Explore every episode of the podcast Real Life Pharmacology - Pharmacology Education for Health Care Professionals
| Title | Pub. Date | Duration | |
|---|---|---|---|
| Gout Pharmacotherapy – Test Prep and Practice Pearls | 05 Nov 2026 | 00:17:52 | |
Gout pharmacotherapy involves more than just treating painful flare-ups. In this episode of Real Life Pharmacology, we review the most commonly used gout medications, including allopurinol, febuxostat, colchicine, probenecid, NSAIDs, and corticosteroids. Learn how these medications work, their indications, important adverse effects, clinically significant drug interactions, and practical prescribing pearls. We also discuss uric acid treatment goals, prevention of recurrent gout attacks, renal dosing considerations, and important medication safety concerns. Whether you are a pharmacist, nurse, physician, or healthcare professional preparing for a board certification exam, this episode will help strengthen your understanding of gout treatment and evidence-based gout pharmacotherapy. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Osteoporosis Medications Part 2 – Test Prep and Practice Pearls | 29 Oct 2026 | 00:16:32 | |
Bisphosphonates are commonly used to treat osteoporosis, but several non-bisphosphonate osteoporosis medications can help reduce fracture risk. Pharmacists should understand the mechanisms, adverse effects, and clinical pearls associated with these alternatives. On this podcast episode, I will cover four of the most commonly used “non-bisphosphonate” osteoporosis medications. Denosumab (Prolia) is a RANKL inhibitor that decreases osteoclast activity and bone resorption. It is administered subcutaneously every six months. Teriparatide (Forteo) and abaloparatide (Tymlos) stimulate bone formation through the parathyroid hormone pathway. These medications may be appropriate for patients at very high fracture risk. Raloxifene (Evista) is a selective estrogen receptor modulator (SERM) that reduces bone resorption. It primarily reduces vertebral fracture risk and may lower the risk of estrogen receptor-positive breast cancer. Important adverse effects include hot flashes and an increased risk of venous thromboembolism. Calcitonin (Miacalcin) inhibits osteoclast-mediated bone resorption. However, its effectiveness for fracture prevention is limited, making it a less-preferred option for long-term osteoporosis treatment. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Osteoporosis Medications – Test Prep and Practice Pearls: Bisphosphonates | 22 Oct 2026 | 00:17:44 | |
Bisphosphonates are commonly used to prevent and treat osteoporosis, making them an important topic for pharmacy, nursing, and medical exams. In this episode of the Real Life Pharmacology Podcast, we review high-yield bisphosphonate facts and practical pearls to help you prepare for exams and improve medication management. Topics covered include:
Whether you are preparing for a pharmacy board exam, studying pharmacology, or reviewing osteoporosis treatment in clinical practice, this episode highlights the key bisphosphonate concepts worth remembering. Listen to the Real Life Pharmacology Podcast for practical medication insights that help connect pharmacology knowledge with real-world patient care. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| NSAIDs Part 3 – Test Prep and Practice Pearls; Nabumetone, Diclofenac, Meloxicam, Piroxicam, Etodolac, Indomethacin, Sulidac, and Ketorolac | 15 Oct 2026 | 00:14:49 | |
In this episode of Real Life Pharmacology, we take a closer look at several NSAIDs that are commonly encountered in clinical practice: nabumetone, diclofenac, meloxicam, piroxicam, etodolac, indomethacin, sulindac, and ketorolac. These medications may all belong to the same general class, but they have important differences in dosing, adverse effects, drug interactions, and clinical use. We’ll discuss which NSAIDs tend to be more COX-2 selective, which ones carry significant gastrointestinal or cardiovascular concerns, and why some agents are used much more cautiously than others. We’ll also cover practical pharmacology pearls for medications such as indomethacin, which is commonly used for acute gout, ketorolac, which is generally reserved for short-term pain management, and diclofenac, which has important cardiovascular considerations. Whether you’re studying for a pharmacology exam, working with patients, or simply want to strengthen your knowledge of NSAIDs, this episode focuses on the clinically relevant points you need to know about these eight medications. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| NSAIDs Part 2 – Test Prep and Practice Pearls for Aspirin, Ibuprofen, Naproxen, and Celecoxib | 08 Oct 2026 | 00:20:01 | |
Aspirin, ibuprofen, naproxen, and celecoxib are some of the most commonly used NSAIDs, but they are not interchangeable when it comes to safety, indications, and patient-specific risks. In this episode of Real Life Pharmacology, we compare these four medications and highlight the key differences pharmacists and other healthcare professionals need to know. We’ll review how NSAIDs work, including COX-1 and COX-2 inhibition, and discuss their effects on pain, inflammation, platelets, the gastrointestinal system, kidneys, cardiovascular system, and fluid balance. We’ll also compare the GI, cardiovascular, renal, and heart failure risks of aspirin, ibuprofen, naproxen, and celecoxib. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| NSAIDs Part 1 – Test Prep and Practice Pearls | 01 Oct 2026 | 00:24:47 | |
