Explore every episode of the podcast Antibuddies
| Title | Pub. Date | Duration | |
|---|---|---|---|
| Monolog 20 - The Fountain of IL-11 Youth | 07 Oct 2024 | 00:10:51 | |
In this monolog, Casey discusses a 2024 article about the increase in health and lifespan in mammals after IL-11 inhibition. | |||
| Monolog 19 - Term vs Pre-term immune development | 23 Sep 2024 | 00:11:33 | |
In this monolog, Vijay discusses the difference in immune system development in term and pre-term babies.
Sources: https://pubmed.ncbi.nlm.nih.gov/30142345/ | |||
| Ep27 - The kiss of death | 12 Nov 2023 | 00:28:12 | |
In the 27th episode of our Immunology 101 series, Ash and Jatin talk about how cytotoxic T cells deliver the kiss of death to their targets. | |||
| Ep26 - Cytotoxic T cells | 21 Oct 2023 | 00:30:26 | |
In the 26th episode of our Immunology 101 series, Ash and Jatin shift gears from humoral immunity to cellular immunity and discuss cytotoxic T cell activation. | |||
| Ep25 - Fc receptors & Antibody isotypes | 10 Sep 2023 | 00:32:42 | |
In the 25th episode of our Immunology 101 series, Koshika and Jatin discuss Fc receptors and Antibody isotypes and relate them to specific effector functions. | |||
| Ep24 - Antibody effector functions | 13 Aug 2023 | 00:22:18 | |
In the 24th episode of our Immunology 101 series, Ash and Jatin discuss the various effector functions of Antibodies | |||
| Ep23 - Somatic hypermutation and Class switching | 15 Jul 2023 | 00:22:42 | |
In the 23rd episode of our Immunology 101 series, Ash, Koshika, and Jatin discuss the events taking place inside the germinal center - class switching and somatic hypermutation. | |||
| Ep22 - B cells in the germinal center | 25 Jun 2023 | 00:29:03 | |
In the 22nd episode of our Immunology 101 series, Ash, Koshika, and Jatin talk about the events of the germinal centers. | |||
| Ep21 - Fate of a B cell | 04 Jun 2023 | 00:40:13 | |
In the 21st episode of our Immunology 101 series, Ash and Jatin talk about the fate of the B cell after it encounters the antigen and how it travels through the various compartments of a secondary lymphoid organ. | |||
| Bep40 - Non-canonical T cell activation in TDLNs | 15 May 2023 | 01:11:43 | |
In this Buddisode, we sit down with Dr. Nataliya Prokhnevska to discuss her work on the fate and role of non-cytotoxic CD8+ T cells found in the tumor-draining lymph nodes of cancer patients. | |||
| Monolog 11 - Neuro-Pancreas Chat | 05 May 2023 | 00:11:59 | |
In this monolog, Vijay talks about a recent article describing the communication between the vagus nerve and the pancreas. | |||
| Ep20 - B cells are mean | 23 Apr 2023 | 00:26:00 | |
In the 20th episode of Immunology 101 series, Ash, Koshika, and Jatin shift gears to talk about B cell activation and draw parallels with T cell activation process. | |||
| Monolog 18 - Interleakin' | 27 Aug 2024 | 00:12:45 | |
In this monolog, Akshat ponders about the spatiotemporal underpinnings of cytokine concentrations in tissue niches...and how it all appears to function like a gossip network. | |||
| Ep19 - Memory T cells | 02 Apr 2023 | 00:28:09 | |
In the 19th episode of the Immunology 101 series, Ash, Koshika, and Jatin talk continue their conversation about T cell subsets with a focus on memory T cells. | |||
| Ep18 - T helper classification and polarization | 26 Mar 2023 | 00:31:06 | |
In the 18th episode of Immunology 101 series, Ash, Koshika, and Jatin talk about classification of T helper cells and their functions. | |||
| Bep39 - How SARS CoV2 aces cytotoxic T cells | 15 Mar 2023 | 01:13:46 | |
In this Buddisode, we sit down with Drs. Cosima T Baldari & Rino Rappuoli to discuss their work on a unique immune evasion strategy deployed by SARS CoV2 to paralyze cytotoxic T cells. | |||
| Ep17 - T cell activation | 05 Feb 2023 | 00:40:11 | |
In the 17th episode of Immunology 101 series, Natalie and Jatin talk about the T cell activation process and make some very lame jokes. | |||
| Monolog 10 - Evolution of Immunity | 27 Dec 2022 | 00:12:20 | |
In this monolog, Natalie talks about the evolutionary history of the immune system. | |||
| Bep38 - Yin and Yang of Tfh | 15 Nov 2022 | 00:50:56 | |
In this Buddisode, we sit down with Dr. Simon Bélanger from the La Jolla Institute of Immunology (currently at Vir Biotechnology) to discuss his work on a transcription factor that can define early T follicular helper cell fate. | |||
| Bep37 - You won't believe what your eosinophils are doing! | 23 Oct 2022 | 00:47:57 | |
In this Buddisode, we sit down with Dr. Emilie Cosway from the Institute of Immunology and Immunotherapy at the University of Birmingham (UK) to discuss her recent paper about the mechanisms behind thymic regeneration. | |||
