCL-xL sense translation inhibition during viral infection, leading to Gasdermin E-dependent pyroptosis. Aging the Immune System – Researchers selectively deleted Ercc1, which encodes a crucial DNA repair protein, to increase senescence in the immune systems of mice, leading to systemic aging. Thymic Development of Microbiota-Specific T Cells – Scientists showed that intestinal colonization in early life leads to the trafficking of microbial antigens from the intestine to the thymus by intestinal dendritic cells, which then induce the expansion of microbiota-specific T cells. Antibody-Dependent Inflammation in COVID-19 – Researchers found that in patients with severe COVID-19, high titers and low fucosylation of anti-spike IgG leads to excessive inflammatory responses by alveolar macrophages. Photo Reference: Courtesy of Drs. Judy Lieberman and Caroline Junqueira
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| Ep. 4: “Therapeutic T Cell Engineering” Featuring Drs. Carl June and Philipp Rommel | 11 May 2021 | 01:13:35 | |
Guests:
Dr. Carl June is the Richard W. Vague Professor in Immunology at the University of Pennsylvania, Director of the Center for Cellular Immunotherapies at the Perelman School of Medicine, and Director of the Parker Institute for Cancer Immunotherapy. Dr. Philipp Rommel is a Postdoctoral Researcher in the June lab. Together, they are interested in lymphocyte biology, with a major translational focus on ex vivo T cell engineering for cancer and HIV cell-based therapies. Featured Products and Resources: The Immunology Science Round UpPooled CRISPR Screening Identifies m6A RNA as a Regulator of Macrophage Activation – Scientists identified METTL3-mediated m6A modification in innate immune responses suggesting the m6A machinery could be a target for immunotherapy. Natural Killer Receptors Fine-Tune T Cells – Researchers identified a role for natural killer cell receptor signaling in regulating self/non-self discrimination by HLA-E–restricted T cells. Notch4 Signaling in Viral Infections – Notch4 expression on Treg cells suppressed the induction of amphiregulin and promoted severe lung inflammation in viral infections. Synthetic Notch CAR T Cells Targeting Solid Tumors in Mice – Scientists developed synthetic Notch CAR T cells targeting solid tumor antigens and used them to treat mouse models of mesothelioma, ovarian cancer, and glioblastoma. Photo Reference: Courtesy of Drs. Carl June and Philipp Rommel
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| Ep. 3: “Platelets and the Immune System” Featuring Dr. Bernardo Franklin | 27 Apr 2021 | 01:22:22 | |
Guest:
Dr. Bernardo Franklin is a Professor at the University of Bonn. His lab studies the role of innate immunity in sterile inflammation and in infectious diseases. More recently, their research has focused on blood platelets and their effects on innate immunity, systemic inflammation and cancer. Featured Products and Resources:
T Cell Mediated Cross-Reactivity between Seasonal Coronaviruses and SARS-CoV-2 – Researchers found that CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses. COVID-19 Recovered Individuals May Only Require a Single mRNA Vaccine Dose – In individuals who have already recovered from COVID-19, a single mRNA vaccine dose was sufficient to achieve peak antibody and memory B cell responses. Forcing Cancer Out of “Stealth Mode” – DNA methyl transferase inhibitors alter the surface proteome and mediate cytoskeletal reorganization, priming γδ T cells to kill lung cancer cells. Maternal Treg Cells Can Reverse Behavioral Abnormalities in Adult Mouse Offspring – Behavioral abnormalities caused by maternal immune activation could be rescued by transferring pathogen-activated maternal Treg cells. Photo Reference: Courtesy of Dr. Bernardo Franklin
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| Ep. 2: “A Tale of Three Sisters” Featuring Drs. Mindy, Amy, and Kristen Engevik | 13 Apr 2021 | 01:13:06 | |
Guests:
Drs. Mindy, Amy, and Kristen Engevik are sisters and immunologists. Dr. Mindy Engevik is an Assistant Professor at the Medical University of South Carolina. Her lab studies microbial-host crosstalk with an emphasis on microbe-mucus interactions. Dr. Amy Engevik is also an Assistant Professor at the Medical University of South Carolina. Her lab focuses on the role of Myosin Vb in the pathogenesis of gastrointestinal disorders and liver cholestasis. Dr. Kristen Engevik is a postdoctoral fellow at Baylor College of Medicine. Her research aims to elucidate the molecular consequences of purinergic signaling in gastrointestinal physiology and rotavirus pathophysiology, with the ultimate goal of providing further insight to improve vaccines against rotavirus. Featured Products and Resources:
Chronic Immune Response in Severe COVID-19 Does Not Target SARS-CoV-2 – Researchers found that in patients with severe COVID-19, TGF-β is a key regulator of the chronic immune response, and in prolonged cases, this response is no longer directed at SARS-CoV-2. Regulatory T Cells in Tumors and Tissues – Scientists performed single-cell chromatin accessibility profiling of tissue-resident and circulatory regulatory T (Treg) cells, and showed that several surface proteins that were thought to be tumor-specific were also expressed in Treg cells in normal tissue. Mapping the Immune Landscape in Glioblastomas – Researchers used single-cell profiling to study the glioblastoma immune landscape and found that microglia-derived tumor-associated macrophages (TAMs) dominated in newly diagnosed tumors, but were outnumbered by monocyte-derived TAMs following recurrence. T Cells Persist in Melanoma Patients Who Respond Well to Immunotherapy – In metastatic melanoma survivors with exceptional responses to immunotherapy, scientists found T cell clonotypes from tumors in skin and blood up to nine years later. Photo Reference: Courtesy of Drs. Mindy, Amy, and Kristen Engevik
