Cal replays one of the most amazing conversations he's ever had -- with a man who was in the bathroom on the 81 st Floor of the World Trade Center before starting work on the morning of 9/11/2001 when the hijacked plane hit. Michael Wright, a 30-year-old account executive at the time, got down to the ground only to look up and see the other tower falling on his head. Cal listens to the story every year to never forget the day and to focus on the power of resilience. But also for another reason this year – to remember how connected the United States was right after 9/11. The most connected Cal had ever seen it. Please send this conversation to one person you think might appreciate it.

Cal continues a summer of storytelling by passing on one about a player you might like to root for in this year's U.S. Open. The backstory of Taylor Townsend shows us how there are winds in life that hold us back and winds that push us forward. And the value of perseverance in between.

Cal talks with the futurist who tells us that artificial intelligence is going to be embedded in everything we do -- and that means many aspects of the world around us will be moving at an accelerated pace. His book, Superconvergence, looks at how AI will transform our lives as it is embedded in genetics and biotech. It could mean living longer, feeding billions and supercharging the economy. We don't want to think about the downside – which is why we must. Jamie's got a Ph.D. from Oxford, a Juris Doctor degree from Harvard Law School and he was the opening speaker at the 2023 Dubai future forum. He's also an ironman triathlete in his spare time. When Cal left the conversation, he felt like his IQ had spiked. You may feel the same.

Cal talks with the man who evolved from drinking a six-pack of Coca Cola every day as a boy to the author of Superlife: the 5 Simple Fixes that will make you healthy, fit and eternally awesome. Darin is also the co-host of the television show Down to Earth with Zac Efron, where the two go adventuring around the world to find healthy and sustainable ways to live. You may eat a little differently after listening to this conversation.

Listen to some amazing surgery stories this week about what it's like to operate on a child's brain from Dr. Jay Wellons, a pediatric neurosurgeon at the Monroe Carell Jr. Children's Hospital at Vanderbilt and the Vanderbilt University Medical Center. Jay is a gifted writer as well, as anybody who's read All That Moves Us can attest. Once the harrowing stories are told, Cal asks the neurosurgeon how he stays healthy amid the persistent tension. It's a question that probably applies to everybody who's worked in healthcare during COVID, and it calls for everybody's attention.

Morphogenesis has an immunotherapy treatment that has worked in five out of five clinical trials on skin cancer and it's nasty cousin, Merkel Cell cancer. The company's CEO, Dr. James Bianco, says that the treatment may work against any cancer. But he doesn't want anyone calling it The Cancer Vaccine. Cal gets some insight into the potential breakthrough, and the leaps we're making in the fight against cancer. If you know someone who's been touched by cancer, check this episode out. That means everybody.

​​Rich Palarea's introduction on Twitter reads: "I won't sleep until I fix $ waste in healthcare." Cal listens to the story of how Rich became CEO of Kermit, a company that uses technological transparency to reduce costs on surgical implants for hospitals. The conversation reveals how little we know about what goes on behind the scenes in some operating rooms. It also gives us hope that applying transparency across all aspects of healthcare will make life better for everyone. 

Cal takes a moment to pause and reflect on moments he had with two icons who said farewell recently in very different ways. Tennis great Serena Williams ended one of the most impactful careers in the history of any sport at the U.S. Open and the man who lifted The Iron Curtain, Mikhail Gorbachev, took his final breath at the age of 91. Cal tells two stories that showcase the origin of their influence. They both revolve around hugs. We should all take note.

Cal takes a moment to honor those impacted by the attack on the World Trade Center that killed more than 3,000 people in 2001. He replays his conversation with Michael Wright, who was working on the 81st floor on the morning the planes struck. When Michael made it down to the street, one of the twin towers collapsed on his head. Cal replays Michael's vivid description in this episode for two reasons. So that we'll never forget the day, as well as to alert us to the terrorist threat of this era: Fentanyl. This synthetic opioid is 50 times more powerful than heroin and much more inexpensive to produce. It's responsible for the death of more than 200,000 people in the USA over the last two years. 9/11 is a poignant alert that something needs to be done about Fentanyl. Now.

Many people have avoided going to the doctor during the time of Covid . . . unless they had Covid. This may have resulted in missing an early detection of cancer. So this podcast is a reminder to all those who've delayed checkups to make an appointment. Cal gets an exam, and now has peace of mind. He also puts the podcast to a checkup. Marketing guru Jason Harris, the CEO of the creative agency Mekanism, enters the conversation to show Cal that it's time for Big Questions to grow to wear many hats. Cal responds by setting in motion a non-profit to attack problems in healthcare. The Best Is Yet To Come. Thanks for coming on the journey.

