Advances in Care – Details, episodes & analysis

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Advances in Care

NewYork-Presbyterian

Health & Fitness

Science

Education

Frequency: 1 episode/21d. Total Eps: 65

On Advances in Care, epidemiologist and science communicator Erin Welsh sits down with physicians from NewYork-Presbyterian hospital to discuss the details behind cutting-edge research and innovative treatments that are changing the course of medicine. From breakthroughs in genome sequencing to the backstories on life-saving cardiac procedures, the work of these doctors from Columbia & Weill Cornell Medicine is united by a collective mission to shape the future of health care and transform the lives of their patients. Erin Welsh, who also hosts This Podcast Will Kill You, gets to the heart of her guests’ most challenging and inventive medical discoveries. Advances in Care is a show for health careprofessionals and listeners who want to stay at the forefront of the latest medical innovations and research. Tune in to learn more about some of medicine’s greatest leaps forward. For more information visit nyp.org/Advances

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Score global : 79%

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Navigating High-Risk Pregnancy with Multidisciplinary Cardio-Obstetrics Care

Episode 54

Thursday, May 14, 2026 • Duration 17:52

Erin Welsh is joined by Dr. Jennifer Haythe, director of the Adult Pulmonary Hypertension Center and Cardio-Obstetrics programs at NewYork-Presbyterian and Columbia, to discuss the prevalence of high-risk pregnancies due to heart disease and the multi-disciplinary efforts required for optimal patient care.

Many women in the US are having children at a later age than in the past, and with that comes an increased occurrence of certain conditions that create risk for heart disease during, or after, pregnancy. In fact, cardiovascular disease is the leading cause of maternal mortality in the US, with pulmonary hypertension and peripartum cardiomyopathy posing significantly high risks. Dr. Haythe discusses how coordinated, multi-disciplinary care is crucial in treating these vulnerable patients, and how the cardio-obstetrics program at Columbia is approaching care to allow women, many of whom have been told they could never give birth, achieve safe and successful pregnancies. Dr. Haythe also talks about the latest cutting edge research for cardiac conditions in pregnancy and her program’s involvement in the ReBIRTH study, a national, multi-center, randomized placebo controlled trial examining the use of bromocriptine as a course of treatment for pregnant patients with peripartum cardiomyopathy - a study that could potentially introduce a new paradigm in high-risk pregnancy care.

Chapters:

[00:00 - 5:49] Columbia’s Multidisciplinary Cardio-Obstetrics Program

Dr. Haythe and Erin discuss how the multidisciplinary cardio-obstetrics program at Columbia and the growing population of pregnant patients with heart disease.

[05:49 - 10:28 ] Navigating Cardiovascular Complications

Dr. Haythe and Erin talk about the risks of pulmonary hypertension and other cardiovascular complications in pregnant patients, including during the post-partum period, and also highlights new research that may help change the course of treatment.

[10:28 - 14:08] A Rewarding Patient Story

Dr. Haythe tells a story of a pregnant patient with pulmonary hypertension who delivered successfully, demonstrating how the program effectively managed her care.

[14:08 - 17:12 ] Vision For the Future

Dr. Haythe shares her experience as part of the New York City Maternal Mortality Review Board, a committee formed to review maternal deaths and determine how to minimize the risk of recurrence going forward.

[17:12 - 18:04] Credits

***
Jennifer Haythe, MD, is the Director of the Adult Pulmonary Hypertension Center, and the Cardio-Obstetrics program at Columbia. She is currently the Irene and Sidney B. Silverman Associate Professor of Cardiology, Center for Advanced Cardiac Care at Columbia, and Co-Director of The Columbia Women’s Heart Center.

Dr. Haythe specializes in pulmonary hypertension, cardio-obstetrics, heart failure, HFPEF, and cardiovascular disease in women.

For more information visit

nyp.org/Advances

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Redefining Treatment for Chiari Malformation with a Transitional Care Model

Episode 53

Thursday, April 30, 2026 • Duration 19:22

On this episode of Advances in Care, Erin Welsh and Dr. Jeffrey Greenfield, pediatric neurosurgeon at NewYork-Presbyterian and director of the Chiari CARE program at Weill Cornell Medicine, discuss a rare condition called Chiari malformation.

Typically diagnosed by MRI, Chiari malformation is classified when part of the cerebellum descends into the upper spinal canal. Though some of the most severe types of Chiari malformation can be diagnosed during pregnancy, the most common type may present asymptomatically until adolescence or adulthood, with symptoms that are often misdiagnosed as other disorders. To address the unmet need for proper diagnosis and management of this condition, Dr. Greenfield created the Chiari CARE program–a multidisciplinary approach involving neurology, pain management, neuropsychology, radiology, and more–to help provide full-spectrum care to patients. A key factor of the Chiari CARE program is its emphasis on transitional care, which includes both treating patients who come in as pediatrics throughout their adulthood as well as those who are diagnosed later in life.

