In this episode, Dr. Micah Yu and Dr. Melissa Mondala discuss one of the most overlooked aspects of autoimmune disease: mental health. With depression and anxiety affecting more than half of all autoimmune patients, the conversation explores the deep connection between the nervous system, trauma, inflammation, and long-term healing.

Key Points:

• One in two people with autoimmune disease also has depression or anxiety.
• Mental health symptoms often appear years before autoimmune diagnosis.
• Emotional trauma, chronic stress, and neuroinflammation can all trigger or worsen autoimmune flares.
• The field of psycho-neuro-immunology explains how the brain, nervous system, and immune system interact.
• Childhood trauma (ACEs) significantly increases the risk of autoimmune conditions later in life.
• Early signs of depression and anxiety include sleep changes, appetite issues, mood swings, perfectionism, joint pain, rashes, and fatigue.

Root Causes of Mental Health + Autoimmune Disease:

• Chronic stress and trauma
• Hormonal fluctuations (e.g., PMS, menopause)
• Neurotransmitter imbalances
• Gut and microbiome dysfunction
• Environmental toxins and heavy metals
• Nutrient deficiencies (zinc, B vitamins, etc.)

Treatment Strategies:

• Nutrition: Whole foods rich in omega-3s, zinc, tryptophan, tyrosine, antioxidants
• Lifestyle: Daily movement, quality sleep, community connection
• Practices: Meditation, prayer, breathwork, vagus nerve activation (humming, singing)
• Supplements (under guidance): SAM-e, L-theanine, ashwagandha, tryptophan
• Psychotherapy, psychosomatic healing, and nervous system retraining

Featured Case Study:

A 60-year-old woman with long-standing rheumatoid arthritis saw dramatic improvement in pain, energy, and inflammation after focusing on nervous system regulation, sleep, and mental wellness. Her care plan included vagus nerve stimulation and lifestyle changes. Within 3 months, she was pain-free, off prednisone, and considering a return to nursing. Her recovery also positively impacted her son, who struggled with mental health issues.

Final Message:

Healing is possible — even after years of trying. When diet and medications aren’t enough, it’s time to address mental health, trauma, and the nervous system. This episode reminds us that what feels emotional is often physical, and that support, persistence, and the right tools can make all the difference.

Learn more or schedule a consult:

• Dr. Yu and Dr. Mondala’s clinic: https://myautoimmunemd.com
• Dr. Yu on YouTube: My Autoimmune MD
• Dr. Mondala on YouTube & Instagram: Dr. Melissa’s Kitchen

In this episode, Dr. Micah Yu and Dr. Melissa Mondala explore the rising epidemic of autoimmune disease. They unpack the root causes, early warning signs, and the whole-body approach needed for healing. They share personal clinical experiences, including a powerful success story using an anti-inflammatory protocol, and preview upcoming discussions on mental health, trauma, and psycho-neuro-immunology. The tone is both educational and hopeful, aimed at empowering patients and practitioners alike.

• 10% of the global population has autoimmune disease — and that number is rising.
• Autoimmunity affects multiple systems: rheumatology, neurology, endocrinology, GI, and beyond.
• These diseases are often missed or misdiagnosed, with patients cycling through many specialists.
• Women make up 80% of autoimmune cases.
• Autoimmune diseases include lupus, Hashimoto’s, RA, Crohn’s, type 1 diabetes, celiac, and more.
• Patients often develop multiple autoimmune conditions over time.
• Traditional medicine focuses on symptom suppression, not root cause resolution.

• Diet and lifestyle (nutrition, exercise, sleep)
• Environmental toxins (plastics, BPAs, PFAS, mold, heavy metals)
• Infections (Lyme, COVID, flu, mycoplasma, etc.)
• Medications and vaccines (as documented potential triggers)
• Genetics and epigenetics
• Chronic stress and trauma
• Psycho-neuro-immunology — the link between brain, immune system, and inflammation

• Fatigue and brain fog
• Rashes and joint pain
• GI issues (like bloody stools)
• Oral/nasal ulcers, dry eyes/mouth
• Hair loss

These signs are often subtle and systemic, making diagnosis difficult.

• Emphasis on a functional and integrative medicine approach
• Focus on Anti-inflammatory nutrition, Lifestyle changes (movement, sleep, stress), Avoiding or reducing toxin exposure, and identifying and managing infectious triggers
• Healing is possible with small, consistent changes — often starting with food and mindset

1. Lupus Diagnosis: A patient went 5 years misdiagnosed by 10+ doctors. Dr. Yu correctly diagnosed lupus using labs and clinical intuition.
2. RA Reversal with Diet: A long-term RA patient experienced a dramatic reduction in pain (from 9/10 to 1/10) in just one month using Dr. Yu’s anti-inflammatory protocol — no added meds or steroids.

• 50%+ of autoimmune patients struggle with depression and anxiety.
• Melissa introduces the concept of psycho-neuro-immunology: inflammation in the brain due to stress or trauma affects emotional regulation.
• Mental health support is crucial and will be discussed more deeply in the next episode.

• Dr. Micah Yu’s YouTube: My Autoimmune MD
• Dr. Melissa’s channel: Dr. Melissa’s Kitchen (healthy recipes)
• Clinic website: https://myautoimmunemd.com — based in Newport Beach, CA, offering telemedicine across the U.S.

“Our Story: Healing Autoimmunity, Medicine, and Each Other”

Here are the highlights from our very first episode!

• The origin story behind the podcast and why it’s deeply personal
• Dr. Micah Yu shares his journey with autoimmune arthritis, undiagnosed pain, and years of suffering through medical school and residency
• How nutrition, sleep, and lifestyle were missing pieces in traditional medical training
• The power of plant-based eating in reversing inflammation and chronic symptoms
• Dr. Melissa Mondala’s experience navigating the system as a doctor, caregiver, and seeker of integrative solutions
• Why their clinical training and personal pain fueled a passion for integrative, lifestyle, and functional medicine
• Reflections on medical culture, patient isolation, and the emotional weight of chronic illness
• What they wish every patient and doctor knew about healing from the inside out

Micah Yu, MD, MHA, MS, ABOIM, DipABLM, IFMCP

Dr. Micah Yu is a triple board-certified integrative rheumatologist who blends conventional medicine with holistic, nutrition-based healing to treat autoimmune and chronic inflammatory conditions. A patient himself, Dr. Yu brings a deeply personal perspective to his work, having reversed his own autoimmune arthritis through lifestyle and integrative medicine. He is certified in internal medicine, rheumatology, integrative medicine, lifestyle medicine, and functional medicine. As the founder of MyAutoimmuneMD and co-founder of Dr. Lifestyle Clinic, Dr. Yu empowers patients to address the root causes of illness and reclaim their health from the inside out.

Melissa Mondala, MD, MHA, MS, DipABLM

Dr. Melissa Mondala is a dual board-certified physician in Family and Lifestyle Medicine, with advanced training in Integrative Psychiatry and Integrative Medicine. As President of Dr. Lifestyle Clinic in Newport Beach—recognized by UC Irvine as a Public Health Site of Excellence—she pioneers a holistic, patient-centered approach to chronic disease. Dr. Mondala is a nationally recognized Lifestyle Medicine Intensivist, core faculty at Loma Linda University’s Preventive Medicine Department, and a passionate advocate for plant-based nutrition, mental health, and women's wellness. A sought-after speaker and educator, she combines cutting-edge science with deep compassion to empower lasting healing, especially for those silently suffering from autoimmune, mental health, and long COVID conditions. She shares practical inspiration for healthy living and cooking at @drmelissaskitchen.

For more information, please visit https://myautoimmunemd.com.

Description: Board-certified rheumatologist Dr. Aly Cohen joins Dr. Micah Yu to connect environmental exposures with inflammation and autoimmunity, then turn that science into practical, low-stress habits. From plastics and bisphenols to water, air, food, and personal-care choices, Dr. Cohen shares a simple framework to cut risk without overwhelm, and how she integrates these steps into rheumatology care and patient outcomes.

What listeners will learn:

• Learn what “toxic load” means in plain language and why Dr. Cohen is seeing more young patients with autoimmune issues in her rheumatology practice.
• Discover smart ways to cut plastic exposure at home.
• Learn Dr. Cohen’s “4 As” roadmap to reduce exposures step by step so people make progress without burnout.
• Discover high-impact upgrades for water and why simple filtration can be a game changer across a lifetime.
• Learn how to choose and wash produce to lower pesticide residues
• Discover where endocrine-disrupting chemicals hide in cosmetics and personal care
• Learn practical changes for the kitchen, such as ways to remove microplastics
• Discover how Dr. Cohen pairs lifestyle and exposure reduction with standard rheumatology treatments to improve inflammation and quality of life.

Short bio for Dr. Aly Cohen:

Dr. Aly Cohen is a board-certified rheumatologist and integrative medicine physician with more than two decades of clinical experience. Her work focuses on how everyday environmental exposures influence hormones, immunity, and inflammation, and on translating that science into simple habits patients can sustain. In practice and public education, she teaches practical steps for safer water, food, air, and personal-care choices, and how to layer these into rheumatology care to support symptom control and long-term health.

Dr. Aly Cohen’s Website: https://thesmarthuman.com/ 

Link to Dr. Cohen’s Book: “Detoxify: The Everyday Toxins Harming Your Immune System and How to Defend Against Them” 

Host Bio:

Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration.

He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted therapies with nutrition, sleep, movement, and stress resilience.

Website: https://myautoimmunemd.com/

Summary

In this in-depth interview, Dr. Micah Yu speaks with Dr. Ty Vincent, founder of Low Dose Immunotherapy (LDI), about his groundbreaking work in retraining the immune system. Dr. Vincent shares his journey from conventional medicine to developing LDI, explains how it differs from traditional allergy therapies and homeopathy, and reveals the remarkable outcomes he’s seen in patients with autoimmune and chronic illnesses. Together, they explore real-world success stories, the science of molecular mimicry, and why focusing on mechanisms rather than diagnoses may be the future of medicine.

Key Takeaways

• Discover how Dr. Vincent’s path from family medicine to integrative care led him to create LDI.
• Learn the difference between Low Dose Allergen Immunotherapy (LDA) and Low Dose Immunotherapy (LDI).
• Explore how LDI addresses immune tolerance rather than suppression, and why it works for conditions beyond allergies.
• Hear case studies of patients with rheumatoid arthritis, Crohn’s disease, celiac disease, Lyme disease, Hashimoto’s, psoriasis, and more who experienced remission or dramatic improvements.
• Understand the concept of molecular mimicry and its role in autoimmunity.
• See how LDI provides a safer, low-risk alternative to lifelong immunosuppressive drugs.
• Gain insight into Dr. Vincent’s ongoing innovations, including potential breakthroughs for type 1 diabetes.

This conversation highlights a profound shift in how we can view and treat chronic illness. Instead of suppressing the immune system, Dr. Vincent’s work with LDI shows what’s possible when we restore tolerance and reprogram the body’s natural defenses. It’s an eye-opening discussion that offers hope for anyone struggling with autoimmunity or unexplained chronic conditions.

Host Bio:

Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration.

He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted therapies with nutrition, sleep, movement, and stress resilience.

Website: https://myautoimmunemd.com/

CIRS, Mold, and Autoimmunity: Getting Off the Inflammation Roller Coaster

This is an encouraging and educational interview for anyone navigating Chronic Inflammatory Response Syndrome (CIRS) Dr. Melissa Mondala sits down with Jenny Johnson, a CIRS guide and community-builder, to unpack how biotoxin exposure from water-damaged buildings, mold, bacteria, and Lyme can drive chronic inflammation that mimics or even triggers autoimmune disease. They cover what to look for, how to differentiate CIRS from conditions like lupus, MS, and RA, and why environmental cleanup, sleep, nervous system support, and community are foundational. Jenny also shares moving recovery stories and practical ways families can pace healing without burning out.

