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Explore every episode of the podcast Core IM | Internal Medicine Podcast

Dive into the complete episode list for Core IM | Internal Medicine Podcast. Each episode is cataloged with detailed descriptions, making it easy to find and explore specific topics. Keep track of all episodes from your favorite podcast and never miss a moment of insightful content.

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1–50 of 229

TitlePub. DateDuration
#221 Colon Cancer Screening After Age 75 | 5 Pearls Segment Part 321 oct. 202600:17:06

ā€œShould you stop screening for colorectal cancer (CRC) at 75?ā€Ā 

This episode explores how to individualize screening decisions based on life expectancy, prior colonoscopy findings, and procedural risks. Learn how to navigate these nuanced conversations, avoid age-based assumptions, and use strategies like mailed FIT kits and offering screening choices to help more patients get screened.


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šŸ”¹Transcript and Show Notes

01:18 | Screening >75 yo?

10:06 | Takeaways on Colorectal Cancer Screening After 75Ā 

10:37 | Systems thinking: How do we get to an 80% screening rate


Tags: Core IM, Internal Medicine, Colorectal Cancer Screening, Gastroenterology, Cancer ScreeningĀ 



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#220 Colon Cancer Screening Nuances: 5 Pearls Segment Part 208 oct. 202600:21:09

ā€œWhat’s the best way to screen?ā€ This episode breaks down the pros, limitations, and follow-up needs of FIT, Cologuard, CT colonography, and colonoscopy to help you choose the right CRC screening option for your patients. Also learn practical colonoscopy surveillance intervals based on polyp size, number, and pathology.


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šŸ”¹Transcript and Show Notes

01:24 | Screening Options Besides Colonoscopy

11:22 | How FIT, FIT-DNA, and CT colonography differ and when each makes sense.

12:52 | Colonoscopy and Frequency

19:29 | How adenoma number, size, and histology guide surveillance intervals.Ā 


Tags: Core IM, Internal Medicine, Colorectal Cancer Screening, Gastroenterology, Cancer ScreeningĀ 



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#219 Updates in Triglycerides29 sept. 202600:33:31

ā€œThe triglycerides are high. Now what?ā€ This episode breaks down a practical approach to elevated TGs, from knowing when to check ApoB or non-HDL-C to choosing lifestyle changes, lipid-lowering medications, and when to suspect an underlying genetic disorder.Ā 


šŸ”¹Transcript and Show Notes

02:17 | Check a non-HDL-C or ApoB if TGs are ≄150 mg/dLĀ 

07:18 | Address waist circumference and lifestyle before meds for high TGs

10:52 | Dr. Watson’s 3-day carbohydrate responsiveness trialĀ 

17:07 | Order a fasting or nonfasting lipid panel?

19:00 | When do you reach for TG-lowering medications?Ā 

25:26 | Familial chylomicronemia syndrome (FCS)


Tags: CoreIM, Medical Education, Hypertriglyceridemia, ACC AHA lipid guidelines, lipid guidelines 2026, cardiovascular riskĀ 



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#218 Early-Onset Colon Cancer: 5 Pearls Segment Part 123 sept. 202600:15:20

ā€œToo young for colon cancer.ā€ This episode unpacks the red flags of early-onset colorectal cancer (CRC), from blood in the stool and iron deficiency anemia to persistent abdominal pain and changes in bowel habits, and offers practical pearls for closing the clinical loop. Also learn why a ā€œnegativeā€ family history may need a yearly refresh.


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šŸ”¹Transcript and Show Notes


01:45 | Colorectal cancer rising in younger adultsĀ 

06:42 | Why screening starts at age 45

08:15 | What may be driving early-onset colorectal cancerĀ 

13:37| Key takeaways: symptoms, follow-up, and family historyĀ 


Tags: Colorectal Cancer Screening, Internal Medicine, Gastroenterology, Cancer Screening, Oncology



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#217 Treatment for Alcohol Use Disorder: 5 Pearls Segment16 sept. 202600:37:37

ā€œIt didn’t work.ā€ This episode breaks down practical treatment options (dosing options for naltrexone, acamprosate, topiramate, gabapentin) and counseling pearls to help you meet patients where they are and support their recovery. Also discover blind spots in detox and rehab centers.

šŸ”¹Transcript and Show Notes

šŸ”¹ Explore ACP’s Substance Use Disorder Education Hub for videos and an AI-powered patient simulation to practice alcohol-use conversations: https://www.coreimpodcast.com/SUDhub

Alcohol Use and Chronic Health Conditions Mini Video Series

01:55 | #1: Naltrexone

12:06 | #2 Acamprosate

16:15 | #3: Topiramate

21:12 | #4: Other meds

29:31 | #5: Detox and rehab blind spotsĀ 


Tags: CoreIM, Medical Education, Addiction Medicine, Alcohol Withdrawal, Addiction Treatment, GLP-1, pharmacology



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#216 Clinician Grief: At the Beside Segment08 sept. 202600:39:59

Have you ever lost a patient and found yourself thinking about them long after the shift ended? This episode explores the grief clinicians can carry after a patient dies, including the losses that aren’t always obvious. We also discuss ways to work through that grief, recognize when it becomes complicated, and lean on your team for support.Ā Ā 


šŸ”¹Transcript and Shownotes

04:12 | What is Clinician Grief?

10:02 | Types of Losses

10:22 | Loss of a close relationship with a particular patient

12:56 | Loss due to a professional's identification with the pain of family members

13:56 | Loss of one's unmet goals and expectations and one's professional self-image and role

18:47 | Loss related to one's personal system of beliefs and assumptions about life

21:30 | Past unresolved losses or anticipated future losses

23:29 | The death of the self

25:44 | Coping


Tags: CoreIM, Medical Education, Clinician Wellbeing,Ā Burnout, Secondary Traumatic Stress, Complicated Grief, Coping With Grief, Medical humanities, medical ethics



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#215 Gallbladder & Biliary Testing: 5 Pearls Segment25 aoƻt 202600:34:34

How to choose between RUQ ultrasound, CT, HIDA, MRCP, EUS, and ERCP based on the clinical picture? When should you move from diagnostic imaging to therapeutic ERCP, and what should you know about sphincterotomy, stents, and stone removal? Plus, how to interpret bile duct dilation without jumping straight to obstruction?


