POLITICO's Off Message – Details, episodes & analysis

“If we miss this opportunity, God help us.” Joe Manchin and Lisa Murkowski. Two moderate senators smack in the middle — and on either side — of a split 50-50 Senate. On our first episode of Playbook Deep Dive, the two friends open up in a rare interview with POLITICO’s Burgess Everett. They get personal: about reconciliation, frustration over the Senate’s hurdles — even why Murkowski hogs the best fishing holes. And Manchin reveals a major endorsement, heard first on this show.Subscribe to our new weekly politics show, Playbook Deep Dive, wherever you listen to podcasts.Rachael Bade is a co-author of POLITICO Playbook.Burgess Everett is co-congressional bureau chief at POLITICO.Adrienne Hurst is a producer for POLITICO audio.Annie Rees is a producer for POLITICO audio.Jenny Ament is senior producer for POLITICO audio.Irene Noguchi is the executive producer of POLITICO audio. Special thanks to Elana Schor, Anthony Adragna and Ben LefebvreSHOW NOTES Democrat Manchin backs Republican Murkowski's reelection, by Burgess Everett Learn more about your ad choices. Visit megaphone.fm/adchoices

Presenting a sponsored episode of “Global Translations”: Over the past year, businesses, employees and families across the globe were forced to rethink what it means to “go to work.” Now, with the COVID-19 vaccine rollout underway, many corporate leaders are focused on ensuring the return to work is equitable for all employees. Learn more about your ad choices. Visit megaphone.fm/adchoices

"Off Message" presents the second episode of the new season of POLITICO's podcast "Global Translations": Once there is a working Covid vaccine, manufacturers across the globe will need to scale up production to produce billions of doses — meaning billions of pharmaceutical-grade glass vials, rubber stoppers, packaging and storage and refrigeration. In a special airing of POLITICO's Global Translations podcast, hosts Luiza Savage and Ryan Heath look at the challenges of making enough vaccines for the world.Luiza Savage is the host of "Global Translations"Ryan Heath is a host of "Global Translations"Annie Rees is a producer for POLITICO AudioKara Tabor is a producer for POLITICO AudioJenny Ament is the senior producer for POLITICO AudioIrene Noguchi is the executive producer of POLITICO AudioSarah Owermohle is a POLITICO health reporter covering vaccines. Dr. Anthony Fauci is the director of the National Institute of Allergy and Infectious Diseases.Jim Robinson is a former MERCK executive (manufacturing lead for ebola project); currently with CEPI (Coalition for Epidemic Preparedness Innovations).Dan Diamond is a POLITICO health care reporter and the host of the "Pulse Check" podcast and newsletter. Check out and subscribe to POLITICO's Global Translations, POLITICO Pulse, and Global Pulse newsletters. Read Luiza Savage's article on why nationalism is the next big challenge for Covid-19 vaccines. Global Translations newsletter: https://www.politico.com/newsletters/global-translationsPOLITICO Pulse newsletter: https://www.politico.com/politicopulse/Global Pulse newsletter: https://www.politico.com/newsletters/global-pulsePOLITICO article: "The next vaccine challenge: Nationalism": https://www.politico.com/news/2020/10/28/covid-vaccine-challenge-nationalism-433023 Learn more about your ad choices. Visit megaphone.fm/adchoices

Human Rights Campaign president Chad Griffin assesses the record of Trump White House--and Ivanka Trump--on gay rights and what the Resistance has to learn. Tony-nominated Paula Vogel talks her play "Indecent" and anxieties about art in the age of Trump. Learn more about your ad choices. Visit megaphone.fm/adchoices

Small Business Administrator Linda McMahon discusses going from bankruptcy to WWE millions, the first time she met Donald Trump, staffing challenges and her mission to introduce more small business owners to the SBA. Learn more about your ad choices. Visit megaphone.fm/adchoices

Wyclef Jean’s advice for celebrities who want to get political: Don’t be like Kathy Griffin.Read up, said the musician of Fugees fame, and one-time aspiring celebrity-turned-president himself. And if you’re a high-profile person, think about how what you’re doing and saying might be interpreted, or maybe misinterpreted. Learn more about your ad choices. Visit megaphone.fm/adchoices

Mention President Donald Trump’s name and Nebraska Senator Ben Sasse closes his eyes, rocks back and forth on his heels in almost momentary pinched smile meditation, waiting for it to pass.He never liked Trump. He still doesn’t like Trump. And now that he’s promoting his new book, “The Vanishing American Adult,” he doesn’t want to talk about the American president’s not counting as an adult according to the principles he spends 300 pages laying out. Learn more about your ad choices. Visit megaphone.fm/adchoices

Rep. Tom Reed and Rep. Josh Gottheimer say that President Trump can get the biggest tax reform package in history done in conjunction with the largest infrastructure package, and that he can get it through with bipartisan support by early 2018. Reed and Gottheimer aren’t crazy—they’re the co-chairs of the bipartisan Problem Solvers Caucus, and they insist their day has come. The voters who elected Trump demand it. Learn more about your ad choices. Visit megaphone.fm/adchoices

L.A. Mayor Eric Garcetti sits down with Isaac Dovere to discuss his relationship with Donald Trump, what he learned about politics from his father and what his hopes are for his own political career. Plus, Isaac is joined by California Playbook author Carla Marinucci for insight into Garcetti's possible career moves. Learn more about your ad choices. Visit megaphone.fm/adchoices

Chicago Mayor Rahm Emanuel believes everyone in Washington is too focused on the craze around President Trump and unable to see what’s actually going on—and what’s not. Emanuel says that “America’s word and America’s reliability is now in question,” and the turmoil and drama surrounding the West Wing has over shadowed major events like the proposed upheaval to the tax code, mounting tensions with North Korea and Oval Office invites for anti-democratic leaders. Learn more about your ad choices. Visit megaphone.fm/adchoices