Explore every episode of the podcast Last Week in Medicine
| Title | Pub. Date | Duration | |
|---|---|---|---|
| Semaglutide for CVD in Diabetes, PAD, and MASH, Semaglutide vs Tirzepatide, Normal Saline vs Lactated Ringer's, Oxygen Targets for Intubated Patients, Platelet Transfusion Guidelines, Apixaban vs Rivaroxaban | 17 Jun 2025 | 01:05:06 | |
Today we do a round-up of some of the recent semaglutide trials. Does semaglutide ever miss? But what about tirzepatide, which causes even more weight loss? We also review two new critical care trials, FLUID and the UK-ROX, new platelet transfusion guidelines, and a new retrospective study of apixaban vs rivaroxaban vs warfarin. Oral Semaglutide for Diabetes with Cardiovascular Disease or CKD (SOUL) Semaglutide for Peripheral Artery Disease (STRIDE) Semaglutide for MASH (ESSENCE) Semaglutide vs Tirzepatide for Obesity (SURMOUNT-5) Normal Saline vs Lactated Ringers (FLUID) Conservative Oxygen Targets in Mechanically Ventilated Patients (UK-ROX) Platelet Transfusion Guidelines Apixaban vs Rivaroxaban vs Warfarin Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Hydrocortisone for Severe Pneumonia (REMAP-CAP), Intensive BP Control in Diabetes (BPROAD), Aldosterone Synthase Inhibitors for Hypertension (ADVANCE-HTN), Reduced-dose Apixaban for Cancer Associated Thrombosis (API-CAT) | 24 Apr 2025 | 00:56:43 | |
What do you do when most trials suggest benefit for an intervention, but then a new trial suggests harm? We thought steroids in pneumonia was a settled question, but REMAP-CAP had other plans! We also review a new RCT for BP targets in patients with hypertension and diabetes, a new aldosterone synthase inhibitor for hypertension, and reduced dose apixaban for cancer-associated thrombosis. Hydrocortisone for Severe CAP (REMAP-CAP) Predicting Benefit of Corticosteroids in Pneumonia Intensive BP Control in Patients with Diabetes (BPROAD) Lorundrostat for Uncontrolled Hypertension (ADVANCE-HTN) Reduced Dose Apixaban for Cancer Associated Thrombosis (API-CAT) Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Early Vasopressors and Restrictive Fluids in Septic Shock (CLOVERS), Furosemide vs Torsemide in Heart Failure (TRANSFORM-HF), Aspirin vs Enoxaparin after Extremity Fracture (PREVENT CLOT), Haloperidol for ICU Delirium (AID-ICU) | 31 Jan 2023 | 00:51:05 | |
We're back with Season 4! Sorry for the unplanned hiatus. https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| SGLT2 Inhibitors for Acute Heart Failure, SGLT2 Inhibitors vs Metformin, High Dose Dexamethasone for COVID-19 in ICU, Isolated Distal DVT, Monkeypox, Blood Donor Sex and Mortality, Outcomes in Surgeons Who Operate the Night Before | 22 Jul 2022 | 00:44:36 | |
Today we have a couple special guests under the age of 2. Birdie and Gus! https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Restrictive Fluids in Septic Shock, Short vs Standard Antibiotics in Neutropenic Fever, IV Vitamin C for Septic Shock, Hospitalist Workload and Patient LOS, Fluid Bolus for Intubation, General Internist Practice Choices | 24 Jun 2022 | 00:54:50 | |
Today we are joined by Dr. Brian Locke to talk about multiple new critical care trials, including the CLASSIC trial of a restrictive vs standard fluid strategy, the LOVIT trial of vitamin C in septic shock, and the PREPARE-II trial of fluid bolus at the time of intubation to prevent cardiovascular collapse. We also look at whether 72 hours of antibiotics are safe in patients with neutropenic fever, whether hospitalist workload affects patient length of stay, and what kind of careers general internists are pursuing over the last decade. https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Inpatient Management of Opioid Use Disorder, Hep C Treatment in IVDU, Final SOLIDARITY Results for Remdesivir, TAVI for Moderate Risk Severe AS, Mediterranean Diet vs Low Fat Diet, Steroids for IgA Nephropathy, GLP-1s and Gallbladder Disease | 25 May 2022 | 00:58:45 | |
Today we had Dr. Patricia Liu to talk about a new study from Journal of Hospital Medicine on the management of opioid use disorder in the hospital. And then we got a little carried away covering way too many articles! https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| 2022 AHA/ACC/HFSA Heart Failure Guidelines with Dr. James Fang, Guideline Committee Member | 04 May 2022 | 00:32:50 | |
