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Explore every episode of the podcast MCAT Modules - Review
Dive into the complete episode list for MCAT Modules - Review. Each episode is cataloged with detailed descriptions, making it easy to find and explore specific topics. Keep track of all episodes from your favorite podcast and never miss a moment of insightful content.
| Title | Pub. Date | Duration | |
|---|---|---|---|
| 8:3. DNA Libraries and Generating cDNA | 15 août 2020 | 00:04:58 | |
Prot —> mRNA —> cDNA —> dsDNA. (Step 2 via reverse transcriptase and step 3 via DNA Polymerase). Now the dsDNA is injected into a virus which infects bacteria to make lots of the DNA.
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| 8:2. Polymerase Chain Reaction | 15 août 2020 | 00:06:57 | |
Denaturation (Heat to high temp), Primer Annealing (Cool slightly), Primer Extension via polymerase (Heat but not as much as step 1).
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| 8:1. Gel Electrophoresis | 15 août 2020 | 00:06:31 | |
GE find us the length of a DNA Strand (how many base pairs long).
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| 7:5. Applying the HP Equation | 10 août 2020 | 00:01:41 | |
Not really sure why I did a module on this - basically you know they’re homo recessive because they have blue eyes (the recessive trait), and you know to use q BECAUSE we’re dealing with the recessive trait.
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| 7:4. The Hardy-Weinberg Equation | 10 août 2020 | 00:02:40 | |
HP Equation gives P(allele frequencies). P^2 is probability of homo dominant, Q^2 is probability of homo recessive, 2pq is probability of heterozygous allele combo. P = frequency of dom allele, Q = frequency of recessive allele.
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| 7:3. Worked Example: Punnett Squares | 10 août 2020 | 00:06:05 | |
Discusses Dihybrid Crosses and the Law of Independent Assortment.
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| 7:2. Co-dominance and Incomplete Dominance | 10 août 2020 | 00:00:59 | |
Don’t let the title fool you. This is short. Discusses complete, incomplete, and co-dominance.
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| 7:1. An Introduction to Mendelian Genetics | 10 août 2020 | 00:06:47 | |
Discuss genes, alleles, geno/phenotypes, and punnet squares. The Khan Academy video discusses the history (Gregor Mendel) but let’s be real, who cares.
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| 6:5. The Effects of Mutations | 10 août 2020 | 00:02:14 | |
Mutations can be good, bad, or both.
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| 6:4. Mutagens and Carcinogens | 10 août 2020 | 00:08:19 | |
Define mutagens and then discuss endogenous and exogenous mutagens. (Endo: ROS); (Exo: intercalators, base analogues, carcinogens)
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| 6:3. The Causes of Genetic Mutations | 04 août 2020 | 00:10:46 | |
Small scale mutations (point: TTM; frame-shift: ID) and Large-scale mutations (translocation, inversion).
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| 6:2. The Different Types of Mutations | 04 août 2020 | 00:08:16 | |
Point, Frame Shift, and Nonsense vs. Missense. Further divided Missense to Silent, Conservative, and Non-Conservative.
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| 6:1. Introduction to Genetic Mutations | 03 août 2020 | 00:04:58 | |
Clarifies that mutations arise at the DNA level, and from where mutations originate.
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| 5:7. Tumor Suppressors | 03 août 2020 | 00:09:25 | |
Discusses categories of tumor suppressors and then 2 examples: pRb and p53, both proteins.
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| 5:6. Oncogenes | 03 août 2020 | 00:21:40 | |
Discusses the 3 mechanisms through which oncogenes are formed from proto-oncogenes, and types of oncogenes with examples.
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| 5:5. Non-Coding RNA | 26 juil. 2020 | 00:13:24 | |
I discuss ncRNAs (RNA that’s ready to perform tasks w/o becoming protein) and then move onto rRNA, tRNA, miRNA, snRNA, and snoRNA. Have fun with all these acronyms lol
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| 5:4. Post-Transcriptional Regulation | 20 juil. 2020 | 00:08:58 | |
Not really an important module but skip to 6:18 for new stuff (RNA Editing via the ADAR and CDAR Enzymes)
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| 5:3. Regulation of Transcription | 19 juil. 2020 | 00:17:27 | |
Discusses GTFs, then discusses activators/repressors and enhancers/silencers. Finally distinguishes between regulation of transcriptional euk and prok organisms.
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| 5:2. DNA and Chromatin Regulation | 18 juil. 2020 | 00:17:38 | |
Discusses HAT and HDAC enzymes to uncoil/coil DNA (uncoil = activate for transcription) then transitioned into DNA methylation as it relates to CpG Islands and MBB’s.
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| 5:1. The Lac Operon - Part 2 | 30 juin 2020 | 00:13:24 | |
More terminology of the Lac Operon mechanism, refined ideas from the first part.
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| 4:16. DNA Structure and Function (Random Info) | 30 juin 2020 | 00:08:15 | |
End of chapter random info (as I’ve done before). Although pay attention to end where I discuss donor:acceptor ratios of nucleobases.
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| 4:15. The Jacob Monod Lac Operon | 29 juin 2020 | 00:14:40 | |
Discusses why gene expression regulation occurs @ transcription level. Discusses the Jacob Monod Lac Operon’s structure (ZYA) and function (lactose metabolism) and how the repressor (@operator site) controls this process.
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| 4:14. Protein Modification | 27 juin 2020 | 00:30:51 | |
LISTEN @ 2x speed (on Apple podcasts). Discusses co- and post-translational modifications (GLUMPP) which occur for those proteins that aren’t fully ready to work even after translation finishes.
