Back

Explore every episode of the podcast JNNP Podcast

Dive into the complete episode list for JNNP Podcast. Each episode is cataloged with detailed descriptions, making it easy to find and explore specific topics. Keep track of all episodes from your favorite podcast and never miss a moment of insightful content.

Rows per page:

1–50 of 181

TitlePub. DateDuration
Distinguishing autoimmune nodopathies from CIDP, with Dr. Ruth Huizinga and Dr. Maarten Titulaer15 Jul 202400:38:57

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) can be difficult to distinguish from autoimmune nodopathy. In this podcast, Dr. Saima Chaudhry (1) is joined from the Netherlands by Dr. Ruth Huizinga (2) and Dr. Maarten Titulaer (3), to discuss their article, "Clinical relevance of distinguishing autoimmune nodopathies from CIDP: longitudinal assessment in a large cohort". They start with explaining what an autoimmune nodopathy really is, patient features to look out for, and the typical testing process for identifying CIDP.

(1) Warren Alpert Medical School, Brown University, Rhode Island, USA

(2) Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

(3) Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

Please subscribe to the show on Apple PodcastsSpotify or find it on your platform of choice. Your feedback and reviews are very appreciated.

Follow JNNP on twitter: @JNNP_BMJ

 

Nutritional peripheral neuropathies, with Dr. Alexander Rossor17 Apr 202400:39:42

The cause of a nutritional neuropathy may not always be obvious when first examining a patient. Restrictive diets with roots in religious practices or personal preferences will be less familiar to neurologists than issues involving bariatric surgery or diseases of malabsorption, and can present as being not overtly malnourished. A recent review in JNNP details links between B-vitamin deficiencies and peripheral neuropathy, and discusses historical trends in the occurrence of nutritional neuropathies. The review's last author, Dr. Alexander Rossor (1), joins host Dr. Saima Chaudhry (2) to talk through how to approach this diagnosis.

 

Read the paper here: "Nutritional peripheral neuropathies"

 

(1) UCL Queen Square Institute of Neurology, London, UK (2) Warren Alpert Medical School, Brown University, Rhode Island, USA

Please subscribe to the show on Apple PodcastsSpotify or find it on your platform of choice. Your feedback and reviews are very appreciated.

Follow JNNP on twitter: @JNNP_BMJ

The impact of traumatic brain injury on neurocognitive outcomes in children31 Aug 202100:09:54

Mark Goh and Shu-Ling Chong, Duke-NUS Medical School and KK Women's and Children's Hospital, Singapore joins editor Colin Mahoney to discuss their systematic review and meta-analysis spanning 6000 articles dealing with neurocognitive outcomes following traumatic brain injury (TBI) in children. They highlight how dose of TBI impacts executive function and memory with potentially long term impacts. https://jnnp.bmj.com/content/92/8/847

BNPA 2014: Joint hypermobilty and autonomic hyperactivity17 Sep 201400:05:13
Chis Butler, MRC Clinician Scientist and Honorary Consultant Neurologist at the University of Oxford, talks to Jessica Eccles, MRC Clinical Research Training Fellow, Brighton and Sussex Medical School, about her work into joint hypermobilty and autonomic hyperactivity, and their relevance to neurodevelopmental disorders. Read the abstract: http://jnnp.bmj.com/content/85/8/e3.40.abstract

This podcast was recorded at the 2014 British NeuroPsychiatry Association AGM.

BNPA 2014: Post-Ictal psychosis17 Sep 201400:05:10
Hugh Rickards, consultant in Neuropsychiatry and honorary reader in Neuropsychiatry at Birmingham University, talks to Georgy Pius, ST6 Trainee, North West Deanery, about his case-control study examining post-ictal psychosis. Read the abstract: http://jnnp.bmj.com/content/85/8/e3.39.abstract

This podcast was recorded at the 2014 British NeuroPsychiatry Association AGM.

