More of us are turning to products containing mushroom extracts, with the medicinal fungi market now worth billions of pounds. Promises of benefits to mental and physical health have seen its popularity spill over from wellness influencers to the shelves of Marks & Spencer – but is there any scientific evidence behind these claims? Ian Sample chats to Madeleine Finlay about the appeal of mushroom drinks and supplements, and hears from the mycologist Prof Nik Money on what we really know about how fungi can affect our minds and bodies. Help support our independent journalism at theguardian.com/sciencepod

The chancellor, Rachel Reeves, has promised £14bn of investment to build the Sizewell C nuclear power plant, kicking off what the energy secretary, Ed Miliband, says will be a ‘golden age for clean energy abundance’. But for critics, the technology’s high costs and lengthy construction times have always eclipsed the benefits of abundant low-carbon electricity. Ian Sample is joined by the Guardian energy correspondent Jillian Ambrose to find out why the UK government is backing nuclear and whether it will help Britain hit its target of net zero by 2050. Help support our independent journalism at theguardian.com/sciencepod

Doctors in the US have become the first to treat a baby with a customised gene-editing therapy after diagnosing the child with a severe genetic disorder that kills about half of those affected in early infancy. Ian Sample explains to Madeleine Finlay how this new therapy works and how it paves the way for even more complex gene editing techniques. David Liu, a professor at the Broad Institute of MIT and Harvard and the inventor of these therapies, also describes the barriers that could prevent them reaching patients, and how he thinks they can be overcome. Help support our independent journalism at theguardian.com/sciencepod

Artificial intelligence companies have lofty ambitions for what the technology could achieve, from curing diseases to eliminating poverty. But the energy required to power these innovations is threatening critical environmental targets. Madeleine Finlay hears from the Guardian’s energy correspondent, Jillian Ambrose, and UK technology editor, Alex Hern, to find out how big AI’s energy problem is, and whether it can be solved before it is too late. Help support our independent journalism at theguardian.com/sciencepod

Same-sex sexual behaviours have been reported in a wide variety of species, and a new study suggests that, although animal scientists widely observe it, they seldom publish about same-sex sexual behaviour in primates and other mammals. To find out why and to hear about some of the examples of sexual diversity from the animal kingdom, Ian Sample hears from Josh Davis, a science writer at the Natural History Museum in London and author of the book A Little Gay Natural History. Help support our independent journalism at theguardian.com/sciencepod

You might have noticed that everyone has recently become a bit obsessed with blood sugar, or glucose. Wellness firms such as ZOE here in the UK – as well as Nutrisense, Levels and Signos – claim to offer insights into how our bodies process food based on monitoring our blood glucose, among other things. But many researchers have begun to question the science behind this. To find out what we know about blood glucose levels and our health, and whether the science is nailed down on personalised nutrition, Ian Sample hears from philosopher Julian Baggini, academic dietician Dr Nicola Guess of Oxford University and ZOE’s chief scientist, and associate professor at Kings College London, Dr Sarah Berry. Help support our independent journalism at theguardian.com/sciencepod

Recent research has suggested a global reproductive crisis could be in the offing, with researchers in Israel saying average sperm counts may have more than halved in the past 40 years. But a study published last month appears to call this narrative into question. Ian Sample is joined by the Guardian’s science correspondent Nicola Davis to unpick why these studies have come to different conclusions – and what could be causing the crisis, if declines are as dramatic as they appear. Help support our independent journalism at theguardian.com/sciencepod

As she steps down as the Green party’s first, and so far only, MP, Caroline Lucas tells Madeleine Finlay what it’s been like as the sole Green voice in parliament for the past 14 years, her hopes for her party in Thursday’s UK general election, and what she plans to do in her life beyond politics. Help support our independent journalism at theguardian.com/sciencepod

Psychologists usually expect ambivalence to be a driver of political apathy. But a new study appears to show a link between ambivalence in our views and the likelihood that we’ll support extremist actions. Madeleine Finlay speaks to the study’s co-author Richard Petty, professor of psychology at Ohio State University, to find out what pushes people to take extreme actions, how politics could be driving this behaviour and how it could be combated. Help support our independent journalism at theguardian.com/sciencepod