Today, Dr. James Fang, Chief of Cardiovascular Medicine at the University of Utah, and AHA/ACC/HFSA Heart Failure Guideline Committee Member, joins us to talk about the new heart failure guidelines, published in April 2022. We talk about the new classifications, including HF with improved EF and HF with mildly reduced EF, and new recommendations for medical therapy for all the heart failure types. How do you start someone on GDMT? Who should get SGLT-2 inhibitors? How can we get more people on ARNIs? Dr. Fang provides lots of clinical pearls and practical wisdom for applying these new recommendations. Check it out! https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Oral Carbapenem for Complicated UTIs, Awake Proning for COVID-19, 1-2 Months DAPT vs 12 Months DAPT, Low Sodium Diet for Heart Failure, Excess Mortality From COVID-19, IV Iron and Anaphylaxis, Pickle Juice for Cramps in Cirrhosis | 23 Apr 2022 | 00:50:39 | |
Dr. Brian Locke is back to talk about that "nonrandomized" proning trial. We also talk about the new oral carbapenem for UTI trial, whether 1-2 months of DAPT is non-inferior to 12 months of DAPT, whether less than 1500 mg of sodium reduces heart failure hospitalizations, the risk of anaphylaxis from IV iron, and whether pickle juice is effective for treating cramps in cirrhosis. Check it out! https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Reliever-Triggered ICS Therapy for Asthma, Methenamine for UTI Prevention, CT vs Invasive Coronary Angiography, Melatonin for Delirium Prevention, Interpretation of Home COVID Tests, Characteristics of Type 2 MI | 22 Mar 2022 | 01:05:44 | |
Today we have Dr. Brian Locke back on to talk about asthma management and a new trial of reliever-triggered inhaled glucocorticoids for Black and Latinx patients with asthma. Other questions we try to answer: Does methenamine prevent recurrent UTIs in women? Should CT coronary scan be done before invasive coronary angiography? Does melatonin prevent delirium in ICU patients? How good are patients at interpreting home COVID tests? What is the most common cause of type 2 NSTEMI? Give it a listen and find out! https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Paxlovid for COVID-19, Ivermectin Ineffective for COVID-19, One Year Outcomes for ICU COVID-19 Patients, Diagnostic Strategies for Ruling Out PE, Thiamine for Alcohol Use Disorder, Skin Color and Pulse Oximetry | 25 Feb 2022 | 00:42:46 | |
We finally have the published trial results for Paxlovid! We also look at the latest trial showing the ivermectin is ineffective in treating COVID-19 and one year outcomes in ICU COVID-19 patients. We also look at a meta-analysis of trials looking at different diagnostic strategies for ruling out PE, a retrospective study of thiamine use in ICU patients with alcohol use disorder, and a new study on pulse oximetry in people with different skin color. Check it out! https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Balanced Crystalloid vs Normal Saline (PLUS trial), Midline vs PICC, LOLA for Hepatic Encephalopathy, Eat-Walk-Engage Program for Older Inpatients, Post-Discharge Thromboprophylaxis for COVID-19, Mindfulness Training and Burnout | 28 Jan 2022 | 00:49:09 | |
Today we are joined by Dr. Brian Locke to talk about the newest big trial on IV fluids in critically ill patients and a meta-analysis that looks at all the similar trials. Is this question finally settled? https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Ultrasound JVP to Estimate CVP, IV Metoprolol vs Diltiazem for Atrial Fibrillation with RVR, Ischemic Stroke and Bleeding Risk with Apixaban vs Rivaroxaban, Reducing Sleep Interruptions in Hospital, Outpatient Remdesivir, Molnupiravir for COVID-19 | 31 Dec 2021 | 01:11:36 | |
It's our last episode in 2021! This episode we have Dr. Libo Wang and Dr. Jon Harrison on to talk about their new paper in the Annals of Internal Medicine about ultrasound JVP for estimating CVP, validated with right heart catheterization. We also ask them their thoughts on a new meta-analysis looking at metoprolol vs diltiazem for atrial fibrillation with RVR. https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Half Dose DOAC for Long Term VTE Prevention, Biomarker Guided Antibiotics for Sepsis, GPT-4 Assistance for Physicians, Optimal Vasopressin Initiation for Shock, DOAC vs No AC for A fib After Intracerebral Hemorrhage, HFNC vs NIV for Respiratory Failure | 27 Mar 2025 | 01:32:52 | |