BNPA 2014: TREM2 variants and risk of dementia17 Sep 201400:04:48
Chris Butler, MRC Clinician Scientist and Honorary Consultant Neurologist at the University of Oxford, talks to Catherine Slattery, Clinical Research Associate, Institute of Neurology, about her work looking at TREM2 and associated risk of dementia. Read the abstract: http://goo.gl/SkJVXr

This podcast was recorded at the 2014 British NeuroPsychiatry Association AGM.

Neurosurgical procedures for psychiatric illness17 Sep 201400:17:53
This month, how to safely and ethically carry out stereotactic surgery for psychiatric illness. Bart Nuttin, Department of Neurosurgery, University of Leuven, has put together pragmatic guidelines, with the input of international psychiatric and neurosurgical societies.Here he gives us an overview.

Read the guidelines in full: http://jnnp.bmj.com/content/85/9/1003.full

Can stress trigger Parkinson’s? And new criteria for frontotemporal dementia syndromes.05 Aug 201400:36:54

Does emotional stress trigger Parkinson's disease? Andrew Lees, Reta Lila Weston Institute of Neurological Studies, talks us through the evidence so far.

And Glenda Halliday, Neuroscience Research Australia, and colleagues, have examined the clinical and pathological diagnostic implications of new criteria for frontotemporal dementia syndromes. She discusses the highlights.

Read both the papers, for free:

New criteria for frontotemporal dementia syndromes: clinical and pathological diagnostic implications http://goo.gl/87At72

Can stress trigger Parkinson's disease? http://goo.gl/bS8igN

Listen to the PN podcast reviewing Michael J Fox's memoir, Lucky Man http://goo.gl/1XCpDP

HIV and multiple sclerosis: beginning to unravel a mystery02 Jul 201400:13:27

Julian Gold, professor in the department of neuroscience and trauma, Queen Mary, University of London, and senior staff specialist, Albion Centre, Prince of Wales Hospital, Sydney, discusses his paper which investigates whether or not HIV protects against developing MS.

Read the paper, for free:

HIV and lower risk of multiple sclerosis: beginning to unravel a mystery using a record-linked database study http://goo.gl/j0G3SR

BNPA 2014: Neuropsychiatry of social knowledge and moral motivation24 Jun 201400:11:08

JNNP editor Alan Carson asks Roland Zahn, senior clinical lecturer, King's College London, about the neuroanatomy of moral behaviour, particularly his work into the neural mechanism of moral emotion in depression.

This podcast was recorded at the 2014 British NeuroPsychiatry Association AGM.

DBS in essential tremor, and genetic counselling for ALS22 May 201400:22:34

This month, genetic counselling for amyotrophic lateral sclerosis (ALS). Adriano Chiò, Turin ALS Expert Center, ‘Rita Levi Montalcini’ University of Turin, tells us what it can and can't do, who should have it, and how to go about it.

And deep brain stimulation for essential tremor. Joseph Jankovic, Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine, explains what his study on long-term outcomes reveals.

Read the papers:

Genetic counselling in ALS: facts, uncertainties and clinical suggestions http://goo.gl/bYaqtQ

The safety and efficacy of thalamic deep brain stimulation in essential tremor: 10 years and beyond http://goo.gl/OhCsIh

Mortality and morbidity 15 years after hospital admission with mild head injury30 Apr 201400:14:18

Head injury is very common, and we know those admitted to hospital with a severe head injury have a high mortality rate in the proceeding year. However less is known about later mortality, and even less about late survival after mild head injury, which accounts for 95% of all head injuries.

Tom McMillan, Institute of Health and Wellbeing, MVLS, University of Glasgow, and colleagues, have followed up patients 15 years after admission with a mild head injury, and recently published the results in JNNP.

In this podcast, Alan Carson, JNNP associate editor, asks him what they found.

Read the full paper:

Mortality and morbidity 15 years after hospital admission with mild head injury: a prospective case-controlled population study http://goo.gl/9aTU4Z

Informed decision making in MS, and the striatum in neurodegeneration04 Apr 201400:29:38

What's the role of the striatum, in changes in cognition and behaviour in neurodegeneration? Michael Hornberger, University of Cambridge, explains why it may be more pivotal than we currently think.

