Welcome to the Hope and Help for Fatigue and Chronic Illness Podcast. It's our mission to help people that have some really complicated illnesses. People that have post viral syndrome like long COVID and ME/CFS or chronic fatigue. Those that have had toxic exposures like gulf war illness, mold exposures, pesticides and heavy metals.
These illnesses can present very similarly, they can actually look the same to your clinician.
You may have fatigue, post exertional malaise, foggy brain and many other symptoms that seem to be common across many illnesses. Underneath all of these illnesses, the causes of the symptoms are very similar. We know first hand how hard it is to get access to meaningful information and care when you find yourself or a loved one here. It is our hope to give you, bit by bit, the knowledge and ideas that we have seen make a positive impact on individuals just like you. And that you will take all those threads and begin to weave back together a healthier person.
Brought to you by the Institute for Neuro-Immune Medicine where we have over 200 years of combined clinical experience in Neuro-Inflammatory disease.
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In this episode, we compile selected highlights from the most impactful podcasts of 2025, featuring insights and clinical perspectives from leading experts, including Dr. Richard C. Deth, Dr. Marc Kesselman, Dr. Nancy Klimas, Dr. Payam Hakimi, and Dr. Philip DeFina. Together, they address critical topics such as ME/CFS, Long COVID, and neuroinflammation.
This episode also highlights key themes frequently explored throughout the year, including optimizing metabolic health, the essential role of nutrient-dependent healing, and the impact of environmental toxins and mycotoxins on the body. The experts further share insights into homeopathy, post-traumatic symptoms following neuroinflammation, and the biological and lifestyle factors that help protect brain health.
Ultimately, this compilation underscores the importance of communication, trust, and patient-centered relationships in delivering effective care and supporting meaningful healing outcomes.
Dr. Richard Deth is a molecular neuroscientist at Nova Southeastern University, where he has worked since 2014 after 38 years at Northeastern University. His research focuses on brain disorders like autism, exploring neurodevelopment, aging, attention, and learning. He studies neurons' metabolic features, particularly the antioxidant glutathione (GSH), its role in methylation, and epigenetic regulation. Dr. Deth investigates how casein and gluten-derived opioid peptides impair cysteine absorption, affecting antioxidant levels and epigenetics. His current work examines oxidative stress, inflammation, and the anti-inflammatory potential of cobinamide, a vitamin B12 precursor.
Dr. Marc Kesselman is the chair and associate professor at the Department of Internal Medicine at Dr. Kiran C. Patel College of Osteopathic Medicine. He is also the chief of the Division of Rheumatology at Nova Southeastern University. Dr. Kesselman received his medical degree from Des Moines University College of Osteopathic Medicine and has been in practice for more than 20 years.
Dr. Nancy Klimas, a clinical immunologist by training, is the director of the Institute for Neuro-Immune Medicine who has allotted her life to helping other people find cures for their complex illnesses that were once considered helpless. She works with her fellow medical experts in researching and analyzing the deeper causes of such diseases, particularly on the neuro-immunity side, to provide the best option suited for every single case or story they handle.
Dr. Payam Hakimi is the Medical Director of Body of Harmony in Beverly Hills, CA, and Miami, FL, offering a range of services including Functional Medicine, Anti-aging Medicine, Hormone Replacement Therapy, Clinical Homeopathy, and IV Nutrition Therapy. A board-certified Doctor of Osteopathic Medicine, Dr. Hakimi blends conventional and complementary medicine with a personalized approach to care. He earned his DO from Western University of Health Sciences, completed his residency at LAC+USC, and served as Chief Resident and Assistant Clinical Professor at USC Keck School of Medicine. A national leader in homeopathic education, Dr. Hakimi is a senior faculty member at the CEDH and the only U.S. physician to consistently lecture on homeopathy at medical conferences, sharing his expertise with diverse healthcare audiences.
Dr. Philip DeFina has over 40 years of experience as a neuropsychologist and cognitive neuroscientist. He is most known for developing novel, groundbreaking treatment protocols for traumatic brain injury, coma, autism spectrum, and PTSD. He is the founder and Chief Scientific Officer of the International Brain Research Foundation (IBRF). Dr. DeFina previously served on the NYU faculty as an associate professor of neurology and psychiatry at the New York University School of Medicine and the Bellevue Hospital Center. He was a forensic neuropsychologist at the Mount Sinai-Elmhurst Hospital Medical Center and was an adjunct professor at the University of Maryland Psychology Department. Dr. DeFina was also the founder and first director of the Fielding Graduate University's Post-Doctoral Clinical Neuropsychology Training Program. Dr. DeFina subsequently co-founded the school neuropsychology training program at Texas Women's University and co-founded the American Board of School Neuropsychology, and was one of the original founding members of the American Board of Pediatric Neuropsychology.