On this podcast episode, I cover the basics of NSAIDs, including how they work, what they are used for, significant drug interactions, and what adverse effects are important to monitor. I’ll educate about some of the major risks associated with NSAIDs and what I look out for as a practicing pharmacist. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Opioids Part 5 – Tramadol, Tapentadol, and Meperidine | 24 Sep 2026 | 00:16:19 | |
In this episode of Real Life Pharmacology, we’re taking a closer look at three unique opioids: tramadol, tapentadol, and meperidine. These medications have some important differences in their mechanisms, clinical uses, drug interactions, and safety concerns. We’ll review the key pharmacology and practical clinical pearls you should know when using these opioids in real-world practice. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Opioids Part 4 – Methadone and Buprenorphine | 17 Sep 2026 | 00:16:43 | |
In this episode of Real Life Pharmacology, we’re taking a closer look at two unique opioids: methadone and buprenorphine. Both medications have important roles in pain management and opioid use disorder, but their pharmacology, dosing, drug interactions, and safety considerations are quite different. We’ll review the key clinical pearls you need to know when using these medications in real-world practice. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Opioids Part 3 – Test Prep and Practice Pearls – Codeine and Fentanyl | 10 Sep 2026 | 00:20:30 | |
On this podcast episode, we will explore the most important practice pearls of codeine and fentanyl. Both medications are opioids, but codeine is frequently found in combination with acetaminophen. Fentanyl has numerous unique dosage forms, including the transdermal formulation which is a source of frequent test questions. I break these two medications down in this podcast episode. | |||
| Opioids Part 2 – Test Prep and Practice Pearls | 03 Sep 2026 | 00:12:53 | |
In Part 2 of my series on opioids, I cover hydromorphone, oxycodone, and oxymorphone. Hydromorphone and oxycodone are two opioids that are used frequently in clinical practice, and I will discuss what makes them unique, in addition to numerous other practice pearls and test prep nuggets. Enjoy the podcast and be sure to share it with friends, colleagues, and students! Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Opioids Part 1 – Test Prep and Practice Pearls | 27 Aug 2026 | 00:18:13 | |
On part 1 of opioids, I’ll discuss morphine, morphine equivalents, conversion, and hydrocodone. The pharmacokinetic differences will be important between opioids, as well as the dosage forms. I hope you enjoy this podcast episode and share it with your friends! Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Skeletal Muscle Relaxants – Test Prep and Practice Pearls | 20 Aug 2026 | 00:17:58 | |
On this episode of the Real Life Pharmacology podcast, I’m going to cover important practice pearls on skeletal muscle relaxants. Important medications that will be covered in this podcast include baclofen, cyclobenzaprine, tizanidine, and diazepam. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| GI Antispasmodics – Test Prep and Practice Pearls | 06 Aug 2026 | 00:17:55 | |
Abdominal cramping and intestinal spasms are common complaints in patients with conditions such as irritable bowel syndrome (IBS). Two of the most frequently prescribed medications for these symptoms are dicyclomine and hyoscyamine. These medications work by blocking muscarinic receptors, reducing smooth muscle contractions in the gastrointestinal tract and helping relieve painful spasms. While these medications can be effective, they are not without risks. Because of their anticholinergic effects, patients may experience dry mouth, constipation, blurred vision, dizziness, and urinary retention. Older adults are particularly susceptible to these adverse effects, making careful patient selection and monitoring especially important. Patients with benign prostatic hyperplasia (BPH), glaucoma, or cognitive impairment may be at higher risk for complications. In this episode of the Real Life Pharmacology podcast, we’ll review how dicyclomine and hyoscyamine work, discuss their most common clinical uses, compare their adverse effect profiles, and highlight practical education points to help optimize safe and effective use. Huge thank you to our sponsor – Mechanism of Action Podcast; Go check them out on all your favorite podcast platforms! Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Antacids – Test Prep and Practice Pearls | 30 Jul 2026 | 00:19:04 | |
Heartburn is one of the most common gastrointestinal complaints, and antacids remain a go-to option for fast symptom relief. In this episode, we’ll discuss how common antacids like calcium carbonate, magnesium hydroxide, aluminum hydroxide, and sodium bicarbonate work to neutralize stomach acid. We’ll also review their advantages, common adverse effects, important drug interactions, and considerations for patients with kidney disease. Whether you’re a healthcare professional looking for practical clinical pearls or simply want to better understand over-the-counter heartburn medications, this episode provides a concise overview of when antacids are appropriate—and when they may not be the best choice. Special thanks to the Mechanism of Action Podcast for sponsoring this episode – go check it out! Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Gastroparesis Medications – Test Prep and Practice Pearls | 23 Jul 2026 | 00:13:32 | |
