Real Science Exchange-Dairy – Details, episodes & analysis

Dr. Overton presented on this topic in a Real Science Lecture series webinar on July 10, 2024. You can find it at www.balchem.com/realscience. This episode takes a deeper dive into the conversation.

Dr. Overton begins by reminding listeners of the vast number of changes occurring in the fresh cow during the first two to three weeks after calving. Body fat and protein mobilization, some systemic inflammation, the potential for elevated NEFAs and ketones, and calcium dynamics all play a role in how the fresh cow starts her lactation period. (7:31)

When consulting with clients, Dr. Faldet uses research to guide his decisions. He likes to implement a 14-day pen for fresh cows, ranging from 10-17 days. He evaluates things like stocking rates, lockup times, and cow comfort, along with fine-tuning a diet for each individual farm setting. (9:14)

The panel discusses the importance of increasing effective fiber along with starch in fresh cow diets. Without adequate effective fiber in the diet, the risk of acidosis increases, resulting in cows going off feed. There is no silver bullet; each farm’s fresh cow diet is going to be different due to different forage bases and timing in the fresh cow group. (13:02)

Both Dr. Faldet and Dr. Overton stressed the diet is only one component of a successful fresh cow program. Other critical pieces include stocking rate, availability of feed, water quantity and quality, and cow comfort. Dr. Faldet suggests that if you do all these non-diet factors right, you could probably maneuver closeup and fresh pens a little differently and make the diet work with the ingredients you have. Dr. Overton’s group is conducting survey work evaluating the variability in particle size in closeup diets. A pilot study showed that as particle size variability increased, so did fresh cow health issues and poor postpartum metabolic status. (19:10)

Protein requirements of the fresh cow were another topic of Dr. Overton’s webinar. He described a recent experiment evaluating standard and high metabolizable protein concentrations in the diet for closeup and fresh cows. The postpartum MP gave a big milk response, around 15-16 pounds per day for the first 21 days after calving, with a carryover effect of 11-12 pounds of milk for the next 20 days after all cows went back on the same diet. It’s important to note that lysine and methionine were fixed regardless of treatment, so it seems that other amino acids are probably involved in the mechanism of action. (23:06)

Dr. Overton described an experiment designed to evaluate starch and fiber in fresh cow diets where higher fiber digestibility and increased corn in silage resulted in less fiber and more starch than anticipated in the diet. Fresh cows were a bit of a trainwreck, but the problem was resolved once another couple of pounds of straw were added to the diet. On the other hand, you can go too far with increased fiber in fresh cow diets, which results in ketosis, lower intakes, and less milk production. (35:19)

The panel then discusses far-off programs, fat supplementation in fresh cow diets, and vitamin and mineral concentrations for fresh cows. (42:37)

In summary, each panelist shares their takeaways. Dr. Elliott reminds listeners that we should think about starch, fat, fiber, and protein together and how they influence each other rather than considering them individually. Dr. Faldet’s take-home message is to know what your targets and bookends are and really hone in and implement your fresh cow diets accordingly. Dr. Overton suggests that the industry will shift to evaluating fresh cow diets as their own thing rather than trying to tweak a few things from your high cow diet. Implementing fresh cow diets consistently and well is going to be important. (53:30)

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Dr. Callaway presented on this topic in a Real Science Lecture series webinar on June 4, 2024. You can find it at www.balchem.com/realscience. The following podcast takes a deeper dive into the conversation.

For years, probiotics were known as direct-fed microbials (DFMs) in livestock and probiotics in humans. Terminology has been updated to reflect different modes of action and composition. (9:07)

A probiotic is defined as a living microorganism that will be beneficial to the health and/or performance of the host. Prebiotics are fermentable substrates that the host can’t use, but the microbes can. Dr. Steele agrees that terminology and definitions keep evolving; he uses “microbial-based solutions” rather than DFM. He believes that the ever-evolving terminology and definitions have led to some of the skepticism about these products in the industry. He recommends to farmers and nutritionists that a product should have a bare minimum of three publications in high-quality peer-reviewed journals showing efficacy before using them on-farm. (10:13)

Every farm is going to have a different set of challenges and goals that will play a role in determining the right choice of microbial-based solution. Weather and climate, water quality, pathogen challenges, ration grind size, and ration ingredients will all factor into the decision. (17:39)