For this episode we are joined by EBM guru, Dr. Brian Locke, who deftly breaks down all of our statistics questions. Is half dose DOAC as good as full dose DOAC for preventing VTE, and does it reduce bleeding risk? Can procalcitonin reduce duration of antibiotics for infections without compromising mortality rates? Can LLMs like GPT-4 help physicians manage patients better? Can reinforcement learning models predict when to start vasopressin in patients with septic shock? What is the risk of resuming anticoagulation in patients with atrial fibrillation and prior intracerebral hemorrhage? Is high flow nasal cannula as good as non-invasive ventilation for different types of respiratory failure? We answer all these questions and more! Half Dose DOAC for Long Term VTE Prevention (RENOVE) Biomarker-Guided Antibiotic Duration (ADAPT-Sepsis) GPT-4 Assistance for Physician Performance Optimal Vasopressin Initiation for Septic Shock (OVISS) DOACs for A fib after ICH (PRESTIGE-AF) High Flow Nasal Cannula vs NIV for Respiratory Failure (RENOVATE) Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Chlorthalidone in CKD, Factor XI Inhibition for VTE Prevention, Untreated Subsegmental PE and Risk of Recurrent VTE, Rivaroxaban and GI Bleeding, Mental Stress Induced Ischemia, Depression and Residency, Patient Outcomes for Part Time Hospitalists | 25 Nov 2021 | 00:59:07 | |
Somehow we got through 7 articles today, and none of them are about COVID-19! https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Race and Estimated GFR, Bleeding Risk in Oral Anticoagulation after First VTE, HEP-COVID trial, High Dose Dexamethasone for COVID-19 | 28 Oct 2021 | 00:50:33 | |
Today we talk about the effect of eliminating the race coefficient from the estimated GFR calculators, the risk of bleeding from anticoagulation after first unprovoked VTE, another trial looking at therapeutic anticoagulation in COVID-19, and whether 12 mg of dexamethasone is better than 6 mg for severe COVID-19 infections. https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Empagliflozin for HFpEF, Antibiotic Duration for UTIs in Men, Targeted Temperature after Cardiac Arrest, Normal Saline vs Balanced Solution in ICU Patients, Baricitinib and Therapeutic Anticoagulation for Hospitalized COVID-19 Patients | 30 Sep 2021 | 01:01:52 | |
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| Antibiotic Duration for Prosthetic Joint Infections, Colorectal Cancer Screening Guidelines, Hospital Observation after ACS Ruled Out in ED, Morning Discharges, Personalized Steroid Regimen for COPD Exacerbation | 03 Jun 2021 | 01:03:27 | |
Today is our season 2 finale, and we have a master class on prosthetic joint infections from Dr. Laura Certain. Is 6 weeks as good as 12 weeks for prevent recurrent infections? How does the surgeon decide what kind of surgery to do? Should we use oral or IV antibiotics? When should you use rifampin?? Dr. Certain answers all these questions and more. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Antibiotic Delay Intervals and Hospital Mortality for Patients with Suspected Sepsis, Guidelines for High Flow Nasal Oxygen and Point of Care Ultrasound for Acute Dyspnea, Screening for Atrial Fibrillation in Older Patients | 13 May 2021 | 00:45:22 | |
How long can you delay antibiotics in patients with suspected sepsis before the risk of hospital mortality increases? What proportion of patients with suspected sepsis end up having actual sepsis? Dr. Devin Horton joins us to review a paper in Critical Care Medicine that tries to answer these questions. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Hospital at Home for Geriatric Patients, RAAS Inhibition and Pulmonary Hypertension, Vaccine Induced Immune Thrombotic Thrombocytopenia (VITT) | 28 Apr 2021 | 00:59:28 | |