Gastroparesis can be a frustrating condition for both patients and clinicians, with symptoms such as nausea, vomiting, early satiety, bloating, and poor glycemic control significantly affecting quality of life. Medication management often requires balancing effectiveness with safety, especially since many commonly prescribed drugs can either improve or worsen gastric emptying. In this episode of the Real Life Pharmacology podcast, we’ll review the medications used to treat gastroparesis, discuss their mechanisms of action, highlight important adverse effects, and identify medications that may contribute to or exacerbate delayed gastric emptying. Huge thank you to our sponsor – Mechanism of Action Podcast; Go check them out on all your favorite podcast platforms! Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| H2 Blockers – Test Prep and Practice Pearls | 16 Jul 2026 | 00:13:37 | |
H2 blockers may not receive as much attention as proton pump inhibitors, but they continue to play an important role in managing acid-related disorders. In this episode of the Real Life Pharmacology podcast, we’ll review how H2 blockers work, compare the available agents, discuss important adverse effects, renal dose adjustments, drug interactions, and identify the patients who are most likely to benefit from these medications. Whether you’re a pharmacist, nurse, pharmacy technician, physician, or student, this episode provides practical clinical pearls you can apply immediately to patient care. In this episode, I also discuss a new podcast I discovered – go check out the Mechanism of Action Podcast! It is an entertaining and educational look at how many of the medications used today were discovered and derived. | |||
| Proton Pump Inhibitors – Test Prep And Practice Pearls | 09 Jul 2026 | 00:18:49 | |
Proton pump inhibitors (PPIs) are among the most commonly prescribed medications, but understanding how they work is essential for using them safely and effectively. In this episode of the Real Life Pharmacology podcast, we’ll break down the pharmacology of PPIs, including their mechanism of action, common brand and generic names, clinical uses, adverse effects, drug interactions, and important monitoring considerations. Whether you’re a pharmacist, nurse, pharmacy technician, or student, this episode will help reinforce the key concepts you need to confidently apply PPI pharmacology in clinical practice. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Opioid Use Disorder Medications | 02 Jul 2026 | 00:17:25 | |
On this podcast episode, I cover commonly used medications for opioid use disorder. Buprenorphine, methadone, and naltrexone are all potential options in OUD. I’ll discuss the pharmacology of each medication and the most common practice pearls that will show up in practice and on your board exams. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Alcohol Use Disorder Medications | 25 Jun 2026 | 00:14:38 | |
Naltrexone is often a first-line medication for AUD. It works as an opioid receptor antagonist, reducing the rewarding effects of alcohol and decreasing cravings. Patients frequently report that alcohol becomes less pleasurable while taking the medication. Oral naltrexone is typically dosed at 50 mg daily, while a long-acting injectable formulation is also available. Avoid use in patients taking opioids and use caution in significant liver dysfunction. Acamprosate helps maintain abstinence by modulating glutamate and GABA neurotransmission. Chronic alcohol use disrupts the balance between excitatory and inhibitory pathways in the brain, and acamprosate helps restore equilibrium. It is primarily eliminated renally, making it a useful option in patients with liver disease. The most common adverse effect is diarrhea. Disulfiram works through a completely different mechanism. It inhibits aldehyde dehydrogenase, causing acetaldehyde accumulation when alcohol is consumed. This can lead to flushing, nausea, vomiting, headache, and hypotension. Because of this aversive reaction, patient motivation and adherence are critical for success. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Monoamine Oxidase Inhibitors – Test Prep and Practice Pearls | 18 Jun 2026 | 00:14:33 | |
In this episode, we explore monoamine oxidase inhibitors (MAOIs), one of the oldest yet most effective classes of antidepressants. We discuss how MAOIs such as phenelzine, tranylcypromine, isocarboxazid, and selegiline work by increasing serotonin, norepinephrine, and dopamine levels in the brain. The episode reviews their unique role in treatment-resistant and atypical depression, key adverse effects, important dietary considerations involving tyramine-containing foods, and potentially serious drug interactions. We also highlight practical clinical pearls to help pharmacists and healthcare professionals safely and effectively use these powerful but often underutilized medications. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Insomnia Medications – 6.2 Nursing Pharmacology Review Course | 15 Jun 2026 | 00:13:35 | |
I cover the most important insomnia medications. We cover adverse effects, drug monitoring, and much more. You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com! | |||
| Antidepressants: Trazodone, Nefazodone, Vilazodone, and Vortioxetine – Test Prep and Practice Pearls | 11 Jun 2026 | 00:14:50 | |
