Toshi A Furukawa, MD, PhD, Kyoto University, Graduate School of Medicine, School of Public Health, discusses Understanding Bias and Random Error in Medical Research with Gordon H. Guyatt, MD, MSc, McMaster University.

Related Content:

• CONSORT 2025 Statement
• Using Instrumental Variables to Address Bias From Unobserved Confounders

Thomas Agoritsas, MD, PhD, Geneva University Hospitals, Switzerland discusses Users' Guides to the Medical Literature about patient management recommendations with author Gordon H. Guyatt, MD, MSc, McMaster University.

Related Content:

• How to Interpret and Use a Clinical Practice Guideline or Recommendation
• Platelet Transfusion
• Caring for Patients With Acute Respiratory Distress Syndrome

Host Robert M. Golub, MD, discusses How to Interpret and Use a Clinical Practice Guideline or Recommendation with Gordon H. Guyatt, MD, MSc, and Romina Brignardello-Petersen, DDS, MSc, PhD.

Gordon Guyatt, MD, discusses Measuring Agreement Beyond Chance with Thomas McGinn, MD, MPH.

Related Content:

Does This Patient Have Infectious Mononucleosis? The Rational Clinical Examination Systematic Review

Gordon H. Guyatt, MD, MSc, discusses Correlation and Regression with Roman Jaeschke, MD, MSc. 

Gordon Guyatt, MD, discusses economic analysis with Paul Moayyedi, PhD

Gordon Guyatt, MD, discusses Misleading Presentations of Clinical Trial Results with Victor Montori, MD

Related Content:

• Misleading Presentations of Clinical Trial Results with Dr Victor Montori
• When Can Intermediate Outcomes Be Used in Clinical Trials?
• When Guidelines Recommend Shared Decision-making

Anne M. Holbrook, MD and Gordon Guyatt, MD, discuss Surrogate Outcomes from the JAMA Users' Guides to the Medical Literature

Related Content:

• When Can Intermediate Outcomes Be Used as Surrogate Outcomes?
• FDA Acceptance of Surrogate End Points for Cancer Drug Approval: 1992-2019
• What Constitutes a Valid Surrogate End Point in Cancer Clinical Trials?

Interview with Yun Liu, author of How to Read Articles That Use Machine Learning: Users' Guides to the Medical Literature

JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" With William J. Meurer, MD, MS

Ed Livingston, MD, FACS, AGAF, discusses Dose-Finding Trials: Optimizing Phase 2 Data in the Drug Development Process with Kert Viele, PhD

Ed Livingston, MD, FACS, AGAF, discusses Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Amy Kaji, MD, PhD

Mark C. Wilson, MD, MPH, University of Iowa, Carver College of Medicine discusses Evidence-Based Practitioners and Evidence-Based Care with Gordon H. Guyatt, MD, MSc, McMaster University.

Related Content:

Gordon Guyatt, MD, MSc, discusses Decision-making and the Patient with Victor Montori, MD, MSc.

Clinical researchers and biostatisticians use highly specialized language to help them discuss statistics and research methods efficiently. In 2019 JAMA published the JAMA Guide to Statistics and Methods, a book of short reviews that translate that specialized language and explain statistics and methods to a broad physician readership. The book's editors and authors, Edward Livingston, MD, and Roger J. Lewis, MD, PhD, discuss their approach to choosing statistical topics and their objectives in compiling the reviews into book format.

Purchase the JAMA Guide to Statistics and Methods at:

McGraw-Hill:                    ja.ma/StatsGuideMH

Barnes and Noble:           ja.ma/StatsGuideBN

Amazon:                            ja.ma/StatsGuideAmazon

Gordon Guyatt, MD, MSc, discusses the application of the results of systematic reviews and meta-analyses to individual patients with author Thomas Agoritsas, MD.

Dr Edward Livingston discusses How to Use a Subgroup Analysis with Dr Gordon Guyatt

Dr Ed Livingston discusses Composite End Points with Gordon Guyatt

Dr Gordon Guyatt discusses Differential Diagnosis with Scott Richardson

Dr Gordon Guyatt discusses How to Use an Article About Genetic Association with Dr John Attia

Demetrios N. Kyriacou discusses How to Use an Article About Hypothesis Testing and Appropriate Interpretation of P Values with Dr George Tomlinson

Dr David Simel discusses Obstructive Sleep Apnea with Dr Kathryn A. Myers.

Dr Demetrios Kyriacou discusses How to Use an Article About Quality Improvement with Dr Eddy Fan.

Mark C. Wilson MD, MPH, University of Iowa, discusses Teachers' Guides to the Users' Guides with Gordon H. Guyatt, MD, MSc, McMaster University.

Related Content:

• Evidence vs Consensus in Clinical Practice Guidelines
• How to Interpret and Use a Clinical Practice Guideline or Recommendation

Dr Demetrios Kyriacou discusses Network Meta-analysis with Dr Gordon Guyatt.

Dr Amy Thompson discusses the Principle of Intention to Treat and Ambiguous Dropouts with Dr Matthias Briel.

Dr Amy Thompson discusses Evidence-Based Medicine and the Theory of Knowledge with Dr Gordon Guyatt.

Dr Ed Livingston discusses Clinical Prediction Rules with Dr Thomas G. McGinn.

Dr Ed Livingston discusses Recommendations About Screening with Gemma Louise Jacklyn.

Dr Ed Livingston discusses How to Use a Noniferiority Trial with Dr Gordon Guyatt.

Dr Ed Livingston discusses Systematic Review and Meta-analysis with Dr M. Hassan Murad.

Joan Stephenson, PhD, discusses Understanding the Results: More About Odds Ratios with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Why Study Results Mislead with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Surprising Results of Randomized Trials with Dr Gordon Guyatt.

Gordon H. Guyatt, MD, MSc, discusses Assessing the Strength of Recommendations: The GRADE Approach with Per Olav Vandvik, MD, PhD.

Related Content:

• How to Interpret and Use a Clinical Practice Guideline or Recommendation

Joan Stephenson, PhD, discusses Diagnostic Tests with Dr Toshi A. Furukawa.

Joan Stephenson, PhD, discusses Confidence Intervals with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Prognosis with Dr Adrienne Randolph.

Joan Stephenson, PhD, discusses Philosophy of Evidence-Based Medicine with Dr Victor Montori.

Joan Stephenson, PhD, discusses Harm (Observational Studies) with Dr Mitchell Levine.

Joan Stephenson, PhD, discusses Does Treatment Lower Risk?: Interview with Dr Roman Jaeschke.

Joan Stephenson, PhD, discusses Measuring Patients' Experience with Dr Toshi A. Furukawa.

Joan Stephenson, PhD, discusses N-of-1 Randomized Controlled Trials with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Randomized Trials Stopped Early for Benefit with Dr Victor Montori.

Joan Stephenson, PhD, discusses Finding the Evidence with Dr Ann McKibbon.

Host Gordon Guyatt, MD, MSc, discusses Understanding and Applying the Results of a Systematic Review with M. Hassan Murad, MD, MPH.

Related Content:

• How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient Care
• Acute Treatments for Episodic Migraine in Adults

Joan Stephenson, PhD, discusses Summarizing the Evidence with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses The Process of Diagnosis with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Therapy (Randomized Trials) with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses What Is the Question? with Dr Gordon Guyatt.