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| Ep. 1: “Merging Stem Cells with Immunology” Featuring Dr. Filipe Pereira | 30 Mar 2021 | 00:58:58 | |
Guest:
Dr. Filipe Pereira is an Associate Professor at the Lund Stem Cell Center at Lund University. The Pereira lab studies how hematopoietic cell fate is specified, maintained, and eventually modified or reversed. Inspired by the fields of stem cell biology, immunology, and cancer, they use an interdisciplinary approach to mechanistically understand hematopoietic and immune cell identities and translate their findings into novel gene and cell therapies. Featured Products and Resources:
Resident T Cells Stay at Home – Researchers examined how immunity is integrated within adult mouse tissues and observed durable maintenance of resident memory T cells up to 450 days after infection. Bacteria-Derived Peptides Found inside Tumors – Scientists identified a peptide repertoire derived from intracellular bacteria that was presented on HLA-I and HLA-II molecules in melanoma tumors. Gamma Delta T Cells Link Immunity to Nutrition – Researchers analyzed mice fed a high-carbohydrate versus a high-protein diet and observed remodeling of the small intestinal epithelium in response to dietary carbohydrates. Neutrophil Extracellular Traps (NETs) Activate Innate Immune Sensor cGAS – In mice, NETs stimulated interferon production in a cGAS-dependent manner, suggesting that cGAS acts as a sensor of NETs to stimulate immune responses during infection. Photo Reference: Courtesy of Dr. Filipe Pereira https://www.stemcellsciencenews.com/neural-cell-news/?utm_source=impodcast&utm_medium=banner https://www.stemcell.com/forms/wallchart-immune-cytokines.html?utm_source=impodcast&utm_medium=banner Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| The Immunology Podcast Is Launching in March 2021 | 12 Feb 2021 | 00:00:39 | |
In March of 2021, the Immunology Podcast will be launching with the goal of creating an accessible, entertaining, and educational resource for scientists to keep current on the latest developments in immunology research. The hosts, Drs. Brenda Raud and Jason Goldsmith, will cover the latest scientific advances and interview key immunology influencers about their work and perspectives on the field. The Immunology Podcast is owned and produced by STEMCELL Technologies, a global biotechnology company based out of Vancouver, Canada. STEMCELL provides the podcast under their Science Communication Program, alongside several other services to keep scientists current and connected with their fields. This includes the Stem Cell Podcast, which covers groundbreaking research in the field of stem cell biology, and has amassed a global following, with more than 600,000 downloads to date. STEMCELL Technologies supports life sciences research with more than 2,500 specialized cell culture media, cell separation tools, instruments, accessory products and educational services that are used by scientists performing immunology, stem cell, cancer, regenerative medicine, and cellular therapy research globally. Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2024™: Day 4 | 07 May 2024 | 00:14:06 | |
In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the fourth of five special episodes from the meeting, where Brenda and Jason highlight discussions on tumor-infiltrating lymphocyte therapy, chaired by former podcast guest Dr. Kristin Anderson, as well as fueling T cell fate decision during infection with an initial focus on immunometabolism. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2024™: Day 3 | 06 May 2024 | 00:22:29 | |
In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Brenda and Jason spotlight discussions on cellular responses of microbial and parasitic infection and the immunology of pregnancy with a focus on glycan regulation of fetomaternal tolerance. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2024™: Day 2 | 05 May 2024 | 00:25:44 | |
In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Brenda and Jason discuss highlights from sessions including microbial and environmental influences on the gut and recent breakthroughs in emerging therapeutic strategies for chronic inflammatory and fibrotic diseases. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2024™: Day 1 | 04 May 2024 | 00:20:36 | |
In May 2024, we attended IMMUNOLOGY2024, the annual meeting of the American Association of Immunologists in Chicago, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting, in which Jason and Brenda highlight sessions on innate and innate-like cells and transplant immunology. Discussions include the role of hypothermia in protecting ventilator-induced lung damage and Siglec-E knockout in transplant rejection. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 77: “Computational and Translational Immunology” Featuring Dr. Caleb Lareau | 23 Apr 2024 | 01:18:11 | |
Guest:
Dr. Caleb Lareau is an Assistant Professor at Memorial Sloan Kettering Cancer Center. His lab aims to understand how cells in our bodies adapt, expand, and evolve during the course of our lives, particularly in the immune system. He talks about cross-training in bioinformatics and immunology, and herpesvirus reactivation in CAR T cells. Featured Products and Resources:
Blocking Lung Injury in Influenza – Scientists developed an inhibitor to block necroptosis in severe influenza infections. Germinal Center Memory B Cells – IL-4 signaling can regulate memory B cell selection. Intestinal Barrier Defence – Citrobacter rodentium targets a subset of absorptive intestinal epithelial cells in the mid–distal colon, which stimulate T cells to produce sustained IL-22 signals to mitigate further spread of the pathogen. Fast-Acting Glucocorticoids – The anti-inflammatory properties of glucocorticoids involve reprogramming of the mitochondrial metabolism of macrophages. Image courtesy of Dr. Caleb Lareau Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 76: “Innate-Like T Lymphocytes” Featuring Dr. Mitchell Kronenberg | 09 Apr 2024 | 01:08:07 | |