Today we have special guest Dr. Natalie Como to talk about Hospital at Home and what it's like to practice hospital medicine at a rural critical access hospital. We also look at a retrospective paper on ACE/ARBs in veterans with pulmonary hypertension and talk about vaccine-induced immune thrombotic thrombocytopenia (VITT). Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Three Days of Antibiotics for Pneumonia, IV Contrast and Kidney Function, DOACs for Valvular Atrial Fibrillation | 08 Apr 2021 | 00:51:13 | |
Today we are joined by heavy hitter Dr. Brian Locke to talk about the new paper on 3 vs 8 days of antibiotics for pneumonia, a clever new paper looking at whether there is any association between IV contrast and kidney function, and a new retrospective study on DOAC use for valvular atrial fibrillation. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Weekly Semaglutide for Weight Loss (STEP 1, 2 and 3 Trials), 4PEPS Rule for Pulmonary Embolism, Nafcillin vs Cefazolin for Epidural Abscess, Ferritin/Procalcitonin Ratio for COVID19, Intermediate Thromboprophylaxis for COVID19 | 24 Mar 2021 | 00:50:49 | |
Today we are doing double duty: podcasting and parenting. Fortunately our babies were well-behaved. We talk about three trials for semaglutide and weight loss and a new 4 level pre-test probability rule for diagnosing PE. We also talk about a retrospective study of cefazolin vs nafcillin for epidural abscess, a ferritin/procalcitonin ratio for differentiating bacterial from COVID pneumonia, and a new randomized controlled trial of intermediate thromboprophylaxis for ICU patients with COVID19. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Albumin Infusion for Decompensated Cirrhosis (ATTIRE trial), Terlipressin for Type 1 Hepatorenal Syndrome (CONFIRM trial) | 11 Mar 2021 | 00:39:00 | |
Today has a nice liver disease theme. Does targeting a serum albumin above 3 g/dL reduce death, infections and kidney failure in patients with decompensated cirrhosis? Does terlipressin work in hepatorenal syndrome? Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| IL-6 Receptor Antagonists Reduce Mortality in Critically Ill COVID-19 Patients (REMAP-CAP, RECOVERY), Convalescent Plasma Fails to Improve Mortality | 04 Mar 2021 | 00:42:34 | |
Today I am joined by Infectious Disease expert Dr. Emily Spivak to talk about the latest batch of tocilizumab trials for COVID-19 and a meta-analysis of all the convalescent plasma trials. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| 7 vs 14 Days of Antibiotics for Bacteremia, Factor XI Inhibition for Atrial Fibrillation, ACEi or ARB Before Elective Surgery, GLP-1 Agonist for HFpEF and Obesity | 07 Feb 2025 | 01:06:04 | |
We're back, after a brief hiatus! Today we talk about duration of therapy for bacteremia, Factor XI inhibition for atrial fibrillation, whether to stop ACEi or ARB before elective surgery, and whether GLP-1 agonists are beneficial in heart failure with preserved ejection fraction. Go to minute 7:30 to skip the banter. 7 vs 14 Days of Antibiotics for Bacteremia (BALANCE) Abelacimab vs Rivaroxaban for Atrial Fibrillation (AZALEA-TIMI-71) Asenduxian vs Apixaban for Atrial Fibrillation (OCEANIC-AF) ACEi or ARB Discontinuation Before Surgery (STOP or NOT) Tirzepatide for HFpEF and Obesity (SUMMIT) Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Gender-Based Discrimination and Harassment Among Hospitalists, Educational Resource Utilization in Internal Medicine Residents, Transfusion Thresholds for ACS, DOACs for VTE prevention in CKD | 18 Feb 2021 | 01:05:56 | |
Today we have special guests Dr. Emily Signor and Dr. Amanda Breviu, two hospitalists, to talk about a survey published in JHM on gender-based discrimination among hospitalists. We also discuss a survey published in JGIM on educational resources used by internal medicine residents. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Early Ablation vs Medications for Atrial Fibrillation (STOP-AF First, EARLY-AF), ACEi and ARBs in COVID-19, IV vs Oral Antibiotics for Appendicitis, Rifaximin after TIPS, Low vs High Oxygen Targets | 04 Feb 2021 | 00:57:17 | |
Today we have a special guest, Dr. Jared Bunch, an international expert in atrial fibrillation and ablation, to talk about the state of atrial fibrillation and which patients benefit from early catheter ablation based on two new trials published last week in the NEJM. We also talk about whether you should stop ACEi or ARBs in patients admitted with COVID-19, whether oral antibiotics are adequate for uncomplicated appendicitis, and whether you should target a high (90 mmHg) or low (60 mmHg) paO2 in patients with respiratory failure. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Inhaled Treprostinil for Pulmonary Hypertension due to Interstitial Lung Disease, Omecamtiv Mecarbil for Systolic Heart Failure (HFrEF) | 20 Jan 2021 | 00:35:37 | |