CIRS is a chronic inflammatory response to biotoxins the body cannot easily clear. Symptoms can mirror lupus, MS, and RA, and CIRS may coexist with or trigger autoimmune flares. Taking a careful timeline, targeted labs, and sometimes imaging helps sort out what to treat first.

Key takeaways

• Learn what CIRS is and how it overlaps with autoimmunity.
• Discover why “remove the exposure” is step #1.
• Cleaning up or leaving a water-damaged environment reduces daily biotoxin load.
• Explore "pairing" detox strategies so the immune system can calm and autoimmune symptoms become more manageable.
• Learn the “brain on fire and brain on ice” model.
• Discover the early anchors of recovery.
• Learn why community speeds healing.
• Discover hope through real-world stories.

CIRS can cause anxiety, depression, panic, rage, and cognitive issues like brain fog and executive dysfunction. Having a coach or community to be your “borrowed brain” reduces overwhelm while you recover.

Prioritize sleep and simple nervous system supports. Add nutrition shifts toward anti-inflammatory eating, then layer movement as capacity returns. Passive vagus-nerve supports can help when you are too depleted to do more.

Jenny’s CIRS Healing Collective (https://cirshealingcollective.mn.co/landing) meets weekly to share practical tips, host guest experts, and reduce loneliness. Safe, validating connection supports the parasympathetic nervous system and helps people stay on the “healing track.”

Jenny shares recoveries in her family from Lyme and mold injury, and a child’s neurodivergent symptoms easing after addressing environmental causes. Parents are encouraged to keep pressing for answers.

Conclusion

CIRS is fixable, and addressing it can dramatically change the trajectory of autoimmune symptoms. Start with a solid history, test what matters, remove exposures, and anchor sleep and nervous system care. Do less, but do it on the right track. Most of all, do not do this alone. Community and a clear plan make the path lighter and faster.

Connect with Jenny Johnson

• Simplified Wellness Designs: https://simplifiedwellnessdesigns.com
• The CIRS Healing Collective https://cirshealingcollective.mn.co/landing

Jenny Johnson is a leading expert in Chronic Inflammatory Response Syndrome (CIRS) and complex environmental illness. She is a Shoemaker Certified Coach, and drawing on years of clinical research and personal experience, she helps patients navigate the often-overlooked world of mold toxicity, biotoxin exposure, and neuroimmune dysfunction. Jenny is known for her deeply compassionate, whole-person approach and her ability to distill complex protocols into practical, healing strategies that work in the real world.

Host Bio:

Dr. Melissa Mondala is a triple specialist in family medicine, lifestyle medicine, and integrative/primary care psychiatry. She is double board certified in family medicine and lifestyle medicine, completed her family medicine residency and Lifestyle Medicine Fellowship at Loma Linda University Health, and earned her MD from Chicago Medical School along with master’s degrees in Health Administration and Biomedical Science. Dr. Mondala is co-founder of Dr. Lifestyle in Newport Beach, where she provides direct primary care, integrative mental health, and lifestyle-based prevention for patients locally and via telehealth.

She has served as core faculty in Preventive/Lifestyle Medicine at Loma Linda University and has contributed to national education in lifestyle medicine. She also co-hosts the Autoimmune Alchemy podcast with Dr. Micah Yu and leads the Integrative Mental Health Summit, bringing root-cause strategies for anxiety, mood, and brain health to a wider audience. Her approach blends diagnostics and conventional care with nutrition, sleep, movement, stress tools, and community to help patients reduce inflammation and build long-term resilience.

Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration.

He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted therapies with nutrition, sleep, movement, and stress resilience.

Website: https://myautoimmunemd.com/

In this groundbreaking conversation, Dr. Micah Yu speaks with retired rheumatologist Dr. Alfred Miller, who spent 40 years in practice and training at the Mayo Clinic. Dr. Miller shares his personal journey of discovering how Borrelia infections (often mislabeled as Lyme disease) may underlie many neurological and autoimmune conditions.

From misdiagnosis in academic institutions to overlooked testing protocols, he reveals why conventional approaches often miss the mark — and how proper testing, treatment, and even unconventional therapies like bee venom and stem cells can change lives.

Key Takeaways

• Why Borrelia infection is a “great imitator,” often misdiagnosed as ALS, MS, dementia, and other chronic diseases
• The flaws in current Lyme disease testing — and why omitting bands 31 & 34 on the Western blot leads to false negatives
• How Borrelia’s 28-day reproductive cycle makes short-term antibiotic treatment ineffective
• The role of cyst-busting medications and pulsed antibiotic protocols in treatment
• Case studies: how Dr. Miller’s daughter-in-law lived seven years beyond a 4-month ALS prognosis after proper treatment
• Why Dr. Miller believes autoimmune disease is a mislabel, and many cases are driven by Borrelia
• Fascinating integrative therapies, including bee venom’s ability to eradicate Borrelia and stem cell use in repairing neurodegenerative damage
• The importance of specialized labs like IGeneX (U.S.) and ArminLabs (Europe) for accurate tick-borne disease testing

The link betweenBorrelia infections, which cause Lyme disease, and autoimmune disorders is a complex and evolving area of medical research. A Borrelia infection can trigger autoimmune responses in genetically predisposed individuals through several mechanisms, including molecular mimicry and the induction of chronic inflammation.

The resulting immune dysfunction can lead to the development of specific autoimmune conditions, or it can produce symptoms that closely mimic those of autoimmune diseases. 

If you’ve ever wondered about the root causes of autoimmune disease, dementia, ALS, or rheumatoid arthritis, this episode will open your eyes to a different paradigm of medicine.

Host Bio:

Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration.

He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted therapies with nutrition, sleep, movement, and stress resilience.

Website: https://myautoimmunemd.com/

When Infections Inflame the Mind: Lyme, MS, and the Gut–Brain Connection

Dr. Darin Ingels connects the dots between chronic infections (like Lyme), the gut–brain axis, and neuroinflammation—explaining “leaky gut/leaky brain,” vagus-nerve signaling, mast-cell activation, and why mood, brain fog, and sleep often shift with immune activity. He shares practical supports—from joy practices to potent, targeted herbs—and how to vet supplement quality for safety and results.

Key takeaways:

Leaky gut and “leaky brain” often travel together; restoring gut function improves brain function.

The vagus nerve can transmit gut signals that open the blood–brain barrier and drive neuro-inflammation.

In Lyme and MS, immune cross-reactivity and mast-cell activation can inflame brain and nerves, contributing to anxiety, depression, OCD, and brain fog.

Joy and regulation tools matter: music, humor, nature, and realistic activity resets help shift mental state on hard days.

Herbal medicine is multi-targeted: combinations can modulate inflammation, immunity, hormones, and circulation—often at low doses with strong effects.

Adaptogens to balance stress/cortisol: eleuthero (Siberian ginseng), rhodiola, holy basil, Ashwagandha—choose by symptom pattern (e.g., “tired-and-wired”).

Sleep supports: lemon balm, chamomile, passionflower, kava, California poppy; nutrients like magnesium and 5-HTP/L-tryptophan help with staying asleep.

Pain/inflammation options: highly bioavailable curcumin, Boswellia (frankincense), white willow bark, and devil’s claw (Harpagophytum).

Quality matters: look for GMP certification and third-party testing; request Certificates of Analysis; be cautious with heat-exposed or counterfeit online products.

Forms and safety: tinctures, capsules, teas, glycerites—many herbs are GRAS with low toxicity when sourced and dosed correctly.

Conclusion: Integrative mental health isn’t brain-only; it’s gut, immune, nerves, and daily rhythms working together. With clearer roots (infection, mast cells, barrier integrity) and practical tools (tailored herbs, joyful resets, vetted supplements), you can calm neuro-inflammation and support steadier mood, sleep, and cognition, step by step.

Host Bio:

Dr. Melissa Mondala is a triple specialist in family medicine, lifestyle medicine, and integrative/primary care psychiatry. She is double board certified in family medicine and lifestyle medicine, completed her family medicine residency and Lifestyle Medicine Fellowship at Loma Linda University Health, and earned her MD from Chicago Medical School along with master’s degrees in Health Administration and Biomedical Science. Dr. Mondala is co-founder of Dr. Lifestyle in Newport Beach, where she provides direct primary care, integrative mental health, and lifestyle-based prevention for patients locally and via telehealth.

She has served as core faculty in Preventive/Lifestyle Medicine at Loma Linda University and has contributed to national education in lifestyle medicine. She also co-hosts the Autoimmune Alchemy podcast with Dr. Micah Yu and leads the Integrative Mental Health Summit, bringing root-cause strategies for anxiety, mood, and brain health to a wider audience. Her approach blends diagnostics and conventional care with nutrition, sleep, movement, stress tools, and community to help patients reduce inflammation and build long-term resilience.

I sat down with Dr. John Neustadt, naturopathic doctor and #1 Amazon bestselling author, reveals why bone density tests only predict 44% of fractures and how MK-4 vitamin K2 reduces fractures 70%—better than Fosamax.

We discuss shocking statistics: 1 in 19 women on SSRIs break bones, acid blockers strip minerals causing hip fractures, and strontium causes blood clots. Dr. Neustadt explains the Mediterranean diet's 20% risk reduction, the 0.6g protein per pound formula, and how HRT builds bone better than bisphosphonates that fail to prevent primary hip fractures.

1. Bone density tests only predict 44% of women's fractures, 21% of men's
2. Fosamax doesn't prevent primary hip fractures—only vertebral
3. 1 in 19 women on SSRIs for 1-5 years will break a bone
4. MK-4 (45mg) reduces fractures 70%+ in clinical trials
5. Mediterranean diet: 20% less osteoporosis, 21% fewer hip fractures
6. Protein formula: 0.6g per pound body weight minimum
7. Strontium ranelate: 1 blood clot per fracture prevented
8. HRT (estrogen + testosterone) builds bone safely when appropriate
9. Men need estradiol tested—testosterone converts to it for bone building
10. Sleep <6 hours = 17% of fractures in elderly

02:00 90% Not Tested: The Underdiagnosis Crisis

03:00 SSRIs & Acid Blockers Destroy Bones

05:00 Focus on Fractures, Not Just Bone Density

07:00 Pediatric Condition with Geriatric Consequences

09:00 H. Pylori & Acid Reflux Root Causes

10:00 Fosamax Doesn't Prevent Hip Fractures

12:00 36% Die Within a Year from Hip Fracture

14:00 Dr. Neustadt's Mother-in-Law Broke Hip on Fosamax

16:00 Mediterranean Diet: 20% Osteoporosis Reduction

18:00 The Missing Protein: 0.6g Per Pound Formula

21:00 Debunking 150-200g Protein Myths

23:00 Sleep & Fracture Risk: Under 6 Hours Dangerous

27:00 Only 4 Nutrients Reduce Fractures Clinically

30:00 MK-4 vs MK-7: Why MK-4 Wins

33:00 45mg MK-4 Approved in Japan Since 1990s

36:00 Strontium: Blood Clots for Every Fracture Prevented

42:00 Hormone Replacement: Estrogen, Progesterone, Testosterone

46:00 Men Need Estradiol for Bone Building

49:00 Reversing T-Scores: Real Patient Outcomes

51:00 NBI Health & Strong Bones Guarantee

Dr. John Neustadt, ND

Naturopathic Doctor & Osteoporosis Expert

Credentials: Naturopathic Doctor (Bastyr University), Founder/President Nutritional Biochemistry Inc., 100+ published medical articles, #1 Amazon bestselling author

Book: "Fracture Proof Your Bones: A Comprehensive Guide to Osteoporosis"

Specialization: Integrative osteoporosis treatment, MK-4 vitamin K2 research, fracture prevention, hormone optimization

Website: nbihealth.com

Products: MK-4 + D3 (3 calcium doses: 1000mg, 400mg, none)

Guarantee: Strong Bones Guarantee - bone density stabilizes/improves in 6 months

Dr. Micah Yu, DC, CFMP

Functional Medicine Practitioner & Host of AutoImmune Alchemy

Dr. Micah Yu is a doctor of chiropractic and certified functional medicine practitioner specializing in autoimmune conditions and chronic illness. He recognizes mold exposure as a common root cause of autoimmune disease, particularly in patients with long-haul COVID who suddenly develop mold sensitivities. Dr. Yu is passionate about educating his community on environmental toxins and bringing expert voices like John Banta to help patients understand the hidden triggers affecting their health. He practices integrative medicine with his wife, creating a dynamic team dedicated to uncovering root causes and supporting patients on their healing journey.