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
In this episode, Haylie Pomroy speaks with Dr. Theoharis Theoharides about multiple chemical sensitivity (MCS). He explains the immunological responses occurring within the body, the symptoms and daily experiences reported by patients, and the connection between MCS and mast cell activation.
Dr. Theoharides also offers expert guidance on managing MCS, explains the diagnostic codes associated with mast cell activation, and emphasizes why blocking mast cells is critical to the healing process.
He further discusses how stress can trigger mast cell reactivation, the role of vitamin D3, and why measuring chemical exposures and mycotoxins does not always indicate the absence of ongoing immune reactivation.
Dr. Theoharis Theoharides is a Professor, Vice Chair of Clinical Immunology, and Director at the Institute for Neuro-Immune Medicine-Clearwater, an Adjunct Professor of Immunology at Tufts School of Medicine, where he was a Professor of Pharmacology and Internal Medicine, and also the Director of Molecular Immunopharmacology & Drug Discovery, and Clinical Pharmacologist at the Massachusetts Drug Formulary Commission (1983-2022). He received his BA, MS, MPhil, PhD, and MD degrees and the Winternitz Price in Pathology from Yale University and received a Certificate in Global Leadership from Tufts Fletcher School of Law and Diplomacy and a Fellowship at Harvard Kennedy School of Government. He trained in internal medicine at New England Medical Center, which awarded him the Oliver Smith Award, "recognizing excellence, compassion, and service." Dr. Theoharides has 485 publications (46,491 citations; h-index 106), placing him in the world's top 2% of most cited authors, and he was rated the worldwide expert on mast cells by Expertscape. He was inducted into the Alpha Omega Alpha National Medical Honor Society, the Rare Diseases Hall of Fame, and the World Academy of Sciences.
Website:
EP73: The Science of Stress: Tools to Reclaim Your Health
Why is the stress response an essential part of our wellbeing?
Dr. Jaime Tartar shares a conversation with Haylie Pomroy to tackle how stress impacts both our physical health and overall wellbeing, and how we can address it.
They dive into the science of stress response, the differences between acute and chronic stress, and the critical role of sleep in stress management. Dr. Tartar also shares practical strategies for controlling our thoughts, improving sleep quality, and explains how stress is processed during catastrophic events.
Learn more on the Hope and Help for Fatigue and Chronic Illness Podcast: The Science of Stress: Tools to Reclaim Your Health
Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others. You can also catch this show on YouTube and other podcast platforms.
Showing empathy to patients and truly being in their shoes is how we begin to redefine care.
Today, Haylie Pomroy is joined by Nurse Practitioner Irina Rozenfeld to talk about how personalized care for chronic illness can help improve and redefine the way we approach healthcare today.
Dr. Rozenfeld shares her formula for helping patients gain access to adequate care, the role of empathy in building strong therapeutic relationships, and how her advocacy work also empowers patients to become advocates for themselves.
Together, they dig deep into personalized medicine, the impact of knowledge deficit in healthcare, and how a patient can more effectively communicate with their practitioner to achieve the best outcomes.
Learn more on the Hope and Help for Fatigue and Chronic Illness Podcast: Redefining Care: Personalized Medicine for Chronic Illness
Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others. You can also catch this show on YouTube and other podcast platforms.
If you are interested in joining a Gulf War Illness (GWI) trial, please complete the Recruitment Registry Form.
EP71: What Spike Proteins Reveal About Long COVID and ME/CFS
Tuesday, September 2, 2025 • Duration 40:26
Why are some people still sick long after COVID clears?
Dr. Nancy Klimas, immunologist and Director of the Institute for Neuro-Immune Medicine, joins Haylie Pomroy to explain how persistent spike protein may be the missing link behind long COVID.
They explore how this protein triggers immune dysfunction, brain fog, fatigue, and symptoms nearly identical to ME/CFS. Dr. Klimas shares what separates those who recover from those who don't, and the emerging clinical trials that may offer real answers.
Learn more on the Hope and Help for Fatigue and Chronic Illness Podcast: What Spike Proteins Reveal About Long COVID and ME/CFS.
Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others. You can also catch this show on YouTube and other podcast platforms.
Watch "Exercise as Medicine: When It Helps and When It Hurts" with Jeffrey Cournoyer here:
If you are interested in joining a Gulf War Illness (GWI) trial, please complete the Recruitment Registry Form.
EP70: The Hidden Keys to Autoimmune Health
Tuesday, August 19, 2025 • Duration 45:07
In this episode, Haylie Pomroy sits down with Dr. Marc Kesselman, a rheumatologist who's helped thousands navigate conditions like lupus, rheumatoid arthritis, and long COVID.
Together, they discuss why these diseases are becoming more common, the surprising ways viruses and toxins can trigger them, and what "pre-autoimmunity" testing can reveal years before symptoms even start.
Haylie also opens up about her own autoimmune journey, and why they both believe nutrition, stress management, and finding a doctor who truly listens can change the course of your health.
If you've ever feared a flare, struggled to get answers, or just want to protect your immune system, this conversation will give you science, strategies, and hope you can use right now.
Tune in to the Hope & Help for Fatigue and Chronic Illness Podcast - The Hidden Keys to Autoimmune Health.
Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others. You can also catch this show on YouTube and other podcast platforms.
Dr. Marc Kesselman is Chair of the Department of Internal Medicine at KP COM and Chief of the Division of Rheumatology. He specializes in autoimmune disease diagnosis, management, and prevention, with a focus on integrating nutrition, lifestyle, and patient communication into care.
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
When living with ME/CFS or Long COVID, even getting out of bed can feel like running a marathon.
In this episode, Haylie Pomroy sits down with Dr. David Systrom, a Harvard physician and Director of the Advanced Cardiopulmonary Exercise Lab at Brigham and Women's Hospital to talk about exercise intolerance for people with chronic illnesses and why so many patients are left without answers.
Dr. Systrom shares findings from invasive cardiopulmonary exercise testing and explains why traditional tests often miss what patients are actually experiencing. They dig into post-viral illness, mitochondrial dysfunction, dysautonomia, and the promise of clinical trials that could lead to more compassionate and targeted care.
Tune in to the Hope and Help for Fatigue and Chronic Illness Podcast - Advancements in ME/CFS and Long COVID Care.
Dr. David Systrom, MD. is the Director of the Advanced Cardiopulmonary Exercise Laboratory at Brigham and Women's Hospital and Assistant Professor at Harvard Medical School. His work focuses on uncovering the mechanisms of exercise intolerance and helping build more precise, effective treatments for patients with ME/CFS and Long COVID.
Want to help advance research in ME/CFS and Long COVID?
You may be eligible to join The LIFT Trial and the Mitochondrial Muscle Study.
Reach out to: Johanna Squires, Senior Clinical Trial Coordinator
In this episode, Haylie Pomroy shares a conversation with Dr. Angela Taylor, a board-certified Clinical Nutritionist and expert in Functional Medicine, to discuss how nutrition impacts the endocrine system, immune system, and nervous system.
Dr. Taylor shares how she supported a family member with autism in managing symptoms through targeted nutritional strategies. She explains why a gluten-free diet is often the first line of defense against inflammation and outlines a nutritional protocol tailored for individuals on the spectrum.
She also introduces her book, "The BrainFood Cookbook," which advocates for a grain-free diet. The conversation explores the concept of the nutrition ladder, gut dysbiosis, and the scientific basis for food allergies and sensitivities.
Tune in to the Hope and Help for Fatigue and Chronic Illness Podcast - The Nutrition Ladder: A New Approach to Chronic Symptoms.
In this episode, Dr. Theoharis Theoharides breaks down the science behind Multiple Chemical Sensitivity (MCS), offering a clear and research-informed perspective on this often misunderstood condition.
He defines what MCS is, how individuals can be triggered by even minimal chemical exposures, and the wide range of symptoms that may follow. He also addresses the serious immunological effects of chemical exposure and emphasizes the importance of creating chemically safe environments.
The discussion also covers the role of mast cell activation in MCS, the ways stress can intensify symptoms, and the diagnostic codes currently used for clinical management and treatment.
Tune in to the Hope and Help for Fatigue and Chronic Illness Podcast – The Science Behind Chemical Sensitivity
In this episode, Haylie Pomroy shares a conversation with Dane Johnson, a board-certified Functional Nutritionist, focusing on inflammatory bowel disease (IBD), including Crohn's disease.