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| 4:13. Semi-Conservative Replication | 26 juin 2020 | 00:02:42 | |
Discusses the conservative (Incorrect), dispersive(Incorrect), and Semi-Conservative (Correct) theories of replication.
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| 4:12. DNA Repair 2 (response to Dimers) + Summary of BOTH DNA Repairs | 26 juin 2020 | 00:18:28 | |
Discuss endo- and exogenous factors that damage DNA, the process of Nucleotide Excision Repair (NER), and what happens when NER fails.
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| 4:11. DNA Repair 1 (response to Mutations) | 24 juin 2020 | 00:19:21 | |
(This is where the modules get longer/content heavy). Discusses exo- and endonucleases as well as the Mismatch Repair Mechanism as a physiological fail safe.
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| 4:10. Differences in translation between prokaryotes and eukaryotes | 22 juin 2020 | 00:09:59 | |
Strand structure, protection factors (proks have none), and starting A2 (proks = fmet // euks = met)
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| 4:9. Translation | 21 juin 2020 | 00:07:50 | |
Discusses the process using the APE Sites.
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| 4:8. Speed and Precision of DNA Replication | 21 juin 2020 | 00:00:44 | |
USELESS MODULE // I didn’t think I’d actually get it to 45 seconds LOL
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| 4:7. Transcription and mRNA Processing | 21 juin 2020 | 00:15:02 | |
I know we talked about this in 4:1 but this has more detail. Distinguishes between eukaryotic and prokaryotic transcription and reviews eukaryotic transcription in detail (with processing).
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| 4:6. The DNA Replication Process | 20 juin 2020 | 00:04:54 | |
(Yes it has a different name). The 8-step process.
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| 4:5. Telomeres and Single Copy DNA vs. Repetitive DNA | 19 juin 2020 | 00:11:35 | |
Introduce telomeres as “protective caps” to ensure protection and quality replication of DNA sequences. Also discuss single copy DNA (important for genetic info) vs repetitive DNA (telomeres are an example of this).
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| 4:4. Antiparallel Structure of DNA Strands | 19 juin 2020 | 00:03:39 | |
The strands (each of the 2 sugar phosphate backbones) run in opposite directions. That is all.
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| 4:3. Molecular Structure of DNA | 19 juin 2020 | 00:04:01 | |
Really just a recap of the previous module + the types of bonding that forms the Double Helix
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| 4:2. DNA (Overview) | 19 juin 2020 | 00:04:47 | |
Discuss DNA’s basic structure as well as the nitrogenous base pairs.
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| 4:1. Eukaryotic gene transcription (DNA —> RNA) | 16 juin 2020 | 00:18:28 | |
(Content heavy!) Transcription, Structural Differences of Nucleic Acids, mRNA Processing, and RNA Interference
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| 3:7. The Lineweaver-Burke Plot | 15 juin 2020 | 00:01:31 | |
Search up the Lineweaver-Burke Plot on your own.
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| 3:6. Covalent Modifications to Enzynes | 15 juin 2020 | 00:11:33 | |
Covalent Modifications are changes made to a protein to accomplish a variety of tasks (activate, deactivate, etc). I discuss Small Post-translational Modifications, Zymogens, and Suicide Inhibitors.
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| 3:5. Non-enzymatic Protein Function | 15 juin 2020 | 00:11:19 | |
MARTI (Motor, Antibodies, Receptors, Transport, and Ion Channel) Proteins. Don’t forget LITHOL for types of enzymes.
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| 3:4. Allosteric Regulation and Feedback Loops | 14 juin 2020 | 00:15:22 | |
Discuss allostery, feedback loops, and the phosphofructokinase enzyme and it how it is involved in a feedback loop. (Pretty long module)
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| 3:3. Cooperativity (or Cooperative Binding) | 11 juin 2020 | 00:08:04 | |
Details positive, negative, and noncooperation binding.
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| 3:2. Steady States and the Michaelis-Mentin Equation | 11 juin 2020 | 00:12:04 | |
Discusses the steady state assumption and its equation, the MM Equation, and the catalytic efficiency equation. Also notes Kcat and Km and their interpretations.
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| 3:1. An Introduction to Enzymes Kinetics | 11 juin 2020 | 00:10:27 | |
I discuss the 3 assumptions that allow for the (many) conclusions we will reach later in this season.
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| 2:7. Enzymes and their Local Environment | 11 juin 2020 | 00:05:05 | |
The effects of the pH and Temperature factors on catalysis.
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| 2:6. Cofactors, Coenzymes, and Vitamins | 11 juin 2020 | 00:05:55 | |
What they are and some examples. Discuss his minerals as well.
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| 2:5. Six Types of Enzymes | 11 juin 2020 | 00:11:52 | |
LITHOL // Transferase, ligase, oxidoreductase, isomerase, hydroplane, lyase
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| 2:4. Induced Fit Model of Enzyme Catalysis | 09 juin 2020 | 00:07:59 | |
Details active and allosteric site binding and distinguishes between reaction and regulation.
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| 2:3. Enzymes and Activation Energy | 09 juin 2020 | 00:04:59 | |
Details how catalysts affect a reaction.
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| 2:2. Intro to Enzymes and Catalysts | 08 juin 2020 | 00:04:52 | |
It’s in the title.
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| 2:1. Enzyme Structure and Function | 08 juin 2020 | 00:01:47 | |
Discusses catalytic conditions and collision theory.
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