Mission: Blending science with soul to transform autoimmune struggles into healing alchemy

AutoImmune Alchemy is a podcast dedicated to the autoimmune community, offering hope, validation, and evidence-based solutions for those struggling with complex chronic conditions.

Hosted by Dr. Micah Yu, the show explores root causes like mold exposure, infections, and environmental toxins that traditional medicine often overlooks. Each episode features expert interviews and cutting-edge treatments to help listeners understand the "why" behind their illness and find pathways to healing.

Connect with AutoImmune Alchemy:

1. Website: MyautoimmunemdHome – New
2. Instagram: @myautoimmunemd
3. Facebook: @MYAutoimmuneMD
4. YouTube: @myautoimmunemd
5. Email: contact@myautoimmunemd.com

Subscribe & Review: Available on Apple Podcasts, Spotify, and all major podcast platforms. If this episode helped you understand mold's role in chronic illness, please leave a 5-star review!

This episode is for educational purposes only and does not constitute medical advice. Always consult with your qualified healthcare provider before starting any new treatment or remediation. Individual results may vary.

In this episode, I sit down with James and Dahlia Marin, integrative dietitians specializing in SIBO and IBS, to explore how food relationships shape healing and why all autoimmunity begins in the gut.

Dahlia shares her Hashimoto's journey—bringing antibodies from over 3,500 (off the charts) to nearly normal using food as medicine. We discuss how gut inflammation progresses to autoimmune diseases, the vagus nerve "elevator" connecting gut and brain (fight→constipation, flight→diarrhea), and practical tools like gratitude before meals and anti-inflammatory "fire extinguisher" foods that shift your microbiome with every meal.

Key Takeaways

- All autoimmunity begins in gut - SIBO/IBS are early warnings

- Dahlia's antibodies: 3,500+ to near-normal with food

- Location matters - test before taking probiotics

- Anti-inflammatory foods: antioxidants, omega-3s, vitamin D, fiber

- Vagus nerve connects gut-brain (fight→constipation, flight→diarrhea)

- Calm nervous system before eating: gratitude, mantras, breathwork

- Microbiome shifts with EVERY meal

- Taste buds change to crave healthier foods over time

- Repair barrier with protein, amino acids, gooey foods

- Ask food relationship before giving elimination diets

Chapters & Timestamps

02:00 Autoimmune & Gut Health Connection

04:00 Bloating to Autoimmune: The Timeline

05:00 Anti-Inflammatory "Fire Extinguisher" Foods

07:00 Location Matters: Don't Take Probiotics Blindly

09:00 Dahlia's Hashimoto's: 3,500+ to Normal

12:00 Vagus Nerve: The Gut-Brain Elevator

13:00 Fight/Flight/Freeze/Fawn & GI Symptoms

15:00 Sustaining Healthy Lifestyle

16:00 Microbiome Shifts with Every Meal

17:00 Married to Health Resources

Guest Details

James & Dahlia Marin, RD - Integrative Dietitians, Married to Health Founders

Credentials: Registered Dietitians specializing in SIBO, IBS & autoimmune disease. Dahlia: Hashimoto's survivor (antibodies less than 3,500 to near-normal).

Specializations: SIBO/IBS therapy, autoimmune nutrition, gut-brain connection, nervous system regulation, food relationship healing.

Philosophy: "Heal with each meal, feel with each meal" - every meal shifts microbiome toward healing or harm.

Connect with James & Dahlia Marin

Website: www.marriedtohealth.com (hub for all resources)

Social Media: @marriedtohealth (all platforms)

Services & Programs:

Private practice with 8+ specialized dietitians

Good Gut SIBO/IBS self-paced program

One-on-one nutrition sessions

eBooks & educational resources

Regenerative Nutrition & Gut Health Experience (October, Southern California in-person event)

Melissa Mondala, MD, MHA, MS, DipABLM

Dr. Melissa Mondala is a dual board-certified physician in Family and Lifestyle Medicine, with advanced training in Integrative Psychiatry and Integrative Medicine. As President of Dr. Lifestyle Clinic in Newport Beach—recognized by UC Irvine as a Public Health Site of Excellence—she pioneers a holistic, patient-centered approach to chronic disease. Dr. Mondala is a nationally recognized Lifestyle Medicine Intensivist, core faculty at Loma Linda University’s Preventive Medicine Department, and a passionate advocate for plant-based nutrition, mental health, and women's wellness. A sought-after speaker and educator, she combines cutting-edge science with deep compassion to empower lasting healing, especially for those silently suffering from autoimmune, mental health, and long COVID conditions. She shares practical inspiration for healthy living and cooking at @drmelissaskitchen.

Mission: Blending science with soul to transform autoimmune struggles into healing alchemy

AutoImmune Alchemy is a podcast dedicated to the autoimmune community, offering hope, validation, and evidence-based solutions for those struggling with complex chronic conditions.

Hosted by Dr. Micah Yu, the show explores root causes like mold exposure, infections, and environmental toxins that traditional medicine often overlooks. Each episode features expert interviews and cutting-edge treatments to help listeners understand the "why" behind their illness and find pathways to healing.

Connect with AutoImmune Alchemy:

1. Website: MyautoimmunemdHome – New
2. Instagram: @myautoimmunemd
3. Facebook: @MYAutoimmuneMD
4. YouTube: @myautoimmunemd
5. Email: contact@myautoimmunemd.com

Subscribe & Review: Available on Apple Podcasts, Spotify, and all major podcast platforms. If this episode helped you understand mold's role in chronic illness, please leave a 5-star review!

This episode is for educational purposes only and does not constitute medical advice. Always consult with your qualified healthcare provider before starting any new treatment or remediation. Individual results may vary.

In this episode of Autoimmune Alchemy, Dr. Melissa Mondala welcomes Dr. Peter Kan — board-certified chiropractor, functional neurologist, and functional medicine expert known for bridging the gut–brain–immune connection. Dr. Kan works extensively with Hashimoto’s, rheumatoid arthritis, lupus, Sjögren’s, mixed connective tissue disease, MS, and patients with “autoimmune of unknown origin.” In this conversation, he breaks down why autoimmune patients so often struggle with food sensitivities, inflammatory flares, neurological symptoms, and overlapping autoimmune conditions thattraditional medicine misses. He explains the difference between allergies, sensitivities, and intolerances, why “food can be medicine or poison,” and how immune pathways like T-reg cells, Th17 activation, NF-kB, and leaky gut shape the autoimmune experience. He also shares strategic supplements, lifestyle foundations, and a practical roadmap for people who are overwhelmed, undiagnosed, or stuck in flare cycles.

TimeStamps

[0:00] — Understanding the Gut–Brain–Immune Connection

[1:40] — How Food Sensitivities Trigger Autoimmune Flares

[3:27] — Why Autoimmune Symptoms Spread Throughout the Body

[5:44] — Allergies vs. Sensitivities vs. Intolerances Explained

[8:34] — Foundational Supplements for Reducing Inflammation

[10:54] — T-Reg Cells, Glutathione & Immune Modulation

[14:17] — Elimination Diets, Testing & Reintroductions

[16:57] — Personalizing Your Autoimmune Nutrition Plan

Key Takeaways

• Discover how food sensitivities ignite autoimmune flares by ramping up the immune system and triggering tissue inflammation.
• Understand why many patients have “autoimmune of unknown origin” long before receiving an official diagnosis.
• Explore the difference between allergies (IgE), sensitivities (IgG/IgA), and intolerances (enzyme-based) — and why each requires a different treatment approach.
• Learn how food reactions can show up as fatigue, brain fog, sinus issues, weight changes, joint pain, skin symptoms, or mood shifts — not just digestive problems.
• Uncover how regulatory T-cells work as the “brake pedal” of the immune system, and why supporting them helps quiet autoimmune activity and move toward remission.

Dr. Peter Kan brings clarity to one of the most confusing and overwhelming parts of autoimmune disease: the relationship between food, inflammation, and immune dysregulation. His science-backed but practical approach helps patients understand why they react to so many foods, how to begin healing gut and immune pathways, and how to move toward remission through immune modulation — not fear or restriction. This conversation offers hope, direction, and a clear roadmap for anyone lost in the world of autoimmune flares.

Welcome to another episode of Autoimmune Alchemy, Dr. Micah Yu sits down with Dr. Kara Wada — board-certified allergist, immunologist, lifestyle medicine physician, Sjögren’s patient, and founder of The Immune Confidence Institute. Dr. Wada opens up about her long diagnostic journey with Sjögren’s, why so many patients are dismissed or misdiagnosed, and how clinical “gray zone” diseases like seronegative Sjögren’s, MCAS, dysautonomia, and chronic fatigue often fall through the cracks in modern medicine. She also shares the lifestyle changes, supplements, and clinical trial therapy (dazodalibep) that changed her health, plus the innovative lymph-node–targeted allergy treatment she now offers in her clinic.

Time Stamps

[0:00] — Welcome & Introduction

[1:07] — Early Symptoms & Missed Red Flags

[3:45] — Diagnosis Journey & Lab Findings

[6:12] — What Sjögren’s Really Is

[7:50] — Dryness Isn’t Always the First Symptom

[9:26] — Misrouted Specialists & Delayed Diagnosis

[9:50] — Full Symptom Breakdown

[14:16] — Lifestyle Changes That Helped

[15:30] — New Sjögren’s Drug Trial (Dazodalibep)

[18:10] — Future Treatments & Seronegative Gap

[19:39] — Supplements That Helped

[23:14] — “Clinical Ghosts” & Why Patients Are Dismissed

[27:17] — Rethinking Mast Cells & MCAS

[29:06] — ISLIT Protocol (Lymph-Node Immunotherapy)

[30:30] — Closing & Part 2 Teaser

Key Takeaways

Discover why Sjögren’s isn’t rare — only rarely diagnosed — and how normal labs can still hide the disease.

Understand why dryness doesn’t always appear first and how neurological issues, fatigue, migraines, and POTS often come earlier.

Learn how over-reliance on blood work leads doctors to dismiss patients whose symptoms don’t fit textbook patterns.

Uncover the deep neurological involvement in Sjögren’s, including dizziness, orthostatic intolerance, and chronic headaches.

Explore the lifestyle tools that helped Dr. Wada improve, including sleep optimization, stress management, and plant-forward nutrition.

Autoimmune patients can be overlooked — even when the symptoms are loud and life-altering. Dr. Kara's perspective as both a physician and a patient brings clarity, compassion, and validation to a community that’s often dismissed. From redefining what Sjögren’s really looks like to exploring groundbreaking new therapies, this conversation offers hope and direction for anyone navigating immune-driven illness. #podcast #autoimmune

In this episode of Autoimmune Alchemy, host Dr. Micah Yu speaks with Dr. Kelly McCann, an expert in internal medicine, functional medicine, and environmental medicine, about chronic illnesses and their root causes.

Dr. McCann discusses the concept of total toxic load and how various factors such as mold exposure, chronic infections like Lyme disease, and environmental toxins contribute to complex chronic conditions. She explains the various symptoms and diagnostic challenges of these illnesses, particularly emphasizing the importance of early identification and personalized treatment.

Dr. McCann also emphasizes the role of mind-body-spirit connection in the healing process and how trauma and emotional well-being can impact physical health. Additionally, the discussion covers hypermobility, Ehlers-Danlos syndrome (EDS), and Mast Cell Activation Syndrome (MCAS), providing insights into their management and treatment. This episode serves as a valuable resource for those seeking a deeper understanding of chronic illnesses and how to navigate their complexity.