Anyone who has had a urinary tract infection knows how agonising they can be. Some infections go away on their own, but many need antibiotics. Beneath the surface of this very common infection lie many mysteries, unanswered questions, and unnecessary suffering. And it gets to the heart of the challenge of tackling antimicrobial resistance. Madeleine Finlay speaks to Dr Jennifer Rohn, head of the centre for urological biology at University College London, about what we now understand about how UTIs take hold, and the complexity surrounding their treatment. Help support our independent journalism at theguardian.com/sciencepod

Ian Sample and science correspondent Hannah Devlin discuss some of the science stories that have made headlines this week, from a glimpse of a black hole awakening, to a new blood test that can detect Parkinson’s seven years before symptoms appear, and a study exploring how some people manage to avoid Covid infection. Help support our independent journalism at theguardian.com/sciencepod

Last week more than 400 scientists signed an open letter to political parties urging ambitious action on the environment to prevent making Britain and the world ‘more dangerous and insecure’. Now that the main parties’ manifestos have all been released, Ian Sample is joined by the global environment editor, Jon Watts, and the biodiversity reporter, Phoebe Weston, to find out what the manifestos have to say about nature and climate, and whether anyone is promising the level of action scientists are asking for. Help support our independent journalism at theguardian.com/sciencepod

Here in the UK talking about the weather is already a national pastime, but this month the water-cooler weather chat has ramped up a notch as rain, grey skies and biting temperatures have put summer firmly on hold. Ian Sample talks to Matt Patterson, a postdoctoral research scientist in the Department of Meteorology at the University of Reading, to find out what’s causing the chilly weather, whether it’s really as unusual as it seems, and whether any sun is on the horizon for the UK. Help support our independent journalism at theguardian.com/sciencepod

In March 2021, the Toronto-based reporter Leyland Cecco heard about a memo sent by New Brunswick health officials that warned about a possible unknown neurological syndrome thought to be affecting about 40 people. Since then the story has taken many twists and turns, most recently with a peer-reviewed study that concludes there is no mystery illness after all. Cecco tells Madeleine Finlay about the devastating symptoms that patients experienced, and why the research is unlikely to resolve the conflict over what has been causing them. Help support our independent journalism at theguardian.com/sciencepod

Ian Sample hears from Linda Geddes about her recent trip to the Netherlands to try cultivated meat sausages, courtesy of the company Meatable. Advocates say that cultivated meat could be the future of sustainable and ethical meat production. Linda explains how they’re made, how their carbon footprint compares with traditional meat and most importantly … what they taste like!. Help support our independent journalism at theguardian.com/sciencepod

A court in the Philippines has banned the commercial growth of golden rice, a genetically modified rice which was created to help tackle vitamin A deficiency in developing countries. It’s just the latest twist in a long and controversial journey for this rice. Ian Sample hears from the Observer science and environment editor, Robin McKie, and from Glenn Stone, a research professor of environmental science at Sweet Briar College in Virginia who is also an anthropologist who has studied golden rice, about why it has taken so long for this potentially life-saving technology to reach the fields, if it is the silver bullet so many had hoped for, and whether this ban is really the end of the story. Help support our independent journalism at theguardian.com/sciencepod

For a long time, western science and Indigenous knowledge have been seen as distinct ways of learning about the world. But as we plunge the planet deeper into environmental crises, it is becoming clear that it is time to pay attention to both. Bridging that gap has been the driving force behind the career of the botanist and author of Braiding Sweetgrass, Robin Wall Kimmerer. She tells Madeleine Finlay what we can learn from the most ancient plants on Earth, why we need to cultivate gratitude for the natural world and what western science can learn from Indigenous knowledge. Help support our independent journalism at theguardian.com/sciencepod

It’s been a busy week in the world of artificial intelligence. OpenAI found itself in hot water with Scarlett Johansson after launching its new chatbot, Sky, drawing comparisons to the Hollywood star’s character in the sci-fi film Her. In South Korea, the second global AI summit took place, and a report from the Alan Turing Institute explored how AI could influence elections. The Guardian’s UK technology editor, Alex Hern, tells Madeleine Finlay about what’s been happening. Help support our independent journalism at theguardian.com/sciencepod

Concrete is strong and durable – which is why it’s the basis for so much of our infrastructure. It’s also terrible for the planet, due to one key ingredient: cement, which is responsible for almost 90% of concrete emissions. Researchers have now found a way to recover old cement while also reducing the environmental impact of recycling steel. Madeleine Finlay speaks to Julian Allwood, professor of engineering and the environment at the University Of Cambridge, to find out how the process works, and what it could mean for the emissions generated by the construction industry. Help support our independent journalism at theguardian.com/sciencepod