But Dr. Greenfield’s vision extends to the future. Having just treated the program’s thousandth surgical patient, his team is amassing and analyzing outcomes data and using machine learning to refine predictions for which future patients would be good candidates for surgery or require other treatment methods that will enhance overall quality of life.

Chapters:

[00:00 - 4:12] Chiari CARE

Dr. Greenfield and Erin discuss a rare congenital brain condition called Chiari malformation, and highlight Dr. Greenfield’s Chiari CARE program at NewYork-Presbyterian and Weill Cornell Medicine.

[4:12 - 8:35] The Importance of Transitional Care

Dr. Greenfield expands on the importance of transitional care for patients with congenital neurological conditions like Chiari malformation.

[8:35 - 11:51] Determining the Right Approach

Dr. Greenfield explains how he and his team determine whether their patients need surgery or not, and the challenges of diagnosing and treating Chiari malformation in adults.

Single Port Robotic Surgery Transforms Outcomes for Lung Tumor Removal

Episode 52

Thursday, April 16, 2026 • Duration 17:01

Erin Welsh is joined by Dr. Jeffrey Port, a thoracic surgeon at NewYork-Presbyterian and Weill Cornell Medicine, and a leader in thoracic surgical oncology, to discuss advances in minimally invasive robotic surgery and the unique collaborative care model that his program employs to operate on complex chest tumors.

When Dr. Port first started his career, the surgical techniques used to operate on lung cancer patients were akin to open heart surgery. But in recent years, his team has pioneered new techniques in thoracic surgery, specifically a minimally invasive single port robotic approach, which utilizes a multi-finger robotic hand to operate through one incision. Weill Cornell Medicine is currently one of only 10 centers nationwide using this technology for thoracic surgery, and the highest-volume center in the country that is performing these advanced procedures. Dr. Port also discusses the unique collaborative model his team utilizes to perform complex chest tumor surgeries which oftentimes require cardiopulmonary bypass. This combination of cutting edge surgical techniques, high case volume, and a multidisciplinary approach, is meaningfully expanding treatment options for patients who cannot be treated elsewhere.

Chapters:

[00:00 - 04:39] Introduction to Thoracic Surgery

Dr. Port and Erin discuss the standard of care for thoracic surgery as it stood a few years ago and his pioneering use of robotics in single port thoracic surgery today.

[04:39 - 09:06] Recovery Benefits of Single-Port Robotic Surgery

Dr. Port expands on how the technology differs from standard robotics and the recovery benefits of single-port robotic thoracic surgery.

[09:06 - 13:20] NewYork-Presbyterian/Weill Cornell Medicine as Early Adopter of Innovative Technology

Dr. Port details his department’s efforts as a training facility, teaching surgeons and health care professionals from across the world the techniques and workflows that contribute to their success.

[13:20 - 16:16] Multidisciplinary Approach as a Key to Cardiopulmonary Care

Improving Preterm Birth Outcomes with Virtual Cervix Technology

Episode 51

Thursday, April 2, 2026 • Duration 20:25

On this episode of Advances in Care, host Erin Welsh is joined by Dr. Mirella Mourad, maternal-fetal medicine specialist at NewYork-Presbyterian and co-director of the Preterm Birth Prevention Center at Columbia, to explore a groundbreaking new technology aimed at improving the diagnosis and treatment of preterm birth.

Preterm birth impacts approximately 1 in 10 pregnancies in the United States, making it a leading cause of neonatal complications and long-term health challenges. But despite its prevalence and associated risks, innovative solutions to address the condition have lagged behind. To address this gap, Dr. Mourad and her collaborator, Dr. Kristin Meyers, a professor of mechanical engineering at Columbia’s School of Engineering, are developing a new tool: a patient-specific “digital twin” of the cervix. This advanced technology has the potential to revolutionize obstetric care for patients, by allowing clinicians to test new treatment methods, collect data to better understand why certain people are at risk for preterm birth, and overall, catalyze innovation in the historically under-researched field of maternal-fetal medicine, ultimately helping to drive better outcomes and successful pregnancies. Dr. Mourad also discusses how this digital twin can potentially assist with identifying women with placenta accreta spectrum disorder, and inform more precise and proactive treatment plans for patients with this high-risk condition.

