The Hormone Solution is a top-ranked women's health podcast focused on perimenopause, menopause, hormone replacement therapy (HRT), weight gain, metabolism, thyroid health, and midlife transformation.
Hosted by Certified Hormone Specialist Karen Martel, this show helps women in their 40s and 50s understand what's really happening with their hormones — and what to do about it.
If you're struggling with perimenopause symptoms, menopause weight gain, estrogen dominance, low progesterone, testosterone decline, brain fog, poor sleep, thyroid dysfunction, or metabolic slowdown, this podcast breaks it down in a clear, practical, no-nonsense way.
Each episode features:
• Evidence-based hormone education
• Expert interviews
• Real-world HRT guidance
• Midlife weight loss strategies
• Thyroid and metabolic health insights
With over 2.5 million downloads and ranked in the Top 30 on iTunes, The Hormone Solution is trusted by women worldwide who want real answers about bioidentical hormones, menopause treatment options, and midlife health.
New episodes every Tuesday and Saturday.
Take the free hormone quiz at karenmartel.com
Shop Midlife Products and Solutions at midlifesolutions.org
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Reverse Dieting, Metabolic Recovery, and the Real Way to Fix Your Fat Loss Plateaus with Philip Pape
Saturday, November 15, 2025 • Duration 01:14:20
Are you struggling with weight loss despite following a strict diet? Ever wondered if eating more could actually help you lose weight? Join us in this episode as we dive into the intriguing world of reverse dieting and metabolic recovery with Philip Pape, a high-performance nutrition coach.
Do you know about GLP-1 medications and their revolutionary role in weight management? Are you curious about how to optimize your metabolism and finally break through those frustrating weight loss plateaus? Philip unpacks these groundbreaking topics, providing you with the knowledge to transform your fitness journey.
With the holiday season fast approaching, how can you maintain your fitness goals amidst the festive chaos? Learn strategic approaches to adapt your workout routines and nutritional habits to ensure success. Get ready to explore the nuances of metabolic recovery and why it might just be the missing piece in your weight loss puzzle.
In this episode, we uncover:
How reverse dieting differs from traditional dieting approaches and its potential benefits.
Why GLP-1 medications are creating a buzz in the fitness industry.
The psychological and physiological aspects of a successful recovery diet.
How to strategically manage your fitness goals during the holiday season.
Why performance blood work is crucial for uncovering hidden health constraints.
Ready to revolutionize your approach to fitness and weight loss? Don't miss this episode packed with expert insights and practical strategies!
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Timeline is offering 20% off your first order of Mitopure. Go to timeline.com/KARENMARTEL and use code HORMONE.
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.
Visit karenmartel.com to explore our comprehensive programs:
Tesofensine: The Next Big Weight Loss Compound That Boosts Dopamine, Burns Fat and Lights up the Midlife Brain
Saturday, November 8, 2025 • Duration 01:04:03
Ready to hear about a new revolutionary weight loss strategy tailored for midlife women? Ever wondered how cutting-edge peptides and hormones can transform your wellness journey? This episode dives deep into the world of tesofensine, a fascinating compound originally researched for Parkinson's and Alzheimer's, now making waves in weight management.
What makes tesofensine a potential game-changer for women experiencing hormonal shifts during perimenopause and menopause? How does it work to enhance neurotransmitter balance and boost metabolic health? Discover the unexpected benefits and potential side effects of this serotonin, noradrenaline, and dopamine reuptake inhibitor.
Let's explore hormone cycling, peptide desensitization, and the science behind sustainable weight loss. How can strategic breaks and cycling enhance the efficacy of weight management strategies? And what role does tesofensine play in this transformative journey? Tune in to uncover these insights and more!
In this episode, we uncover:
How tesofensine is reshaping weight loss for midlife women.
Why neurotransmitter balance is crucial during hormonal shifts.
The science behind tesofensine's dual-action weight loss effects.
How hormone cycling can prevent peptide desensitization.
Why combining tesofensine with 5-HTP offers sustainable results.
Dive into this episode to unlock the secrets of effective weight management for midlife women. Learn how these cutting-edge strategies can enhance your wellness journey and support a balanced lifestyle!
Part 2 The Deepest Hormone Dive Yet: Genetics, Detox & Root Causes of Imbalance & More with Dr. Liz Bartman
Saturday, September 20, 2025 • Duration 54:12
Want to unlock the secrets of hormonal health during menopause? Curious about how hormone replacement therapy interacts with histamine sensitivity? Part 2 of this series with Dr. Liz Bartman dives deep into the relationship between estrogen, progesterone, and histamine, especially for those navigating mast cell activation syndrome.
