Explore every episode of the podcast Matters Microbial

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	Title	Pub. Date	Duration
	Matters Microbial #139: How Listeria Gets By With a Little Help From Its Friends	23 Sep 2026	01:00:56
Matters Microbial #139: How Listeria Gets By With a Little Help From Its Friends September 23, 2026 Today Dr. Jasna Kovac, Huck Chair in Microbiomes in Food Safety and Associate Professor of Food Science at Penn State University (and active member of Penn State's One Health Microbiome Center) *joins the quality quorum to discuss how understanding the microbiome in food processing facilities can help reduce the incidence of food borne illnesses, including Listeria.* Host: Mark O. Martin Guest: Jasna Kovac Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is an overview of Listeria as a microbe. Here is an overview of Listeria pathogenesis. A video showing "actin rockets" moving Listeria around inside of a eukaryotic cell. Overview from the CDC regarding Listeria. Prior #MattersMicrobial podcast about Listeria by Dr. Lisa Gorski. An overview of microbial food safety issues. Description of the cantaloupe associated Listeria outbreak. Description of the caramel apple Listeria outbreak. An overview of whole genome sequencing as a diagnostic tool. A video description of MIC (minimal inhibitory concentration) relationship between microbes and antimicrobials. An overview of biofilms. A prior #MattersMicrobial podcast about biofilms with Dr. Matthew Fields. The One Health Concept linking many aspects of everyday life to microbiology. A description of Sanger 16S rRNA sequencing. An overview of MPN (most probably number) analysis in microbiology. A video describing the very useful LIVE/DEAD dye approach in microbiology. Microbiology and sanitizers. An overview of EPS (extracellular polysaccharides). Description of SNPs (single nucleotide polymorphisms). An overview of the lineages of Listeria. A description of Dr. Kovac's approach to precision food safety. A nice description of Dr. Kovac's evaluation of tree fruit processing plants described in this podcast. A wonderful video presentation by Dr. Kovac. Dr. Kovac's academic website. The research laboratory website for Dr. Kovac and colleagues. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #138: Sightseeing the Microbial World	08 Sep 2026	00:56:34
Matters Microbial #138: Sightseeing the Microbial World September 8, 2026 Today Dr. Monika Oli, Instructional Professor of the Department of Microbiology and Cell Science at the University of Florida joins the quality quorum to discuss how she teaches microbiology students to view the topic through a global lens as a study abroad program. Her approach demonstrates how travel enriches scientific understanding, broadens cultural perspectives, and prepares students to become globally engaged microbiologists equipped to address the challenges of an interconnected world. Host: Mark O. Martin Guest: Monika Oli Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to some basic history of microbiology. A nice biography of Antonie van Leeuwenhoek. A truly wonderful video about Leeuwenhoek that is SO worth your time. A description of the "Leeuwenhoek Microscope." A website that explains how you can build a replica of this famous instrument. An overview of the Delft school of microbiology. A biography of Martinus Beijerinck (an amazing microbiologist). The website of Micropia, the microbiology focused museum in Amsterdam. A fun article about the "tardigrade chair" at Micropia I discussed. An article about "microbial tours." The CEPA company that helps to create academic tours. An overview of experiential learning. The story of Ignaz Semmelweis. A description of the abbey where Gregor Mendel did his work with pea plants. A biography of Karl Stetter. An amazing video featuring Karl Stetter. The famous book, "The Little Prince," by Antoine de Saint-Exupéry which can be linked to microbiology. How some UNESCO Heritage sites are related to microbiology. The fermented food kimchi and its microbiological origin. The microbiology of sourdough bread. A video by Dr. Oli describing the ideas behind her microbial tours. A microbiology themed tour program by BYU. An ASM biography of Dr. Oli. The faculty website of Dr. Oli. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #137: The Living Skin of Our Planet	25 Aug 2026	01:07:29
Matters Microbial #137: The Living Skin of Our Planet August 25, 2026 Today Dr. Estelle Couradeau, Assistant Professor in the Department of Ecosystem Science and Management and the Huck Institutes of the Life Sciences at the Pennsylvania State University, joins the quality quorum today to discuss the role that the soil microbiome can play in terms of agriculture, moderating temperature, and protecting specific environments. Host: Mark O. Martin Guest: Estelle Couradeau Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The Erskine Foundation fellowship website. An overview of Paenibacillus. An article discussing the fascinating colonial morphology often found with Paenbacillus. A blog post that demonstrates that the odd appearance of Paenibacillus can be used by other microbes for dispersal! Dr. Jo Handelsman's essential book, "A World Without Soil." A fine video describing the soil microbiome. The complexity of soil with regard to where and how microbes can live. Science journalist Carl Zimmer's indispensable essay likening the microbial ecology of lakes to the human body: "The Human Lake." An overview of dormancy in microbes. The "BonCat" (bio-orthogonal non-canonical amino acid tagging) technique for detecting living microbes in a sample without cultivation. An overview of flow cytometry in microbiology. An essay suggesting that marine bacteria are involved in the production of clouds. An article about climate change and microbes. An article about cyanobacteria and "sunscreen." A review article about the "biocrust" concept. A video overview of beautiful and fascinating microbial fossils: stromatolites. A video by Dr. Couradeau describing her research. Articles by Dr. Couradeau and colleagues asking which microbes are active in soil: here, here, and here. Articles by Dr. Couradeau and colleagues asking if microbes can change the temperature of a desert: here and here. Articles by Dr. Couradeau and colleagues that explore the hidden microbiomes of Andean páramo wetlands: here and here. Dr. Couradeau's faculty website. Dr. Couradeau's research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #136: When Bacteria Open the Wrong Door	11 Aug 2026	01:06:01
Matters Microbial #136: When Bacteria Open the Wrong Door August 11, 2026 Today Dr. Michael D.L. Johnson, Associate Professor of Immunobiology at the University of Arizona, joins the quality quorum today to discuss copper, microbiology, and a possible new strategy to fight bacteria that cause disease. Host: Mark O. Martin Guest: Michael D. L. Johnson Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A link to Hartiful, the Etsy artist who custom creates glow in the dark (and many other kinds) pins. A link to the essential science artist Beatrice the Biologist. A link to World Microbiome Day. A link to Micropia, the microbiology museum in Amsterdam. A recent article on the growing threat of antibiotic resistance among disease causing bacteria. A video demonstrating the Kirby Bauer procedure, which shows antimicrobial effects and zones of inhibition. A link to an earlier #MattersMicrobial episode with Dr. Michael Schmidt describing copper and microbes. A review article describing the impact that copper can have on microbes. A review article on Streptococcus pneumoniae, the organism with which Dr. Johnson works. An video celebrating the role that S. pneumoniae had in determining that DNA was the genetic material prior to World War 2. An overview of siderophores that help microbes obtain needed iron. An article about redox activity and copper and microbes. The relationship between metal toxicity and antimicrobial activity. The role that copper plays in agriculture. The differences between Gram positive and Gram negative bacteria. An article on efflux pumps and metal toxicity in microbes. An article describing how iron binding proteins also bind copper. An article describing how zinc interacts with microbes. A wonderful description of Dr. Johnson's "Trojan Horse" approach to battle disease causing microbes. A relevant review article by Dr. Johnson and his colleagues discussing copper and microbes. An overview of the "Hypothesis Fund," which supports unusual ideas in science. A video of Dr. Johnson describing his research. Dr. Johnson's faculty website. Dr. Johnson's research laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #135: Biofilms in Motion—The Adorable Zorbs	30 Jul 2026	01:01:35
Matters Microbial #135: Biofilms in Motion—The Adorable Zorbs July 30, 2026 Host: Mark O. Martin Guest: Jo Handelsmann, Shruthi Magesh Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to the Etsy shop where one can buy the wonderful "THIS IS WHAT A MICROBIOLOGIST LOOKS LIKE" enamel pins. Here is a link to the World Microbiome Day website. Here is a link to the interesting work of Contamination Club. The story of Alexander Fleming's famous contaminant that led to the discovery of penicillin. Here is a link to Dr. Handelsman's recent book, "*A World Without Soil." Highly recommended. The website for Dr. Handelsman's wonderful "Tiny Earth" program, helping students worldwide to screen soil for antimicrobial production (and learning about microbial diversity). An overview of the microbial complexity of soil. A video overview of biofilms. A video overview of types of bacterial motility. A video overview of "gliding motility" among bacteria. Some bacteria can "hitchhike" or are carried by other bacteria, such as Paenibacillus. Learning about an odd sport involving "zorbs." An introductory essay on "zorbing" and motility. Another introductory essay on "co-zorbing," the topic of today's discussion. A description of Flavobacterium johnsoniae, which carries out "zorbing." The original article on THOR ("The Hitchhikers of the Rhizosphere*") by Dr. Handelsman and colleagues. The original "zorb" paper by Dr. Handelsman and colleagues that was discussed during today's podcast. The "co-zorb" paper by Dr. Handelsman, Dr. Magesh, and colleagues that was discussed during today's podcast. A fascinating video by Dr. Handelsman and her path to becoming a microbial scientist. Highly recommended.. Dr. Handelsman's faculty website. The website for the Wisconsin Institute for Discovery. Dr. Handelsman's research laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #134: Could Alien Life Use Different Chemistry?	14 Jul 2026	01:01:55
Matters Microbial #134: Could Alien Life Use Different Chemistry? July 14, 2026 Today Dr. Morgan Sobol, Assistant Professor in the Department of Biology at Texas State University, joins the Quality Quorum today to discuss how microbes on early earth began interacting with elements like nitrogen, making life possible here and perhaps elsewhere in the universe! You will learn about the fundamental and amazing enzyme nitrogenase! Host: Mark O. Martin Guest: Morgan Sobol Download MM134 (37 MB MP3, 62 mins) Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The website for ASM Microbe, the annual meeting of microbiologists. The "live" #MattersMicrobial session recorded at ASM Microbe, with Dr. Hannah Reich. An essential article about "A World Without Microbes." A video version of "A World Without Microbes." An introduction to microbial ecology. An overview of the enzyme that fixes carbon dioxide into organic matter, Rubisco. An overview of the enzyme that converts practically inert dinitrogen gas into bioavailable ammonia, nitrogenase. A short essay on metalloenzymes, including nitrogenase. An overview of nitrogen fixing microbes, and the strategies they use. A review editorial describing the burgeoning field of astrobiology. A link to a NASA program exploring early evolution of microbial life. An article on the microbially caused Great Oxidation Event that changed our atmosphere eons ago, making life like forms like ours possible. An article exploring the evolution of microbial nitrogen fixation. An abstract by Dr. Sobol and colleagues, discussing the evolution of nitrogen fixation in an ancient ecological context. A lovely article about the microbiology of Yellowstone National Park. Dr. Sobol's faculty website. Dr. Sobol's interesting research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #133: The Microbial Partnerships That Help Corals Survive	30 Jun 2026	00:31:25