Both guests agree that we don't know enough about the microbiome in cattle to define what a good versus a bad microbiome looks like. Dr. Steele suggests the next steps in research should look more deeply at the host’s physiological mechanisms in how they’re responding to a probiotic to truly understand when it’s going to work and when it’s not. (21:19)

Dr. Ordway asks how much microbial products could improve the absorption of nutrients. Dr. Steele responds that much of the research so far has focused on digestion and absorption has not been studied much. Some studies in calves fed microbials have shown changes in gut structure and the development of villi, and even papillae in the rumen. That gives us some high-level information about absorption, but we are not close to understanding the nitty gritty of the microbial mechanisms at play in absorption. Dr. Callaway adds that hindgut absorption in ruminants is more important than we have previously thought. Dr. Steele suggests the small and large intestines are equally as important as the forestomach, but they are not as well understood as they’re harder to study in ruminants. The conversation goes on to discuss possible modes of action behind increased liver abscesses observed in beef on dairy operations. (30:12)

Both guests share their thoughts regarding working together across disciplines, especially agronomy researchers since the feed base has such an impact on-farm. They discuss soil microbes, forge inoculants, and silage microbes. (43:23)

Dr. Ordway’s take-home message for nutritionists is to not forget to have conversations with your partners - the producer, the end user, the veterinarian, the crop team and the management team on the farm. Coordinated biology is not just within the animal, it’s all the factors coming into play that have been discussed in this episode. (58:32)

Dr. Steele reiterates his earlier advice to only use microbial-based solutions that have a bare minimum of three publications showing efficacy in a high-ranking journal. He also recommends you choose your metric of measurement properly. Focusing on cattle that are experiencing some stress or metabolic or infectious issues may allow you to truly evaluate the return on investment. There are great microbial solutions out there but you need to use a proven solution from a company that’s research-based. (59:48)

Dr. Callaway echoes Dr. Steele’s recommendation to be slightly cynical about companies that come in to sell you things. Ask how their product works, and ask to see the research. A company that tells you when its product works and when it doesn’t might be more trustworthy than one that says their product always works. Lastly, what does success look like for you as a farmer? Have a measurable, bite-size metric for determining if these products impact your bottom line. (1:01:28)

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This journal club episode comes to you from the 2024 Tri-State Dairy Nutrition Conference. The paper is “Practical Aspects of Reducing Carbon Footprint by Dairy Farms Through Feeding” from the conference proceedings.

In the U.S., livestock competes with oil and gas for the top source of methane emissions. While “carbon-neutral” agriculture may be easy for modelers to show, Dr. Hristov feels this is misleading and probably impossible in practical dairy farming. However, mitigation can be addressed in several directions, and nutrition can have perhaps the largest impact. Management practices, genetic selection, and manure management can be added to achieve large reductions in total methane from an intensive dairy production system. (2:43)

As forage digestibility increases, methane yield and intensity will decrease. A forage with higher digestibility may gain a 10-15% improvement in methane intensity compared to a lower digestible forage. In addition, starch makes less methane than NDF does. Feedlot cattle produce half the methane of a normal dairy cow due to the increased starch in the feedlot diet. We know fats and lipids can decrease methane, but anything higher than 5-6% in the diet will disturb rumen function and lead to poorer performance. Comparing different forages, corn silage produces the least methane, with alfalfa in second place. (6:41)

Feed additives have the potential to deliver compounds for methane mitigation. One of these is 3-nitrooxypropanol (3-NOP), the commercial version of which was developed in Europe. It is approved in Europe and Latin American countries. Australia and New Zealand are also working through the approval process. This compound inhibits the MCR enzyme (methyl coenzyme M reductase) which catalyzes the last step in methanogenesis. Dr. Hristov’s lab has consistently shown a 30% reduction in methane yield when diets containing 3-NOP are fed, with no impact on milk production and a slight increase in milk fat. 3-NOP is quickly metabolized, so it is most useful in a confinement system where it can continuously enter the rumen. The compound is stable in a TMR for up to 24 hours, and the optimum inclusion rate is 60-80 milligrams per kilogram of diet (60-80 ppm). (14:41)