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šŸ”¹Transcript and Shownotes


02:11 | Pearl 1: Gallbladder Problems Spectrum

07:33 | Pearl 2: Choose Imaging Strategically: Start with RUQUS, Escalate as Needed

14:34 | Pearl 3: Biliary Tree Diagnostics

19:19 | Pearl 4: Invasives that are Diagnostic and Therapeutic

27:06 | Pearl 5: Stenting in ERCP


Tags: CoreIM, Internal Medicine, Medical Education, Gallstones, Cholecystitis, Biliary Disease, ERCP, Biliary Imaging



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#214 Hyponatremia Management: A Core IM Classic12 aoƻt 202600:44:57

Throwback: Should you really fluid-restrict every patient with SIADH? When can IV fluids make hyponatremia better or worse? Are salt tabs actually doing enough? And what can urine studies tell you before you start treatment? Join us for a practical, physiology-driven approach to hyponatremia management, from fluids and solutes to loop diuretics and identifying the underlying cause.Ā 


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šŸ”¹Transcript and Shownotes


6:46 | Pearl 1: Key Principles

15:13 | Pearl 2: Fluids in hyponatremia

26: 03 | Pearl 3: Solutes in hyponatremia management

35:49 | Pearl 4: Lasix in hyponatremia management

40:05 | Pearl 5: Etiologies


Tags: CoreIM, Internal Medicine, Medical Education, SIADH, Fluid Restriction, Nephrology, Hospital Medicine, Urine Osmolality



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#213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series28 juil. 202600:32:59

Why can lower-dose combinations be more effective and better tolerated than maximizing one medication? How to troubleshoot common challenges such as amlodipine edema, gout, electrolyte abnormalities, and the patient who says they cannot tolerate anything? Why ACT (ARBs, Calcium Channel Blockers, Thiazides) is the preferred first-line framework, and how to personalize medication choices based on comorbidities and side effects.


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šŸ”¹Transcript and Shownotes


03:00 | Diagnosing HypertensionĀ 

04:10 | When to Start Combination Therapy Instead of MonotherapyĀ 

07:00 | Choosing First-Line Therapy Using the ACT FrameworkĀ 

13:23 | Why ARBs Are Often Preferred Over ACE InhibitorsĀ 

16:02 | Choosing the Right ARB: Candesartan vs LosartanĀ 

18:39 | Comparing Potency & Duration Across First-Line AntihypertensivesĀ 

20:54 | Amlodipine Edema: Why It Happens and How to Fix ItĀ 

23:54 | Thiazides: Practical Tips, Electrolyte Problems & Class-Killer Side EffectsĀ 

29:33 | Managing Patients Who 'Can't Tolerate' Blood Pressure MedicationsĀ 


Tags: Hypertension Management, High Blood Pressure, Primary Care, Internal Medicine, Core IM



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#212 Top 10 Highlights of the New Lipid Guidelines15 juil. 202600:23:52

Learn from primary care docs what has been practiced and changed from the 2026 ACC/AHA Lipid Guidelines! Learn how the new CPR framework (Calculate, Personalize, Reclassify) and PREVENT risk calculator change statin decisions, why LDL targets are back, and when to use Lp(a), ApoB, and coronary artery calcium (CAC) testing. Discover updated risk-enhancing factors, expanded indications for non-statin therapies, and practical strategies to personalize lipid management for both primary and secondary


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šŸ”¹Transcript and Shownotes:Ā Ā 

01:17 | Highlight #1 & #2: CPR and PREVENT Score

03:14 | Highlight #3: Updated ASCVD Risk Categories Using the PREVENT Score

05:30 | Highlight #4: LDL Targets Are Back

07:20 | Highlight #5: High-Risk Conditions That Bypass the PREVENT Score

08:41 | Highlight #6: Lp(a) Screening for Everyone

11:51 | Highlight #7: When to Use ApoB Testing

13:16 | Highlight #8: Reproductive Risk Factors

15:29 | Highlight #9: Using CAC to Guide Statin Therapy

19:09 | Highlight #10: Non-Statin Therapies


Tags: CoreIM, Internal Medicine, Medical Education, Cholesterol, Statins, LDL, ASCVD, Preventive Cardiology, LpA, ApoB, CAC, ACC2026, Cardiology, PrimaryCareĀ 



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#211 Breaking Down MASLD vs. MASH and the MAESTRO-NASH & ESSENCE Trials: Beyond Journal Club Segment29 juin 202600:33:40

MASLD affects nearly one in three adults worldwide, yet many patients remain undiagnosed until advanced fibrosis or cirrhosis develops. So, which patients should clinicians actually be screening? When is a FIB-4 enough, and when should we move to elastography or hepatology referral? And are we finally entering an era where we can meaningfully treat MASH?

In this Beyond Journal Club episode, we unpack the evolving language of steatotic liver disease and take a close look at two major trials: MAESTRO-NASH studying resmetirom, the first FDA-approved liver-directed therapy for MASH,Ā and ESSENCE, evaluating semaglutide in biopsy-confirmed disease.

Along the way, we explore what these biopsy-based histologic endpoints really mean, why placebo responses were surprisingly high, and whether improvements in steatohepatitis and fibrosis will ultimately translate into better clinical outcomes for patients.

This episode is for clinicians trying to understand where the field is headed, which patients deserve closer attention, and how metabolic liver disease is increasingly becoming part of everyday primary care and hospital medicine.


šŸ”¹Sponsor:Ā Oakstone CME

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šŸ”¹Transcript and Shownotes: Ā 

01:57 | Understanding MASLD as a Systemic DiseaseĀ 

05:45 | MASLD vs MASH vs Met-ALD: Spectrum Steatotic Liver DiseaseĀ 

08:55 | How to Screen for Fibrosis (FIB-4 & FibroScan)Ā 

16:15 | Lifestyle Treatment & Weight Loss TargetsĀ 

19:00 | ESSENCE Trial: Semaglutide for MASHĀ 

21:58 |Ā MAESTRO-NASH Trial: ResmetiromĀ 

27:27 | Future Treatments for MASHĀ 

30:51 | Key Takeaways for CliniciansĀ 


Tags: CoreIM, Internal Medicine, Medical Education, Hepatology, Fatty Liver Disease, Metabolic Dysfunction Associated Steatohepatitis, Nonalcoholic Fatty Liver Disease, Liver Fibrosis



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#210 HTN in Dialysis: 5 Pearls Segment17 juin 202600:25:39

What blood pressure should we target in patients on hemodialysis? Why volume control remains the foundation of treatment? How blood pressure targets differ from the general population. Learn practical pearls on medication timing around dialysis, drug dialyzability, antihypertensive selection, and strategies to prevent intradialytic complications while optimizing long-term outcomes.Ā 


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šŸ”¹Transcript and Shownotes: Ā 

02: 19 | Pearl 1: Blood Pressure TargetsĀ 

09: 40 | Pearl 2: Timing Medications and DialyzabilityĀ 

15: 31 | Pearl 3 - Pharmacologic Management Nuances in Dialysis PatientsĀ 

22: 57 | Putting It All Together: The Medication HierarchyĀ 


Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, ESRD, End-Stage Kidney Disease, Hypertension, Kidney Health, Dry Weight, Volume Overload



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#209 Dialysis and Fluid Management: 5 Pearls Segment10 juin 202600:31:54

Why is fluid management the most important part of dialysis care? This episode explores the fundamentals of hemodialysis, why ESKD patients have unique physiology, and how volume overload, not just hypertension, drives many complications. Learn practical pearls on dry weight, sodium restriction, diuretics, and the strategies that can reduce hospitalizations and improve patient outcomes.Ā 


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šŸ”¹Transcript and Shownotes: Ā 

02:49 | Pearl 1: Foundations of Dialysis

09:21 | Pearl 2: Distinct Physiology

11:42 | Pearl 3:Ā Why is fluid management so important?