In this episode, we explore four unique antidepressants that do not fit neatly into the traditional SSRI or SNRI categories: trazodone, nefazodone, vilazodone, and vortioxetine. Trazodone and nefazodone are classified as serotonin antagonist and reuptake inhibitors (SARIs), working primarily through blockade of 5-HT2 receptors while also inhibiting serotonin reuptake. Trazodone’s strong antihistamine and alpha-1 blocking properties make it highly sedating and commonly used off-label for insomnia, whereas nefazodone causes less sedation but is rarely prescribed today because of its association with severe and potentially fatal liver toxicity. Both agents are notable for producing less sexual dysfunction than many traditional SSRIs. We also discuss two newer multimodal antidepressants: vilazodone (Viibryd) and vortioxetine (Trintellix). Vilazodone combines serotonin reuptake inhibition with partial agonism at the 5-HT1A receptor, a mechanism often compared to combining an SSRI with buspirone. Vortioxetine has an even more complex pharmacology, acting as a serotonin reuptake inhibitor while modulating multiple serotonin receptor subtypes through agonist, partial agonist, and antagonist actions. This multimodal activity may contribute to benefits in cognitive symptoms associated with major depressive disorder. Throughout the episode, we compare receptor pharmacology, clinical applications, adverse effect profiles, and the unique characteristics that distinguish these medications from more commonly prescribed antidepressants. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| ICU Sedation – 6.1 Nursing Pharmacology Review Course | 08 Jun 2026 | 00:12:21 | |
In this section, I educate about the most common ICU sedation medications. You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com! | |||
| SNRIs – Test Prep and Practice Pearls | 04 Jun 2026 | 00:15:10 | |
Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressants that increase serotonin and norepinephrine levels in the brain. Common agents include venlafaxine (Effexor XR), desvenlafaxine (Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), and milnacipran (Savella). In addition to treating depression and anxiety disorders, several SNRIs have important pain indications, making them especially useful in patients with neuropathy, fibromyalgia, or chronic musculoskeletal pain. Common adverse effects include nausea, sweating, insomnia, sexual dysfunction, and elevated blood pressure. Clinicians should also remember the significant discontinuation risk associated with shorter half-life agents like venlafaxine and desvenlafaxine. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Infectious Disease Section 5.4 – HIV Medications | 01 Jun 2026 | 00:18:34 | |
Human Immunodeficiency Virus, or HIV, remains one of the most important infectious diseases in modern healthcare, but advances in antiretroviral therapy have transformed it from a fatal diagnosis into a manageable chronic condition for many patients. In this episode, we’ll break down the major medication classes used to treat HIV, discuss how these drugs work, review key adverse effects and drug interactions, and highlight practical nursing considerations that impact patient safety and adherence. Whether you work in acute care, outpatient practice, long-term care, or public health, understanding HIV pharmacology is essential to providing compassionate, evidence-based care for patients living with HIV and AIDS. You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com! | |||
| Mirtazapine and Bupropion – Test Prep and Practice Pearls | 28 May 2026 | 00:14:44 | |
Mirtazapine is a unique antidepressant often chosen when depression occurs alongside insomnia or poor appetite. Its antihistamine activity makes it sedating, particularly at lower doses, and it commonly increases appetite and weight. Unlike many SSRIs, mirtazapine has a lower risk of sexual dysfunction and gastrointestinal side effects because it blocks 5-HT2 and 5-HT3 receptors. It is frequently dosed at bedtime and can be especially useful in older adults or medically ill patients who need both mood improvement and help with sleep or weight gain. Bupropion is an activating antidepressant that works by increasing norepinephrine and dopamine activity rather than serotonin. It is often preferred in patients with fatigue, low motivation, hypersomnia, or concerns about sexual dysfunction and weight gain. Bupropion is also approved for smoking cessation. Common adverse effects include insomnia, anxiety, dry mouth, and headache. A major clinical pearl is its dose-related seizure risk, making it contraindicated in patients with seizure disorders or eating disorders such as anorexia nervosa or bulimia. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Infectious Disease Section 5.3- Antifungal Agents | 25 May 2026 | 00:17:06 | |
Fungal infections are commonly encountered across healthcare settings, ranging from oral thrush and vaginal yeast infections to serious systemic infections in critically ill patients. In this episode, we’ll review the major antifungal medications nurses should know, including azoles, echinocandins, polyenes, and topical antifungals. We’ll focus on practical nursing considerations such as monitoring for adverse effects, recognizing important drug interactions, administration tips, and patient education points. By the end of the episode, listeners will have a stronger understanding of how antifungal medications work and how nurses play a key role in ensuring safe and effective treatment. You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com! | |||
| Tricyclic Antidepressants – Test Prep and Practice Pearls | 21 May 2026 | 00:17:01 | |