| Bep36 - IL17A and ICI-induced autoimmune thyroiditis | 29 Sep 2022 | 00:43:32 | |
In this buddisode, we sit down with Dr. Melissa Lechner from the Division of Endocrinology, Diabetes, and Metabolism at the UCLA David Geffen School of Medicine to discuss her recent paper about the mechanisms behind immune checkpoint inhibitor-induced autoimmune thyroiditis. | |||
| Bep35 - Aging affects Central Tolerance | 07 Sep 2022 | 01:02:44 | |
We sit down with Dr. Jessica Lancaster from the Department of Immunology, Mayo clinic to discuss her recent paper about the effect of Aging on Central Tolerance and Treg induction. | |||
| Ep16 - Pathways of the Complement System | 09 Aug 2022 | 00:30:43 | |
In the 16th episode of Immunology 101 series, Natalie and Jatin talk about an undergrad's worst nightmare 2 months into the immunology course - The complement system. | |||
| Monolog 17 - CAR-T and TCR-T Cells Face Off! | 29 Jul 2024 | 00:15:28 | |
In this episode, Akshat outlines the salient features of CAR or TCR-engineered T cells, and deigns to ponder: is one modality just objectively better than the other? | |||
| Bep34 - A tale of labor, pre-term birth, and IL-22 | 21 Jun 2022 | 01:15:17 | |
We sit down with Dr. Nardhy Gomez-Lopez from the Department of Obstetrics and Gynecology at Wayne State University to discuss her recent paper about the role of IL-22 in pregnancy and pre-term births. | |||
| Ep15 - Regulation of Innate Immunity | 21 Apr 2022 | 00:33:09 | |
Natalie and Jatin talk about positive and negative regulation in immune response, how the cells of the innate immunity interact with the adaptive, and the ubiquity of the immune system across phyla. | |||
| Ep14 - Innate Immune Cells | 31 Mar 2022 | 00:28:15 | |
In the 14th episode of Immunology 101 series, Natalie and Jatin talk about the cellular facet of the innate immune system. | |||
| Bep33 - Transgenerational trained immunity | 21 Mar 2022 | 00:52:32 | |
Eugenio and Jatin sit down with Dr. Jorge-Dominguez Andres (Ph.D.) from Radboud University to discuss trained immunity and its transgenerational inheritance in mice. | |||
| Bep32 - 6 shades of NF-kB #2 | 27 Feb 2022 | 00:52:19 | |
We continue our discussion with Dr. Adewunmi Adelaja (M.D., Ph.D.), from the University of California Los Angeles, about NFkB signaling and how signals to different stimuli are relayed inside macrophages. | |||
| Bep31 - 6 shades of NF-kB #1 | 18 Feb 2022 | 00:49:54 | |
We sit down with Dr. Adewunmi Adelaja (M.D., Ph.D.) from the University of California Los Angeles to discuss NFkB signaling and how signals to different stimuli are relayed inside macrophages. | |||
| Monolog 9 - Why do we lose smell after COVID19? | 08 Feb 2022 | 00:08:07 | |
In this monolog, Tanu breaks down a recent study that elucidates the mechanism behind the loss of sense of smell in COVID19 patients. | |||
| Monolog 8 - Neuroimmune interactions | 29 Jan 2022 | 00:09:38 | |
In this monolog, Vijay highlights some of the interactions between the neurons and the immune cells that show an intricately woven neuroimmune network. | |||
| Bep30 - Finding the right clone | 17 Jan 2022 | 00:59:01 | |
We sit down with Dr. Yosuke Kumamoto from Rutgers new jersey medical school to discuss the role of a specific subset of DCs that retain lymphocytes in the SLOs to scan the repertoire post-immunization. | |||
| Monolog 7 - Cancer is an immune disease | 05 Jan 2022 | 00:14:21 | |
In this monolog, Natalie explains how cancer is a disease of the immune system. | |||
| Monolog 15 - The Liver is Bile-lingual | 07 Mar 2024 | 00:16:12 | |
In this Monolog, Akshat discusses how the liver "speaks" both immunity and metabolism via bile to control hepatic tumors. Liver X Receptors also make an appearance. | |||
| Ep13 - Innate immunity and other PRRs | 24 Nov 2021 | 00:34:18 | |
In the 13th episode of Immunology 101 series, Natalie and Jatin continue talking about PRR signaling. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources: Kuby Immunology | |||
| Ep12 - Innate immunity and TLR signaling | 10 Nov 2021 | 00:36:44 | |
In the 12th episode of Immunology 101 series, Natalie and Jatin shift gears to talk about Innate immunity with a focus on TLR signaling. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources: Kuby Immunology | |||
| Monolog 6 - TIM3 and Breast cancer | 26 Oct 2021 | 00:15:22 | |
In this breast cancer awareness month special monolog, Tanu talks about the challenges faced for breast cancer research and finding an effective treatment that works for everyone. | |||
| Ep11 - B cell development in the spleen | 19 Oct 2021 | 00:30:01 | |
