Stroke Alert – Details, episodes & analysis

On Episode 58 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the November 2025 issue of Stroke: "Fingolimod as a Potential Cerebroprotectant Results From the Stroke Preclinical Assessment Network" and "Apixaban and Recurrent Stroke Risk With Left Ventricular Dysfunction: A Secondary Analysis of the ARCADIA Trial." She also interviews Drs. Aaron Rodriguez-Calienes and Santiago Ortega-Gutierrez about their article "Endovascular Thrombectomy Versus Best Medical Therapy for Large Vessel Occlusion Stroke Beyond 24 Hours: A Systematic Review and Meta-Analysis."

For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251114.13070

On Episode 57 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the October 2025 issue of Stroke: "Oxygen Extraction Fraction on Baseline MRI Predicts Infarction Growth in Successfully Reperfused Patients" and "Tadalafil Treatment in Patients With Cerebral Small Vessel Disease: The ETLAS-2 Randomized Clinical Trial." She also interviews Dr. Thomas Meinel on the article "Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use."

For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251008.578434

On Episode 48 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the January 2025 issue of Stroke: "Hypoglycemic Events May Trigger Acute Ischemic Stroke Within 30 Days in Those With Diabetes: A Case-Crossover Study" and "Efficacy and Safety of a Dedicated Device for Cerebral Venous Thrombectomy: A Pilot Randomized Clinical Trial." She also interviews Drs. Johanna Ospel and Umberto Pensato about their article "Cerebral Infarct Growth: Pathophysiology, Pragmatic Assessment, and Clinical Implications."

For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250113.68216

On Episode 47 of the Stroke Alert Podcast, host Dr. Negar Asdaghi is joined by Dr. Ashutosh Jadhav, Professor of Neurology and Neurosurgery at the Barrow Neurological Institute, for the 2024 Ralph Sacco Review of Top Cerebrovascular Research. In honor of the late Dr. Ralph L. Sacco, former Editor-in-Chief of Stroke, who died in January 2023, Drs. Asdaghi and Jadhav review some of the top cerebrovascular science published in any journal or presented at any scientific forum throughout the past year.

For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20241213.415139

On Episode 46 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the November 2024 issue of Stroke: "Cerebrovascular Events in Patients Undergoing Transcatheter Aortic Valve Replacement: A Review" and "Oxygen Extraction Fraction Mapping on Admission Magnetic Resonance Imaging May Predict Recovery of Hyperacute Ischemic Brain Lesions After Successful Thrombectomy: A Retrospective Observational Study." She also interviews Drs. Mitch Wilson and Vasileios-Arsenios Lioutas about their article "Association of Anticoagulant Use With Hemorrhage Location and Etiology in Incident Spontaneous Intracerebral Hemorrhage."

For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20241112.907388

On Episode 45 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the October 2024 issue of Stroke: "Cigarette Smoking and Observed Growth of Unruptured Intracranial Aneurysms: A Systematic Literature Review and Meta-Analysis" and "Clinical and Prognostic Characteristics of Acute BAD–Related Stroke: A Multicenter MRI–Based Prospective Study." She also interviews Dr. Vignan Yogendrakumar about his article "Emerging Adjuvant Thrombolytic Therapies for Acute Ischemic Stroke Reperfusion."

For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20241007.116951

On Episode 44 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the September 2024 issue of Stroke: "Stroke Risk After Emergency Department Treat-and-Release Visit for a Fall" and "Higher Risk of Mental Illness in Patients with Diagnosed and Untreated, Unruptured Intracranial Aneurysm: Findings from a Nationwide Cohort Study."  She also interviews Dr. Yutong Chen and Professor Hugh Markus about the article "Improved Dementia Prediction in Cerebral Small Vessel Disease Using Deep Learning–Derived Diffusion Scalar Maps From T1," published in Stroke.

For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240913.368707

On Episode 43 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the August 2024 issue of Stroke: "Diagnostic Accuracy of Posterior/Anterior Periventricular WMH Ratio to Differentiate CAA From Hypertensive Arteriopathy" and "Statin Overuse in Cerebral Ischemia Without Indications: Systematic Review and Annual US Burden of Adverse Events." She also interviews Dr. Gang Li about the article "Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke," published in The New England Journal of Medicine.

For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240726.908961

On Episode 42 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the July 2024 issue of Stroke: "Dual Antiplatelet Therapy After Embolic Stroke of Undetermined Source: A Subgroup Analysis of the CHANCE-2 Trial" and "Risk of Stroke in Women Using Levonorgestrel-Releasing Intrauterine Device for Contraception." She also interviews Dr. Manabu Inoue about his article "Expanding the Treatable Imaging Profile in Patients With Large Ischemic Stroke: Subanalysis From a Randomized Clinical Trial."

On Episode 41 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the June 2024 issue of Stroke: "Global, Regional, and National Burdens of Stroke in Children and Adolescents From 1990 to 2019: A Population-Based Study" and "Head Injury and Risk of Incident Ischemic Stroke in Community-Dwelling Adults." She also interviews Dr. Raul Nogueira about his article "Endovascular Versus Medical Management in Distal Medium Vessel Occlusion Stroke: The DUSK Study" and highlights some of the science presented at the recent European Stroke Organisation Conference.