Matters Microbial #133: The Microbial Partnerships That Help Corals Survive June 29, 2026 Dr. Hannah Reich of the Department of Environmental Biology at the State University of New York's College of Environmental Science and Forestry joins the #QualityQuorum to discuss how microalgal interactions (including with bacteria) are fundamental contributors to large scale ecosystem processes including the ocean carbon pump, the duration of algal blooms, and the evolutionary success of coral reefs. Host: Mark O. Martin Guest: Hannah Reich Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An essay on the coral holobiont. A discussion of the phycosphere. A discussion of the rhizosphere. A review of the roles of iron in microbial biology. An overview of siderophores in the microbial world. An article about iron, the warming oceans, and coral. A VERY recent article by Dr. Reich and colleagues regarding siderophores in the coral holobiont. A very nice short video by Dr. Reich explaining her work at ESF. Dr. Reich's faculty website. Dr. Reich's fascinating laboratory group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #132: What 83,000 Generations of Bacteria Reveal About Evolution	17 Jun 2026	01:05:01
Matters Microbial #132: What 83,000 Generations of Bacteria Reveal About Evolution June 17, 2026 Today Dr. Jeffrey Barrick, John A. Hannah Distinguished Professor of the Department of Microbiology, Genetics, & Immunology and the Department of Entomology at Michigan State University, joins the quality quorum today to discuss how microbes can be used to study evolution itself. He will also discuss the impressive and ongoing LTEE program, the experiments that originate from it, and what they tell us about evolution. Host: Mark O. Martin Guest: Jeffrey Barrick Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to an article about the late great Abigail Salyers. Here is what I wrote about Dr. Salyers. I learned so much from her. An article about the contributions of Dr. Theodosius Dobzhansky to the study of evolution. The concept of contingency during evolution. An overview of microbial evolution. A link to "Microbes and Evolution," a book discussed during this podcast. A link to "A Primer for Experimental Evolution," a book discussed during this podcast. The concept of Growth Advantage in Stationary Phase (GASP). A video about the MEGA plate experiment by Dr. Michael Baym and colleagues. This is a "must watch." An video about Dr. Richard Lenski, originator of the LTEE. Dr. Lenski's website. The LTEE (long term evolutionary experiment) website. There is so much here to explore. An excellent introduction to the LTEE. An article about the amazing " climbing citrate mountain" innovation during LTEE described in the podcast. A video by Dr. Lenski about LTEE. A video by Dr. Barrick that is worth your time. Dr. Barrick's faculty website at Michigan State University. Dr. Barrick's research laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #131: What Cystic Fibrosis Reveals About Hidden Microbial Lives	03 Jun 2026	01:02:40
Matters Microbial #131: What Cystic Fibrosis Reveals About Hidden Microbial Lives June 3, 2026 Today Dr. Sam Brown, Professor of Biological Sciences at Georgia Tech University, joins the quality quorum today to discuss the social lives of bacterial pathogens. He will also discuss VERY recent research from his lab group exploring the specialist/generalist problem in Pseudomonas aeruginosa, and thoughts on cryptic convergent specialization! Host: Mark O. Martin Guest: Sam Brown Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of behavioral ecology. An article describing evolutionary trade offs and game theory. A video describing Tinbergen's "Four Whys" involving behavioral ecology. A wonderful essay by Carl Zimmer relating lake ecology and microbial ecology in humans. A Pseudomonas plush toy from Giant Microbes. The Pseudomonas contaminated eyedrops story told by Dr. Brown, as summarized by the CDC. An essay about sociomicrobiology. An overview of quorum sensing. An overview of biofilms. An article describing specialization versus generalism in ecology. A description of a "confusion matrix" in data analysis. A somewhat dated overview of PCA (principle component analysis). The article about convergent cryptic specialization under discussion today on this podcast from Dr. Brown's research group (first author Mehlferber). A VERY interesting article from Dr. Brown's research team describing eco-evolutionary aspects of polymicrobial infections. Dr. Brown's faculty website. Dr. Brown's laboratory group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #130: The Holobiont — Animals, Microbes, and Ecology	25 May 2026	01:03:25
Matters Microbial #130: The Holobiont — Animals, Microbes, and Ecology May 19, 2026 Today Dr. Kevin Kohl, Associate Professor of Biological Sciences at the University of Pittsburgh, joins the #QualityQuorum to discuss how he and his colleagues study the interplay between animals, their resident gut microbes, and the overarching concept of the holobiont. Host: Mark O. Martin Guest: Kevin Kohl Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The One Health Microbiome Center at Pennsylvania State University. A very fine essay on the holobiont concept for non-microbiologists. A general introductory overview of the holobiont concept. The holobiont concept and the coral symbiosis. A partial history of the development of the holobiont concept. Dr. Casadevall suggests that context and thus outcomes describes the term "pathogen," and a similar analysis applies to the holobiont. A very short description of the holobiont concept. Another overview of the holobiont concept in general, coauthored by Dr. Kohl. Some basic rules for thinking about the holobiont concept. A video introduction to the holobiont concept, by Dr. Seth Bordenstein. I highly recommend this essay by the science writer Carl Zimmer, "The Human Lake," to think of the connections between lake ecology and microbial interactions with humans. Another wonderful article recommended by Dr. Kohl, by Dr. Margaret McFall-Ngai and coauthors, detailing the impact microbes have on animals over evolution and development. The wood rat – creosote – microbiome connection to the holobiont concept, discussed on this podcast (coauthored by Dr. Kohl). The fascinating work by Dr. Kohl and colleagues showing the relationship between tadpole development and pond microbes discussed in this podcast. A must read article by Dr. Kohl and colleagues, "Through the microbial looking glass: our shifting understanding of the holobiont and microbes as mediators of organismal biology," illustrates the development and influence of the holobiont concept. Dr. Richard Prum's book, "Performance All the Way Down," was discussed during this podcast. There is also a video where Dr. Prum discusses the ideas in this book, describing gene regulation as a performance. Dr. Kohl's faculty website. Dr. Kohl's (very interesting) research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #129: Microbes Reveal How Evolution Might Replay	05 May 2026	01:07:54
Matters Microbial #129: Microbes Reveal How Evolution Might Replay May 5, 2026 Today Dr. Michael Travisano, Distinguished McKnight University Professor in the College of Biological Sciences of the University of Minnesota, joins the #QualityQuorum to discuss fascinating work from his lab group exploring evolutionary questions from a microbial perspective. Host: Mark O. Martin Guest: Michael Travisano Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is the link to the article we discussed during the podcast, authored by Dr. Travisano and Dr. Rainey. An overview of the concept of adaptive radiation. The ecological/evolutionary concept of "cheating" which applies to the mat forming bacteria discussed in this podcast. A link to an article by Dr. Jo Handelsman and colleagues about THOR, a simple microbial community that has shows great functional diversity. A wonderful essay about Dr. Rich Lenski's role in the LTEE. An essay from "Small Things Considered" describing "rewinding" evolution using microbial systems. A wonderful book by Stephen Jay Gould, "Wonderful Life" about evolution. Another book well worth your attention: "Chance and Necessity" by Jacques Monod. An article about the challenges of multicellularity in bacteria. The wonderful short video example of "snowflake yeast" evolving within days. A link to another #MattersMicrobial podcast by Dr Will Ratcliff, about "snowflake yeast." An article by Dr. Travisano and colleagues describing conflict and cooperation in microbial societies discussed on this podcast. An article by Dr. Travisano and colleagues about the evolution of "snowflake yeast," discussed on this podcast. An article by Dr. Travisano and colleagues discussing the role of other microbes in the development of multicellularity, discussed on this podcast. An article by Dr. Travisano and colleagues, on the repeatability of microbial adaptive evolution discussed on this podcast. A list of references authored by Dr. Travisano and colleagues. Dr. Travisano's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #128: C. diff from Nursery to Nursing Home	21 Apr 2026	01:04:43
Matters Microbial #128: C. diff from Nursery to Nursing Home April 20, 2026 Today Dr. Joseph Zackular, Assistant Professor of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania, joins the #QualityQuorum to discuss some fascinating microbiology involving the bacterium Clostridiodes difficile (also known as C. diff), which can cause disease in infants, the elderly, and the immunocompromised. Host: Mark O. Martin Guest: Joseph Zackular Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An essay about siderophores in bacteria. The Giant Microbes "Cdiff" toy. The website of Dr. Patrick Schloss. A link to the #MattersMicrobial podcast with Dr. Schloss. An overview of Clostridioides difficile from a patient / physician perspective. A review article of research involving Clostridioides difficile. An overview on polymicrobial diseases. A wonderful opinion piece by Dr. Arturo Casadevall regarding the term "pathogen." An overview of Enterococcus in the gut microbiome. The technology of imaging mass spectrometry. An article on Stickland fermentation of amino acids among gut bacteria. Work by Dr. Zackular and colleagues discussed in this podcast, describing how FMT can be used as a treatment. Work by Dr. Zackular and colleagues discussed in this podcast, describing how different members of the host microbiome interact, and how that relates to disease. Work by Dr. Zackular and colleagues discussed in this podcast, describing the role of amino acid metabolism to changes in microbiome structure. Work by Dr. Zackular and colleagues discussed in this podcast, describing how Enterococcus can modulate the disease causing characteristics of C. difficile. An interesting paper showing that polymicrobial effects are more common than expected. An article arguing that there is no single "healthy" microbiome. A lovely primer on this topic for most nonmicrobiologists. An overview on fecal microbiome transplants and the treatment of human disease. The website for the Center for Microbial Medicine at the University of Pennsylvania. A great video by Dr. Zackular and colleagues, well worth your time. Dr. Zackular's academic website. Dr. Zackular's laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #127: Even Your Navel Has Them — An Archaea‑Whisperer Explores	07 Apr 2026	01:09:42