And how best to support patients just diagnosed with multiple sclerosis, who are facing difficult decisions around their treatment? Sascha Köpke, University of Lübeck, discusses the results of his trial comparing two programmes.

Read the papers, for free:

Beyond and below the cortex: the contribution of striatal dysfunction to cognition and behaviour in neurodegeneration http://goo.gl/IZJi2o

Evidence-based patient information programme in early multiple sclerosis: a randomised controlled trial http://goo.gl/nQdJ15

Cerebral Microbleeds: from depiction to interpretation05 Jul 202100:10:23
Cerebral Microbleeds are increasingly recognised due to increased availability of neuroimaging and are known to be associated with increased risk of stroke, in particular intracerebral haemorrhage. In this podcast Dr Laurent Puy joins editor Colin Mahoney to discuss their histopathology, epidemiology and impact on clinical decision making in a state-of-the-art review published in June's JNNP.

https://jnnp.bmj.com/content/92/6/598

BNPA special: Autoimmune encephalitis14 Mar 201400:10:59

Angela Vincent, emeritus professor of neuroimmunology at the University of Oxford, gives Adam Zeman, professor of cognitive and behavioural neurology, University of Exeter, an overview of autoimmune disorders of the central nervous system.

This podcast is one of several recorded with the British Neuropsychiatry Association, more of which will be published over the next few months. For all the podcasts in this series, see: soundcloud.com/tags/bnpa%202014

BNPA special: The prospects of a vaccine for Alzheimer’s disease13 Mar 201400:10:08

Adam Zeman, professor of cognitive and behavioural neurology, University of Exeter, asks James Nicoll, professor of neuropathology, University of Southampton, about the progress being made in preventative treatments for Alzheimer's.

For more on early treatment for Alzheimer's, watch Nick Fox's talk on presymptomatic treatment for the dementias on JNNP's YouTube channel: http://goo.gl/95sVXB

Both this podcast and the Professor Fox's talk were recorded with with the British Neuropsychiatry Association. More BNPA podcasts will be published over the next few months, for all those in the series see: soundcloud.com/tags/bnpa%202014

An unusual variant of Guillain–Barré syndrome, and dopamine dysregulation syndrome04 Mar 201400:25:57

This month, an unusual variant of Guillain Barre syndrome - the pharyngeal cervical brachial variant. Benjamin Wakeley, a consultant neurologist at the Gloucester Hospitals NHS Foundation trust talks through what clinicians need to know.

Also, a look at an uncommon but difficult to resolve complication of Parkinson’s disease therapy - that of dopamine dysregulation syndrome. Robert Cilia, from the Parkinson Institute in Milan, discusses his paper examining the characterisation, management and long-term outcome.

If you found that useful you may want to listen to our accompanying podcast on impulse control disorder in Parkinson’s disease, produced with the British Neuropsychiatry association. David Okai, a consultant in psychological medicine in Oxford discusses assessing and managing the disorder. Listen here: goo.gl/gEsUUA

Read the articles:

Dopamine dysregulation syndrome in Parkinson's disease: from clinical and neuropsychological characterisation to management and long-term outcome goo.gl/AEH3vr

Pharyngeal-cervical-brachial variant of Guillain–Barré syndrome goo.gl/HFIqla

BNPA special: Impulse control disorder in Parkinson’s03 Mar 201400:08:41

Kieran O'Driscoll, consultant neuropsychiatrist in Liverpool, talks to David Okai, a consultant in psychological medicine in Oxford and researcher at King's College London, discusses assessing and managing impulse control disorder in Parkinson's.

