Moderator: Melinda Magyari (Copenhagen, Denmark)

Guest: Celia Oreja-Guevara (Madrid, Spain)

In this last August episode Melinda Magyari hosts Celia Oreja-Guevara as they explore the impact of MS on women's fertility, the shift in advice regarding pregnancy, and how pregnancy affects MS activity. They also discuss the importance of consulting a neurologist, considerations for artificial reproduction techniques, and recommendations for disease-modifying therapies, including treating relapses during pregnancy and breastfeeding.

Moderator: Melinda Magyari (Copenhagen, Denmark)

Guest: Thomas Berger (Vienna, Austria)

Melinda Magyari and her guest Thomas Berger talk about how aging affects MS progression and management, focusing on immunosenescence's impact on the immune response and DMT effectiveness. They cover the rise of comorbidities in older MS patients, the challenges of using DMTs over age 55, the lack of clinical trials for this age group, and share lifestyle tips to improve quality of life and health outcomes.

Moderator: Barbara Tettenborn (St. Gallen, Switzerland)

Guests: Claudio Bassetti (Bern, Switzerland) and Elena Moro (Grenoble, France)

We are thrilled to announce a milestone celebration: the 100th episode of eanCast!

In this special episode, we are honoured to welcome two distinguished guests. The past president of EAN, Prof. Claudio Bassetti, who will share insights into the challenges faced and achievements accomplished during his tenure, along with exciting projects that have made a lasting impact. Additionally, we will be joined by the first female future president of EAN: Prof. Elena Moro, who will discuss her vision and plans for her upcoming presidency.

Moderator: Prof. Barbara Tettenborn (St. Gallen, Switzerland) 
Guest: Prof. Claudio Bassetti (Bern, Switzerland) 
For this special episode Prof. Barbara Tettenborn sits down Prof. Claudio Bassetti, former President of the European Academy of Neurology, to talk about the recent brain health strategy and the importance of brain health

Moderator: Prof. Barbara Tettenborn (St. Gallen, Switzerland)
Guest: Dr. Cheryl Carcel (Sydney, Australia)
For the final episode focusing on Stroke Prof. Barbara Tettenborn meets with Dr. Cheryl Carcel, academic lead of the Sex Differences in Stroke Group, to talk about the gender differences of stroke epidemiology, as well as management and outcome.

Moderator: Prof. Barbara Tettenborn (St. Gallen, Switzerland) 

Guest: Prof. Dr. Thorsten Steiner (Frankfurt, Germany) 

Prof. Barbara Tettenborn speaks with Prof. Dr. Thorsten Steiner about the etiology, diagnosis and management of intracerebral hemorrhages.

Moderator: Prof. Barbara Tettenborn (St. Gallen, Switzerland)
Guest: Prof. Simon Jung (Bern, Switzerland)
Prof. Barbara Tettenborn speaks with Stroke specialist Prof. Simon Jung to gain insight on acute stroke care in pre-hospital phase and developments in the field.

Moderator: Prof. Barbara Tettenborn (St. Gallen, Switzerland)

Guest: Prof. Hanne Krarup Christensen (Copenhagen, Denmark)

This month’s moderator Prof. Barbara Tettenborn speaks with Stroke Specialist Prof. Hanne Krarup Christensen to cover the burden, prevention, treatment and care, as well as life after Stroke.

Moderators: Prof. Thomas Berger (Vienna, Austria) and Dr. Ambra Stefani (Innsbruck, Austria)

Guest: Prof. Claudio Bassetti (Bern, Switzerland)

The final episode focusing on Sleep-Wake disorders brings together the monthly moderators, Prof. Berger and Dr. Stefani, with Prof. Claudio Bassetti to discuss controversies and other hot topics in narcolepsy.

Moderators: Prof. Thomas Berger (Vienna, Austria) and Dr. Ambra Stefani (Innsbruck, Austria)

Guest: Leontien Sickenga (The Netherlands)

Prof. Berger and Dr. Stefani meet with Ms. Leontien Sickenga, a founding member and the Vice-President of the European Narcolepsy Alliance for Patients (eNAP) to discuss the affects of narcolepsy, diagnosis, and treatment from a patient’s point-of-view. 