On Tuesday a British man died and several others were injured when their plane encountered severe turbulence between London and Singapore. And it looks like this kind of turbulence is something we’ll have to get used to. Last year a study found severe clear-air turbulence had increased by 55% between 1979 and 2020. Ian Sample speaks to Guy Gratton, associate professor of aviation and the environment at Cranfield University, to find out why this is happening, and whether there’s anything we can do to reverse the trend.. Help support our independent journalism at theguardian.com/sciencepod

Right now, across much of the midwestern and eastern US, trillions of cicadas are crawling out from the soil. And this year is extra special, because two broods are erupting from the ground at once. The first brood hasn’t been seen for 13 years, the other for 17 years and the last time they emerged together Thomas Jefferson was president. Ian Sample speaks to entomologist Dr Gene Kritsky to find out what’s going on, why periodical cicadas emerge in cycles of prime numbers and how they keep time underground. Help support our independent journalism at theguardian.com/sciencepod

Last week the founder of the dating app Bumble forecasted a near future dating landscape where AI ‘dating concierges’ filter out prospective partners for us. But does AI, or even science, really understand what makes two people compatible? Madeleine Finlay speaks to Amie Gordon, assistant professor of psychology at the University of Michigan, to find out what we know about why two people go the distance, and why she and her colleague associate professor of sociology Elizabeth Bruch, are designing their own dating app to learn more.. Help support our independent journalism at theguardian.com/sciencepod

As AI systems have grown in sophistication, so has their capacity for deception, according to a new analysis from researchers at Massachusetts Institute of Technology (MIT). Dr Peter Park, an AI existential safety researcher at MIT and author of the research, tells Ian Sample about the different examples of deception he uncovered, and why they will be so difficult to tackle as long as AI remains a black box. Help support our independent journalism at theguardian.com/sciencepod

Sales of cottage cheese are booming thanks to a boost from protein-hungry social media influencers. But do we really need all this extra protein? Madeleine Finlay speaks to Joanne Slavin, a professor of food science and nutrition at the University of Minnesota, to find out what exactly protein is doing in our bodies, and what happens to it when we consume it in excess. Help support our independent journalism at theguardian.com/sciencepod

Geoengineering, the controversial set of techniques that aim to deliberately alter the Earth’s climate system, may be inching a step closer to reality with the announcement that UK scientists will be conducting real-world experiments in the coming years. To understand what’s happening, Ian Sample is joined by the Guardian environment editor Damian Carrington. Damian explains what the experiments will entail and why scientists are so divided on whether pursuing this research is a good idea. Help support our independent journalism at theguardian.com/sciencepod

A study has found that more than two dozen US coastal cities are sinking by more than 2mm a year. It’s a similar picture across the world. Nearly half of China’s major cities, as well as places such as Tehran and Jakarta, are facing similar problems. These issues are compounded by sea level rises caused by global heating. Madeleine Finlay speaks to Prof Manoochehr Shirzaei of Virginia Tech University and Prof Robert Nicholls of the University of East Anglia to find out what’s making our cities sink and whether anything can be done to rescue them from the sea. Help support our independent journalism at theguardian.com/sciencepod

Glioblastomas are an extremely aggressive type of brain tumour, which is why the news this week of a vaccine that has shown promise in fighting them is so exciting. And this comes right off the back of the announcement of another trial of the world’s first personalised mRNA vaccine for melanoma, a kind of skin cancer. Ian Sample talks to Prof Alan Melcher of the Institute of Cancer Research about how these vaccines work and whether they could one day be used to target cancer before it is even detectable on scans. Help support our independent journalism at theguardian.com/sciencepod

Guardian Seascapes reporter Karen McVeigh tells Madeleine Finlay about a recent trip to the Galápagos Islands, where mounds of plastic waste are washing up and causing problems for endemic species. Tackling this kind of waste and the overproduction of plastic were the topics on the table in Ottawa this week, as countries met to negotiate a global plastics treaty. But is progress too slow to address this pervasive problem?. Help support our independent journalism at theguardian.com/sciencepod

As bird flu is confirmed in 33 cattle herds across eight US states, Ian Sample talks to virologist Dr Ed Hutchinson of Glasgow University about why this development has taken scientists by surprise, and how prepared we are for the possibility it might start spreading among humans. Help support our independent journalism at theguardian.com/sciencepod