This podcast is one of several recorded with the British Neuropsychiatry Association, more of which will be published over the next few months. For all the podcasts in this series, see: soundcloud.com/tags/bnpa%202014

See also:

Impulse control disorder in patients with Parkinson's disease under dopamine agonist therapy: a multicentre study goo.gl/45jOZm

Trial of CBT for impulse control behaviors affecting Parkinson patients and their caregivers goo.gl/6AB4QB

Impulse control disorders and dopamine dysregulation in Parkinson's disease: a broader conceptual framework goo.gl/nX5P6S

Diagnosing and treating functional symptoms10 Jan 201400:27:59

February's JNNP is a neuropsychiatry special issue, with papers on a broad range of disorders which lie between neurology and psychiatry. Associate editor Alan Carson discusses the contents, and the thinking behind the edition.

To accompany the issue, JNNP and the Association of British Neurologists convened a roundtable of experts to discuss, and advise on, diagnosing and treating functional symptoms. Dr Carson takes part in this, along with:

Kailash Bhatia, professor of neurology, Institute of Neurology

Mark Edwards, neurologist at the National Hospital for Neurology and Neurosurgery

Jon Stone, neurologist, University of Edinburgh, Western General Hospital

This podcast is one of a series produced in collaboration with the Association of British Neurologists. You can find all the podcasts in the series here: soundcloud.com/tags/abn%202013

Solving the case, making the diagnosis: Neurology and detective writing09 Jan 201400:19:44
When searching for clues to reach a diagnosis, neurologists often empathise with the detective who is trying to solve a case, write Peter Kempster and Andrew Lees in JNNP sister journal Practical Neurology bit.ly/1dqReQq. In this podcast, journal editor Phil Smith and Andrew Lees, director of the Queen Square Brain Bank in London, discuss how neurologists draw upon detective skills. They also talk about neurologists who have turned these skills to crime fiction writing, and the use of narrative in clinical case histories. The expert witnesses called upon are: - Oliver Sacks, best selling author and professor of neurology at NYU School of Medicine - Peter Gautier Smith, now retired from consulting at Queen Square and author of 31 detective novels - Chris Goetz, who worked at Rush University Medical Centre with Harold Klawans, crime fiction writer and authority on Parkinson’s disease Listen to the full interviews here: Andrew Lees bit.ly/1cPaoxM Peter Gautier-Smith bit.ly/1d5HhKj Harold Klawans bit.ly/19cXR

Oliver Sacks bit.ly/1hBsbgz

Radiation for brain metastases, and the genetics of ischaemic stroke26 Nov 201300:27:14

This month, whole brain radiation vs radiosurgery for cerebral metastases. Does the former cause significantly more cognitive defects, and are any blanket, mopping up effects worth it? Clark Chen, vice chairman of neurosurgery, University of California San Diego, talks us through his review.

And a clinical guide to the genetics of ischaemic stroke, from Pankaj Sharma, Imperial College Cerebrovascular Research Unit.

Read the full papers:

Review: Genetics of ischaemic stroke bit.ly/1aptzNl

Neurocognitive assessment following whole brain radiation therapy and radiosurgery for patients with cerebral metastases http://bit.ly/1aptIjQ

Education special: Headache26 Nov 201300:19:44

Callum Duncan, neurologist at Aberdeen Royal Infirmary, convenes a round table of experts to discuss advances in headache, particularly the pathophysiological understanding of cluster headache, managing cluster headache and migraine, and new onset chronic daily headache.

Taking part are:

Phillip Holland, postdoctoral researcher, Centre for Cognitive and Neural Systems, University of Edinburgh

Manjit Matharu, clinical lead of the Headache Group at The National Hospital for Neurology and Neurosurgery, London

Alok Tyagi, neurologist, Southern General Hospital, Glasgow

This podcast is one of a series produced in collaboration with the Association of British Neurologists, of which there will be more to come over the next few months. You can find all the podcasts in the series here: soundcloud.com/tags/abn%202013

Aggressive MS, and disappointment following deep brain stimulation for Parkinson’s25 Oct 201300:21:05

This month, getting a handle on aggressive multiple sclerosis. Suresh Menon and Helen Tremlett, both from the Department of Medicine, University of British Columbia, talk us through their recent step towards a definition of the disease.