Guest:
Dr. Mitchell Kronenberg is a Professor and President Emeritus at La Jolla Institute for Immunology. His lab studies how innate-like T cells adapt to different tissue environments. He talks about his work on MAIT cells and mucosal immunology, as well as his time leading the Institute. Featured Products and Resources:
Immune System Regeneration – Depleting myeloid-biased HSCs in aged mice restores features of a more youthful immune system. Gasdermin in Pyroptosis – Gasdermin D N-terminal domain palmitoylation controls gasdermin membrane localization and activation. Antibody-Drug Conjugates for Cancer – Scientists developed an antibody–drug conjugate that could kill TRBC1+ cancer cells in vitro and cure human T cell cancers in mouse models. Hemorrhagic Fever Cell Receptors – The low density lipoprotein receptor is critical for the Crimean–Congo hemorrhagic fever virus to enter host cells. Image courtesy of Dr. Mitchell Kronenberg Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 75: “Autoinflammatory Diseases” Featuring Dr. Scott Canna | 26 Mar 2024 | 01:10:26 | |
Guest:
Dr. Scott Canna is an Associate Professor of Pediatrics (Rheumatology), and Attending Physician, Pediatric Rheumatology and Immune Dysregulation at the Children’s Hospital of Philadelphia. His group studies the mechanisms of immune dysregulation. He talks about auto- and hyperinflammatory diseases and the role of IL-18. He also discusses hemophagocytic lymphohistiocytosis and adapting therapies for children. Featured Products and Resources:
Microbial Metabolites in Infectious Diseases – Dietary tryptophan protects against gastrointestinal infection by activating the neurotransmitter receptor dopamine receptor D2. T Cell Tolerance – Scientists used neural networks and hybrid mice to see how the transcription factor AIRE recognizes gene promoters. Microbes in Immunotherapy – Lactobacillus johnsonii promotes the production of indole-3-propionic acid, which improves immune checkpoint blockade responsiveness. Alzheimer’s Disease Microglia – Research suggests a link between genetic risk factors for Alzheimer’s disease and microglial lipid droplet accumulation. Image courtesy of Dr. Scott Canna Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 74: “Dengue Pathogenesis” Featuring Dr. Neelika Malavige | 12 Mar 2024 | 01:11:50 | |
Guest:
Dr. Neelika Malavige is the Head of Dengue Global Program and Scientific Affairs at the Drugs for Neglected Diseases Initiative and a Professor in the Department of Immunology and Molecular Medicine at the University of Sri Jayewardenepura. Her research focuses on dengue: its pathogenesis, vascular leak, immune correlates of protection, and biomarkers. She talks about the disease burden of dengue and her investigations into risk factors for severe disease. She also discusses her research on COVID-19 vaccines and the role of the microbiome in colon cancer, as well as how she’s working to grow research capabilities in Sri Lanka. Featured Products and Resources:
SOX17 in Colorectal Cancer – Scientists used AKP organoids to demonstrate that SOX17 orchestrates immune evasion in the early steps of colon cancer. Tregs in Tumor Immunity – Lactate uptake by Treg cells contributes to the efficacy of CTLA-4 blockade. Astrocytes in Autoimmunity – Researchers identified astrocyte-derived heparin-binding EGF-like growth factor as a potential therapeutic target in multiple sclerosis. αβ T Cell Development – By studying patients with pre-TCRα deficiency, scientists found that pre-TCRα may not be absolutely required for αβ T cell development in humans. Image courtesy of Dr. Neelika Malavige Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 73: “T Cell Receptors” Featuring Dr. James Allison | 27 Feb 2024 | 01:21:47 | |
Guest:
Dr. James Allison is the Regental Professor and Chair of the Department of Immunology, Olga Keith Wiess Distinguished University Chair for Cancer Research, Director of the Parker Institute for Cancer Research, Executive Director of the Immunotherapy Platform, and Director of the James P. Allison Institute at MD Anderson Cancer Center. Dr. Allison has spent a distinguished career studying the regulation of T cell responses and developing strategies for cancer immunotherapy. He earned the 2018 Nobel Prize in Physiology or Medicine, which he shared with Dr. Tasuku Honjo, “for their discovery of cancer therapy by inhibition of negative immune regulation.” His current work seeks to improve immune checkpoint blockade therapies currently used by clinicians and identify new targets to unleash the immune system in order to eradicate cancer. He talks about the hunt for the T cell receptor and working to bring CTLA-4 blockade into the clinic. He also discusses what’s next for immunotherapy, including future investigations into myeloid cells, and playing the harmonica in a band. Featured Products and Resources:
Overcoming Antibacterial Resistance – A new antibiotic targets multi-drug-resistant bacteria by binding to ribosomes. Tregs in Visceral Adipose Tissue – Visceral adipose tissue harbors two distinct Treg cell populations: one enriched in males and one enriched in females. How IL-23 Fuels Tumor Growth – A subset of Tregs are responsible for the tumor-promoting effect of IL-23. Smoking and the Immune System – Smoking affects adaptive immune responses for years after quitting. Image courtesy of Dr. James Allison Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 84: “T Cells in Inflammation and Cancer” Featuring Dr. Jeffrey Rathmell | 30 Jul 2024 | 01:07:17 | |
Guest:
Dr. Jeffrey Rathmell is the Cornelius Vanderbilt Professor of Immunobiology at the Vanderbilt Center for Immunobiology. His research focuses on T cell metabolism in cancer. He talks about what T cells use for fuel and his work on fatty acid synthesis. He also discusses the ‘obesity paradox’ in cancer immunotherapy and his favorite parts of being a scientist and professor. Featured Products and Resources:
A Humanized Mouse Model – A new humanized mouse mounts specific and mature antibody and autoantibody responses. IL-11 Signaling in Aging – Inhibiting IL-11 extends the healthspan and lifespan of mice. Sphinganine Synthesis in Macrophages – Sphinganine biosynthesis is a checkpoint for macrophage pattern recognition in mouse models of sepsis and melanoma. Brain-Muscle Signaling – Researchers identified a brain-to-muscle signaling axis in Drosophila that regulates muscle performance. Image courtesy of Dr. Jeffrey Rathmell Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 72: “IMMUNOLOGY2024™: Innovations in Immunology” Featuring Dr. Akiko Iwasaki, Francisco Gomez-Rivera, and Dr. Jason Augustine | 13 Feb 2024 | 01:05:28 | |
Guests:
Dr. Akiko Iwasaki is the Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale University and President of the American Association of Immunologists. Francisco Gomez-Rivera is an Immunology Program Graduate Student Candidate at the University of Michigan, and Dr. Jason (Swinburne) Augustine is a retired Research Microbiologist/Immunologist at the US Environmental Protection Agency. They talk about the upcoming IMMUNOLOGY2024 meeting in Chicago, Illinois from May 3-7, 2024. They discuss key sessions to attend, what they’re looking forward to at the meeting, and advice for attendees. Featured Products and Resources: The Immunology Science Round UpBacteria in Gastric Cancer – Streptococcus anginosus promotes gastric tumorigenesis via direct interactions with gastric epithelial cells. CAR T Cells for Aging – Senolytic CAR T cells safely eliminate senescent cells in young animals. Microbiota and Tuft Cell Biology – Microbiota calibrate type 2 immunity in the intestine by controlling tuft cell differentiation. Sex Differences in Autoimmunity – Autoantibodies to the Xist ribonucleoprotein characterize female-biased autoimmune diseases. Images courtesy of Dr. Akiko Iwasaki, Robert Lisak, Francisco Gomez-Rivera, and Dr. Jason (Swinburne) Augustine Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 71: “The Neuroscience of HIV” Featuring Dr. Dionna Williams | 30 Jan 2024 | 01:02:51 | |
Guest:
Dr. Dionna Williams is an Acting Associate Professor in the Department of Pharmacology & Chemical Biology at Emory University. Their research focuses on the effects of HIV infection on the brain. She talks about how HIV affects immune cells in the brain and how this can lead to neuropsychiatric symptoms. They also discuss therapeutic approaches, factors that affect how drugs can reach the brain, and moving their lab to Atlanta. Featured Products and Resources:
A Long Covid Blood Signature – Active Long Covid is accompanied by a blood protein signature marked by increased complement activation and thromboinflammation. T Cells in Guillain–Barré Syndrome –Autoreactive T cells that target myelin antigens in the peripheral nerves are present in patients with the demyelinating form of Guillain–Barré syndrome. A CAR-NK Cell Clinical Trial – Researchers identified features of donated cord blood associated with improved response to CAR-NK cell therapy for B cell malignancies. Cas9-Packaging Enveloped Delivery Vehicles – Researchers developed an antibody-directed strategy for delivering genome engineering tools to specific cell types. Image courtesy of Dr. Dionna Williams Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 70: “Public Outreach” Featuring Drs. Akiko Iwasaki and Aimee Bernard | 16 Jan 2024 | 01:04:39 | |
Guests:
Dr. Akiko Iwasaki is the Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale University and President of the American Association of Immunologists (AAI), and Dr. Aimee Bernard is an Assistant Professor of Immunology and Microbiology at the University of Colorado. Dr. Iwasaki has a very active presence on X, where she shares about COVID-19 research. Dr. Bernard is also active on social media through her TikTok account, and co-hosts a podcast, Help! Make It Make Sense. In this episode, they discuss the importance of communicating science to the public and strategies for social media. They also talk about how the AAI is working to share immunology knowledge with non-scientists through Immunology Explained. Featured Products and Resources:
A New Antibiotic for Gram-Negative Bacteria – A mechanism of lipid transport inhibition has been identified for a class of peptide antibiotics effective against resistant Acinetobacter strains. Treg Depletion As Cancer Treatment – Researchers examined the mechanism of Treg cell depletion failure using a mouse model of Treg cell–targeted immunotherapy. Immunotherapy Resistance in Melanoma – Using single-cell, spatial multi-omics, scientists showed that the tumor microenvironment promotes the emergence of a complex melanoma transcriptomic landscape. An Immune Dictionary of Cytokine Responses – Scientists created single-cell transcriptomic profiles of more than 17 immune cell types in response to each of 86 cytokines in mouse lymph nodes in vivo. Images courtesy of Robert Lisak, YSM and Dr. Aimee Bernard Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 69: IUIS 2023: On the Ground | 19 Dec 2023 | 01:07:03 | |
In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies (IUIS), in Cape Town, South Africa. We spoke with delegates about their research and impressions of the meeting, including their reasons for attending and the most memorable research presented. They discuss their experiences in South Africa, the meeting’s focus on infectious diseases and equitable science, and sessions by Nobel laureates. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 68: “Blood Transfusions” Featuring Dr. David Gibb | 05 Dec 2023 | 01:11:53 | |
Guest:
Dr. David Gibb is an Assistant Professor at Cedars-Sinai Medical Center. His lab investigates inflammatory mechanisms in patients with sickle cell disease and lupus, focusing on mechanisms regulating immune responses to red blood cell antigens following transfusion. Featured Products and Resources:
Regulation of Lymphoid Cells – NOD1 functions in murine hematopoietic cells as a major regulator of both the generation and differentiation of lymphoid progenitors. The Aging Immune System – Type 2 memory CD4+ and CD8+ T cells increase with age and can produce more IL-4. Microglia in Cancer Metastasis – Microglia play a distinct pro-inflammatory and tumor-suppressive role in breast cancer brain metastasis. MAIT Cells in Mice and Humans – Environment influences MAIT cell development and function. Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IUIS 2023: Day 5 | 03 Dec 2023 | 00:20:34 | |
In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the final of five special episodes from the meeting, in which Brenda and Jason discuss sessions on integrins and ebola vaccine trials. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IUIS 2023: Day 4 | 01 Dec 2023 | 00:20:16 | |
In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the fourth of five special episodes from the meeting, in which Brenda and Jason discuss sessions on the HIV/AIDS epidemic and vaccination strategies to prepare for the next pandemic. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IUIS 2023: Day 3 | 01 Dec 2023 | 00:24:47 | |
In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the third of five special episodes from the meeting, in which Brenda and Jason discuss research on T cell exhaustion in chronic infections and sex differences in immune responses. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IUIS 2023: Day 2 | 29 Nov 2023 | 00:21:01 | |
In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the second of five special episodes from the meeting, in which Brenda and Jason discuss research on the microbiome, sepsis, and the aging immune system. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IUIS 2023: Day 1 | 29 Nov 2023 | 00:30:05 | |
In 2023, we attended the 18th International Congress of Immunology, hosted by the International Union of Immunological Societies, in Cape Town, South Africa, and recorded daily episodes discussing highlights of the conference. Here is the first of five special episodes from the meeting, in which Brenda and Jason discuss the opening ceremony of the congress as well as sessions on tuberculosis, γδ T cell receptors, and cancer immunotherapy. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 83: “Biomolecular Sensors” Featuring Dr. Shana Kelley | 16 Jul 2024 | 01:09:35 | |
Guest:
Dr. Shana Kelley is the President of the Chan Zuckerberg Biohub Chicago and the Neena B. Schwartz Professor of Chemistry and Biomedical Engineering at Northwestern University. The Kelley research group works in a variety of areas spanning bio analytical technology development and has pioneered new methods for tracking molecular and cellular analytes with unprecedented sensitivity. She talks about developing DNA-based reagentless biosensors and commercializing new technologies. Featured Products and Resources:
Tuberculosis Target Structure – Cryogenic electron microscopy structures of Mycobacterium tuberculosis ATP synthase sheds light on drug binding. Toll-Like Receptor Signaling – Researchers engineered macrophages to delineate TLR pathway activities. Onco-Fetal Immune Tolerance – Scientists cross-analyzed single-cell RNA sequencing data from human cancer types and the maternal-fetal interface to identify an onco-fetal immune tolerance checkpoint. Tau Immunotherapy – Scientists loaded tau antibodies into micelles and administered them intranasally in mice. Image courtesy of Dr. Shana Kelley Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 67: “Vascular and Immune Aging” Featuring Dr. Anjali Kusumbe | 21 Nov 2023 | 01:00:44 | |
Guest:
Dr. Anjali Kusumbe is a Group Leader and Director of the Tissue Imaging Centre at Oxford University. Her lab studies vascular changes over time with the aim of treating diseases. She talks about light sheet microscopy techniques, the aging immune system, and finding lymphatic vessels in bone. Featured Products and Resources: The Immunology Science Round UpHerpesvirus in CAR T Cell Therapy – A population of ‘super-expressor’ CAR T cells can contribute to the reactivation of latent human herpesvirus 6. Autoantibodies in NF-κB2 Deficiency – Inborn errors of the alternative NF-κB pathway underlie the production of autoantibodies against type I interferons and predisposition to viral diseases. A Rheumatoid Arthritis Atlas – Scientists built a single-cell atlas of rheumatoid arthritis synovial tissue. Tregs After Exercise – Researchers identified Tregs as a key regulatory element that is activated in response to exercise and needed to support muscle adaptations. Image courtesy of Dr. Anjali Kusumbe Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 66: “Immune Cell Interactions” Featuring Dr. Sophia Liu | 07 Nov 2023 | 01:05:40 | |
Guest:
Dr. Sophia Liu is a Core Faculty Member and Early Independence Fellow at the Ragon Institute of Mass General, MIT, and Harvard. She enjoys creating new ways to measure temporally and spatially dynamic cell interactions and is particularly interested in studying T- and B-cell development. Her lab’s research focuses on immune cell interactions in tissues and dynamics across immune development and aging. She talks about the spatial mapping of T-cell receptors, what happens to the thymus during aging, and her experience starting a lab straight out of her PhD! Featured Products and Resources: The Immunology Science Round UpA Functional Coronavirus Receptor – Scientists identified a functional receptor for a coronavirus that causes the common cold. Counting Immune Cells in the Human Body – An average individual’s immune system consists of approximately 1.8 trillion cells. Gut Bacteria in Type 1 Diabetes – IgG2 antibodies against three gut microbial commensals are associated with time to diagnosis and clinical response to T cell-directed therapy for type 1 diabetes prevention. Lymph Node Immune History – Tregs can form resident memory-like populations in lymph nodes after adaptive immune responses. Image courtesy of Dr. Sophia Liu Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 65: “Primary Immunodeficiency Disorders” Featuring Dr. Siobhan Burns | 24 Oct 2023 | 01:01:30 | |