Regarding regulatory approval in the U.S., the FDA has indicated that 3-NOP must be approved as a drug, not as a feed additive. Dr. Hristov has concerns about an adaptation of the cows to the compound. One study in Holland fed 3-NOP for a year, and there was a definite decrease in efficacy over time. Furthermore, efficacy may depend on diet, as 3-NOP is less effective with high NDF diets. It’s unclear if the decrease in efficacy over time is because the microbes break down 3-NOP before it affects methane synthesis or if the microbes shift to a different pathway of methane synthesis. (22:04)

Bromoform, a compound found in red seaweeds, is also a powerful methane mitigator. Dr. Hristov’s lab has observed 60-65% decreases in methane production early in the feeding period, dropping to 20-25% after 200 days. Other issues include the practicality of growing and transporting seaweed, the instability of bromoform, and the fact that bromoform is an ozone-depleting compound and a carcinogen. Seaweed extracts tend to decrease dry matter intake, and thus milk production and milk iodine increase dramatically. (25:54)

In the U.S. dairy system, where manure is usually handled as a liquid, methane emissions from manure and from the cow are equal. Methane digesters and flaring of methane are common mitigation methods. Acidification is another method whereby decreasing pH can decrease methane emissions and ammonia and nitrous oxide losses. Dr. Hristov predicts a lot of additives to decrease methane emissions from manure will eventually be available on the market. (31:16)

3-NOP has little effect on rumen dynamics but may increase butyrate. Dr. Weiss asks if different feed additives have synergistic effects, and Dr. Hristov thinks much more work is needed in this arena. (33:19)

While methane mitigation probably has no silver bullet, many little interventions can add up to a big impact. Looking forward, so many people are working in this area; we will have solutions for methane mitigation. (43:56)

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Guests: 
Dr. Tom Overton, Cornell University
Corwin Holtz, Holtz-Nelson Dairy Consultants

The last 18 months have been challenging for the ag industry, and we've seen a rollercoaster of milk prices throughout the COVID pandemic. As the world begins to normalize, we can now shift our focus to impacting efficiency and profitability across the dairy operation. Tonight, we’re going to get really practical and dig into ways we can improve milk component production. 

Corwin describes that he monitors, on a monthly basis, energy corrected milk, pounds of fat, pounds of protein, ratios relative to dry matter intake, what our energy corrected feed efficiency is. He also looks at our component efficiency, pounds of fat and pounds of protein combined, relative to herd average dry matter intake. 7:22

Dr. Tom Overton discussed how components are heritable. This means some of your herds think about genetics and how they also use those strategies to try to improve, not just milk yield, but also component yields over time. 17:08

There is a concern by many, Corwin Holtz shares, that we're probably not pushing up feed nearly as many times a day as what we should. In his opinion, if we're not close to 12 times a day, we're probably not getting the job done the way we ought to be. 38:26

Dr. Tom Overton discusses that all fractions are going to move up or down together when you talk about milk fat protein or total milk fat percentages. He shares that if we're in a milk fat depression type scenario, they all go down, but the de novos go down proportionally more. It helps us identify where that issue may be, relative to saturated fatty acids. 51:20

From Corwin Holtz’s experience, good fiber digestibility; that's the key to any nutrition program and feeding management. He describes that we deal with a lot of overcrowded barns and that's not going to change. But can we get our feeders and feeding management into a routine that we are not slug feeding? Can any cow at any time that wants to go up and eat has the ability to? I think those are two key things that we continue to press with our clients' day in and day out. 58:06

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Guests: 
Dr. Lance Baumgard, Iowa State University
Dr. Rosemarie Zimbelman, Dairy Nutrition Services
Dr. Bob Collier, University of Idaho

Summer heat is at full strength and that means heat stress for your animals. Tonight, we have brought together a powerhouse roundtable of experts in the field of heat stress management to talk through the physiology and mechanisms for effectively managing the heat.  