Have you ever wondered why your menstrual migraines occur? Or how enzymes like diamine oxidase and NQO1 play a pivotal role in managing hormonal balance and oxidative stress? This episode reveals the science behind these complex interactions and how they impact your overall well-being.
What role do genetics play in hormone metabolism? How can a personalized approach using genetic insights and specialized supplements transform your health journey? Join us as we explore these questions, offering fresh perspectives on hormonal wellness.
In this episode, we uncover:
How estrogen hormone replacement therapy affects histamine sensitivity and MCAS.
Why balancing estrogen and progesterone is crucial for minimizing histamine-related symptoms.
How genetic insights can guide personalized hormone management strategies.
The science behind the enzyme NQO1's role in cellular protection and regulation.
Why personalized supplements are key to addressing hormonal imbalances at their root causes.
Check out this enlightening episode filled with expert insights and actionable advice. Discover the path to mastering your hormonal health and thriving during menopause!
Timeline is offering 20% off your first order of Mitopure. Go to timeline.com/HORMONE20 use coupon HORMONE20 and get 20% off your order.
Quick Hits: What the Heck is Happening to My Hormones? Perimenopause to Menopause, What You Need to Know.
Tuesday, October 8, 2024 • Duration 23:24
Welcome to Quick Hits: Blasts from The Past. Join Karen as she explores her podcast archives, offering you short, impactful excerpts from standout episodes. In just 15 minutes, you'll experience the essence of past conversations, packed with valuable insights and memorable moments from our guests. If you want to dive deeper, you'll find links to the full episodes in the show notes below.
Are you in perimenopause? My guess is you don't know. Most women are not informed about what is happening to their hormones in their 30s, 40s and beyond.
Trust me when I say YOU NEED TO KNOW! This is your body and during this time you can be affected in every way mentally, physically, & spiritually.
When you know and understand what is happening to your hormones you can get the help you need to sail through this time with confidence and ease.
Here's what you'll learn:
Understanding Perimenopause and Menopause: Most women aren't informed about when perimenopause starts or what menopause truly is, including the symptoms and tests involved.
Lack of Awareness: Many women don't fully understand what happens during a typical 28-day cycle, let alone during perimenopause and menopause.
Perimenopause Timing: Did you know that perimenopause often begins around age 35? This can come as a surprise, especially for women who are starting families around this time.
Personal Experience: Karen shares her own story of having children at 31 and 37, highlighting the stark differences in recovery and how age can affect your hormones.
Arming Yourself with Knowledge: By understanding what's happening to your hormones, you'll be better equipped when discussing your health with a doctor or doing your own research.
Sponsors: Try the ALIGN Mat today and feel the difference. Coupon code is KAREN5 for $100 off the zen mat or $150 off Stealth mat. embed:
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit to explore our comprehensive programs: Your host: Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert
How This Magic Mat is Revolutionizing Stress Relief, Sleep, and Healing – The PEMF Breakthrough with Alyssa Blue and Mike Mcpherson
Saturday, October 5, 2024 • Duration 01:24:17
Alyssa Blue is a non practicing Aerospace engineering that found the human body more fascinating than rockets. After suffering a health crisis in her early 20's she went on a decade long journey learning how to heal herself. Today as an FDNP, her research background shines, taking a deep dive to investigate her clients bio-individuality and walk with them on a path back to balance. Mike McPherson has a similarly pain to purpose story being an innate medical intuitive and having no resources to understand his extra sensory perceptions, he suppressed his gifts for years, was diagnosed with ADHD and dyslexia as a child. As a young adult he was prescribed medications to cope with severe anxiety and depression. A mentor assisted Mike on a path of discovery into his gifts. Mike now guides others in subconscious trauma patterns back to wholeness through the use of multiple energetic modalities.
Out of a necessity to help more people than their 1-2-1 practice would allow Mike and Alyssa embarked on a 2.5 year journey of R&D to co-create ALIGN, the only Schumann Resonance tuned PEMF Mat on the market. It is a meticulously crafted art piece blending ancient wisdom and modern technology to empower more people heal themselves at home.
Alyssa and Mike are here today to share their inspiring journeys from conventional careers and personal health challenges to the creation of the Align Mat. This unique mat, which incorporates frequency technology and crystals, is designed to harness the Schumann resonance and PEMF for home healing. They discuss how their experiences led them to develop this innovative tool that blends ancient wisdom with modern technology. They emphasize the Align Mat's therapeutic benefits, such as stress relief, improved sleep, and emotional release. We'll hear insights into how these cutting-edge mats can amplify the body's natural healing potential, providing a new perspective on achieving emotional and physical balance.
In this episode:
How the Align Mat utilizes PEMF technology, crystals, and infrared heat for holistic healing.
Why the Align Mat is able to achieve grounding and calming effects.