Guest:
Dr. Siobhan Burns is a Professor of Translational Immunology at University College London. Her group studies the underlying molecular and cellular mechanisms that give rise to primary immunodeficiency disorders. She talks about how genetic mutations affect immune function, and what inborn errors of immunity can teach us about general immunology. Featured Products and Resources: The Immunology Science Round UpA Cryptic Antigen in Influenza – Researchers identified a nonclassical MHC epitope that directs the T cell response against influenza. Drug-Resistant Malaria Parasites – Scientists generated atovaquone-resistant malaria parasites and showed that they fail to transmit by mosquito. Transplanting Genetically Modified Pig Kidneys into Monkeys – Scientists showed that preclinical studies of renal xenotransplantation could be successfully conducted in nonhuman primates. Dendritic Cells to Reduce Immunosuppression After Liver Transplant – Liver transplant recipients who receive regulatory dendritic cells may require less immunosuppressive drugs. Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 64: “Brain Tumor Immunotherapy” Featuring Dr. Peter Fecci | 10 Oct 2023 | 01:07:43 | |
Guest:
Dr. Peter Fecci is a Professor of Neurosurgery at Duke University and the Director of the Duke Center for Brain and Spine Metastasis. His research focuses on brain tumor immunology and immunotherapy, and T cell dysfunction in glioblastoma and other intracranial cancers. He talks about activating T cells to target brain tumors and his team’s work on targeting MHC-I-negative tumor cells. Featured Products and Resources:
A Universal Flu Vaccine Candidate – A group 2 hemagglutinin universal influenza virus vaccine candidate protects mice against group 2 influenza viruses. Regulatory T Cells in Muscle Function – Exercise induces a highly functional and stable muscle Treg phenotype. An Antiviral Drug and SARS-CoV-2 Mutations – Scientists identified a mutational spectrum from viruses in patients treated with molnupiravir. Microbial Exposure and Allergic Inflammation – Increased microbial biodiversity in mice does not protect against allergic inflammation, in contrast to what would be predicted by the hygiene hypothesis. Image courtesy of Dr. Peter Fecci Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 63: “T Cell Tolerance” with Dr. Alice Long | 26 Sep 2023 | 01:00:18 | |
Guest:
Dr. Alice Long is an Associate Member and Principal Investigator at Benaroya Research Institute at Virginia Mason, where her lab focuses on discovering how tolerance is lost in human autoimmunity and how therapy can restore tolerance. Featured Products and Resources:
Insights into B Cell Selection – Antigen-presenting autoreactive B cells play a crucial role in tolerizing T cells and suppressing tissue-specific autoimmune inflammation. A New Perspective for IBD Management – Researchers discovered a polymorphism encoding a defective fusion protein that is correlated with inflammatory bowel disease severity. A Neuropeptide in Type 2 Immunity – Scientists show that neuromedin U programs eosinophils to promote mucosal immunity of the small intestine. Intestinal Antigen Recognition and Humoral Immunity – A new study shows that antigen receptor signaling and cell death resistance control intestinal humoral response zonation. Image courtesy of Alice Long Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 62: “T Cells in Solid Tumors” Featuring Dr. Kristin Anderson | 12 Sep 2023 | 01:09:50 | |
Guest:
Dr. Kristin Anderson is an Assistant Professor at the University of Virginia, where her lab focuses on engineering T cells to overcome immune suppression in the tumor microenvironment. She talks about how her cancer diagnosis changed her career focus, strategies for targeting ovarian cancer, and her transition from postdoc to professor. Featured Products and Resources:
Antibiotic Binding Site Mutations – Researchers studied the rifampicin binding site of E. coli RNA polymerase. CRISPR Screens for Cancer – Scientists combined genome-wide CRISPR screens in target cancer cells to identify pathways that regulate γδ T cell killing and BTN3A cell surface expression. Tissue-Resident T Cell Metabolism – Researchers explored the metabolic adaptations supporting differentiation, survival, and function of tissue-resident memory CD8+ T cells. Towards a Universal CAR T Cell Therapy for Blood Cancers – Epitope-edited CAR T cells were effective against patient-derived acute myeloid leukemia, B cell lymphoma, and acute T cell leukemia. Image courtesy of Dr. Kristin Anderson Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 61: “Pancreatic Cancer” Featuring Dr. Vinod Balachandran | 29 Aug 2023 | 01:07:39 | |
Guest:
Dr. Vinod Blachandran is an Attending Surgeon and Lab Head at Memorial Sloan Kettering Cancer Center. He talks about neoantigen vaccines for pancreatic cancer, what can be learned from a rare group of long-term survivors, and how surgeon-scientist mentors have influenced his career. Featured Products and Resources: The Immunology Science Round UpPlatelet Factors in Aging – Platelet factors transfer the benefits of young blood to the aging mouse brain. Cellular Immunity in Influenza – Adaptive T cells protect against symptomatic influenza infection. Interactions Between the Immune System and the Gut Microbiome – T cells in the gut repertoire recognize several bacterial strains from complex defined communities. Aryl Hydrocarbon Receptor Signaling in Lung Endothelial Cells – Aryl hydrocarbon receptor and its ligands play an important part in protecting against tissue damage following viral pathogen infection in the lung. Image courtesy of Dr. Vinod Balachandran Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 60: “Immunometabolism and Cancer Immunotherapy” Featuring Dr. Greg Delgoffe | 15 Aug 2023 | 01:14:02 | |