Here are some time stamps to support you.

00:00 Introduction and Guest Welcome

01:25 Understanding Chronic Illnesses and Root Causes

02:08 The Concept of Total Load and Environmental Medicine

03:27 Mold and Mycotoxins: A Major Player

04:15 Chronic Infections and Their Impact

06:19 Environmental Toxins and Genetic Susceptibilities

07:36 Diagnosing and Treating Mold Toxicity

21:07 Mind-Body-Spirit Connection in Healing

23:27 Exploring Trauma and Emotional Healing

32:11 Energy Medicine and Self-Discovery

38:02 Lyme Disease and Co-Infections

39:48 A Family's Lyme Disease Journey

40:13 Understanding Lyme Disease Transmission

41:08 Divergent Views on Lyme Disease

44:08 Chronic Lyme and Functional Medicine

47:06 The Importance of Asking 'Why' in Medicine

54:03 Hypermobility and Ehlers-Danlos Syndrome

01:07:29 Mast Cell Activation Syndrome Explained

01:15:48 Concluding Thoughts and Resources

Uncover the truth behind chronic illnesses with Dr. Micah Yu and Dr. Kelly McCann.

From Lyme disease to Mast Cell Activation Syndrome, this episode explores the root causes and innovative treatments for complex conditions. Don't miss this insightful conversation on Autoimmune Alchemy! #IntegrativeMedicine #PodcastLife

Women often first meet autoimmunity during hormonal transitions like perimenopause and menopause. In this conversation, in this episode, Dr. Melissa Mondala and Dr. Jennifer Roelands (OB-GYN, integrative and functional medicine) unpack how shifting estrogen and progesterone interact with the immune system, why the gut–brain–hormone axis matters for mood and symptoms, and what to do first if you are seeing new labs, new aches, or a metabolism that no longer plays by your old rules. You will hear practical ways to lower inflammation, protect bone and muscle, choose labs that actually guide care, and build “low-hanging fruit” habits that stick.

Key takeaways

• Hormone transitions can “flip on” latent genes and unmask autoimmunity; gut health and hormone metabolism are tightly linked.
• Do not skip the gut: the estrobolome, serotonin production, barrier integrity, and antibodies formed in the gut influence thyroid and joint autoimmunity.
• Start small to beat overwhelm: stack easy “wins” such as step-ups, resistance bands, or brief “exercise snacks” while you build consistency.
• Protect bone and muscle: lift 2–3x weekly, add protein and fiber, and consider DEXA earlier than 65 to get a baseline.
• Labs that help: iron panel, vitamin D, CRP, fasting insulin, thyroid panel, and cycle-timed sex hormones; wearables or CGM can add useful data.
• Options exist: HRT is one path; omega-3s, fiber, magnesium (glycinate), curcumin, and targeted botanicals can also support symptoms and sleep.
• Perimenopause is more than hot flashes: watch for unusual signs like ear itching, body-odor changes, recurrent UTIs, libido shifts, or oral-health changes.

Suggested chapters

00:00 Intro and guest background

00:26 Why autoimmunity often appears in perimenopause

00:29 Gut–hormone metabolism, estrobolome, neurotransmitters

00:31 Stress load and “low-hanging fruit” habit building

00:34 Muscle and bone loss, strength training that fits pain levels

00:36 HRT, DEXA baselines, and fracture risk context

00:39 Supplement staples: omega-3s, fiber, magnesium, curcumin

00:42 Weight and metabolism changes, personalized nutrition

00:44 Unusual symptoms of perimenopause

00:46 Early or premature menopause and risk profile

00:49 Finding the right clinician; advocating for labs

00:51 What to test and how to time hormones

00:53 Where to find Dr. Roelands and her practice

Perimenopause is a whole-system transition. Pair smart medical care with gut support, resistance training, sleep, stress tools, and cycle-aware labs. Start with one easy win, get a baseline DEXA earlier, and build from there. The goal is not perfection. It is steady, sustainable progress that protects your brain, bones, and immune system.

Host Bio:

Dr. Melissa Mondala is a triple specialist in family medicine, lifestyle medicine, and integrative/primary care psychiatry. She is double board certified in family medicine and lifestyle medicine, completed her family medicine residency and Lifestyle Medicine Fellowship at Loma Linda University Health, and earned her MD from Chicago Medical School along with master’s degrees in Health Administration and Biomedical Science. Dr. Mondala is co-founder of Dr. Lifestyle in Newport Beach, where she provides direct primary care, integrative mental health, and lifestyle-based prevention for patients locally and via telehealth.

She has served as core faculty in Preventive/Lifestyle Medicine at Loma Linda University and has contributed to national education in lifestyle medicine. She also co-hosts the Autoimmune Alchemy podcast with Dr. Micah Yu and leads the Integrative Mental Health Summit, bringing root-cause strategies for anxiety, mood, and brain health to a wider audience. Her approach blends diagnostics and conventional care with nutrition, sleep, movement, stress tools, and community to help patients reduce inflammation and build long-term resilience.

In this episode, Dr. Micah Yu welcomes Dr. Nisha Manek, integrative rheumatologist and author of Bridging Science and Spirit, for a wide-ranging conversation on where medicine is headed and why energy, the biofield, and conscious self-care belong beside conventional treatment. 

Hear how immune dysregulation shows up across the body, why drugs alone rarely create remission, and how subtle-energy practices, fascia and meridian science, sleep, intention, and community can help people with autoimmune disease feel better and do more. 

Key takeaways

• What “biofield” means in plain language, how it relates to meridians, fascia, and whole-body connectivity, and why energy is a missing “vital sign” in clinic
• Why rising autoimmune rates suggest we need more than medications alone, and how subtle-energy work can complement standard care to move patients toward remission
• Practical self-regulation: simple hand “circuit” placements to recharge, gentle movement such as tai chi or qigong, sleep, nutrition basics, and intention setting
• A clinician’s perspective on research limits for energy medicine and how physics concepts help translate ancient ideas into modern practice
• Patient empowerment: build your plan with your doctor, add safe energy practices, and lean on community to reduce overload and stick with healing habits

Suggested chapters

[00:00] Intro and guest background

[02:00] From conventional training to integrative practice

[05:00] Autoimmunity on the rise and environmental triggers

[08:00] Beyond drugs: energy as the “missing mechanism”

[11:00] The biofield as a vital sign

[13:00] Meridians, chi, chakras, and a physics “umbrella”

[15:00] Fascia as the body’s connective highway

[20:00] A simple at-home hand circuit to recharge

[29:30] The qigong headache story and what it implies

[36:00] Medicine catching up, clinician burnout, patient agency

[39:00] Where to find Dr. Manek and programs

Autoimmune care improves when we pair smart conventional treatment with practices that restore the body’s energy and calm the nervous system. Start where you are: sleep, nutrition, gentle movement, and a simple daily recharge practice. Use your medical team for diagnostics and safety, then add community for support and momentum. The goal is not perfection. It is steady, sustainable progress toward remission and a fuller life.

Guest resources

• Dr. Manek’s Website: https://www.nishamanekmd.com/
• Get Dr. Manek’s Book: Bridging Science and Spirit: https://www.nishamanekmd.com/book

Host Bio:

Dr. Micah Yu is a board-certified integrative rheumatologist who blends conventional care with lifestyle and nutrition to help people reverse inflammation and live well with autoimmune disease. He is board certified in rheumatology, internal medicine, and lifestyle medicine, completed his residency and rheumatology fellowship at Loma Linda University, and earned his MD from Chicago Medical School along with master’s degrees in biomedical sciences and health care administration.

He also completed fellowship training in integrative medicine at the University of Arizona. Dr. Yu co-founded Dr. Lifestyle in Newport Beach, California, where he sees patients locally and via telemedicine. He also co-hosts the Autoimmune Alchemy podcast with Dr. Melissa Mondala, bringing evidence, empathy, and practical tools to a global audience. His clinical perspective is informed by his own journey with autoimmune disease and by the results he has seen when patients pair targeted therapies with nutrition, sleep, movement, and stress resilience.

Website: https://myautoimmunemd.com/

Dr. Ni-Cheng Liang, a board-certified integrative pulmonologist, shares her journey of being diagnosed with aggressive breast cancer at age 31 during pulmonary critical care fellowship.

She combined clinical trials with acupuncture, traditional Chinese medicine, yoga, and Reiki to survive and thrive through five months of chemotherapy and three surgeries.

We explore how mindfulness (6,000+ published studies) changes stress response at the genetic level, her work supporting burned-out healthcare professionals through the Mindful Healthcare Collective, and evidence-based treatments for long COVID including graded exercise for POTS and post-exertional malaise.

1. Integrative (evidence-based) ≠ alternative (unproven/dangerous)
2. Mindfulness = present moment awareness without judgment
3. 6,000+ studies prove mindfulness works at genetic level
4. Long COVID is multi-systemic and underdiagnosed
5. Anti-inflammatory diet: 5-9 servings vegetables/fruits daily
6. Graded exercise for long COVID: 5 min recumbent, increase 1-2 min weekly
7. Avoid upright exercise with POTS/post-exertional malaise
8. Group movement in nature = community + exercise + healing
9. Chair yoga accessible for bedbound patients
10. Mindfulness practice: anytime, anywhere, doing anything

02:00 Integrative Modalities During Chemotherapy

04:00 Evidence-Based vs. Alternative Therapies

10:00 What Is Mindfulness? Science & Practice

14:00 Mindfulness Changes Stress at Genetic Level

18:00 Mindful Healthcare Collective & Burnout

21:00 Long COVID: Multi-System Effects

24:00 Anti-Inflammatory Diet & Movement

26:00 Dragon Boat Racing: Community Healing

30:00 Resources & Where to Find Dr. Liang

Dr. Ni-Cheng Liang, MD

Board-Certified Integrative Pulmonologist, Cancer Survivor & Mindfulness Teacher

Credentials:

1. Pulmonary & Critical Care Medicine
2. Fellowship, University of Arizona Integrative Medicine
3. Former Executive Director, UCSD Center for Mindfulness
4. Co-Host, Healing Medicine Podcast
5. Founder, Mindful Healthcare Collective
6. 14+ year breast cancer survivor
7. Co-Captain, Team Survivor San Diego dragon boat team

Specializations: Long COVID, mindfulness-based stress reduction, asthma, COPD, cancer survivorship, healthcare burnout, graded exercise for POTS

Website: awakenbreath.org (free meditations)

Podcast: Healing Medicine Podcast

Practice: Coastal Pulmonary Associates (coastalpulmonaryassociates.com)

Serving: California telemedicine available

Free Resources:

1. UCSD Center for Mindfulness audio library
2. Mindful.org magazine
3. Silver Age Yoga (silverageyoga.org) - chair yoga

Dr. Micah Yu, DC, CFMP

Functional Medicine Practitioner & Host of AutoImmune Alchemy

Dr. Micah Yu is a doctor of chiropractic and certified functional medicine practitioner specializing in autoimmune conditions and chronic illness. He recognizes mold exposure as a common root cause of autoimmune disease, particularly in patients with long-haul COVID who suddenly develop mold sensitivities. Dr. Yu is passionate about educating his community on environmental toxins and bringing expert voices like John Banta to help patients understand the hidden triggers affecting their health. He practices integrative medicine with his wife, creating a dynamic team dedicated to uncovering root causes and supporting patients on their healing journey.

Mission: Blending science with soul to transform autoimmune struggles into healing alchemy

AutoImmune Alchemy is a podcast dedicated to the autoimmune community, offering hope, validation, and evidence-based solutions for those struggling with complex chronic conditions.

Hosted by Dr. Micah Yu, the show explores root causes like mold exposure, infections, and environmental toxins that traditional medicine often overlooks. Each episode features expert interviews and cutting-edge treatments to help listeners understand the "why" behind their illness and find pathways to healing.