Welcome to today’s episode on the tricyclic antidepressants, commonly known as TCAs — one of the foundational medication classes in psychopharmacology. Although newer antidepressants like SSRIs often dominate modern prescribing, TCAs remain highly relevant in clinical practice because of their effectiveness in treatment-resistant depression, chronic pain syndromes, migraine prevention, insomnia, and certain anxiety disorders. In this episode, we’ll break down the pharmacology behind these medications, discuss how tertiary amines differ from secondary amines, review major adverse effects and drug interactions, and highlight the key clinical pearls that healthcare professionals and students need to know. Whether you’re a medical, pharmacy, nursing, or PA student preparing for exams, or a practicing clinician looking for a practical refresher, this episode will give you a solid framework for understanding this classic but still clinically important medication class. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Infectious Disease Section 5.2- Antiviral Agents | 18 May 2026 | 00:15:28 | |
This nursing pharmacology review covers the essential antiviral medications commonly encountered in clinical practice and on nursing exams. The video explains how antiviral drugs work, what infections they treat, and the key nursing considerations for safe medication administration and monitoring. Major medications discussed may include acyclovir, valacyclovir, oseltamivir, antiretroviral therapy, and other commonly prescribed agents. You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com! | |||
| SSRIs Test Prep and Practice Pearls – Part 2 | 14 May 2026 | 00:14:41 | |
SSRI adverse effects are critical to know. In part 2 of this 2-part series on SSRIs, we cover the most important adverse effects to know, in addition to putting a nice bow on the most important clinical practice pearls on each SSRI. Enjoy the show! Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Infectious Disease Section 5.1- Antibiotics | 11 May 2026 | 00:42:37 | |
This nursing pharmacology review provides a high-yield overview of the most important antibiotic classes used in clinical practice. The video explains how common antibiotics work, what infections they treat, and the major nursing considerations associated with each class. Key topics include penicillins, cephalosporins, macrolides, fluoroquinolones, tetracyclines, vancomycin, aminoglycosides, and sulfonamides. Emphasis is placed on side effects, black box warnings, allergy considerations, renal dosing, patient counseling, and critical monitoring parameters nurses should recognize in both inpatient and outpatient settings. You can find the full 16+ hour nursing pharmacology review course, including PDF handouts, cheat sheets, practice questions, and on-demand videos at meded101.com! | |||
| SSRIs – Test Prep and Practice Pearls Part 1 | 07 May 2026 | 00:23:51 | |
In this episode, we break down the pharmacology of selective serotonin reuptake inhibitors (SSRIs) with a focus on the high-yield clinical pearls pharmacists, medical students, and healthcare professionals need to know. We compare the major SSRIs—including fluoxetine, sertraline, paroxetine, citalopram, escitalopram, and fluvoxamine—based on adverse effects, drug interactions, pharmacokinetics, and board exam relevance. Topics include serotonin syndrome, discontinuation syndrome, CYP450 interactions, QT prolongation, sexual dysfunction, weight changes, and SSRI selection in special populations such as older adults and pregnancy. Whether you are preparing for exams, clinical rotations, or looking to sharpen your psychopharmacology knowledge, this episode provides practical and memorable insights into one of the most commonly prescribed medication classes. This is Part 1 of 2. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Thyroid Disorders – Section 4.5 – Free Nursing Pharmacology Review Course From Meded101 | 04 May 2026 | 00:15:50 | |
This podcast episode gives nurses a practical, easy-to-apply overview of common thyroid disorders, focusing on how to recognize and manage both hypothyroidism and hyperthyroidism in clinical practice. It reviews key differences in presentation—such as fatigue, weight gain, and cold intolerance in hypothyroidism versus weight loss, tachycardia, and heat intolerance in hyperthyroidism—while connecting these symptoms to underlying physiology. Nurses will learn important medication considerations, including proper administration of levothyroxine and monitoring for adverse effects with methimazole. The episode also highlights critical safety topics like recognizing thyroid storm, interpreting lab values (TSH, T3, T4), and providing effective patient education. With real-world clinical pearls, this episode helps nurses build confidence in managing thyroid conditions across care settings. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Real Life Examples: Polypharmacy and the Prescribing Cascade Part 2 of 2 | 30 Apr 2026 | 00:14:32 | |
Polypharmacy is one of the most common—and often overlooked—challenges in modern healthcare, especially in older adults. It’s not just about the number of medications a patient is taking, but whether each one still has a clear indication, is providing benefit, and isn’t causing harm. As medication lists grow, so does the risk of adverse effects, drug interactions, and something we see all the time in practice: the prescribing cascade. A prescribing cascade happens when a medication causes a side effect that is misinterpreted as a new medical condition, leading to the addition of another drug. Over time, this can snowball into unnecessary complexity and increased risk for patients. In part 2 of this podcast, we outline 5 more examples that I’ve encountered in my geriatric pharmacist practice. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Insulin Therapy Section 4.4 – Free Nursing Pharmacology Review Course | 27 Apr 2026 | 00:18:11 | |
