Explore every episode of the podcast Out of the Blue: An AJRCCM Podcast
| Title | Pub. Date | Duration | |
|---|---|---|---|
| Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline | 18 juin 2026 | 00:30:34 | |
Dr. John Fleetham chats with Dr. Barbara Jones about her ATS guideline, "Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline." | |||
| Outcomes of a Typical Fibrotic Hypersensitivity Pneumonitis Pattern on Chest Computed Tomography and Rethinking the Computed Tomography and Histopathological Nomenclature of Hypersensitivity Pneumonitis | 28 mai 2026 | 00:33:24 | |
Dr. Mohleen Kang speaks with Dr. Chris Ryerson, Dr. Johannson, and Dr. Fernández Pérez about their papers, "Outcomes of a Typical Fibrotic Hypersensitivity Pneumonitis Pattern on Chest Computed Tomography" and "Rethinking the Computed Tomography and Histopathological Nomenclature of Hypersensitivity Pneumonitis: Unveiling Bronchiolocentric Patterns of Interstitial Pneumonia." | |||
| The Effectiveness of Isoniazid Preventive Treatment Among Contacts of Multidrug-Resistant Tuberculosis: A Systematic Review and Individual-Participant Meta-Analysis | 14 mai 2026 | 00:34:35 | |
Dr. John Fleetham speaks with Dr. Leonardo Martinez about his article, "The Effectiveness of Isoniazid Preventive Treatment Among Contacts of Multidrug-Resistant Tuberculosis: A Systematic Review and Individual-Participant Meta-Analysis." | |||
| Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3) | 30 avr. 2026 | 00:35:19 | |
Dr. Michael Lanspa chats with Dr. Ewan Goligher about his article, "Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3)." | |||
| Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease | 23 avr. 2026 | 00:46:17 | |
Dr. Mohleen Kang chats with Dr. Kerri Johannson and Dr. Tamera Corte about their article, "Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease." | |||
| Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline | 26 mars 2026 | 00:16:39 | |
Dr. John Fleetham chats with Dr. Sonal Munsiff and Dr. Raquel Duarte about their article, "Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline." | |||
| “Social Apnea”: Obstructive Sleep Apnea Is Exacerbated on Weekends | 26 févr. 2026 | 00:22:31 | |
Dr. John Fleetham chats with Danny Eckert about his article, "Obstructive Sleep Apnea is Exacerbated on Weekends." | |||
| A Quantitative Imaging Measure of Progressive Pulmonary Fibrosis and One-Year Change in Quantitative Computed Tomography Is Associated with Meaningful Outcomes in Fibrotic Lung Disease | 19 févr. 2026 | 00:48:04 | |
Dr. Mohleen Kang chats with Dr. Stephen Humphries, Dr. Matthew Koslow, Dr. Justin Oldham, Dr. Jennifer Wang, Alexander Bankier, and Dr. David Baraghoshi about their articles, "A Quantitative Imaging Measure of Progressive Pulmonary Fibrosis" and "One-Year Change in Quantitative Computed Tomography Is Associated with Meaningful Outcomes in Fibrotic Lung Disease." | |||
| Host-Microbe Multiomic Profiling Predicts Mortality in Sepsis | 05 févr. 2026 | 00:30:04 | |
Dr. Michael Lanspa chats with Dr. Natasha Spottiswoode and Chaz Langelier about their article, "Host-Microbe Multiomic Profiling Predicts Mortality in Sepsis." | |||
| Inhalable Textile Microplastic Fibers Impair Airway Epithelial Differentiation and Inhaled Microplastics and Airway Development: Concerning Evidence from Organoids | 29 janv. 2026 | 00:25:59 | |
Dr. John Fleetham chats with Dr. Barbro N Melgert and Dr. Chris Carlsten about their articles, "Inhalable Textile Microplastic Fibers Impair Airway Epithelial Differentiation" and "Inhaled Microplastics and Airway Development: Concerning Evidence from Organoids." | |||
| Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial | 27 nov. 2025 | 00:17:14 | |
Dr Michael Lanspa chats with Dr. Imeen van der Wal and Dr. Chloe Grim on their article, "Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial." | |||
| Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline | 13 nov. 2025 | 00:30:34 | |
Dr. John Fleetham chats with Dr. Barbara Jones about her ATS guideline, "Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline." | |||
| Is CT Screening For Lung Cancer Generalizable to Older Patients? | 06 nov. 2025 | 00:38:07 | |