Dr. Bob Collier discussed how we have changed our cows in the past 50 years to produce milk production which increases maintenance requirements, making them more sensitive to heat stress and more resistant to cold. 2:50

Dr. Rosemarie Zimbelman discussed some of the advancing technology seen over the past 40 years such as evaporative cooling methods and nutritional strategies improving cattle comfort. 6:10

Dr. Bob Collier discussed the possibility of higher sweat rates in cows but also the negative effect which would be lower milk yields. 16:38

Dr. Rosemarie Zimbelman discussed altering diets in the summer months to reduce heat stress. 20:00

Dr. Lance Baumgard discussed the consequences of heat stress emanating from the gut (leaky gut). This causes an immune response, leading to heat stress and infections like mastitis. 22:06

Dr. Bob Collier discussed the advantage and importance of high-quality water and cost-effective milk production. 31:56

Dr. Lance Baumgard discussed the negative consequences of in utero heat stress and the calf becoming less feed efficient and less productive. 49:52

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Guests:  Dr. Greg Aldrich, K-State University, Dr. Amanda Dainton, K-State University, Dr. Heather Acuff, K-State University, Krystina Lema Almeida, K-State University

In this episode, you’ll feel like we're back on campus because we've gathered together some of the top minds in the Kansas State University pet food program for this week's pubcast. The discussion started at our very first research showcase webinar, which aired on March 16th. We'll feature other university programs going forward. And if you'd like for us to consider showcasing your university program, simply email us anh.marketing@balchem.com. To find a recording of the K-State showcase webinar, go to www.balchem.com/realscience.

Dr. Greg Aldrich discussed some of the successes and careers his students have found in the pet food industry after going through the program at K-State. 

22:15

Dr. Heather Acuff gave advice, to future students, to ask their professors about programs they are interested in joining. Also, nobody needs to tell themselves they are too old to go back to school. 

25:39

Dr. Amanda Dainton discussed the option of internships and immersive experiences for college students. 

26.59

Dr. Heather Acuff discussed probiotics and their possible benefits. As well as integrating vitamins and minerals versus consumers having to worry about doses and mixes for their pets. 
41:27

Krystina Lema Almeida discussed sustainability, product variety and ingredients in the pet food industry. 54:53

Dr. Greg Aldrich discussed how protein will be the biggest challenge for the pet food industry moving forward. With a growing world population, the pet food industry will have to embrace different varieties of protein. 56:21

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Guests:
Dr. Geoff Dahl, University of Florida
Dr. Jimena Laporta, University of Wisconsin-Madison

We are back at the Real Science Exchange and invite you to pull up a chair and join us to discuss the effects of heat stress on late gestation cows. Tonight’s guests, who have worked together on research in this area, Dr. Geoff Dahl with the University of Florida and Dr. Jimena Laporta with the University of Wisconsin-Madison, join Scott Sorrell and Dr. Clay Zimmerman.

Dr. Dahl kicks off the discussion by level setting with the idea that cows have a thermal comfort zone and that it’s not just temperature but also humidity that can stress a cow. 4:44

To get a more accurate stress reading, Dr. Laporta and Dr. Dahl’s research has focused on measuring stress and environmental indicators without getting in contact with the animal. 8:40

Dr. Laporta discusses the stress can continue into future lactation periods of both the dam and the offspring. 16:45

Both researchers highlight their opinion on cow longevity in the herd and how stress can change the length of the cows’ time in the herd. 22:48

While the Florida humidity heightens the stress Dr. Dahl sees in Florida; both researchers highlighted they see seasonal effects on cows everywhere. If lactating cows are under stress for even a week, Dr. Laporta discusses the short-term event will have a long-term impact on the cow. 35:54

Heat stress can also cause acceleration of the maturation process for gestation timing. Dr. Dahl discusses the calf is signaling it is ready to be born based on the increase in the cows’ internal temperature. 45:09

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 Guests: 
Dr. Bill Weiss, The Ohio State University 
Dr. Mat Faulkner, Purina 

Welcome back to the Real Science Exchange. Before we get started tonight, we’d like to share how you can get our t-shirts. There are three steps, either subscribe, follow or like the Real Science Exchange podcast on your favorite podcast platform or on YouTube, take a screenshot and send it to anh.marketing@balchem.com. Include your name, shirt size and mailing address. 

This week, our hosts are joined by Dr. Bill Weiss from The Ohio State University and Dr. Mat Faulkner from Purina. This week’s podcast is a continuation of one of our most highly attended webinars in 2021. If you would like to listen to it, you can find it here: balchemanh.com/realscience. 

Dr. Bill Weiss is from The Ohio State University and has been doing research on minerals since 1978. Dr. Mat Faulkner was a graduate student under Dr. Bill Weiss. He earned his master’s at The Ohio State University and is now a nutritional consultant in Wisconsin for Purina. 