Chapters:

[00:00 - 4:24] The Prevalence of Pre-Term Birth

Dr. Mourad discusses the prevalence of pre-term birth and what drew her to obstetrics.

[4:24 - 8:10] Room for Improvement in Diagnostics and Intervention

Dr. Mourad explains how pre-term birth is currently diagnosed and the limited tools for intervention.

[8:10 - 13:00] The Digital Twin

Dr. Mourad describes the “digital twin,”and how it can be used to simulate a patient’s biomechanics to better predict whether they may have a pre-term birth.

[13:00 - 19:40] Looking Forward

How ECMO Leadership is Driving Improved Survival and Post-ICU Recovery

Episode 50

Thursday, March 19, 2026 • Duration 19:40

On this episode of Advances in Care, Erin Welsh is joined by Dr. Cara Agerstrand, director of the Medical ECMO Program at NewYork-Presbyterian and Columbia, and Dr. Matthew Baldwin, critical care specialist at NewYork-Presbyterian and research lead of Columbia’s Baldwin Lab which focuses on the study of critical illness survivorship.

Thousands of people suffer from cardiopulmonary conditions such as cardiac arrest and severe respiratory illnesses in the United States every year, with many requiring mechanical ventilation and critical care in the ICU. To better serve these patients, NewYork-Presbyterian and Columbia has built a renowned program to manage these patients on rescue therapies like extra-corporeal membrane oxygenation (ECMO), the most advanced form of cardiopulmonary life support. Since 2009, the team at NewYork-Presbyterian and Columbia has established an expertise to care for the sickest respiratory and cardiac failure patients with this technology, and has been at the forefront of utilization which has rapidly evolved from early pediatric use to post H1N1 and COVID surges.

The standards of care for ECMO treatment and patient outcomes set by New York Presbyterian and Columbia over the past decade has earned them recognition as an ELSO Platinum Level Center of Excellence, one of only a few centers worldwide to have consistently achieved this status since it was first awarded. The team takes this expertise further through advanced research in The Baldwin Lab, which focuses on a variety of projects to better understand the biological factors of why some patients fully recover from ICU stays and others do not, as well as physical, mental, and emotional wellbeing for patients.

Chapters:

[00:00 - 4:07] ECMO and Post-Intensive Care Syndrome

Dr. Agerstrand describes advances in ECMO care and Dr. Baldwin outlines his research in post-intensive care syndrome and targeted recovery efforts.

[4:07 - 9:25] Refining ECMO

Dr. Agerstrand discusses how Columbia’s early ECMO adoption positioned them to refine techniques and set a new standard for its use in the ICU.

[9:25 - 14:33] Recovery After Prolonged Critical Care

Phase 3 Trial Reduces Risk of Progression in Metastatic Prostate Cancer

Episode 49

Thursday, March 5, 2026 • Duration 15:54

On this episode of Advances in Care, host Erin Welsh is joined by Dr. Scott Tagawa, medical oncologist at NewYork-Presbyterian and director of the Genitourinary Oncology Program at Weill Cornell Medicine, to talk about the latest developments in prostate cancer care.

Prostate cancer is the most common cancer in men after skin cancer, with 5-10% of patients presenting with metastasis at the time of diagnosis. Advancing treatment options for men with metastatic disease remains a critical priority in oncology. To address this challenge, Dr. Tagawa recently led a promising Phase III randomized trial– called PSMAddition– to assess radioligand therapy, a subset of targeted radionuclide therapy, or TRT. This new therapeutic agent, lutetium PSMA-617, is being tested in men with hormone-sensitive metastatic prostate cancer. Radioligand therapy works by seeking prostate-specific membrane antigens (PSMAs) to deliver radiation to prostate cells throughout the body while minimizing surrounding damage that other therapies can sometimes cause. The results from the PSMAddition trial were significant. The addition of TRT in addition to standard hormone treatment slowed cancer progression by 28%, yielded notable declines in PSA levels, and proved benefits across patient subgroups. The PSMAddition trial is the first to analyze the use of this treatment regimen earlier in care and could potentially redefine the standard of care for patients with metastatic prostate cancer.

While metastatic prostate cancer remains incurable, combination strategies incorporating PSMA-targeted therapy represent a promising pathway for expanding the quality and quantity of life for patients, and may prove beneficial as a first-line treatment.

This breakthrough trial builds on 25 years of innovation in prostate cancer research at NewYork-Presbyterian and Weill Cornell Medicine, where foundational discoveries helped advance the development of PSA and PSMA-targeting agents that are now transforming cancer care.