Cal has spent his life writing stories and telling them on stage. Big Questions started after he told stories for three straight hours on Tim Ferriss's podcast. But Cal finds a new power in storytelling through Harvard's Annie Brewster, a physician who used her own story to help heal herself after being diagnosed with multiple sclerosis roughly twenty years ago. Annie went on to start a non-profit to help others understand their health problems through storytelling, and this conversation gives Cal the seed of an idea . . . and may help you, too.

Until this week, Cal never knew that more than ten percent of the people who signed the Declaration of Independence in 1776 were physicians. Doctors are now found in tech roles that can bring exponential improvements to the masses. Amazon's Adam Glasofer is a great example.

Johnny Crowder is motivation to all when it comes to changing the way you think about your health. He's actually rewired his brain to get the best possible behavior from himself. His life is an extreme example of overcoming mental health problems. But the work he's put in to understand the human brain can be used by anybody who needs to overcome ANY problem.

In his quest to go deep into artificial intelligence, Cal comes across a most unusual guest. Theresa Fesinstine speaks to AI in a most uncommon way – as if it were human. Almost as if she were a really good high school English teacher talking to her students in the most caring way. There's research that says this kind of approach gets the best out of AI. Listen up, and try it out.

For a couple of years now, Cal has been asking questions to get to the root of why we're all so disappointed with aspects of healthcare. This week, he speaks with a man whose created a game-changing solution which puts people back in control of their care with high-quality experiences at lower prices. It's called Transcarent. Listen up . . .  

Cal is introduced to a man who's orchestrated 4,000 college scholarships to students from low-income areas and who plans to extend 30,000 scholarships through an organization called Hope Chicago. This gets Cal to thinking about helping one child to become a doctor at a time when one in five healthcare workers has left the field during Covid. Pete makes that scholarship happen for Cal and Big Questions, and leaves Cal wondering how to generate 49 more!

Cal finds himself looking down different highways and byways in the wide arc of healthcare and begins to wonder about the ways to make the biggest impact. Then he awakens one night at 3 a.m. with an urge to relisten to the first podcast he did on the subject. It was with Navy surgeon and dermatologist Reagan Anderson before COVID. It resonates now more than ever.

Cal looks for a way to bring people together during the acrimony following the Supreme

Court decision reversing Roe vs. Wade and setting the stage for the prohibition of 

abortion in certain states. So he made an unusual decision to publish an episode that he was planning for September – during Prostate Cancer Awareness month. The idea behind it is for people of different sexes and opinions to share knowledge in a kind way – in this case about an often-misunderstood male organ. Dr. Neil Baum, a urologist from New Orleans, gives the primer. The hope is that we all become more curious and understanding of each other's health needs and opinions.  Because if we can't come together as a nation over healthcare, what can we come together over?

On average, every American eats 100 bowls of cereal a year. Most are filled with highly-sugared, highly-processed carbohydrates fronted by wonderful animations of characters that lure kids in to thinking they're breakfast pals. Cal used to be one of those kids, and he loved those sweet, crunchy cereals. Now, Cal wonders how much healthier America would be if it were eating cereals that taste great but contain virtually no sugar made by Magic Spoon. His conversation with company founder Gabi Lewis takes us all to new places. A healthy Birthday Cake cereal???

Cal meets two guys who've created an App that does not let you forget anything -- and creates a memory archive. That made Cal feel sharper and healthier in an instant. Not only is the Twos App free. But the founders gave Cal a two-dollar bill as a promotional gesture just to try it out. Cal did, and has been using the Twos App ever since. Founders Parker Klein and Joe Steilberg got so excited to come on Big Questions, they offered to Venmo $2 to anybody who tries the Twos App. Cal's sure this will delight listeners . . . but he hopes it doesn't bankrupt Parker and Joe.

The son of self-help guru Tony Robbins has become a coach with clients in 133 countries around the world. You'll see why when you listen to this conversation. You will definitely be in a better place to navigate your path after listening to this podcast!

Cal comes across an interesting situation when an 18-year-old college freshman develops back pain after donating blood. A campus doctor fears it could be a deadly pulmonary embolism and directs Ashton Marshall to the local Emergency Room. This could lead to many tests and high bills. Ashton's father, the author of Never Pay The First Bill, offers his son a strategy to keep the charges reasonable. Listen to Marshall Allen, and you'll have that same strategy.

Cal reads a story on ESPN.com that makes him cackle, and he reaches out to the writer to thank him for bringing laughter into his day. The conversation that ensues brings forth an amazing story about the loss of Ryan's toes and the surreal journey it takes him on. Pass this podcast on to anyone feeling down or miserable. They'll likely have a very different mindset after they're done: Gratitude.

Cal sees a newsmagazine with a headline that reads: THE BAD GUYS, ON YOUR PHONE, IN YOUR COMPUTER, FILLING YOUR EMAIL, MINING YOUR INFO, TRICKING YOUR LOVED ONES, IMPERSONATING YOU AND PLOTTING THEIR NEXT STEAL. He notices that The Tindler Swinder is one of Netflix's top-rated documentaries. And he observes how getting scammed affects the daily life and mental health of a friend. He gets an inside look from the victim of a massive scam and identify theft – the former wife of NBA all-star Jason Kidd. Joumana's story will keep you on guard.