This podcast episode gives nurses a practical, bedside-focused guide to insulin therapy, helping simplify one of the most important—and often confusing—areas of diabetes management. It reviews key insulin types, including rapid-acting insulin lispro, long-acting insulin glargine, and intermediate options like NPH insulin, highlighting onset, peak, and duration differences that drive dosing decisions. Nurses will learn how to safely administer insulin, adjust for meals and blood glucose trends, and recognize and treat hypoglycemia quickly. Real-world clinical tips are included to help nurses feel confident managing insulin in both inpatient and outpatient settings. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Real Life Examples: Polypharmacy and the Prescribing Cascade Part 1 of 2 | 23 Apr 2026 | 00:11:32 | |
Polypharmacy isn’t just about medication count—it’s about cumulative risk and unintended consequences. One of the biggest drivers is the prescribing cascade, where a drug side effect is mistaken for a new condition, and another medication gets added instead of addressing the root cause. You see this all the time in practice. A patient starts amlodipine and develops edema, then gets placed on furosemide. Or donepezil leads to urinary symptoms, and oxybutynin is added—potentially worsening cognition. These patterns add risk quickly. In this episode, I’ll break down common examples that I have recently encountered in practice. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Diabetes Medications Section 4.3 – Free Nursing Pharmacology Review Course | 20 Apr 2026 | 00:21:54 | |
This podcast episode provides nurses with a clear, practical overview of non-insulin diabetes medications, focusing on how to safely and effectively manage patients with type 2 diabetes. It reviews key drug classes such as metformin, glipizide, empagliflozin, and semaglutide, emphasizing mechanisms of action, common side effects, and important monitoring parameters. Nurses will learn how to recognize risks like hypoglycemia with sulfonylureas, genitourinary infections with SGLT2 inhibitors, and gastrointestinal effects with GLP-1 agents, along with key patient counseling points. The episode also connects medication selection to real-world considerations such as weight impact, cardiovascular benefit, and kidney function, helping nurses feel more confident in supporting individualized diabetes care. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Heart Failure Medications – Loops, SGLT2s, and ARNI – Test Prep and Practice Pearls | 16 Apr 2026 | 00:16:59 | |
If you’re managing patients with heart failure, you already know the medication landscape has evolved quickly over the past decade. From traditional volume management with furosemide to newer, guideline-driven therapies like sacubitril/valsartan and empagliflozin, staying up to date is essential—but not always easy. In this episode, we break down three cornerstone medication classes you’ll encounter every day in practice: loop diuretics, ARNI therapy, and SGLT2 inhibitors. We start with the fundamentals of loop diuretics—how they work, when to use them, and key monitoring parameters—before shifting into the mortality-reducing benefits of ARNI therapy. Finally, we explore the rapidly expanding role of SGLT2 inhibitors, which have transformed both heart failure and chronic kidney disease management. Whether you’re a pharmacist, nurse, or student, this episode focuses on practical, real-world application. We highlight clinical pearls, common pitfalls, and monitoring strategies to help you feel more confident when optimizing therapy. Tune in to sharpen your understanding of these essential therapies and walk away with actionable insights you can use right away in patient care. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Diabetes Compelling Indications Section 4.2 – Free Nursing Pharmacology Review Course | 13 Apr 2026 | 00:16:17 | |
This podcast episode breaks down diabetes “compelling indications” in a way that’s highly practical for nurses managing complex patients. It explains how comorbid conditions like cardiovascular disease, heart failure, and chronic kidney disease influence medication selection beyond just lowering A1c. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Medication Errors – Real Life Examples and Definitions – Part 2 | 09 Apr 2026 | 00:17:27 | |
In this section, I cover the most important medication errors you’ll see in practice. I got a good start in Part 1, so go back and listen to that for some great real-life information. In this section, I talk about a few types of medication errors that have led to serious complications and life-threatening situations for our patients. Wrong patient errors are one of the highest risk errors that a healthcare professional can make, and I cover that in this podcast episode. I hope you find this episode on medication errors helpful, and if you do, I’d greatly appreciate a rating and review on iTunes or whatever platform you listen on – Thanks! Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Addison’s and Cushing’s Disease Section 4.1 – Nursing Pharmacology Review Course | 06 Apr 2026 | 00:09:18 | |