Quick Hits: The Hormone and Diet Connection to Alzheimer's with Dr. Dale Bredesen
Tuesday, October 1, 2024 • Duration 25:37
Welcome to Quick Hits: Blasts from The Past. Join Karen as she explores her podcast archives, offering you short, impactful excerpts from standout episodes. In just 15 minutes, you'll experience the essence of past conversations, packed with valuable insights and memorable moments from our guests. If you want to dive deeper, you'll find links to the full episodes in the show notes below.
Dr. Bredesen is an internationally recognized expert in the mechanisms of neurodegenerative diseases, Dr. Dale Bredesen's career has been guided by a simple idea that Alzheimer's as we know it is not just preventable, but reversible.
In this episode;
Why every woman needs to be aware of her risks for Alzheimer's as it is a woman's centric disease.
How your diet, hormones and toxic load can contribute to Alzheimer's.
The importance of getting a cognoscopy done in your 40's.
How we can all prevent Alzheimer's and stop its progression.
Why you want to test for the genetic predisposition to Alzheimer's and not ignore it.
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit karenmartel.com to explore our comprehensive programs:
Bioidentical Hormone Replacement Therapy
Individualized Weight Loss Programs
Peptide Therapy for weight loss
Your host: Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert
How to Beat Carb Addiction and Become Carb Sober with Dr. Lisa Wiedeman
Saturday, September 28, 2024 • Duration 01:30:18
Dr. Lisa Wiedeman is an optometric physician with over 33 years in practice. She practices root cause healing. So many ocular diseases & disorders present themselves after long-term eating of processed foods. She herself suffered from sugar/carb/processed food addiction and researched and came to eating a carnivore diet in 2009, over 15 years ago. She now dedicates most of her time providing one on one coaching, hosting coaching groups, Carnivore Beach Retreats and educating viewers on her YouTube channels.
Alongside Dr. Wiedeman in this episode, we discuss the many health benefits she has experienced from her diet, including improved eye health and overall well-being. We challenge societal norms around diet and alcohol consumption, offering practical strategies to resist peer pressure and prioritize long-term health. Additionally, we discuss the psychological dimensions of food addiction, the importance of natural light, and the power of community support in maintaining a healthy lifestyle.
In this episode:
How processed foods contribute to various health issues, including eye diseases.
Why the carnivore diet is particularly beneficial for those with sugar and carb addictions.
How Dr. Wiedeman's personal battle with food addiction led her to a meat-centric lifestyle.
How societal pressures glamorize unhealthy habits like drinking, especially among women.
Why making empowered health choices can help resist peer pressure and improve well-being.
How food addiction intersects with other addictions and impacts psychological health.
How natural light and sun exposure are essential for maintaining eye health.
Why traditional wisdom on sunscreen usage may need re-evaluation.
How community support plays a vital role in maintaining a healthy lifestyle.
Why short-term commitments like 30-day challenges can help in testing new health habits.
How the carnivore diet can lead to unexpected improvements in conditions like depression and anxiety.
Why women may approach the carnivore diet differently than men and face unique challenges.
How Dr. Wiedeman uses her platform to educate and coach others on the benefits of a carnivore lifestyle.
Gut Health, Hormones, and Mental Wellness Uncovered with Tina Anderson
Tuesday, September 24, 2024 • Duration 01:03:40
Today we're talking all about the link between gut health and mental wellness for women navigating midlife challenges like perimenopause and menopause. I'm joined by Tina Anderson, CEO and co-founder of Just Thrive. Tina shares her journey from a high-stress career to discovering the profound impact of the gut microbiome on her own hormonal balance and mental state. We discuss innovative spore-based probiotics that survive the gastric environment and significantly alter gut flora, offering promising benefits for conditions such as stress, anxiety, autoimmune diseases, and chronic inflammation. We also give advice on diet, lifestyle changes, and the potential of probiotics to revolutionize mental wellness and hormone balance.
In this episode:
Why hormonal changes during midlife disrupt the gut microbiome and impact mental state.
An introduction to innovative probiotics and prebiotics designed to support gut health.
The science behind Bacillus spores and their ability to survive the harsh gastric environment.
How spore-based probiotics can significantly alter gut flora for better health.
Why a healthy microbiome effectively manages autoimmune diseases and mental health issues.
The relationship between gut health and brain function, including neurotransmitter production and inflammation.
Details on a study from the University of North Texas revealing leaky gut prevalence in healthy individuals.
How spore-based probiotics can help tackle health challenges like asthma, allergies, and chronic diseases.
Differences between spore-based probiotics and traditional probiotics in surviving the gastric system.
How the role of gut health in processing hormones impacts mental health.
Just Thrive's flagship product with Bacillus strains aiding gut health and mental wellness.
Bifidobacterium longum 1714's role in reducing stress perception and balancing cortisol levels.