Connect with AutoImmune Alchemy:

1. Website: MyautoimmunemdHome – New
2. Instagram: @myautoimmunemd
3. Facebook: @MYAutoimmuneMD
4. YouTube: @myautoimmunemd
5. Email: contact@myautoimmunemd.com

Subscribe & Review: Available on Apple Podcasts, Spotify, and all major podcast platforms. If this episode helped you understand mold's role in chronic illness, please leave a 5-star review!

This episode is for educational purposes only and does not constitute medical advice. Always consult with your qualified healthcare provider before starting any new treatment or remediation. Individual results may vary.

In this episode, I sit down with Maria Lloyd, a licensed marriage and family therapist specializing in trauma-informed therapy and ketamine-assisted psychotherapy, to explore how unresolved trauma lives in the body and manifests as autoimmune disease, particularly in highly sensitive people (HSPs) who make up 20% of the population.

Maria shares her personal journey with her son's gut issues and mold exposure that led to complete dysfunction until they addressed both the physical detoxification and mental health trauma through ketamine-assisted psychotherapy, ultimately leading to his full healing and return to college.

We discuss how narcissistic relationships create constant fight-or-flight stress that directly impacts the nervous system and gut health, why turning toward pain with compassion (rather than running from it) calms both emotional and physical symptoms, and how creating secure attachments through therapy can rewire dysregulated nervous systems formed in childhood.

1. 20% of people are highly sensitive (HSPs) - understanding this trait reduces shame and helps create supportive lifestyles
2. Trauma lives in the body; turning toward pain with compassion calms both emotional and physical symptoms
3. Mold exposure can be like "pouring gasoline on the fire" for those with gut issues and mental health challenges
4. Ketamine-assisted psychotherapy works at a somatic level, helping people reconnect with their bodies and feel safe
5. Early childhood attachment patterns affect nervous system regulation and autoimmune disease risk
6. Narcissistic relationships cause constant fight-or-flight stress that directly impacts gut health and autoimmunity
7. Health dramatically improves when people leave narcissistic relationships or set firm boundaries
8. Morning and evening routines (walking, yoga, Qigong, Tai Chi, breath work) create nervous system stability
9. Research shows Qigong and yoga reduce pain and flares in lupus, rheumatoid arthritis, and fibromyalgia
10. It's through relationships that we heal - secure attachments with therapists can rewire dysregulated nervous systems

Chapters & Timestamps

00:00 Welcome: Maria Lloyd & Trauma-Informed Therapy

02:00 Maria's Personal Journey: Her Son's Gut Issues & Mold Exposure

03:00 When the Medical System Failed: The Natural Health Journey

03:30 Mold Detoxification, Diet Changes & Ketamine-Assisted Psychotherapy

04:00 The Holistic Approach: Everything Is Connected

04:30 Navigating Pain Cycles & Hypervigilance in Autoimmune Flares

05:00 Trauma Lives in the Body: Turning Toward Pain with Compassion

06:00 Creating Secure Attachment with Ourselves

07:00 Attachment Styles & Their Impact on Nervous System Regulation

08:00 How Early Childhood Attachment Affects the Brain & Body

09:00 Two Autoimmune Phenotypes: Type A Perfectionists & Highly Sensitive People

10:00 What Are HSPs? 20% of People Are Highly Sensitive

11:00 HSPs Without Attachment: Mental Health & Autoimmune Disease

12:00 Reframing the Mindset: Creating Safety & Boundaries

12:30 Morning & Evening Routines: Walking, Yoga, Qigong, Tai Chi

13:00 Breath Work & Meditation for Autoimmune & Mental Health

13:30 Research on Qigong & Yoga Reducing Pain in Lupus, RA & Fibromyalgia

14:00 Ketamine-Assisted Psychotherapy: A Blowtorch for Getting Unstuck

15:00 Narcissistic Relationships: The Toxic Impact on the Nervous System

16:00 Gaslighting, Shame & Confusion: Setting Boundaries or Leaving

16:30 Health Improves When Leaving Narcissistic Relationships

17:00 Finding Maria: Website, Podcast & Resources

17:30 Closing Thoughts

Maria Lloyd, LMFT

Licensed Marriage & Family Therapist, Trauma Specialist

Credentials & Training:

1. Licensed Marriage and Family Therapist (LMFT)
2. Certified in Ketamine-Assisted Psychotherapy
3. Trauma-informed therapy specialist
4. Attachment science & polyvagal theory expert
5. Somatic therapy practitioner

Specializations:

1. Highly Sensitive People (HSPs) and empaths
2. Trauma resolution and nervous system regulation
3. Narcissistic relationship dynamics (home and workplace)
4. Ketamine-assisted psychotherapy for trauma and autoimmune conditions
5. Attachment-based healing and secure attachment development
6. Somatic therapies for body-based trauma
7. Chronic pain and autoimmune disease with trauma component
8. Complex PTSD and dissociation

Host & Educator:

1. Host of "Catalyst for Healing" podcast
2. Focuses on innovative breakthroughs in mental health
3. Covers ketamine and emerging medicine research
4. Provides newest information on healing modalities

Personal Experience: Maria's journey into holistic health began when her son developed severe gut issues from birth that worsened dramatically after mold exposure in college, leaving him completely unable to function. After the medical system failed to help, she pursued naturopathic approaches including intensive mold detoxification, dietary changes, and ketamine-assisted psychotherapy for the mental health component. Her son's complete healing and return to thriving in college inspired her to integrate these holistic approaches into her therapy practice.

Clinical Approach: Maria emphasizes that trauma lives in the body and must be addressed somatically, not just cognitively. She helps clients turn toward pain with compassion rather than running from it through distraction or addiction. Her approach recognizes that 20% of people are highly sensitive (HSPs) and require different nervous system support than neurotypical individuals. She specializes in helping victims of narcissistic relationships understand the profound impact of constant gaslighting and fight-or-flight stress on physical health, often seeing dramatic health improvements when clients set boundaries or leave toxic relationships. Maria uses attachment science to help clients develop secure attachments with themselves and others, rewiring early childhood attachment wounds through therapeutic relationships.

Website: www.marialloyd.com

Podcast: Catalyst for Healing - www.catalystforhealing.com

Services:

1. Ketamine-assisted psychotherapy
2. Trauma-informed individual therapy
3. Support for highly sensitive people and empaths
4. Narcissistic relationship recovery

In this episode, I sit down with Dr. Trisha Pasricha, a Harvard-trained gastroenterologist who directs the Gut-Brain Research Lab at Beth Israel, to reveal why IBS isn't "all in your head" and how specialized antibody testing can uncover autoimmune attacks on gut neurons. We explore the IBS-fibromyalgia overlap, why one in three people develop IBS after infections, and her groundbreaking research showing smartphone scrolling in bathrooms increases hemorrhoid risk by 46%.

Dr. Pasricha shares evidence-based treatments including peppermint oil and psyllium fiber while debunking probiotic myths, and explains why constipation may be an early Parkinson's warning sign. This conversation validates patients dismissed by doctors and proves these conditions have real pathology requiring collaborative care across specialties.

1. IBS is NOT "all in your head"—pathology lives in the deep enteric nervous system where standard tests can't reach
2. 90% of gut-brain communication flows UPWARD through the vagus nerve, not downward from stress
3. One in three people who get gastroenteritis will develop IBS from "scarring" of gut neurons
4. The Mayo Paraneoplastic Panel can detect autoimmune antibodies attacking gut neurons (specialized test)
5. Many IBS patients also have fibromyalgia—treatments often overlap (SNRIs, peppermint oil, fiber)
6. Psyllium fiber (25g women, 38g men daily) works for BOTH constipation and diarrhea—it's a "shapeshifter"
7. Probiotics are NOT recommended by gastroenterology guidelines—feed your microbiome with fiber and fermented foods instead
8. Smartphone scrolling in the bathroom increases hemorrhoid risk by 46%—limit to 5 minutes maximum
9. Constipation may be an early Parkinson's warning sign—the disease likely begins in the gut
10. H. pylori is abnormally prevalent in Parkinson's patients and treating it can improve tremors by enhancing levodopa absorption

00:00 Introduction to Dr. Trisha Pasricha & Gut-Brain Research

02:00 What Is IBS & Why It's Not "All in Your Head"

04:00 The Enteric Nervous System: Our "Second Brain"

07:00 The Autoimmune Connection to IBS

10:00 IBS-Fibromyalgia Overlap & Treatment Crossover

13:00 Mayo Paraneoplastic Panel: Testing for Autoimmune IBS

16:00 Getting Second Opinions & Finding Neuro-GI Specialists

19:00 Social Media Education: Benefits & Rabbit Holes

21:00 Evidence-Based Treatments: Peppermint Oil & Psyllium Fiber

26:00 The Truth About Probiotics: Not Recommended

29:00 Fiber Diversity & the Mediterranean Diet Connection

33:00 Groundbreaking Research: Smartphones & Hemorrhoids (46% Risk)

36:00 Parkinson's Disease Begins in the Gut

38:00 The GI-Neuro Parkinson's Clinic Model

42:00 H. Pylori Connection to Parkinson's & Rheumatic Diseases

45:00 Post-Infectious IBS & Reactive Arthritis Parallels

47:00 Dr. Pasricha's Book & Where to Find Her

Dr. Trisha S. Pasricha, MD

Board-Certified Gastroenterologist & Neuro-GI Specialist

Credentials & Training:

1. Board Certified in Gastroenterology
2. Harvard Medical School trained
3. Johns Hopkins trained
4. Fellowship in Neuro-Gastroenterology (Gut-Brain Connection & Motility)
5. Director of Gut-Brain Research Lab at Beth Israel Deaconess Medical Center, Boston
6. Medical Columnist, The Washington Post (weekly Monday column)

Research & Publications:

1. Published in New England Journal of Medicine, JAMA, Nature Reviews
2. Leading research on IBS, gut-brain axis, and Parkinson's disease gut origins
3. Groundbreaking studies on smartphone use and GI health
4. Expert in autoimmune causes of GI motility disorders

Specializations:

1. Irritable Bowel Syndrome (IBS) and its autoimmune etiologies
2. Neuro-gastroenterology and enteric nervous system disorders
3. Gut-brain connection and vagus nerve communication
4. Parkinson's disease gastrointestinal manifestations
5. Gastroparesis and GI motility disorders
6. Fibromyalgia-IBS overlap syndrome
7. Post-infectious IBS and reactive gut disorders
8. Joint hypermobility syndromes with GI involvement
9. Interdisciplinary care for complex patients

Author: "You've Been Pooping All Wrong" (Release date: April 7, 2026)

Clinical Philosophy: Dr. Pasricha is passionate about validating patients who've been dismissed with "it's all in your head" and proving that IBS and related conditions have real, measurable pathology in the deep layers of gut tissue that standard tests can't reach. She emphasizes that 90% of gut-brain communication flows upward from the gut through the vagus nerve, not downward from stress, and she takes exhaustive patient histories to uncover triggers like infections, autoimmune connections, or trauma. She strongly advocates for second opinions, encourages social media education (with medical guidance), and believes in treating pain at both the peripheral (gut) and central (brain) levels while being transparent about why certain medications like SNRIs work for pain independent of mental health. Her research lab is pioneering work on how Parkinson's disease may begin in the gut years before motor symptoms appear, and she runs an innovative interdisciplinary clinic with neurologists to treat the whole patient.

Instagram: @trishapasrichamd

Column: The Washington Post (Mondays)

Book: "You've Been Pooping All Wrong" (Available April 7, 2026)

Practice: Beth Israel Deaconess Medical Center, Boston, MA

Note: Due to high demand, securing an appointment may be challenging. Dr. Pasricha recommends finding a neuro-gastroenterologist or motility specialist closer to home who can partner with you on your care journey.