19:43 | Pearl 4: Fluid Management Pro-tips

25:31 | Pearl 5: Diuretics in Patients with Residual Kidney Function


Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, Dialysis, End-stage kidney disease, Hypertension, Kidney Health, Dry Weight, Volume Overload



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#208 AI vs. Human with Post-Op AFib: Bread & Butter Series27 mai 202600:29:19

Can AI manage post-op atrial fibrillation or does medicine still require human judgment? Using post-op AFib as a case study, we explore where algorithms help, where evidence falls short, and why clinical context still matters. When evidence is incomplete, and every patient is different, can AI truly practice medicine or only assist the clinicians who do? This episode explores the space between algorithms, uncertainty, and human judgment in modern medical care.Ā 


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šŸ”¹Transcript and Shownotes: Ā 

02:51 | Broad workup for reversible causes and other etiologies of AFib that may occur post-op

05:10 | Considerations forĀ management of post-op atrial fibrillation

13:00 | Stroke risk in atrial fibrillation

20:49 | Outpatient management of atrial fibrillationĀ 

25:54 | The role of AI in medical decision-making


Tags: CoreIM, Internal Medicine, Medical Education, Atrial Fibrillation, Cardiology, Open Evidence



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#207 Is There a Doctor on Board? In-Flight Emergencies18 mai 202600:27:49

We start with a gripping story of seizures and use it as a jumping-off point to unpack practical pearls for in-flight emergencies. Along the way: what’s actually in the emergency medical kit, when planes divert, how ground medical support works, altitude physiology, legal protections, and how to stay calm when medicine suddenly happens at 35,000 feet. By the end, you may still sweat a little…but hopefully less than before.

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šŸ”¹Transcript and Shownotes: Ā 


04:40 | Emergency Medical Kit (EMK) Standard Contents

08:50 | Role of Ground-Based Medical Support & Flight Diversion Decision-Making

19:35 | Interpreting Hypoxia at Altitude

22:06 | In-Flight Liability

23:35 | Common Chief Concerns & Useful Additional Medications

24:53 | How to Be Resourceful in an Austere Environment


Tags: CoreIM, Internal Medicine, Medical Education,Ā In-flight Care, Medical Emergencies, Clinical Reasoning, Seizure Management, Hypoxia, Airway Management, Cardiac Emergency, Syncope, Respiratory Distress



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#206 Eosinophilia: 5 Pearls Segment28 avr. 202600:43:13

Can you distinguish benign eosinophilia from a sign of serious disease, and know exactly when to act at the bedside?

In this high-yield episode, test your clinical reasoning as we tackle:

  • When eosinophilia becomes dangerous and why it matters
  • How to distinguish if its from atopy vs. systemic disease
  • Which medications to stop (and which to watch)
  • How travel, diet, and exposure history shape your workup
  • When to suspect malignancy before giving steroids


šŸ”¹Transcript and Shownotes:Ā 

02:34 | Why Do We Care About Eosinophilia? (Pearl 1)

10:24 | Atopy and Eosinophilia (Pearl 2)

18:57 | Drugs and Eosinophilia (Pearl 3)

27:29 | ID and Eosinophilia (Pearl 4)

33:54 | Pearl 5: Eosinophilia, Steroids, and Neoplasms (Pearl 5)


Tags: CoreIM, Internal Medicine, Medical Education, Eosinophilia, Hypereosinophilia, Allergy Immunology, Hematology, Pulmonology, Parasitic Infections, Atopy



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#205 Nutrition Studies, Coffee and the CRAVE Trial: Beyond Journal Club with the NEJM Group15 avr. 202600:32:15

Is coffee helping or harming our patients’ hearts?

In this Beyond Journal Club, we unpack theĀ CRAVE trialĀ and use it as a lens to answer a bigger question:

How should clinicians interpret nutrition research, especially when it feels inconsistent or hard to trust?

Listen for a concise, practical framework you can use the next time a patient asks about coffee, diet, or lifestyle.


šŸ”¹Sponsor: Oakstone CME

Use the code "CORE25" for 25% off:Ā https://www.coreimpodcast.com/MKSAPĀ 

šŸ”¹Ā Transcript and Show notes

00:00 | Challenges of interpreting nutritional research.

02:22 | Best practices for evaluating studies in nutrition.Ā 

12:35 | Delve into the CRAVE trial as an example of critically appraising nutritional investigations.

26:41 | Applying this to clinical practice for your patients.


Tags:Ā IMCore, Internal Medicine, Medical Education, Epidemiology, Diet and Lifestyle



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#204 Diabetic Foot Infections & Osteomyelitis: 5 Pearls Segment01 avr. 202600:33:30

Why can these infections be tricky? How to diagnose osteomyelitis at the bedside? Do we always need IV vs oral antibiotics? And the best for last: Simple, practical wound care strategies for medical students, residents, and clinicians who want a clear, usable approach.


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šŸ”¹Transcript and Shownotes:

02:15 | Pearl 1: Pathophysiology

08:20 | Pearl 2: Diagnosis

16:35 | Pearl 3: Treatment

20:35 | Pearl 4: Antibiotics

27:39 | Pearl 5: Wound Care


Tags:Ā CoreIM, Internal Medicine, Medical Education, Diabetic Foot Infections, Osteomyelitis, Foot Ulcer, Wound Care



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#203 POCUS for AKI & Dialysis | Real Cases That Changed Management23 mars 202600:29:19

A dialysis patient with a chronic cough: is it COPD, or are they still volume overloaded?

A patient with AKI and hyperkalemia says they’re still peeing — does that rule out post-obstructive AKI?

A patient arrives in the ED with uremic symptoms and a newly created AV fistula. Can you safely use it, or do you need to place a temporary dialysis catheter?

And the classic inpatient dilemma: your heart failure patient looks better after diuresis, but the creatinine is rising. Is it time to stop, or should you keep going?


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šŸ”¹Transcript and Shownotes:


00:52 | What is NephMadness?