And Parkinson's patients who are disappointed after deep brain stimulation, despite gaining motor benefits and quality of life improvements. Catherine Lewis and Franziska Maier, both from the Department of Neurology, University of Cologne, explain how to predict who may end up feeling negative about the procedure, and how to support them.

Read the papers:

Characterising aggressive multiple sclerosis bit.ly/168RLWo

Patients’ expectations of deep brain stimulation, and subjective perceived outcome related to clinical measures in Parkinson's disease: a mixed-method approach bit.ly/Hlup68

Vitamin D, sunlight, and MS15 Oct 201300:10:40

October's JNNP takes another step towards demystifying the relationship between sunlight, vitamin D, and MS, featuring a paper which reveals sun exposure may have direct effects on neurodegeneration independently of the vitamin.

Murali Ramanathan, co-author of the study and professor of pharmaceutical sciences and neurology at the State University of New York at Buffalo, talks us through the research.

Read the full paper, for free, here: bit.ly/171jo6N

Motor functional neurological disease, a decade of progress25 Jun 202100:09:52
Over the last ten years, huge progress has been made in the common but often poorly understood condition of motor Functional Neurological Disorder (mFND). In this podcast, Dr W. Curt La France, Jr., Professor of Neurology and Psychiatry, Brown University, USA, joins editor Colin Mahoney to discuss diagnosis, insights on disease mechanisms, and emerging therapeutic approaches. They also highlight the stigma associated with mFND and ways to improve outcomes for patients.

Read the paper on the JNNP website and the journal's June issue: https://jnnp.bmj.com/content/92/6/668

Education special: Neurogenetics update15 Oct 201300:09:39

Ralph Gregory, secretary for the Association of British Neurologists and consultant neurologist in Dorset, gets an update on neurogenetics research and implications for practice from Nick Wood, professor of clinical neurogenetics, Institute of Neurology.

This podcast is one of a series produced in collaboration with the Association of British Neurologists, of which there will be more to come over the next few months. You can find all the podcasts in the series here: soundcloud.com/tags/abn%202013

Diagnosing and treating neuromyelitis optica19 Aug 201300:21:29

Neuromyelitis optica (NMO) is an autoimmune inflammatory disorder with predilection for the optic nerves and spinal cord. Many recent advances, in particular, the discovery of NMO-IgG, an NMO-specific autoantibody, have furthered our understanding of the condition.

Anu Jacob, consultant neurologist, The Walton Centre for Neurology and Neurosurgery, Liverpool, summarises what clinicians need to know in terms of diagnosing and treating NMO and its spectrum disorders.

Read the full review, for free, here: http://goo.gl/fidlGL

Diagnosing the dementias23 Jul 201300:27:58

This month, we get an update on the latest in clinically diagnosing the dementias, with a roundtable of experts convened by the Association of British Neurologists.

Taking part are John Greene, Southern General Hospital, Glasgow, Chris Butler, Department of Clinical Neurology, University of Oxford, Nick Fox, Dementia Research Centre, UCL Institute of Neurology, and Huw Morris, Cardiff University School of Medicine.

And using theory of mind deficits as an early marker of frontotemproal dementia. Matteo Pardini, Department of Neurosciences, University of Genoa, talks us through his research.

See also:

Isolated theory of mind deficits and risk for frontotemporal dementia: a longitudinal pilot study http://bit.ly/19figvN

Anti-GQ1b antibody syndrome, and ALS and language deficits05 Jul 201300:27:39

We know that ALS is associated with executive dysfunction, but what about language deficits? Steven Wing, specialist neurology registrar at Addenbrooke’s Hospital, Cambridge, talks to Laura Goldstein, professor of Clinical Neuropsychology at the Institute of Psychiatry, about her recent paper investigating this.

And anti-GQ1b antibody syndrome, or Bickerstaff brainstem encephalitis and Fisher syndrome. Editor Matthew Kiernan talks to Nobuhiro Yuki, Department of Medicine, National University of Singapore, about how the syndrome was first identified, and what we currently understand about it.

