IDEA Collider: Innovation &amp; Asymmetric Learning in Pharma – Details, episodes &amp; analysis

Seeing Around the Corners By Rita McGrath

To listen to more amazing podcast episodes: https://podcast.ideapharma.com/

Creativity & Innovation In Corporate Venture With Rita McGrath

Season 2 · Episode 5

mercredi 26 octobre 2022 • Duration 59:49

Welcome to another incredible episode of the IDEA Collider│Pharma Book Club series with your host Mike Rea. Today we are joined by a consultant, best-selling author, and one of the world’s top experts on strategy and innovation, Rita McGrath.

In the episode, Rita talks to us about her transition from a political science career to innovation in the corporate venture, how to build an innovation program, challenges in implementation, and why you need multiple funding sources while championing an idea. Additionally, we delve into making that 10x shift in a company, discovery-driven planning, strategic inflection points & best books she would recommend.

Tune in for more innovation insights!

[02:01] About Rita McGrath

[05:10] Rita’s books

[11:55] Tips for building an innovation program

[16:10] Why do companies have one innovation process

[18:45] Reasons companies prefer false confidence instead of the uncertain approach

[27:40] How to get an organization to make a shift to a big place

[34:11] Rita’s thoughts on creativity

[37:25] Why you should have multiple sources of funding & approval

[37:54] Being future forward on failure & interrogating failure

[43:48] Problems related to assumptions in planning

[49:39] Discovery-driven planning

[51:01] Strategic inflection points

[55:05] Books Rita would recommend

[57:16] This or that question (Disruption or innovation)

[58:13] To connect with McGrath

Mentioned Books

Market Busters By Rita McGrath

The End of Competitive Advantage By Rita McGrath

Discovery-Driven Growth By Rita McGrath

Seven Rules of Power By Jeffrey Pfeffer

Thinking Fast & Slow by Kahneman Daniel

Humor Seriously By Jennifer A Aker & Naomi Bagdonas

Let’s Connect!

To Connect With Rita McGrath;

● Website: https://www.ritamcgrath.com/

● Website: https://www.valize.com/

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Website: https://www.ideapharma.com/
Twitter: https://twitter.com/ideapharma
LinkedIn: https://www.linkedin.com/in/bigidea/

To listen to more amazing podcast episodes: https://podcast.ideapharma.com/

Using AI In Drug Discovery With Andrew Hopkins

Season 2 · Episode 4

mercredi 19 octobre 2022 • Duration 50:34

Welcome to another incredible episode of the IDEA Collider│Pharma Book Club series with your host Mike Rea. Today we are joined by Andrew Hopkins, the Founder & CEO of Exscientia, as he talks to us about the use of AI in drug discovery.

In the episode, we delve into Andrew’s journey of developing better drug discovery methods, applying data mining in drug discovery, and the value of data integration in the pharmaceutical industry. Additionally, he expounds on what AI drugs look like and future plans for Exscientia.

Tune in!

During this episode, you will learn about;

[01:12] Introducing Andrew Hopkins & his journey to his current role

[06:27] Applying data mining approach & machine learning

[12:10] What Andrew saw that others were not seeing

[19:06] The value of data integration

[22:02] The role of asking questions & finding answers in tech or data

[26:46] How Hopkins addresses being referred to as the AI discovery group

[33:08] Active learning approaches

[39:06] What an AI drug looks like & what it’s better at

[42:17] The future of AI drugs & Exscientia future plans in establishing clinics

[46:34] What do the next couple of years look like regarding solutions Andrew wished he had 5-10 years ago?

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Mentioned Books

Ideas-A History From Fire To Freud by Peter Watson

Where Good Ideas Come From by Steven Johnson

Let’s Connect!

Follow Exscientia on;

● Website: https://www.exscientia.ai/

● LinkedIn: https://www.linkedin.com/company/ex-scientia/

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To listen to more amazing podcast episodes: https://podcast.ideapharma.com/

The Misconceptions In The Pharma Industry With John L. Lamattina

Season 2 · Episode 3

mercredi 12 octobre 2022 • Duration 01:02:56

In this incredible episode, Mike Rea is joined by Dr. John L. LaMattina. John is the former Senior Vice President of Pfizer Inc and President of Pfizer Global Research & Development. Additionally, he is a senior partner at PureTech Health and an author. He talks about the misconception about Pfizer’s profiteering from the pandemic and the drug pricing in America.