02:19 | Detecting post-renal obstruction in a patient who reported normal urination

11:26 | POCUS for discharge or continue diurese

17:25 | Distinguishing COPD from volume overload in a dialysis patient using lung ultrasound

23:55 | Assessing AV fistula maturity at the bedside to potentially avoid placing a temporary dialysis line


Along the way, we discuss practical ways clinicians can use renal, lung, and venous ultrasound to clarify uncertain clinical situations and make faster decisions at the bedside.


If you’ve ever paused on rounds, wondering ā€œwhat should we do next?ā€ in a patient with kidney disease, this episode explores how POCUS can help answer that question.


Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, AKI Management,Ā POCUS



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#202 Dementia Part 2: Gray Matters Segment12 mars 202600:47:16

Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help. In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them.

• Do cholinesterase inhibitors really work?

• What should clinicians know about lecanemab and donanemab before referring patients?

• How much benefit should we expect and for how long?

• When should you deprescribe dementia medications?


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šŸ”¹Transcript and Shownotes

02:27 | Deep Dive 1: How do we deliver the news of a diagnosis of dementia?

09:41 | Deep Dive 2: Prescribing medications for cognitive decline

29:30 | Deep Dive 3: Patient-centered management for a patient with cognitive decline

35:46 |ā€ŠDeep Dive 4: Planning for an uncertain future


Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant



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#201: Dementia Part 1: Gray Matters Segment25 fƩvr. 202600:46:27

Cognitive decline is tough for all parties. What are the high-yield questions to ask? What should you add to your one-liner? When do you stop using MOCA and try to clearly describe their functional status? Do all patients with cognitive decline need an MRI?


šŸ”¹Sponsor: DoxGPT by Doximity - an AI assistant built with practicing clinicians to deliver bottom-line clinical answers, chart summaries, secure calls, and faxing directly inside the Doximity app. See how fast it is and how easy to read at DoxGPT.com


šŸ”¹Transcript & Shownotes:


01:12 | Cognitive Concerns During a Routine Follow-Up

03:41 | Deep Dive 1: How do you pivot when you recognize unexpected memory issues?

15:08 | Deep Dive 2: What tools should we use to characterize and stage cognitive decline?

31:09 | Deep Dive 3: How do we determine the etiology of cognitive decline?


Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant



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#200: Insulin and QWINT-1 Trial in T2DM: Beyond Journal Club Segment with NEJM Group11 fƩvr. 202600:28:14

From metformin to basal insulin to overlooked older medications, this episode reviews the T2D medication toolkit clinicians use every day. We then dive into new evidence on once-weekly insulin to help you individualize therapy while reducing treatment burden.


šŸ”¹Ā Sponsor:Ā Pain Management and Opioids Adaptive Learning Free Online Course by NEJM Group:Ā https://cme-info.nejm.org/core-im/


šŸ”¹Transcript and Shownotes:

00.58 | Insulin Hx & Types

06:00 | Indications for Insulin and the Burden on Patients

08:26 | What is the QWINT-1 Trial?

16:18 | Discussion


Tags: CoreIM, Internal Medicine, Evidence-Based Medicine, Insulin Resistance, Clinical Reasoning, Hospital Medicine, Medical Education, Endocrine, Endocrinology



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#199 Privacy & Confidentiality: At the Bedside Segment28 janv. 202600:37:45

Is patient confidentiality absolute or conditional? When does protecting privacy put others at risk? Can you follow a former patient in the EHR for learning? Should you post a compelling case online even if it’s ā€œde-identifiedā€? And when does the law force you to betray patient trust? In this episode of At the Bedside, learn how clinicians should act when ethics, law, and trust collide.


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šŸ”¹Transcript and Shownotes:

03:51 | What is the difference between Privacy and Confidentiality?

05:50 | Guidelines and laws

10:06 | Limits/appropriate breaches (competing principles/obligations)Ā 

22:03 | Privacy vs education

35:34 |Ā Conclusion



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#198 Microskills for Change That are Big Enough to Matter, Small Enough to Win21 janv. 202600:28:49

Baby alligatorsĀ Ā - those betrayals of purposeĀ , or, death by a thousand paper cutsĀ !

Check out our latest episode, where Dr. Eileen Barrett walks us through how toĀ tackle baby alligators with:

Regulated curiosity

Strategic empathy

Small, well-chosen moves...

...and change that isĀ big enough to matter, and small enough to win!


šŸ”¹ Sponsor:Ā Caraway’s cookware set is a favorite for a reason.

For 10% off, go toĀ Carawayhome.com/CoreIMĀ or use codeĀ CoreIMĀ at checkout.


šŸ”¹ Transcript & Shownotes

00:00 | What are ā€œbaby alligatorsā€ in medicine?

02:24 | Rifaximin & Workflow Fixes

14:17 | Verbal Orders Policy

18:39 | Micro Skills for Change

25:12 | KeyĀ Takeaways


#PhysicianBurnout #DoctorLife #HealthcareEfficiency, CoreIM, Internal Medicine, Career Development, Quality Improvement, QI



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#197 Hypercoagulability Part 2: 5 Pearls Segment07 janv. 202600:38:26

Gray zones of VTE management! How to approach anticoagulation duration in unprovoked, provoked-irreversible, and provoked-reversible clots?

When dose-reduced DOACs make sense for long-term secondary prevention? What truly constitutes DOAC failure? We also devle into how APLAS a critical do-not-miss diagnosis that changes management entirely.


šŸ”¹ Sponsor:Ā Pain Management and Opioids Adaptive Learning Free Online Course by NEJM Group: https://cme-info.nejm.org/core-im/

šŸ”¹ Transcript & Shownotes

(2:56) - (13:15)Ā | PEARL 1: Managing clots in the ā€œunprovokedā€/provoked-irreversible patient

(13:21) - (18:10) |Ā PEARL 2: Managing provoked,Ā ā€œreversibleā€ clots

(18:14) - (25:14) | PEARL 3: DOAC failure: time to step it up?

(25:20) - (37:25) | PEARL 4: APLAS: the exception to everything


Tags: CoreIM, Internal Medicine, ClinicalPearls, Medical Education, IMCore, hospitalist, physician assistant, nurse practitioner, medical student, internal medicine, hematology



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#196 Stories of Courage and Career Development with Horn Award17 dƩc. 202500:19:13

We hope these stories resonate with anyone who has felt pulled between professional purpose and personal life, and remind you that you’re not alone in wanting both.

šŸ”¹Ā Sponsor: Oakstone CME

Use the code "CORE30" for 30% off:Ā https://www.coreimpodcast.com/MKSAPĀ 

šŸ”¹Ā Transcript and Shownotes

(1:09) | How the Horn Award Opened the Door to Growth in Dr. Tyra Fainstad’s Career and Life

(10:28) | How Dr. Carol Ward Created the Horn Award and Honored Mary Horn’s Legacy

(14:16) | Dr. Hilit Mechaber’s Story of Courage, Vision, and Impact Beyond the Award

(17:55) | Why does the Horn Award Matter?