See also:

Is language impairment more common than executive dysfunction in amyotrophic lateral sclerosis? http://bit.ly/1a6cRIz

Bickerstaff brainstem encephalitis and Fisher syndrome: anti-GQ1b antibody syndrome http://bit.ly/1aJrTmK

Striatal cell transplants for Huntington’s disease: where are we now?05 Jul 201300:20:28

In Huntington’s disease the striatum takes a big hit early. This has prompted trials of foetal stratal transplantation, in the hope that this may provide some relief to patients.

Stevan Wing, specialist neurology registrar at Addenbrooke’s Hospital, and researcher, University of Cambridge, speaks to Professor Roger Barker, John van Geest Centre for Brain Repair, University of Cambridge, about his experience of leading a transplant trial with the NEST-UK consortium.

See also:

The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington’s disease http://jnnp.bmj.com/content/84/6/657.long

Education special: MS update11 Jun 201300:14:40

Ralph Gregory, secretary for the Association of British Neurologists and consultant neurologist in Dorset, gets an update on multiple sclerosis research and implications for practice from Neil Robertson, professor of neurology, Cardiff University.

They discuss new therapeutics BG-12 and alemtuzumab, the understanding of treatment risks, prognosis, prevalence and incidence, and MS and pregnancy.

This podcast is one of a series produced in collaboration with the Association of British Neurologists, of which there will be more to come over the next few months. You can find all the podcasts in the series here soundcloud.com/tags/abn%202013.

Education special: Peripheral nerve disease update11 Jun 201300:20:02

Ralph Gregory, secretary for the Association of British Neurologists and consultant neurologist in Dorset, gets an update on peripheral nerve disease research and practice from James Overell, consultant neurologist, Institute of Neurological Sciences, Glasgow.

They discuss treatment for CIDP, differences in neuropathy prevention and management in type 1 and type 2 diabetes, chronic inflammatory neuropathies, and hereditary motor sensory neuropathies.

This podcast is one of a series produced in collaboration with the Association of British Neurologists, of which there will be more to come over the next few months. You can find all the podcasts in the series here https://soundcloud.com/tags/abn%202013.

Stem cells in neurology, and enlarged perivascular spaces and intracerebral haemorrhage11 Jun 201300:33:57

Where are we with stem cell treatments for stroke and Parkinson’s disease? At the Association of British Neurologists’ recent annual meeting in Glasgow, Neil Scolding, director of the Bristol Institute of Clinical Neurosciences, spoke to Keith Muir, Institute of Neuroscience and Psychology, Univeristy of Glasgow, and Roger Barker, John van Geest Centre for Brain Repair, University of Cambridge, about current research, and the expensive, unproven treatments already on the market.

And using enlarged perivascular spaces to identify arteriopathy in intracerabral haemorrhage. Nick Ward, JNNP associate editor, asks David Werring, reader in neurology, UCL Institute of Neurology, what his MRI study reveals.

See also:

Enlarged perivascular spaces as a marker of underlying arteriopathy in intracerebral haemorrhage: a multicentre MRI cohort study http://bit.ly/12iZWie

Striatal cell transplants for Huntington’s disease: where are we now? http://bit.ly/18InWwa

Parkinson’s disease subtypes: lost in translation?01 May 201300:12:51

This month Connie Marras, assistant professor of neurology, University of Toronto, talks us through her review of Parkinson’s disease subtypes.

What definitions do we have so far, what could they tell us about the condition, and how can we get them incorporated into research more?

See also:

Parkinson’s disease subtypes: lost in translation? http://bit.ly/12mKxYL

The latest on stroke01 May 201300:33:49

In this special edition of the podcast, JNNP associate editor Nick Ward looks into some of the latest research into stroke.

Tracking cognitive function in those recovering from stroke in routine. Owen White, associate professor, Department of Neurology, Royal Melbourne Hospital, describes how assessing ocular motor deficits is a sensitive way of doing this. Furthermore, he describes the computerised programme he’s come up with to treat these, and why he believes doing so will lead to improvement in both sensory and motor areas.