Guest:
Dr. Greg Delgoffe is an Associate Professor at the University of Pittsburgh. His lab studies the intersection of metabolism and immunity in cancer. He talks about the metabolism of immune cells in cancer and the effects of nutrients in the tumor microenvironment. Featured Products and Resources: The Immunology Science Round UpMicrobes in Diabetes Drug Responses – Researchers identified a microbiota-derived enzyme as a potential antidiabetic target. STING Can Transport Protons – Scientists analyzed STING’s structure, hypothesizing that its transmembrane domain forms a pore capable of proton transport. cGAS–STING in Neurodegeneration – The cGAS–STING signaling pathway is a critical driver of chronic inflammation and functional decline during aging. T Cells Can Kill MHC-I Negative Tumor Cells – CD8+ T cells maintain the capacity to kill tumor cells that are entirely devoid of MHC-I expression. Image courtesy of Dr. Greg Delgoffe Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 59: “Infectious Disease Ecology and Evolution” Featuring Dr. Daniel Streicker | 01 Aug 2023 | 01:01:05 | |
Guest:
Dr. Daniel Streicker is a Professor of Viral Ecology at the University of Glasgow, where his lab investigates pathogen transmission between species. He talks about vampire bats as a reservoir for rabies and approaches to vaccination that could prevent transmission. Featured Products and Resources:
Sleep Disturbance in Cardiac Disease – Sleep disruption in cardiac disease is driven by the loss of neurons that normally project from the superior cervical ganglia into the pineal gland. Influenza Vaccine Format and Antibody Responses – Using a human tonsil organoid model, researchers tracked the differentiation and kinetics of the adaptive immune response to influenza vaccine and virus modalities. Multipronged T Cells – Single T cells from successful immunotherapy recognize multiple cancer types. γδ T Cells in Solid Tumors – Tumor-infiltrating γδ T cells consist of functionally distinct subsets with tumor-promoting or -restricting functions. Image courtesy of Dr. Daniel Streicker Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 58: “Redesigning Proteins” Featuring Dr. Jamie Spangler | 18 Jul 2023 | 01:09:52 | |
Guest:
Dr. Jamie Spangler is an Assistant Professor at Johns Hopkins. Her lab implements a unique structure-based engineering approach to elucidate the determinants of protein activity and inform drug development. She talks about designing cytokine mimetics and how engineered cytokines could be used as therapeutics. Featured Products and Resources:
Microenvironment Reprogramming in Cancer Progression – Researchers developed a high-resolution tumor microenvironment atlas for gastric adenocarcinoma. Tregs and Cell Therapy for Parkinson’s Disease – Co-transplanting Tregs with iPSC-derived neurons improves cell survival. How Hepatitis C Hides from the Immune System – Flavin adenine dinucleotide capping of the hepatitis C virus protects RNA from RIG-I mediated innate immune recognition. Mast Cells in Antigen-Avoidance – Mast cell activation in the stomach lining releases leukotrienes to affect food avoidance behavior. Allergic Responses and Behavior Modification – Researchers showed that allergic sensitization drives antigen-specific avoidance behavior in mouse models of food allergy. Image courtesy of Dr. Jamie Spangler Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 82: “Immunological Memory” Featuring Dr. Susan Kaech | 02 Jul 2024 | 01:15:14 | |
Guest:
Dr. Susan Kaech is a Professor and Director of the NOMIS Center for Immunobiology and Microbial Pathogenesis at the Salk Institute. Her lab aims to understand how memory T cells are produced during infection and vaccination, how they function, and why they can fail to induce long-term immunity, particularly during chronic disease or cancer. In this episode, she talks about her research on T cell exhaustion and neuroimmunology, as well as her path from genetics to immunology. Featured Products and Resources:
Glycan Breakdown and Bacterial Function – Researchers used a large-scale screen to identify enzyme systems that represent an underappreciated mode of glycan degradation. Cancer Risk after CAR T Therapy – Only a small percentage of patients who receive CAR T therapies develop secondary cancers, and most are not directly linked to CAR T treatment. CD8+ T Cells in Hepatitis B – Hepatocellular priming induces key co-signaling receptors in dysfunctional CD8+ T cells. T Cell Aging – T cell epigenetic clocks measure replicative history and can continue to accumulate well-beyond organismal lifespan. Image courtesy of Dr. Susan Kaech Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 57: “Careers Away from the Bench” Featuring Drs. Laura Raff and Ami Ashar-Patel | 04 Jul 2023 | 00:59:44 | |
Guests:
Dr. Laura Raff is Associate Director, Sales, Immunology and Dr. Ami Ashar-Patel is a Senior Account Manager, Immunology at STEMCELL Technologies. Dr. Raff has a PhD in Molecular Microbiology and Immunology from the University of Southern California and Dr. Ashar-Patel has a PhD in Biochemistry and Molecular Pharmacology from the University of Massachusetts Chan Medical School. They talk about their career transitions from academia to industry and how they support scientists’ research endeavors in their current roles. Featured Products and Resources:
Multiplexed Screening of G-Protein-Coupled Receptors – Scientists screened 1,041 human-associated metabolites against and uncovered previously unreported endogenous, exogenous, and microbial G-protein-coupled receptor agonists. New Oral Polio Vaccines – Genetically engineered polio vaccine candidates reduce the likelihood of Sabin strains regaining fitness and neurovirulence. Fecal Transplants and Immune Checkpoint Inhibition – Fecal microbiota transfer from healthy donors promotes resolution of refractory immune checkpoint-inhibitor mediated colitis in patients with cancer. Macrophages in the Nervous System – Resident macrophages of the muscularis externa refine the enteric nervous system early in life. Images courtesy of STEMCELL Technologies Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| Ep. 56: “Epitopes and the Immune System” Featuring Dr. Alessandro Sette | 20 Jun 2023 | 01:13:37 | |
Guest:
Dr. Alessandro Sette is a Center Head, Division Head, and Professor at the La Jolla Institute of Allergy and Immunology. His lab focuses on understanding the immune response, measuring immune activity, and developing disease intervention strategies against cancer, autoimmunity, allergy, and infectious diseases. He talks about bringing a biotech mindset back to academia, cross-reactive T cell responses to SARS-CoV-2, and compiling an immune-epitope database. Featured Products and Resources:
Gut T Cells and Cancer Metastasis – A subset of CD8+ T cells from colon tumors improves control of liver tumors in a preclinical model of colorectal carcinoma. α2-adrenergic Receptors and Immunotherapy – α2-Adrenergic receptor agonists have very strong anti-tumor activity when used as monotherapies in multiple immunocompetent tumor models. Bacteria in Immune Checkpoint Blockade – Antibiotic-induced changes in gut microbiota resulted in relocation of immunosuppressive T cells from the gut to tumors. Base Editing CAR T Cells – Researchers investigated the safety of base-edited CAR T cells in three children with relapsed leukemia. Image courtesy of Dr. Alessandro Sette Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2023: On the Ground | 06 Jun 2023 | 00:52:42 | |
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists, in Washington, DC. We spoke with delegates about their research and impressions of the meeting, including their reasons for attending, what they were most looking forward to, and the most memorable research presented. Featured Products and Resources:
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| Ep. 54: “Innate and Mucosal Immunity” Featuring Dr. Bana Jabri | 23 May 2023 | 01:06:45 | |
Guest:
Dr. Bana Jabri is the Sarah and Harold Lincoln Thompson Professor in the Department of Medicine and the Research Director of the Celiac Disease Center at the University of Chicago. Her research focuses on innate and mucosal immunity, particularly in celiac disease, autoimmune disorders, and inflammatory bowel disease. She talks about the mechanisms of celiac disease and new treatment options. She also discusses how the microbiome can affect immune responses in cancer. Featured Products and Resources: The Immunology Science Round UpCapsules to Study the Intestinal Environment – Scientists developed an ingestible device that collects samples from multiple regions of the human intestinal tract during digestion. T Cell Receptor Affinity – Repetitive pathogen exposure leads to the dominant outgrowth of T cell clones with high T cell receptor affinity to the relevant pathogen-associated antigens. Gut Bacterial Evolution Between Species – Analyses of metagenome-resolved genomes from humans and primate species reveal significant co-diversification of bacterial gut symbionts. A Pancreatic Cancer Vaccine – Researchers synthesized mRNA neoantigen vaccines in real time from surgically resected pancreatic ductal adenocarcinoma tumors. Image courtesy of Dr. Bana Jabri Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2023: Day 5 | 16 May 2023 | 00:18:48 | |
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the final of five special episodes from the meeting. Brenda and Jason talk about sessions on mucosal immunity, emerging pathogens, and having a successful postdoctoral experience. Highlights include Dr. Isaac Chiu‘s talk on pain and mucus production in the gut, Dr. James Crowe‘s talk on monoclonal antibody discovery, and Dr. Amy Hartman’s talk on Rift Valley fever virus. Featured Products and Resources:
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| IMMUNOLOGY2023: Day 4 | 15 May 2023 | 00:19:15 | |
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the fourth of five special episodes from the meeting. Brenda and Jason talk about micelles for drug delivery and how helminth infection affects susceptibility to SARS-CoV-2. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2023: Day 3 | 14 May 2023 | 00:26:45 | |
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Highlights include Dr. Anthony Fauci’s talk on the COVID-19 pandemic response and Dr. Doug Green’s talk on T cell activation. Jason and Brenda discuss sessions on immune responses in aging and obesity, and making better cancer vaccines. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2023: Day 2 | 13 May 2023 | 00:31:17 | |
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Brenda and Jason discuss sessions on peripheral neuroimmune interactions and tumor cellular therapy. Highlights include the President’s Address by Dr. Mark Davis and Dr. Barbara Rehermann’s presentation on wild mouse microbiota. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||
| IMMUNOLOGY2023: Day 1 | 12 May 2023 | 00:23:47 | |
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting, in which Jason and Brenda summarize symposia on B and T-helper cells, and metabolic and gut microbiota. They discuss antigenic imprinting, lupus immunophenotyping and sex differences, dengue vaccines, and cytomegalovirus research. Featured Products and Resources: Subscribe to our newsletter!Never miss updates about new episodes. Subscribe | |||