Tags:Ā CoreIM, Internal Medicine, Career Development Award,Ā Mary O'Flaherty Horn Award, Clinical Care, Scholarship, Teaching, Leadership, Wellness and Care, Family Responsibilities



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#195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group10 dƩc. 202500:21:44

Antibiotic duration for bacteremia is something most of us learned by habit, not by trial data. In this episode, we walk through the BALANCE trial and use it as a lens to revisit how 1) host, 2) organism, and 3) source should guide treatment. When shorter really is enough, and when it isn’t?

šŸ”¹Ā Sponsor: Oakstone CME

Use the code "CORE30" for 30% off:Ā https://www.coreimpodcast.com/MKSAPĀ 

šŸ”¹Ā Transcript and Shownotes

Timestamp

(02:58) | Host, Organism, Source: The Core Framework Behind Duration

(09:02) | How Evidence Shifted Practice

(11:27) | The BALANCE Trial: Short-Course vs Standard-Course Therapy

(18:55) | Where does this leave us?


Tags: CoreIM, Internal Medicine, Infectious disease, Evidence-Based Medicine, Clinical Reasoning, Hospital Medicine, Medical Education



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#194: Severe Hypertriglyceridemia: 5 Pearls Segment03 dƩc. 202500:38:20

How quickly can triglycerides rise? At what threshold are patients at risk of pancreatitis or cardiovascular adverse outcomes? What do you have to rule out? How do you counsel on lifestyle changes? Which medications do you start with why and when?

šŸ”¹ Transcript and Shownotes

(03:19) | Lipoprotein Lipase and Why Triglycerides Fluctuate Fast

(05:27) | Triglycerides as a Cardiovascular Risk Marker

(09:28) | Acute Management For Pancreatitis induced by Triglycerides

(14:34) | Lifestyle Counseling

(17:31) | Medications That Lower Triglycerides

(25:29) | How to Choose the Right Triglyceride Therapy

(27:56) | Genetic Causes and When to Suspect Familial Disorders


Tags: CoreIM, Internal Medicine, Lipidology, lipid, Cardiology, Metabolic Health, Triglycerides, Evidence-Based Medicine, Clinical Reasoning, Hospital Medicine, Medical Education, primary care



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#193 Venous Congestion & VEXUS Interview with Dr. Ross Prager19 nov. 202500:34:44

Why is venous congestion not the same as volume overload? How can looking at IVC as well as doppler on the hepatic vein, portal vein, and/or intrarenal vein help? Can venous congestion explain someone's delirium? Or be at play in septic shock? What are the limitations of the VEXUS score?


šŸ”¹ Sponsor: Oakstone CME

Use the code "CORE30" for 30% off: https://www.coreimpodcast.com/MKSAPĀ 


šŸ”¹Transcript and Shownotes


(00:00) | Volume overload vs. Venous Congestion

(05:49) | Venous Congestion and AKI, mortality, possible delirium

(10:10) | Measuring Venous Congestion and the Role of VEXUS

(15:05) | Common Mistakes and Best Practices of VEXUS score

(23:13) | Assessing Fluid Tolerance and Risks with Venous Doppler in Acute Care

(25:29) | Fluid vs. Vasopressor Strategy Guided by Venous AssessmentĀ 



Tags: CoreIM, Internal Medicine, Critical Care, Nephrology, Cardiology, Fluid Management, POCUS, Ultrasound, Doppler, Hospital Medicine, Clinical Reasoning, Medical Education



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#192 Debate on First-Line Medications for Diabetes05 nov. 202500:36:50

SGLT-2i vs. GLP-1? vs Metformin? How do you balance the cost and coverage of first-line options like metformin, SGLT-2, and GLP-1s? How do you choose between SGLT-2 and GLP-1s for comorbidities like CAD or CKD? And how do you weigh their side effects and practical use?

šŸ”¹ Sponsor:

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šŸ”¹ Transcript and Show Notes

Timestamps:

(01:43) | Case 1: Managing Uncontrolled Diabetes in a 47-Year-Old Male

(07:15) | Understanding Cost and Insurance Barriers in Diabetes Care

(09:26) | Case 2: Addressing Weight Gain and Financial Stress in a 52-Year-Old Male

(14:16) | Case 3: Managing Coronary Artery Disease and CKD in a 66-Year-Old Male

(19:41) | Case 4: Severe Obesity and Pain Management in a 59-Year-Old Female

(24:19) | Case 5: High A1C and Vascular Comorbidities in a 67-Year-Old Female

(35:34) | Weighing Side Effects and Practical Use of GLP-1 and SGLT2 Inhibitors


Tags: CoreIM, Primary Care, Endocrinology, Diabetes Mellitus, Type 2 Diabetes, Type 1 Diabetes, Metformin, GLP-1, SGLT2, Insulin, CGM, A1C, DKA, Medical Education, Clinical Reasoning, Hospital Medicine



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#191 Hepatorenal Syndrome Part 2 on Management: 5 Pearls Segment22 oct. 202500:30:34

What really works when treating HRS? Vasoconstrictors like terlipressin vs. norepinephrine vs. midodrine: how do we decide which to use? Do you give albumin? When do you give Lasix or another diuretic? When is the better choice transplant, dialysis, or even palliative care?

šŸ”¹Ā Sponsor:Ā Oakstone CME

Use the code "CORE25" for 25% off:Ā https://www.coreimpodcast.com/MKSAP

šŸ”¹Ā Transcript & Show Notes

Timestamps:

Ā (00:12) | Introduction and Overview of Hepatorenal Treatment

Ā (03:38) | Vasoconstrictors Focus: Terlipressin, Norepinephrine, and Midodrine

Ā (12:32) | Finding the Right Dose of Albumin and Knowing When to Stop

Ā (15:06) | Volume Management: Balancing MAP, Diuretics, and Creatinine

Ā (21:42) | Understanding the High Mortality of HRS-AKI

Ā (32:30) | Transplant, Dialysis, or Palliation Care


Tags: CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Hepatorenal Syndrome, HRS-AKI, Cirrhosis, Nephrology, Liver Disease



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#190: Hepatorenal Syndrome Part 1: 5 Pearls Segment15 oct. 202500:36:11

HRS-AKI vs. other causes of AKI in cirrhosis: What do serum or urine sodium clues, albumin challenges, and shifting diagnostic criteria actually reveal about getting the diagnosis right?