Tatu Kauranen has also been looking into assessing cognitive function, and discusses the value of this in predicting return to work after stroke.

And Peter Rothwell explains why it’s safe and effective to treat those who’ve had an acute minor stroke as outpatients.

See also:

Stroke: mechanisms, stratification and implementation http://bit.ly/16o2YmF

Ischaemic stroke: the ocular motor system as a sensitive marker for motor and cognitive recovery http://bit.ly/ZmHFdT

Could saccadic function be a useful marker of stroke recovery? http://bit.ly/10VojTz

The severity of cognitive deficits predicts return to work after a first-ever ischaemic stroke http://bit.ly/ZVjeJg

Return to work after stroke: the role of cognitive deficits http://bit.ly/10VorCv

Feasibility, safety and cost of outpatient management of acute minor ischaemic stroke: a population-based study http://bit.ly/11VFocM

Is the outpatient management of acute minor stroke feasible and safe? http://bit.ly/11VFocM

The JNNP stroke special edition jnnp.bmj.com/content/84/3

Follow Nick Ward’s lab at UCL on Twitter http://bit.ly/18cNstj

COVID - 19 Vaccination and risk of large vessel arterial stroke03 Jun 202100:13:15
The Oxford Astra Zeneca vaccine has been associated with a rare complication of cerebral venous sinus thrombosis. Dr Colin Mahoney, JNNP Podcast Editor, interviews Prof David Werring, Professor of Clinical Neurology, UCL Queen Square Institute of Neurology, UK, about the new evidence which supports an association between vaccination and more common large vessel arterial stroke. They also discuss several cases, including treatment, and emerging biological evidence relating to causation. Read the paper "Ischaemic stroke as a presenting feature of ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopaenia", on the JNNP website: https://jnnp.bmj.com/content/early/2021/05/20/jnnp-2021-326984.

Related editorial paper: https://jnnp.bmj.com/content/early/2021/05/20/jnnp-2021-327057

Dopamine agonist withdrawal syndrome01 May 201300:10:44

The problem of those with Parkinson’s disease becoming addicted to dopamine replacement therapy is well know, but it’s also now emerging that some patients have trouble coming of dopamine agonists.

Margarita Pondal, from the Movement Disorders Centre, University of Toronto, talks us through her study looking at the prevalence of the syndrome, and the patients who are most likely to be affected.

See also:

Clinical features of dopamine agonist withdrawal syndrome in a movement disorders clinic http://bit.ly/12VwBI6

Dopamine agonist withdrawal syndrome (DAWS): perils of flicking the dopamine ‘switch’ http://bit.ly/18cN2Tu

BNPA 2013: The impact of epilepsy on cognitive function18 Feb 201300:11:13

Cognitive impairment in those with epilepsy is common. Adam Zeman, professor of cognitive and behavioural neurology, University of Exeter, ask Christoph Helmstaedter, associate professor for clinical neuropsychology, the University Clinic of Epileptology in Bonn, about the association, including the effects antiepileptic drugs can have on cognition.

Further resources:

Helmstaedter C, Witt JA. Clinical neuropsychology in epilepsy: theoretical and practical issues. Handb Clin Neurol. 2012;107:437-59.

Neuropsychology in the Care of People with Epilepsy, in the Progress in Epileptic Disorders Series. John Libbey, 2011.