How to improve gut health, reduce reliance on SSRIs, and manage stress.
What connection exists between prebiotics, probiotics, and overall wellness.
Testimonials highlighting the transformative effects of gut health on energy levels.
Thyropause: The Silent Thyroid Crisis in midlife Women!
Saturday, September 21, 2024 • Duration 01:09:03
Let's get into the intricate relationship between thyroid health and menopause, which I refer to as thyropause. In this episode, I'm explaining how the significant drop in estrogen and progesterone can mimic and exacerbate thyroid issues. We'll explore the common symptoms that overlap between hypothyroidism and menopause, such as fatigue, weight gain, and hair thinning, and emphasize the importance of comprehensive hormone and thyroid testing. We also discuss the profound impact of stress on gut and thyroid health, looking at groundbreaking insights from a 2015 meta-analysis. We'll examine the complexities of subclinical hypothyroidism, personalized hormone optimization strategies, and how to support thyroid health during midlife transitions.
In this episode:
How the thyroid gland is affected during perimenopause and post-menopause.
Symptoms like fatigue, weight gain, dry skin, and hair thinning overlapping with thyroid issues.
Why monitoring thyroid levels alongside other hormones is crucial for midlife women.
How chronic stress and elevated cortisol levels disrupt gut health and thyroid function.
Why the gut microbiome is essential for thyroid hormone conversion.
How subclinical hypothyroidism can be influenced by genetics, heavy metals, and stress.
How hormone replacement therapy can impact thyroid function.
Why estrogen and progesterone levels should be balanced to support thyroid health.
How stress-induced leaky gut contributes to diseases like diabetes, heart disease, and autoimmune conditions.
Testosterone therapy and how it can reduce thyroid autoimmunity antibodies.
How personalized hormone optimization strategies can support thyroid health.
Why comprehensive lab testing is essential for accurate diagnosis and treatment.
How hormone replacement therapy can both help and hinder thyroid function.
Why thyroid issues can be exacerbated by midlife stress and hormonal changes.
How estrogen and progesterone influence thyroid hormone receptor sensitivity.
Quick Hits: How to Heal Your Metabolism with Kate Deering
Tuesday, September 17, 2024 • Duration 23:27
Welcome to Quick Hits: Blasts from The Past. Join Karen as she explores her podcast archives, offering you short, impactful excerpts from standout episodes. In just 15 minutes, you'll experience the essence of past conversations, packed with valuable insights and memorable moments from our guests. If you want to dive deeper, you'll find links to the full episodes in the show notes below. Listen to the full episode: https://karenmartel.com/how-to-heal-your-metabolism-with-kate-deering/
Your metabolism has everything to do with whether or not your body is able to lose weight. Many women do not realize that their metabolism is under functioning. There are many things that can influence ones metabolism including yoyo dieting, chronic low carb diets and fasting, thyroid issues, adrenal dysfunction, infections and so much more. Without a proper functioning metabolism the body will not be able to lose weight and keep it off.
In this interview I talk to metabolism expert Kate Deering. Kate for over 25 years has been involved in the health and fitness industry helping men and women of all ages achieve optimal health and wellness. Kate went from being a health fanatic who worked out for hours a day and constantly restricted her food. She looked great but felt awful and her health only continued to deteriorate. She realized she was doing everything wrong and went on a mission to heal her metabolism and find true health.
For over 25 years Kate Deering has been involved in the health and fitness industry helping men and women of all ages achieve optimal health and wellness. Her expertise is based on certifications as a CHEK Exercise Coach, CHEK Holistic Lifestyle Coach 2, Olympic Lifting Coach, Z-health practitioner and a Certified Nutritional Consultant. Kate is the author of the book, "How to Heal Your Metabolism", which gives a completely different perspective on what is healthy for you and what is not.
In this episode
How Kate went from working out two hours a day and eating a low carb diet to feeling tired, having unexplained weight gain and other hormonal dysfunctions.
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit to explore our comprehensive programs: Your host: Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.
Visit karenmartel.com to explore our comprehensive programs:
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.
Visit karenmartel.com to explore our comprehensive programs:
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.
Visit karenmartel.com to explore our comprehensive programs:
LMNT: Order your LMNT electrolytes today and get a FREE 8 pack of samples! Plus try it risk free, they have a no-questions-asked refund policy – you don't even have to send it back! www.drinklmnt.com/KarenMartel
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.
Visit karenmartel.com to explore our comprehensive programs:
For a limited time, you can save 20% off a 90 day bottle of Just Thrive probiotic at https://justthrivehealth.com/discount/Hormone with coupon code: HORMONE
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.
Visit karenmartel.com to explore our comprehensive programs:
Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.
Visit karenmartel.com to explore our comprehensive programs:
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