Simply listening to the story of how Elliott and three buddies who were just out of college andfeeling lost during The Great Recession went on to create a company called Summit that connected thousands of innovators in the Tech space at conferences that filled hotels and cruises and led to their purchase of a majestic mountain in Utah, and along the way curated the wisdom of Jeff Bezos, Ted Turner, President Bill Clinton, the actress and founder of the billion dollar Honest company, Jessica Alba, and musician Quincy Jones, will give you the feeling that YOU can do anything! Listen up, check out the book Make No Small Plans and see what mountains you might be capable of moving! Cal wonders if a similar community could be created for the future of healthcare . . .

Chessboxing? What? Do the competitors pound each other in the head as they move pieces on the chessboard? It's actually a sport that is going to be on display at the Olympics in Paris this summer. It's not an official Olympic event. Yet. But three hundred thousand people stream events and it's only getting bigger and bigger. What does it mean for you? Listen to Matt Thomas's story.

After a dizzying few weeks of watching images of Vladimir Putin's invasion of the Ukraine and pondering the possibilities of a nuclear war, Cal senses it's time to step back and get perspective. He reaches out to Juliet Funt, author of the book A Minute To Think, for advice on getting the most out of himself during this crazy time. "Funt's wisdom around making space is priceless," says marketing guru Seth Godin. Cal embraces Funt's business tools to get the most out of his days. They will create great outcomes for you, as well. Guaranteed.

While speaking at a retreat for a group of investors, Cal asks about a basic educational guide to the stock market and saving money to make sure that any health care needs at the end of life can easily be met. He's turned on to The Personal Finance Club course and Jeremy Schneider. Which leads to this conversation. Anyone looking for a clear and time-tested way to save a nest egg will be happy they tuned into this week's podcast.

Cal looks back on experiences he's had with Muhammad Ali, Kobe Bryant and Larry King as a way of seeing forward into his journey to reshape healthcare. A story about Martin Luther King Jr.'s I Have A Dream Speech is also included in this episode. Each remembrance shows us how a tiny action – an introduction, a suggestion or a boost during a scary moment can be so impactful, and each reminds us how to get the most out of our lives.

Cal talks with the author of The Super Age, Decoding Our Demographic Destiny, about what our future looks like as America becomes an older nation as opposed to a younger one for the first time in its history. Bradley uses data from the past to predict what's coming and the results of this conversation are shocking to Cal. According to Bradley, the best is yet to come. Get ready to be optimistic.

Nido came to study in the United States from the Middle East when he was 17 years old with $50 in his pocket and built an extraordinary life through High Point University in North Carolina – where he is now president. During the last 17 years, Nido has grown the university from 90 acres to 500, from 18 buildings to 128 and from 1,400 students to 6,000. He talks about the power a strong home has over our attitude and behavior, and gives Cal and listeners tools to build and grow any enterprise. This episode is a feast of wisdom. 

Cal realizes that for the first time he is not feeling behind in technology because he has thrown himself into understanding AI. Conversations with experts on this podcast have made him feel more comfortable with what's coming – even if we don't know exactly what that is. This is the conversation that opened the door for him. It's with Linus Eckenstam – a designer in Barcelona who makes web forms a little more human. Cal hopes this episode will make everyone more comfortable feel a little more authentic in the age of AI.

The CEO of one of America's most innovative creative companies, Mekanism, shows Cal how to build a campaign through understanding an audience. This is new territory for Cal, who's spent a lifetime asking questions of people who've built great things – without ever having built anything himself. As Cal sets off on his journey to try to reshape healthcare, he knows he will have to build a platform. Jason sets the groundwork, and shows everybody how to shape their own messaging by using the right questions.

Cal checks in with the author of The Third Door, and comes away with two tools that can help anybody who feels stuck in life get to a better place. (And in times of COVID, there are plenty of people who feel stuck.) The tools are called The Sun and The Clouds and The Thirty-Day Challenge, and they don't require much time. Even if you don't think you need them, they just may surprise you and take you to an intriguing place. Or you could pass them on to somebody who is unmistakably stuck and definitely needs them. Either way, these tools will lead to a clearer New Year.

Mental health gets closer to home for Cal when a young acquaintance is brought to tears with harmful thoughts in front of Cal's house. This, after suicide and attempts shook a nearby college campus. It's clear that a huge number of people are dealing with mental health issues that are not being treated or acknowledged. Cal talks with Kevin Hines, who has devoted his life to suicide prevention after attempting to take his own life by jumping off the Golden Gate Bridge, about what we all can do to help. Awareness is key. The information Kevin passes on could save somebody's life.