Moderators: Prof. Thomas Berger (Vienna, Austria) and Dr. Ambra Stefani (Innsbruck, Austria)

Guest: Dr. Rolf Fronczek (Leiden, Netherlands)

Prof. Berger and Dr. Stefani speak with somnologist, Dr. Rolf Fronczek, about diagnosing and treating narcolepsy, as well as anticipated future developments in the field. 

Moderators: Prof. Thomas Berger (Vienna, Austria) and Dr. Ambra Stefani (Innsbruck, Austria)

Guest: Dr. Evelina Pajediene (Vilnius, Lithuania)

Prof. Berger and Dr. Stefani speak with sleep specialist Dr. Evelina Pajediene about the basics of sleep complaints and sleep-wake disorders, as well as what students and new residents will need to know about sleep-wake disorders.

Moderators: Prof. Thomas Berger (Vienna, Austria) and Dr. Ambra Stefani (Innsbruck, Austria)

Guest: Prof. Barbara Tettenborn (St. Gallen, Switzerland)

This month’s moderators, Prof. Thomas Berger and Dr. Ambra Stefani, discuss the release of the eanCampus, the innovative new eLearning platform from EAN, as well as the current status of eLearning in Neurology.

Moderator: Barbara Tettenborn (St. Gallen, Switzerland)

Guest: Jutta Keller (Hamburg, Germany)

In this episode of eanCast and UEG Talks, host Prof. Barbara Tettenborn from the EAN and guest Prof. Jutta Keller from UEG discuss neuro-gastroenterology, focusing on the gut-brain axis and its implications for various gastrointestinal and neurological disorders. They explore the influence of the microbiome on gut function, the impact of diet on brain health, and strategies for managing gastrointestinal symptoms in patients with neurological conditions like Parkinson's disease.

United European Gastroenterology (UEG) is a strategic partner of the Brain Health Mission (BHM). This episode is brought to you by the Brain Health Mission.

Moderator: Alicia Gonzalez (Madrid, Spain)

Guest: Christian Lampl (Linz, Austria)

This last May episode features Alicia González Martínez and her guest Prof. Christian Lampl as they discuss organising headache care, focusing on increasing access and offering value-based healthcare. They delve into strategies to improve the delivery, efficiency, and cost-effectiveness of headache management, aiming to enhance patient well-being and integration of headache care into existing healthcare systems.

Moderator: Daniele Martinelli (Pavia, Italy)

Guest: Raquel Gil-Gouveia (Oeiras, Portugal)

Guest: Antoinette Maassen van den Brink (Rotterdam, The Netherlands)

Join us in this episode as Daniele Martinelli engages in a dialogue with esteemed experts, Prof. Antoinette Maassen van den Brink and Dr. Raquel Gil-Gouveia.

They delve into animal models—our window into the brain’s hidden mechanisms. These models reveal neurotransmitter dynamics and potential triggers, paving the way for novel therapies. Additionally, they explore gender-specific nuances, shaping the understanding and personalized management strategies. By bridging theory to practice, they emphasize collaboration—a path toward better patient outcomes, alleviating the burden of this debilitating condition.

Moderator: Anna Gryglas-Dworak (Wroclaw, Poland)

Guest: Dimos-Dimitrios Mitsikostas (Athens, Greece)

This podcast episode presents the current guidelines of the European Headache Federation (published in 2021, updated in 2022) and the American Headache Society (2024) on migraine treatment. Acute and preventive as well as new and old options are discussed.

Moderator: Bianca Raffaelli (Berlin, Germany)

Guest: Messoud Ashina (Copenhagen, Denmark)

Guest: Cristina Tassorelli (Pavia, Italy)

In this episode, Bianca Raffaelli hosts experts Messoud Ashina and Cristina Tassorelli on how to navigate the newly enriched therapeutic armamentarium of migraine with disease-specific drugs for the prevention and the acute treatment of attacks. They delve into the questions how, when, where, who and for whom.

