Explorez tous les épisodes du podcast The NatureCity Podcast
| Titre | Date | Durée | |
|---|---|---|---|
| Could Astaxanthin Help Your Body Use More Fat for Fuel? | 18 sept. 2026 | 00:08:35 | |
A new AstaReal astaxanthin study looked at something researchers hadn't isolated before: not whether astaxanthin supports exercise performance, but which fuel your muscles reach for while you're exercising.
20 recreationally active women completed a randomized, double-blind, placebo-controlled, crossover-design study — each woman served as her own control. After taking 12 milligrams of AstaReal astaxanthin daily for two weeks, their respiratory exchange ratio (RER) during a 30-minute cycling test was significantly lower than on placebo, meaning their bodies shifted more toward using fat and less toward carbohydrate to fuel the exercise. Heart rate, blood lactate, and perceived effort didn't change — the women weren't working harder or easier, but how their muscles fueled the work was different.
Carl breaks down what that shift actually means (and, just as importantly, what it doesn't mean — this was not a weight-loss study, and endurance wasn't tested here), why most previous astaxanthin-and-fuel research was conducted in men, and how this connects back to one of his favorite astaxanthin stories: salmon swimming hundreds of miles upstream to spawn without eating.
At NatureCity, our TrueAsta astaxanthin supplement uses the same AstaReal branded astaxanthin used in this study — two soft gels provide the 12-milligram daily amount studied here. Timestamps[00:00] Introduction [00:08] The reversal: why "burn more fat" isn't a weight-loss claim here [00:43] Two fuel tanks: carbohydrate vs. fat during exercise [01:19] The new study: 20 women, crossover design, 12mg AstaReal daily [02:13] What RER measures and why it matters (clean take begins after retake at [03:00]) [02:50] The result: lower RER on astaxanthin vs. placebo [03:16] What this does NOT mean [03:49] Heart rate, blood lactate, and perceived effort unchanged [04:15] Metabolic flexibility, explained with the two-gas-tank analogy [05:03] Why this study focused on women, not men [05:40] Callback to Episode 128 and the salmon-swimming-upstream story [06:17] Salmon, fat stores, and the "salmon aren't humans" caution [06:40] Prior astaxanthin-and-exercise research: soccer players, cyclists, resistance training [07:39] TrueAsta: used same AstaReal astaxanthin in a study [08:02] Closing thoughts | |||
| Why Living Longer Isn't The Real Goal Of Aging | 11 sept. 2026 | 00:44:52 | |
We live longer than people did in the 1950s, but many of those extra years can come with frailty and a loss of mobility and independence. Our health goal shouldn’t be to just live longer – you want those extra years to be good years. One powerful nutritional ally that can help support healthy aging is the pomegranate fruit. Carl Pradelli sits down with two Euromed scientists to review the latest research with their Pomanox P30 extract, which is made using the whole pomegranate fruit. WHAT YOU'LL LEARN This conversation moves the focus from lifespan to healthspan, the idea that quality years matter as much as total years. Carl Pradelli, CEO and Co-Founder of NatureCity, talks with Dr. Andrea Zangara, scientific communications advisor at Euromed, and Silvia Mont, a registered pharmacist and nutritionist who is part of the Euromed scientific marketing team, about the numerous biological systems that Pomanox P30 can support and recent findings about the extract’s impact on several blood biomarkers linked to healthy aging and longevity. Some of these include Urolithin A, AhR activity and IGF-1 levels. You will also hear how Pomanox P30 can help support heart and cardiovascular health. The discussion covers blood flow, nitric oxide, and maintaining flexible arteries. It closes on what studies show for skin appearance, muscle recovery, and staying functional as the years add up. EPISODE SUMMARY Aging well is not about chasing a longer number of years. Dr. Andrea Zangara opens by naming the shift researchers have already made: the focus is on healthspan, living well, not just living longer. As guest Silvia Mont notes, there is no single magic bullet, so a holistic approach is the most effective one. The episode focuses on the pomegranate fruit, a stable of the Mediterranean diet, and how the Pomanox P30 whole pomegranate extract stands out as a well-validated example of a dietary addition that can support healthy aging. The guests explain how a standardized whole pomegranate fruit extract works with the body rather than around it. Instead of shortcutting the body's own processes, it supplies compounds the body already knows how to recognize, digest, and transform through the gut microbiome. That framing, a physiological approach over a single molecule, is the heart of the episode. Carl and his guests walk through the biological systems pomegranate polyphenols touch to help support healthy aging and longevity: gut bacteria that convert precursors into urolithins (stimulate cellular energy and the “cleanup” process known as mitophagy), AhR cellular protein activity (helps detox, immunity and metabolism), and keeping the vital IGF-1, protein hormone in a healthy range. Blood flow gets its own segment. Carl explains pulse wave velocity in plain terms: a blood pressure pulse travels faster through stiffer arteries and slower through flexible ones, so a slower reading is what you want. The guests connect flexible arteries and healthy nitric oxide production to better circulation, which touches brain performance, energy, and recovery. A healthy Inflammation response ties it together. Dr. Zangara describes “inflammaging”, the low-grade inflammatory state that builds quietly with age and often escapes a normal health test. Carl adds a point the podcast returns to often: inflammation protects us, and the challenge as we age is often in resolving it, cleaning up after the threat is gone, and getting back to normal function. The episode ends on beauty from within, exercise recovery, and a consumer-facing summary from Silvia: it is not about magic, it is about science. The takeaway for a general listener is simple. Support the whole system, give the body what it already knows how to use, and pair it with a healthy lifestyle. TIMESTAMPS
If this helped you think differently about aging well, like the episode and subscribe on YouTube so the next conversation finds you. Listening on the go? We are on Apple Podcasts and Spotify. LINKS & RESOURCES
#HealthyAging #Healthspan #Longevity #Pomegranate | |||
| Tired at Work? Try This Instead of More Coffee | 04 sept. 2026 | 00:10:47 | |
A newly published study compared EnXtra directly with caffeine — and what happened after one-hour and at the five-hour mark is worth understanding before you reach for another cup. Subscribe for research-backed conversations on supplements and health.
Carl Pradelli, CEO and Co-Founder of NatureCity, walks through a May 2026 study on EnXtra, the reason TrueMind was formulated without caffeine, and what he means by calming energy.
WHAT YOU'LL LEARN - How this study was designed and what makes its comparison unusual - What happened at 1, 3 and 5 hours in the four study groups - The specific measurement where caffeine-only performance fell below baseline - The combination that sustained alertness and mental energy the longest - Why TrueMind was built without caffeine and 3 other nutrients instead - What Carl means by calming energy, and the daily routine he uses
Most conversations about mental energy start and end with caffeine. Carl opens this episode with a simple question: when you are trying to maintain alertness for several hours or across the whole workday, is more caffeine always the best answer? A new study published in May 2026 in the Open Access Journal of Clinical Trials helps clarify answers to that question. It compared EnXtra directly with caffeine, not just with a placebo.
EnXtra is a standardized extract of Alpinia galanga — the plant related to ginger that is sometimes called Thai ginger or galangal. It has been studied for its effect on mental alertness and energy without acting as a stimulant. The study was randomized, double-blind and placebo-controlled, and it ran in two stages: an acute crossover with 128 people, then a 28-day arm with 127 people. Participants were healthy adults between 18 and 40, they were habitual caffeine consumers, and their sleep was deliberately restricted so the researchers were testing under real-world mental fatigue rather than fresh-from-eight-hours conditions.
The study had four arms: 300 milligrams of EnXtra, 200 milligrams of caffeine (roughly two cups of coffee, so caffeine was not being given a handicap), 300 milligrams of EnXtra combined with 200 milligrams of caffeine, and a placebo. Alertness was measured at baseline and again at one, three and five hours. Caffeine did what caffeine does — it worked, primarily at the one-hour measurement. By three and five hours those effects were much more limited. EnXtra continued to show benefits at later measurements, and at five hours the combination of EnXtra and caffeine produced the strongest result. On one measure of alertness, caffeine-only performance had actually fallen below where it started — the crash most heavy caffeine users can describe from experience.
Carl is careful about the limits. Sustained attention and psychomotor measurements showed favorable trends with EnXtra but were not consistently statistically significant. It was a fairly young cohort with restricted sleep. He is not extrapolating this study to every aspect of cognitive performance, and he says so on the record. What the study demonstrated most clearly was support for alertness and reduced fatigue, and the ability to sustain those benefits across several hours, which fits earlier research on the ingredient.
The rest of the episode is about why TrueMind was formulated the way it was. Carl explains that TrueMind does not contain caffeine on purpose — most listeners are already getting caffeine somewhere, and stacking more of it was not the goal. Instead, the formula pairs EnXtra with PharmaGABA (a naturally produced form of GABA studied for supporting a relaxed, focused state) and a third standardized ingredient Landkind Salidroside (salidroside is a compound found in the Rhodiola plant), which helps support mental energy while experiencing stress. Carl calls the target state calming energy — awake and alert and focused, but not wired. He closes with the routine he actually uses: tea between seven and eight in the morning, then a serving of TrueMind a few hours later, between ten and eleven.
None of this replaces sleep. Carl says it directly. Get more sleep.
TIMESTAMPS
ABOUT NATURECITY NatureCity is hosted by Carl Pradelli, CEO and Co-Founder. Carl started the company over 20 years ago with his wife Beth. The show covers the ingredients, research and formulation choices behind NatureCity supplements. Learn more about True Mind: https://www.naturecity.com/products/true-mind?srsltid=AfmBOooMZNw1C7dDQun7l4vBDPv6ylnm8V1fvLJq2ZlTfFoiD0v9S2HX #NatureCity #TrueMind #EnXtra #MentalEnergy | |||
| How Eating the Rainbow Actually Protects Your Cells as You Age | 21 août 2026 | 00:15:31 | |
You've heard that antioxidants fight free radicals. Carl Pradelli, CEO and Co-Founder of NatureCity, goes one step deeper: there isn't one kind of free radical, and no single antioxidant can handle them all.
WHAT YOU'LL LEARN Carl explains why "free radicals" are really a whole spectrum of reactive compounds, each with different chemistry, locations, and challenges. He walks through how the body defends itself with a network of nutrients – both from diet and internally produced antioxidants – working as a relay team, not a single fighter.
You'll also hear why breadth beats brute force in antioxidant nutrition, how different colorful plant foods deliver different beneficial compounds, and what a large flavonoid study found about antioxidant variety and health outcomes. Carl closes with the same philosophy behind the TrueBerry7 formulation This episode fits anyone thinking about how they age and how they choose supplements, with research kept in its proper framing throughout.
EPISODE SUMMARY
Carl Pradelli hosts this episode of the NatureCity podcast on antioxidant nutrition and why the popular picture of it is too simple.
The core idea: oxidative stress isn't one problem. Cells encounter a range of reactive oxygen and nitrogen species, and different antioxidants have different strengths against them. Carl references his earlier conversation with Dr. Karen Hecht and Dr. Susan Emrahi of AstaReal, who described antioxidants as having different "fingerprints" and capabilities.
He covers direct antioxidant activity versus compounds that help support the body's own internal defenses, the science behind eating a variety of colorful plant foods, and a study of roughly 125,000 adults linking flavonoid diversity to better health outcomes (discussed further in episode 109). The takeaway Carl lands on: think variety, think teamwork, think breadth over brute force.
Use the timestamps below to jump to the sections most useful to you as you listen.
TIMESTAMPS
If this episode helped, like it and subscribe to the NatureCity YouTube channel so you don't miss future episodes. Find us on Spotify and Apple Podcasts. LINKS & RESOURCES
#antioxidants #supplements #healthyaging #NatureCity | |||
| Inflammation Isn't the Enemy - Why The “Cleanup” Process Matters for Healthy Aging | 14 août 2026 | 00:14:01 | |
Most of us treat inflammation as the enemy. Carl Pradelli, CEO and Co-Founder of NatureCity, makes the case that you couldn't stay healthy without it, and how your body finishes an inflammatory response may matter as much (or more) as how it starts. WHAT YOU'LL LEARN Inflammation has a beginning, a purpose, and an ending. This episode focuses on that ending, the active biological process researchers call resolution. Carl explains why resolution isn't inflammation simply fading on its own, and why some of that cleanup machinery may become less efficient as we age. You'll learn what specialized pro-resolving mediators (SPMs) like resolvins, protectins, and maresins do, and how omega-3 fatty acids EPA and DHA supply raw materials the body uses to make them. Carl covers the lifestyle factors that keep low-grade inflammation simmering, including visceral fat, poor sleep, chronic stress, smoking, and being sedentary. He closes with three researched nutrients that support the healthy inflammation response and how each works: omega-3s (EPA and DHA), curcumin from turmeric, and PEA (Levagen+) found in NatureCity's TrueJoint FLX formula. EPISODE SUMMARY Carl Pradelli, CEO and Co-Founder of NatureCity, opens with a reframe: inflammation isn't a mistake your body makes, it's an essential defense and repair system. Cut a finger, fight an infection, or exercise, and an inflammatory response is part of how you heal, respond, build muscle, and adapt. The problem starts when that response becomes excessive, lingers too long, or doesn't resolve once its job is done. To make it concrete, Carl uses a kitchen-fire analogy. When there's a fire, you want firefighters to rush in, break a door or window if needed, and spray water. You don't complain about the mess in that moment because you need them there. But once the fire is out, the hoses have to stop, the damaged material has to be cleared, and rebuilding has to begin. That second phase is resolution, and Carl describes it as an active process in which the body produces signals that stop the response, clear damaged cells, and shift tissue from defense mode into repair. The episode connects this to aging. Persistent low-grade inflammation, sometimes called “inflammaging”, becomes more common as we get older. Newer research adds a layer: we may not just be triggering more inflammatory responses with age - we may also become less efficient at resolving them. Carl introduces specialized pro-resolving mediators (SPMs) and the cleanup work of macrophages, then keeps the science practical with a single takeaway: putting out the fire is not enough, someone has to clean up the mess. Carl grounds the discussion in what people can influence. Lifestyle matters tremendously, from visceral fat and metabolic health to smoking, chronic stress, poor sleep, and being sedentary, along with a diet built on minimally processed foods. Supplements, he stresses, should support those fundamentals rather than replace them. He then walks through three researched ingredients working through different mechanisms toward the same goal. Omega-3s EPA and DHA supply building blocks for pro-resolving mediators, with human studies showing changes in circulating lipid mediators involved in inflammation and resolution. Curcumin, the key compound in turmeric, has been studied for modulating inflammatory signaling and oxidative stress, with favorable effects on markers including CRP, TNF-alpha, and IL-6. PEA (Levagen+) in NatureCity's TrueJoint FLX is a lipid signaling molecule the body already makes to help regulate inflammatory and discomfort responses. Carl ends with a clear note of care: persistent, severe, or unexplained inflammation isn't something to self-treat, and it deserves evaluation by a healthcare provider. His closing line ties the science back to the analogy: inflammation isn't the enemy, and healthy aging depends on a response that has a beginning, a purpose, and an ending. TIMESTAMPS
If this changed how you think about inflammation, like the episode and subscribe to the NatureCity YouTube channel for more researcher-formulator conversations from Carl Pradelli. You can also follow along on Apple Podcasts and Spotify. LINKS & RESOURCES
#inflammation #omega3 #healthyaging #curcumin #NatureCity | |||
| Bigger Doses Don’t Always Make Better Supplements | 31 juil. 2026 | 00:14:46 | |
One bottle says 500 milligrams. Another says 1,000. Most of us reach for the bigger number, assuming it works better. After almost 25 years developing supplements, Carl Pradelli explains why that instinct steers shoppers wrong more often than they realize (and supplement companies take advantage of this). WHAT YOU'LL LEARN Carl Pradelli, CEO and Co-Founder of NatureCity, walks through 6 reasons why a bigger dose doesn’t necessarily make for a better supplement. Researchers don’t start studies by asking “what’s biggest dose we can fit into a capsule?” Instead, they ask a different question – “what’s the smallest dose that consistently produces the desired result?” Your body isn’t impressed by big numbers on a supplement label – it responds to nutrients it can actually absorb, utilize and put to work. You'll learn why a better ingredient beats a bigger dose, and why absorption, standardization, and delivery systems often matter more than the milligram count on the front of the bottle. Carl uses named, studied ingredients to show the pattern in action, then leaves you with three questions to ask the next time you compare two bottles. This episode fits Carl's researcher-formulator lane: mechanism first, research-framed throughout, and built for anyone who wants to shop for supplements with more confidence. EPISODE SUMMARY The big idea drives the whole episode: the biggest number on the label doesn't automatically make it the better supplement. Carl builds the case of why it’s more desirable to seek out ingredients that science shows work better and help your body make use of what you are taking. He moves through a series of studied ingredients, each illustrating a different reason a smaller dose can win: a better ingredient, better metabolism, better delivery, a different mechanism, better absorption, and better standardization. Resveratrol, berberine, omega-3 fish oil, collagen, magnesium, and ashwagandha each carry one lesson in that chain. Carl closes with a clear caveat and a practical tool. Smaller isn't always better either; every nutrient has its own effective range, and the right dose depends on the person. The goal is the right dose, backed by the right research. TIMESTAMPS
If today's episode changes the way you look at supplement labels, subscribe to the YouTube channel so you don't miss future episodes. You can also follow along on Spotify and Apple Podcasts. LINKS & RESOURCES
#supplements #resveratrol #biotin #NatureCity | |||
| The Best Form of Magnesium for Sleep, From a Supplement Formulator | 24 juil. 2026 | 00:10:58 | |
Magnesium relaxes muscles, but that is only part of the story. Carl Pradelli, CEO and Co-Founder of NatureCity, explains how magnesium supports the nervous system, the stress response, and the brain's ability to settle down at night. WHAT YOU'LL LEARN
EPISODE SUMMARY Carl Pradelli, CEO and Co-Founder of NatureCity, opens this episode with a small moment at home: mixing TrueMagnesium at night, he found himself thinking about how many processes in the body magnesium touches, and how it likely supports sleep in more ways than people assume. That thought frames the whole conversation. Most people connect magnesium and sleep through one idea, muscle relaxation. Carl acknowledges that reason is real and shares an early NatureCity memory of helping his grandmother with nighttime cramps. But he moves quickly to the more interesting part of the story: magnesium is more than a muscle mineral. It plays roles in the nervous system, the stress response, and the brain's ability to settle down when the body is getting ready for sleep. Magnesium is involved in over 300 processes in the body, and a lot of people are not getting enough. When intake is less than ideal, the body may have a harder time doing many things well, including winding down at night. Carl is careful to draw a line here: magnesium is not a sleeping pill, not a sedative, and does not force sleep. He frames it as a supportive sleep nutrient, not a knockout agent, and that is part of what he likes about it. From there the episode walks through what magnesium supports. A calmer, better-regulated nervous system matters because many sleep problems today are neurological and stress-related, driven by a body and brain that struggle to shift out of a stimulated, alert state. For good sleep to happen, the body needs to transition from go mode into a more relaxed, restorative mode, and magnesium helps support that transition through normal neurotransmitter activity and the conditions the body needs to move toward sleep readiness. Carl then turns to stress and sleep, which he describes as tightly connected in a cycle: high stress hurts sleep quality, and poor sleep leaves the body less resilient to stress the next day. Magnesium does not erase stress, and no supplement can remove what is happening in your life, but it may help support the body systems involved in handling stress in a healthier way. Carl explains a common consumer mistake: assuming all magnesium supplements work the same way. Magnesium oxide is common because it is inexpensive, contains a high percentage of elemental magnesium, and fits easily into capsules, yet it is one of the poorer absorbed forms and more likely to cause gastrointestinal effects at higher amounts. For evening use, he prefers magnesium bisglycinate chelate, which is better absorbed, better tolerated, and bound to glycine, an amino acid that may add its own calming, sleep-supportive layer. He closes with why NatureCity made TrueMagnesium as a drink powder rather than a capsule: pure magnesium bisglycinate chelate is bulky and fluffy, so a powder delivers a more meaningful amount, with each scoop providing 200mg. Carl notes that magnesium is foundational, and for a highly overstimulated brain or elevated evening cortisol it may work best as part of a broader sleep support system. Even on its own, he argues, magnesium deserves more respect in the sleep conversation. TIMESTAMPS
If this helped, like the episode and subscribe to the NatureCity YouTube channel so you don't miss future episodes. You can also listen on Apple Podcasts and Spotify. LINKS & RESOURCES
#magnesium #magnesiumforsleep #sleepsupport #naturecity #supplements | |||
| Resistant Starch: The Most Overlooked Fiber for Your Gut Microbiome | 17 juil. 2026 | 00:11:15 | |
Not all fiber does the same job. Resistant starch is the type of fiber most modern diets have largely stripped out, and research suggests it may be one of the nutrients your gut microbiome misses most. Carl Pradelli explains what it is and why it matters. What You'll Learn:
A lot of people know fiber is important. Fewer realize that not all fiber is the same. In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, makes the case that resistant starch may be one of the most overlooked nutrients missing from diets in the 21st century. For most of human history, people regularly ate starchy plants that naturally contained resistant starch, which gave the gut microbiome fermentable fuel. Modern food processing, refinement, and cooking practices have steadily removed much of it. Current intake is estimated at only about 4 grams per day across the United States and Europe, while 15 to 20 grams per day is often cited for supporting bowel, gut, and metabolic health. Carl explains what makes resistant starch unique. It resists digestion in the small intestine and reaches the large intestine intact, where beneficial microbes can ferment it. That gives it qualities of both insoluble and soluble fiber. Research suggests this fermentable fiber may selectively feed beneficial bacteria, including Bifidobacterium and Akkermansia. Akkermansia is drawing particular research interest for metabolic health and healthy blood sugar metabolism. Studies suggest it may help support healthy GLP-1 levels and help the body use insulin more efficiently, and it appears to play a role in protecting the gut lining and gut barrier function. Carl walks through additional research areas discussed for a low-dose resistant starch called Solnul that can deliver key benefits with just 3.5 grams per day. These include supporting a healthy inflammation response in the gut, consistent stool quality, intestinal barrier function, nutrient absorption, the gut-skin connection, and broader metabolic markers. Every claim stays in research framing. The takeaway is practical. Resistant starch is a fermentable fiber the modern diet provides far less of than it once did and filling that gap at a sensible daily dose with Solnul may be a simple way to support the gut microbiome. NatureCity features this low-dose resistant starch ingredient in its advanced TrueDYB digestive formula. Timestamps:
If this was helpful, like the video and subscribe to the NatureCity YouTube channel so you do not miss future episodes on gut and microbiome health. LINKS & RESOURCES Learn more about resistant starch and TrueDYB: naturecity.com. #ResistantStarch #GutMicrobiome #Akkermansia #MetabolicHealth #GutHealth | |||
| Beyond Melatonin: Supporting Real, Restorative Sleep | 02 juil. 2026 | 00:12:30 | |
Most sleep supplements were built around one idea: make you sleepy. But if you have ever felt tired but wired at bedtime, you already know that making yourself drowsy does not guarantee a good night's sleep. In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, explains why modern sleep support has to do more. Carl co-founded NatureCity over 20 years ago with his wife, Beth, and the company has since served more than 500,000 Americans. Poor sleep is rarely just a bedtime problem. It is often a brain overstimulation problem, a stress and cortisol problem, and a circadian rhythm problem at the same time. WHAT YOU'LL LEARN Why sleep quality matters as much as the number of hours you sleep, and why the best sleep supplements support your sleep biology instead of simply forcing drowsiness. Carl walks through the three systems better sleep support should address: a calmer brain, a healthy stress response, and the body's own circadian rhythm. THE THREE-SYSTEM MODEL FOR BETTER SLEEP First, helping the brain unwind naturally. L-theanine, an amino acid found in green tea, supports calming neurotransmitter activity, including GABA, and promotes relaxed alpha brainwave activity, helping the brain transition into a calmer state without acting like a sedative. TruZzzs uses Suntheanine L-theanine. Second, supporting a healthy stress response. Cortisol is supposed to rise in the morning and gradually come down by evening, but when stress keeps it elevated too long, sleep quality can suffer, and not just your ability to fall asleep, your actual restorative sleep. TruZzzs uses Shoden ashwagandha, a form whose key compounds can stay in the bloodstream for nearly 24 hours, offering round-the-clock support from one dose. Third, supporting the body's own circadian rhythm and evening melatonin biology. Rather than overriding the system with synthetic melatonin, Affron saffron extract helps support the enzymes in the pathway that converts the amino acid tryptophan into melatonin, helping support the body's own evening melatonin production. WHAT TO EXPECT WITH TruZzzs Everyone's experience differs, but Carl outlines a week-by-week timeline: easier to fall asleep in the first one to two weeks, longer time in deeper sleep cycles after three to four weeks, and waking up more refreshed after five to six weeks. A sleep tracker such as a Fitbit or Oura Ring can help you measure the change. LEARN MORE Visit naturecity.com to learn more about TruZzzs or to reach out with any questions. Educational note: This content is for educational purposes only and is not medical advice. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Talk with your healthcare provider before starting any new supplement. #SleepSupport #BetterSleep #Ashwagandha #SleepQuality #Melatonin | |||
| Calcium Isn’t the Problem. Mismanaged Calcium Is. | 22 juin 2026 | 00:10:02 | |
Most people meet vitamin K2 through bone health. The less known story is what it does for your arteries. Subscribe for science-backed healthy-aging answers from Carl Pradelli.
Most of the vitamin K in your diet is K1, not K2, and the two do not behave the same way in the body. That distinction is the whole episode. Carl Pradelli, CEO and Co-Founder of NatureCity, walks through why vitamin K2 in the MK-7 form may be one of the most overlooked nutrients in the healthy-aging conversation, and why its role goes well beyond bone density into vascular health and arterial flexibility.
The mechanism is the part most people never hear about. Vitamin K2 activates two vitamin K-dependent proteins: Matrix Gla protein, which helps keep calcium out of artery walls and soft tissue, and osteocalcin, which helps bind calcium into bone. Carl frames it in one line: vitamin K2 helps the body put calcium where it belongs and keep it out of places where it does not. The problem was never calcium itself. The problem is mismanaged calcium, and mismanaged calcium is what can drive vascular calcification, reduced blood vessel elasticity, and arterial stiffness as you age.
Diet rarely closes the gap. Research on the different vitamin K forms show that MK-7 carries a much longer half-life than other vitamin K forms, but MK-7 is typically a very small part of our diets – unless you’re eating fermented foods regularly. That is why Carl points to the best researched MK-7 form for supplements, MenaQ7, which is used in NatureCity’s TrueK2D3 alongside vitamin D3, and in TrueOsteo+ alongside vitamin D3, plant calcium and magnesium for broader bone and vascular support.
He also references the work of Dr. Leon Schurgers from Maastricht University in the Netherlands, a leading vitamin K2 researcher who describes the loss of independence at age 80 as something that often begins decades earlier. Several published placebo-controlled research studies demonstrate how vitamin K2 can support vascular health and blood vessel elasticity. For healthy adults, the research suggests taking 180 micrograms of MenaQ7 vitamin K2 daily. Carl is careful to keep this in research framing: vitamin K2 doesn’t work in isolation – It’s part of a system with vitamin D3 and other nutrients like magnesium that work together to support healthy aging. WHAT YOU’LL LEARN
TIMESTAMPS 0:00 K2 Is More Than a Bone Nutrient 1:20 How Vascular Calcification Can Age You 2:07 Dr. Schurgers on K2 and Aging 2:50 Why Diet Falls Short on K2 4:03 Matrix Gla Protein and Osteocalcin 5:08 What MK-7 and MenaQ7 Really Are 5:55 The 3-Year Blood Vessel Study 8:03 K2 and Supporting Nutrients ABOUT NATURECITY NatureCity was founded by Carl Pradelli, CEO and Co-Founder, with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served, NatureCity is committed to quality, honesty, and results. TrueK2D3: https://www.naturecity.com/products/truek2d3-plant-based-vitamin-k2-vitamin-d3?_pos=1&_psq=truek&_ss=e&_v=1.0 TrueOsteo+: https://www.naturecity.com/products/true-osteo?_pos=1&_psq=trueosteo&_ss=e&_v=1.0 Learn more: https://www.naturecity.com/ #VitaminK2 #MK7 #VascularHealth #HealthyAging #MenaQ7 | |||
| Your 1,000mg Magnesium Supplement Could Be 99% the Cheapest Form | 12 juin 2026 | 00:12:59 | |
Some magnesium supplements look impressive on the label — especially those claiming large amounts of magnesium from a “complex” of multiple forms. But when you break down the math, many of these products appear to rely overwhelmingly on magnesium oxide: the cheapest, least absorbable, and often least desirable form for everyday supplementation. In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, runs the label math on a popular magnesium complex, explains how these misleading magnesium blends work, why capsule claims often don’t add up, and how to spot label engineering designed to make a product seem higher quality than it really is. Carl takes you step-by-step through numbers and how he reached the conclusion that a 1,000mg blend with 8 types of magnesium has to be at least 90% magnesium oxide, and could plausibly run as high as 98% or 99%. You’ll also learn why pure magnesium bisglycinate chelate is often a much better option for supporting magnesium levels without unwanted gastrointestinal effects. If you found this episode helpful, please like, subscribe, and share it with someone shopping for a magnesium supplement. WHAT YOU'LL LEARN - Why "proprietary blend" and "magnesium complex" labels can hide what you're actually buying - The capsule math showing why a 1,000mg, 8-form magnesium blend has to be at least 90% magnesium oxide - How much magnesium most adults actually need, and why 1,000mg a day rarely makes sense without a doctor's guidance - Why magnesium oxide is poorly absorbed, with some estimates as low as 4% - What Carl looks for instead: pure magnesium bisglycinate chelate, and why it doesn't fit well in capsules
NatureCity was founded over 20 years ago by Carl and his wife Beth on a commitment to science and ingredient transparency, and has served over 500,000 Americans since. Full chapter breakdown below.
If this helped you read your next supplement label, please like the video and subscribe so you won't miss future episodes. Learn more about True Magnesium: https://www.naturecity.com/products/true-magnesium?_pos=1&_sid=e3fc8b62e&_ss=r ABOUT NATURECITY NatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served, NatureCity is committed to quality, honesty, and results. NatureCity Website: https://www.naturecity.com/ #NatureCity #Magnesium #SupplementLabels #NaturalHealth | |||
| Eggshell Membrane for Joints: 3 Ways It Works (Backed by 16 Studies) | 08 juin 2026 | 00:09:44 | |
Many people reach for glucosamine or chondroitin when they think about joint supplements. The ingredient with some of the strongest human research behind it comes from a part of the egg almost everyone throws away: the thin membrane inside the shell.
Carl Pradelli, CEO and Co-Founder of NatureCity, breaks down natural eggshell membrane, known as NEM, and why it may be one of the most underappreciated ingredients in joint health. Subscribe for science-backed health education every week.
Eggshell membrane is different from the single-compound supplement ingredients most people know. It is a naturally occurring matrix that contains many of the same compounds found in the body's own connective tissue, including collagen, hyaluronic acid, chondroitin sulfate, and other glycosaminoglycans, along with a small amount of glucosamine.
There is also a strong origin story. The founders of Stratton Nutrition saw that the shells and membranes from commercially cracked eggs were going to landfills, and developed a patented steam-and-vibration process to separate the membrane and concentrate it into a joint-health powder. NEM is natural, food-sourced, and upcycled.
Carl walks through why the research stands out. To date, 16 published studies have investigated NEM for both safety and efficacy, at a practical dose of just 500 milligrams a day. Research has shown improvements in joint comfort and flexibility in as little as seven to 10 days, which is faster than many joint ingredients ask people to wait, with benefits that can continue to build over continued use.
He also explains how NEM appears to work in more than one way. First, it supplies key building blocks found in joint tissue. Second, research suggests it may support a healthy inflammatory response, including supporting healthy levels of markers such as C-reactive protein (CRP).
Third, and most interesting to Carl is how NEM helps protect healthy cartilage. Urinary CTX-II is a biomarker of type II collagen breakdown. The reduction in urinary CTX- II experienced by many NEM users is considered a sign that cartilage breakdown is being reduced. That points to NEM supporting the structure of healthy cartilage, not just how joints feel.
NEM is a win for the environmental too: it takes the membranes from about 12 eggs to make a single 500 milligram dose, and to date over 250 million pounds of eggshells have been diverted from landfills to make the beneficial NEM powder.
Finally, Carl makes the case for proactive joint support. As he puts it, the smartest joint strategy is not to wait until you’re hurting. NEM and the other key ingredients in TrueJoint FLX can help you stay active and recover from exercise while promoting longer term joint health.
NatureCity was co-founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements, and has served over 500,000 customers over its 20+ year history.
This conversation connects to joint health, cartilage support, collagen, hyaluronic acid, inflammation, and healthy aging.
WHAT YOU'LL LEARN
ABOUT NATURECITY NatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served, NatureCity is committed to quality, honesty, and results. Learn more about TruJoint FLX: https://www.naturecity.com/products/true-joint-flx?srsltid=AfmBOorusQkktdS2cuC0BNfj2APilraO-bMq2yWmKJolYRSpJf-xixo- This content is for educational purposes only and is not intended as medical advice. Consult your healthcare provider before starting any supplement. #NatureCity #JointHealth #EggshellMembrane #NaturalHealth | |||
| Amla Is Trending for Hair—But Here's What It Actually Does Best | 21 mai 2026 | 00:09:32 | |
Amla is everywhere in haircare right now—but what does the science actually support? Carl Pradelli breaks down what this trending ingredient does best. WHAT YOU'LL LEARN
You've probably noticed amla showing up more in haircare conversations—scalp health, hair strength, even hair growth. But should you be taking an amla supplement for your hair?
In this episode, NatureCity CEO and Co-Founder Carl Pradelli gives you a straight answer. While there is some early human evidence suggesting oral amla may support hair health in women, the stronger and more established science points somewhere else entirely: blood circulation and cardiovascular health.
Carl explains how Capros, the high-potency amla extract used in TrueCapros and TruBerry7, has been shown in multiple human studies to support endothelial function, increase nitric oxide production, reduce oxidative stress markers, and support already healthy cholesterol levels. He breaks down what endothelial function actually means, why nitric oxide matters for blood vessel health, and how healthy circulation supports every tissue in your body—including, in theory, hair follicles.
The takeaway? People may discover amla because of the hair trend, but the real value lies in heart and blood flow support. And if hair is also a goal, Carl shares a smarter strategy: pairing TrueCapros with direct hair support formulas like TrueHNS or TrueNuGrow+. TIMESTAMPS
Learn more about Tru Capros, TruBerry7, Tru HNS, and Tru NewGro+ at NatureCity.com. Subscribe to the Nature City Podcast so you never miss an episode! LINKS & RESOURCES
#Amla #HeartHealth #NitricOxide #NatureCity #Capros | |||
| Why Calcium Alone Won't Save Your Bones After 40 | 15 mai 2026 | 00:10:52 | |
Most women don't think about bone health until their 60s or 70s — and by then, bone loss is already well underway. Subscribe to the NatureCity channel for science-backed conversations on supplements, healthy aging, and the research most women never hear. In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, walks through why bone health support has to start earlier than most women realize, why calcium alone won't carry the load, and what bones actually need to keep rebuilding. According to the Bone Health and Osteoporosis Foundation, one in two women and up to one in four men over 50 will break a bone in their lifetime. MedlinePlus notes that bone loss often has no symptoms until the first bone break, and that loss accelerates in the years following menopause. That combination — silent loss and a late wake-up call — is what makes bone health a timing problem before it's a supplement problem. Carl unpacks the biology most people never hear. Bone is not a static structure. It's living tissue, constantly being remodeled by two types of cells: osteoclasts that break down old bone, and osteoblasts that build new bone. Healthy bones depend on the balance between those two processes, and when that balance shifts toward breakdown, bone density and bone strength gradually decline. This is why a single-ingredient calcium supplement falls short. Strong bones require a broader system of nutrients working together — the full orchestra, not the solo performer. That system, as Carl describes it, includes calcium as the foundation, vitamin D to help the body absorb calcium, vitamin K2 to direct calcium to the bone matrix instead of soft tissue, magnesium to support bone structure and the body's handling of vitamin D and calcium, and silica to support the connective-tissue framework that strong bones depend on. The form of calcium matters too. Plant calcium carries additional trace minerals and cofactors that better reflect how the body actually builds bone, compared to standard calcium derived from limestone rock. Movement, strength training, and adequate protein round out a real bone health plan — supplements support the work, but the body still has to do it. For viewers wondering whether they've waited too long, the closing message is the most important: it's never too early, and it's never too late. The ideal time to start supporting bone health is before and around the menopausal transition, when loss accelerates. Meaningful support is still possible at any age. Carl references TruOsteo+ (with Sensoril ashwagandha for stress-related bone protection) and TruOsteo for the core bone-nutrient stack, plus TruK2D3 and TruMagnesium for individual cofactor support. NatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. Over 500,000 customers have ordered from NatureCity since the company was founded over 20 years ago. Timestamps0:00 — Welcome 0:30 — Why most women start bone support too late 3:18 — Bones are living tissue: osteoblasts and osteoclasts 4:36 — The biggest calcium misconception 5:33 — The five nutrients bones actually need 8:17 — Plant calcium versus rock calcium 9:39 — Never too early, never too late About NatureCityNatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served, NatureCity is committed to quality, honesty, and results. LinksShop TruOsteo+: https://www.naturecity.com/products/true-osteo?srsltid=AfmBOoqdCS3b35QyetKdc_Juf8HLdhOrCAzPwTTrBGTGuoIF7e3wbi-t Shop TruOsteo: https://www.naturecity.com/products/trueosteo-advanced-bone-support-no-ash?_pos=2&_sid=3ff954109&_ss=r Shop TruK2D3: https://www.naturecity.com/products/truek2d3-plant-based-vitamin-k2-vitamin-d3?_pos=1&_sid=58df74e56&_ss=r Shop TruMagnesium: https://www.naturecity.com/products/true-magnesium?_pos=1&_sid=4a033ca3f&_ss=r Visit NatureCity: https://www.naturecity.com/ #NatureCity #BoneHealth #WomensHealth #HealthyAging | |||
| Why Taking Collagen Alone Isn't Enough (And the 5 Nutrients Most People Miss) | 08 mai 2026 | 00:09:48 | |
Most collagen advice stops at the supplement aisle. Subscribe for what comes next: https://www.youtube.com/@naturecitysupplements In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, walks through what the body actually does with collagen peptides — and the five nutrients that turn those fragments into actual collagen for healthy skin, hair, joints, and connective tissue. Collagen is the most abundant structural protein in the human body, and it holds together everything from skin and cartilage to tendons, ligaments, bones, and blood vessels. Production declines with age, which is why collagen has become one of the largest categories in supplements for skin, hair, joints, and healthy aging. Reaching for a collagen supplement is a reasonable response. The confusion starts with what happens next. Collagen peptides are not finished collagen. They are fragments — broken-down pieces of collagen protein that the body still has to digest, absorb, and use as raw material before any of it ends up in your skin or joints. That distinction reframes the entire question. Rather than asking whether to take collagen, Carl walks through what the body actually needs to build and maintain it. Vitamin C is non-negotiable for collagen synthesis — without enough of it, the body cannot properly form collagen, which is one reason vitamin C has been linked to skin health and wound healing for as long as nutrition science has existed. Silica, a mineral containing the element silicon, supports the architecture of skin, hair, nails, and connective tissue. Glycine, one of the primary amino acids inside collagen itself, is a major part of its structure. OptiMSM provides sulfur, a key structural element across the connective-tissue matrix, which is why MSM has earned its place in both beauty and joint-health conversations. None of these are alternatives to collagen peptides. They are the building blocks and structural supports that determine whether the peptides you take get used. Building collagen is only half the work. The collagen already in your body is under constant pressure from oxidative stress, UV exposure, an unhealthy inflammatory response, and normal aging — and protecting it matters as much as building more. This is where astaxanthin earns its reputation as one of nature's most powerful antioxidants. The skin cells that produce collagen, called fibroblasts, can have their output reduced or shut down entirely when free radicals attack them. Astaxanthin's antioxidant properties help defend fibroblasts so they can keep producing collagen, while protecting the tissues collagen already holds together. For anyone focused on skin health, joint health, or visible aging, that protective layer is the piece a collagen-only routine misses. Collagen support is a system, not a single supplement. Collagen peptides supply raw material, but vitamin C, silica, glycine, OptiMSM, and astaxanthin do the building, structural, and protective work the body relies on to turn that raw material into healthy tissue. NatureCity's TrueNuGrow+ formula combines collagen with nutrients that support hair, skin, and connective tissue from several angles, and TrueJointFLX uses the NEM eggshell membrane complex — which contains collagen alongside supporting nutrients — for joints, muscles, and surrounding connective tissue. ABOUT NATURECITY NatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. Over 500,000 customers served. LEARN MORE TrueNuGrow+: https://www.naturecity.com/products/truenugrow?_pos=1&_psq=truenugro&_ss=e&_v=1.0 TrueJointFLX: https://www.naturecity.com/products/true-joint-flx?_pos=1&_psq=truejoint&_ss=e&_v=1.0 Visit naturecity.com or contact us with any questions: https://www.naturecity.com/ or customerservice@naturecity.com #NatureCity #Collagen #HealthyAging #Astaxanthin #Supplements | |||
| Why Most Curcumin Supplements Underperform (And the Absorption Fix) | 24 avr. 2026 | 00:10:04 | |
Turmeric and curcumin are not the same thing — and most curcumin supplements are poorly absorbed. Subscribe for more supplement truth from Carl Pradelli. In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, breaks down the real reason so many curcumin supplements underperform: absorption. The milligram number on the bottle is only half the story. What matters is how much your body can actually use. Turmeric is the yellow-orange spice used in cooking. Curcumin is the key compound inside turmeric that research has linked to a healthy inflammation response, joint comfort, cognitive support, immune function, mood balance, and cardiovascular health. Raw turmeric powder only contains about 2 to 5 percent curcumin, which means reaching a meaningful supplemental dose from turmeric alone would require roughly eight grams per day — not practical for almost anyone. Once curcumin is isolated, it becomes poorly absorbed during digestion. That is where many supplement companies mislead consumers. A bottle can list 500 milligrams or even 1,000 milligrams of curcumin and still deliver very little to the bloodstream. A common fix is combining curcumin with piperine, a black pepper extract, but piperine is a foreign absorption enhancer and can raise questions about interactions with other substances. Carl explains why NatureCity uses BCM-95 in True Curcumin. BCM-95 reunites curcumin with turmeric's own essential oils — no foreign enhancers, all from the turmeric plant itself. Just 400 milligrams of BCM-95 has been shown to be equivalent to about 2,500 milligrams of regular curcumin in terms of absorption and sustained presence in the bloodstream. BCM-95 is backed by over 90 published independent research papers and an 18-year track record in 60 countries. He also covers True Joint FLX, which uses TamaFlex — a research combination of turmeric and tamarind seed backed by three separate human clinical studies for joint health. The takeaway for every supplement buyer: look past the milligram number. Ask two questions instead. Is it absorbed? And does the specific extract have human clinical research behind it? ABOUT NATURECITY NatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served across 20+ years, NatureCity is committed to quality, honesty, and results. LINKS True Curcumin: https://www.naturecity.com/products/true-curcumin?srsltid=AfmBOoqm6l-h5VGsz_Ul9npMMuA1LC9--5rXxhP-JSTmflrO97ZLAF3G TrueJoint FLX: https://www.naturecity.com/products/true-joint-flx?srsltid=AfmBOopmkl90VG77ZY8zLnEfuXUhgB_I5E3RHxJ0Fesg46kjQVIBXuHv NatureCity website: https://www.naturecity.com Subscribe: https://www.youtube.com/@naturecitysupplements #NatureCity #Curcumin #Turmeric #JointHealth #Supplements | |||
| Calming Energy: How to Stay Focused Without Caffeine Crashes | 16 avr. 2026 | 00:08:50 | |
Struggling to stay focused without reaching for another cup of coffee? Carl Pradelli, CEO and Co-Founder of NatureCity, explains why stimulation is not the same as focus and how calming energy can transform your productivity.
WHAT YOU'LL LEARN ✓ Why caffeine creates short energy spikes followed by crashes that hurt focus ✓ What "calming energy" means and why it outperforms stimulation for sustained productivity ✓ How enXtra Thai ginger supports alertness for up to five hours without caffeine or sleep disruption ✓ How PharmaGABA promotes calm focus without drowsiness ✓ How LandKind salidroside helps your body handle stress and reduce mental fatigue
This episode of the NatureCity Podcast arrives during Stress Awareness Month, and Carl Pradelli connects the dots between everyday stressors and the focus and energy problems most people try to solve with more caffeine. The issue, Carl explains, is that caffeine delivers short-lived stimulation, not focus. When your stress response system is constantly activated, flooding your body with cortisol and adrenaline, true mental clarity becomes difficult regardless of how much caffeine you consume.
Carl introduces a concept NatureCity calls calming energy: steady, controlled mental energy that supports focus without the jitters, crashes or feelings of anxiety that may come with repeated stimulant use. A calming energy approach is about maintaining consistent focus, steady energy, and a calm mental state throughout the day.
He breaks down three key ingredients that can work together to help create this balanced state. enXtra, derived from Thai ginger, has been shown in placebo-controlled studies to support alertness, improved reaction time and fewer errors for up to five hours. PharmaGABA, a natural form of the neurotransmitter GABA, promotes relaxation and a calm mental state without drowsiness. LandKind salidroside (the key adaptogen compound from the Rhodiola plant) supports cognitive performance under stress and can help protect against mental fatigue.
These three ingredients are the foundation of NatureCity's TrueMind formula, which also includes active forms of key B vitamins for cellular energy production. Carl shares his personal routine of taking TrueMind between 10 and 11 a.m. for sustained productivity through the rest of the business day. SUBSCRIBE to the NatureCity Podcast for weekly episodes on natural health, science-backed supplements and wellness strategies that actually work. ABOUT NATURECITY NatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served, NatureCity is committed to quality, honesty and results. https://www.naturecity.com/ #NatureCity #CalmingEnergy #StressRelief #NaturalFocus #TrueMind | |||
| Magnesium Bisglycinate Chelate vs. Glycinate: What You’re Not Being Told | 03 avr. 2026 | 00:10:28 | |
Is your magnesium supplement actually what it claims to be? Carl Pradelli, CEO and Co-Founder of NatureCity, breaks down the critical difference between magnesium glycinate and magnesium bisglycinate chelate so you stop wasting money on supplements that may look good on the label but don’t deliver.
Subscribe for weekly supplement truths.
WHAT YOU’LL LEARN ✓ Why magnesium glycinate and magnesium bisglycinate chelate are NOT always the same thing ✓ How some brands blend magnesium oxide with glycine and still call it magnesium glycinate ✓ The 10% elemental magnesium rule that exposes low-quality supplements instantly ✓ Why Albion is considered the gold standard for chelated mineral sourcing ✓ How NatureCity-’s TrueMagnesium delivers 200mg of pure bisglycinate chelate in a drink powder
Magnesium is involved in over 300 processes in your body, from sleep and muscle function to energy, mood, and heart health. Most people are not getting enough magnesium from diet alone, which makes supplementation important. But here is the problem: not all magnesium supplements are created equal, and the labels could be misleading.
In this episode, Carl Pradelli explains the details behind magnesium bisglycinate chelate, a fully reacted form of magnesium bound to two glycine molecules. This form has been shown to be absorbed up to 3x to 4x times better than other magnesium options with significantly fewer digestive issues. This makes it one of the most desirable forms of magnesium for supplements.
Usually, magnesium bisglycinate chelate is labeled as such, but technically it could be also labeled as “magnesium glycinate.” However, here is the important part you need to know: not all magnesium glycinate is magnesium bisglycinate chelate.
Carl exposes how some supplement companies use partially reacted magnesium or blend magnesium oxide with glycine, and label it as magnesium glycinate - but this is not a true and pure magnesium bisglycinate chelate and will not perform like it in the body.
Carl walks through how to read a supplement label to spot the difference, including the 10% elemental magnesium benchmark. You’ll also see why high milligram-per-capsule magnesium claims are a red flag, and why Albion’s patented chelation process matters.
He also explains why NatureCity chose a raspberry-flavored drink powder format for TrueMagnesium to deliver a full 200mg dose of pure Albion magnesium bisglycinate chelate without requiring a handful of capsules.
NatureCity was founded over 20 years ago by Carl Pradelli and his wife Beth with a mission to deliver transparent, science-backed natural health supplements. Since then, NatureCity has served over 500,000 customers and remains committed to quality, honesty, and results.
TIMESTAMPS 0:00 — Why your magnesium supplement might not be working 0:38 — Why magnesium matters for sleep, energy, and overall health 1:20 — The confusion: glycinate vs. bisglycinate 2:05 — The key difference that actually matters 2:50 — What makes this form easier for your body to absorb 4:35 — The problem with most magnesium supplements 5:45 — Why some “glycinate” isn’t really glycinate 6:25 — The truth about “buffered” magnesium 7:10 — How to read a magnesium label the right way 8:05 — How to spot a low-quality supplement fast 9:05 — Recap: how to choose the right magnesium
Learn more about TrueMagnesium and NatureCity’s full supplement line at naturecity.com ABOUT NATURECITY NatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served, NatureCity is committed to quality, honesty, and results. #NatureCity #MagnesiumSupplement #MagnesiumBisglycinate #NaturalHealth | |||
| Biotin and Silica for Hair: New Study Shows Real Results | 20 mars 2026 | 00:09:58 | |
Hair thinning and excess shedding are common concerns — but can targeted nutrition help? In this episode of the NatureCity Podcast, Carl Pradelli breaks down a new placebo-controlled study evaluating plant-based biotin (RGen-Bio®) and silica (RGgen-Si™), and their impact on hair loss, hair growth, thickness, and overall appearance. Plus, you’ll see how these nutrients helped skin and nails too. You’ll learn how these nutrients support the hair growth cycle, why mitochondrial activity matters at the follicle level, and what the research actually showed after 90 days. Watch now to see what the science says. → Learn more about TrueNuGrow+ at https://www.naturecity.com/products/truenugrow
WHAT YOU'LL LEARN IN THIS EPISODE
✓ How a 90-day placebo-controlled trial measured real improvements in hair loss, thickness, density, and shedding
✓ The three phases of hair growth and what causes follicles to shift into the shedding phase
✓ The role of biotin in keratin production and follicle metabolism
✓ How silica supports collagen formation to anchor hair follicles and strengthen the hair shaft
✓ Bonus benefits: skin elasticity, hydration, wrinkle reduction, and smoother nails from the same nutrients
EPISODE BREAKDOWN A newly published randomized, double-blind, placebo-controlled study tested plant-based biotin (from RGen-Bio, extracted from the sesbania plant) and silica (from RGen-Si, extracted from bamboo shoots) on 97 men and women aged 20 to 60. All participants reported hair appearance concerns at baseline.
Over 90 days, participants taking 2.5 mg of biotin daily — or the biotin combined with 40mg of silica — experienced significant reductions in daily hair fall (normal hair loss), meaningful increases in hair thickness and density measured by advanced scalp imaging, and faster hair growth rates compared to placebo.
Carl explains how these results connect to the three-phase hair growth cycle: anagen (active growth), catagen (transition), and telogen (resting and shedding). When nutritional deficiencies, stress, or aging push more follicles into the telogen phase, shedding accelerates. Biotin supports keratin production and cellular energy metabolism in follicles, while silica supports the collagen and connective tissue that anchor hair in the scalp.
Researchers also observed improvements in skin elasticity, hydration, crow’s feet wrinkle appearance, and fingernail smoothness — because hair, skin, and nails share the same structural proteins and may all benefit from biotin and silica support.
NatureCity’s TrueNuGrow+ formula uses these exact plant-based biotin and silica sources at the same doses proven effective in this study, plus additional research-backed nutrients for comprehensive hair and skin support. SUBSCRIBE to the NatureCity Podcast so you never miss an episode on evidence-based nutrition and supplement science. 🌿 RESOURCES TrueNuGrow+ Hair & Skin Formula: [INSERT LINK] NatureCity Website: https://www.naturecity.com ABOUT NATURECITY Founded over 20 years ago by Carl and Beth Pradelli, NatureCity has served more than 500,000 Americans with premium, research-backed supplements. Every product is built on four ironclad commitments to quality, transparency, potency, and purity. Follow NatureCity: Instagram: https://www.instagram.com/NatureCitySupplements/ Facebook: https://www.facebook.com/naturecitysupplements #NatureCity #BiotinForHair #HairGrowthSupplements #PlantBasedBiotin #HealthyHairScience | |||
| Beyond Heart Health: Ubiquinol Supports Brain, Muscle & Bone Health Too | 12 mars 2026 | 00:07:34 | |
Your body runs on cellular energy, and your cells constantly need to produce new energy. In the last episode, we explored how ubiquinol, the active form of CoQ10, supports heart health by fueling the massive energy demands of the heart. But the heart is not the only organ that relies heavily on cellular energy. In this episode of the NatureCity Podcast, CEO and co-founder Carl Pradelli expands the conversation beyond cardiovascular health and explains how ubiquinol can also support healthy function of the brain, skeletal muscle, and bone tissues. Carl explains how ubiquinol helps mitochondria produce ATP, the cellular energy your body runs on, while also helping protect cells from oxidative stress. Both processes become increasingly important as we age. Subscribe to the NatureCity Podcast for weekly science-backed supplement insights. WHAT YOU'LL LEARN ✅ Why the brain uses about 20 percent of the body’s total energy ✅ How mitochondrial decline contributes to fatigue, muscle loss, and cognitive aging ✅ The connection between cellular energy and healthy brain function ✅ How CoQ10 may support muscle performance and exercise recovery ✅ Why researchers are exploring ubiquinol’s role in bone metabolism and bone health ✅ How supporting mitochondrial health may promote whole body resilience as we age EPISODE SUMMARY Most people associate CoQ10 and ubiquinol with heart health, and for good reason. In our previous episode, we discussed how the heart beats about 100,000 times per day and depends heavily on mitochondrial energy production to keep working nonstop. But the heart is only one of several tissues in the body that rely on efficient cellular energy production. In this episode, Carl expands the conversation to three additional areas where mitochondrial energy plays a critical role: the brain, skeletal muscle, and bone. Although the brain represents only about 2 percent of body weight, it consumes roughly 20 percent of the body’s energy supply. Every thought, memory, and nerve signal depends on ATP produced inside brain cells. Research suggests that maintaining mitochondrial efficiency may be one of the most important strategies for supporting cognitive health as we age. Skeletal muscle is another tissue that relies heavily on energy production. Muscle cells require ATP for every contraction, whether you are walking, exercising, or simply standing. Studies suggest CoQ10 supplementation may help support muscle energy production, reduce exercise related fatigue, and promote recovery. Emerging research also suggests ubiquinol may support healthy bone metabolism. Bone is constantly being remodeled through the balance of bone-forming osteoblasts and bone-breaking osteoclasts. Oxidative stress and mitochondrial dysfunction may influence this balance, making cellular energy an important factor in maintaining healthy bone density. Across all these systems, a clear pattern emerges. The brain, muscles, bones, and heart all depend on efficient cellular energy production and protection from oxidative stress. Ubiquinol supports both of these processes by helping mitochondria produce energy while also acting as a powerful antioxidant. TIMESTAMPS 00:00 Introduction 00:47 Recap of last episode on ubiquinol and heart health 01:27 Why cellular energy matters beyond the heart 01:45 The brain’s massive energy demand 02:30 How ubiquinol may support brain health 03:21 Skeletal muscle and mitochondrial energy 04:00 CoQ10 research on exercise and recovery 04:26 Why muscle health supports independence as we age 04:44 Ubiquinol and emerging research on bone health 05:06 Osteoblasts vs osteoclasts and how bone remodeling works 06:05 The bigger picture of mitochondria and healthy aging 07:06 How TrueCoQ10 supports cellular energy production 07:22 NatureCity’s advanced ubiquinol delivery system 07:37 Final thoughts and episode wrap-up SUBSCRIBE to the Nature City Podcast for science-backed supplement education from a company that's served over 500,000 Americans in 20+ years. LINKS AND RESOURCES Learn more about True CoQ10: https://www.naturecity.com/products/true-coq10-100mg?_pos=2&_sid=6aff9fd22&_ss=r Browse all Nature City supplements: https://www.naturecity.com/ Watch more Nature City Podcast episodes: https://www.youtube.com/playlist?list=PLRwO7b_fPoq6knehENg5yRD3O5IuoMBmk ABOUT THE HOST Carl Pradelli is the CEO and co-founder of Nature City, a supplement company he started over 20 years ago with his wife Beth. Nature City has served over 500,000 Americans with science-backed, quality-first nutritional supplements. #NatureCityPodcast #Ubiquinol #HealthyAging #Mitochondria #CoQ10 | |||
| Your Heart Stores Only 10 Seconds of Energy — Why Ubiquinol Matters | 26 févr. 2026 | 00:11:10 | |
Your heart beats 100,000 times a day and pumps up to 10 tons of blood — but most people never think about the energy it takes to keep it going.
In this American Heart Month episode, NatureCity CEO and co-founder Carl Pradelli breaks down the critical connection between heart health and cellular energy — and explains why ubiquinol, the active form of CoQ10, may be the most overlooked supplement for long-term cardiovascular support.
Subscribe to the NatureCity Podcast for weekly science-backed supplement insights.
WHAT YOU'LL LEARN
✅ Why your heart needs more energy than any other organ — and what happens when it doesn't get enough
✅ The 4 ways ubiquinol supports heart and cardiovascular health
✅ Why CoQ10 levels drop by 40% between ages 20 and 40 — and keep declining
✅ The difference between ubiquinone and ubiquinol (and why the form you take matters)
✅ How the formulation used in NatureCity's TrueCoQ10 supplement showed 4.3x greater absorption in a double-blind study
EPISODE SUMMARY
Most conversations about heart health focus on cholesterol, blood pressure, and exercise – all very important . But your heart is also the most energy-demanding organ in your body. A single heart muscle cell contains thousands of mitochondria working around the clock to produce ATP — and your heart stores only about 10 seconds' worth at any given moment. That constant demand makes the heart uniquely dependent on efficient energy production.
Ubiquinol, the active antioxidant form of CoQ10, plays a direct role in the electron transport chain that generates ATP. It also protects mitochondrial membranes from the free radicals that energy production creates as a byproduct. Unfortunately, natural CoQ10 levels peak around age 20 and decline steadily from there — dropping approximately 40% in heart cells by age 40.
Carl walks through four specific ways ubiquinol supports heart health: fueling the heart's ATP production and supporting healthy ejection fraction, protecting mitochondria from oxidative stress, shielding LDL cholesterol from oxidation (which research suggests ubiquinol may do even more effectively than vitamin E), and supporting nitric oxide production for healthy blood flow and vascular flexibility.
The episode also covers why the form and formulation of CoQ10 matters. Carl explains the difference between ubiquinone and ubiquinol, why conversion efficiency declines with age, and how NatureCity's TrueCoQ10 uses Kaneka Ubiquinol with an advanced delivery system that demonstrated 4.3 times greater blood plasma levels in a published double-blind study.
Scroll down to the timestamps to jump straight to any of the four heart health benefits.
TIMESTAMPS
00:00 Introduction and American Heart Month 00:31 The heart's extraordinary energy demands 01:23 Mitochondria, ATP, and why ubiquinol matters 02:36 CoQ10 levels decline with age 03:33 CoQ10 basics: ubiquinone vs. ubiquinol 04:41 Benefit 1: Fueling heart energy and ejection fraction 06:04 Benefit 2: Protecting mitochondria from oxidative stress 07:34 Benefit 3: Shielding LDL from oxidation 09:08 Benefit 4: Nitric oxide and healthy blood flow 11:04 Why supplementing after age 20 makes sense 11:34 Why the form of CoQ10 matters 12:09 Kaneka Ubiquinol and quality sourcing 12:29 TrueCoQ10's advanced delivery system 13:46 The 4.3x absorption study 14:46 Dosage recommendations 15:09 Summary: ubiquinol at the intersection of energy, oxidative balance, and blood flow
SUBSCRIBE to the Nature City Podcast for science-backed supplement education from a company that's served over 500,000 Americans in 20+ years.
LINKS AND RESOURCES
Learn more about True CoQ10: https://www.naturecity.com/products/true-coq10-100mg?_pos=2&_sid=a66fd410e&_ss=r
Browse all Nature City supplements: https://www.naturecity.com/
Watch more Nature City Podcast episodes: https://www.youtube.com/playlist?list=PLRwO7b_fPoq6knehENg5yRD3O5IuoMBmk
ABOUT THE HOST
Carl Pradelli is the CEO and co-founder of Nature City, a supplement company he started over 20 years ago with his wife Beth. Nature City has served over 500,000 Americans with science-backed, quality-first nutritional supplements.
#NatureCityPodcast #Ubiquinol #HeartHealth | |||
| Astaxanthin Update: Vision, Skin, Muscle Recovery & Emerging Brain Health Research | 12 févr. 2026 | 00:56:54 | |
In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli welcomes back Dr. Karen Hecht, Vice President of Science at AstaReal, along with Dr. Susan Hamrahi, who leads scientific communications. Astaxanthin has long been recognized as one of nature’s most powerful antioxidants — but since Carl and Dr. Hecht’s original deep dive in Episode 9, a wave of new human research has expanded our understanding of how this unique carotenoid supports vision, skin health, muscle endurance and recovery, immune resilience, and even emerging areas of cognitive performance. In this updated conversation, the group breaks down why astaxanthin is structurally different from other antioxidants, how it uniquely protects cells without becoming pro-oxidant, and why its ability to support mitochondrial function makes it relevant for both everyday energy and athletic performance. They also explore why AstaReal® natural astaxanthin, derived from Haematococcus pluvialis algae, has become the gold standard for research-backed supplementation — with over 85 human scientific studies supporting its safety, bioavailability, and effectiveness. If you’re looking for a science-driven update on one of the most versatile nutrients in healthy aging — and want practical guidance on dosing, benefits, and who may benefit most — this episode delivers a comprehensive, evidence-based overview. WHAT YOU'LL LEARN
REFERENCES The Lopresti Study: https://pubmed.ncbi.nlm.nih.gov/38892705/ The ISSN Position Stand on Antioxidants: https://pubmed.ncbi.nlm.nih.gov/41701327/ SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical healthy aging insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore NatureCity supplements at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #Astaxanthin #AstaReal #VisionHealth #SkinHealth #MuscleRecovery #MitochondrialHealth #HealthyAging #SupplementScience | |||
| Omega-3s, Brain Health, and Why Blood Levels Matter | 29 janv. 2026 | 00:08:47 | |
In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli breaks down a newly published study that takes a deeper — and more impactful — look at omega-3s and brain health. Rather than relying on food questionnaires or supplement surveys, this new research measured omega-3 blood levels, offering a clearer picture of how EPA and DHA status relates to the earliest biological stages of age-related cognitive decline. The findings reinforce an idea Carl has emphasized before: when it comes to omega-3s, long-term blood levels matter far more than short-term intake. Carl revisits key insights from Episode 115 on omega-3s and brain health, then explains what makes this study different — including its focus on the Omega-3 Index as a predictor of cognitive aging risk. The research showed that individuals with an Omega-3 Index above 8% had significantly better brain aging outcomes, while most people in Western populations fall far below that range. The episode also explores why simply “taking fish oil” doesn’t guarantee results. Carl explains the importance of consistent intake, proper dosing, balanced EPA and DHA ratios, and — critically — absorption and bioavailability. He breaks down why some people see meaningful benefits from omega-3s while others don’t, and how advanced delivery systems can dramatically impact results. If you’re interested in protecting brain health decades before symptoms appear — and want practical, measurable strategies instead of guesswork — this episode offers clear guidance grounded in human research. WHAT YOU’LL LEARN
SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical healthy aging insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore NatureCity supplements at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #Omega3 #BrainHealth #CognitiveAging #HealthyAging #Omega3Index #EPA #DHA #LongevityScience #SupplementScience #HealthSpan | |||
| New Science: Resveratrol Can Help Skin Appearance | 22 janv. 2026 | 00:08:38 | |
In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli breaks down a newly published human study on resveratrol — and why its findings go beyond skin-deep benefits. Resveratrol has long been discussed for its role in healthy aging, heart health, and longevity. But this new research shifts the spotlight to something many people notice first as they age: visible changes in skin firmness, elasticity, and wrinkles. What makes this study especially noteworthy is that it didn’t use just any resveratrol — it used Veri-te® resveratrol, the fermented form found in NatureCity’s TrueResveratrol. Carl walks through exactly what the study showed, who participated, the surprisingly low dose that was used, and why this specific form of resveratrol appears to work differently than many high-dose products on the market. He also explains why improvements in skin health often reflect broader biological support — including antioxidant protection, a healthy inflammation response, mitochondrial function, and cellular repair. Beyond skin aging, the episode explores how resveratrol — particularly the low dose Veri-te® — has also been studied for bone health, cardiovascular support, metabolic function, and brain health, reinforcing its role as a foundational, multi-system aging nutrient rather than a cosmetic-only supplement. If you’re curious about resveratrol but want evidence-based guidance — not hype or mega-dose guesswork — this episode offers clarity, context, and practical takeaways grounded in human research. WHAT YOU’LL LEARN
SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical healthy aging insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore NatureCity supplements at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #Resveratrol #HealthyAging #SkinHealth #BoneHealth #LongevityScience #AntiAgingResearch #SupplementScience #HealthSpan #VeriteResveratrol | |||
| Do You Really Need Expensive Longevity Supplements? | 16 janv. 2026 | 00:10:42 | |
In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a step back from the hype surrounding cutting-edge longevity supplements to ask a more practical — and important — question: Do you really need expensive, trendy longevity products to support healthy aging? With longevity now dominating wellness headlines, many supplements promise to slow aging, lengthen telomeres, boost NAD+, or activate autophagy — often at a steep monthly cost and with limited long-term human research. Carl explains why longevity isn’t driven by a single “magic molecule,” but by a network of systems including a healthy inflammation response, oxidative stress protection, cardiovascular health, immune system regulation, brain function, and cellular integrity. In this episode, Carl breaks down how well-established nutrients — backed by decades of human research — already support many of the same biological pathways targeted by newer longevity compounds. He highlights three foundational supplements that almost everyone should prioritize first for both health span and longevity:
Carl explains how these nutrients support the same health systems targeted by newer longevity compounds, and even mitochondrial function and telomere integrity too — all without the uncertainty and cost of newer longevity “stacks.” You’ll also learn why optimizing the fundamentals can deliver powerful aging benefits today, not just theoretical lifespan gains decades from now. If you’re curious about longevity but want science-backed, realistic guidance before spending hundreds of dollars a month on supplements, this episode is for you. WHAT YOU’LL LEARN
SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical longevity insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore NatureCity supplements at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #Longevity #HealthyAging #VitaminD #Omega3 #Tocotrienols #Telomeres #AntiAgingScience #HealthSpan #SupplementScience | |||
| Do Coffee & Tea Affect Bone Health? | 09 janv. 2026 | 00:07:55 | |
Is your daily coffee helping you… or quietly harming your bones? And could tea actually strengthen them? In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli revisits a popular question from a past episode: Is caffeine bad for bone health? This time, he breaks down new research published in late 2025 that followed nearly 10,000 women over age 65 for a decade — revealing some surprising differences between coffee and tea when it comes to bone mineral density. Carl explains why moderate coffee intake is usually safe, when it can become a concern (especially for postmenopausal women), and why tea — particularly green and white tea — may actually support stronger bones thanks to powerful polyphenols. He also shares practical, realistic strategies for protecting bone health without giving up your morning cup of coffee. Finally, Carl explains why bone health requires far more than calcium alone, and how NatureCity’s Tru Osteo® and Tru Osteo Plus® formulas are designed to support not just slowing bone loss — but potentially improving bone density over time. If you care about aging well, staying active, and keeping your bones strong for the long haul, this episode is a must-listen. WHAT YOU’LL LEARN
SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical wellness insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore Tru Osteo® and Tru Osteo Plus® at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #BoneHealth #CoffeeAndBones #TeaBenefits #HealthyAging #Calcium #VitaminD #VitaminK2 #OsteoporosisPrevention | |||
| The PEA Advantage: Joint Comfort, Faster Recovery, Sleep & Stress Support | 19 déc. 2025 | 00:08:06 | |
Joint discomfort, sore muscles, restless nights, and being overwhelmed by daily stress seem like separate challenges — but did you know your body naturally makes a nutrient that offers support for all of them? In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a deep dive into PEA (palmitoylethanolamide)—a naturally occurring fatty compound your body uses to manage discomfort, stress, and support a healthy inflammation response. Carl explains how PEA levels tend to decline with age (when we need PEA most), why most PEA supplements fall short, and how the best studied form of PEA, called Levagen+, overcomes absorption challenges and delivers results using the novel LipiSperse delivery technology. With over 14 published human studies, Levagen+ has been shown to support joint comfort, flexibility, muscle recovery, sleep quality, cognitive performance, immune health, and more. This is why we made Levagen+ a cornerstone ingredient in TrueJoint FLX, NatureCity’s premium joint formula, which was designed to help you start feeling better within days — and help keep you mobile and active with better joint function over time. If you want to support joint health, recover faster, sleep better, and support long-term resilience as you age, this episode is a must-listen. WHAT YOU’LL LEARN What PEA is and how your body naturally uses it PEA production declines with age — so supplementation makes sense Why Levagen®+ is the best PEA for supplements
TIMESTAMPS 0:00 – Welcome & why PEA deserves attention 1:04 – What PEA is and where it comes from 1:51 – PEA levels decline with age 2:15 – The absorption problem with standard PEA supplements 2:38 – Why Levagen®+ is different 3:02 – LipiSperse® technology & absorption benefits 3:30 – Joint comfort, stiffness, and flexibility research 4:40 – Muscle recovery, soreness, and performance support 5:42 – Sleep quality, stress balance, and nervous system support 6:15 – Cognition, BDNF, and mental alertness findings 6:58 – Heart rate variability support & stress resilience 7:21 – Emerging research: menstrual comfort, gut & metabolic health 8:04 – Final thoughts & where to learn more SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical wellness insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and more 💬 Comment below with your biggest takeaway from this episode Explore the full TrueJoint FLX formula at https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #PEA #LevagenPlus #JointHealth #MuscleRecovery #SleepSupport #StressSupport | |||
| Keeps Your Skin Hydrated – With Less Hair Loss Too | 11 déc. 2025 | 00:08:26 | |
Skin creams and serums can only do so much to keep your skin and hair looking their best. Support starts from within your body. This is especially true when it comes to reinforcing your skin’s moisture barrier and protecting hair cuticles with ceramides. In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli introduces Ceramosides®—a plant-based, gluten-free ceramide supplement that’s changing the way we support skin and hair health. Carl explains how Ceramosides® works from within to help increase skin hydration and elasticity, while reducing the appearance of fine lines and wrinkles. More recently, Ceramosides® has also been shown it can help create a healthier scalp environment that supports stronger, fuller-looking hair, and reduces normal hair loss. Backed by five published scientific studies and a new consumer trial with 95 men, this episode is a must-listen if you’re interested in aging more gracefully, reducing hair shedding, or optimizing your skincare routine. You'll also find out why Ceramosides® is uniquely effective compared to other ceramide ingredients - and how it perfectly complements other researched ingredients like keratin and collagen in NatureCity’s new TrueNuGrow+ Hair & Skin Formula. If you want to keep your skin and hair looking its best, or you’re just curious about how science-backed supplement ingredients can boost your natural glow—this episode is for you. WHAT YOU’LL LEARN
SUBSCRIBE & CONNECT Don't miss future episodes packed with supplement science and real wellness solutions. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and more 💬 Let us know your favorite part of this episode in the comments! Explore the full True NewGrow Plus formula at https://www.naturecity.com WELCOME TO THE NATURECITY YOUTUBE CHANNEL Here you'll find expert-led insights into natural supplements and holistic health. Hosted by Carl Pradelli, NatureCity’s co-founder, our videos blend trusted science with practical advice to help you make informed wellness decisions. Each episode dives deep into key ingredients, emerging research, and proven supplement stacks designed to support energy, beauty, digestion, and longevity. FOLLOW US
#NatureCityPodcast #Ceramides #HairSupplements #SkinHealth #Ceramosides | |||
| Over 50% Of Berberine Supplements Tested Failed | 21 nov. 2025 | 00:08:30 | |
Fraudulent products are a real concern for supplement buyers. The latest example of this was revealed in lab testing of top selling berberine supplements purchased on Amazon. The results were pretty shocking with the majority of supplements seemingly containing less than 10% of the berberine claimed on the product label – with a couple containing none at all. In this eye-opening episode of the NatureCity Podcast, host and supplement industry veteran Carl Pradelli breaks down the findings and why if a supplement price seems too good to be true, it probably is. You’ll also find out why solely relying on Amazon star ratings and badges may not protect you from purchasing a fraudulent supplement. Carl also dives into why berberine has become a target for fraudulent supplement makers: it's growing in popularity for supporting blood sugar, metabolic health, and weight management, but a high dose is required for results (which make it more costly to produce). This has opened the door for bad actors to cut corners. Carl also outlines the biological role of berberine, including how it supports AMPK enzyme activity, blood sugar metabolism, and insulin function. He also discusses GlucoVantage, a newer form of berberine (dihydroberberine) that offers superior absorption and far fewer stomach and gastrointestinal issues—making it a game-changer for anyone interested in the benefits of berberine. This episode doesn’t just warn you—it equips you. Learn how to spot quality supplements, why price matters, and how combining berberine with strength training can improve body composition and reduce fat storage. If you’re looking to optimize your supplement stack or protect your health investment, this episode is a must-listen. Don’t risk your health or waste your money. Subscribe for honest supplement insights and insider tips that protect your wellness journey. WHAT YOU’LL LEARN
Subscribe for weekly supplement science breakdowns and wellness tips. What’s your biggest takeaway from this episode? Let us know in the comments. Shop NatureCity’s TrueBerberine at https://www.naturecity.com WELCOME TO THE NATURECITY YOUTUBE CHANNEL On the NatureCity YouTube Channel, you’ll find expert-led insights into natural supplements and digestive health. With over 20 years of experience, Carl creates videos packed with practical, science-backed information to help you make informed health choices. Our channel provides in-depth overviews of our top supplements, like the TrueDYB formula. We break down how each ingredient supports digestive health, immunity, and overall wellness, so you can see exactly how our products are designed to maximize benefits. If you’re curious about what makes these supplements effective, we’ll guide you through the science and thought behind each one. Our videos cover essential digestive health topics, such as managing leaky gut and boosting nutrient absorption. You’ll find straightforward tips to support your gut health and better understand the role of supplements in your daily wellness. Each video simplifies complex nutritional concepts, explaining how popular ingredients interact to support your body’s natural functions. Subscribers also gain access to honest Q&A sessions and product reviews. If you have questions about a specific supplement or a health concern, we provide clear, direct answers to help you choose products that meet your needs. With real testimonials and our honest approach, you’ll feel confident about the supplements you choose. Beyond supplements, we share guidance for a balanced, holistic lifestyle. Our wellness videos offer actionable tips on diet, lifestyle adjustments, and strategies for boosting energy and longevity. We believe health goes beyond products, so we’re here to support your journey to better well-being. By subscribing to our channel, you’ll join a community that values transparency, quality, and above all, your health. Let NatureCity be your trusted source for reliable, science-based wellness information, helping you take meaningful steps toward a healthier life. FOLLOW NATURECITY ON SOCIAL MEDIA Instagram: https://www.instagram.com/NatureCitySupplements/ Facebook: https://www.facebook.com/naturecitysupplements #NatureCityPodcast #SupplementScam #BerberineBenefits Keywords: berberine supplement fraud, GlucoVantage, blood sugar support, supplement quality control, Amazon supplement reviews | |||
| New Melatonin Study Raises Red Flags: What Does It Mean? | 14 nov. 2025 | 00:10:49 | |
A new study sponsored by the American Heart Association links long-term melatonin use to increased risk of heart failure and early death—but is the data trustworthy? What does this mean for supplement users? In this episode, Carl Pradelli breaks down the controversial melatonin study making headlines and the potential issues with how the study was conducted. Carl also shares his concerns with taking melatonin regularly or taking excessive amounts. He also reveals the spice that can be a better option as a supplement because it supports your body’s natural melatonin production process and has been shown to help increase sleep quality and mood upon awakening. Subscribe to stay ahead of the health curve. What You’ll Learn:
Subscribe for weekly natural health insights and supplement strategies. What do you think about melatonin—have you had a positive or negative experience? Drop your thoughts in the comments 👇 Explore TrueZs and support natural melatonin production: https://www.naturecity.com #NatureCityPodcast #MelatoninRisks #SleepSupplements | |||
| The Benefits of DE111: The Spore-Forming Probiotic That Delivers | 07 nov. 2025 | 00:07:28 | |
In this episode of The NatureCity Podcast, host Carl Pradelli, CEO and co-founder of NatureCity, explores the benefits of one of the best probiotic strain options available for supplements. It’s a strain of Bacillus subtilis called DE111®. Carl explains how your gut is estimated to contain more than 100 trillion bacteria, which is why supplementing with a diverse group of probiotic strains may help you maintain a healthy balance of beneficial gut bacteria – which is believed to be foundational to good health. You’ll hear how DE111 stands apart from the more common Lactobacillus and Bifidobacterium probiotic strains (which are also important) by forming protective spores that ensure survival during manufacturing, storage, and digestion. DE111 has been the subject of much research, and Carl also details some of the key benefits highlighted in these scientific studies. These benefits go beyond the expected digestive and immune health support. This episode is a must-listen for anyone interested in practical, science-based ways to improve digestion and strengthen the gut microbiome and wellness naturally. What You’ll Learn in This Episode
Links & Resources Learn more about True DYB (“Digest Your Best”) and True Life PB: Subscribe for weekly science-backed gut health insights: YouTube: NatureCity Channel What was your biggest takeaway from this episode? Share your thoughts in the comments below. About Carl Pradelli Carl Pradelli is the co-founder and CEO of NatureCity, a trusted supplement company serving over 500,000 Americans for more than two decades. Through The Nature City Podcast, Carl shares science-driven insights on nutrition, gut health, and the pursuit of natural wellness. Calls to Action
#NatureCityPodcast #GutHealthTips #ProbioticScience | |||
| Supplement Shopping Tip #3 – Understanding the Brand Owners’ Motivations | 24 oct. 2025 | 00:07:31 | |
Finding the right supplements and a brand you can trust can feel overwhelming. How do you know which ones truly care about your health? In this episode of the NatureCity Podcast, host and CEO Carl Pradelli shares his 3rd essential tip for buying dietary supplements: know who owns and runs the brand - and why the brand exists. Carl explains why transparency, integrity, and experience matter more than ever in a marketplace filled with counterfeit and fraudulent products, subpar formulas and low-quality imitators. You’ll learn how to spot red flags, avoid wasted money, and confidently choose quality supplements that help you. Whether you’re new to natural health or a long-time supplement user, this insider advice from a 24-year industry veteran helps you become a more informed and empowered consumer. Subscribe for weekly wellness tips. WHAT YOU’LL LEARN: • Why the people behind a supplement company matter. • Brands with nothing to hide, hide nothing, and share ingredient sources, manufacturing details, and consumer friendly policies. • Why it can take years in the industry to figure out who in the supply chain can be trusted, and deliver for you • How mergers, investor buyouts, and rebranding can change product quality almost overnight. • What the length of a money back guarantee reveals about a company’s confidence in its products. Don’t miss the earlier deep-dive: The #1 Tip for Choosing Quality Supplements: https://www.youtube.com/watch?v=lpXEJXxtnvU Why the supplement manufacturer matters more than the brand: https://www.youtube.com/watch?v=fSRqjG-M8FY 📣 CALL TO ACTION Visit https://www.naturecity.com to explore trusted, high-quality supplements backed by over 20 years of experience. Comment below with your biggest takeaway from Carl’s supplement-buying tips! #NatureCity #SupplementShoppingTips #DietarySupplements #WellnessPodcast #NaturalHealth #SupplementAdvice #HealthyLiving | |||
| New Science: OptiMSM Boosts Muscle Recovery | 10 oct. 2025 | 00:07:51 | |
Staying active is key to good health. But it’s hard to do if your muscles don’t recover quickly and soreness lingers. New scientific evidence shows how OptiMSM can help your body recover faster. In this episode of the NatureCity Podcast, host and CEO Carl Pradelli dives into the latest research with OptiMSM, which is a premium form of MSM (methylsulfonylmethane). Find out how this sulfur-rich compound helps your body bounce back faster, reduce oxidative stress, and support healthy post-exercise immune and inflammation responses. Whether you're a runner, gardener, weekend warrior or just trying to stay fit, this natural recovery aid can help your feel better today and get you ready for tomorrow. Even better, there are many other ways OptiMSM can help you, especially for hair, skin and joint health because it plays a vital role in supporting collagen, keratin, and connective tissue throughout the body. Tune in to discover how OptiMSM may help you. Subscribe for weekly wellness tips. ✅ WHAT YOU’LL LEARN:
Don’t miss the earlier deep-dive: Episode 110 – OptiMSM for Hair, Skin & Joints ⏱️ TIMESTAMPS:0:00 Welcome + Why Recovery Matters More With Age 1:40 What Is OptiMSM? The Sulfur Containing Compound Behind Faster Recovery 3:00 New Study Breakdown – OptiMSM vs. Placebo in Marathon Runners 4:55 Biomarker Improvements – How MSM Reduces Oxidative Stress and Muscle Damage 6:00 Surprising Results at Lower Doses (500–1000mg) 7:10 OptiMSM Can Work for Everyday Movement, Not Just Athletes 8:00 Recap 📣 CALL TO ACTIONVisit https://www.naturecity.com to explore OptiMSM. | |||
| More Evidence of Tocotrienol Brain Benefits – Why Your Vitamin E Supplement May Be Incomplete | 26 sept. 2025 | 00:08:02 | |
You’ve heard of vitamin E—but have you heard of tocotrienols? These powerful compounds are also part of the vitamin E family, but hard to get from the food we eat, and are usually missing from regular vitamin E supplements. Research is finding tocotrienols may be more beneficial than alpha-tocopherol (the more well-known member of the vitamin E family) for certain key areas of our health – including aspects of brain, heart, and liver function. In this episode of the NatureCity Podcast, host and CEO Carl Pradelli highlights key findings from two newly published studies showing the potential of tocotrienols protecting brain cells supporting memory and focus, and promoting healthy brain aging. Carl explains the crucial difference between tocopherols and tocotrienols, and why the latter may be up to 60x better at fighting oxidative stress. This episode is a must-listen if you want to stay mentally sharp, focused, and vibrant through the years. Discover why NatureCity’s TrueE formula includes all four tocotrienols along with alpha-tocopherol — all naturally sources, to give your body the best of what vitamin E has to offer. Tocotrienols may be the brain's best-kept secret. Learn how to unlock their power—subscribe now! What You’ll Learn:
💡 Enjoy this episode? Subscribe and leave a review on YouTube or your favorite podcast app. 🔎 Learn more about TrueE and tocotrienols at https://www.naturecity.com 📧 Share this episode with a friend who’s focused on healthy aging! #BrainHealth #Tocotrienols #VitaminESupplement #CognitiveSupport #HealthyAging | |||
| Why Omega-3s Matter for Brain Health | 11 sept. 2025 | 00:09:30 | |
In this week’s episode of the NatureCity Podcast, we explore the importance of the omega-3 fatty acids DHA and EPA for brain health and cognitive function – particularly as we age. NatureCity co-founder and CEO, Carl Pradelli, covers what DHA and EPA actually do for your brain and why Americans, on average, only get about 10% of the ideal amount of these omega-3s daily from diet. Taking a supplement is a smart way to help bridge this shortfall. Carl explains what you need to look for to effectively boost your omega-3 levels and get the most for your money. 👉 Don’t forget to like, comment, and subscribe to stay connected with future episodes! What You’ll Learn in This Episode:
Follow NatureCity on Social Media | |||
| Tart Cherry: The Muscle Recovery Secret of World-Class Athletes | 04 sept. 2025 | 00:09:05 | |
Why were many elite Tour de France cyclists drinking tart cherry juice during this grueling event? In this episode of the NatureCity Podcast, host Carl Pradelli explores what makes these cherries unique – and how they can aid joint and muscle recovery, and support performance during physical activity. Carl also details the premier form of tart cherry powder for supplements, called CherryPure®. You’ll hear how it can help support a healthy inflammation response, healthy uric acid levels, and other scientific findings. Whether you’re training, gardening, or just keeping up with a busy lifestyle, tart cherry can help you bounce back faster and feel your best. Our TrueBerry7 drink powder is formulated with CherryPure and six other high potency super fruit extracts, each offering unique benefits. You can find out more about TrueBerry7 here: https://www.naturecity.com/products/true-berry-7 👍 Like this video 💬 Comment with your experience using tart cherry 🔔 Subscribe to the channel so you never miss an episode of the NatureCity Podcast #TartCherry #MuscleRecovery #AthleteSupplements #TrueBerry7 #MontmorencyCherries #NatureCity #JointHealth #InflammationSupport #TourdeFrance | |||
| Sicilian Beauty Secret Offers Better Skin from Within | 26 août 2025 | 00:32:25 | |
In this episode of the NatureCity Podcast, host Carl Pradelli sits down with Jodi-Ann Blackwood from BIONAP USA to discuss the award winning Red Orange Complex® from Sicily, Italy. A blend of three Sicilian oranges, the Red Orange Complex® was recently named the 2025 NutraIngredients USA Ingredient of the Year in the Beauty from Within category, one of the hottest areas in the supplement world. Tune in to discover what makes this Sicilian blood orange extract so powerful and why this blend is considered a breakthrough for skin health, healthy aging, and overall wellness. Jodi-Ann and Carl break down the science, sustainability, and the incredible benefits of this antioxidant-rich ingredient. In This Episode, You’ll Learn:
Red Orange Complex® is featured in NatureCity’s own TrueNuGrow+ Hair & Skin Formula. 👉 If you’re passionate about natural wellness, healthy aging, and looking your best, this is an episode you don’t want to miss! 🔔 Subscribe & Stay Connected Don’t miss future episodes of the NatureCity Podcast! 🌐 Visit us at: NatureCity.com | |||
| Why Magnesium Matters for Your Health | 21 août 2025 | 00:11:56 | |
Magnesium is one of the most important minerals for your health—and one of the hardest to get enough of from diet alone. It’s estimated that 75% of adults in the U.S. fail to reach the Recommended Daily Allowance (RDA). This isn’t just unfortunate, it’s a true health concern. In this episode of the NatureCity Podcast, CEO and co-founder Carl Pradelli breaks down why magnesium diet shortfalls are such a widespread issue, why magnesium is so important, and signals from your body that your magnesium intake may be too low. You’ll also hear where some common forms of magnesium in supplements come up short and why Magnesium Bisglycinate Chelate is the gold standard. Carl also shares his personal experience (and his wife Beth’s story) about how this form of magnesium made a real difference in their lives. 👉 Whether you struggle with muscle cramps, sleep troubles, mood swings, or simply want to feel and function your best, this episode will help you understand how to get the magnesium your body truly needs. Key Takeaways:
Learn more about True Magnesium and True Zs: https://www.naturecity.com/ 👍 Like this video if you found it helpful 🔔 Subscribe & hit the bell so you never miss an episode 💬 Comment below: Have you tried supplementing with magnesium? What differences have you noticed? | |||
| How Your Probiotic Packaging Could Be Sabotaging Your Gut Health | 05 août 2025 | 00:08:59 | |
In this week’s episode of the NatureCity Podcast, Carl Pradelli—CEO and Co-founder of NatureCity— tackles an often overlooked, but surprisingly critical topic that could significantly impact the potency and effectiveness of your probiotics: how they’re packaged. Many users don’t realize that elements like moisture, heat, and air exposure are the enemies of live probiotic cells - and can drastically reduce the potency of your probiotic supplement before you’ve even opened the bottle. And it gets worse – each time you open the cap to take a capsule, moisture and air enter the bottle and further destroy probiotic CFU (number of probiotic cells) counts. Carl reveals the innovative new bottle that you should seek out for your probiotic supplements. Research studies have found it’s far superior to other common packaging options in protecting live probiotics – even after you begin taking the product. In this episode, you’ll find out:
If you’re relying on probiotics to support your immune system, digestive health, gut balance, or overall wellness, you don’t want to miss this episode. Learn more or shop TrueLife PB: https://www.naturecity.com 📩 Have questions? Contact us anytime at support@naturecity.com 🔔 Subscribe for more science-backed supplement insights every week 💬 Comment below: Have you ever thought about how your probiotic is packaged? | |||
| Not Just for Joints - The Overlooked Beauty Mineral | 29 juil. 2025 | 00:07:34 | |
In this episode, Carl Pradelli unpacks the surprising power of methylsulfonylmethane (MSM), especially in its ultra-pure OptiMSM® form. OptiMSM® provides sulfur, which may not sound exciting, but is essential for life and aging well. Traditionally, taken for joints, immune heath and antioxidant support, OptiMSM® might be your secret weapon for glowing skin and healthier looking hair. Often called the “beauty mineral,” MSM is needed to help the body produce collagen, elastin, keratin, and hyaluronic acid — essential compounds for youthful looking skin, resilient nails, and thicker, shinier hair. OptiMSM® helps your body inside and out. In addition to helping your appearance, it supports your body’s key antioxidant, glutathione, to help reduce oxidative stress, and can help you stay active with greater joint comfort and faster muscle recovery from activities. OptiMSM® is one of the cornerstone ingredients in NatureCity’s advanced TrueNuGrow+ hair and skin formula. What You’ll Discover:
Like what you heard? Subscribe on YouTube and drop a comment if you’ve tried OptiMSM® or TrueNuGrow+! 🔗 Learn more: https://naturecity.com 🎧 Listen on Spotify, Apple, or your favorite podcast platform 📩 Have questions? Reach out—we’d love to hear from you. | |||
| Flavonoids for Longevity: Extend Your Healthspan Naturally | 22 juil. 2025 | 00:07:27 | |
Is your diet unknowingly limiting your healthspan – and perhaps even your longevity? In this episode of the NatureCity Podcast, host and NatureCity CEO Carl Pradelli breaks down compelling new research from scientists in the UK and Australia, published in Nature Food, revealing that not just the quantity—but the diversity—of flavonoids in your diet can play a critical role in how long and how well you live. Using data from over 125,000 adults in the UK Biobank initiative, this study found that higher, more diverse flavonoid intake was linked to improved heart, immune, blood sugar, and cognitive health outcomes—and even reduced mortality rates. Carl reviews what this means for your daily nutrition, how to make smarter choices when selecting foods and supplements, and how NatureCity's approach supports this science-backed strategy for healthy aging. What You’ll Learn in This Episode:
Learn more about the TrueBerry7 formula and its scientifically supported ingredients: Subscribe to the channel for future episodes and actionable health tips. | |||
| The Hidden Hero Behind Your Supplements with Lauren Samot of Vitaquest | 08 juil. 2025 | 00:33:34 | |
In Tip #2 for supplement shopping, Carl Pradelli, co-founder and CEO of NatureCity, is joined by Lauren Samot, Commercial Innovation Leader at Vitaquest International to discuss the importance of knowing the actual manufacturer of the supplements you’re taking. The supplement brand is usually not the manufacturer because making supplement products is a highly specialized (and regulated) activity requiring many layers of expertise to deliver quality and safe products you can trust. What You'll Learn:
Behind the Scenes of Supplement Safety While most consumers focus on the supplement brand, it's the manufacturer who often plays a pivotal role in determining product quality. In this episode, Lauren and Carl pull back the curtain on the manufacturing world—from rigorous testing protocols and audits to third-party certifications and in-house labs. Lauren breaks down why it's vital to know where and how your supplements are made, emphasizing transparency and trust. You'll learn about the manufacturing tiers that separate premium producers like Vitaquest from less capable (and often questionable) operations, and why third-party testing alone isn't enough. Carl and Lauren discuss real examples of how early detection in quality labs prevents low quality and potentially harmful products from reaching your home. Plus, they reveal why branded, scientifically studied ingredients are your best bet for effectiveness and safety. Like what you heard? Subscribe on YouTube, Spotify, or Apple Podcasts. Leave a review to help others discover smarter supplement shopping tips! Links & Resources:Website: https://naturecity.com Email: support@naturecity.com Instagram: https://www.instagram.com/naturecitysupplements/ ===== ABOUT NATURECITY ===== NatureCity is dedicated to helping people live healthier, longer lives through transparency, education, and premium supplements. Founded over 20 years ago, we make products we personally take and are proud to recommend to our loved ones. Learn more at https://naturecity.com. | |||
| This Marine Collagen Breakthrough Works at Just 500mg | 24 juin 2025 | 00:51:20 | |
In this eye-opening episode, Carl Pradelli, co-founder of NatureCity, dives into the benefits, science, and sourcing of Cartidyss, a marine collagen breakthrough sourced from upcycled wild fish cartilage. Special guest Jocelyn Bérubé, EVP of Scientific Affairs at innoVactiv, unpacks why this clean, sustainable, and research backed collagen stands out from the crowd—offering powerful skin, hair and nail benefits at just 500mg per day. What You’ll Learn:
This is more than just another supplement chat—it’s a masterclass in how to choose a collagen supplement that really works for skin and joint health. Whether you’re in your 30s, 60s or older, this episode provides actionable insights on choosing the best collagen product. Subscribe for more inside wellness insights! Loved this episode? Subscribe and leave us a review on Apple Podcasts or Spotify! Find out more about TrueNuGrow+, featuring Cartidyss: https://naturecity.com | |||
| The Truth About Lutein: Vision, Brain Power & Its Essential Partner | 17 juin 2025 | 00:19:13 | |
Think lutein is just for your eyes? Think again. In this deep-dive episode, Carl Pradelli, co-founder and CEO of NatureCity, unpacks everything you didn’t know about this essential carotenoid—and why your brain and eyes might be silently craving more of it. Plus, it’s not a solo performer. To get the most from supplements with lutein, you need two other nutrients from the same antioxidant family. Find out the best natural source of these nutrients for supplements, misconceptions about food options with these nutrients, and what the science found about supplementing with lutein and its essential nutrient partners. What You’ll Discover:
Lutein is a powerhouse antioxidant often associated with eye health, but this episode reveals it also plays a crucial role in cognitive function. Carl breaks down why it’s so difficult to get enough lutein, zeaxanthin, and meso-zeaxanthin from food — especially in today’s processed food world — and how the USDA’s early data might still be leading to confusion in your nutrition choices. You’ll learn how lutein and its partner nutrients can help shield your eyes from blue light damage caused by screens, supports macular pigment density, and may even boost memory and stress resilience. Carl explains why foods thought to provide lutein AND the zeaxanthins actually don’t, and some better diet options for these nutrients (which are hard to get from diet alone). The episode also highlights Lutemax 2020, a science backed supplement ingredient that delivers all three essential carotenoids from a single marigold flower source — and why consistent intake may be your best strategy for long-term vision and brain support. Liked this episode? Subscribe to our YouTube channel and leave a review on Apple Podcasts or Spotify! https://www.youtube.com/@naturecitysupplements 🛒 Shop TrueVision with Lutemax 2020 & Affron Eye Saffron Extract: https://naturecity.com | |||
| Tip #1 for Choosing Quality Supplements: Branded Ingredients over Generics | 06 juin 2025 | 00:09:01 | |
Do you find shopping for supplements hard or frustrating? Worried you’re going to choose the wrong one or it’s not going to help you? Or worse – you’ll be wasting your money? In this episode of the NatureCity Podcast, CEO Carl Pradelli kicks off a new series on how to choose high quality supplements and avoid low-quality or fraudulent supplements. Tip #1: Choose branded ingredients over generic supplement ingredients. Carl breaks down what branded ingredients are, why they matter, and how they help ensure potency, purity, and protection from fraud. You'll also hear why all branded ingredients are not the same (or automatically good to take) and find out the standards companies like NatureCity use to ensure its customers are getting the very best in every capsule or scoop of powder.
👉 Learn more at https://www.naturecity.com 🎧 Subscribe on Spotify and Apple Podcasts 📺 Subscribe for more tips on supplement quality | |||
| Avoid Fake Aloe Vera! 5 Tips for Picking a Supplement that Actually Works | 02 juin 2025 | 00:09:25 | |
In this episode of the NatureCity Podcast, host Carl Pradelli, CEO and co-founder of NatureCity, breaks down his 5 essential tips to help you spot premium Aloe vera supplements and steer clear of products lacking potency or containing outright fake or adulterated Aloe. You’ll hear why USDA organic certification is especially important for Aloe vera, and the importance of choosing Aloe vera made with freeze-drying methods to preserve the Aloe vera “nutrient orchestra” and maximize benefits. Plus, the best way to ensure your Aloe vera isn’t really maltodextrin or cut with starch. If you're using Aloe vera for gut health, heart and metabolic health, joint health or to improve the appearance of your skin — this one's for you! 👉 Subscribe for weekly supplement tips! 👉 Leave a review on your favorite streaming platform. Check out the featured products: | |||
| Top 3 Gut Health Benefits of Aloe Vera | 23 mai 2025 | 00:08:00 | |
Discover how aloe vera supports gut health—from soothing your stomach to helping enhance nutrient absorption. In this episode of the NatureCity Podcast, host Carl Pradelli breaks down the top 3 digestive and gut health benefits of Aloe vera – one of the most popular botanicals used in supplements. Find out how Aloe vera can help balance stomach acid, improves nutrient absorption, and supports prebiotic activity and intestinal health to help support your digestive health. Carl also shares research-backed insights and reveals why certain Aloe vera supplements may not work – and gives a sneak peek into what to look for in a quality aloe supplement. Perfect for health-conscious listeners eager to optimize their digestion and gut health naturally. 👉 Subscribe to our YouTube channel for more natural health tips: https://www.youtube.com/@naturecitysupplements ⭐ Love the show? Leave us a review on Apple Podcasts or follow us on Spotify! Links: Check out True Aloe: https://www.naturecity.com/products/truealoe-organic-aloe-vera Check out AloeCran: https://www.naturecity.com/products/aloe-cran | |||
| Taking Regular Vitamin E? This Upgrade is Better | 16 mai 2025 | 00:08:44 | |
In this episode, Carl Pradelli, CEO and Co-founder of NatureCity, discusses some little-known facts about vitamin E. For starters, vitamin E is not a single substance, there are eight compounds that make up the vitamin E family – and science is showing the form that makes up most of our vitamin E intake (and used in most supplements) may be much less powerful and beneficial than some of the others. Carl also reveals why you’re shortchanging your health if you take synthetic vitamin E – and how to tell if your supplement is made with synthetic vitamin E. You’ll also hear about some of the latest research discoveries with the combination known as “Super Vitamin E.” This combines the five most potent forms of vitamin E, and research indicates it may offer valuable health benefits not seen with just the “regular” vitamin E (which is called alpha- tocopherol), Carl summarizes some of these findings for the brain, liver and cardiovascular system – and tells you where to find the Super Vitamin E! What You’ll Learn in This Episode ✅ Why synthetic Vitamin E supplements fall short ✅ The simple label trick to spot natural vs. synthetic Vitamin E ✅ Why tocotrienols may be up to 60x more powerful than regular Vitamin E ✅ How Super Vitamin E supports brain function, cardiovascular health, and liver protection ✅ The #1 vitamin E supplement you should consider: TrueE with EVNol SupraBio Learn more about TrueE: https://www.naturecity.com/ | |||
| Omega-3 Breakthroughs: New Research on Heart, Bone & Aging Health | 09 mai 2025 | 00:09:41 | |
Welcome to this episode of the NatureCity Podcast, where host and CEO Carl Pradelli dives deep into the latest scientific discoveries about Omega-3s and why these EPA and DHA fatty acids are so vital for your health. Backed by over 50 years of research, science continues to show the value of Omega-3s for cardiovascular health, bone strength, and longevity. In this episode, Carl reviews three new groundbreaking studies on the EPA and DHA Omega-3s, covering how they may keep circulating vesicles in a heathy range (excess amounts can impede blood flow and lead to blood clots), support bone health (especially in postmenopausal women), and slow biological aging by positively impacting PhenoAge scores. You’ll also learn what to look for in a high-quality fish oil supplement, including potency, purity, sustainability, and absorption. Carl explains why NatureCity’s TrueOmega-3supplement meets all these criteria and more—offering a highly bioavailable source of Omega-3s you can trust. What You’ll Learn from This Episode: ✅ The latest study from the British Journal of Nutrition finds that fish oil supplements may reduce harmful levels of circulating vesicles that impact heart health. ✅ Research from the journal Frontiers in Nutrition shows Omega-3 intake is linked to better bone health bones, especially in adults under 60. ✅ New findings reveal that Omega-3s can slow biological aging by improving blood markers that calculate your PhenoAge. ✅ Why EPA might be more important than DHA for circulating vesicle control—but both are essential for good health. ✅ How NASA’s astronaut bone loss research helped kickstart Omega-3 bone health studies. ✅ What makes a premium fish oil supplement: potency (EPA/DHA content), purity, sustainability, and bioavailability. 👉 If you're serious about optimizing your heart, bone, and aging health with Omega-3s, don’t miss this episode. 📌 Subscribe for more science-backed supplement education every week. | |||
| enXtra Thai ginger: Alertness, Energy & Focus Without Caffeine Crash | 28 avr. 2025 | 00:09:11 | |
Looking for a natural way to boost alertness and sustain mental energy throughout the day without relying on caffeine? We are too! In this special 100th episode of the NatureCity Podcast, co-founder and CEO Carl Pradelli takes you behind the science and findings with enXtra—a cutting-edge plant-based ingredient from Thai ginger, which is featured in the new TrueMind supplement. This innovation is timely because increasing mental energy for better cognitive performance topped the charts in a recent survey of consumer health goals. If you're struggling with mental fatigue, lack of focus, making too many mistakes or afternoon crashes, this episode will show you how to level up your productivity with the powerful enXtra plant extract – without resorting to more caffeine. Carl breaks down the research behind enXtra, including how it stacked up in a head-to-head study versus caffeine, and shares how this caffeine-free focus supplement can improve alertness, attention, calmness, and accuracy for at least 5 hours — without the jitters or crashes. What You’ll Learn in This Episode: ✅ What enXtra (Alpinia galanga / Thai ginger) is and how it works ✅ How enXtra compared to caffeine in head-to-head scientific study ✅ Why TrueMind can help you stay energized and focused for 5+ hours ✅ How enXtra supports dopamine activity—your brain’s motivation molecule ✅ Personal User experience: What were the benefits? ✅ How enXtra can improve accuracy and mental clarity within 30 minutes ✅ Avoiding the caffeine crash ✅ How Carl uses enXtra + caffeine strategically for peak focus ✅ Research found enXtra doesn’t affect sleep, blood pressure, or heart rate—even at double the dose ✅ What makes TrueMind ideal for busy professionals, and adults of all ages TrueMind is now available at https://naturecity.com Questions? Contact us anytime. And don’t forget to subscribe and follow us on Apple Podcasts or Spotify to stay up-to-date on future episodes! | |||