Matters Microbial #127: Even Your Navel Has Them — An Archaea‑Whisperer Explores April 7, 2026 Today Dr. Nahui Medina-Chavez, postdoctoral scholar in the Travisano laboratory at the University of Minnesota, joins the Quality Quorum to discuss her interest in the ubiquitous archaea, and her own research studying experimental evolution in extreme halophiles. Host: Mark O. Martin Guest: Nahui Medina-Chavez Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is an article on R2A, which is used to cultivate water associated microbes. A solid and clear article describing the "great uncultivated majority." An article describing the discovery of the archaea. An engaging video summary of the archaea. A recent article suggesting that archaea are the root and originator of eukaryotes like ourselves! An interesting video about the lokiarcheota, which contain the genetic echoes of eukaryotic life. An article about the extremely halophilic archaea. Do extreme halophiles live within salt crystals? The beautiful pink pigment, bacteriorhodopsin, associated with these archaea (despite the "bacterio" portion of the name). The LTEE experiment, describing how researchers can study evolution in the laboratory. Genomic islands in microbiology. The "Archaeal Power Hour" website. A fine video presentation by Dr. Medina-Chavez on archaea. A fine article by Dr. Medina-Chavez and her postdoctoral advisor Dr. Michael Travisano on archaeal communities. Dr. Medina-Chavez's Research Gate website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #126: Squid Eggs Come With Antifungal Frosting	24 Mar 2026	01:01:09
Matters Microbial #126: Squid Eggs Come With Antifungal Frosting March 24, 2026 Today Dr. Spencer Nyholm, Professor in the Department of Molecular and Cell Biology at the University of Connecticut, and Director of the Professional Science Master's Program in Microbial Systems Analysis, joins the Quality Quorum to discuss his research group's work exploring how some squid have harnessed microbes to protect their eggs against pathogens! Host: Mark O. Martin Guest: Spencer Nyholm Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is an overview of coral reef symbioses. The website for the famed Microbial Diversity course at the Marine Biological Laboratory at Woods Hole—a superb and life changing experience for any microbial scientist. An extremely fun video by Ed Yong (featuring Dr. Ned Ruby and Dr. Margaret McFall-Ngai) about the Euprymna scolopes – Vibrio fischeri symbiosis. Prior #MattersMicrobial podcasts related to Euprymna scolopes symbioses from Dr. Ruth Isenberg, Dr. Mark Mandel, and Dr. Margaret McFall-Ngai. The website for Dr. Ruby and Dr. McFall-Ngai which is so very worth your time. An overview of the power of confocal laser microscopy. The Clasi-FISH technique developed by Dr. Jessica Mark Welch (who also was on this podcast, here). The mass spectrometry approach to learning about small bioactive molecules, used by Dr. Marcy Balunas (who also was on this podcast, here). The concept of lightsheet microscopy. Dr. Nyholm discussed his article during the podcast, an overall review of the squid-Vibrio symbiosis. Dr. Nyholm discussed this article during the podcast, from his research team, describing how accessory nidemental gland microbes can protect squid eggs from fungal attack. Dr. Nyholm discussed this article during the podcast, from his research team, describing the development of the accessory nidemental gland and its microbiota. Dr. Nyholm discussed this article during the podcast, describing early work from his research team (including a former undergraduate student of mine!), exploring the microbes associated with the ANG. Concerns about fungal disease and global climate change, described by Dr. Arturo Casadevall (who was on this podcast, here). Searching for BGCs (biosynthetic gene clusters) in hopes of finding antimicrobial compounds. A link to Dr. Nyholm's faculty webpage. A link to Dr. Nyholm's laboratory group webpage. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #125: Antibiotics, Streptomyces and Evolution	15 Mar 2026	01:10:24
Matters Microbial #125: Antibiotics, Streptomyces and Evolution March 15, 2026 Today Professor Paul Hoskisson, Royal Academy of Engineering Research Chair in Engineering Biology at the University of Strathclyde joins the Quality Quorum to discuss his research group's adventures studying how the bacterium Streptomyces develops, produces antibiotics, and evolves! Host: Mark O. Martin Guest: Paul Hoskisson Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a biographical sketch of the impact of Carl Woese on microbiology. Here is a fine (if dated) video describing Woese's impact and work. It's truly wonderful to hear Woese himself discuss his work and challenges. Yours truly wrote an essay on Carl Woese and undergraduate education. An article on geosmin and actinobacteria. It may smell like soil, but it has other functions, like attracting springtails! An overview of the genus Streptomyces. A video showing the beauty of the life cycle of Streptomyces and various interactions. Linear genomes in bacteria. An overview of antibiotics. Selman Waksman and early antibiotics. And a Nobel Prize! The remarkable Julian Davies and antibiotic function. Davies' concept of small molecules with functions: the parvome. A wonderful collection of articles in honor of Julian Davies. The antibiotic resistance crisis that we all face. Rapamycin and the organism that synthesizes that compound, which is an immunosuppressant helpful in organ transplantation. The concept of Biosynthetic Gene Clusters (BGC). Rich Lenski and the LTEE program to study evolution in bacteria. A wonderful video of Dr. Lenski discussing that program. The use of "evolution in the lab" with bacteria to develop new functions and activities. Possibility of "evolution proof" antibiotics. Work discussed during this podcast from Dr. Hoskisson's laboratory group exploring experimental evolution in Streptomyces. Work discussed during this podcast from Dr. Hoskisson's laboratory group investigating the evolution of natural product synthesis. Work discussed during this podcast from Dr. Hoskisson's laboratory group investigating the known and unknown genes involved with secondary metabolite production. Dr. Hoskisson's laboratory group website. Dr. Hoskisson's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #124: How Bacteria Die in the Microbial Marine Forest	24 Feb 2026	01:01:55
Matters Microbial #124: How Bacteria Die in the Microbial Marine Forest February 24, 2026 Today Dr. Anne Thompson, Research Assistant Professor in the Department of Biology at Portland State University, joins the #QualityQuorum to discuss the small but necessary microbes in our oceans. They are hugely abundant, use strategies that produce the very oxygen we breathe, and live within an unseen marine jungle! Host: Mark O. Martin Guest: Anne Thompson Download MM124 (37 MB MP3, 62 mins) Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a wonderful essay about the marine cyanobacterium Prochlorococcus, probably the most abundant photosynthetic organism on Earth. Here is a wonderful presentation about the marine bacterium Pelagibacter, likely the most abundant organism on the planet. Here is a wonderful TED talk by the inspirational Dr. Penny Chisolm of MIT about the wonders of Prochlorococcus. PLEASE watch this wonderful video by a wonderful and inspiring scientist. A description of the Great Oxidation Event, caused by early cyanobacteria, which changed our planet. A lovely and fascinating essay about microbial numbers in the ocean and other ecosystems. A video overview of flow cytometry, which was essential to understanding the very small microbes in the ocean. A Scientific American article about the "Invisible Forest" of marine microbes, by Falkowski. A video overview of the picocyanobacteria, including Synechococcus and previously discussed Prochlorococcus. The essential work of Dr. John Waterbury of the Woods Hole Oceanographic Institute and photosynthetic marine microbes. An overview of the predators of the marine picocyanobacteria by Dr. Thompson and collaborators. The work of Dr. Kelly Sutherland of the University of Oregon, who collaborates with Dr. Thompson. A video describing the wonderfully strange choanoflagellates, which may resemble the first multicellular organisms on our planet, discussed on the podcast. The "mucus nets" of the organisms that Dr. Thompson and collaborators study, which may prey upon picocyanobacteria. A very clear overview of the research interests of Dr. Thompson and her coworkers. A nice video by Dr. Thompson about her research. Dr. Thompson's faculty website at Portland State University. Dr. Thompson's wonderful laboratory website. The website for an upcoming book that Dr. Thompson is preparing on the microbial marine forest and its importance to life on Earth. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #123: What Whooping Cough Can Teach US	06 Feb 2026	01:07:32
Matters Microbial #123: What Whooping Cough Can Teach Us February 6, 2026 Today Dr. Seema Mattoo, Associate Professor of Biological Sciences at Purdue University, joins the #QualityQuorum to discuss the fascinating molecular genetics of the bacterium Bordetella pertussis, which can cause the human disease whooping cough. Host: Mark O. Martin Guest: Seema Mattoo Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to Tiffany Ard's fine science related art. CDC information regarding Whooping Cough also called pertussis. An overview of the causative agent of whooping cough, Bordetella pertussis. A video about pertussis and its symptoms and treatment. More detail about B. pertussis and close relatives. Recent outbreaks of pertussis. An overview of vaccine development and its history for B. pertussis. An article about vaccine hesitancy and the return of childhood diseases like pertussis. Information on "whole cell" versus "acellular" vaccines. An article discussed today, demonstrating that the same molecule (a fragment of bacterial cell wall peptidoglycan) can be a factor for disease in humans, and facilitate symbiotic light organ development in the Hawai'ian Bobtail Squid More information of B. pertussis' trachael cytotoxin, or TCT. An overview of bacterial effectors interacting with our physiology in general. The concept of virulence factors. IgA versus IgG responses to infections. An overview of Type III Secretion Systems. An overview of sigma factors in bacteria. ECFs as sigma factors. Partner-switching studies. Fic genes. An overview of post translational modification. An essay on Theodosius Dobzhansky and his famous maxim. Protein misfolding and disease. The role of mentorship in science. The Hypothesis Fund and its aims. An article by Dr. Mattoo and colleagues discussed today about partner switching and Type III Secretion Systems. An article by Dr. Mattoo and colleagues discussed today about Fic proteins and adenylation. An article by Dr. Mattoo and colleagues discussed today about Fic proteins, post translational modification, and Parkinson's Disease. An article by Dr. Mattoo and colleagues discussed today about AMPylation, Fic proteins, and sensing misfolding in the endoplasmic reticulum. Dr. Mattoo's faculty website. The fascinating laboratory website of Dr. Mattoo and colleagues. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #122: Jumbo Marine Viruses and Nanoscopic Warfare	26 Jan 2026	01:05:36