Today I am joined by pulmonary hypertension and heart failure expert, Dr. John Ryan, to talk about inhaled treprostinil for pulmonary hypertension due to ILD, and a new cardiac myosin activator, omecamtiv mecarbil, for treatment of systolic heart failure. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Prevalence of Pulmonary Embolism in Acute COPD Exacerbation, Tocilizumab for COVID-19 Round 3 | 14 Jan 2021 | 00:54:48 | |
WARNING: This episode is long on banter. If you would like to skip the intro conversation and get right to the articles, skip ahead to 12:13. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Treatment of Inpatient Hypertension, Testing and Treatment of Primary Aldosteronism in Patients with Resistant Hypertension, Tocilizumab for COVID-19 Round 2 | 07 Jan 2021 | 00:35:02 | |
The president's supporters may have stormed the capitol and attempted a coup today, but the show must go on. Today I'm joined by Dr. Dani Babbel to talk about treatment of hypertension in the hospital, as well as testing for primary aldosteronism in patients with resistant hypertension. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Thrombosis and COVID-19 | 30 Dec 2020 | 00:17:09 | |
Today I do a quick review of the COVID-19 thrombosis literature from the last year to try to answer some of the following questions: Why does COVID-19 cause thrombosis? How many patients with COVID-19 develop thrombotic complications? Why do patients with COVID-19 on VTE prophylaxis still develop blood clots? Should we use intermediate dosing of anticoagulation for prophylaxis? What about full dose therapeutic anticoagulation (no!) What do the guidelines say?
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| Inappropriate Testing and Treating of Asymptomatic Bacteriuria, Baricitinib Plus Remdesivir for COVID-19 (ACTT-2), COVID-19 Vaccine, Noninvasive Respiratory Protocol for COVID-19, Iron Supplementation in Acute Heart Failure | 16 Dec 2020 | 00:47:18 | |
Today we have special guest Dr. Valerie Vaughn to talk about her new paper in Open Forum Infectious Diseases about inappropriate treatment and testing for asymptomatic bacteriuria. Then we talk about the new ACTT-2 trial results of baricitinib plus remdesivir for COVID-19. We also review the BioNTech/Pfizer vaccine safety and efficacy results, a noninvasive respiratory protocol to reduce intubations in COVID-19, and iron deficiency in acute heart failure. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Patient Outcomes in Resident, APC and Solo Hospitalist Teams, Rapid Conversion to Oral Antibiotics in Pneumonia, SOLIDARITY trial for COVID-19 | 10 Dec 2020 | 00:52:05 | |
Today we have special guests Dr. Claire Ciarkowski and Dr. Stacy Johnson to talk about two recent papers they published, as well as the new SOLIDARITY trial results. Are patient outcomes the same for resident, APC and solo hospitalist teams? How do you get doctors to switch to oral antibiotics faster when treating pneumonia? And with the new SOLIDARITY results showing no benefits for remdesivir, should we still be using it for COVID-19? Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Danish Mask Study, Rivaroxaban for Atrial Fibrillation and Bioprosthetic Mitral Valve, Convalescent Plasma Fails, Semaglutide in NASH, Once Weekly Insulin, Statin Nocebo Effect | 03 Dec 2020 | 00:38:11 | |
We're back with our second episode of the new season. Dr. Rupp is sporting a new mustache, and we discuss the mysterious monolith discovered in the Utah desert. If you want to skip the banter, go to 6:56. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Remdesivir Redux, Tocilizumab Fails, Bamlanivimab gets EUA and mRNA Vaccines for COVID-19 | 19 Nov 2020 | 00:39:11 | |