In this podcast, we review a comparison of outcomes in patients 65-74 years old from SEER-Medicare and NLST datasets in stage I lung cancer with study first author, Dr. Nichole Tanner as well as Dr. Neal Navani. | |||
| Outcomes of a Typical Fibrotic Hypersensitivity Pneumonitis Pattern on Chest Computed Tomography and Rethinking the Computed Tomography and Histopathological Nomenclature of Hypersensitivity Pneumonitis | 09 oct. 2025 | 00:33:24 | |
Dr. Mohleen Kang chats with Dr. Chris Ryerson, Dr. Johannson, and Dr. Fernández Pérez about their papers, "Outcomes of a Typical Fibrotic Hypersensitivity Pneumonitis Pattern on Chest Computed Tomography" and "Rethinking the Computed Tomography and Histopathological Nomenclature of Hypersensitivity Pneumonitis: Unveiling Bronchiolocentric Patterns of Interstitial Pneumonia." | |||
| Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3) | 11 sept. 2025 | 00:35:19 | |
Dr. Michael Lanspa chats with Dr. Ewan Goligher about his article, "Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3)." | |||
| Performance Characteristics for Physiological Measures of Progressive Pulmonary Fibrosis and Progress in Progressive Pulmonary Fibrosis | 04 sept. 2025 | 00:21:24 | |
Dr. Mohleen Kang chats with Dr. Justin Oldham, Dr. Chad Newton and Dr. Jesse Roman about their papers, "Performance Characteristics for Physiological Measures of Progressive Pulmonary Fibrosis" and "Progress in Progressive Pulmonary Fibrosis." | |||
| A New Global Definition of Acute Respiratory Distress Syndrome | 28 août 2025 | 00:33:36 | |
Dr. Michael Lanspa chats with Dr. Michael Matthay about his article, "A New Global Definition of Acute Respiratory Distress Syndrome." | |||
| Epidemiology and Prognostic Significance of Cough in Fibrotic Interstitial Lung Disease | 21 août 2025 | 00:21:32 | |
Dr. John Fleetham chats with Dr. Chris Ryerson and Dr. Yet Khor about their article, "Epidemiology and Prognostic Significance of Cough in Fibrotic Interstitial Lung Disease." | |||
| Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease | 31 juil. 2025 | 00:46:17 | |
Dr. Mohleen Kang chats with Dr. Kerri Johannson and Dr. Tamera Corte about their article, "Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease." | |||
| Approach to the Evaluation and Management of Interstitial Lung Abnormalities | 17 juil. 2025 | 00:30:28 | |
Dr. Mohleen Kang chats with Dr. Anna Podolanczuk and Dr. Gary Hunninghake about their article, "Approach to the Evaluation and Management of Interstitial Lung Abnormalities." | |||
| Camlipixant in Refractory Chronic Cough: A Phase 2b, Randomized, Placebo-controlled Trial (SOOTHE)" and "Camlipixant: A New Hope for Refractory Chronic Cough? | 10 juil. 2025 | 00:28:51 | |
Dr. John Fleetham chats with Dr. Jaclyn Smith and Dr. Imran Satia about their articles, "Camlipixant in Refractory Chronic Cough: A Phase 2b, Randomized, Placebo-controlled Trial (SOOTHE)" and "Camlipixant: A New Hope for Refractory Chronic Cough?" | |||
| Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III) | 19 juin 2025 | 00:33:55 | |
This episode originally aired on March 23rd, 2023. Dr. Michael Lanspa chats with Dr. Yahya Shehabi about his article, "Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III)." | |||
| Early vs. Delayed Switching from Controlled to Assisted Ventilation: A Target Trial Emulation | 29 mai 2025 | 00:24:51 | |
Dr. Michael Lanspa chats with Dr. Carmen Reep and Dr. Leo Heunks about their article, "Early vs. Delayed Switching from Controlled to Assisted Ventilation: A Target Trial Emulation." | |||
| A New Global Definition of Acute Respiratory Distress Syndrome | 08 mai 2025 | 00:33:36 | |
This episode originally aired on January 17th, 2024. Dr. Michael Lanspa chats with Dr. Michael Matthay about his article, "A New Global Definition of Acute Respiratory Distress Syndrome." | |||
| Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease | 17 avr. 2025 | 00:46:19 | |
Dr. Mohleen Kang chats with Dr. Kerri Johannson and Dr. Tamera Corte about their article, "Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease." | |||
| Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline | 03 avr. 2025 | 00:16:39 | |