Labradors are known for being greedy dogs, and now scientists have come up with a theory about the genetic factors that might be behind their behaviour. Science correspondent and flat-coated retriever owner Nicola Davis visits Cambridge University to meet Dr Eleanor Raffan and Prof Giles Yeo to find out how understanding this pathway could help us treat the obesity crisis in humans. Help support our independent journalism at theguardian.com/sciencepod

Billed as a rival to the Olympic Games, the Enhanced Games, set to take place in 2025, is a sporting event with a difference; athletes will be allowed to dope. Ian Sample talks to chief sports writer Barney Ronay about where the idea came from and how it’s being sold as an anti-establishment underdog, and to Dr Peter Angell about what these usually banned substances are, and what they could do to athletes’ bodies. Help support our independent journalism at theguardian.com/sciencepod

What can sound tell us about nature loss? Guardian biodiversity reporter Phoebe Weston tells Madeleine Finlay about her visit to Monks Wood in Cambridgeshire, where ecologist Richard Broughton has witnessed the decline of the marsh tit population over 22 years, and has heard the impact on the wood’s soundscape. As species lose their habitats across the world, pioneering soundscape ecologist Bernie Krause has argued that if we listen closely, nature can tell us everything we need to know about our impact on the planet. Help support our independent journalism at theguardian.com/sciencepod

This week, in a landmark case, the European court of human rights ruled that Switzerland’s weak climate policy had violated the rights of a group of older Swiss women to family life. Ian Sample talks to Europe environment correspondent Ajit Niranjan about why the women brought the case and what the ruling could mean for future climate policy.. Help support our independent journalism at theguardian.com/sciencepod

The Nobel prize-winning British physicist Peter Higgs has died aged 94. The confirmation in 2012 of the existence of the Higgs boson particle, five decades after Higgs had first theorised its existence, paved the way for his 2013 Nobel win. Nicknamed ‘the god particle’, the Higgs boson was part of an attempt to explain why the building blocks of the universe have mass. Ian Sample and Madeleine Finlay look back on the life and legacy of a giant of science. Help support our independent journalism at theguardian.com/sciencepod

For most people seeing a total solar eclipse is a once in a lifetime experience. But for scientists it can be a fleeting chance to understand something deeper about their field of research. Madeleine Finlay meets solar scientist prof Huw Morgan, of Aberystwyth University, and Adam Hartstone-Rose, professor of biological sciences at NC State University, to find out what they hoped to learn from 8 April’s four minutes of darkness.. Help support our independent journalism at theguardian.com/sciencepod

For a long time the appendix was considered disposable. After all, millions of people have theirs removed each year and go on to live healthy lives. But as Heather F Smith, a professor of anatomy at Midwestern University tells Ian Sample, researchers are increasingly understanding what this small worm-shaped organ may be bringing to the table in terms of our health. Smith explains how the appendix is linked to both our immune system development and gut health, and why she thinks an increasing interest in the microbiome may bring it to greater prominence. Help support our independent journalism at theguardian.com/sciencepod

Psychologist Chris French has spent decades studying paranormal claims and mysterious experiences, from seemingly-impossible coincidences to paintings that purportedly predict the future. Ian Sample sits down with French to explore why so many of us end up believing in, what he terms, ‘weird shit’, and what we can learn from understanding why we’re drawn to mysterious and mystic phenomena. Help support our independent journalism at theguardian.com/sciencepod

Being more flexible than the average person can have its advantages, from being great at games such as Limbo to feeling smug in yoga class. But researchers are coming to understand that being hypermobile can also be linked to pain in later life, anxiety, and even long Covid. Madeleine Finlay hears from the science correspondent Linda Geddes about her experience of hypermobility, and finds out what might be behind its link to mental and physical health. Help support our independent journalism at theguardian.com/sciencepod

On 28 March it’s the 60th anniversary of the discovery of Epstein-Barr virus, the most common viral infection in humans. The virus was first discovered in association with a rare type of cancer located in Africa, but is now understood to be implicated in 1% of cancers, as well as the autoimmune disease multiple sclerosis, among others. Ian Sample meets Lawrence Young, professor of molecular oncology at Warwick Medical School, to hear the story of this virus, and how understanding it might help us prevent and treat cancer and other illnesses.. Help support our independent journalism at theguardian.com/sciencepod