We're back after a prolonged hiatus, ready to break down the latest and greatest in the medical literature. Today's episode will get you caught up on the newest treatments for COVID-19. We promise to talk about something else next time :) Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Anticoagulation in AF with Cirrhosis, Trends in Anticoagulation for Acute PE, Beta Blockers for Acute MI with Normal EF, Finerenone for HFpEF, Continuous vs Intermittent Infusion for Antibiotics, Cefepime vs Piperacillin-Tazobactam for Sepsis | 23 Sep 2024 | 01:05:23 | |
It's been a long time, but we are back! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Caring for COVID-19 Patients in the Navajo Nation | 16 Jul 2020 | 00:34:43 | |
Today we are joined by a special guest, Dr. Lawanda Jim, chief of internal medicine at Northern Navajo Medical Center, to talk about what it's been like taking care of patients during the pandemic in Shiprock, NM. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Dexamethasone Reduces Mortality in COVID-19: The RECOVERY Trial | 10 Jul 2020 | 00:30:29 | |
Today we're back with a spirited discussion of a pre-print publication for the dexamethasone arm of the RECOVERY trial. Should hospitalized COVID19 patients receive dexamethasone? Take a listen and decide for yourself. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Remdesivir Shortens Time to Recovery in COVID19 (ACTT-1), CRP-Guided Antibiotics for Gram Negative Bacteremia, NT-pro-BNP in Syncope | 05 Jun 2020 | 00:36:26 | |
We're back with another episode. We cover the latest highlights in COVID, including the exciting new results on remdesivir from the ACTT-1 trial. We also talk about whether you can use CRP to guide duration of antibiotic therapy in patients with gram negative bacteremia, and whether NT-pro-BNP can help you risk-stratify patients with syncope. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Triple Antiviral Therapy for COVID-19, Remdesivir for Severe COVID-19, Convalescent Plasma, Hydroxychloroquine and Azithromycin in New York | 20 May 2020 | 00:43:54 | |
We're back with some of the latest updates on COVID-19! Are hydroxychloroquine or azithromycin associated with increased risk of mortality or cardiac arrest? Does triple combination antiviral therapy shorten time to a negative viral swab? Does remdesivir shorten time to clinical improvement? Should we be giving patients convalescent plasma? If you were the patient with severe COVID-19, which therapies would you want? Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| COVID-19 in New York City, Lopinavir-Ritonavir in Severe COVID-19, The French Hydroxychloroquine Study, Chinese Hydroxychloroquine RCT, VA Hydroxychloroquine Study, Compassionate Use of Remdesivir | 30 Apr 2020 | 00:40:13 | |
It's been a while! We took a short hiatus while our lives were upended by the pandemic. But we couldn't stay away forever. Today we review some of the big trials published in the last month on Covid-19. We look at the large case series on New York patients published in JAMA, three hydroxychloroquine studies, the lopinavir-ritonavir study and the compassionate use of remdesivir study. Buckle up! Lopinavir-Ritonavir in Severe COVID-19
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| COVID-19 Update, Gabapentin for Alcohol Use Disorder, Apixaban versus Rivaroxaban for Atrial Fibrillation | 18 Mar 2020 | 00:29:59 | |
Seems like a lot has happened in just one week! The whole world is different. Today we talk about some of the most recent articles published about the ongoing COVID-19 pandemic. We also discuss whether gabapentin can be used to treat people with alcohol use disorder, and whether apixaban is better than rivaroxaban for preventing strokes in people with atrial fibrillation. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Long Acting Injectable Therapy for HIV and Pregnenolone for Chronic Low Back Pain | 10 Mar 2020 | 00:25:12 | |
Austin finally returns to the podcast with harrowing tales of almost being eaten by a wolf. Today we discuss a new NEJM paper about long acting injectable therapy for HIV and a new JAMA paper about pregnenolone, a neurosteroid that may help treat the scourge of primary care: chronic low back pain. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| COVID-19, PPI Use and MDRO Colonization, Hospitalist Care of ED Boarders | 04 Mar 2020 | 00:32:55 | |