Moderator: Giovanni Palermo (Pisa, Italy)

Guest: Sterre van der Veen (Groningen, The Netherlands)

In this episode, Giovanni Palermo and Sterre van der Veen explore the myoclonus phenomenon from its semiology to treatment, while dissecting the complexity of classification systems aimed at recognising its nature and determining its underlying causes.

In this episode Iva Stankovic hosts Alessio Di Fonzo to discuss how to diagnose chorea and how to approach differential diagnosis to entangle the etiology of chorea.

Moderator: Yildiz Degirmenci (Istanbul, Turkey)

Guest: Vladimira Vuletic (Rijeka, Croatia)

In this episode Yildiz Degirmenci and Vladimira Vuletic cover the approach to dystonia emergencies. Dystonia, marked by muscle contractions and abnormal movements, can be triggered by medications like antipsychotics. Management includes stopping triggering drugs and using medications like diphenhydramine. Status dystonicus, a severe form, requires intensive care with oxygen or ventilation. Primary and secondary dystonias are prone to this condition, possibly needing medication adjustments or deep brain stimulation. They stress the significance of patient history for precise diagnosis and treatment.

Moderator: Yildiz Degirmenci (Istanbul, Turkey)

Guest: Christos Ganos (Berlin, Germany)

Yildiz Degirmenci hosts a discussion with Christos Ganos, a movement disorder specialist, about ticks and Tourette syndrome. They delve into the definition of ticks, discuss diagnostic criteria, and differentiate between primary and functional tic disorders. The conversation also covers treatment options, including psychoeducation, psychological interventions like cognitive behavioral therapy, pharmacological treatments such as antipsychotics, and invasive neuromodulation methods.

Moderator: Melinda Magyari (Copenhagen, Denmark)

Guest: Nikolaos Grigoriadis (Thessaloniki, Greece)

Melinda Magyari hosts Paolo Preziosa as they delve into the significance of central vein sign and chronic active lesions in multiple sclerosis diagnosis and prognosis. They explore how these MRI biomarkers enhance diagnostic accuracy and predict disease progression, emphasizing their potential clinical relevance and the need for further research to optimize MS treatment strategies.

Moderator: Rolf Fronczek (Leiden, The Netherlands)

Guest: Marina Tüzün (Bern, Switzerland)

Rolf Fronczek and Marina Tüzün discuss the Burden of Sleep Disorders Project, targeting daytime sleepiness and insomnia across Europe. They emphasize primary care collaboration for effective management, including patient perspectives and long-term follow-ups. Dr. Tüzün's personal interest in sleep research drives her involvement, inviting listeners to stay updated on the project's progress.

Moderator: Francesco Di Lorenco (Rome, Italy)

Guest: Dag Aarsland (London, United Kingdom)

Francesco Di Lorenco and Prof. Dag Aarsland discuss managing behavioral symptoms in dementia, highlighting the burden on patients and families. They stress the importance of timely treatment and challenges in diagnosis. They mention brexpiprazole's FDA approval for Alzheimer's agitation and the need for careful monitoring. Early detection of psychiatric symptoms in neurological diseases is crucial, but distinguishing between disorders is challenging. Therapeutic options like clozapine and cholinesterase inhibitors are mentioned, calling for more research and collaboration.

Moderator: Massimo Filippi (Milan, Italy)

Guest: Federica Agosta (Milan, Italy)

In this week’s episode Prof. Massimo Filippi and Prof. Federica Agosta discuss frontotemporal dementia (FTD) emphasizing the role of neuroimaging (MRI and FDG PET) in early diagnosis. They highlight MRI for identifying crucial patterns and FDG PET for detecting metabolic changes. Early detection is crucial for future treatments. Connectomics, studying brain networks, aids in predicting FTD progression. Emerging PET tracers, like UCBJ, show promise for early neurodegeneration markers. The episode is a valuable resource for neurologists interested in FTD diagnostics and monitoring.