Dane discusses the power of community in the healing process, why IBD prevalence is increasing, and how man-made chemicals disrupt the microbiome.
He emphasizes the importance of gut healing and explores biomarkers and symptom profiles specific to Crohn's disease. He also covers the critical connection between the nervous system and IBD, and introduces the S.H.I.E.L.D. program, designed to help individuals find personalized answers to chronic illness.
Drawing from his own journey from illness in childhood to healing, Dane helps others reclaim their health and move beyond limiting beliefs.
Tune in to the Hope and Help for Fatigue and Chronic Illness Podcast: Healing IBD Naturally: The Mind-Gut Approach.
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Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
Jaime Tartar is a Professor of Neuroscience at Nova Southeastern University. She earned her Ph.D. in the Behavioral Neuroscience program at the University of Florida, where the focus of her research involved discovering long-term changes that occur in neurobiological pathways involved in stress responses and developing animal models of stress. Dr. Tartar has also completed Postdoctoral Training at Harvard Medical School, where she studied the neurological consequences of sleep perturbations using in vitro electrophysiological recording techniques. She also received training in Sleep Medicine at Harvard Medical School. She was also awarded an Honorary Doctorate at Nova Southeastern University. Dr. Tartar is the co-founder and CEO of The Society for Sports Neuroscience, an academic organization for the field of Sports Neuroscience. Dr. Tartar's current research is focused on stress, sleep, and athletic performance in humans.
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
Irina Rozenfeld, DNP, MSHS, APRN, ANP-BC is is a Board Certified Nurse Practitioner committed to the health of her patients. Irina emphasizes patient-practitioner relationships, critical thinking, and patient education to develop an optimal treatment plan and achieve sustainable results. She obtained her Bachelor's of Science degree from Nova Southeastern University and a Master's of Science in Nursing Studies from Florida International University. Additionally, she has obtained a Master's degree in Integrative Medicine from George Washington University School of Medicine and a Doctoral degree at the University of North Florida. Before joining the INIM, Irina worked for more than twenty years as a physician assistant in Russia. After relocating to Florida, she worked as a Clinical Research Nurse at Nova Southeastern University. Irina obtained an international certification as a Clinical Research Professional and has been involved in research in many roles. Irina teaches at Nova Southeastern University College of Nursing as an adjunct faculty.
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
Dr. Angela Taylor is a Clinical Nutritionist based in Baltimore, MD. She has her private practice (BrainFood Nutrition) and also serves as Adjunct Faculty at Johns Hopkins University, teaching Clinical Nutrition. Her specialty areas include Gluten-Free, Autism, ADHD, Sports Nutrition, and Herbal Medicine.
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
Dr. Theoharis Theoharides is a Professor, Vice Chair of Clinical Immunology, and Director at the Institute for Neuro-Immune Medicine-Clearwater, an Adjunct Professor of Immunology at Tufts School of Medicine, where he was a Professor of Pharmacology and Internal Medicine, and also the Director of Molecular Immunopharmacology & Drug Discovery, and Clinical Pharmacologist at the Massachusetts Drug Formulary Commission (1983-2022). He received his BA, MS, MPhil, PhD, and MD degrees and the Winternitz Price in Pathology from Yale University and received a Certificate in Global Leadership from Tufts Fletcher School of Law and Diplomacy and a Fellowship at Harvard Kennedy School of Government. He trained in internal medicine at New England Medical Center, which awarded him the Oliver Smith Award, "recognizing excellence, compassion, and service." Dr. Theoharides has 485 publications (46,491 citations; h-index 106), placing him in the world's top 2% of most cited authors, and he was rated the worldwide expert on mast cells by Expertscape. He was inducted into the Alpha Omega Alpha National Medical Honor Society, the Rare Diseases Hall of Fame, and the World Academy of Sciences.
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
Dane Johnson is a board-certified Functional Nutritionist and a Natural Medicine Practitioner specializing in Crohn's Disease and Ulcerative Colitis. He is the founder of CrohnsColitisLifestyle. He combines self-empowering resolve with holistic unity, the drive of an entrepreneur with the idealism of a Millennial inspired to make an impact. He has helped thousands of people eliminate their symptoms naturally and handled all public speaking, video content, market strategy, and managed a team of 10+ employees with the mission to create the most impactful Crohn's/Colitis program in the world.
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com