Life Sciences 360 – Détails, épisodes et analyse

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Life Sciences 360

Harsh Thakkar

Sciences

Fréquence : 1 épisode/11j. Total Éps: 86

Life Sciences 360 is an interview show that educates anyone on challenges, trends, and insights in the life-sciences industry. Hosted by Harsh Thakkar, a life-sciences industry veteran and CEO and co-founder of Qualtivate, the show features subject-matter experts, business leaders, and key life-science partners contributing to bringing new therapies to patients worldwide. Harsh is passionate about advancements in life sciences and tech and is always eager to learn from his guests— making the show both informative and useful.

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Données mises à jour le 04/07/2026

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https://sleek.bio/etienne
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Why Every Medical Affairs Team Needs Their Own AI Agent in 2025

Saison 4 · Épisode 86

mercredi 6 août 2025 • Durée 48:31

Medical misinformation, life sciences burnout, and AI-powered content creation collide in this episode with Dr. Ome Ogbru, founder & CEO of AINGENS and creator of MACg (Medical Affairs Content Generator).

Learn how AI in biotech is tackling the complexities of medical affairs—from literature review and content automation to compliance and regulatory writing.

⚡️ WHAT YOU’LL LEARN:

- Why medical affairs and regulatory teams can’t rely on ChatGPT alone.

- How MACg integrates real‑time PubMed search, citation generation, and secured collaboration to streamline scientific writing

- Why MACg users report up to 50 % faster writing and 50–70 % faster medical-legal review.

- Why AI platforms like MACg must be purpose-built for life sciences (GDPR & SOC 2 compliant).

- What is “human-in-the-loop” AI workflow—and how it balances automation and review to maintain accuracy and trust.

- Real-world use cases: scientific summaries, medical info letters and more.

🎙️ Guest: Ome Ogbru | Founder and President of AINGENS
🔗 Connect with Ome: LinkedIn

For transcripts, check out the podcast website - www.lifesciencespod.com

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VC Money Tight? Here’s How Startups Still Land Top Talent (2025)

Saison 4 · Épisode 85

jeudi 17 juillet 2025 • Durée 46:37

What happens when 3,500 staffers lose their jobs due to FDA layoffs, venture capital (VC) term sheets shrink, and AI drug-discovery startups raise $600 million rounds?

Executive recruiter William Holodnak (ex-Fidelity, global biotech headhunter) breaks down 2025’s wild hiring market—and how founders can still build A-teams.

In this episode you’ll learn:

- Why the April-1 FDA layoffs could delay approvals—and open new career doors for ex-regulators.

- The three traits VCs demand in first-time biotech CEOs during a funding slump.

- How AI-driven platforms like Isomorphic Labs raised mega-rounds in a down market.

- Immunology’s surge and why oncology startups are pivoting.

- Board-level recruiting tactics that de-risk your Series B.

🎙️ Guest: William Holodnak | Founder and President of Occam Global
🔗 Connect with Bill: LinkedIn

📌 Chapters:
00:00 Intro
05:45 Cambridge—“the Florence of Biotech” origin story
08:20 FDA layoffs: threat or opportunity?
13:30 Biotech venture capital mood swings & funding checkpoints
18:00 What VCs really screen for in scientific founders
25:05 The “horses for courses” CEO model explained
33:00 Hot therapeutic areas: AI drug discovery, immunology, repurposing
38:30 Why boards need operators, not just investors
47:00 Career improvisation: William’s closing advice

For transcripts, check out the podcast website - www.lifesciencespod.com

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Why Most Healthcare Brands Fail (And How to Fix It)

Saison 3 · Épisode 84

mercredi 28 mai 2025 • Durée 50:33

Why Most Healthcare Brands Fail (And How to Fix It)

In this episode, Holley Miller, Founder and President of Grey Matter Marketing, reveals why most medtech and life sciences companies fail to connect with their audience—and how to fix that with brand clarity and strategic storytelling.