Moderator: Youssuf Saleh (Oxford, United Kingdom)

Guest: Sebastiaan Engelborghs (Brussel, Belgium)

Youssuf Saleh interviews Prof. Sebastiaan Engelborghs on Alzheimer's biomarkers, focusing on amyloid and tau. They discuss diagnostic challenges, the need for prognostic markers, and potential serum markers like neurofilament light. Engelborghs highlights Alzheimer's complexity and the role of omics studies in patient subpopulations. The interview concludes with optimism for blood-based biomarkers revolutionizing diagnosis in the next five years, contingent on clinical validation and evolving therapies.

Moderator: Svetlana Tomic (Osijek, Croatia)

Guest: Veronica Cabreira (Edinburgh, United Kingdom)

In this episode of eanCast, Prof. Svetlana Tomic and Dr. Veronica Cabreira delve into the definition functional cognitive impairment. This disorder, affecting a significant number of patients at memory clinics, is marked by severe attention and concentration issues, and excessive self-monitoring of cognitive performance. Diagnosis hinges on cognitive symptoms, distress, and internal inconsistency. Treatments range from explaining the diagnosis to cognitive restructuring, cognitive behavioral therapy, and managing comorbidities.

Moderator: Federica Montagnese (Munich, Germany)

Guest: John Vissing (Copenhagen, Denmark)

In this week's episode, Federica Montagnese hosts Professor John Vissing as they delve into the intricate world of diagnosing muscular dystrophies. The discussion revolves around the crucial role of neuromuscular examinations and the significance of medical history, including school performance. Specific signs like myotonia and facial signs are explored, alongside the evolving landscape of genetic testing, advanced imaging techniques (MRI and ultrasound), and the potential of artificial intelligence in diagnostics. The speakers also touch on extra-muscular manifestations, expanding the understanding of these conditions.

Moderator: Gabriele Siciliano (Pisa, Italy)

Guest: Antonio Toscano (Messina, Italy)

Prof. Antonio Toscano is hosted by Prof. Gabriele Siciliano as he emphasizes the enduring significance of muscle biopsy in diagnosing neuromuscular disorders, particularly in cases of progressive muscle weakness. The episode stresses the need for a comprehensive diagnostic strategy, combining genetic testing with muscle biopsy, guided by clinical and imaging assessments. Overall, the episode underscores the continued importance of muscle biopsy for a thorough understanding of muscular dystrophies.

Moderator: Gabriele Siciliano (Pisa, Italy)

Guest: Tiziana Mongini (Torino, Italy)

In this episode, Prof. Gabriele Siciliano and Prof. Tiziana Mongini discuss a recent paper on Bag3 gene mutations linked to neurogenic distal muscle atrophy. They explore the evolving understanding of muscle dystrophies, the importance of genetic and molecular aspects, and challenges in diagnosis. Mongini underscores the significance of ancillary exams like neurophysiology and muscle MRI. They emphasize the complexity of genetic testing, advocating for a multidimensional approach involving clinical, genetic, and imaging data. Collaboration between basic and clinical researchers is stressed to comprehend neuromuscular complexities. The podcast concludes with a reminder to interpret genetic results cautiously and remain open-minded to diverse clinical presentations.

Moderator: Federica Montagnese (Munich, Germany)

Guest: Magda Mroczek (Basel, Switzerland)

In this podcast, Dr. Federica Montagnese interviews Dr. Magdalena Mroczek about gene mutations and variants in neuromuscular disorders, with a focus on muscular dystrophies. They discuss the impact of advanced technologies on genetic testing, highlighting the importance of clinical data and collaboration between clinicians and geneticists. The conversation touches on challenges in interpreting variants, the role of epigenetic factors, and initiatives to enhance access to genetic tools in low-income countries through international collaborations. The podcast underscores the dynamic nature of genetic diagnostics, emphasizing the importance of continuous research and education in the field.

Moderator: Barbara Tettenborn (St.Gallen, Switzerland)

Guest: Matthias Endres (Berlin, Germany)

In this episode, Barbara Tettenborn interviews Professor Matthias Endres, professor and chair of Neurology at the Charité Hospital in Berlin. The conversation delves into the connection between stroke and cardiology. Endres introduces the concept of stroke-induced atrial fibrillation, distinguishing it from pre-existing AF. They discuss the stroke heart syndrome, underlining the increased risk of cardiac events post-stroke. Troponin elevation is highlighted as a crucial biomarker, and the role of insular lesions in the brain in the syndrome is explored. The podcast concludes by emphasizing the importance of an interdisciplinary approach between neurology and cardiology for comprehensive patient care.