šŸ”¹Ā Sponsor:Ā Oakstone CME

Use the code "CORE25" for 25% off:Ā https://www.coreimpodcast.com/MKSAP

šŸ”¹Ā Transcript & Show Notes

Timestamps:

Ā (00:57) | Understanding the Pathophysiology of HRS

Ā (03:42) | How Portal Hypertension Traps the Kidneys

Ā (10:32) | Sorting the Differential of AKI in Cirrhosis Beyond HRS

Ā (18:28) | Hyponatremia and Urine Sodium in Advanced Cirrhosis

Ā (24:04) | Official Diagnosis and Evolving Criteria of HRS

Ā (29:30) | Albumin: When It Helps and When to Hold Back

Ā (34:00) | Recap and Future Directions


Tags: CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Nephrology, renal, hepatology, Portal Hypertension, Liver Disease



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#189 Bisphosphonates and Fracture Prevention Trial: Beyond Journal Club with NEJM Group01 oct. 202500:30:50

Who’s really at risk for fractures, and how should we be treating them?Ā 

Most fragility fractures occur in patients without osteoporosis. Should we rethink who gets treated? And could just one or two IV infusions (spread years apart) of zoledronate prevent fractures for years? Have the concerns about bisphosphonates been overblown?

Find out all the nuances on this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.


šŸ”¹Ā Sponsor:Ā Oakstone CME

Use the code "CORE25" for 25% off:Ā https://www.coreimpodcast.com/MKSAP

šŸ”¹Ā Transcript & Show Notes

Timestamps:

(00:59) | Diagnosing Osteoporosis and Hidden Fracture Risk

(05:38) | Evolution of Bisphosphonate Use in Osteoporosis Treatment

(07:51) | Current Use of Bisphosphonates: Benefits, Risks, and Side Effects

(10:31) | Exploring Non-Bisphosphonate Options for Fracture Prevention

(11:44) | Teriparatide and Alternative Osteoporosis Medications

(14:53) | Inside the Latest Bisphosphonate Clinical Trial

(18:07) | Key Findings from the Zoledronate Fracture Prevention Study

(22:38) | Public Health Impact of Fracture Prevention Strategies

(24:24) | Final Takeaways and Expert Perspectives on Osteoporosis Care


Tags:Ā Ā CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Osteoporosis, Fragility Fractures, Zoledronate, Bone Health



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#188 Orthostatic Hypotension Part 2: Gray Matters Segment22 sept. 202500:35:35

Medications for orthostatic hypotension! When to initiate treatment, how to use them safely, and what to do when new issues arise during treatment. How do those change if someone has autonomic failure? What do you do when your patient has hypertension AND also has orthostatic hypotension?

šŸ”¹Ā Sponsor:Ā Oakstone CME’

Use the code "CORE25" for 25% off:Ā https://www.coreimpodcast.com/MKSAP

šŸ”¹ Transcript & Show Notes

Timestamps (+/- 1-2 mins):

(00:28) | Case Recap: Beyond Non-Pharm Strategies

(03:07) | Midodrine: Timing, Testing, & Supine Hypertension

(06:23) | Fludrocortisone: Benefits vs. Risks

(09:01) | Droxidopa: Evidence, Side Effects, Access Issues

(10:11) | Pyridostigmine & NSAIDs: Secondary Options

(12:31) | Balancing Hypertension and Orthostatic Hypotension

(14:29) | Functional Hypotension & Risk Stratification

(18:45) | Symptomatic Patients: What to Stop, What to Continue

(20:19) | Autonomic Disease: Supine & Nocturnal Hypertension

(21:47) | Bed Elevation, Compression, & Non-Pharm Pearls

Tags: Internal Medicine, Geriatrics, Autonomic Dysfunction, Hypertension, Syncope, Falls, Patient Safety, Medical Education, physician assistant, nurse practitioner, hospitalist, primary care, neurology



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#187 Orthostatic Hypotension Part 1: Gray Matters Segment11 sept. 202500:37:20

Learn specific, practical ways to counsel patients on non-pharmacologic interventions. What is our goal with OH treatment? Is it the blood pressure number that matters? How do we avoid missing neurogenic causes of orthostatic hypotension (OH)?Ā 

šŸ”¹Ā Sponsor:Ā Oakstone CME’

Use the code "CORE30" for 30% off effective 11/1/25 through 1/31/26:Ā https://www.coreimpodcast.com/MKSAP

šŸ”¹Ā Transcript & Show Notes

Timestamps:

(00:05) | Case Presentation: Urinary Retention → Lightheadedness

(02:37) | Defining Orthostatic Hypotension & Prevalence

(04:10) | Why Diagnosis Is Harder Than It Seems

(06:20) | How (and When) to Measure Orthostatic Vitals

(10:06) | Role of Heart Rate in Narrowing the Differential

(14:41) | Rethinking Treatment Goals: Function > Numbers

(17:52) | Recognizing Orthostatic Intolerance Symptoms

(22:14) | Non-Pharmacologic Strategies in the Hospital

Tags: Primary care, Internal Medicine, Physician Assistant, Nurse Practitioner, Geriatrics, Autonomic Dysfunction, Syncope, Falls, Patient Safety, Medical Education



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#186 Pneumothorax: 5 Pearls Segment25 aoƻt 202500:37:03

Next time you’re squinting at a chest tube, feel confident you know exactly what to look for and why. Hear it explained in a way that really sticks!

šŸ”¹Ā Sponsor:Ā Oakstone CME’s ACP MKSAP Audio Companion

Use the code "CORE30" for 30% off effective 11/1/25 through 1/31/26:Ā https://www.coreimpodcast.com/MKSAP

šŸ”¹Ā Transcript & Show Notes

Timestamps:

(02:50) | Xray vs. POCUS vs. CT for Pneumothorax Diagnosis

(07:29) | Do All PTXs Need Chest Tubes?

(11:55) | Explaining Pneumothorax to Patients

(14:58) | Understanding the Pleural Drainage System

(26:11) | Monitoring Air Leaks with the Water Seal Chamber

(32:27) | Managing Persistent Air Leaks

Tags: CoreIM, Internal Medicine, Pulmonology, Critical Care, Medical Education, 3-Chamber Drainage System, Endobronchial Valves and Pleurodesis



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#185 Neutropenia: 5 Pearls Segment13 aoƻt 202500:42:21

How do you work up neutropenia? When is neutropenia benign? When do neutrophils recover? How can you diagnose neutropenic fever in the first 15 minutes and start antibiotics in the first 60 minutes? Do you always add MRSA coverages? Only Pseudomonas coverage? When do you add fungal coverage?

šŸ”¹ Sponsor:Ā Oakstone CME’s ACP MKSAP Audio Companion

Use the code "CORE30" for 30% off effective 11/1/25 through 1/31/26:Ā https://www.coreimpodcast.com/MKSAP

šŸ”¹ Transcript & Show Notes


Timestamps:

(02:24) | Approach to Neutropenia & Duffy Null

(11:38) | Dose and duration-dependent neutropenia vs. immune-mediated neutropenia

(19:46) | When do neutrophils recover?