Matters Microbial #122: Jumbo Marine Viruses and Nanoscopic Warfare January 26, 2026 Today Dr. Alaina Weinheimer, Simons Foundation Postdoctoral Fellow in Marine Microbial Ecology at the Bigelow Laboratory for Ocean Sciences, joins the #QualityQuorum to discuss new and intriguing marine viruses, including Jumbo Phages! Host: Mark O. Martin Guest: Alaina Weinheimer Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video overview of the wonderful world of bacterial viruses, or bacteriophages. A review article describing the roles that bacterial viruses can play in ecology. A description of changes in viral taxonomy, leading to the "realms" concept. An overview of "jumbo phages." Dr. Weinheimer's concept of "wumbology" from the cartoon "Spongebob Squarepants." An article describing host defenses found within bacteriophage genomes. An article by Dr. Weinheimer and colleagues describing lysogeny as a "plastic trait," and the possibility that all bacterial viruses can integrate into host genomes. The Bigelow Laboratory for Ocean Sciences website. The Bigelow Laboratory multimedia site. The webpage for the "Single Cell Genomics Center" at the Bigelow Laboratory. An article by Dr. Weinheimer and colleagues on exploring marine "jumbo phages." Marine "jumbo phages" blogpost for novice micronauts. An article about finding uridine within viral DNA genomes. Dr. Weinheimer's five minute talk about her research—highly recommended. The "Oceans on Tap" Facebook page describing marine biological research at the Bigelow Laboratory.. The Simons Foundation website (which has sadly eliminated the postdoctoral fellowship awarded to Dr. Weinheimer for her work). Dr. Weinheimer's personal website, including background and research interests. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #121: Phollowing Phage in the Gut Microbiome	08 Jan 2026	00:57:58
Matters Microbial #121: Phollowing Phage in the Gut Microbiome January 7, 2026 Today Dr. Liz de Ora Ortiz, postdoctoral scholar in the Secor Laboratory at Montana State University, joins the #QualityQuorum to discuss a fascinating new technology that allows investigators to follow bacteriophage infections in live animals. Host: Mark O. Martin Guest: Liz de Ora Ortiz Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The fascinating and frustrating (for researchers like me) story of Vampirococcus. A Vampirococcus summary for new #Micronauts. An overview of Agrobacterium, a bacterium about which all micronauts should know (think about genetic engineering in agriculture!). The story of Pelagibacter, very probably the most abundant organism on Earth. The story of Akkermansia, and its impact on metabolic health and the gut microbiome. An important essay by the late Dr. Elio Schaechter regarding paradigm shifts in microbiology. Much recommended! A truly wonderful video about bacteriophages and their importance. A simple video explaining the life cycle of lytic and lysogenic bacteriophages. A video from the American Society of Microbiology linking CRISPR and bacteriophages. A review of genes "hitchhiking" in bacteriophages. An introduction to Phollow technology. An overview and discussion of the Phollow technology discussed in this podcast (paywalled). A Phollow related publication also discussed during the podcast. The Wiles laboratory, where Dr. de Ora Ortiz and colleagues developed the Phollow technology. Dr. Travis Wiles' episode of #MattersMicrobial. The Secor laboratory, where Dr. de Ora Ortiz currently works. Dr. de Ora Ortiz's LinkedIn profile. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #120: Bacterial Interactions among Oral Microbes	29 Dec 2025	01:04:49
Matters Microbial #120: Bacterial Interactions among Oral Microbes December 29, 2025 For Episode 120, we welcome Dr. Batbileg Bor, Associate Professor at the ADA Forsyth Institute, to the #QualityQuorum. He joins us to discuss some of the oral community's most enigmatic members: microbes that dwell on other microbes and potentially influence our own health. Host: Mark O. Martin Guest: Batbileg Bor Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a fun video about #LuxArt that Dr. Jennifer Quinn and I made for Harvard University's Microbial Sciences Initiative in 2024. Here is a wonderful essay about Dr. Rita Colwell. Here is a link to her fascinating book about her life. A blog overview of the amazing Deinococcus radiodurans. A fine article about the "artwork" that Paenibacillus creates when it forms colonies. Here is the video that two of my #Bio350 #Micronauts made…a parody of Vanilla Ice's "Ice, Ice, Baby" but about microbiology. Here is a link to the #MattersMicrobial podcast involving the fascinating work of Dr. Jessica Mark Welch on the oral microbiome. A review article on predatory bacteria. An overview of the CPR (Candidate Phyla Radiation), both prominent and mysterious. A recent article by Dr. Bor and colleagues describing the "microbial dark matter" seemingly everwhere…even in the human mouth. An introductory profile on TM7, Saccharibacteria. A solid early review of TM7, by Dr. Bor and colleagues. Dr. Bor and colleagues' early article about TM7, discussed in today's podcast. Dr. Bor and colleagues' article describing interesting interactions between the epibiont and the basibiont, described in today's podcast. Here is a related article. An article by Dr. Bor and colleagues describing the two Type IV pili systems of Saccharibacteria. A fascinating article by Dr. Bor and colleagues describing how TM7 can modulate the responses of animals in different ways, discussed on the podcast. Dr. Bor's LinkedIn profile. Dr. Bor's faculty page at the ADA Forsyth Institute. Dr. Bor's laboratory website with fabulous images to enjoy. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #119: Investigating Microbial "Dark Matter"	22 Dec 2025	01:01:41
Matters Microbial #119: Investigating Microbial "Dark Matter" December 22, 2025 Today Dr. Julia Willett, Assistant Professor in the Department of Microbiology and Immunology at the University of Minnesota, joins the #QualityQuorum to discuss how to investigate unknown genes found in nearly every bacterial genome. Call it Microbial Dark Matter! Host: Mark O. Martin Guest: Julia Willett Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Microbial "Dark Matter"—unknown genes in microbial genomes. The process of annotation. An article about the "Y-ome" or understanding "uncharacterized" genes. The smallest independently growing (and engineered) bacterium, JCVI-syn3.0. It still has many "uncharacterized" but necessary genes. An essay on Enterococcus faecalis. Diseases caused by Enterococcus. The concept of the pathobiont. Dr. Arturo Casadevall's thoughts on the term "pathogen." The use of transposon mutagenesis to create "knock outs" of bacterial genes. Array transposon mutagenesis. Here is an article coauthored by Dr. Willett on that topic. The Alpha Fold program for predicting gene function. A webinar describing "Microbial Dark Matter" by Dr. Willett. Dr. Willett's faculty website. Dr. Willett's laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #118: Biofilms Everywhere!	16 Dec 2025	01:03:51
Matters Microbial #118: Biofilms Everywhere! December 15, 2025 Today Dr. Matthew Fields, Director of the Center for Biofilm Engineering at Montana State University, joins the #QualityQuorum to discuss ubiquitous microbial biofilms. These biofilms touch so many aspects of life on Earth, ranging from human health to engineering issues! Host: Mark O. Martin Guest: Matthew Fields Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The website for the American Society for Microbiology's Conference for Undergraduate Educators. Highly recommended! The must-read story of Angelina Hesse, and the first use of agar to solidify microbiological media. Here is a Kickstarter project involving promoting this important piece of microbiological history. And here is a video made by former podcast guest Dave Westenberg on the Hesse agar story. An engaging video for budding #Micronauts explaining the general concept of quorum sensing in bacteria. A video overview of biofilms on Earth. Perhaps we should call Earth "Planet Biofilm"! Here is an older review of biofilms that is very easy to read and fun to think about. Here is a newer review of the impact that biofilms can have in health, agriculture, industry, and ecology. A video interview with the late "father" of biofilm research, William J. Costerton. The concept that stromatolites are fossilized biofilms. A video describing the biofilm "life cycle." Recent developments in the details of how biofilms form. An article on biofilms and evolution of multicellularity. Previous podcast guest Dr. Vaughn Cooper's "Evolving STEM" outreach project that places biofilms front and center. The challenge of antibiotic resistance and biofilms. The website of the Center for Biofilm Engineering at Montana State University. There is so much to see here, at every level. It is a grand resource for anyone interested in biofilms. The Center for Biofilm Engineers "fact page" on biofilms. Dr. Fields' research page, where you can find information about the kinds of projects discussed today. An engaging video from Dr. Fields institution on biofilms. Dr. Fields' faculty page. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #117: Cancer Virus Hunters and Molecular Biology	08 Dec 2025	01:04:14
Matters Microbial #117: Cancer Virus Hunters and Molecular Biology December 8, 2025 Today Dr. Gregory Morgan, Professor in the School of Humanities, Arts, and Social Sciences at Stevens Institute of Technology, joins the #QualityQuorum to discuss how cancer causing viruses advanced molecular biology as described in his recent book Cancer Virus Hunters. Host: Mark O. Martin Guest: Gregory Morgan Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to Dr. Morgan's book on the topic discussed today. A lovely interview with Dr. Morgan about his book. A great history of molecular biology, "Eighth Day of Creation" by Horace Freeland Judson. The History and Philosophy of Science program at the University of Pittsburgh. An overview of the Rous Sarcoma Virus. A biography of Dr. Peyton Rous. A video describing how RSV causes cancer by "stealing" normal genes. How some viruses may contribute to the development of cancer. Here is another video on that topic. The field of tumor virology. A really wonderful video on the genetic origin for cancer. An overview of oncogenes and protooncogenes. A video exploring how proto-oncogenes become oncogenes, and can contribute to the development of cancer. The concept of "contagious cancer" that is rare but exists. The story of papilloma viruses and "jackalopes." The history of Cold Spring Harbor Laboratory. An overview of retroviruses. Retroviruses and FeLV. Blue chicken eggs and ancient retroviruses. A summary for novice #Micronauts. Mammalian (including human) placenta and ancient retroviruses. Nixon's "War on Cancer." An overview of the src gene. An overview of the ras gene. An overview of the p53 gene. A video explainer of the enzyme reverse transcriptase. A biography of Howard Temin. A biography of David Baltimore. The story of Human Papillovirus (HPV) and cancer. Dr. Morgan's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #116: Microbes in the Concrete Instead of the Abstract	14 Nov 2025	01:05:56
Matters Microbial #116: Microbes in the Concrete Instead of the Abstract November 14, 2025 Today Dr. Julie Maresca, Associate Professor in the Department of Chemistry at the SUNY College of Environmental Science and Forestry joins the #QualityQuorum to discuss how bacteria can interact with a ubiquitous part of modern life: concrete! Host: Mark O. Martin Guest: Julie Maresca Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Hartiful, the vendor that makes the enamel pins I often show on the podcast. An overview of microbes and the "built environment." An article about how concrete is made. A video on how concrete is made. The concept of "self repairing" concrete. An overview of the microbial limits to life with regard to pH. A description of alkalinophilic bacteria. Biofilms that form on concrete. Difficulties in obtaining DNA from rock. An overview of oligotrophic microbes. The alkali-silica reaction in concrete. Challenges of road salt and concrete. An overview of halophilic microbes. An overview of xerophilic microbes. The concept of SLiME communities. The term aeonophiles. Is "Roman" concrete self-repairing? A company that produces "microbial concrete." An article relevant to today's discussion by Dr. Maresca and colleagues. Dr. Maresca's faculty website. Dr. Maresca's wonderful and artistic research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #115: Suiting Up Against Bacterial Predators!	07 Nov 2025	01:00:38