Moderator: Melinda Magyari (Copenhagen, Denmark)

Guest: Nikolaos Grigoriadis (Thessaloniki, Greece)

Follow Melinda Magyari and her guest Nikolaos Grigoriadis in the first MS episode of this month as they explore the Epstein-Barr Virus and its potential link to multiple sclerosis. They discuss how EBV might trigger or worsen MS, the challenges in confirming this connection, and implications for treatment and prevention. Other MS risk factors, such as genetics, environment, vitamin D levels, and lifestyle, are also covered.

Moderator: Benedetta Storti (Milan, Italy)

Guest: Anita Arsovska (Skopje, North Macedonia)

Benedetta Storti hosts Prof. Arsovska as they explore rare causes of strokes, covering conditions like cardiomyopathy, fibromuscular dysplasia, and immune-related factors. Arsovska stresses the significance of a comprehensive diagnostic approach, discussing specific features in tests and advocating for thorough investigations. The podcast addresses potential errors in diagnostic pathways and underscores the importance of biopsy in certain cases. Arsovska shares insights into tailored treatment options based on underlying conditions.

Moderator: Barbara Tettenborn (St. Gallen, Switzerland)

Guest: Thomas Meinel (Bern, Switzerland)

Thomas Meinel, a clinician scientist at the Burn Stroke Research Center in Switzerland, is hosted by Barbara Tettenborn as they discuss covert cerebrovascular disease. His research, particularly on strokes in patients on anticoagulation, is explored, highlighting the frequency and clinical implications of covert cerebrovascular lesions. Meinel emphasizes the current lack of clear evidence for managing these conditions. He also shares insights into ongoing studies that aim to connect epidemiological knowledge with clinical practices, encouraging neurologists to recognize and address covert cerebrovascular disease in patient care.

Moderator: Rolf Fronczek (Leiden, The Netherlands)

Guest: Matilde Leonardi (Milan, Italy)

Celebrate the end of the year with us with this special episode on Brain Health! Rolf Fronczek hosts Matilde Leonardi discussing her international neurology career and passion for Brain Health. She highlights the WHO Global Action Plan on epilepsy, stresses the increasing global burden of neurological diseases, and advocates for preventative measures. Leonardi details EAN's Brain Health Strategy, urging neurologists to advocate for brain health individually and nationally. Emphasizing a bio-psychosocial approach, she invites participation in EAN's leadership and advocacy training to contribute to shaping global brain health.

Moderator: Barbara Tettenborn (St. Gallen, Switzerland)

Guest: Didier Leys (Lille, France)

In this eanCast episode, Barbara Tettenborn interviews Didier Leys, Editor-in-Chief of the European Journal of Neurology, marking its 30th anniversary. Leys discusses the journal's evolution, challenges, and current impact factor of five. He outlines his daily editorial duties, stressing manuscript selection, ethical standards, and team management. Future plans include webinars, a history special issue, a virtual issue of top-cited articles, and video interviews with editors. He also encourages young researchers to submit, citing impact factor and submission delay importance. The episode closes with a glimpse into exciting 30th-anniversary initiatives.

Moderator: Johann Sellner (Mistelbach, Austria)

Guest: Tamuna Akhvlediani (Tbilisi, Georgia)

In this podcast episode, Prof. Johann Sellner interviews Prof. Tamuna Akhvlediani about the neurological aspects of new antiviral drugs for SARS-CoV-2. They discuss drugs like monoclonal antibodies, paxlovid, and remdesivir, emphasizing their mechanisms and potential applications beyond COVID-19. Prof. Akhvlediani details neurological side effects observed in trials and significant drug interactions, especially in chronic neurological patients. The episode closes with insights into managing these interactions in clinical practice.