Dr. John Fleetham chats with Dr. Sonal Munsiff and Dr. Raquel Duarte about their article, "Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline." | |||
| Using Isoniazid More Safely and More Effectively in Tuberculosis Treatment | 20 mars 2025 | 00:35:16 | |
Dr. John Fleetham chats with Dr. Paolo Denti, Dr. Elisa Ignatius, Dr. Jason Andrews, and Dr. Neil Schluger about two papers and an editorial published in AJRCCM discussing the use of isoniazid in treating patients with tuberculosis. | |||
| A Randomized Controlled Trial Exploring Safety and Tolerability of Sulthiame in Sleep Apnea | 13 mars 2025 | 00:24:33 | |
Dr. John Fleetham chats with Dr. Hedner and Dr. Schmickl about their articles “A Randomized Controlled Trial Exploring Safety and Tolerability of Sulthiame in Sleep Apnea" and “Drug Therapy for Obstructive Sleep Apnea: Are We There Yet?” | |||
| Progressive Early Interstitial Lung Abnormalities in Persons At-Risk for Familial Pulmonary Fibrosis: A Prospective Cohort Study and Big Things Have Small Beginnings: Clinical Implications of Early Interstitial Lung Disease | 20 févr. 2025 | 00:27:14 | |
Dr. Mohleen Kang chats with Dr. Margaret Salisbury and Dr. Anna Podolanczuk about their articles, "Progressive Early Interstitial Lung Abnormalities in Persons at Risk for Familial Pulmonary Fibrosis: A Prospective Cohort Study" and "Big Things Have Small Beginnings: Clinical Implications of Early Interstitial Lung Disease." | |||
| Assessment of Home-based Monitoring in Adults with Chronic Lung Disease: An Official American Thoracic Society Research Statement | 13 févr. 2025 | 00:24:13 | |
Dr. John Fleetham chats with Dr. Yet Kor about her article, "Assessment of Home-based Monitoring in Adults with Chronic Lung Disease: An Official American Thoracic Society Research Statement." | |||
| Hypnotics on Obstructive Sleep Apnea Severity and Endotypes: A Systematic Review and Meta-Analysis and The Arousal Threshold: The ‘Weakest Link’ in OSA Pathogenesis? | 13 déc. 2024 | 00:37:57 | |
Dr. John Fleetham chats with Dr. Ludovico Messineo and Dr. Simon Joosten about their articles "Hypnotics on Obstructive Sleep Apnea Severity and Endotypes: A Systematic Review and Meta-Analysis" and "The Arousal Threshold: The ‘Weakest Link’ in OSA Pathogenesis." | |||
| Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine among Critically Ill Patients | 06 déc. 2024 | 00:33:45 | |
Dr. Michael Lanspa chats with Dr. Hannah Wunsch about her paper, "Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine among Critically Ill Patients." | |||
| From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU | 11 oct. 2024 | 00:27:47 | |
Dr. Michael Lanspa chats with Dr. Anthony Gordon about his article, "From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU." | |||
| Epidemiology and Prognostic Significance of Cough in Fibrotic Interstitial Lung Disease | 13 sept. 2024 | 00:21:32 | |
Dr. John Fleetham chats with Dr. Chris Ryerson and Dr. Yet Khor about their article, "Epidemiology and Prognostic Significance of Cough in Fibrotic Interstitial Lung Disease." | |||
| Senolytic-facilitated Reversal of End-Organ Dysfunction in a Murine Model of Obstructive Sleep Apnea | 05 juin 2024 | 00:32:44 | |
Dr. John Fleetham chats with Dr. Gozal on his article, "Senolytic-facilitated Reversal of End-Organ Dysfunction in a Murine Model of Obstructive Sleep Apnea." | |||
| Effectiveness of Fludrocortisone Plus Hydrocortisone Versus Hydrocortisone Alone in Septic Shock: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials | 28 mars 2024 | 00:20:49 | |
Dr. John Fleetham chats with Dr. Bijan Teja and Dr. Nicholas Bosch about their article, "Effectiveness of Fludrocortisone Plus Hydrocortisone Versus Hydrocortisone Alone in Septic Shock: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials." | |||
| Inhalable Textile Microplastic Fibers Impair Airway Epithelial Differentiation and Inhaled Microplastics and Airway Development: Concerning Evidence from Organoids | 21 févr. 2024 | 00:25:59 | |