Matters Microbial #115: Suiting Up Against Bacterial Predators! November 6, 2025 Today Dr. Hannah Ledvina, Assistant Professor in the Molecular, Cellular, and Developmental Biology Department at the University of Michigan joins the #QualityQuorum to discuss how bacteria can protect themselves against predators in unusual ways . . . including a type of armor! Host: Mark O. Martin Guest: Hannah Ledvina Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The "Giant Microbes" website. A prompt for my course: an article on "Animals in a Microbial World," with so many interesting examples. Here is a summary for novice #Micronauts. A prompt for my course: an article by the late, great Lynn Margulis on the nature of kefir grains and the definition of multicellularity and the organism. A prompt for my course: an article on hyperpolyploidy in bacteria. An explanation of "genomic islands." A link to a previous guest of #MattersMicrobial, Dr. Laura Williams, discussing Bdellovibrio and undergraduate based research. An overview of predatory bacteria. Here is a more recent overview. An overview of the predator Myxococcus. A wonderful video showing the predatory process of Myxococcus. A fine review of the predator Bdellovibrio. A video of the life cycle of Bdellovibrio. Some work by Dr. Koval and colleagues suggesting that aspects of the outer cell wall is not involved with resistance to Bdellovibrio. Recent VERY exciting work suggesting that there is indeed a receptor on bacteria that Bdellovibrio can recognize. Here is a short summary of that work. Could Bdellovibrio become a "living antibiotic"? A reminder from Drs. Kolter and Losick that bacteria in the laboratory can be quite different from their relatives in nature. The article under discussion on this podcast by Dr. Ledvina and colleagues. Here is an editorial summary on the article. An article on curli proteins in bacteria. An article on amyloid like proteins in bacteria. A video by Dr. Ledvina on the research interests of her group. Thoughts on an "immune system" for bacteria. Dr. Ledvina's faculty website. Dr. Ledvina's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #114: A Tongue-n-Cheek Look at the Oral Microbiome	31 Oct 2025	01:08:26
Matters Microbial #114: A Tongue-n-Cheek Look at the Oral Microbiome October 31, 2025 Today Dr. Jessica Mark Welch, Professor at the ADA Forsyth Institute joins the #QualityQuorum to discuss the complex and interactive microbial communities living unseen within our mouths . . . and what those communities can tell us. Host: Mark O. Martin Guest: Jessica Mark Welch Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to the very funny Carisa Hendrix's character "Lucy Darling." I think I made a #Micronaut out of her! A link to the wonderful microbiological art of Dr. Lizah van der Aart. An overview of FISH technology for visualizing DNA and microbes. A reference to R2A medium which helps grow water associated microbes. The anatomy of the human tongue. The infamous and very interesting article describing how microbes are transmitted between partners via kissing. An overview of the oral microbiome. The relationship between oral microbiota and blood pressure. An article by Dr. Mark Welch and colleagues describing a method for visualizing oral microbial communities. An article by Dr. Mark Welch and colleagues about how her techniques can study the kelp microbiome microbiogeography. An article by Dr. Mark Welch and colleagues about the oral microbiome. An article by Dr. Mark Welch and colleagues about the unusual "corncob" microbes to be found on the human tongue. An article by Dr. Jo Handelsman and colleagues describing the THOR soil community, in which even a few members create very diverse responses to the environment. An article by Dr. Mark Welch and colleagues about the role of mucus in the oral microbiome. An overview of the Forsyth Institute and its mission. The Human Oral Microbiome Database website. The website for Dr. Mark Welch. A fun video snippet with Dr. Mark Welch. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #113: Microbes That Swim, Swarm, Stand Up—and 'Walk'	24 Oct 2025	01:00:17
Matters Microbial #113: Microbes That Swim, Swarm, Stand Up—and 'Walk' October 24, 2025 Today Dr. Joshua Shrout, Professor of Civil and Environmental Engineering and Earth Sciences at the University of Notre Dame joins the #QualityQuorum to discuss the work of his research team on sociomicrobiology. This includes how bacteria sense a surface, move together in groups, and communicate with one another. Host: Mark O. Martin Guest: Joshua Shrout Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a wonderful video about the late great Dr. Esther Lederberg. Here is another article on that same subject. Here is an article about prodigiosin synthesis and Serratia marcescens. An introduction to the concept of sociomicrobiology. An overview of bacterial swarming. Here is a wonderful swarming video. An overview of bacterial swimming in liquid. An article about group/social motility in Myxococcus. A fine video explaining the amazing bacterial flagellar motor. An article about Vibrio parahaemolyticus and swarming. An overview of quorum sensing. Bacteria cultivated in the laboratory undergo mutational changes during "domestication." Pigments produced by Pseudomonas, including pyoverdin and pyocyanin. An article from Dr. Shrout's laboratory group describing interactions between Pseudomonas and Enterococcus described in this episode. The Type IV pili-based motility system. An article from Dr. Shrout's laboratory describing how Pseudomonas can "walk" on one pole during swarming. Here is a video from Dr. Shrout's laboratory showing Pseudomonas "walking" on their poles. An overview video of the Shrout laboratory's research interests. Dr. Shrout's faculty website. Dr. Shrout's truly beautiful research website. There are wonderful microbial videos there. Very much worth your time. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #112: Bacterial Size, Stress, and Antibiotic Resistance	17 Oct 2025	01:04:30
Matters Microbial #112: Bacterial Size, Stress, and Antibiotic Resistance October 17, 2025 Today Dr. Petra Levin, the George and Irene Freiberg Professor of Biology at Washington University in St. Louis joins the #QualityQuorum to discuss her work with bacterial cell size, environmental stress on bacteria, and antibiotic resistance. Host: Mark O. Martin Guest: Petra Levin Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of the periplasm, found in Gram negative bacteria. An overview of beta-lactam antibiotics. The field of quantitative microbiology. An overview of B. subtilis. An overview of E. coli. An overview of Klebsiella. The biography of Barbara McClintock, "A Feeling for the Organism." A video explanation of the lac operon of E. coli. The LTEE program (Long Term Evolution Experiment) founded by Dr. Rich Lenski. The nomenclature of monoderm and diderm bacteria. A video explanation of peptidoglycan in bacteria. Penicillin binding proteins (PBP) and antibiotic resistance. A video about cell division in E. coli. A famous article coauthored by Dr. Elio Schaechter that describes cell growth and cell size in bacteria. A related article by Dr. Levin and colleagues. An overview of ESKAPE bacteria. An article from Dr. Levin's research group describing the relationship between pH and antibiotic resistance. An article about persister cells and their relevance to antibiotic resistance. Dr. Levin's faculty website. Dr. Levin's very interesting laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #111: Shocking Tales of Metal-Loving Microbes	10 Oct 2025	01:09:19
Matters Microbial #111: Shocking Tales of Metal-Loving Microbes October 10, 2025 Today Dr. Jeff Gralnick, Professor of the Department of Plant and Microbial Sciences at the University of Minnesota joins the #QualityQuorum to tell us a shocking story about how his research group studies the relationship between electrons, microbes, and metals. Host: Mark O. Martin Guest: Jeff Gralnick Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An article about Nobel Prize winner Albert Szent-Györgyi. The Soudan Formation Iron Mine discussed during the podcast. An article on Banded Iron Formations. An article about the Oxygen Crisis early in Earth's history. An overview of the bacterium Shewanella. An overview of the bacterium Geobacter. An overview of microbial redox reactions. The "bacterial battery" we discussed: the Mudwatt. An article on benthic microbial fuel cells. An article on extracellular electron transfer by bacteria. The laboratory of Dr. Daniel Bond at the University of Minnesota, and colleague of Dr. Gralnick's. An essay on microbial nanowires. An essay on cable bacteria, which was the topic of #MattersMicrobial podcast #101 with Dr. Nicole Geerlings. The new field of electromicrobiology. The relationship between Shewanella and fish! An article by Dr. Gralnick and colleagues on the Shewanella and fish (and bacteriophage) association. The article about Jon Beckwith (by Howard Shuman) discussed in the podcast: "With Toothpicks and Logic." Dr. Gralnick's faculty website. Dr. Gralnick's laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #110: Enumerating the Microbiome	03 Oct 2025	01:06:27
Matters Microbial #110: Enumerating the Microbiome October 3, 2025 Today Dr. Sean Gibbons, Associate Professor at the Institute for Systems Biology, returns to the #QualityQuorum to tell us about how he and his colleagues are able to listen very carefully to the microbiome to uncover important hints about health. Host: Mark O. Martin Guest: Sean Gibbons Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is the article from Dr. Norm Pace and coworkers on the showerhead microbiome referenced in the podcast. Here is a nonspecialist summary of Dr. Pace's work on the showerhead microbiome and mycobacteria. Here is a link to a prior episode of this podcast with Dr. Ameet Pinto on microbiology of the water supply. Here is Dr. Gibbon's earlier visit to this podcast. An overview of the difference between microbiome and microbiota. An article about the "misnumbering" of the number of microbial to human cells in people. Here is a nonspecialist summary. An overview of metagenomics. An overview of qPCR. An overview of flow cytometry. Plato's Allegory of the Cave, discussed in this podcast. A cautionary tale about determining a cancer microbiome, as discussed in this podcast. An article by Dr. Gibbons and colleagues described in this podcast about how to estimate microbial biomass directly. An article by Dr. Gibbons and colleagues described in this podcast about how to estimate microbial growth rates in the human gut using metagenomics. An article by Dr. Gibbons and colleagues described in this podcast about how to use metagenomics to determine dietary habits. The website for Dr. Gibbon's research group. The faculty website for Dr. Gibbons at ISB. Courses on microbiome sciences online at ISB. The website for Institute for Systems Biology. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #109: Bat-Crazy About Rabies	26 Sep 2025	00:56:52
Matters Microbial #109: Bat-Crazy About Rabies September 26, 2025 In honor of World Rabies Day, Dr. Rodney Rohde, Regents Professor at Texas State University, joins the #QualityQuorum to discuss rabies and some of the strategies used to limit the influence of that devastating viral disease. Host: Mark O. Martin Guest: Rodney Rohde Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of rabies from the CDC. A historical overview of rabies and Louis Pasteur. The global impact of rabies. Bats and rabies. A podcast exploring rabies and myths about vampires and werewolves. A wonderful video about rabies SO worth your time. A video with three physicians about rabies. A detailed review of rabies and the rabies virus. The lifecycle of the rabies virus. Various tests for rabies. The vaccines for rabies. Rabies research at the CDC. Use of an oral rabies vaccine to eliminate epizootic rabies in coyotes and gray foxes in Texas. Information about World Rabies Day. The Contagion Live website, including podcasts by Dr. Rohde. A video from Dr. Rohde about medical laboratory science. A video from Dr. Rohde about rabies. Dr. Rohde's biography from the American Society for Microbiology. Dr. Rohde's faculty website. Dr. Rohde's personal website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #108: Neanderthal Oral Health, Ancient Bacteria and DNA	19 Sep 2025	01:09:22