This podcast episode provides nurses with a practical, clinically focused overview of Addison’s disease and Cushing’s disease, highlighting key differences in pathophysiology, presentation, and management. Listeners will learn how adrenal insufficiency in Addison’s leads to symptoms like fatigue, hypotension, and hyperpigmentation, while excess cortisol in Cushing’s presents with weight gain, hypertension, and glucose intolerance. The episode emphasizes important nursing considerations such as recognizing adrenal crisis, monitoring electrolytes and blood pressure, patient education on steroid adherence, and identifying medication-related causes of Cushing’s. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Medication Errors – Real Life Examples and Definitions – Part 1 | 02 Apr 2026 | 00:13:43 | |
In this 2 part series, I cover important medication errors, including examples I’ve seen in real life. Some of the error types covered in section 1 include:
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Respiratory Failure Section 3.3 – Free Nursing Pharmacology Review Course | 30 Mar 2026 | 00:14:16 | |
Respiratory failure is a serious clinical condition that nurses frequently encounter in critical care, emergency, and acute care settings. While supportive therapies such as oxygen and mechanical ventilation are often required, medications also play an important role in stabilizing patients and addressing the underlying causes. In this episode, we’ll review the general pharmacologic strategies used in the management of respiratory failure and highlight key considerations for nursing practice. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Aminoglycosides Podcast – Pharmacology, Kinetics, Monitoring, and Adverse Effect | 26 Mar 2026 | 00:22:20 | |
Aminoglycosides are antibiotics used to treat serious Gram-negative infections, but they also come with important safety concerns and unique pharmacokinetic properties that healthcare professionals must understand. In this episode, we’re going to break down the essential clinical pearls surrounding aminoglycosides and how pharmacists and clinicians can use them effectively while minimizing toxicity. We’ll review the most common agents in this class, including Gentamicin, Tobramycin, and Amikacin, and discuss when these medications are typically used in clinical practice. From severe Gram-negative infections to synergy dosing in conditions like infective endocarditis, aminoglycosides still play a role in antimicrobial therapy. Another key focus of this episode will be the pharmacology that makes these drugs unique. Aminoglycosides demonstrate concentration-dependent killing and a post-antibiotic effect, which is why strategies like extended-interval dosing and tools such as the Hartford Nomogram are commonly used to guide therapy. We’ll also cover the major adverse effects, including nephrotoxicity and ototoxicity, and highlight practical monitoring strategies to help reduce these risks. By the end of this episode, you’ll have a clearer understanding of how aminoglycosides work, when they should be used, and the key dosing and monitoring principles that every clinician should know. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| COPD Section 3.2 – Free Nursing Pharmacology Review Course | 23 Mar 2026 | 00:21:48 | |
Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory condition that nurses encounter frequently in both inpatient and outpatient settings. Effective pharmacologic management plays a major role in controlling symptoms, preventing exacerbations, and improving quality of life for patients living with COPD. In this episode, we’ll review the key medication classes used to manage COPD and highlight practical clinical considerations nurses should know when caring for these patients. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Vancomycin Podcast – Pharmacology, Adverse Effects, and Monitoring | 19 Mar 2026 | 00:26:37 | |
In this episode, we are going to take a closer look at Vancomycin, one of the most widely used antibiotics in the hospital setting and a medication that pharmacists frequently monitor. Vancomycin is a glycopeptide antibiotic primarily used to treat serious gram-positive infections, including those caused by Methicillin-resistant Staphylococcus aureus (MRSA). Its mechanism of action involves inhibiting bacterial cell wall synthesis by binding to the D-alanine–D-alanine portion of peptidoglycan precursors, which ultimately prevents the bacteria from forming a stable cell wall. Clinically, vancomycin is commonly used for infections such as bacteremia, endocarditis, osteomyelitis, and severe skin and soft tissue infections when resistant gram-positive organisms are suspected. One of the most important aspects of vancomycin therapy is therapeutic drug monitoring, as maintaining appropriate exposure is critical for both efficacy and safety. Current practice often focuses on achieving target AUC-to-MIC ratios rather than relying solely on trough levels. Pharmacists also play an important role in adjusting doses based on renal function and monitoring for adverse effects. Two key safety concerns with vancomycin are nephrotoxicity and vancomycin infusion-related reactions such as “red man syndrome,” which is characterized by flushing, rash, and hypotension if the medication is infused too rapidly. Throughout this episode, we will review the pharmacology, monitoring parameters, and clinical pearls that healthcare professionals should understand when managing patients receiving vancomycin therapy. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Asthma Section 3.1 – Free Nursing Pharmacology Review Course | 16 Mar 2026 | 00:23:13 | |