Today we had Dr. Dani Babbel back on the show to talk about the latest COVID-19 updates, whether gastric acid suppression increases your risk of MDRO colonization, and how to improve care to patients boarding in the emergency department. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Empirical Anti-MRSA vs Standard Antibiotic Therapy in Pneumonia, High Consulting Hospitalists, Medicare for All | 25 Feb 2020 | 00:31:51 | |
Today we had the pleasure of talking to Dr. Barbara Jones, first author on a new paper in JAMA IM about the outcomes in veterans treated with empirical anti-MRSA therapy vs standard therapy. She gives us a master class in propensity weighted analysis and instrumental variable analysis. We also look at whether outcomes are different in patients who are cared for by hospitalists who call more consults than their colleagues, and how much money we could save with a single payer system in the United States. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Plasma Exchange and Glucocorticoids for ANCA-Vasculitis and Dexamethasone for ARDS, aka the PLEX and DEX episode | 19 Feb 2020 | 00:31:06 | |
Today we have the venerable EBM guru Dr. Brian Locke on the show to talk PLEX and DEX. Does plasma exchange for ANCA-vasculitis really work? Do steroids make any difference in patients with ARDS? Also, have you ever wondered which Hogwarts house your medical specialty belongs to? Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Metformin and Long COVID, Central Lines and Thrombocytopenia, DOACs vs LMWH in Cancer Associated Thrombosis, Early vs Late Anticoagulation after Stroke with Atrial Fibrillation | 27 Jun 2023 | 00:59:11 | |
Today we are joined by Dr. Brian Locke, recently graduated pulmonary-critical care fellow, who takes us on a journey of avoiding statistical fallacies. Does metformin reduce the likelihood of long COVID? Should we give platelet transfusions to thrombocytopenic patients before central line placement? Did the CANVAS trial change practice in cancer associated thrombosis? Should patients with a stroke due to atrial fibrillation start oral anticoagulation earlier or later? We discuss all these questions on more on today's episode. Check it out! https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Aspirin for VTE Prophylaxis after THA or TKA, Fluid Management for Sepsis in Patients with ESRD, Cirrhosis and CHF | 11 Feb 2020 | 00:29:09 | |
Today we are joined by the man, the myth, and the legend, Dr. Stacy Johnson, to talk about a new meta-analysis of using aspirin for DVT prophylaxis after a total hip or knee replacement. We also review a new retrospective cohort study from Cleveland Clinic on whether it's safe to give the recommended 30 ml/kg fluid bolus to patients with sepsis who also have CHF, cirrhosis or ESRD. Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| CT Screening for Lung Cancer, Conservative vs Interventional Treatment for Spontaneous Pneumothorax | 04 Feb 2020 | 00:28:57 | |
Today we are joined by the very smart Dr. Jason Carr, a pulmonary/critical care fellow, to talk about two big papers from the wonderful world of lungs. Does CT screening for lung cancer save lives? Do you have to put a chest tube in every patient with a spontaneous pneumothorax? Check it out! Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Novel Coronavirus, High Sensitivity Troponins, Hydroxyethyl Starch for Abdominal Surgery and Testosterone Therapy in Men | 28 Jan 2020 | 00:27:43 | |
It's our tenth episode! Thanks for getting us this far. Today we discuss the new coronavirus outbreak, what to do with high sensitivity troponins, whether hydroxyethyl starch should be used in abdominal surgery (spoiler alert: it shouldn't) and the appropriate use of testosterone therapy. Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||
| Factor XIa Inhibition for VTE Prophylaxis, Physician Time Using EHR in Outpatient Encounters, Vitamin C and Thiamine for Septic Shock | 22 Jan 2020 | 00:30:41 | |
Today we are joined by the wonderful Dr. Emily Signor to talk about new therapeutic approaches to DVT prophylaxis, how much time physicians spend using the EHR in clinic, and whether that Vitamin C cocktail works for septic shock. Check it out! Physician Time Spent Using the EHR During Outpatient Encounters Vitamin C, Thiamine and Hydrocortisone for Septic Shock Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R | |||