Matters Microbial #108: Neanderthal Oral Health, Ancient Bacteria and DNA September 19, 2025 Today, Dr. Laura Weyrich, Associate Professor of Anthropology at Pennsylvania State University, joins the #QualityQuorum to discuss the paleo oral microbiome! We will learn if our ancestors had the same kind of resident microbes as we do. In addition, we will learn about ancient DNA and what it can tell us. Host: Mark O. Martin Guest: Laura Weyrich Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An obituary for my late and much missed microbiologist friend, Dr. Kimberly Walker. A link to Episode #9 of #MattersMicrobial, with Sebastian Cocioba. The ethics of collecting samples from deceased humans, both ancient and modern. An overview of the efforts to study ancient DNA. Here is another review on that topic. The importance of proper controls for the study of low DNA abundance samples—the famous "kitome" often observed. Here is an article by Dr. Weyrich and colleagues on this topic, as well. A recent article using human bones to detect Yersinia pestis, the causative agent of plague. An overview of the oral microbiome. An article describing how dental calculus can be used to recover ancient DNA. An article by Dr. Weyrich and colleagues describing the human oral microbiome pre and post Industrial Revolution in Great Britain. A video describing our Neanderthal ancestors. An article by Dr. Weyrich and colleagues describing the Neanderthal oral microbiome and related issues. A fine video by Dr. Weyrich describing her research program. Dr. Weyrich's faculty website. Dr. Weyrich's research team website (SO INTERESTING). Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #107: Listeria Sprouting Hysteria?	11 Sep 2025	01:01:40
Matters Microbial #107: Listeria Sprouting Hysteria? September 11, 2025 Today, Dr. Lisa Gorski, a microbiologist and food safety consultant recently retired from the US Department of Agriculture, Agricultural Research Service, joins the #QualityQuorum to discuss the facts about the disease causing bacterium named Listeria. We will learn about the organism, the disease listeriosis, and food safety. Host: Mark O. Martin Guest: Lisa Gorski Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A description of the ice nucleation phenomenon carried out by many bacteria. An out of print book by Dr. Jo Handelsman that explained the ice nucleation experiment I often use when I teach. An overview of ice nucleation protein. A very nice video demonstration of ice nucleation activity I created many years ago with Puget Sound students. The relationship between ice nucleation protein and the commercial substance "SnowMax." Information from the Centers for Disease Control on Listeria. A description of listeriosis, caused by Listeria. A cute plush toy depicting Listeria, by the Giant Microbes company. A recent review article on Listeria and listeriosis. A video depicting "actin rockets" allowing Listeria to move within eukaryotic cells. A review article on actin-related motility of intracellular bacteria. A description of a recent Listeria outbreak. Advice for consumers regarding avoiding listeriosis. The United States Department of Agriculture group on food safety and surveillance. Articles by Dr. Gorski and colleagues on topics under discussion today. Dr. Gorski's LinkedIn profile. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #106: Cells Without Walls – Full-Frontal Bacteria	06 Sep 2025	00:59:25
Matters Microbial #106: Cells Without Walls – Full-Frontal Bacteria September 6, 2025 Today, Dr. Dennis Claessen of Leiden University's Institute of Biology joins the #QualityQuorum to discuss how some bacteria lose their cell walls, the costs and advantages of that strategy, and how such cells can shed light on antibiotic resistance and even pathogenesis! Host: Mark O. Martin Guest: Dennis Claessen Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Website for the Institute for Biology at Leiden University in the Netherlands. The website of Micropia, the world's best known (and perhaps only) museum devoted to microbial life, in Amsterdam, the Netherlands. The "Tardigrade Chair" at Micropia. The art of Dr. Lizah van der Aart. A video about the cell wall of bacteria. A useful overview of the cell wall of bacteria. A useful review article about the cell membrane of bacteria. An overview of peptidoglycan. The discovery of L-forms of bacteria, and Emmy Klieneberger-Nobel, who named them in 1935. A review article on L-forms (cell wall deficient) bacteria. An article relating L-forms of bacteria and the ability to resist certain antibiotics. Here is another article. An article suggesting that L-forms could shed light on the origins of life. An article suggesting that L-forms are a strategy for dealing with stress. An article from Dr. Claessen's research group showing that L-forms of bacteria are often resistant to bacteriophage infection—and in a reversible fashion. A video presentation by Dr. Claessen. The faculty website of Dr. Claessen. The research website for Dr. Claessen's group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #105: Snails Farming Bacteria in the Deep Sea	29 Aug 2025	01:02:30
Matters Microbial #105: Snails Farming Bacteria in the Deep Sea August 29, 2025 Let's take a deep dive into chemoautotrophy! Today, Dr. Roxanne Beinart, Associate Professor of Oceanography at the University of Rhode Island, joins the #QualityQuorum to discuss how some marine creatures use bacterial symbioses to provide organic compounds for growth and reproduction. Host: Mark O. Martin Guest: Roxanne Beinart Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An appreciation of the late Dr. Moselio (Elio) Schaechter from his friends at the blog "Small Things Considered." A video from This Week in Microbiology appreciating Elio Schaechter. A video describing deep sea symbioses. A video by the great Dr. Colleen Cavanaugh about chemoautotrophy/chemosynthesis. An overview of chemoautotrophic strategies in the ocean. An overview of hydrothermal vents. A video review of thiotrophic (sulfur based) symbiotic associations. A video about hydrothermal vent exploration. A review of hydrothermal vent communities. Alvinella, the extremophilic bristleworm discussed in this episode (includes videos). An article by Dr. Beinart and colleagues, describing how a hydrothermal vent community is disrupted by a volcanic eruption. A report on the 2020 submarine volcano eruption discussed in this episode. An interesting article about studying deep sea symbioses, coauthored by Dr. Beinart. A great video by Dr. Beinart about her research. Dr. Beinart's research team website. Dr. Beinart's faculty webpage. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #104: Antibiotic "Tolerance" and Biofilms	22 Aug 2025	01:02:48
Matters Microbial #104: Antibiotic "Tolerance" and Biofilms August 21, 2025 Today, Dr. Boo Shan Tseng, Associate Professor at the University of Nevada Las Vegas School of Life Sciences, joins the #QualityQuorum to discuss bacterial biofilms and antibiotic tolerance. Host: Mark O. Martin Guest: Boo Shan Tseng Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video overview of biofilms. A comprehensive review article on biofilms. An article describing the impact biofilms have on disease. An article describing the impact of biofilms on implanted medical devices. A link to the Center for Biofilm Engineering at Montana State University that has MANY links of interest. An overview of biofilm development. An overview of confocal laser microscopy. Studying biofilms in flow cells. An article about the role proteins play in biofilm formation, which intersects with the Tseng group's research. The technique of single cell RNA seq. The technique of mRNA-FISH. An article about porins in bacteria, and how that can relate to antibiotic resistance. An article by Dr. Tseng and coworkers on the eDNA and biofilms discussed today. A lovely video of Dr. Tseng talking about the research she and her colleagues carry out in the laboratory. Dr. Tseng's biography from the American Society for Microbiology. Dr. Tseng's laboratory group website with wonderful links and images. Dr. Tseng's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #103: Giant Bacteria and Bigger Questions	15 Aug 2025	01:04:01
Matters Microbial #103: Giant Bacteria and Bigger Questions August 14, 2025 Today, Dr. Jean-Marie Volland, Assistant Professor at the University of California in Santa Barbara joins the #QualityQuorum to discuss the discovery and analysis of the (so far) largest bacterium known: Thiomargarita magnifica, which can be a centimeter long! Definitely #OMG and #WTM! Host: Mark O. Martin Guest: Jean-Marie Vollard Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a review article discussing the environmental persistence of antibiotic resistance genes. Here is a link to Episode 41 of this podcast, with Dr. Esther Angert, on the wily ways of Epulopiscium. A review article regarding "giant bacteria." A video explaining the surface area versus volume issue discussed on this podcast. An interesting article exploring how much "territory" is within a bacterial cell; this is relevant to bacterial polyploidy. A review of Epulopiscium, the first of the giant bacteria described. Here is a video of Epulopisicum. An article describing polyploidy in Epulopiscium. A review of Thiomargarita nambiensis, another giant bacterium with an interesting strategy. Here is a video of T. nambiensis. An essay from "Small Things Considered" about the very, very strange world of Achromatium, which is so worth your time. The first report of Thiomargarita magnifica, the world's largest bacterium (thus far) by Dr. Volland and coauthors. Here is a report on this discovery for novice micronauts. A great review about giant microbes by Dr. Volland. A more recent article on T. magnifica by Dr. Volland and colleagues. A video regarding T. magnifica. A video by Dr. Volland describing T. magnifica work. A lovely essay regarding how Dr. Volland and family trekked California searching for giant microbes. Don't miss! The research lab website for Dr. Volland and colleagues, with so much interesting information. The faculty website for Dr. Volland at UC Santa Barbara. Intro music is by Reber Clark
	Matters Microbial #102: Teaching Through the Issues with Microbes!	01 Aug 2025	01:03:59
Matters Microbial #102: Teaching Through the Issues with Microbes! July 31, 2025 Today, Dr. Davida Smyth, Professor of Biology and Deputy Director of the National Center for Science and Civic Engagement at Texas A&M University-San Antonio joins the #QualityQuorum to discuss her impressive work using microbiology to engage students at the intersection of cutting edge research and current events. #MicrobialLiteracy! Host: Mark O. Martin Guest: Davida Smyth Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The American Society for Microbiology Carski Award website. The American Society for Microbiology Distinguished Lecturer website. The concept of "classroom agreements." The 10:1 (microbial cells to human cells) story, and a related article. The 3-2-1 approach to learning in the classroom. Dr. Smyth's "How Toilets Changed the World" class. The American Society for Microbiology Curriculum Guidelines. The National Science Foundation's "Vision and Change" website describing improvements in biology education. The American Society for Microbiology profile for Dr. Smyth. A video seminar by Dr. Smyth describing open science in undergraduate education. The website for the National Center for Science and Civic Engagement. Dr. Smyth's faculty website. Dr. Smyth's superb research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #101: Electrifying News about Cable Bacteria	25 Jul 2025	01:04:20