Christoph Helmstaedter spoke on this topic at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: Psychedelic drugs, magical thinking and psychosis18 Feb 201300:06:39

Robin Carhart-Harris, post-doctoral researcher, Division of Brain Sciences, Imperial College London, explains his hypothesis on the shared neurobiology of psychosis, psychedelic states and spontaneous spiritual experiences to Peter Halligan, professor in the School of Psychology, Cardiff University.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: Decoding consciousness18 Feb 201300:03:48

What relevance does consciousness have for our understanding of mental conditions? Geraint Rees, deputy head of the UCL Faculty of Brain Sciences, tells Peter Halligan, professor in the School of Psychology, Cardiff University, about his work in the area.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: Epilepsy, depression and anxiety disorders18 Feb 201300:11:55

There is a complex relationship between epilepsy, depression, and anxiety disorders. Adam Zeman, professor of cognitive and behavioural neurology, University of Exeter, discusses the associations and what they mean for practice with Andres Kanner, director of the Comprehensive Epilepsy Center, University of Miami.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: Brain networks in human epilepsy18 Feb 201300:07:15

How epileptic seizures start is unclear. Mark Richardson, professor of epilepsy, Institute of Psychiatry, is working on elucidating this question using computational models. He talks Markus Reuber, professor of clinical neurology, University of Sheffield, through his research.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

For more on Professor Richardson’s work on brain models in epilepsy, listen to his previous, recently recorded JNNP podcast http://tinyurl.com/b7n8vya.

BNPA 2013: Cellular mechanisms of epilepsy18 Feb 201300:07:46

Markus Reuber, professor of clinical neurology, University of Sheffield, discusses the different cellular mechanisms which allow seizures in epilepsy to happen, and how this understanding could lead to disease modification with John Jefferys, professor of neuroscience, University of Birmingham.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: Autoimmunity and neuropsychiatry18 Feb 201300:10:56

Tim Nicholson, academic clinical lecturer, Institute of Psychiatry, gives Hugh Rickards, consultant in neuropsychiatry, University of Birmingham, an update on autoimmune mechanisms and encephalitis. Dr Nicholson covers where we are with understanding and treating paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), and also NMDA-receptor encephalitis.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: Deep brain stimulation for mental illness18 Feb 201300:08:50

Eileen Joyce, professor in neuropsychiatry at the Institute of Neurology, gives Hugh Rickards, consultant in neuropsychiatry, University of Birmingham, an update on the use of deep brain stimulation to treat mental disorders, particularly OCD.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: The neural correlates of Freudian “repression” in conversion disorder18 Feb 201300:07:05

Selma Aybek, clinician researcher, Service of Neurology, University of Lausanne, has been examining the process which allows psychological stressors to become physical symptoms in conversion disorder. Chris Butler, academic clinical lecturer in neurology, University of Oxford, asks her what she’s found.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

Drug repurposing for progressive multiple sclerosis02 Mar 202100:08:48
Prof Alaisdair Coles and Dr Nick Cunniffe, The University of Cambridge joins editor Colin Mahoney to discuss:

The work carried out by a team of researchers alongside the MS Society in the United Kingdom. The authors discuss the process of identifying therapies to repurpose in future MS trials and why they think this drugs may work. https://jnnp.bmj.com/content/92/3/295

BNPA 2013: Effects of early childhood posterior fossa tumours on IQ18 Feb 201300:07:35

Cliodhna Carroll, along with colleagues at the University of Cambridge, has shown that children who’ve had a posterior fossa tumour have a lower IQ than matched controls. She talks Chris Butler, academic clinical lecturer in neurology, University of Oxford, through the research and its implications.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: Epilepsy and affective disorders, the role of the subgenual prefrontal cortex18 Feb 201300:07:34

Chris Butler, academic clinical lecturer in neurology, University of Oxford, talks to Rebecca Cleary, research assistant, Wellcome Trust Centre for Neuro-imaging, UCL, about her research investigating whether the neural substrate in those with depression or anxiety is the same as in those with one of these disorders and also temporal lobe epilepsy.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

BNPA 2013: Stress and war, and the limits of neuropsychiatry18 Feb 201300:09:40

Neil Greenberg, academic psychiatrist, Kings College London, who’s served in the armed forces for more than 20 years, argued in his JNNP-sponsored keynote at BNPA that we understand many of the issues in military mental health, and that the neuropsychiatric element is relatively small. Alan Carson, JNNP associate editor, talks to him about the impact of being in the military on mental health beyond PTSD.

This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.

© My Podcast Data · Independent project · Data from Apple & Spotify