(29:56) | Classifying Neutropenic Fever Syndromes

(29:53) | Strategies for Managing Low-Risk Neutropenic Fever

(33:02) | Antimicrobial Therapy and Duration in Febrile Neutropenia


Tags: CoreIM, Internal Medicine, Oncology, Hematology, Medical Education, Physician Assistant, Nurse Practitioner, Neutropenic Fever Management, Antibiotics



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#184 Stories for the Feels28 juil. 202500:10:44

Have a good laugh and reflect deeply with these three stories that hit the feels in different ways.

If you'd love to hear more stories from Dr. Maria Rosasco, check out some of her other appearances on the podcast: July Stories and Handoffs & Contingency Planning.


šŸ”¹ Sponsor: Oakstone CME’s ACP MKSAP Audio Companion

Use the code "CORE30" for 30% off effective 11/1/25 through 1/31/26:Ā https://www.coreimpodcast.com/MKSAP

šŸ”¹Ā Transcript and Show Notes


Timestamps:

(01:04) | Story 1: Sharing a Personal Story for Patient Care

(03:42) | Story 2: Leading a Family Meeting

(06:52) | Story 3: Early Days of the COVID-19 Pandemic

(10:22) | What Rituals and Values Guide Your Path in Medicine


Tags:Ā CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Narrative Medicine, Humanities



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#183 Diagnose the Clinician: Hoofbeats Segment21 juil. 202500:33:11

What went wrong? What were the reasoning or contextual missteps that led us astray?

šŸ”¹Ā Sponsor:Ā NEJM Fellowship Program, clickĀ here to learn more and/or apply! Due Aug 1, 2025

šŸ”¹ Transcript and Show Notes

Timestamps:

(00:02) | Case Presentation and Initial Diagnosis

(02:47) | Tachycardia and Early Impressions

(04:10) | Clinical Deterioration and New Clues

(07:19) | Problem Representation and Reflection

(21:45) | Lessons on Reasoning and Bias

(26:55) | Final Takeaways and Action Steps


Tags: Clinical Reasoning, Internal Medicine, Diagnostic Accuracy, Hoofbeats, Cognitive Bias, Medical Education, Illness Scripts



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#182 Pleural Effusions: 5 Pearls Segment09 juil. 202500:36:15
  • Imaging Pearls | (01:12)
  • Deciding on Thoracentesis | (04:00)
  • Light’s Criteria and Pseudoexudates | (07:00)
  • Pleural Fluid Studies: pH and Cell Differential | (16:56)
  • Diagnosing and Treating Parapneumonic Effusions | (23:32)
  • Malignant Pleural Effusions: Diagnosis and Management | (30:39)


šŸ”¹ Sponsor: Oakstone CME’s ACP MKSAP Audio Companion

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šŸ”¹ Transcript and Show Notes


Tags: Internal Medicine, Medical Education, Pulmonology, CoreIM, Clinical Reasoning, critical care, pulm



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#181 July Stories 3.002 juil. 202500:15:58

Listen for some good laughs and relatable stories!

In this episode, we share raw and real stories from July — from rapid responses to unexpected kindness — and reflect on the emotional weight of starting out in medicine.

šŸ”¹ Sponsor:Ā NEJM Fellowship Program, clickĀ here to learn more and/or apply! Due Aug 1, 2025

šŸ”¹ Transcript and Show Notes

Prior July Stories:

July Stories 2.0 (2023)

July Stories (2019)

Timestamps:

(00:32) | Dr. Ali Trainor's First Day as an Intern

(03:00) | The Patient's Critical Condition and Emotional ResponseĀ 

(07:12) | Dr. George Tran's First Night ShiftĀ 

(10:38) | Dr. Ali Trainor's Second Rotation ExperienceĀ 

(14:01) | The Importance of Co-Intern


Tags:Ā CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Narrative Medicine, Humanities



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#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group25 juin 202500:26:41

How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and explore the REDUCE-AMI trial, which questions whether beta blockers are still needed for all.

Listen to this latest episode of Beyond Journal Club, a collaboration between Core IM and NEJM Group, where we put research into context tracing the arc of evidence, dissecting the clinical question, and exploring what the findings could mean for real-world patient care


šŸ”¹Ā Sponsor:Ā NEJM Fellowship Program, clickĀ here to learn more and/or apply!

šŸ”¹Ā Transcript and Show Notes


Timestamps:

(00:48) |Ā Background on Beta Blockers and Their Mechanism

(02:41) |Ā Historical Context of Beta Blockers in Heart Disease

(04:56) |Ā Capricorn Trial and Its Impact

(07:17) |Ā Emergence of Doubts About Beta Blockers

(10:09) |Ā Introduction to the REDUCED-AMI Trial

(15:52) |Ā Discussion on Trial Interpretation and Clinical Implications

(16:18) |Ā Comparison with Other Trials and Future Directions


Tags:Ā Ā CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Cardiology



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#179 Invasive Fungal Disease: 5 Pearls Segment11 juin 202500:45:02

šŸ”¹ What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46)

šŸ”¹ What are the main classes of fungi? (~11:35)

šŸ”¹ What are the pros and cons of B-D Glucan and Galactomannan (~19:16)

šŸ”¹ How to increase the yield of blood cultures? How to interpret yeast growth in sputum/BAL and urine cultures? (~ 30:42)

šŸ”¹ How is invasive fungal disease treated? (~ 35:14)

šŸ“ŒĀ Ā Sponsor:Ā Oakstone CME’s ACP MKSAP Audio Companion

Use the code "CORE30" for 30% off effective 11/1/25 through 1/31/26: https://www.coreimpodcast.com/MKSAP


šŸ“Œ Transcript & show notes

Tags: CoreIM, IMCore, Infectious Disease, Hospital Medicine, Hospitalist, ICU, Medical Education, Physician Assistant, Nurse Practitioner, Medical Student, mold



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#178 Continuous Glucose Monitor (CGM): 5 Pearls Segment02 juin 202500:33:34

šŸ”¹What are clinically relevant limitations of an A1c vs. a CGM (1:40)

šŸ”¹What do the different parts of the ambulatory glucose profile tell you? (09:59)

šŸ”¹What are common pitfalls, medications, lifestyle patterns that are important to ask your patient about when seeing them for a visit to manage blood sugar? (15:19)

šŸ”¹ How can you titrate insulin based on when you see the hypoglycemia on the ambulatory glucose profile (20:00)

šŸ”¹ When there is too much hyperglycemia, how do you titrate insulin when adding on GLP-1 agonists? (26:30)


šŸ“Œ Sponsor:Ā Ā NEJM Fellowship Program, clickĀ here to learn more and/or apply!