Immunology 101 | |||
| Bep29 - Origin of Eukaryotes and the TCA cycle #2 | 02 Oct 2021 | 00:31:27 | |
In the 2nd part of the Origin of Eukaryotes series, Dara and Jatin sit down with Dr. Dylan G Ryan from University of Cambridge (formerly at Trinity College Dublin) to discuss his 2020 perspective article about the role of TCA cycle in Eukaryogenesis. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: TCA cycle signalling and the evolution of eukaryotes (nih.gov)
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| Bep28 - Origin of Eukaryotes and the TCA cycle #1 | 26 Sep 2021 | 00:47:33 | |
In the 1st part of the Origin of Eukaryotes series, Dara and Jatin sit down with Dr. Dylan G Ryan from University of Cambridge (formerly at Trinity College Dublin) to discuss his 2020 perspective article about the role of TCA cycle in Eukaryogenesis. | |||
| Bep27 - Phase separation in Immune Signaling #2 | 21 Sep 2021 | 00:35:26 | |
In the 2nd part of the phase separation series, Eugenio, Natalie, & Jatin sit down with Xiaolei Su, Qian Xiao, and Ceara McAtee continue their discussion. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Phase separation in immune signalling | Nature Reviews Immunology
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| Bep26 - Phase separation in Immune Signaling #1 | 14 Sep 2021 | 00:47:37 | |
In this Buddisode, Eugenio, Natalie, & Jatin sit down with Xiaolei Su, Qian Xiao, and Ceara McAtee from Yale cancer center at Yale university to discuss their latest review article published in Nature Immunology Reviews in July of 2021. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Phase separation in immune signalling | Nature Reviews Immunology
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| Bep25 - Microbe-specific thymocyte development | 30 Aug 2021 | 00:52:32 | |
In this Buddisode, Dara, Eugenio, Natalie, & Jatin sit down with Daniel from Gretchen Diehl's lab at Memorial Sloan Kettering Cancer Center, NY. The discussion entails their 2021 paper about the development of bacteria-specific T cells in the thymus of young mice and all the implications surrounding this discovery. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Thymic development of gut-microbiota-specific T cells | Nature
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| Ep10 - B cell development in the bone marrow | 15 Aug 2021 | 00:35:04 | |
In the 10th episode of Immunology 101 series, Dara, Jatin, and Natalie talk about B cell development in the bone marrow, some key transcription factors involved in the process, and the hardy fractions. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Join us on our bimonthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Sources: 1. Kuby Immunology | |||
| Ep29 - Barrier immunity & the gut | 04 Feb 2024 | 00:21:46 | |
In the 29th episode of our Immunology 101 series, Ash and Tanu start the new year 2024 with a discussion on Barrier Immunity with a focus on the gut. | |||
| Bep24 - Type I vs Type II interferons in autoimmunity | 01 Aug 2021 | 00:48:01 | |
In this Buddisode, Dara & Jatin sit down with Adam Fike from Ziaur Rahman's lab at Penn State University. The discussion entails their 2020 publication that teased apart the contribution of Type I and Type II interferons in TLR7-mediated systemic autoimmunity. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity | The Journal of Immunology (jimmunol.org)
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| Bep23 - B cells in the Brain | 25 Jul 2021 | 01:03:08 | |
In this Buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Wei-le Wang who is a posdoc in the lab of Dr. Marco Colonna lab at Washington University, St. Louis. The discussion entails Wei-le's recent publication that finds a unique niche around the CNS where new immune cells are formed. | |||
| Monolog 5 - Endogenous retroviruses in skin immunity | 18 Jul 2021 | 00:12:46 | |
In this monolog, Tanu talks about the effect of diet, microbiota, and the endogenous retroviral elements in skin inflammation. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: https://www.sciencedirect.com/science/article/abs/pii/S0092867421006504 | |||
| Bep22 - Your immune cells determine how fast you age | 05 Jul 2021 | 01:01:49 | |
In this Buddisode, Eugenio, Natalie, and Jatin sit down with Drs. Rafael Flores and Matthew Yousefzadeh to discuss their recent research that aims to dissect the role of the immune system in systemic aging. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com. Article of discussion: An aged immune system drives senescence and ageing of solid organs | Nature
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