Moderator: Johann Sellner (Mistelbach, Austria)

Guest: Tamuna Akhvlediani (Tbilisi, Georgia)

In this last episode on Infectious Diseases, Prof. Johann Sellner and Prof. Tamuna Akhvlediani explore nosocomial infections of the central nervous system (CNS). They cover the definition, common pathogens, and prevention methods like infection control and standardized surgery. Prof. Akhvlediani specifies prevalent CNS infections and addresses challenges in prevention and treatment, notably due to antimicrobial resistance. The conversation concludes with insights into treatment strategies, emphasizing the increasing challenge of antimicrobial resistance in healthcare-associated infections.

Moderator: Tamuna Akhvlediani (Tbilisi, Georgia)

Guest: Johann Sellner (Mistelbach, Austria)

In this week’s podcast hosted by Dr. Tamuna Akhvlediani, Prof. Johann Sellner discusses the connection between Epstein-Barr virus (EBV) and multiple sclerosis (MS). They explore the immune-mediated nature of MS, focusing on the impact of EBV and recent studies linking its infection to MS development. The episode delves into the controversies, hypotheses, and potential therapies related to EBV and MS, concluding with information on ongoing clinical trials and the influence of existing MS treatments on EBV.

Moderator: Tamuna Akhvlediani (Tbilisi, Georgia)

Guest: Johann Sellner (Mistelbach, Austria)

Dr. Tamuna Akhvlediani hosts Professor Johann Sellner in a podcast discussing the impact of COVID-19 on neuro infections. Professor Sellner covers global neuro infections, the decline during lockdowns, and the effectiveness of measures like face masks and vaccination. The episode emphasizes lessons learned, including insights into chronic neuro infection care disruptions and challenges, such as neuro-AIDS management during the pandemic. It concludes with findings from a study on how COVID-19 affected different neurological subspecialties.

Moderator: Yildiz Değirmenci (Istanbul, Turkey)

Guest: Antonio Farina (Florence, Italy)

This week, Dr. Yildiz Değirmenci and Dr. Antonio Farina discuss life-threatening neurological toxicities from immune checkpoint inhibitors. Dr. Farina highlights high fatality rates, long-term disabilities, and the urgency of early recognition and treatment. The episodeexplores management, including discontinuation and corticosteroids, and factors influencing outcomes. It touches on the association between adverse events and treatment response, resuming inhibitors, and stresses a multidisciplinary approach for informed decision-making. The conclusion emphasizes the importance of neurologists' awareness in addressing these rare yet significant neurological complications.

Moderator: Antonio Malvaso

Guest: Stefania Cuzzubbo

Dr. Antonio Malva hosts Dr. Stefania Cuzzubbo to discuss neurological complications from cancer immunotherapy. Dr. Cuzzubbo highlights immune-related adverse events, focusing on peripheral nervous system issues. The importance of early diagnosis using MRI, lumbar puncture, and nerve studies is emphasized. Treatment involves promptly stopping the drug and using steroids, with alternative therapies explored for steroid-refractory cases. Continued research in this evolving field is crucial.

Moderator: Anne Pavy-Le Traon (Toulouse, France)

Guests: Giovanna Calandra-Buonaura (Bologna, Italy) and Valeria Iodice (London, United Kingdom) 

In this week’s podcast episode Anne Pavy-Le Traon hosts two guests, Giovanna Calandra Buonaura and Valeria Iodice, as they discuss a hot topic related to Phenoconversion in Pure Autonomic Failure (PAF). They highlight the natural history of PAF and the importance of recognising this disease as a possible prodromal/ premotor phase of other alpha synucleinopathies. They discuss novel clinical and multimodal biomarkers in early diagnosis of these disorders.

Moderator: Antonio Malvaso (Pavia, Italy)

Guest: Alberto Vogrig (Udine, Italy)

In this episode of EAN Cast Weekly Neurology, Dr. Antonio Malvaso, a neurology resident, welcomes Dr. Alberto Vogrig, an international expert in the field of paraneoplastic neurological syndromes. They discuss the definition of these syndromes, emphasizing the causal relationship with cancer and their immune-mediated pathogenesis. They also talk about the revised diagnostic criteria and the importance of clinical diagnosis, laboratory techniques, and oncologic screening. The treatment for these syndromes includes immunosuppression, cancer therapy, and symptomatic treatment, tailored to the specific symptoms.