Matters Microbial #101: Electrifying News about Cable Bacteria July 25, 2025 Today, Dr. Nicole Geerlings from the University of Vienna in Austria joins the #QualityQuorum to discuss some of the wonderful work she and colleagues have carried out studying the wild, weird, and wonderful world of cable bacteria, which can conduct electricity over microbially enormous distances! Definitely time for #OMG and #WTM! Host: Mark O. Martin Guest: Nicole Geerlings Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode This just became available: a wonderful short introduction to day's topic, the cable bacteria, from Asimov Press. It is an absolute must read for everyone interested. Here is a link to the Summer Science Program, a wonderful outreach program for high school juniors. An essay about Nobel Prize winning Albert Szent-Györgyi, who stated that life was a matter of electrons finding a place to rest. Here is a short video introduction to his work. A video introduction to microbial metabolism. A video introduction to electron transport. Remember that bacteria and archaea are VERY skilled at using different electron donors and acceptors than eukaryotic life. The really fun concept of the "Jagendorf Jump," showing electron transport vs. pH in chloroplasts. An overview of the microbial fuel cell concept. Here is a nice overview I highly recommend. A commercial source for you to build your own microbial fuel cell. A DIY approach to building a MFC. An ESSENTIAL overview to the idea of electrons in microbial sediments. A review article about cable bacteria. Here is another fine review. This is a third great introduction to cable bacteria. And here is a video overview. An article by Dr. Geerlings and colleagues describing cable bacteria for new #Micronauts. HIGHLY RECOMMENDED. An review of stable isotope probing in microbiology. Here is a video seminar using SIP in microbiology. An overview of Nano-SIMS and how it is used in microbiology. Here is another review. A deeply wonderful article by Dr. Geerlings and colleagues suggesting that inactive cells with the "microbial cable" are still conducting electrons! Dr. Geerlings postdoctoral scholar website. Links and References on Cable Bacteria from Dr. Geerlings: 1. Here is a website from the group of Prof. Dr. Filip Meysman from the University of Antwerp, which includes a great video on the electron conductivity of cable bacteria. 2. The first paper describing redox half-reactions separated by long-distance electron transport. Nielsen, L. P., Risgaard-Petersen, N., Fossing, H., Christensen, P. B., and Sayama, M. (2010). Electric currents couple spatially separated biogeochemical processes in marine sediment. Nature 463, 1071–1074. doi: 10.1038/nature08790 3. The paper describing the discovery of cable bacteria. Look into the supplemental material for the excellent experimental set-up to prove that the cable bacteria are the ones doing the long-distance electron transport. Pfeffer, C., Larsen, S., Song, J., Dong, M., Besenbacher, F., Meyer, R. L., et al. (2012). Filamentous bacteria transport electrons over centimetre distances. Nature 491, 218–221. Doi: 10.1038/nature11586 4. A paper that dives into the conductivity of the cable bacteria network and shows that these fibres can conduct electrons just as well as a copper wire. Meysman, F. J. R., Cornelissen, R., Trashin, S., Bonné, R., Martinez, S. H., van der Veen, J., et al. 2019. A highly conductive fibre network enables centimetre-scale electron transport in multicellular cable bacteria. Nat. Commun. 10:1–8. doi: 10.1038/s41467-019-12115-7 5. This paper describes how cable bacteria activity generates a layer of iron oxyhydroxides on the top of the sediment layer and how this delays the release of sulfide into the water column for several weeks in a seasonally hypoxic basin in the Netherlands. Seitaj, D., R. Schauer, F. Sulu-Gambari, et al. 2015. "Cable Bacteria Generate a Firewall Against *Euxinia* in Seasonally Hypoxic Basins." Proceedings of the National Academy of Sciences of the United States of America 112: 13278–13283. 6. This paper describes how the catabolic division of labor is coupled to an anabolic division of labor where cells reducing oxygen cannot grow and therefore provide a "community service" for the rest of the filament. Nicole M. J. Geerlings, Cheryl Karman, Stanislav Trashin, Karel S. As, Michiel V. M. Kienhuis, Silvia Hidalgo-Martinez, Diana Vasquez-Cardenas, Henricus T.S. Boschker, Karolien de Wael, Jack J. Middelburg, Lubos Polerecky, and Filip J.R. Meysman. Division of labor and growth during electrical cooperation in multicellular cable bacteria. Proc. Natl. Acad. Sci. U.S.A. 117, 5478–5485. Doi: 10.1073/pnas.1916244117 Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #100: What's the Buzz on Phage Therapy for Honeybees?	17 Jul 2025	01:03:30
Matters Microbial #100: What's the Buzz on Phage Therapy for Honeybees? July 14, 2025 Today, Dr. Heather Hendrickson from the University of Canterbury in New Zealand joins the #QualityQuorum to discuss the research she and her team are conducting on bacteriophage therapy to protect vulnerable honeybees from bacterial infections. Host: Mark O. Martin Guest: Heather Hendrickson Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is the website for a former undergraduate research student of mine, Dr. Paula Welander, now a professor and administrator at Stanford University. Yes, I am proud. Here is a link to another former undergraduate research student of mine, Dr. Krista Venecia Edmiston, now a professor at California Health Sciences University. Yes, I am proud. A review on cell shape in bacteria. A review on the cytoskeleton of bacteria and archaea. I am a great admirer of Dr. John Roth, and his clearheaded and direct approach to microbial genetics. Here is his academic website with many publications. An article about the causative agent of American Foulbrood, Paenibacillus larvae. An overview of American Foulbrood's impact on honeybees. The honeybee lifecycle. Beemites and honeybees. A video overview of bacteriophage therapy against bacterial diseases. An explainer of bacteriophage plaques. A video overview of lytic versus lysogenic bacteriophages. Dr. Graham Hatfull and his simply amazing SEAPHAGEs program, teaching so many people about isolating and studying bacteriophages. An article from Dr. Hendrickson's laboratory exploring cell shape in bacteria. An article from Dr. Hendrickson's laboratory explaining the importance of protecting honeybees from American Foulbrood, and the approach her laboratory uses. An article from Dr. Hendrickson's laboratory describing a community based approach to search for bacteriophages of Paenibacillus larvae. An article from Dr. Hendrickson's laboratory analyzing the types of Paenibacillus attacking bacteriophages isolated in New Zealand. An article from Dr. Hendrickson's laboratory describing an improved method for isolating bacteriophages. A truly great video from Dr. Hendrickson some years ago, explaining her research. This is a "must see." Dr. Hendrickson's faculty webpage. Dr. Hendrickson's informative research group website. This section of Dr. Hendrickson's research group website is devoted to outreach, and so very worth your time. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #99: Albert Kluyver—Microbial Unity and Diversity in Metabolism	10 Jul 2025	00:30:46
Matters Microbial #99: Albert Kluyver—Microbial Unity and Diversity in Metabolism July 10, 2025 Today, Dr. Dianne Newman of Caltech joins the #QualityQuorum live at ASM Microbe in Los Angeles, to discuss the role that Albert Kluvyer played in helping microbial scientists to understand the unity and diversity to be found in microbial metabolism. Host: Mark O. Martin Guest: Dianne Newman Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A review article by Roberto Kolter about the history of microbiology. An overview of the "Delft School" of microbiology. Here is another article on that topic. The 1924 article by Albert Kluyver that Dr. Newman references—very much worth you time. A video overview of microbial metabolism. Here is a recent article on that topic. A short biography of Albert Kluyver. Here is another article on that topic. A wonderful 2023 video seminar by Dr. Newman exploring the unity and diversity of microbial metabolism. Much recommended. Dr. Newman's faculty website. Dr. Newman's very impressive research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #98: Nesting Dolls of Endosymbiosis	04 Jul 2025	00:59:38
Matters Microbial #98: Nesting Dolls of Endosymbiosis July 3, 2025 Today, Dr. John McCutcheon of Arizona State University joins the #QualityQuorum to discuss the work he and his research group do to investigate the strategies by which microbes become symbionts of other cells. After all, the mitochondria and chloroplasts of eukaryotic cells, including yours, were once bacteria! Host: Mark O. Martin Guest: John McCutcheon Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video about the symbiosis of Hydra virdissima, which captured my heart when I was young. Look at those symbiotic algae! Here is an overview of this topic. A video describing the Rhizobium – legume nitrogen fixing symbiosis in all of its glory—by my PhD advisor, the great Dr. Sharon Long. Here is an overview of this topic. An appreciation of Paul Buchner's very important book, "Endosymbiosis of Animals with Plant Microorganisms." A wonderful review by Dr. McCutcheon on how symbioses form. A wonderful essay by Ed Yong about an event that made eukaryotic cells possible: how bacteria became mitochondria. A story about an anaerobic protist that lost its mitochondria completely. A bacterial symbiont of mitochondria, the "midichlorian." The recent discovery of a new integrated symbiont that has become an organelle, the nitrosome. The "X-bacteria" and amoebae story. A retrospective on endosymbiosis, and Paramecium based on Tracey Sonneborn's work. An essay on aphids and bacteria. An article on the Moranella/Tremblaya symbiosis. An article on "bacteria inside other bacteria" found in several symbioses, written by Dr.McCutcheon and colleagues. Genomic instability in bacterial endosymbionts. An article on cicadas and bacterial endosymbionts from Dr. McCutcheon and colleagues. An article on mealybugs and bacterial endosymbionts from Dr. McCutcheon and colleagues. Dr. McCutcheon's thoughts on his career path (so worth reading). The Center for Mechanisms of Evolution research institute in which Dr. McCutcheon works. Dr. McCutcheon's faculty website. Dr. McCutcheon's (and his research team's) wonderful research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #97: Microbes in the Air (Way)	27 Jun 2025	01:07:46
Matters Microbial #97: Microbes in the Air (Way) June 27, 2025 Today, Dr. Ari Kozik, Assistant Professor at the University of MIchigan joins the #QualityQuorum to discuss the work she and her research group do to investigate microbes living within the lung and their relationship to health as well as microbiology outreach and representation. Host: Mark O. Martin Guest: Ari Kozik Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A wonderful discussion of airway microbes. A thought provoking article about microbes in our breath! Geography of mouth to lung and relevance to health. Relevance and definition of the term "microaspiration." Some general characteristics of anaerobic bacteria A commercial video explaining the basics of anaerobic chambers An article about the airway microbiome A video overview about biofilms Kombucha sculpture as discussed briefly. A relevant article from Dr. Kozik's and coworkers. A video from This Week in Virology including Dr. Kozik about representation in the microbial sciences (very important to watch). Dr. Kozik's important efforts in science outreach. Dr. Kozik's faculty website. Dr. Kozik's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #96: Molecular Microbiology in High Schools	20 Jun 2025	01:02:52