John also discusses how Gilead’s Sovaldi drug for hepatitis C became overpriced in the US and the effects of insurance companies on the drug market. Moreover, he talks about the misinformation about insulin and its pricing, NIH’s role in drug discovery research, and the profitability of the pharma industry.

Tune in!

During this episode, you will learn about;

[00:22] Introduction to the show

[0:42] Know our guest; Dr. John L. LaMattina, and why he has authored his books

[04:58] Misconception about Pfizer’s profiteering from the pandemic

[08:13] Drug pricing in America

[12:35] Gilead’s Sovaldi drug for hepatitis C and how it became overpriced in the US more than in other countries

[19:57] The cost-effectiveness of PCSK9 in regulating (low-density lipoprotein) LDL cholesterol

[21:42] Effect the insurance companies have had on the drug market

[26:09] Value of the ‘me-too’ drugs

[30:01] The inefficiency of the flu vaccines

[33:03] The funding for early-stage mRNA vaccines

[34:23] The input of the FDA and CDC in the manufacture of mRNA vaccines

[37:46] What is NIH’s role in drug discovery research?

[38:13] The process and cost of drug discovery; from idea to getting the drug approved

[42:39] Misinformation about insulin and its pricing

[47:21] Is the value vs. affordability of medicines a reputation challenge or a commercial challenge for the industry?

[51:31] What’s the profitability of the pharma industry?

[59:48] Recommended reading

[01:02:38] How to connect with us

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Resources Mentioned

Book; Pharma and Profits by John L. LaMattina

Book; Devalued and Distrusted by John L. LaMattina

Book; Drug Truths by John L. LaMattina

Book; The Great American Drug Deal by Peter Kolchinsky

Let’s Connect!

Website: https://www.johnlamattina.com/

Twitter: https://twitter.com/john_lamattina

LinkedIn: https://www.linkedin.com/in/john-lamattina-2985a9b/

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To listen to more fantastic podcast episodes: https://podcast.ideapharma.com/

Asymmetric Learning in Cybersecurity & Intelligence with Gene Yoo

Season 2 · Episode 2

mercredi 5 octobre 2022 • Duration 47:23

Welcome to another fantastic episode of the IDEA Collider│Asymmetric learning series with your host Mike Rea. Today we are joined by Gene Yoo, the Chief Executive Officer at Resecurity, Inc. He talks about asymmetric learning in cybersecurity & Intelligence and what gives Resecurity an edge over other competitors in the market

Moreover, he shares about the signal validation process at Resecurity, how to understand the vulnerability of your business and what you need to combat cyber threats. In addition, Gene talks about the ‘what if’ component in their learning approach and the leadership style & culture at Resecurity.

Tune in!

During this episode, you will learn about;

[00:23] Introduction to the show

[01:23] What this series is about; Asymmetric learning

[04:41] Definition of insight in cybersecurity

[07:07] What is cyber threat intelligence about, and how should threat intelligence data be interpreted to deliver actionable insights?

[10:37] Security theater

[14:40] How Resecurity identifies a threat

[19:58] Understanding the vulnerability of your business and what you need to combat cyber threats

[22:52] Do they provide threat solutions or just threat evidence?

[24:22] The ‘what if’ component in their learning approach

[27:36] What gives Resecurity an edge over other cybersecurity & Intelligence companies in the market?

[29:19] Signal validation process at Resecurity

[31:00] The source of their data

[34:29] Resecurity leadership style and culture

[39:40] Prototyping at Resecurity

[42:49] Does Gene prefer a disruptor or an innovator?

[44:59] What’s the future of Resecurity in 5 years?

(46:33] How to connect with Gene Yoo

Don’t forget to Subscribe, Rate, Review, Like, and Share!

Let’s Connect!

Follow Gene Yoo on;

Website: https://resecurity.com/

LinkedIn: https://www.linkedin.com/company/resecurity/

Facebook: https://bit.ly/3vqMfzS

Twitter: https://twitter.com/RESecurity

Vimeo: https://vimeo.com/user153388997

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To listen to more amazing podcast episodes: https://podcast.ideapharma.com/

Where Do Good Ideas Come from? With Steven Johnson

Season 2 · Episode 1

mercredi 28 septembre 2022 • Duration 58:33

Welcome to another fantastic episode of the IDEA Collider│Asymmetric learning series with your host Mike Rea. In today’s episode, Mike interviews Steven Johnson, an author of 13 books, a TV host, and a podcaster. He talks about Innovation vs. Invention and explains where good ideas come from.