Dr. Bill Weiss discusses the minerals that should not be combined in a diet and that there are many factors that should be taken into account while determining your rations. (00:10:01) 

Both of the guests analyze exactly how much sulfur should be added into your cattle’s diet. (00:17:50) Dr. Bill Weiss reviews the dangers of overfeeding magnesium and copper. (00:34:20) 

Dr. Mat Faulkner discusses the risks of toxicity in zinc and copper and the microbiome effect in the rumen. (00:46:08) 

Both guest speakers analyze factors that may cause oxidative stress. (01:00:33) 

Thank you to our loyal listeners for stopping by once again at the Real Science Exchange to sit with us just for a while. If you like what you heard, please remember to drop us a five-star rating on the way out. 

This podcast is sponsored by Balchem Animal Nutrition and Health.

Guests:
Dr. Tom Jenkins, Clemson University
Dr. Don Palmquist, The Ohio State University
Dr. Kevin Harvatine, Pennsylvania State University

We gather around the Real Science Exchange virtual table for another pubcast with leading researchers to dive into this week’s topic of the history of feeding fat to dairy cattle. Scott Sorrell and Dr. Clay Zimmerman are joined by tonight’s guests who span the history of the topic with Dr. Don Palmquist being one of the founding fathers and Dr. Tom Jenkins also providing much of the depth as we dive in on this topic. Dr. Kevin Harvatine is not new to the Real Science Exchange and we are excited to have him back for this discussion.

Dr. Palmquist and Jenkins discussed the early years of their research finding the right combination, source and ration approach to including fat into dairy cow diets. 9:20

Dr. Jenkins discussed the early failures and how they came to trial making calcium salts and seeing some early success in their research. 19:26

To give perspective on today’s approach, Dr. Harvatine shared he’s seeing a reasonable amount of progress the last couple of years to getting fatty acids rather than extract or crude fat into rations. 29:36

The trio gave their input on the practical limits of fat inclusion. 39:51

With growing herd averages for pounds of milk produced, the experts discussed how to get enough into the diets to meet the growing output. 47:21

Dr. Harvatine discussed his outlook on the future of how fatty acids can modify physiology. 55:48

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Guests: 
Dr. Kevin Harvatine, Pennsylvania State University
Dr. Isaac Salfer, University of Minnesota

We are back at the Real Science Exchange for another pubcast joined by dairy industry professionals. This week our hosts Scott Sorrell and Dr. Clay Zimmerman are joined by Dr. Kevin Harvatine from Penn State University and Dr. Isaac Salfer from the University of Minnesota. The discussion around the table is focused on understanding seasonal and daily rhythms on milk & component yield.

Earlier this year, Dr. Harvatine joined Balchem for the Real Science Lecture Series on the same topic. Click here to check out his lecture: https://tinyurl.com/yfofvkhq

Dr. Salfer has a unique perspective on this topic as he was the PhD student who focused on daily rhythms when he was in school working under Dr. Harvatine. 

For more than 30 years, Dr. Zimmerman has been working in the dairy nutrition industry and he remembers early in his career having discussions with dairies that were curious as to why they were seeing a dip in the milk fat each spring, and that kicked off the discussion around what the research showed with changes in milk fat percentages through the seasons. 10:55

Dr. Salfer discusses that they would like to understand the differences, if any, between the northern and southern hemispheres, but it’s hard to compare apples to apples when many of the southern hemisphere herds are grazing herds. That being said, through his students he has connections to Kenya and they are exploring research there to compare to the U.S. data set. 16:59

Heat stress and seasonal rhythms are often lumped together as factors for changes in milk yield, but Dr. Harvatine explains their research shows it might not be that simple. 24:05

Dr. Harvatine discusses what to consider if a dairy wants to minimize seasonality and maintain a herd at the high point. 37:58

Both of the guests discuss the importance in adjusting rations to maximize input during season shifts. 42:40

If you want one of our new Real Science Exchange t-shirts, make sure to screenshot your rating, review or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address and we’ll get a shirt in the mail to you.

Please subscribe and share with your dairy industry friends to bring more friends to join us around the Real Science Exchange virtual pub table.

This podcast is sponsored by Balchem Animal Nutrition and Health.