Moderator: Alberto Vogrig (Udine, Italy)

Guest: Giulia Berzero (Milan, Italy)

In this episode Dr. Alberto Vogrig is joined by Dr. Giulia Berzero to discuss the clinical approach to neurological symptoms in patients with cancer. She highlights the increasing occurrence of neurological complications in cancer patients due to improved survival rates and novel cancer treatments. Dr. Berzero emphasizes the importance of considering patient-related factors, tumor-related factors, and treatment modalities in assessing the risk of developing neurological symptoms. She also explains the signs that may prompt suspicion of brain metastasis and provides guidance on assessing and diagnosing CNS dissemination in cancer patients. Dr. Berzero stresses the need for a multidisciplinary approach and collaboration with oncologists to optimize patient care.

Moderator: Panagiotis Zis (Nicosia, Cyprus)

Guest: Peter Van den Bergh (Brussels, Belgium)

In this episode of the EAN Cast, Prof. Zis is joined by Prof. Van den Bergh to discuss the recently updated guidelines for diagnosing and treating Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP). The existing guidelines were last revised over a decade ago, and this new version aims to reflect the latest advancements in clinical and basic research. Prof. Van den Bergh highlights the common pitfalls in CIDP diagnosis and emphasizes the need for accurate diagnostic criteria.

The guidelines include flowcharts, tables, and criteria for different CIDP variants, as well as suggestions for supportive criteria to upgrade the diagnosis from possible CIDP to CIDP. The episode also delves into the treatment approaches, with an emphasis on corticosteroids, IVIG, and plasma exchange, and when to consider nerve biopsy.

Moderator: Thomas Berger (Vienna, Austria)

Guest: Wolfgang Grisold (Vienna, Austria)

In this podcast episode of EAN Cast, Professor Thomas Berger, Chair of the Department of Neurology at the Medical University in Vienna, and Professor Wolfgang Grisold, the current president of the World Federation of Neurology, discuss two important topics. First, they delve into the history and implementation of the World Health Organization's (WHO) Intersectoral Global Action Plan for epilepsy and other neurological disorders (ICAP). They emphasize that ICAP is a global effort to improve neurological services, and while epilepsy is a key focus, it covers various neurological disorders across countries, regardless of their income level. They highlight the importance of ICAP's five points: policy, treatment, prevention, research and innovation, and public health.

Secondly, they discuss the concept of brain health, a mission closely related to ICAP, and its importance. They mention the need to raise awareness, address stigma associated with neurological diseases, and work towards individualized care for patients. They stress that these initiatives require collaboration at all levels, from global organizations to individual neurologists.

Moderator: Yıldız Değirmenci (Istanbul, Turkey)

Guest: Panagiotis Zis (Nicosia, Cyprus)

In this podcast episode Dr. Yıldız Değirmenci is joined by Dr. Panagiotis Zis to discuss peripheral neuropathies. Dr. Panagiotis Zis explains that peripheral neuropathy refers to diseases or disorders of the peripheral nerves, including mono neuropathies affecting single nerves and poly neuropathies affecting multiple nerves. The clinical symptoms of peripheral neuropathy vary depending on the type and degree of nerve fiber involvement, with symptoms ranging from pain and abnormal sensations to motor issues like muscle atrophy and cramps.

Dr. Zis emphasizes the importance of a thorough neurological examination in diagnosing peripheral neuropathy and highlights key findings, such as reduced sensation, neuropathic pain, sensory ataxia, and reflex abnormalities. He also stresses the significance of electrophysiological studies, including nerve conduction studies, to confirm and classify neuropathies.

The episode touches upon the classification of neuropathies based on the temporal evolution of symptoms and the involvement of large or small nerve fibers. Dr. Zis emphasizes the need to identify the cause of neuropathies, especially in chronic cases, and discusses treatment options, both pharmacological and non-pharmacological, including dietary modifications for conditions like gluten neuropathy.