Asthma is a common chronic respiratory condition that nurses frequently encounter in both outpatient and inpatient settings. Effective medication management is essential for controlling symptoms, preventing exacerbations, and improving long-term respiratory health. In this episode, we’ll review the major medication classes used to manage asthma and highlight key nursing considerations when caring for patients with this condition. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! | |||
| Antiarrhythmic Drugs Part 2 | 12 Mar 2026 | 00:14:00 | |
In this episode, we are going to review antiarrhythmic drugs that clinicians may encounter in practice: Digoxin, Propafenone, Dofetilide, and a few others. While these drugs are commonly used in the management of atrial fibrillation and other rhythm disturbances, they each come with important pharmacology and safety considerations that pharmacists and healthcare providers need to recognize. Digoxin is a cardiac glycoside that increases contractility while also slowing AV node conduction through enhanced vagal tone, making it useful for rate control in atrial fibrillation, particularly in patients with heart failure. However, it has a narrow therapeutic index, and toxicity can occur if renal function declines or electrolyte abnormalities develop. Propafenone is a Class IC sodium channel blocker used primarily for rhythm control in atrial fibrillation. A key clinical pearl with this medication is that it should generally be avoided in patients with structural heart disease due to the risk of proarrhythmia. Dofetilide and sotalol are both Class III antiarrhythmics that work by blocking potassium channels and prolonging cardiac repolarization. Because of their ability to prolong the QT interval, both agents carry a risk of torsades de pointes and require careful monitoring. Dofetilide initiation typically requires hospitalization to monitor the QT interval and adjust dosing based on renal function. Sotalol also requires attention to renal function and ECG monitoring, and it has additional beta-blocking effects that can contribute to bradycardia and fatigue. Throughout this episode, we will break down the mechanisms, common clinical uses, and key safety pearls for these medications to help you better understand how they fit into arrhythmia management. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Antiarrhythmic Medications Part 1 – Test Prep and Practice Pearls | 05 Mar 2026 | 00:17:37 | |
Antiarrhythmic medications are some of the most complex and high-risk drugs pharmacists encounter in clinical practice. In this episode, we break down the most important concepts pharmacists need to understand about antiarrhythmics, including the major drug classes and the clinical situations where these medications are commonly used. A major focus of the discussion is medication safety. Many antiarrhythmics carry risks such as QT prolongation, proarrhythmia, and significant drug–drug interactions. Pharmacists play a critical role in identifying these risks, monitoring electrolytes and ECG changes, and recognizing situations where therapy adjustments are necessary. We also highlight why certain medications require inpatient initiation and careful monitoring. The episode also covers practical clinical pearls, including the unique toxicity profile and interaction potential of amiodarone, how to think about rate control versus rhythm control strategies in atrial fibrillation, and the most common medication-related problems pharmacists should watch for. Whether practicing in ambulatory care, hospital, or long-term care settings, understanding antiarrhythmics can help pharmacists prevent serious complications and improve patient outcomes. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||
| Antiplatelet Agents: P2Y12 Inhibitors – Test Prep and Practice Pearls | 26 Feb 2026 | 00:19:16 | |
P2Y12 inhibitors are a cornerstone of antiplatelet therapy in cardiovascular disease. These agents block the P2Y12 receptor on platelets, preventing ADP-mediated activation and reducing platelet aggregation. By inhibiting this amplification pathway, they help prevent arterial thrombosis in conditions such as acute coronary syndrome, percutaneous coronary intervention, stroke, and peripheral artery disease. The most commonly used oral agents include clopidogrel, prasugrel, and ticagrelor, each with important pharmacokinetic and clinical differences that influence agent selection. From a pharmacist’s perspective, choosing the right P2Y12 inhibitor requires balancing ischemic benefit with bleeding risk. Clopidogrel requires CYP2C19 activation and is subject to drug interactions and genetic variability. Prasugrel provides more potent inhibition but carries a higher bleeding risk and is contraindicated in patients with prior stroke or TIA. Ticagrelor offers reversible inhibition but comes with unique considerations such as dyspnea and drug interactions via CYP3A4. Understanding these nuances allows pharmacists to optimize dual antiplatelet therapy and improve patient outcomes. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources!Nursing Pharmacology Review Course Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101 Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating | |||