Explore every episode of the podcast A Functional Approach with Dr. Jim Chialtas

What if I told you I could shed eight pounds, rediscover my defined abs, and significantly improve my blood markers in just five weeks? It sounds like the holy grail of fitness—but for me, it came with a significant price.

In this 193rd episode, I’m pulling back the curtain on my personal case study with Retatrutide, an experimental 'GLP-3' peptide currently making waves in the weight loss and biohacking communities.

I’ll break down exactly what this compound is, how it differs from traditional GLP-1 drugs like Ozempic, and why I, for one, found it to be a powerful but double-edged sword.

I will share the raw data I collected—the dramatic changes in my body composition and lab results—balanced against the reality of significant GI distress, muscle fatigue, and an unsettling, yet interesting psychological pull of a 'shortcut' to body perfection.

Whether you’re curious about the science behind the next generation of weight-loss peptides, or you’ve been considering experimenting with them yourself, you need to hear this experience. I’m sharing the good, the bad, and the uncomfortable so you can make an informed decision. Let’s dive in.

In this 192nd episode we take a closer look at a compound with a surprisingly long and fascinating history: methylene blue. Initially used as a textile dye in the 1800s, methylene blue has since found applications in medicine and surgery, and—more recently—conversations about mitochondrial function, energy production, and chronic illness.

My guest is Dr. Scott Sherr, an internal medicine physician, hyperbaric oxygen therapy specialist, Director of Education at HOMeHOPe, and Chief Medical and Health Education Officer at Troscriptions. Dr. Sherr brings a broad perspective to this topic, connecting the biochemistry of methylene blue with practical questions about chronic fatigue, fibromyalgia, autoimmunity, cancer-related fatigue, and mitochondrial support.

We’ll also discuss why Troscriptions uses a troche delivery system, how methylene blue may fit alongside hyperbaric oxygen therapy or red-light therapy, and—perhaps most importantly—where caution is needed. We’ll explore contraindications such as G6PD deficiency, potential medication and substance interactions, and questions surrounding methylene blue and psychedelic compounds, including classic psychedelics, ketamine, and MDMA.

And because wellness is never just about one molecule or one intervention, we’ll also talk about the nervous system. What does it mean to help someone move out of chronic sympathetic activation and toward a more parasympathetic, restorative state? And why might that shift be essential for healing, recovery, and resilience?

Let’s get into it with Dr. Scott Sherr.

If you would like to try out Troscriptions formulas, you can click this link!

https://hcp.troscriptions.com/join/71f20546-eff8-4ec2-9c6b-2757655e9618

Links & Websites:

Troscriptions.com

drscottsherr.com

homehope.org

onebasehealth.com

Instagram: https://www.instagram.com/troscriptions/

https://www.instagram.com/drscottsherr/

https://www.instagram.com/onebasehealth/

https://www.instagram.com/homehopeorg/

Youtube: https://www.youtube.com/@troscriptions

https://www.youtube.com/@drscottsherr

Linked In: https://www.linkedin.com/in/drsherr/

https://www.linkedin.com/company/troscriptions/

In this 191st episode, I explore a more subtle connection between anxiety and constipation...

Have you ever felt anxious without knowing why—only to realize that your digestion has been stalled for days?

Constipation isn’t always just about how often you have a bowel movement. It can also involve a breakdown in communication between the gut and the brain. When gut movement slows, bloating and pressure can build. And when the body’s sensory signals are muted, you may not feel the usual urge—or even much pain.

At the same time, the nervous system may still be receiving subtle signals that something is wrong. When those signals aren’t clearly interpreted, they may show up as generalized anxiety, restlessness, or unease.

In this episode, we’ll explore the connection between constipation, the vagus nerve, interoception, and anxiety—and consider how digestion and emotional well-being are deeply connected.

Because sometimes, the question isn’t only, “Why can’t I go?” It’s also: What is my body trying to tell me?

What if overcoming suffering isn’t about escaping pain, but learning how to meet it?

In this 190th episode, I explore ideas inspired by Buddhist teachings as interpreted by the Eastern philosopher Alan Watts, and consider whether our fear of suffering may sometimes become part of the suffering itself.

The Buddha taught that life includes dukkha—a kind of discomfort, dissatisfaction, and impermanence. We naturally seek pleasure and try to avoid pain, but perhaps peace comes not from choosing one over the other, but from learning to be present with both.

In this episode, we’ll explore what happens when we stop resisting discomfort and begin observing it directly. We’ll consider pain, childbirth, grief, illness, and even death—not as experiences to romanticize, but as natural parts of life that may hold the possibility of transformation.

Perhaps wellness isn’t the absence of suffering. Perhaps it’s the ability to remain present, grounded, and connected—even in the midst of it.

In this 189th episode, we explore intestinal permeability and the delicate gut barrier that helps separate the contents of the digestive tract from the rest of the body. We’ll discuss the role of tight-junction and barrier-associated proteins, including occludin, zonulin, and actomyosin, as well as the kinds of immune markers evaluated by tests such as Cyrex Labs Array 2.

We’ll also define autoimmunity: what happens when the immune system loses tolerance to the body’s own tissues. Using examples such as Hashimoto’s thyroiditis, multiple sclerosis, and lupus, we’ll consider whether antibodies against gut-barrier proteins necessarily indicate a direct autoimmune attack—or whether they may also reflect tissue damage, inflammation, and the immune system’s attempt to clean up injured tissue.

The conversation goes further, examining the close relationship between intestinal permeability and autoimmune disease. A compromised gut barrier may contribute to increased immune reactivity, while autoimmune conditions may themselves impair the gut’s ability to maintain a healthy barrier. Because proteins such as occludin and zonulin are also found in other barrier tissues—including the blood-brain barrier and lung barrier—this process may have implications for symptoms such as brain fog, environmental sensitivities, and systemic inflammation.

Finally, we’ll discuss ways to help interrupt this self-reinforcing cycle, including identifying dietary triggers, supporting gut-barrier integrity, improving immune regulation, and addressing the broader foundations of wellness.

Cyrex Labs: https://www.cyrexlabs.com/CyrexTestsArrays/tabid/136/Default.aspx

In this 188th episode, I offer a rebuttal to some recent headlines making a bit of a splash...

What if the headline telling you to “eat less protein to live longer” is getting far ahead of the actual science?

A recent article published by Cell Press, titled “The Hallmarks of Protein and Amino Acid Restriction in Aging and Longevity,” has generated significant media attention. Several major outlets interpreted the paper as evidence that reducing protein intake may improve healthspan and extend lifespan.

But there’s a problem: this was not a clinical trial. It was not a systematic review or meta-analysis. And it did not prove that humans should eat less protein.

In this episode, we’re going to unpack what the paper actually says—and what it does not say. We’ll look at the difference between a narrative review and stronger forms of clinical evidence, examine how findings from worms, flies, mice, and rats get translated into human nutrition headlines, and explore why protein restriction, amino acid restriction, and plant-versus-animal protein are not interchangeable concepts.

We’ll also talk about the special importance of protein for older adults, including its role in preserving muscle mass, strength, mobility, and independence. Because when protein intake goes down, something else has to replace those calories—and that makes the interpretation much more complicated than the headline suggests.

This isn’t an argument that protein restriction is necessarily wrong. It’s an argument for scientific humility. Interesting mechanisms involving mTOR, IGF-1, FGF21, and amino acid metabolism may generate important hypotheses—but a hypothesis is not the same thing as a clinical recommendation.

So today, we’re asking: Did the science really show that eating less protein helps humans live longer—or did the media turn a nuanced research review into a new dietary rule?

References:

The hallmarks of protein and amino acid restriction in aging and longevity

https://www.cell.com/cell-press-blue/fulltext/S3051-3839(26)00077-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS3051383926000770%3Fshowall%3Dtrue

Selling sickness: the pharmaceutical industry and diseasemongering

https://www.bmj.com/content/324/7342/886.1.abstract

I also want to thank Dr. Robert Malone for his expertise and commentary on this topic. If you would like to read a more thorough retort of this topic written by Dr. Malone, you can find his article here:

⁠www.malone.news/p/the-protein-panic-how-a-review-paper

In this 187th episode, I discuss what microplastics have to do with bile, gallstones, mitochondria, and cellular aging.

In this episode, we explore emerging research detecting microplastics in human bile—and the higher concentrations found in people with gallstones.

We’ll discuss how these particles may interact with biliary cells, contribute to mitochondrial stress, and promote a senescence-like “zombie cell” state.

We’ll also examine experimental findings on melatonin’s potential to protect mitochondrial function, while considering why healthy sleep may be more important than relying on supplementation.

From a functional medicine perspective, the conversation focuses on reducing avoidable plastic exposure, supporting liver and biliary function, maintaining healthy detoxification pathways, and building resilience through nutrition, movement, stress management, and restorative sleep.

Reference:

Zhan L, Fu L, Zeng Q, Liang R, Tang J, Liu J, Qian B, Xu Z,Che L. Microplastics accumulate in human bile and drive cholangiocytesenescence. Environ Sci Ecotechnol. 2026;31:100686.doi:10.1016/j.ese.2026.100686.

In this 177th episode, I sit down with Brian from the Chanda Center for Health to explore how integrative therapies — acupuncture, massage, chiropractic care, and physical therapy — are transforming care for people with long‑term physical disabilities, chronic pain, and spinal cord injuries. Brian shares his personal path from neuroscience to acupuncture and describes the Center’s origin, its founder Chanda Hinton’s advocacy to secure Medicaid coverage, and the real‑world impact of expanding services to address brain injury, MS, and other neurological conditions.

We discuss:

• How integrative care reduces hospitalizations and medication costs and why coverage matters for patients living on limited incomes
• The therapeutic benefits of acupuncture for spasm, nerve pain, sleep, and overall quality of life
• Practical clinic work: treating spasticity, bladder issues, peripheral and centralized neuropathic pain, and preventing serious complications
• Community‑building at the Chanda Center: accessible design, social programs, donor‑funded services, and adaptive recreation that help patients move from surviving to thriving
• Respectful ways to assist people with disabilities and the Center’s approach to dignity and independence
• Plans for program expansion, insurance integration, and how others can advocate for similar models
  

Whether you’re a clinician, caregiver, patient, or advocate, this conversation highlights how thoughtful, integrated care and community support can change lives and save systems money. Tune in for practical insights, policy wins, and inspiring stories from a care model built by and for people with physical disabilities.

Contact Information for The Chanda Center for Health:

• Email: info@chandacenter.org
• Website: https://chandacenter.org/ 
• LinkedIn: https://www.linkedin.com/company/chandacenter/ 
• Facebook: https://www.facebook.com/chandacenterforhealth/ 
• Instagram: https://www.instagram.com/chandacenterforhealth/ 
• YouTube: https://www.youtube.com/channel/UCkfFrHS_XY600aMVT6FYGBg 

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In this 176th episode, I sit down with Paul Austin to discuss the exciting, controversial, and promising topic of psychedelics.

Paul is the CEO and founder of The Third Wave, which is a company focused on providing information and resources on the safe use of psychedelic therapies. He also trains and coaches upcoming facilitators, and offers retreats around the world for people to come together for this very important work.

In this episode, we discuss many topics ranging from legality, microdosing vs. macrodosing, different types of psychedelic medicines, psychedelic research, and the subtle yet important difference in the description of these medicines as "psychedelics" vs. "entheogens."

Join us in this dynamic conversation as we enter into a literal renaissance in psychedelic therapies going forward. This is no longer fringe stuff here. It is real medicine, recognized by the FDA, that can offer an individual deep insights not readily available in normal everyday life. I even share some of my personal experiences with psychedelic journeys. They have been game-changers in my life. And I put them squarely in the "A Functional Approach" category of health and wellness interventions for my personal wellness journey.

You can find Paul at:

https://thethirdwave.co

https://www.paulaustin.co/

Instagram:@thirdwaveishere
@psychedeliccoachinginstitute
@microdosingcollective

LinkedIn:

https://www.linkedin.com/in/paul-f-austin/

In this 175th episode, I get a bit vulnerable and share some personal experiences of loss. Why? Because we all experience similar loss. And we are all in this together. And sharing our experience with each other has the potential to heal. Communication, connection, and reflection are all so important for our health and wellbeing. It is truly a Functional Approach...

In this 174th episode, I revisit the topic of mold but in much more detail. Today I sit down with a true expert in the field, Jason Earl, who is the founder and CEO of the at-home mold testing company, Got Mold?

Our conversation covers a broad spectrum of topics from differences in mold testing, medical conditions typical of chronic mold exposure, the difference between mold spores, mycotoxins, and volatile organic compounds (VOCs).

Jason is a master as challenging myths around mold and offering a sober reality of mold exposures and testing.

Jason's expertice on the topic is immediately apparent, and I trust this man completely to tell it like it is.

You can find him by clicking the following link:https://gotmold.docsend.com/view/a5wvz2dh9cakehyu

Or at:

www.gotmold.com

questions@gotmold.com

Facebook: /gotmold

LinkedIn: in/jearl

And if you would like to get your home or office tested, you can click this link for a 10% off discount!

https://www.gotmold.com/afunctionalapproach/

In this 137 episode, I showcase the peptide Epitalon. This amazing peptide has been shown to improve wellness and longevity by promoiting better sleep, improving immune function, improving endocrine function, improving immune function, and lowering cardiovascular and neurovascular risk.

And... It works even better when combined with Thymulin-Zinc, which I discussed in my last episode!

But don't just take my word for it! Here are some literature citations that are worth a read:

References:

1. Al-Dulaimi S, Thomas R, Matta S, Roberts T. Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity. Biogerontology. 2025;26:178. doi:10.1007/s10522-025-10315-x.
2. Anisimov VN, Arutjunyan AV, Khavinson VK. Effects of epithalamin on free-radical processes in humans and animals. Neuro Endocrinol Lett. 2001;22(1):9–18.
3. Anisimov VN, Khavinson VK, Alimova IN, Semchenko AV, Yashin AI. Epithalon decelerates aging and suppresses breast adenocarcinoma development in transgenic HER-2/neu mice. Bull Exp Biol Med. 2002;134(2):187–190. doi:10.1023/A:1021104819170. PMID:12459848.
4. Anisimov VN, Khavinson VK, Mikhailova EG, Yashin AI. Effect of epitalon on the incidence and age of spontaneous mammary carcinomas in female C3H mice. Bull Exp Biol Med. 2002;133(4):391–395. doi:10.1023/A:1017676104877.
5. Anisimov VN, Khavinson VK, Popovich IG, Zabezhinski MA, Alimova IN, Rosenfeld SV, et al. Effect of epitalon on biomarkers of aging, lifespan, and spontaneous tumor incidence in female SHR mice. Biogerontology. 2003;4(4):193–202. doi:10.1023/A:1025114230714. PMID:14501183.
6. Anisimov VN, Khavinson VK, Provinciali M, Alimova IN, Baturin DA, Popovich IG, et al. Inhibitory effect of epitalon on spontaneous mammary tumors in HER-2/neu transgenic mice. Int J Cancer. 2002;101(1):7–10. doi:10.1002/ijc.10570. PMID:12209581.
7. Araj SK, Brzezik J, Mądra-Gackowska K, Szeleszczuk Ł. Overview of epitalon—highly bioactive pineal tetrapeptide with promising properties. Int J Mol Sci. 2025;26(6):2691. doi:10.3390/ijms26062691.
8. Gatta M, Dovizio M, Milillo C, Ruggieri AG, Sallese M, Antonucci I, Trofimov A, Khavinson V, Trofimova S, Bruno A, Ballerini P. The antioxidant tetrapeptide Epitalon enhances delayed wound healing in an in vitro model of diabetic retinopathy. Stem Cell Rev Rep. 2025;21(6):1822–1834. doi:10.1007/s12015-025-10911-x.
9. Goncharova ND, Vengerina AA, Shmalii AV, Khavinson VK. Peptide correction of age-related pineal dysfunction in monkeys. Adv Gerontol. 2003;12:121–127. [Russian]
10. Goncharova ND, Vengerina AA, Khavinson VK, Lapin BA. Peptide correction of pancreatic hormonal dysfunction in aging monkeys. Bull Exp Biol Med. 2004;138(1):80–83. doi:10.1023/B:BEBM.0000046946.25425.f5.

In this 172nd episode I continue with my mini-series on peptide therapy with a focus on Thymulin-Zinc.

We will cover what the thymus gland is/does, how it changes with age, the mechanisms by which Thymulin‑Zinc supports immune‑endocrine communication and neuroimmune health, practical clinical uses and dosing, and safety considerations for integrating this peptide into longevity‑focused care.

If you’re curious about restoring immune coordination rather than just boosting immunity, or if you struggle with ongoing immune challenges including things like Post-COVID syndrome, chronic Epstein-Barr infection, etc., this episode is for you.

References: 

1. Bach JF, Dardenne M. Thymulin, a zinc-dependent hormone. Med Oncol Tumor Pharmacother. 1989;6:25–29. doi:10.1007/BF02985220.
2. Chandratilleke D, Marsh JA. The effect of thymulin on avian IL-2 receptor expression. Int J Immunopharmacol. 2000;22(11):887–896. doi:10.1016/S0192-0561(00)00051-5.
3. Chrousos GP, Kino T. Glucocorticoid signaling in the cell: expanding clinical implications to complex human behavioral and somatic disorders. Am J Physiol Endocrinol Metab. 2007;292(1):E9–E18. doi:10.1152/ajpendo.00085.2007.
4. Goya RG, Scapagnini G, Veldhuis JD. Growth hormone-releasing activity of thymulin on rat pituitary cells in vitro. Neuroendocrinology. 1999;69(1):20–27. doi:10.1159/000054395.
5. Goya RG, Scapagnini G, Veldhuis JD. Effects of growth hormone and thyroxine on thymulin secretion in aged rats. J Gerontol A Biol Sci Med Sci. 2000;55(4):B170–B176. doi:10.1093/gerona/55.4.B170.
6. Haddad JJ. Thymulin and zinc-mediated inhibition of endotoxin-induced proinflammatory cytokines and NF-κB activation. Mol Immunol. 2009;47(2–3):205–214. doi:10.1016/j.molimm.2009.09.034.
7. Khavinson VK, Kuznik BI, Linkova NS. Peptide regulation of immune system aging. Russ J Immunol. 2019;13(1):23–32. Available from: https://rusimmun.ru/jour/article/view/1209/en_US
8. Khavinson VK, Malinin VV, Loginov VI, Nikitina AA. Effect of pineal peptide preparations on thymus-dependent immune reactions. Bull Exp Biol Med. 1989;108(2):204–206. doi:10.1007/BF00839241.
9. Khavinson VK, Morozov VG. Peptides of the pineal gland and thymus: their role in aging and age-associated diseases. Expert Opin Biol Ther. 2009;9(12):1549–1560. doi:10.1517/14728220903512991.
10. Lunin SM, Khrenov MO, Glushkova OV, et al. Extrathymic production of thymulin induced by oxidative stress and cell death. Int J Immunopathol Pharmacol. 2017;30(1):58–69. doi:10.1177/0394632017694625.

In this 171st episode, I discuss a messy, though fascinating paradox: Infections can trigger autoimmune disease, they can worsen existing autoimmunity, and—surprisingly—some infections can actually protect against it.

We’ll unpack the science, from molecular culprits and autoantibodies to the surprising role of helminths (parasitic worms) and peptides like tuftsin, and explore how clinicians decide when to treat an infection and when to let biology do its balancing act.

Citations:

Infections and autoimmunity--friends or foes?

https://pubmed.ncbi.nlm.nih.gov/19643667/

Infections: a double-edged sword in autoimmunity

https://pubmed.ncbi.nlm.nih.gov/29847440/

Parasitic worms and inflammatory diseases

https://pubmed.ncbi.nlm.nih.gov/16965287/

Helminth-Related Tuftsin-Phosphorylcholine Compound andits Interplay with Autoimmune Diseases

https://pubmed.ncbi.nlm.nih.gov/30905098/

In this 170th episode, I continue with my mini-series on Peptide Therapy with a product called Lipotone which contains the peptide DNF-10.

This particular peptide can be a nice safe alternative to the Ozempic class of medications for things like weight loss. But it can also be a helpful player in reducing inflammation, improving blood sugar and insulin signaling, and more.

I will admit that I have avoided working directly with weight loss cases in my practice, and like to think of supporting weight loss as more of a positive side-effect of an otherwise successful wellness effort. But there are some real reasons to lose that extra weight, if it is something you are carrying around.

if you are struggling with those evening munchies, needing some assistance while on a dietary modification program, or just want to shed a few poinds, this episode may be for you!

In this 169th episode, I speak with Chase Zittrauer, my rep for Cyrex Labs.

We spent some time diving into one of the fastest-growing health crises of our time — Alzheimer’s and related dementias — and what cutting‑edge testing can reveal long before symptoms show up.

We unpack the rising global and U.S. burden ofAlzheimer’s: the financial, emotional, and caregiving toll it takes on families. Then we’ll explore a provocative link many clinicians are watching — how COVID-19, long COVID, and immune dysregulation might influence brain health.

We discuss a unique laboratory testing approach from Cyrex Labs - The Alzheimer's LINX panel - that looks for early immune signals of brain stress — antibodies to key brain proteins like amyloid beta and tau, as well as cross‑reactivity with pathogens, chemicals, and foods.

We’ll explain why plaques and tangles aren’t the wholestory, why single‑target drugs fall short, and how lifestyle andmetabolic factors — think insulin and blood sugar — matter in prevention.

Chase shares his own test results and what they revealed about pathogens, phthalates, and food triggers. We also cover the blood‑brain barrier, aluminum and other chemical neoantigens, oral pathogens, traumatic and emotional brain injury, and practical testing strategies, including Cyrex Array‑2, a fantastic leaky‑gut panel.

If you have a family history of dementia, genetic risks, past head injuries, or just want earlier clarity about brain health, this episode is for you. Stick around — we’ll break down what the tests can tell you and what to do next.

Check out Cyrex Labs Test Arrays Here!

https://www.cyrexlabs.com/CyrexTestsArrays/tabid/136/Default.aspx

And I am always available for an initial consultation. If you are feeling called... You can reach me here:

https://afunctionalapproach.net/schedule-an-appointment

In this 168th episode, I discuss connection...

I’ve always been a people person. I’m the one who smiles at a stranger in a lobby, who says hello without expecting anything back. Most mornings that greeting bounces off the world and keeps going — sometimes met with a smile, sometimes met with silence. I don’t take it personally; I don’t always know the story behind someone’s eyes. But I do feel compelled to notice people anyway. For me, that little act of connection is a spiritual practice. It’s how I show up in the world.

We’re built for each other. Long before cities and screens, humans lived in tight bands of twenty to a hundred-fifty — communities that met, traded, raised children, and made life together. Science backs up what our hearts already know: people with strong social ties live longer, recover better, think more clearly, and suffer less from anxiety, depression, and isolation. Yet today, surrounded by millions, many of us feel lonelier than ever — scrolling instead of speaking, commenting instead of sharing a meal, passing by without eye contact.

This episode is a gentle invitation. I’ll share a personal morning encounter, a recent gathering in Northern California that reminded me what true presence feels like, and simple, practical ways to rebuild community: volunteering, joining a hiking group, tending a community garden, or learning a new game with neighbors. These aren’t big, dramatic fixes — just small, mindful choices to lean toward people again.

If you’re craving connection or wondering how to start, stay with me. This conversation is less about data and more about heart — about the magic that happens when we choose, intentionally, to be present for one another. Connection is waiting. Let’s take a step toward it together.

In this 167th episode, I’m joined by Dr. Jordan Barber, Doctor of Acupuncture and Oriental Medicine with over 20 years in clinical practice.

He is the co-author of "Thinking in Chinese Medicine: A Patient's Guide to Acupuncture" (2026) and "Realigning Medicine: Building an Authentic, Fulfilling, and Thriving Healthcare Practice" (2025).

Our focus today is on an important but often sidelined issue:erectile dysfunction. I hear about ED frequently from patients, usually as an aside to another medical concern — why is that?

We’ll define ED and its varying levels, separate myths from facts, and explore distinctions between performance anxiety, behavioral causes like problematic pornography use, and physical drivers. We’ll discuss whether ED always comes down to circulation, how Chinese Medicine frames theproblem (circulation, hormones, mood, metabolic disease, etc.), and what conventional medicine offers — including how PDE5 inhibitors (Viagra/Cialis) work by upregulating eNOS to improve blood flow, and where concerns about iNOSfit in.

We’ll also cover practical strategies: diet, lifestyle, TCMapproaches, and when a condition may be advanced enough that different interventions are needed. Dr. Barber will share insights from his books — including the idea that symptoms are expressions of the body’s adaptation within a network of relationships — and preview findings from his dry needling vs. TCM acupuncture research.

Stick around: the dry needling conversation deserves its own deep dive, and we’ll tee that up for a future episode.

Contact info:

Website:  https://drbarberclinic.com/

Instagram: https://www.instagram.com/jbarberlac/

Thinking in Chinese Medicine Book:  https://www.thinkinginchinesemedicine.com/

Amazon link: https://www.amazon.com/Thinking-Chinese-Medicine-Patients-Acupuncture/dp/B0GWMLPZ5Q/ref=sr_1_1?crid=39H4CP17T3JLP&dib=eyJ2IjoiMSJ9.d0GaAFsPYlI-LqtZui6tnxzqwUF_QcVWpR5FcFbhJlpJ9msMfLdYXcM_AA2iCCH7xW7gcMMUhomoh3zwRLhQeWffiXkVbxfBJ4UN4kl0uJKOU3RM2IhKe1t7TwM2GEH7UD2JNt7R_8UtXy_02Q-4dckIEGBXwb8lGA0KLBaq_yHKl1J2uVuamuvrkW2OtgwZNO4W6WDM4TQj5hc7_oc_ZZ8ro6s2Rl_gaUdIEfFJ6Zo.uW67WYn2TjIw_fYu-NKytQVfntqhP0YTj-nyD876jjU&dib_tag=se&keywords=thinking+in+chinese+medicine&qid=1779389056&sprefix=Thinking+in+Chinese+%2Caps%2C151&sr=8-1

In this 166th episode, I continue with my mini-series on peptide therapies and discuss Copper GHK.

Copper GHK is a small copper-bound tripeptide that affects repair, aging, and gene expression. I cover its natural role in plasma and tissues, how levels fall with age, and the surprising breadth of its actions—from extracellular matrix remodeling and antioxidant effects to cognitive protection, cardiovascular benefits, and boosted wound healing.

I also walk through the molecular mechanisms, real-world applications, and practical considerations for clinicians and listeners interested in regenerative support.

Citations:

1.     Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int.2015;2015:648108. doi: 10.1155/2015/648108. Epub 2015 Jul 7. PMID: 26236730;PMCID: PMC4508379. 

2.     Pickart L, Margolina A. The Effect of the Human Plasma Molecule GHK-Cu on Stem Cell Actions and Expression of Relevant Genes. OBM Geriatrics 2018;2(3):009;doi:10.21926/obm.geriatr.1803009. 

3.     Adnan SB, Maarof M, Fauzi MB, Fadilah NIM. Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review. Int J Med Sci. 2025 Oct1;22(16):4175-4200. doi: 10.7150/ijms.118118. PMID: 41209547; PMCID:PMC12595317. 

4.     Zoughaib M, Luong D, Garifullin R, Gatina DZ, Fedosimova SV, Abdullin TI. Enhanced angiogenic effects of RGD, GHK peptides and copper (II) compositions in synthetic cryogel ECM model. Mater Sci Eng C Mater Biol Appl. 2021Jan;120:111660. doi: 10.1016/j.msec.2020.111660. Epub 2020 Oct 21. PMID:33545827. 

5.     Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987. doi:10.3390/ijms19071987. PMID: 29986520; PMCID: PMC6073405. 

In this 165th episode, I chat with Amy Behimer, Doctor of Pharmacy & Health Coach, about her approach to chronic conditions.

As a person with Multiple Sclerosis and a few other autoimmune conditions, Dr. Amy knows firsthand what can work to manage autoimmunity.

During this conversation, Amy and I discuss her philosophy of managing chronic conditions, Multiple Sclerosis and autoimmunity in general, diet/lifestyle approaches, and so much more!

I really enjoyed this conversation. Dr. Amy is such a bright light and an asset to those working through some very difficult medical conditions.

You can find her website at: https://amybehimercoaching.com/ www.amybehimercoaching.com/join

Instagram:@amybehimercoachingOr her podcast: Autoimmune Health Secrets

And if you would like to take her free quiz to help identify a habit you want to make or break, you can do so here: www.amybehimercoaching.com/quiz

In this 164th episode, we trace the Beljanski Foundation’s origin and mission, explore its signature research tools (including the Oncotest), and dive into the botanicals and molecular components used in the Foundation’s anticancer approaches.

The conversation covers how select plant alkaloids found in herbs like Pao Pereira, Rauwolfia Vomitoria, Ginkgo Biloba, Green Tea, and specific fragments of RNA act on cancer cells while sparing healthy tissue, how these agents interact with chemo/radiation (efficacy and toxicity), and details about the Foundation’s upcoming San Diego conference.

If you or someone you know is going through cancer, this episode is not one to miss!

Links:

Integrative Cancer Conference (San Diego, CA 6/26/26-6/29-26):https://integrativecancerconference.com 

Website:

https://www.maisonbeljanski.com/ 

Social:
instagram.com/BeljanskiFoundation

facebook.com/TheBeljanskiFoundation

youtube.com/@BeljanskiFoundation

linkedin.com/company/The-Beljanski-Foundation

twitter.com/BeljanskiF

tiktok.com/@TheBeljanskiCancerTalk

In this 163rd episode, I simply recognize the fear and struggle we are all feeling in this time of war, financial stress, and uncertainty.

Just a small public service announcement and a call to action to remember to let in the positive, lovely things. This is how we will get through. Remember, you are not alone, and we will get through this together!

Connection is the meaning of life.

Much love to you all...

Dr. Jim

In this 162nd episode I begin to unpack the topic of peptides—what they are, how they work, and why tiny chains of amino acids are becoming major players in healing and recovery.

In this particular episode I focus on BPC-157: a 15–amino‑acid fragment derived from human gastric juice that’s been studied since the 1990s for wound healing, tendon and ligament repair, gut protection, anti‑inflammatory effects, angiomodulation, and potential neuroprotection.

I will walk through real‑world considerations: common administration routes (oral, subcutaneous, intramuscular, IV, topical), pros and cons of liposomal oral delivery, typical dosing examples (e.g., liposomal BPC-157 at 500 mcg twice daily), cycling strategies for long‑term use, time to effect, and typical cost ranges for peptide therapy.

We also cover safety caveats—especially the theoretical cancer concern that warrants avoiding use with known malignancy.

Finally, we compare related formulas (BPC blends with KPV or TB‑500) and practical tips for anyone curious about peptide therapy.

Episode takeaways

• What peptides are and why they act as cellular messengers.
• How BPC‑157 may speed healing and protect organs and the gut.
• Practical dosing, delivery options, cost realities, and safety considerations.
• How to evaluate formulations and when to seek medical oversight.

Citations:

A new gastric juice peptide, BPC. An overview of thestomach-stress-organoprotection hypothesis and beneficial effects of BPC

https://pubmed.ncbi.nlm.nih.gov/8298609/

In this 161st episode I unpack vascular dementia — what causes it, how it differs from (and often overlaps with) Alzheimer’s, and the brain and vascular mechanisms that drive cognitive decline. I review some common clinical features of vascular dementia, noteworthy MRI findings, and the major vascular and metabolic risk factors involved in the development and progression of this disease.

This is a great example of how a preventative approach nowcan save a lot of trouble later!

Citations:

Homocysteine and vascular disease

https://pubmed.ncbi.nlm.nih.gov/8597939/

Trimethylamine N-Oxide: The Good, the Bad andthe Unknown

https://pmc.ncbi.nlm.nih.gov/articles/PMC5127123/

In this 160th episode, I riff a bit on a book my former Ju-Jitsu Sensei wrote and gifted to me many years back. The concept here is "vision."

There is a difference between dreams and vision. And it takes vision to make change happen.

I share a story about an elephant from my book, and discuss how the very same principles can be found in our lives.

This episode is one of encouragement. Encouragement to make your dreams your reality.

In this 159th episode, I take a clear, evidence-focused look atBreast Implant Illness — what implants are made of, how our bodies can react to them, and why some people develop unexplained systemic symptoms. I walk you through the history—major recalls, FDA actions, and key studies—so you can see how awareness has changed and why recommendations are evolving.

I break down the common symptoms I hear about most (fatigue, brain fog, pain, neurological issues), related conditions (autoimmune disease, chronic fatigue, implant-associated cancers), and the biology behind it: siloxane (silicone) leaching, how bacterial biofilms or mold can play a role,  and how the fibrous capsule surrounding implants can trap toxins and sometimes become the site of serious cancers.

Then I get practical: how to evaluate symptoms, questions toask an explant surgeon, what diagnostics and pathology can reveal, and an evidence-informed approach to recovery—detox pathways, mitochondrial support, addressing infections or mold, and lifestyle steps that help. I emphasize individualized, multidisciplinary care and give actionable next steps for anyone worried about their implants.

This episode is for people with implants who are experiencing unexplained symptoms, friends and family supporting someone with suspected breast implant-related concerns, and anyone considering implants who wants balanced, practical information.

Explant specialist in San Diego, CA:

Mouchammed Agko, M.D.

https://www.cityofhope.org/patients/find-a-doctor/mouchammed-agko

In this 158th episode, I follow up on my last episode about my journey into and out of Hell Hole Canyon in the Southern California Anza Borrego desert.

You already heard about my journey itself, but I felt it only fitting to explain just what happened to me physiologically. For example.... How can a person get so dehydrated with a stomach full of water?!? And just how might something like a history of gluten sensitivity and some head trauma contribute to the situation?

It took me a while to figure that one out for myself. In fact, it took a year of Functional neurology training for me to fully grasp the mechanisms involved.

Join me for a deeper dive into this rather peculiar chain of events. These things don't just happen to me... The mechanisms described in this episode are literally EVERYWHERE! For me, it was a backpacking trip. For you, it may be a nice day sailing out on the bay, or a day at an amusement park that sets the stage for something unexpected.

In this 157th episode, I recount a harrowing experience of survival, persistence, calm rational thinking, and realistic goal setting - all in the face of very real danger.

My trip into and out of Hell Hole Canyon in Anza Borrego State Park, a literal desert paradise here in Southern California, started out as a lovely solo backpack and quickly turned into something much more important. It was a test of will, a humbling, and an expression of true freedom.

Listen in and consider how goals, no matter how big, can be looked at and worked through mindfully. And in so doing... An approach like this can offer success, where failure often lurks around every corner.

https://en.wikipedia.org/wiki/Anza-Borrego_Desert_State_Park

In this 156th episode, I share a recent gluten exposure experience. This exposure was one of the largest (accidental) exposures to gluten that I can remember... One whole cracker.

Listen in and hear about how something like that can happen to us in the GF community, how I responded to knowing I just poisoned myself, and just how powerful our minds and spirits can be when something like this happens.

I did not get off scott-free, but spoiler... No migraine!!

In this 155th episode, we reflect on loss—big and small—and how it shapes our lives. From everyday comforts and relationships to health, habits, and grief, we explorehow attachment can both comfort and weigh us down. Rather than denying painful emotions, the conversation invites you to feel them fully, practice presence, and find the freedom in impermanence. We cover how acceptance, gratitude for the present moment, self‑compassion, and connection with others can help us move through loss and open space for new possibilities.

In this 154th episode, I unpack hypochlorhydria — low stomach acid — exploring what it is, why stomach acid matters for digestion and immune defense, and how reduced acid can cause symptoms that often mimic reflux.

We review common causes (long‑term PPI use, H. pylori, autoimmune gastritis, age, etc.), practical evaluation (when to test, which labs to order), and some dangers of living with a low stomach acid condition.

This is a very common condition that likely impacts you or someone you know. Yet it is managed incorrectly, most of the time.

In this 153rd episode, I speak with Morgan Smith, CEO of Kalm with Kava, founder of Pu'iwa Hawaiian Farms, and Board member of the International Kava Organization.

We discuss concepts about how kava came into his life, and how this herb helped him manage the ever-increasing stresses of work and family.

We discuss how this herb, kava, works in the body, where and how it is grown, some cautions of its use, and some traditional ceremonial practices used by indigenous people of the Pacific Islands.

If you have never heard of kava before, I encourage you to listen in on this one. Morgan is a wealth of information, and we had a wonderful discussion.

My apologies for the audio static in the very beginning of the episode. We got it sorted out quickly, so hang in there!

You can find Morgan and his products through his website and social media links here:

www.kalmwithkava.com

Facebook:  https://www.facebook.com/KalmwithKava

Instagram:  https://www.instagram.com/explore/search/keyword/?q=Calm%20with%20kava

Reddit:  https://www.reddit.com/r/kalmwithkava/

YouTube: https://www.youtube.com/@Drinkkalm

In this 152nd episode, I speak with Prashanthi Amarnath about how Taoist principles can help reshape our relationship to uncertainty, fear, decision‑making, and our emotional life.

We discuss how uncertainty affects physiology and the nervous system. The conversation explores why the mind resists paradox and how cultivating perceptual flexibility — the “non‑fixed mind” Lao Tzu describes — expands relational attunement and emotional plasticity.

We discuss the concept of "wu wei" as an inner posture of effortless responsiveness rather than passivity, and discuss how embracing paradox can free decision‑making.

We discuss these things and much more! Tune in for a lovely conversation.

You can find Prashanthi's book Embracing Paradox through Amazon here:

https://a.co/d/cibPyFn

In this 151st episode, we unpack Brain-Derived Neurotrophic Factor (BDNF) — often called “fertilizer for the brain.” We explore what BDNF is, why it matters for learning, memory, and mood, and how low BDNF shows up in conditions like depression, cognitive decline, and neurodegenerative disease.

Then we dive into evidence-based strategies to naturally support BDNF through exercise, nutrition, sleep, stress management, and targeted supplements, plus emerging data on acupuncture.

Citations:

Electroacupuncture at the Baihui acupoint alleviates cognitive impairment and exerts neuroprotective effects by modulating the expression and processing of brain-derived neurotrophic factor in APP/PS1 transgenic mice

https://pubmed.ncbi.nlm.nih.gov/26739187/

The neuroprotective role of acupuncture and activation of the BDNF signaling pathway

https://pubmed.ncbi.nlm.nih.gov/24566146/

Potential Moderators of Physical Activity on Brain Health

https://pmc.ncbi.nlm.nih.gov/articles/PMC3523571/

Neuroplasticity - exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects

https://pubmed.ncbi.nlm.nih.gov/20726622/

Brain foods: the effects of nutrients on brain function

https://pmc.ncbi.nlm.nih.gov/articles/PMC2805706/

License to run: exercise impacts functional plasticity in the intact and injured central nervous system by using neurotrophins

https://pubmed.ncbi.nlm.nih.gov/16263961/

Effects of curcumin on brain-derived neurotrophic factor levels and oxidative damage in obesity and diabetes

https://pubmed.ncbi.nlm.nih.gov/24476477/

In this 150th episode, I take a moment to riff on the importance of letting go of control.

Of course, a life without some form of control is chaotic and might lend itself to being controlled by other people or institutions. I am not talking about letting go of complete control. Rather, I am suggesting here that our fixation on being in control could be holding us back or even doing us harm.

Take the next 12 or so minutes to listen to this episode and feel into how you might be fixating on control in your own life. And how might fear play into this fixation?

When you give this some consideration, you might just find some interesting details about your outlook on life that could be improved. And that is a Functional Approach...

In this 149th episode, I do a deep-dive into autoimmunity, laboratory testing, food sensitivity, chemical sensitivity, and all things immunology.

On this day I had the significant honor of sitting down with a giant in the integrative and functional medicine arena, Dr. Aristo Vojdani.

I have followed Dr. Vojdani's work since my earliest days of practice back in 2002. The diagnostic approach that he brings to the table through Cyrex Labs was one of the defining concepts in my personal evolution as a clinician. I saw and continue to see a depth of thought and understanding about how the immune system operates that I simply didn't (and still don't) see from other laboratory testing.

Dr. Vojdani holds Ph.D.'s in Microbiology & Immunology, is the founder of Immunosciences Laboratories and co-founder of Cyrex Laboratories, has published over 200 articles in highly respected medical journals, holds 17 patents, and has published multiple books. Long story short, Dr. Vojdani is a scientist of merit and one that we are fortunate to have looking out for our health and wellness!

You can look further into the work that Dr. Vojdani has offered at the following websites:

www.JoinCyrex.com

https://immunoscienceslab.com/

And you can always reach Chase Zittrauer - My Cyrex Labs Rep (who I have had as a guest on my podcast, and who is a wonderful human) at:

Chase.Zittrauer@cyrexlabs.com

In this 148th episode we delve into the intricacies of cardiovascular health by shining a light on some often-overlooked cardiovascular risks that could be influencing your heart health: trimethylamine N-oxide (TMAO), oxidized low-density lipoprotein (oxLDL), and homocysteine.

These biochemical markers provide crucial insights into our cardiovascular health, yet many people remain unaware of their significance or even their existence.

Join us as we explore how these compounds are formed, their implications for heart disease, and how you can take control of your cardiovascular well-being.

Citations:

Mechanistic Insights into the Oxidized Low-Density Lipoprotein-Induced Atherosclerosis

https://pubmed.ncbi.nlm.nih.gov/33014272/

Gut Microbiota in Hypertension and Atherosclerosis: A Review

https://pubmed.ncbi.nlm.nih.gov/33003455/

Homocysteine Metabolites, Endothelial Dysfunction, and Cardiovascular Disease

https://pubmed.ncbi.nlm.nih.gov/39859460/

In this 147th episode, I discuss the recent California law taking effect on Janurary 1, 2026 enforcing the supplementation of Folic Acid into corn masa (corn flour). This will impact corn tortillas, tamales, corn chips, etc.

It just so happens that upwards of 40% of the people this new law is intended to protect have a genetic trait where they cannot process folic acid properly.

In this episode we will discuss the reasons why California has made this new law, who it is meant to protect, why it is a terrible idea, and how it is a hidden (though likely an unintended) attack against a specific ethnic group.

Citations:

Folic acid and vitamin B12 fortification of food for preventing neural tube defects in Europe

https://www.bmj.com/content/361/bmj.k1572/rr-

0#:~:text=Folic%20acid%20is%20a%20synthetic,unable%20to%20process%20folic%2

0acid.

Circulating folic acid in plasma: relation to folic acid fortification

https://pmc.ncbi.nlm.nih.gov/articles/PMC3763811/

Methylenetetrahydrofolate Reductase Deficiency

https://www.ncbi.nlm.nih.gov/books/NBK66131/

NIH website: Folate

https://ods.od.nih.gov/factsheets/Folate-

HealthProfessional/#:~:text=People%20with%20an%20MTHFR%20polymorphism,defe

cts%20below)%20%5B41%5D.

Selenium protects against the likelihood of fetal neural tube defects partly via the

arginine metabolic pathway

https://pubmed.ncbi.nlm.nih.gov/35263693/

In this 146th (bonus) episode, I riff a bit on the concept of ritual as we turn the page of a new year. The focus and motivation of the episode though is one of gratitude and connection. This podcast has covered a lot of topics, but if there is one concept that I hope comes through strongly it is that we are all in this thing together. My hope is that there is something discussed here on this platform that touches your soul in some way. The fact that so many of you have followed along is so touching to me. I have so much gratitude for you all. Thank you so much for your time and attention. I wish you all a very exciting New Year!

In this 145th episode I discuss concepts around "Transitional Flow." This is a concept I became keenly aware of through my training of Ju-Jitsu, so many years ago. Understanding the principles of transitional flow I can see it everywhere. It is certainly useful on the sidewalks, in the market, during conversations or arguments... It is a skill that lends itself to an easier life experience.

Keeping with this concept I discuss various lessons and stories from Zen teachers like Alan Watts such as the story of a Zen Master and a Geisha girl.

However, the larger point of this episode focuses upon how to live a life in such a way that death becomes something of ease and grace. Are you living a life of struggle? Or are you flowing through life as if in a dance with the cosmos? And how will you face those final moments? With struggle, or with a life of practiced flow?

In this 144th episode I discuss various aspects of pain and suffering. The inspiration for this topic came to me recently as I was laying in bed, suffering from a nasty gluten-induced migraine, feeling sorry for myself, and pondering concepts around how I was processing the pain I was experiencing.

I discuss some Traditional Chinese Medical concepts around pain and stagnation, some neurological concepts about how pain is perceived and processed by the brain and nervous system, and riff a little on the philosophy of pain and suffering.

By the end of my time there in bed for the second time in a one month period, I came to some conculsions which will help me through my experiences with pain for the rest of my like. There was a phase shift of sorts - A new way of thinking. I would like to share that with you here.

And as promised... Here is a link to a previous podcast episode on pain and migraine:

"LSD for migraines? Well... Yes, kinda!"

https://open.spotify.com/episode/45AjS5DjMkKkBiidHhXjtG?si=zwjGeW-cQc2Sgz4kvMgMlQ

In this 143rd episode I unpack some thoughts about fear. I was inspired about this topic from a recent conversation I heard on the Duncan Trussell Family Hour Podcast between Duncan and Ram Dev. There were many topic discussed but fear came up and it just struck a chord.

And so I sat down and wrote out some thoughts...

If you are interested to hear the conversation you can check it out here:

Duncan Trussell Family Hour #724 - Ram Dev

https://open.spotify.com/episode/5vYIE7nU2zCW6Y8LucFtrx?si=2jnDC_UHTl2vIWVUyykxoQ

In this 142nd episode, we delve into the often-overlooked process of how industrial seed oils are made and why their widespread use may be harmful to our health. From the collection of seeds to the final product, the manufacturing process involves several steps, including high-temperature heating and the use of harmful solvents that raise serious health concerns.

We'll uncover the six critical reasons you should be cautious about consuming these oils, touching on issues like their impact on our omega-6 to omega-3 ratios and the potential risks linked to genetically modified ingredients.

Additionally, we'll introduce healthier alternatives for cooking oils that can support your well-being without the negative effects associated with industrial seed oils. Join us for an enlightening discussion that could change how you think about the oils you use daily.

Don't miss this chance to learn about making better dietary choices for a healthier lifestyle!

Literature Citations:

Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century

https://pubmed.ncbi.nlm.nih.gov/21367944/

Heated vegetable oils and cardiovascular disease riskfactors

https://pubmed.ncbi.nlm.nih.gov/24632108/

Evaluation of the deleterious health effects of consumptionof repeatedly heated vegetable oil

https://pmc.ncbi.nlm.nih.gov/articles/PMC5616019/

n-3 Polyunsaturated Fatty Acids and Cardiovascular Disease:Principles, Practices, Pitfalls, and Promises – A Contemporary Review

https://pmc.ncbi.nlm.nih.gov/articles/PMC5848472/

Dietary lipids and risk of autoimmune disease

https://pubmed.ncbi.nlm.nih.gov/8050192/

Omega-6 to omega-3 polyunsaturated fatty acid ratio andsubsequent mood disorders in young people with at-risk mental states: a 7-yearlongitudinal study

https://www.nature.com/articles/tp2017190

Trans Fat Consumption and Aggression

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032175

Dietary linoleic acid elevates endogenous 2-AG andanandamide and induces obesity

https://pubmed.ncbi.nlm.nih.gov/22334255/

Soybean Oil Is More Obesogenic and Diabetogenic than CoconutOil and Fructose in Mouse: Potential Role for the Liver

https://pubmed.ncbi.nlm.nih.gov/26200659/

Omega-6 vegetable oils as a driver of coronary heartdisease: the oxidized linoleic acid hypothesis

https://openheart.bmj.com/content/5/2/e000898

A host-microbiome interaction mediates the opposing effectsof omega-6 and omega-3 fatty acids on metabolic endotoxemia

https://pubmed.ncbi.nlm.nih.gov/26062993/

Marked elevations in pro-inflammatory polyunsaturated fattyacid metabolites in females with irritable bowel syndrome

https://pmc.ncbi.nlm.nih.gov/articles/PMC2853445/

Home use of vegetable oils, markers of systemicinflammation, and endothelial dysfunction among women

https://pubmed.ncbi.nlm.nih.gov/18842776/

Relationship of omega-3 and omega-6 fatty acids with semencharacteristics, and anti-oxidant status of seminal plasma: A comparisonbetween fertile and infertile men

https://www.sciencedirect.com/science/article/abs/pii/S0261561409001587

Dietary fat and risk for advanced age-related maculardegeneration

https://pubmed.ncbi.nlm.nih.gov/11483088/

Past Podcast Episode on "Evolutionary Mismatch"

Evolutionary Mismatch – A nod to our friends in the Amazonthe Tsimane people in all their wisdom

⁠https://open.spotify.com/episode/3xTi2oKVXUhpZxWGCl99vn?si=PQdecXMiRbOcQaBmh5b7XQ⁠

In this 141st episode I sit down with Dr. Eric Schulte. Eric is a doctor of physical therapy and runs a private practice called Movement Academy here in San Diego, CA.

I got to know Eric recently and have had a few conversations that let me know he was someone I wanted to have on the podcast. You see, there is PT, and then there is that next level PT. I feel that Dr. Eric embodies the latter.

In this episode we discuss topics like physical therapy training/education, insurance-based models vs. out-of-pocket approaches to care, how there is often a link between physical injury and deeper underlying concepts around emotions and mental health, how a knee condition might actually be an ankle condition in disguise, the difference between movement and exercise, how improving movement contributes to higher levels of wellness and longevity, and and much more.

If you are interested in learning more about what Dr. Eric has to offer you can find him here:

Website: mymovementacademy.com 

IG: movementacademy__

Email: dreric@mymovementacademy.com

In this 140th episode I discuss some important concepts around testosterone replacement therapy in men. This topic came up as a result of a conversation I had recently with a colleague where I talked about some of the more radical concepts I have seen as a result of higher levels of testosterone therapy.

There is of course a time and a place for just about anything... And testosterone or any other hormone replacement therapy is not something that I feel is wrong by any means. But I do believe that it is a 'can of worms' in a lot of ways. It can be hard to get it right. As I discussed in a previous episode, hormone levels do not necessarily equal "hormone effect." There is much more to the equation.

In this episode I will discuss some of the basic physiology of how testosterone is produced and managed naturally. Knowing this helps us understand how and why hormone replacement may or may not be ideal, and how problems can occur.

I discuss my time spent shadowing an HRT doctor (MD) during my Doctorate program, and where I saw first hand some of the unfortunate side effects of high testosterone. And yes... It involves the testicles!

If you haven't listened to my past episode on Hormones, check it out here... In this episode I discuss how hormone levels do not equal hormone effect. Meaning, there is much more to the story. So chasing a particular effect like larger muscles, less hot flashes, more vitality, etc. and getting hormone levels higher and higher could lead to unfortunate effects on your health. This episode explores such concepts:

https://open.spotify.com/episode/0UysAMJ8G5w8dtLgaa8s7q?si=uvXhtyjqScSusg4FGyA1dA

In this 139th episode I sit down with Chase Zittrauer, Rep for Cyrex Labs, to discuss a new test called the BiomeBurden Complete. This ground breaking lab panel looks at the gut microbiome (bacterial) and mycobiome (yeast/fungus) as seen through the lens of the immune system.

By that I mean, given the status of those little microorganisms living in your gut, this lab test looks at how your immune system observes the situation. If for example there is a Candida overgrowth, your immune system may or may not be reacting to the situation the same as the next person. But for many, antibody production against Candida, for example, can lead to immune reactions elsewhere in the body! So gut does not really mean just the gut.... It can mean any other part of your body! And if you are in the autoimmune population, this can be a very important detail to your health and wellness.

Consider the person who has been to a ton of doctors, had a bunch of tests run, and still has persistent and "strange" symptoms. Well, there could be a lurking immune cross-reactivity concern at play between organisms in your gut and self-tissues elsewhere int he body. The BiomeBurden Complete can be a great way to start to peel back the layers of the onion so to speak and get to those kinds of immune-driving mechanisms.

Chase and I discuss this concept in detail, and more... Much much more. I really enjoyed this conversation and I hope you will as well!

You can check out everything that Cyrex Labs has to offer here:

https://www.cyrexlabs.com/CyrexTestsArrays/tabid/136/Default.aspx

And by all means, if anything here calls to you, please reach out. I love this stuff and am happy to help!

In this 138th episode I record from home with my wife Debbie to discuss how it is living with a gluten free member of the family.

We discuss the transition from a normal diet to providing the family with a 100% gluten free diet after I discovered my significant gluten sensitivity condition. There were some struggles, there were some discoveries, there was even benefits for the entire family.

Debbie and I talk about how it was to make these changes, and even discuss some really yummy meals/dishes that we picked up along the way and that we enjoy as a family today!

I hope you enjoy this heart-to-heart discussion with my wife & life partner Debbie who has supported me through so many things, not just my transition into a gluten free life. May our discussion help you and your family if a gluten sensitivity or Celiac Disease diagnosis comes your way. I think that you will get from our chat that it isn't all that bad. In fact, life is still full of yummy things!

And as promised, here is a link to my website where I have posted some really awesome gluten free yummies!!! (Not blood sugar friendly however. But the waffles... Oh my goodness, the waffles...)

https://functionalmedicine-sandiego.com/search?q=gluten%20free&f_collectionId=5796659c2994ca1f5d9e72da

Find Me Gluten Free Website and App:findmeglutenfree.com

In this 137th episode I pop in quickly to share a recent medical experience I had with dermatology. In keeping with my interest in not only detailing what I consider cool and important medical information, riffing and philosophizing on the human experience, and offering some creative writing... I feel obligated to share my personal medical experiences. Because chances are that you have had or will have some similar experiences of your own!

This time around I had a few experiences in dermatology. I had a suspicious mole removed and then a follow up procedure to get the rest. Happy to say it wasn't skin cancer, but it was close.

Listen in for what happened, and how I feel about the situation. Long story short, I'm happy I submitted to such a procedure. But holy hell... It felt like I was shanked an a freaking alley!!

In this 136th episode we’re taking a another look at the widely accepted belief that saturated fat and cholesterol are the primary causes of heart disease.

Despite the well-known risks and the skyrocketing use of statins—prescription rates have increased significantly over the past decade—heart disease remains the leading cause of death in the United States. Every 40 seconds, someone in the U.S. experiences a heart attack, and over 900,000 Americans die from cardiovascular issues each year.

In this episode, we’ll explore the complex and often overlooked mechanisms that contribute to coronary artery disease. Beyond cholesterol, factors such as chronic inflammation, autoimmune responses, hormonal imbalances, toxin exposure, genetics, and infections play vital roles. We’ll focus on certain infections—like H. pylori, cytomegalovirus, and COVID-19—that can silently influence vascular health by causing inflammation, autoimmunity, and tissue damage, often without obvious symptoms.

Why do infections matter? Because they can initiate or sustain vascular inflammation, damage arterial walls, and contribute to plaque buildup over time. Understanding these hidden contributors opens the door to more personalized and effective prevention strategies. We’ll discuss how to identify infections through testing, and explore various treatment options—from targeted antibiotics and herbal support to lifestyle changes such as exercise, diet, and stress reduction—that can help address these underlying issues.

Join us as we challenge the conventional view and uncover what truly drives heart disease. If you or someone you care about is dealing with cardiovascular concerns, this episode offers new insights that could transform how you view prevention and treatment—because heart health is about much more than just cholesterol.

Citations:

Statins utilization trends and expenditures in the U.S. before and after the

implementation of the 2013 ACC/AHA guidelines

https://www.sciencedirect.com/science/article/pii/S1319016423000841?via%3Dihub

Helicobacter pylori and cardiovascular complications: a mechanism based review on

role of Helicobacter pylori in cardiovascular diseases

https://pmc.ncbi.nlm.nih.gov/articles/PMC5390428/

Cytomegalovirus Localization in Atherosclerotic Plaques is Associated with Acute

Coronary Syndromes: Report of 105 Patients

https://pmc.ncbi.nlm.nih.gov/articles/PMC3405798/

COVID-19 in the Initiation and Progression of Atherosclerosis: Pathophysiology During

and Beyond the Acute Phase

https://www.jacc.org/doi/10.1016/j.jacadv.2024.101107

Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a

possible link to an increase in autoimmune diseases

https://pubmed.ncbi.nlm.nih.gov/32461193/

In this 135th episode I address my thoughts on turning 50 years old. Hint hint... It is good. ;-)