Dr. Micah Yu, DC, CFMP

Functional Medicine Practitioner & Host of AutoImmune Alchemy

Dr. Micah Yu is a doctor of chiropractic and certified functional medicine practitioner specializing in autoimmune conditions and chronic illness. He recognizes mold exposure as a common root cause of autoimmune disease, particularly in patients with long-haul COVID who suddenly develop mold sensitivities. Dr. Yu is passionate about educating his community on environmental toxins and bringing expert voices like John Banta to help patients understand the hidden triggers affecting their health. He practices integrative medicine with his wife, creating a dynamic team dedicated to uncovering root causes and supporting patients on their healing journey.

Mission: Blending science with soul to transform autoimmune struggles into healing alchemy

AutoImmune Alchemy is a podcast dedicated to the autoimmune community, offering hope, validation, and evidence-based solutions for those struggling with complex chronic conditions.

Hosted by Dr. Micah Yu, the show explores root causes like mold exposure, infections, and environmental toxins that traditional...

In this episode, Dr. Melissa Mondala sits down with Dr. Felice Gersh, an integrative OB-GYN, to explore why 80% of all autoimmune patients are women and how our two X chromosomes create a more robust immune system that can become overactive when hormones become imbalanced.

Dr. Gersh explains the fascinating connection between leaky gut, hormonal dysfunction (PCOS, amenorrhea, menopause), and autoimmune diseases like Hashimoto's and rheumatoid arthritis, revealing how molecular mimicry causes antibodies against gut bacteria to cross-react with our own tissues.

They discuss why rheumatologists often miss the root cause by only prescribing biologics that block immune responses without addressing leaky gut and hormone imbalances, and how early intervention with nutrition, stress management, sleep, and hormone balancing can reverse positive ANA antibodies and prevent full-blown autoimmune disease

1. 80% of all autoimmune patients are female due to two X chromosomes with immune-related genes
2. 15% of genes on the "turned off" X chromosome stay active forever—almost all are immune-related
3. Women make more antibodies, have higher white blood cell counts, and mount stronger immune responses
4. Every woman with hormonal dysfunction (PCOS, amenorrhea, menopause) develops gut dysbiosis
5. Leaky gut allows bacteria and toxins to escape, triggering antibody production through molecular mimicry
6. Rheumatoid arthritis is linked to specific gut bacteria leaking through the intestinal barrier
7. Biologics (Humira, Remicade) only block symptoms; they don't fix leaky gut or hormone imbalances
8. Positive ANA = pre-autoimmunity = leaky gut—early intervention can reverse it
9. Vegan diet high in fiber and polyphenols can reduce rheumatoid arthritis pain by 50% in one month
10. Hormone balancing, gut repair, stress management, and nutrition work synergistically—it's all of the above

01:00 Introduction: Dr. Felice Gersh on Women & Autoimmune Disease

01:30 Why Women Have More Robust Immune Systems

02:00 The Two X Chromosomes & Immune-Related Genes

02:30 15% of X Chromosome Genes Stay Active Forever

03:00 Women Make More Antibodies & Have Higher White Blood Counts

04:00 Estradiol & Progesterone's Role in Immune Function

04:30 Leaky Gut, Endotoxins & Gut-Associated Lymphoid Tissue

05:00 PCOS, Amenorrhea & Menopause Always Cause Gut Dysbiosis

06:00 Molecular Mimicry: How Antibodies Attack Your Own Organs

06:30 Hashimoto's: The Most Common Autoimmune Disease in Women

07:00 Rheumatoid Arthritis Linked to Specific Gut Bacteria

08:00 Every Woman with Autoimmune Disease Has Leaky Gut

08:30 Biologics Block Symptoms, Not Root Causes

09:00 The Integrative Approach: Hormones, Gut & Low Dose Naltrexone

09:30 High Cortisol from Stress Causes Leaky Gut

10:00 Fiber, Polyphenols & Nurturing Your Gut Microbiome

10:30 Why Biologics Stop Working After 2-4 Years

11:00 Pre-Autoimmunity: Positive ANA Without Disease Yet

11:30 Reversing Early-Stage Autoimmune Disease

12:00 Terry Wahls: Reversing MS Through Diet & Gut Healing

12:30 Hormone Balancing at Every Life Stage

13:00 Vegan Diet Reduces RA Pain by 50% in One Month

13:30 It's All of the Above: Diet, Hormones & Lifestyle Combined

14:00 Where to Find Dr. Gersh: YouTube, Instagram & Her Practice

15:00 Closing & Resources

Dr. Felice Gersh, MD, FACOG

Integrative OB-GYN & Women's Health Expert

Credentials & Training:

1. Board-certified OB-GYN (FACOG)
2. Fellowship-trained in Integrative Medicine
3. Combines traditional obstetrics/gynecology with functional and metabolic medicine
4. Practices at Integrative Medical Group of Irvine, California

Specializations:

1. Women's hormonal health across all life stages
2. Autoimmune disease prevention and reversal in women
3. Leaky gut and gut microbiome restoration
4. PCOS (Polycystic Ovary Syndrome)
5. Menopause and hormone replacement therapy
6. Integrative approaches to rheumatoid arthritis and Hashimoto's
7. Pre-autoimmunity intervention (positive ANA)
8. Lifestyle medicine for chronic disease reversal

Author & Educator:

1. Multiple published books on women's health
2. Active YouTube channel with educational content
3. Strong Instagram presence (@felicegershmd)
4. International speaker on women's health and autoimmunity

Clinical Approach: Dr. Gersh practices "old-fashioned" one-on-one patient care while educating people worldwide through social media platforms. She emphasizes that women's immune systems are fundamentally different from men's due to the X chromosome's immune-related genes, making women more susceptible to autoimmune diseases when hormones become imbalanced. Her approach addresses root causes—leaky gut, gut dysbiosis, hormonal imbalances, stress, sleep, and nutrition—rather than just suppressing immune responses with biologics. She believes in proactive intervention at the pre-autoimmunity stage (positive ANA) and has successfully reversed early-stage autoimmune diseases through comprehensive lifestyle and hormonal optimization.

Practice: Integrative Medical Group of Irvine

Location: Irvine, California

Social Media:

Instagram: @felicegershmd

YouTube: @FeliceGershMD (active educational channel)

Website: https://integrativemgi.com/

Services:

1. One-on-one patient consultations
2. Educational content on women's health and autoimmunity
3. Resources and freebies available through her platforms

Dr. Micah Yu, DC, CFMP

Functional Medicine Practitioner & Host of AutoImmune Alchemy

Dr. Micah Yu is a doctor of chiropractic and certified functional medicine practitioner specializing in autoimmune conditions and chronic illness. He recognizes mold exposure as a common root cause of autoimmune disease, particularly in patients with long-haul COVID who suddenly develop mold sensitivities. Dr. Yu is passionate about educating his community on environmental toxins and bringing expert voices like John Banta to help patients understand the hidden triggers affecting their health. He practices integrative medicine with his wife, creating a dynamic team dedicated to uncovering root causes and supporting patients on their healing journey.

Mission: Blending science with soul to transform autoimmune struggles into healing alchemy

AutoImmune Alchemy is a podcast dedicated to the autoimmune community, offering hope, validation, and evidence-based solutions for those struggling with complex chronic conditions.

Hosted by Dr. Micah Yu, the show explores root causes like mold exposure, infections, and environmental toxins that traditional medicine often overlooks. Each episode features expert interviews and cutting-edge treatments to help listeners understand the "why" behind their illness and find pathways to healing.

Connect with AutoImmune Alchemy:

In this episode, I sat down with John Banta, a retired certified industrial hygienist with over 35 years of experience, who discovered mold was destroying his wife's health after she recovered completely during a camping trip, leading him to dedicate his career to becoming a "mold doctor" for buildings.

John reveals how 1 in 5 brand new homes has mold before occupation, why killing mold actually makes it produce more biotoxins as a defense mechanism, and his revolutionary microfiber and soapy water technique that actually removes mold instead of spreading it.

We discuss the connection between mold exposure and autoimmune conditions like fibromyalgia and chronic fatigue, how COVID-19 can trigger mold sensitivity in 24% of the population with HLA-positive genetics, and his groundbreaking pathways testing method to find hidden mold using peptide bonds.

1. If you smell mold, it's actively growing - mold only produces musty odors when wet
2. 1 in 5 brand new homes has mold before occupation due to construction practices
3. You can't see mold until there are 1-10 million colony-forming units per square inch
4. Never kill mold - it fights back by producing more biotoxins as a defense mechanism
5. Soapy water (5 drops detergent in a quart) + microfiber cloths remove mold effectively
6. Vinegar doesn't work because "oil and vinegar don't mix" - you need detergent to emulsify lipids
7. 24% of people have HLA-positive genetics; COVID-19 can trigger mold sensitivity overnight
8. Concrete slabs take almost a year to lose 90% of moisture - premature building causes mold
9. Dead mold still makes you sick - removal is essential, not just killing it
10. An ounce of prevention: catching mold early can save $45,000+ in remediation costs

00:00 Opening Teaser & Introduction to John Banta

02:00 Where Mold Is Found: Beneficial Uses & Hidden Dangers

03:00 John's Personal Journey: His Wife's Mystery Illness

04:00 The Camping Trip That Changed Everything

05:00 It's Always About the Water

07:00 Mold Syndrome: Why Symptoms Vary So Much

10:00 Medical Schools Don't Teach About Mold & Autoimmunity

12:00 The Lead Poisoning Story & Daughter's Miracle

17:00 How to Determine If Your Home Has Mold

19:00 Clean Room Technology & Microfiber Innovation

23:00 Why Vinegar Doesn't Work & Soapy Water Does

25:00 Never Kill Mold: It Fights Back with Biotoxins

27:00 Hidden Wall Damage: The 32-Foot Leak Case

29:00 1 in 5 New Homes Have Mold Before Occupation

31:00 Concrete Slabs & the Year-Long Drying Problem

34:00 COVID-19 Triggers Mold Sensitivity in 24% of People

37:00 The Seared Steak Problem: Why Dehumidifiers Aren't Enough

40:00 Finding the Right Remediation Company

43:00 The $50,000 Foundation Mistake: Catch It Early

47:00 Mold Controlled Book: 25-Step Program Overview

49:00 Pathways Testing: Finding Hidden Mold with Peptide Bonds

53:00 John's COVID Fixer-Upper Experience

56:00 How COVID Triggered John's Own Mold Illness

58:00 Hope for the Medical Community

59:00 Where to Find John's Book & Consultations

John Banta, CIH (Retired)

Certified Industrial Hygienist & Mold/Water Damage Specialist

Credentials & Experience:

- Over 35 years of experience in indoor environmental consulting

- Retired Certified Industrial Hygienist (CIH)

- Former medical research technician at UC Davis (FDA-certified in good laboratory practices)

- Degree in Environmental Health Sciences

- Mentored studies with East Coast mold experts (New Jersey, Philadelphia)

- Specialized training in water damage, radon, lead, asbestos, and toxic chemicals

- 25+ years as a dedicated mold and water damage specialist

Specializations:

- Water damage assessment and effective drying protocols

- Hidden mold detection in residential and commercial buildings

- Pathways testing using peptide bonds and proteins

- Mold-sensitive patient advocacy (HLA-positive individuals)

- Construction defect analysis (1 in 5 new homes)

- Microfiber cleaning technology for mold removal

- Next-generation sequencing for mold identification

- Post-COVID mold illness recognition and treatment

Author:

"Mold Controlled: Finding, Fixing and Preventing Mold Problems in Buildings" (385 pages)

- 25-step, 5-stage program for homeowners

- 35 years of experience condensed into practical guidance

- Personal stories including his wife's illness and his own COVID-triggered mold sensitivity

- "Essentials boxes" for quick scanning of key information

- Turns readers into their own best expert about their home

Clinical Approach:

John is a self-described "mold doctor for buildings, not people," though he works extensively with medically sensitive patients. His approach recognizes that 24% of the population has HLA-positive genetics that can be triggered by events like COVID-19, leading to mold sensitivity. He emphasizes that killing mold makes it produce more biotoxins as a defense mechanism, and instead advocates for physical removal using soapy water and microfiber technology. John developed the innovative "pathways testing" method to detect hidden mold by measuring peptide bonds and proteins, and consults with patients worldwide through telephone consultations averaging 3-4 hours daily.

Author Website: www.johnbanta.com

Consulting: www.restconenviro.com

Book: "Mold Controlled" - Available wherever books are sold

Services:

- Telephone consultations (3-4 hours daily)

- Pathways testing kits for hidden mold detection

- Educational resources for homeowners and practitioners

- Building assessment and remediation guidance

Micah Yu, MD, MHA, MS, ABOIM, DipABLM, IFMCP

Dr. Micah Yu is a triple board-certified integrative rheumatologist who blends conventional medicine with holistic, nutrition-based healing to treat autoimmune and chronic inflammatory conditions. A patient himself, Dr. Yu brings a deeply personal perspective to his work, having reversed his own autoimmune arthritis through lifestyle and integrative medicine. He is certified in internal medicine, rheumatology, integrative medicine, lifestyle medicine, and functional medicine. As the founder of MyAutoimmuneMD and co-founder of Dr. Lifestyle Clinic, Dr. Yu empowers patients to address the root causes of illness and reclaim their health from the inside out.

Melissa Mondala, MD, MHA, MS, DipABLM

Dr. Melissa Mondala is a dual board-certified physician in Family and Lifestyle Medicine, with advanced training in Integrative Psychiatry and Integrative Medicine. As President of Dr. Lifestyle Clinic in Newport Beach—recognized by UC Irvine as a Public Health Site of Excellence—she pioneers a holistic, patient-centered approach to chronic disease. Dr. Mondala is a nationally recognized Lifestyle Medicine Intensivist, core faculty at Loma Linda University’s Preventive Medicine Department, and a passionate advocate for plant-based nutrition, mental health, and women's wellness. A sought-after speaker and educator, she combines cutting-edge science with deep compassion to empower lasting healing, especially for those silently suffering from autoimmune, mental health, and long COVID conditions. She shares practical inspiration for healthy living and cooking at @drmelissaskitchen.

Mission: Blending science with soul to transform autoimmune struggles into healing alchemy

AutoImmune Alchemy is a podcast dedicated to the autoimmune community, offering hope, validation, and evidence-based solutions for those struggling with complex chronic conditions.

The show explores root causes like mold exposure, infections, and environmental toxins that traditional medicine often overlooks. Each episode features expert interviews and cutting-edge treatments to help listeners understand the "why" behind their...

In this episode, Dr. Melissa Mondala sits down with Dr. Sam Ko, board-certified emergency medicine physician and medical director at Reset Ketamine, to explore how ketamine therapy is helping the 50-70% of autoimmune patients struggling with depression, anxiety, and chronic pain.

They discuss how ketamine resets hypersensitized pain receptors, reduces inflammatory markers like TNF-alpha and IL-6, influences the gut-brain connection, and provides real hope for conditions like fibromyalgia, rheumatoid arthritis, MCAS, and POTS.

Dr. Ko shares success stories, introduces Stellate Ganglion Block (SGB) as a complementary treatment, and reminds us that your struggle is real and there are evidence-based tools to help you reclaim functional living.

1. 50-70% of autoimmune patients experience depression, anxiety, and central sensitization - there's a fascinating connection between autoimmune conditions and mood disorders
2. Ketamine resets hypersensitized pain receptors via NMDA receptors down the spinal cord, making it powerful for central sensitization
3. The central nervous system and enteric nervous system share the same embryological origin (neuro crest), explaining the profound gut-brain connection
4. Ketamine influences the gut microbiome, which in turn affects the central nervous system and mood
5. Extended infusion protocols (80 minutes to 4 hours) are used for chronic pain conditions like fibromyalgia
6. Ketamine reduces inflammatory markers including TNF-alpha, IL-6, and IL-10, helping to "turn down the volume" on overactive immune systems
7. Stellate Ganglion Block (SGB) provides a "hardware reset" for the sympathetic nervous system, complementing ketamine's "software reset"
8. Success is measured in functional improvements - getting out of bed, doing hobbies, walking 5 minutes daily - not running marathons
9. Team-based care is essential, especially for patients on biologics and immunosuppressants - collaboration with rheumatologists and primary care is key
10. Your struggle is real, your body is wise - if a provider doesn't listen, find one who will

00:00 Introduction: Ketamine for Autoimmune Depression, Anxiety & Pain

00:30 The Autoimmune-Mental Health Link: Why 50-70% Experience Both

01:00 Central Sensitization: Resetting Hypersensitized Pain Receptors via NMDA

02:30 Ketamine Beyond the ER: Treating MCAS, POTS & Complex Autoimmune Conditions

03:00 The Gut-Brain Connection: Embryology of Central & Enteric Nervous Systems

04:00 Serotonin in Gut & Brain: Why "Trust Your Gut" Is Literally True

04:30 How Ketamine Influences the Gut Microbiome & Central Nervous System

06:00 Success Stories: Fibromyalgia & Extended Infusion Protocols

07:00 Rheumatoid Arthritis: Visible Reduction in Joint Inflammation

07:30 Reducing Inflammatory Markers: TNF-alpha, IL-6, IL-10

08:30 Mind-Body Connection: Breaking the Cycle of Pain & Rumination

09:30 Stellate Ganglion Block (SGB): Software vs Hardware Reset

11:00 Addressing Autoimmune Fatigue: Realistic Functional Improvements

12:00 The Power of 1%: Micro-Habits & 5-Minute Daily Walks

13:00 What to Expect: Consultations & Finding the Right Fit

14:00 Team-Based Care: Working with Rheumatologists on Biologics

14:30 Safety Protocols: Lab Monitoring & Continuous Vital Signs

16:00 Never Too Early or Late: Hope for Mental Health Struggles

16:30 Validation: Your Struggle Is Real, Trust Your Body

17:30 Finding Providers Who Listen & Building Your Support Team

18:00 Connect with Reset Ketamine & Final Thoughts

This episode is for educational purposes only and does not constitute medical advice. Always consult with your qualified healthcare provider before starting any new treatment. Individual results may vary.

Dr. Sam Ko, MD Board Certified Emergency Medicine Physician & Medical Director at Reset Ketamine

Credentials & Training:

1. Board Certified in Emergency Medicine
2. Medical school training in embryology and the biopsychosocial paradigm
3. Extensive experience in IV ketamine administration in ER settings
4. Specialized training in ketamine therapy for mental health and chronic pain
5. Certified in Stellate Ganglion Block (SGB) procedures

Specializations:

1. IV Ketamine therapy for autoimmune-related depression, anxiety, and PTSD
2. Central sensitization and neuropathic pain syndromes
3. Fibromyalgia and rheumatoid arthritis treatment
4. MCAS (Mast Cell Activation Syndrome) and POTS (Postural Orthostatic Tachycardia Syndrome)
5. Treatment-resistant mental health conditions in autoimmune patients
6. Stellate Ganglion Block for sympathetic nervous system reset
7. Integrative approach to gut-brain-immune axis dysfunction

Clinical Approach: Dr. Ko founded Reset Ketamine with the mission to provide evidence-based ketamine therapy specifically for patients with complex autoimmune conditions who experience overlapping mental health and pain symptoms. His approach recognizes the intimate mind-body connection and addresses both the "software" (neurological patterns through ketamine) and "hardware" (nervous system through SGB) aspects of healing. He emphasizes team-based care, working collaboratively with rheumatologists and primary care physicians to ensure safe, comprehensive treatment for patients on biologics and immunosuppressants. Dr. Ko works alongside his wife and partner, Dr. Kim, who handles social media and patient education, creating a family-centered practice dedicated to spreading knowledge about innovative treatment options.

Website: www.resetketamine.com

Location: Palm Springs, California

Social Media:

1. Instagram: @resetketamine
2. YouTube: Reset Ketamine (500+ educational videos)
3. LinkedIn: linkedin.com/in/samkomdmba
4. TikTok: @resetketamine
5. Twitter: @resetketamine
6. Pinterest: Reset Ketamine

Dr. Micah Yu, DC, CFMP

Functional Medicine Practitioner & Co-Host of AutoImmune Alchemy

Dr. Micah Yu is a doctor of chiropractic and certified functional medicine practitioner specializing in autoimmune conditions. Alongside his wife Dr. Melissa Mondala, he co-hosts the AutoImmune Alchemy podcast where they blend science with soul to help patients navigate complex autoimmune journeys. Dr. Yu is passionate about integrative approaches to healing and bringing expert voices to the autoimmune community.

Dr. Melissa Mondala

Co-Host of AutoImmune Alchemy

Dr. Melissa Mondala co-hosts AutoImmune Alchemy with her husband Dr. Micah Yu, creating a dynamic duo dedicated to supporting patients and families dealing with autoimmune disease. Together, they work as a team to normalize symptoms, create safe spaces for healing, and bring experienced experts in...

In Part 2 of this Autoimmune Alchemy conversation, Dr.

Micah Yu is joined again by Dr. Robin Rose — family medicine physician, peptide specialist, and kidney health educator — to move from awareness into actionable healing strategies.

This episode dives deep into peptides, bio-regulator therapies, and lifestyle foundations that support kidney repair in autoimmune disease. Dr. Rose explains how autoimmune inflammation damages kidney tubules, blood vessels, and mitochondria, and how targeted tools can help reverse epigenetic injury rather than simply slow decline.

TimeStamps

[0:00] — Part 2 Kickoff: Strategies, Peptides & Bio-Regulators

[1:00] — “Renal Vulnerability Syndrome”: Autoimmune Impact on Kidneys (Quick Review)

[3:00] — Anti-Inflammatory Diet for Kidney Protection: Polyphenols, Herbs, Teas, Toxins

[9:00] — Protein, Carnivore Diets & Why Kidney Nutrition Must Be Personalized

[12:00] — Sugar, Glycotoxins, Gluten/Grains & Practical Kidney-Friendly Protein Choices

[19:00] — Peptides vs Bio-Regulators: What They Are + Epigenetics Explained

[28:00] — Core Support Stack: Nutrients, Sleep/Circadian (Pineal), Carnosine + Clean Labels

[35:00] — Best Peptides/Bio-Regulators for CKD & Autoimmunity + Sequencing + Wrap/Resources

[45:00] — Where to Find Dr. Rose + Closing

Key Takeaways

1. Understand how autoimmune inflammation creates “renal vulnerability syndrome,” quietly damaging kidney tubules and mitochondria.
2. Discover why kidney decline is largely an epigenetic injury — and how that means it can be modulated and improved.
3. Learn the difference between peptides and bio-regulators, and why bio-regulators can directly influence gene expression.
4. Explore anti-inflammatory nutrition strategies that protect kidneys, including polyphenols, herbs, teas, and cooking methods.

In Part 2, Dr. Robin Rose reframes kidney disease not as a fixed diagnosis, but as a dynamic, modifiable process shaped by immune signaling, epigenetics, lifestyle, and targeted therapies. By combining peptides, bio-regulators, nutrition, and mindset, she offers a compassionate and science-based approach to healing that empowers patients rather than frightening them. This episode reminds us that recovery is not about perfection — it’s about informed, consistent choices that restore balance over time.

In this episode of Autoimmune Alchemy, Dr. Micah Yu sits down with Dr. Robin Rose — family medicine physician, peptide specialist, and kidney health educator — to uncover a critical but often overlooked topic: early kidney decline in autoimmune disease.

Dr. Rose shares her powerful personal story of surviving kidney cancer, losing a kidney, and reversing what doctors told her was irreversible kidney failure. She explains why kidney damage often begins long before standard labs change, how autoimmune inflammation quietly stresses kidney tubules, blood vessels, and mitochondria, and why many patients are told to “wait” instead of act.

This conversation reframes kidney health as something proactive, reversible, and deeply connected to autoimmune disease, gut health, lifestyle, peptides, and mindset — offering hope and actionable insight for patients at every stage.