Dr. John Fleetham chats with Dr. Barbro N Melgert and Dr. Chris Carlsten about their articles, "Inhalable Textile Microplastic Fibers Impair Airway Epithelial Differentiation" and "Inhaled Microplastics and Airway Development: Concerning Evidence from Organoids." | |||
| A New Global Definition of Acute Respiratory Distress Syndrome | 17 janv. 2024 | 00:33:05 | |
Dr. Michael Lanspa chats with Dr. Michael Matthay about his article, "A New Global Definition of Acute Respiratory Distress Syndrome." | |||
| External Control Arms in Idiopathic Pulmonary Fibrosis Using Clinical Trial and Real-World Data Sources and The Added Power of Synthetic Control Groups: Challenging Conventional Wisdom and Trial Design in Idiopathic Pulmonary Fibrosis Research | 16 janv. 2024 | 00:32:50 | |
Dr. Mohleen Kang chats with Dr. Aparna Swaminathan and Dr. Timothy Dempsey about their articles, "External Control Arms in Idiopathic Pulmonary Fibrosis Using Clinical Trial and Real-World Data Sources” and “The Added Power of Synthetic Control Groups: Challenging Conventional Wisdom and Trial Design in Idiopathic Pulmonary Fibrosis Research.” | |||
| The Combination of Aroxybutynin and Atomoxetine in the Treatment of Obstructive Sleep Apnea (MARIPOSA): A Randomized Controlled Trial and Pharmacologic Therapy for Obstructive Sleep Apnea: Are We Seeing Some Light at the End of the Tunnel? | 08 déc. 2023 | 00:22:43 | |
Dr. John Fleetham chats with Dr. Paula K. Schweitzer and Dr. Najib Ayas about their articles, "The Combination of Aroxybutynin and Atomoxetine in the Treatment of Obstructive Sleep Apnea (MARIPOSA): A Randomized Controlled Trial" and "Pharmacologic Therapy for Obstructive Sleep Apnea: Are We Seeing Some Light at the End of the Tunnel?" | |||
| FEV1/FVC Severity Stages for Chronic Obstructive Pulmonary Disease | 05 oct. 2023 | 00:16:21 | |
Dr. John Fleetham chats with Dr. Surya Bhatt about his article, “FEV1/FVC Severity Stages for Chronic Obstructive Pulmonary Disease.” | |||
| Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial | 28 sept. 2023 | 00:17:14 | |
Dr Michael Lanspa chats with Dr. Imeen van der Wal and Dr. Chloe Grim on their article, "Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial." | |||
| Pulse Wave Amplitude Drops Index: A Biomarker of Cardiovascular Risk in Obstructive Sleep Apnea | 20 juil. 2023 | 00:20:38 | |
Dr. John Fleetham chats with Dr. Raphael Heinzer about his article, "Pulse Wave Amplitude Drops Index: A Biomarker of Cardiovascular Risk in Obstructive Sleep Apnea." | |||
| Individualized Treatment Effects of Bougie vs Stylet for Tracheal Intubation in Critical Illness | 22 juin 2023 | 00:25:11 | |
Dr. Michael Lanspa chats with Dr. Kevin Seitz and Dr. Matthew Churpek about their article, "Individualized Treatment Effects of Bougie vs Stylet for Tracheal Intubation in Critical Illness." | |||
| Effectiveness of Bedaquiline Use Beyond Six Months in Patients with Multidrug-Resistant Tuberculosis | 11 mai 2023 | 00:22:12 | |
Dr. John Fleetham chats with Dr. Molly Franke and Dr. James Brust about their articles, "Effectiveness of Bedaquiline Use Beyond Six Months in Patients with Multidrug-Resistant Tuberculosis" and “Weighting” the evidence: How much bedaquiline is enough?" | |||
| Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III) | 23 mars 2023 | 00:33:22 | |
Dr. Michael Lanspa chats with Dr. Yahya Shehabi about his article, "Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III)." | |||
| Tuberculosis Diagnoses Following Wildfire Smoke Exposure in California | 02 mars 2023 | 00:17:50 | |
Dr. John Fleetham chats with Dr. Joseph Lewnard and Dr. Will Checkley about their articles, "Tuberculosis Diagnoses Following Wildfire Smoke Exposure in California" and "Tuberculosis, Wildfires, and Case-crossover Studies: An Epidemiological Trifecta." | |||
| Assessing Pretomanid for Tuberculosis (APT), a Randomized Phase 2 Trial of Pretomanid-containing Regimens for Drug-sensitive TB: 12-Week Results | 15 déc. 2022 | 00:15:01 | |
| Cardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness | 01 déc. 2022 | 00:24:05 | |
Papers discussed in today's episode: | |||
| High-Flow Versus VenturiMask Oxygen Therapy to Prevent Re-Intubation in Hypoxemic Patients After Extubation: A Multicenter, Randomized Clinical Trial | 24 nov. 2022 | 00:28:26 | |