The sun is currently ramping up to hit the peak of its 11-year activity cycle. In the past few days, powerful solar eruptions have sent a stream of particles towards Earth which are set to produce spectacular auroras in both hemispheres. But these kinds of geomagnetic storms can also have less appealing consequences. Madeleine Finlay speaks to Dr Lisa Upton, a solar scientist at the Southwest Research Institute, about how the mysterious inner workings of the sun create space weather, how solar events can significantly disrupt Earth’s infrastructure, and whether we are prepared for the worst-case scenario. Help support our independent journalism at theguardian.com/sciencepod

In late 2016, US officials in Cuba’s capital began experiencing a mysterious and often debilitating set of symptoms that came to be known as Havana syndrome. As two new studies into the condition are published, Ian Sample speaks to the Guardian’s world affairs editor, Julian Borger, who has been following the story, and to the consultant neurologist Prof Jon Stone, about what could be behind the condition. Help support our independent journalism at theguardian.com/sciencepod

A growing movement of ecologists, lawyers and artists is arguing that nature should have legal rights. By recognising the rights of ecosystems and other species, advocates hope that they can gain better protection. Madeleine Finlay speaks to the Guardian’s global environment editor, Jonathan Watts, about where this movement has come from and why the UK government has dismissed the concept, and hears from Cesar Rodriguez-Garavito of NYU School of Law about how he is finding creative ways to give rights to nature. Help support our independent journalism at theguardian.com/sciencepod

Ian Sample and science correspondent Hannah Devlin discuss some of the science stories that have made headlines this week, from a new theory challenging the existence of dark matter to an alarming study about the possible impact of microplastics on our health and a glimpse of a ‘waterworld with a boiling ocean’ deep in space. Help support our independent journalism at theguardian.com/sciencepod

For some people, going bald or experiencing thinning hair can have a significant impact on mental wellbeing and self confidence. Madeleine Finlay speaks to Rudi Zygadlo about how it affected him and what he eventually did about it, and to consultant dermatologist and hair specialist Dr Sharon Wong about what exactly is going on when our hair thins, which treatments are available to help, and what we can expect from new technologies in the pipeline. Help support our independent journalism at theguardian.com/sciencepod

Ian Sample speaks to the Guardian’s health editor, Andrew Gregory, about the worrying global rise in cancers in under-50s, and hears from Yin Cao, an associate professor in surgery and medicine at Washington University in St Louis, who is part of a team conducting a huge study into why young people are developing bowel cancer at record rates. Help support our independent journalism at theguardian.com/sciencepod

We all know the cliches about older siblings being responsible, younger ones being creative, and middle children being peacemakers. But is there any evidence our position in the family has an impact on our personality? Madeleine Finlay meets Dr Julia Rohrer, a personality psychologist at the University of Leipzig, to unpick the science behind our intuition about birth order. Help support our independent journalism at theguardian.com/sciencepod

Science correspondent Hannah Devlin joins Ian Sample to discuss three intriguing science stories from the week, from a global study that puts the UK third from bottom when it comes to flourishing, to a man who intentionally suffered more than 200 snake bites in the quest to find a universal antivenom and a breakthrough in the quest to understand the contents of the charred Herculaneum scrolls buried when Mount Vesuvius erupted. Help support our independent journalism at theguardian.com/sciencepod

We wanted to bring you this episode from our new series, Black Box. In it, Michael Safi explores seven stories and the thread that ties them together: artificial intelligence. In this prologue, Hannah (not her real name) has met Noah and he has changed her life for the better. So why does she have concerns about him? If you like what you hear, make sure to search and subscribe to Black Box, with new episodes every Monday and Thursday.. Help support our independent journalism at theguardian.com/sciencepod

It’s thought that about 15% of us are affected by tinnitus, and despite its potentially debilitating impact on mental health and quality of life, there isn’t any cure for the condition. Madeleine Finlay speaks to John, who has used CBT techniques to learn to live well with his tinnitus, and Dr Lucy Handscomb, a tinnitus researcher who is involved in trialling a new app that could hold promise for sufferers.. Help support our independent journalism at theguardian.com/sciencepod

Electric cars might seem like a no-brainer on a warming planet, but there are plenty of people who remain sceptical about everything from their battery life to their carbon impact and the environmental and human rights costs of their parts. Madeleine Finlay consults Auke Hoekstra, known as the internet’s ‘EV debunker in chief’, to unpick the myths, realities and grey areas surrounding electric cars. Help support our independent journalism at theguardian.com/sciencepod