Chapters:

Breakthrough Technology Improves Concussion Assessment and Player Safety

Episode 48

Thursday, February 19, 2026 • Duration 17:20

On this episode of Advances in Care, host Erin Welsh sits down with Dr. Thomas Bottiglieri, chief of the primary care sports medicine division at NewYork-Presbyterian and Columbia, to discuss the evolving landscape of concussion care– from prevalence to emerging diagnostic breakthroughs.

With over 2 million estimated concussions occurring annually in the United States, and many of them affecting young athletes, Dr. Bottiglieri and his colleagues have sought to develop a more accurate and accessible way to objectively diagnose concussion. While a single injury may not cause long term issues, research shows that repeated head trauma– and lack of proper care– can lead to premature neurodegeneration.

During their research to improve diagnostic measures, Dr. Bottiglieri and his team discovered a biomarker associated with severe concussions: a subtle tremor of the head and neck that becomes amplified when a concussed patient tries to visually focus on a target.

This discovery led to the development of ProScope, an innovative eyetracking software tool that measures head and neck stability and can detect the diagnostic biomarker with over 80% sensitivity. With the advent of these tools, clinicians can now, for the first time, objectively measure concussion. A former competitive athlete himself, Dr. Bottiglieri hopes that the ProScope tool can become commercially available to improve access to cost-effective diagnosis, ensuring that athletes– or anyone with a head injury– can recover safely and return to the activities they love.

Chapters:

[00:00 - 3:09] Improving Concussion Diagnostics

Dr. Bottiglieri shares how his own experience with a sports related concussion informs his approach with patients and motivates him to improve concussion diagnostics.

[3:09 - 8:31] Discovering a Biomarker for Severe Concussion

Dr. Bottiglieri explains how most concussions are diagnosed by patients self-reporting rather than quantifiable clinical signs and how his recent research has identified a new biomarker associated with severe concussions.

2025 Year in Review: Revisiting the Top Takeaways from Advances in Care

Episode 47

Thursday, December 18, 2025 • Duration 19:53

On the final episode of 2025, host Erin Welsh is joined by Courtney Allison, host of NewYork-Presbyterian’s health and wellness podcast, Health Matters, to recap the year’s highlights from their dozens of conversations with clinicians, researchers, and health care specialists from Columbia & Weill Cornell Medicine. They highlight key takeaways, revisit groundbreaking treatments that were pioneered across the institution, and discuss several research updates that are shaping the future of medicine for both physicians and patients.

For more information visit nyp.org/Advances

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Revisiting the Network Effect: Analyzing Brain Structures to Treat Depression

Episode 46

Thursday, December 4, 2025 • Duration 26:55

For any patient diagnosed with depression for the first time, the recommended course of treatment is the same: a medication like a selective serotonin reuptake inhibitor (SSRI), an evidence based psychotherapy, or both. But there is a large group of people for whom these treatments simply won't work. That’s where Dr. Conor Liston and his team focus. In this episode from the Advances in Care archives, Dr. Liston speaks with former host Catherine Price about his work mapping the brain is helping doctors better understand where depression is impacting certain brain structures and what that means for the symptoms patients present. Dr. Liston’s work is focused on identifying how these symptoms impact patients' brains and using those findings to identify the best treatment approach.

Since this episode aired, Dr. Liston and his colleagues have continued to build on their research regarding a specific region of the brain called the “salience network.” They found that the salience network was considerably larger in people with clinical depression than in those without, and that people with larger salience networks in childhood were more likely to develop depression later in life. Their research points to an enlarged salience network as the first objective biomarker for diagnosing depression, which could revolutionize how depression is treated, and allow for intervention even before symptoms develop.

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Revisiting Deep Learner: Building AI to Improve Cardiovascular Care

Episode 45

Thursday, November 13, 2025 • Duration 30:37

In this episode from the Advances in Care archives, Dr. Pierre Elias sits down with Catherine Price to talk about how utilizing technologies like artificial intelligence and machine learning can help diagnose patients even before symptoms develop, and support doctors by freeing them up to focus on providing personalized care to their patients. They discuss navigating bias in both artificial intelligence and clinical care, and how new technology will improve the future of medicine.

Since this episode aired, Dr. Elias and his collaborators expanded their research involving AI and cardiac care, developing tools for detecting mitral regurgitation and heart failure.

Additionally, a team at NewYork-Presbyterian and Columbia used AI as a fertility treatment for azoospermia, and NewYork-Presbyterian deepened its commitment to developing applications of AI in medicine through a $2 billion campaign to invest in talent and technology.

For more information visit nyp.org/Advances

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Advances in Care – Details, episodes & analysis

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Advances in Care – Details, episodes & analysis

Podcast details

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