Matters Microbial #96: Molecular Microbiology in High Schools June 19, 2025 Today, Bob Kuhn, biotechnology teacher at the Fulton County Schools Innovation Academy STEM high school in Alpharetta, Georgia joins the #QualityQuorum to discuss his strategies for teaching molecular microbiology skills and concepts to high school students — and why that matters. Host: Mark O. Martin Guest: Bob Kuhn Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An article on Mr. Kuhn's original microbiological interest: salt marsh foraminifera. Another interest: a video of the beautiful organism Volvox. An overview of the fantastic world of protists. A classroom CURE that Mr. Kuhn uses: the Tiny Earth program. A classroom CURE that Mr. Kuhn uses: the SEAPHAGES program. A classroom CURE that Mr. Kuhn uses: the Evolving Stem program. A classroom CURE that Mr. Kuhn uses: the Discover the Microbes Within program. Mr. Kuhn's classroom received help from the University of Georgia Microscopy Center. A video of the Wolbachia Project with which Mr. Kuhn has collaborated for years. An overview of wonderful and various isopods, including the "roly polies" used in some Wolbachia work. The Journal of Emerging Investigators, in which some of Mr. Kuhn's high school students have published. The LTEE program that studies evolution in E. coli. The Experiment.com program that supported some of Mr. Kuhn's students. The very inspirational MEGAplate video that demonstrates how quickly antibiotic resistance can occur. Innovation Academy STEM program in Georgia, where Mr. Kuhn works with high school students. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #95: Bacteria and Aphids — A Symbiotic Story	13 Jun 2025	01:02:05
Matters Microbial #95: Bacteria and Aphids — A Symbiotic Story June 12, 2025 Today, Dr. Tory Hendry, Associate Professor of Microbiology at Cornell University, joins the #QualityQuorum to tell us about the relationship between plant munching aphids and fluorescent Pseudomonas . . . and why we should care. Host: Mark O. Martin Guests: Tory Hendry Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of siderophores in microorganisms. An essay about aphid life cycle and characteristics. An article describing parthenogenesis in aphids. An essay describing aphids and color vision. The agricultural costs of aphids as pests. An article describing aphids and one type of bacterial symbiont. An overview of microbes of the phyllosphere. An overview of quorum sensing. An overview of pyoverdin, a fluorescent siderophore. An old essay I wrote for the Small Things Considered blog about semiochemicals, bacterial, and insect predation. A nice description of the work Dr. Hendry talked about during today's podcast. The actual article by Dr. Hendry and collaborators. A preprint by Dr. Hendry's research group, following up on the above research. Dr. Hendry's faculty website. Dr. Hendry's research group website (with SO MANY cool projects to think about, including the topic discussed today). Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #94: One Health and Microbiomes Everywhere	06 Jun 2025	01:11:32
Matters Microbial #94: One Health and Microbiomes Everywhere June 5, 2025 Today, Dr. Seth Bordenstein and Dr. Nichole Ginnan of Pennsylvania State University join the #QualityQuorum to tell us about their new publication linking One Health to the myriad microbiomes that exist all around us through the lens of the holobiome—and an opportunity to see the world in a different fashion. Host: Mark O. Martin Guests: Seth Bordenstein and Nichole Ginnan Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Michele Banks microbially themed art can found at her Etsy site. Highly recommended! The paper under discussion today, with Dr. Ginnan as first author. You will see that coauthors include Dr. Bordenstein, and two previous visitors to the #MattersMicrobial podcast! Thank you Erika and Francisco. Dr. Bordenstein's first podcast with #MattersMicrobial for those who missed it. A review of the One Health concept. The One Health Microbiome Center at Penn State. A very clear overview of the holobiont concept and biology, authored by Dr. Bordenstein and colleagues. Another longer review on this topic. The faculty website for Dr. Ginnan. The faculty website for Dr. Bordenstein. The research website for Dr. Ginnan. The research website for Dr. Bordenstein. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #93: Preventing Antibiotic Resistance	29 May 2025	00:49:49
Matters Microbial #93: Preventing Antibiotic Resistance May 29, 2025 Today's episode was an in-person podcast at the University of Texas Austin! Dr. Despoina Mavridou, Assistant Professor of Molecular Biosciences, joins the #QualityQuorum to discuss how her research group improves antibiotic effectiveness by impeding protein folding, and why this matters in the fight against antimicrobial resistance. Host: Mark O. Martin Guest: Despoina Mavridou Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to a wonderful video of the #LuxArt by UT-Austin students during my visit. Please give it watch and enjoy the creativity and positive #MicrobialPR. An effective TED talk by science journalist Maryn McKenna describing the threat of AMR in an accessible fashion. A CDC report on the growing threat of AMR. A review article about antibiotics. An overview of how bacteria become resistant to antibiotics. A very recent review of the cell wall of bacteria—often the target of antibiotics. A video overview of beta-lactam antibiotics and resistance mechanisms. An overview of how protein folding is related to activity of proteins…including AMR gene products. A wonderful article by Dr. Mavridou and coworkers, describing how altering protein folding in bacteria can make them more vulnerable to antibiotics. A less technical version of the above article; well worth your reading. Dr. Mavridou's faculty website. Dr. Mavridou's research group website, which is most interesting. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #92: Microbial Metabolism in Extreme Places	22 May 2025	01:04:15
Matters Microbial #92: Microbial Metabolism in Extreme Places May 22, 2025 Today, Dr. Valerie DeAnda Torres, Assistant Professor of Microbiology and Cell Science at the University of Florida (and National Geographic Explorer), joins the #QualityQuorum to tell us about the research her team does, studying the evolution of metabolic pathways in extreme environments . . . and why these are important to geochemical cycling. Host: Mark O. Martin Guest: Valerie DeAnda Torres Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The Etsy vendor making the beautiful microbial pins I have mentioned. A link to Sebastian Cocobia's site where the beautiful E. coli strains I referenced can be obtained. The beauty and mystery of Paenibacillus colonies. A video showing a colony of Myxococcus consuming a colony of E. coli. A fun video of tardigrades singing "Happy birthday" by a former undergraduate student of mine, Dr. Jake Shaffer. The National Geographic Explorer program, which includes Dr. DeAnda Torres. The deep sea submersible Alvin, in which Dr. DeAnda Torres has dived! An overview of methanogenesis, one of the pathways that Dr. DeAnda Torres' research group studies. A review of biogeochemical cycles in the deep ocean. The work of my former undergraduate research student, Dr. Paula Welander, on membrane biosignatures in ancient rocks. A recent review of the Asgard archaea, that may be our ancient ancestors. Some recent work by Dr. DeAnda Torres and collaborators on the Asgard archaea. One of the research cruises in which Dr. DeAnda Torres participated. During one cruise that included an Alvin dive to a hydrothermal vent, Dr. DeAnda Torres and scientists working with her described their work in this livestream partially in Spanish. Dr. DeAnda Torres will be part of some upcoming collaborative research cruises, seen here. Here is an article and video describing some of the collaborative work Dr. DeAnda Torres carries out, studying microbial breakdown of PFAS chemicals in marine sediment. A link to the faculty website of Dr. DeAnda Torres. A link to the research website of the DeAnda Torres group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #91: You Are What Your Genes Feed Your Microbiome	16 May 2025	01:05:36
Matters Microbial #91: You Are What Your Genes Feed Your Microbiome May 16, 2025 Today, Dr. Emily Davenport, Assistant Professor in the Department of Biology and Huck Institutes of the Life Sciences at Penn State University, joins the #QualityQuorum to tell us about the research her team does, studying how our own genes impact our microbiomes. Host: Mark O. Martin Guest: Emily Davenport Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A description of GWAS ("Genome Wide Association Study"). Here is an introductory video about the concept. An explainer on organoids. An essay about the diversity of the host microbiome (i.e. is there a "healthy" microbiome?). An article of the work of Dr. Sarkis Mazamian on how individual host genes and bacterial genes can impact the microbiome. A nice write up for Dr. Mazamian's work showing how host genes and bacterial genes can work together…or not. An oldish video of how the infant microbiome develops over time by Dr. Rob Knight's research group. An article on the same topic from Dr. Ruth Ley. An essay on the mucosal microbiota, rather than the fecal microbiome. An interesting member of the human microbiome, Akkermansia that might be related to obesity. Another interesting member of the human microbiome, Bifidobacterium, which appears to be associated with host lactose metabolism. Yes, there is a Giant Microbes plush toy. An overview of the impact of host genetics on the microbiome by Dr. Davenport. A definition of heritability. An overview of the Hutterites and how their study has advanced genetics. An explainer of the power of twin studies in genetics. A fascinating article about ancient dental plaque microbiome by Dr. Davenport and others. Dr. Davenport's faculty website. Dr. Davenport's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
	Matters Microbial #90: Using Soil Microbiomes in Sustainable Agriculture	08 May 2025	01:01:36
Matters Microbial #90: Using Soil Microbiomes in Sustainable Agriculture May 8, 2025 Today, Dr. Francisco Dini Andreote, Assistant Professor of Phytobiomes at Penn State, joins the #QualityQuorum to tell us about the microbiome of plants and the soil, and how understanding that relationship can improve agriculture. Host: Mark O. Martin Guest: Francisco Dini Andreote Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of the Type 6 Secretory System of bacteria—almost like a microbial switchblade knife. A wonderful video of the T6SS made by a student in my own microbiology course some time ago. A video introduction to the Rhizobium-legume symbiosis and why you should care about it (by my PhD advisor from long ago, Dr. Sharon Long). A more comprehensive review article on the Rhizobium-legume symbiosis. The chemical signal of geosmin, and how it might be used by other organisms. Ecological succession in the development of sauerkraut. A must read essay by Carl Zimmer likening the human body to a number of ecological niches. The developing field of agroecology. A reminder about the "One Health" concept. Mycorrhizae and plant nutrition. Chemical communication within the soil. A fun remembrance of Norman Borlaug, who urged us to "listen" to plants. An overview of the root microbiome. The "superorganism" concept versus the "holobiome" concept.. Striga, a parasite of crop plants. Chemical communication and Striga. An interesting and relevant publication from Dr. Dini Andreote's research group, describing how the root microbiome could help agriculture. Dr. Dini Andreote's faculty website. Dr. Dini Andreote's very wonderful research team website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

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