šŸ“Œ Transcript & show notes

Tags: CoreIM, IMCore, Endocrinology, Primary Care, Medical Education, Physician Assistant, Nurse Practitioner, Medical Student, diabetes management, insulin titration



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#177 Interventional Radiology (IR) 101: 5 Pearls Segment14 mai 202500:43:53

šŸ”¹When is an U/S vs. CT vs. MRI helpful before consulting Interventional Radiology?

šŸ”¹What factors go into an IR pre-op evaluation?

šŸ”¹ When do drains go in, and when do they come out?

šŸ”¹ When a patient has trouble with a drain, what are things you can do before calling IR?

šŸ”¹ What does outpatient IR follow up entail, and what does a capping trial of PCN tubes entail?


šŸ“ŒĀ Ā Sponsor:Ā Oakstone CME’s ACP MKSAP Audio Companion

Use the code "CORE30" for 30% off effective 11/1/25 through 1/31/26:Ā  https://www.coreimpodcast.com/MKSAP


Transcript & show notes

Tags: CoreIM, IMCore, Gastroenterology, Primary Care, Medical Education, Physician Assistant, Nurse Practitioner, Medical Student, Medical Imaging, Bleeding Assessment, Drain Management, Procedural Sedation



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#176 Constipation Medications: 5 Pearls Segment30 avr. 202500:39:43

šŸ”¹ High-yield reversible causes of constipation?Ā (02:26)

šŸ”¹ Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03)

šŸ”¹ Osmotic vs Stimulant Laxatives (15:06)

šŸ”¹ Suppositories and enemas? (25:39)

šŸ”¹Best practices with opioid induced constipation (34:05)


šŸ“ŒĀ Ā Sponsor:Ā FreedĀ is an AI scribe that listens and writes your note in < 30 seconds. FreedĀ learns your styleĀ over time and is HIPAA compliant!Ā 

Use the codeĀ CORE50Ā to get 50% off your first month withĀ Freed

šŸ“ŒĀ Earn CME credit with ACP for this episode!Ā CME-MOC creditĀ 

šŸ“ŒĀ Transcript and Show Notes


Tags: CoreIM, IMCore, Gastroenterology, GI Pharmacology, Digestive Health, Primary Care, Medical Education, Physician Assistant, Nurse Practitioner, Medical Student, Laxatives, Stool Softeners, Senna, Bisacodyl, Polyethylene Glycol, Bowel Regimen, Magnesium Citrate, Lactulose



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#175 A Revolution in HIV Prevention & The PURPOSE Trials: Beyond Journal Club Segment with NEJM Group16 avr. 202500:27:44

How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables, and then to the PURPOSE trials, which look at the use of long-acting lenacapavir as PrEP — a potential game-changer in the field of HIV.

Listen to this latest episode of Beyond Journal Club, a collaboration between CoreIM and NEJM Group, where we put research into context, telling the story of how we arrived at the current standard of care, appreciating the clinical question of the trial at hand, and interpreting what the findings may mean for these patients.


šŸ”¹Ā Sponsor:Ā Ā NEJM Fellowship Program, click here to learn more and/or apply!


šŸ”¹Ā Transcript and Show Notes


Timestamps:

(02:25) |Ā HIV PrEP Daily Truvada and Descovy

(07:48) |Ā On-Demand Prep

(13:25) |Ā Purpose Trials

(20:56) |Ā Discussion of Effectiveness to Efficacy


Tags:Ā Ā CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, HIV Prevention, Infectious Disease



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#174 Lp(a) and ASCVD Risk: 5 Pearls Segment02 avr. 202500:43:20

What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to interpret results, counsel patients, and navigate topics with limited data like aspirin and PCSK9 inhibitors in treatment.

šŸ”¹ Sponsor:Ā FreedĀ is an AI scribe that listens and writes your note in < 30 seconds. FreedĀ learns your styleĀ over time and is HIPAA compliant!Ā 

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šŸ”¹ Transcript and Show Notes

Timestamps:

(02:17) | Pearl 1: What makes Lp(a) unique? How does it raise ASCVD risk?

(10:32) | Pearl 2: Who should be tested for Lp(a)? When and why?

(16:54) | Pearl 3: Understanding and interpreting Lp(a) levels

(24:04) | Pearl 4: How does an elevated Lp(a) affect management?

(37:05)| Pearl 5: The role of aspirin and PCSK9 inhibitors in Lp(a)


Tags: CoreIM, Internal Medicine, Primary Care, Preventive Cardiology, Atherosclerosis, Lipid Management, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student



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#173 Hypercoagulability Workup: 5 Pearls Segment19 mars 202500:44:49

A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and practical approaches!

ļ»æšŸ”¹ Sponsor:Ā FreedĀ is an AI scribe that listens and writes your note in < 30 seconds. FreedĀ learns your styleĀ over time and is HIPAA compliant!Ā 

Use the codeĀ CORE50Ā to get 50% off your first month withĀ Freed

šŸ”¹Ā This episode is also sponsored by Factor!Ā Get fresh, ready-made meals delivered to your door. Use the codeĀ factorpodcastĀ for a special discount atĀ factor75.com.

Transcript and Show Notes

Timestamps:

(02:07) | Pearl 1: Reframing Provoked vs. Unprovoked to Reversibility

(09:12) | Pearl 2: How can Virchow's Triad help us categorize the etiology of a clot?

(17:01) | Pearl 3: What factors affect anti-thrombin III, Protein C and Protein S deficiency

(28:50) | Pearl 4: Is the Factor V Leiden or Prothrombin Gene Mutation as important as the family history?

(38:41) | Pearl 5: Spaced Repetition of Learning Points

Tags:Ā CoreIM, Internal Medicine, ClinicalPearls, Medical Education, IMCore, hospitalist, physician assistant, nurse practitioner, medical student, internal medicine, hematology



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#172 Microplastics and Macro CV Health Problems: Beyond Journal Club on APACHe Study with NEJM Group05 mars 202500:33:36

What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes?

Join us as we tackle these questions and discuss the APAChE study on microplastics and cardiovascular disease onĀ this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.

šŸ”¹ Transcript and Show Notes

šŸ”¹ Behind The Scenes YouTube Video

This episode is also sponsored by Factor!Ā Get fresh, ready-made meals delivered to your door. Use the codeĀ factorpodcastĀ for a special discount atĀ factor75.com.


Timestamps:

(02:24) | Introduction to Plastic's Key Players

(07:59) | Bradhill/Observational Work

(10:33) | APAChE Study Deep Dive

(18:03) | Discussion


šŸ“¢ Special Thanks:

šŸŽ™ļø Audio Editing: Jerome Reyes

šŸ“Š Graphics: Dr. Jimin Hwang


Tags:

CoreIM, Environmental Health, Medical Education, IMCore, Public Health, Clinical Pearls, Physician, Medical Student, Nurse Practitioner, Epidemiology



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