Additionally, Steven talks about the Individual and organizational hunch collection tools and shares how organizational culture impacts innovation. Moreover, he talks about his books The Ghost Map and Farsighted.

Tune in!

During this episode, you will learn about;

[01:05] Meet Steven Johnson and hear his backstory

[03:03] Innovation vs. Invention

[05:26] Where do good ideas ‘soul hunches’ come from?

[09:32] Reason why play and delight are linked to profound innovation

[12:52] Organizational culture and innovation

[17:12] How the daily schedule for his writing work looks like

[10:1414] Steven’s discovery process

[26:59] How Steven uses Twitter as a source of scientific discovery

[30:58] Individual and organizational hunch collection tools

[39:10] The Ghost Map and how it evolved from the format to a published book

[46:34] Farsighted: How We Make the Decisions That Matter the Most

[55:11] How to connect with Steven Johnson

Remember to Follow, Rate, Review, Like, and Share!

Resources Mentioned

Book; The Ghost Map by Steven Johnson

Book; Farsighted by Steven Johnson

Book; How We Got to Now by Steven Johnson

Book: Wonderland by Steven Johnson

Let’s Connect!

Follow Steven Johnson on;

Website: https://stevenberlinjohnson.com/

Twitter: https://twitter.com/stevenbjohnson

Subscribe to his Newsletter at: https://adjacentpossible.substack.com/about

To grab a copy of any of Steven’s Books: https://amzn.to/3L3zUrV

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Follow Mike Rea on;

To listen to more fantastic podcast episodes: https://podcast.ideapharma.com/

Welcome Back to Series II of IDEA Collider

Season 2

mercredi 28 septembre 2022 • Duration 00:47

Sick Money: The Truth About The Global Pharmaceutical Industry With Billy Kenber

Season 1

mercredi 22 juin 2022 • Duration 58:06

Welcome to another fantastic episode of the IDEA Collider│Pharma Book Club series with your host Mike Rea. Today we are joined by Billy Kenber, an investigative journalist at “The Times.” He talks about his journey to writing his book ‘Sick Money’ and the content in the book.

Additionally, he talks about the pharmaceutical industry’s social contract with patients and how its distortion has led to pharmaceutical greed. Moreover, he shares how the culture within the pharmaceutical industry has changed, why drug companies overprice the drugs, and what can be done to regulate drug pricing.

Tune in!

During this episode, you will learn about;

[00:22] Episode introduction

[01:08] Meet our guest; Billy Kenber

[01:22] His journey to writing his book ‘Sick Money’

[03:28] What the book is about

[06:11] How Concordia Pharmaceuticals & Valeant Pharmaceuticals companies

grew quickly and gained a short-term monopoly, thus hiking the drug prices

[10:40] What’s the geographical scope of the pharmaceutical fraud

[12:47] Pharmaceutical industry’s social contract with patients and how its distortion has led to pharmaceutical greed

[15:20] The first AIDS drug; AZT

[18:30] A background of AZT drug high pricing and how it led to other

pharmaceutical companies raising their prices

[22:47] How Pharmacy Benefit Managers (PBMs) raise drug prices for patients

[25:39] The ’Dirty Pharma’ chapter in his book

[28:45] Why drug companies overprice the drugs

[29:17] How the culture within the pharmaceutical industry has changed

[30:52] Pharmaceutical innovation after World War II; Antibiotics

[35:29] mRNA vaccines in the COVID-19 pandemic

[37:28] Effect of cultural changes in the pharmaceutical industry on the drugs we

get and how Research and Development (R&D) is done

[40:30] How cultural changes have affected orphan drugs and cancer drugs

[46:30] What can be done to regulate drug pricing?

[53:50] Recommended reading

[56:00] How to connect with Billy

Love the show? Follow, Rate, Review, Like, and Share!

Let’s Connect!

Follow Billy Kenber on his;

Website: https://www.billykenber.com/

Twitter: https://twitter.com/billykenber

Linkt.ree: https://linktr.ee/billykenber

To grab a copy of the ‘Sick Money’ book: https://amzn.to/3N4XJPD

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