TimeStamps

[0:00] — Introduction: Autoimmune Disease & the Forgotten Role of the Kidneys

[1:20] — Dr. Robin Rose’s Story

[7:40] — Why Kidney Damage Starts Before Labs Change

[11:35] — How Autoimmune Disease Stresses Kidney Tubules, Blood Vessels & Mitochondria

[17:17] — Diet, Protein, Acidity & Lifestyle Choices That Impact Kidney Health

[25:20] — The Gut–Kidney–Immune Axis: Dysbiosis, Uremic Toxins & Inflammation

[31:00] — Early Detection Tools, Binders & Proactive Kidney Protection

[50:00] — Hope, Mindset & Setting the Stage for Part 2 (Peptides & Therapies)

Key Takeaways

• Discover why autoimmune disease creates kidney vulnerability long before creatinine or GFR appear abnormal.
• Understand how inflammation, immune complexes, and vascular damage quietly stress kidney tubules and blood vessels.
• Learn why early kidney decline is often missed — and why waiting for “bad labs” delays prevention.
• Uncover the difference between kidney filtration (glomeruli) and reabsorption (tubules), and why tubules are damaged first.
• Explore how autoimmune conditions like lupus, Sjögren’s, RA, MS, and Hashimoto’s increase renal risk through inflammation and dysbiosis.

Dr. Robin Rose’s story challenges the belief that kidney decline is inevitable. By understanding early warning signs, supporting the gut–immune–kidney axis, and shifting from fear to informed action, patients with autoimmune disease can protect their kidneys long before crisis occurs. Part 1 offers clarity, empowerment, and hope — reminding us that prevention begins with awareness and belief in healing.

In this episode, I sit down with Dr. Amir Esparza, double board-certified colorectal surgeon at City of Hope, to discuss the alarming rise of colorectal cancer in patients under 45—becoming the #1 cause of cancer death in young adults.

Dr. Esparza reveals warning signs often dismissed as hemorrhoids, explains why 30% of rectal cancer patients can avoid surgery through chemo/radiation alone, and shares robotic surgery breakthroughs reducing hospital stays from 7-10 days to 1-2 days.

We discuss fiber's power (30g daily), why 90% of Americans are constipated, gut microbiome's impact on mood and immunity, and City of Hope's integrative approach combining surgery with acupuncture and multi-faith spiritual care.

Key Takeaways

1. Colorectal cancer becoming #1 young adult cancer death by 2030 (20% under 45)
2. Start screening at 45 (or 10 years before family member's diagnosis)
3. Warning signs: rectal bleeding, weight loss, stool changes, pain
4. <20% diagnosed during screening—most symptomatic when found
5. 30% rectal cancer patients avoid surgery with chemo/radiation
6. Robotic surgery: 7-10 days → 1-2 days hospital stay
7. Fiber: 30g daily prevents constipation, diverticulitis, cancer
8. 90% Americans constipated—fiber changes microbiome in 3-4 weeks
9. Gut microbiome (3-4 lbs) impacts mood, sleep, immunity, blood sugar
10. Core activation during weightlifting prevents hemorrhoids
11. 
    

Chapters & Timestamps

02:00 Early Warning Signs Often Dismissed

04:00 Less Than 20% Diagnosed During Screening

05:00 30% Avoid Surgery with Chemo/Radiation

07:00 Robotic Surgery: 1-2 Day Hospital Stays

09:00 When to Get Screened: Age 45 & Family History

14:00 Diverticulitis Prevention Through Fiber

16:00 Why 30 Grams Daily Fiber Changes Everything

20:00 Seeds & Nuts Don't Cause Diverticulitis (Myth)

24:00 Gut Microbiome Controls Mood, Sleep & Immunity

26:00 90% of Americans Are Constipated

34:00 Best Fiber Sources: Avocados, Chia, Berries

42:00 Bloating & Food Intolerances

45:00 Hemorrhoid Treatment: Office vs Surgery

52:00 Core Activation Prevents Hemorrhoids

56:00 City of Hope's Integrative Medicine

Guest Details

Amir Esparza, MD, FACS — Colorectal & General Surgeon

Credentials: Double board-certified. Administrative Chief Resident, University of Illinois Chicago. Outstanding Resident Leadership Award. City of Hope Orange County.

Specializations: Robotic & minimally invasive colorectal cancer surgery, perianal disease, fecal incontinence, diverticulitis, hemorrhoids. Research: remote surgical techniques.

Philosophy: Compassionate care transforms lives. Combines precision surgery with integrative medicine (acupuncture, yoga, meditation, multi-faith spiritual care).

Connect:

Instagram: @dr.amiresparza

YouTube: @dramiresparza

LinkedIn: dramiresparza

Dr. Micah Yu, DC, CFMP

Functional Medicine Practitioner & Host of AutoImmune Alchemy

Dr. Micah Yu is a doctor of chiropractic and certified functional medicine practitioner specializing in autoimmune conditions and chronic illness. He recognizes mold exposure as a common root cause of autoimmune disease, particularly in patients with long-haul COVID who suddenly develop mold sensitivities. Dr. Yu is passionate about educating his community on environmental toxins and bringing expert voices like John Banta to help patients understand the hidden triggers affecting their health. He practices integrative medicine with his wife, creating a dynamic team dedicated to uncovering root causes and supporting patients on their healing journey.

Melissa Mondala, MD, MHA, MS, DipABLM

Dr. Melissa Mondala is a dual board-certified physician in Family and Lifestyle Medicine, with advanced training in Integrative Psychiatry and Integrative Medicine. As President of Dr. Lifestyle Clinic in Newport Beach—recognized by UC Irvine as a Public Health Site of Excellence—she pioneers a holistic, patient-centered approach to chronic disease. Dr. Mondala is a nationally recognized Lifestyle Medicine Intensivist, core faculty at Loma Linda University’s Preventive Medicine Department, and a passionate advocate for plant-based nutrition, mental health, and women's wellness. A sought-after speaker and educator, she combines cutting-edge science with deep compassion to empower lasting healing, especially for those silently suffering from autoimmune, mental health, and long COVID conditions. She shares practical inspiration for healthy living and cooking at @drmelissaskitchen.

Mission: Blending science with soul to transform autoimmune struggles into healing alchemy

AutoImmune Alchemy is a podcast dedicated to the autoimmune community, offering hope, validation, and evidence-based solutions for those struggling with complex chronic conditions.

Hosted by Dr. Micah Yu, the show explores root causes like mold exposure, infections, and environmental toxins that traditional medicine often overlooks. Each episode features expert interviews and cutting-edge treatments to help listeners understand the "why" behind their illness and find pathways to healing.

Connect with AutoImmune Alchemy:

1. Website: MyautoimmunemdHome – New
2. Instagram: @myautoimmunemd
3. Facebook: @MYAutoimmuneMD
4. YouTube: @myautoimmunemd
5. Email: contact@myautoimmunemd.com

Subscribe & Review: Available on Apple Podcasts, Spotify, and all major podcast platforms. If this episode helped you understand mold's role in chronic illness, please leave a 5-star review!

This episode is for educational purposes only and does not constitute medical advice. Always consult with your qualified healthcare provider before starting any new treatment or remediation. Individual results may vary.

Amy Suto, former Hollywood TV writer and bestselling author, shares her incredible RA remission journey—going from debilitating joint pain and hair loss on methotrexate to being completely medication-free for 2 years. She reveals how she refused injectable biologics, discovered American food triggered flares while Italian pizza didn't, and combined Rinvoq with glutathione patches, vitamin D, and toxin detox to achieve remission. Her current protocol: strength training 3x/week, Zone 2 cardio, mostly vegetarian diet, no alcohol, and vegetable juicing—proving RA remission is possible.

1. RA remission without biologics possible—2 years medication-free
2. American food triggered flares; Italian pizza/pasta didn't
3. Glutathione patches detoxed heavy toxin load
4. Vitamin D deficiency common in RA—fixing reduces inflammation
5. Combining Rinvoq with holistic approach accelerated remission
6. Strength training 3x/week + Zone 2 cardio 4x/week critical
7. Quit alcohol, reduced sugar, mostly vegetarian essential
8. Vegetable juicing reduces inflammation flares
9. Mindset: believing remission possible is first step
10. Targeted approach better than 30 supplements

01:00 Diagnosis 2021: Joint Pain & Typing Struggles

02:00 Methotrexate: Hair Loss & Side Effects

03:00 Refusing Injectable Biologics

06:00 Italy Changed Everything: Pizza Helped RA

08:00 Switching to Rinvoq & Holistic Protocol

09:00 Glutathione Patches for Toxin Load

11:00 Vitamin D Deficiency Game-Changer

13:00 Going Off Rinvoq in Argentina

14:00 2 Years Medication-Free & Pain-Free

18:00 Current Protocol: Strength Training & Zone 2

20:00 Vegetable Juicing & No Alcohol

24:00 Mindset: Believing Remission Is Possible

26:00 Where to Find Amy

Amy Suto — Writer, Author & RA Remission Success

Background: Former Hollywood TV writer, bestselling author. Creator of top 25 Substack Make Writing Your Job (30K+ subscribers). Author of Write for Money and Power, Six-Figure Freelance Writer, The Ash Trials.

RA Journey: Diagnosed 2021. Medication-free 2 years. Protocol: glutathione patches, vitamin D, strength training 3x/week, Zone 2 cardio 4x/45min, mostly vegetarian, no alcohol.

Connect:

1. Website:AmySuto.com
2. Substacks: MakeWritingYourJob.com & SutoScience.com
3. Social: @sutoscience (all platforms)

About Your Hosts:

Micah Yu, MD, MHA, MS, ABOIM, DipABLM, IFMCP

Dr. Micah Yu is a triple board-certified integrative rheumatologist who blends conventional medicine with holistic, nutrition-based healing to treat autoimmune and chronic inflammatory conditions. A patient himself, Dr. Yu brings a deeply personal perspective to his work, having reversed his own autoimmune arthritis through lifestyle and integrative medicine. He is certified in internal medicine, rheumatology, integrative medicine, lifestyle medicine, and functional medicine. As the founder of MyAutoimmuneMD and co-founder of Dr. Lifestyle Clinic, Dr. Yu empowers patients to address the root causes of illness and reclaim their health from the inside out.

Melissa Mondala, MD, MHA, MS, DipABLM

Dr. Melissa Mondala is a dual board-certified physician in Family and Lifestyle Medicine, with advanced training in Integrative Psychiatry and Integrative Medicine. As President of Dr. Lifestyle Clinic in Newport Beach—recognized by UC Irvine as a Public Health Site of Excellence—she pioneers a holistic, patient-centered approach to chronic disease. Dr. Mondala is a nationally recognized Lifestyle Medicine Intensivist, core faculty at Loma Linda University’s Preventive Medicine Department, and a passionate advocate for plant-based nutrition, mental health, and women's wellness. A sought-after speaker and educator, she combines cutting-edge science with deep compassion to empower lasting healing, especially for those silently suffering from autoimmune, mental health, and long COVID conditions. She shares practical inspiration for healthy living and cooking at @drmelissaskitchen.

About AutoImmune Alchemy Podcast

Mission: Blending science with soul to transform autoimmune struggles into healing alchemy

AutoImmune Alchemy is a podcast dedicated to the autoimmune community, offering hope, validation, and evidence-based solutions for those struggling with complex autoimmune conditions. Hosted by the dynamic duo Dr. Melissa Mondala and Dr. Micah Yu, the show features expert interviews exploring root causes like hormonal imbalances, leaky gut, and inflammation that traditional medicine often overlooks. Each episode empowers listeners to take proactive control of their health through lifestyle medicine, nutrition, and integrative approaches.

Connect with AutoImmune Alchemy:

Website: MyautoimmunemdHome – New

Instagram: @myautoimmunemd

Facebook: @MYAutoimmuneMD

YouTube: @myautoimmunemd

Email: contact@myautoimmunemd.com

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This episode is for educational purposes only and does not constitute medical advice. Always consult with your qualified healthcare provider before starting any new treatment or making changes to your hormone therapy. Individual results may vary.