You’ll learn how marketing in regulated industries is evolving, why flashy tactics often fall flat, and how brand equity is built through consistency, credibility, and emotional connection. Holley also shares lessons from working with emerging startups and large enterprises, offering a strategy for aligning commercial goals with patient and provider trust.

🎙️ Guest: Holley Miller | Founder and President of Grey Matter Marketing
🔗 Connect with Holley: LinkedIn

📌 Chapters:
00:00 The Journey of Grey Matter: 19 Years in Life Science Marketing
02:45 Evolution of Marketing in Life Sciences
05:59 Category Design: Creating and Owning a Market
08:54 Understanding Problems: The Key to Category Creation
12:02 Building the Right Team for Success
14:57 Painkillers vs. Vitamins: Motivating Change in Healthcare
27:30 Life Sciences Market Domination Framework
34:27 The Four Pillars of Market Success
42:31 Market Domination Scorecard: Assessing Your Strategy
45:09 What Matters: The Impact of Your Work
48:39 Finding Your Superpower

Subscribe for more insights on the latest in Life Sciences!

For transcripts, check out the podcast website - www.lifesciencespod.com

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4.5 Billion Molecules, One Mission: Cure the ‘Undruggable’ Diseases

Saison 3 · Épisode 83

mercredi 14 mai 2025 • Durée 30:57

Solving the “Undruggable” Disease Problem with Goldilocks Molecules

In this episode, Christian Schafmeister, Founder and President of Third Law Molecular, reveals a new class of therapeutics designed to target what most consider “undruggable” diseases—conditions like Alzheimer’s, certain cancers, and rare genetic disorders.

Christian explains the science behind spiroligomers—modular, mid-sized molecules that act like molecular LEGOs, offering the perfect balance between small molecules and biologics. Learn how his team created a library of 4.5 billion molecules and what makes these structures uniquely suited to bind difficult protein targets, including disordered proteins and intracellular surfaces.

We also talk about the Goldilocks Zone of drug design, how Third Law’s chemistry was born out of academic and defense-backed research, and why the future of drug discovery may lie in designing therapeutics that are just right.

🎙️ Guest: Christian Schafmeister | Founder and President at ThirdLaw Molecular
🔗 Connect with Christian: LinkedIn
🔗 ThirdLaw Molecular Website
🔗 Spiroligomers Presentation

📌 Chapters:
00:00 Introduction to Undruggable Diseases
01:30 Discovering Spiroligomers: A New Class of Molecules
08:04 Challenges in Targeted Drug Discovery
09:31 Building a Library of Molecules
14:47 The Birth of Third Law Molecular
17:19 The Goldilocks Molecule Concept
19:56 Applications in Cancer and Other Diseases
21:24 Collaborations with Big Pharma
23:39 Handling Clinical Trials
27:20 Future Directions and Industry Insights

Subscribe for more insights on the latest in Life Sciences!

For transcripts, check out the podcast website - www.lifesciencespod.com

What Separates Life Science Startup Winners from Losers?

Saison 3 · Épisode 82

mercredi 30 avril 2025 • Durée 38:46

Why Startups Fail (Hint: It’s Not the Innovation)

In this episode, Carlo Odicino, CEO and Founder at One TEAM Partners, shares the real reasons why most early-stage life sciences companies struggle to survive—and it has nothing to do with bad science.

Learn the hidden pitfalls of scaling too fast, confusing innovation with execution, and chasing too many priorities at once. Carlo offers practical strategies for building focus, setting boundaries, and creating a people-first culture that actually scales. You’ll also learn why execution beats experimentation when commercial success is the goal—and how to stay aligned with investors without over-promising.

This conversation is packed with actionable advice for startup leaders, biotech founders, and anyone facing the complexities of early-stage growth.

🎙️ Guest: Carlo Odicino | CEO and Founder at One TEAM Partners
🔗 Connect with Carlo: LinkedIn
🔗 One Team Partners Website

📌 Chapters:
00:00 The Innovation-Execution Tension
07:30 Managing Investor Expectations
17:48 Establishing Core Values in Organizations
24:56 Work-Life Integration vs. Balance
35:11 The Role of Human Connection in Innovation

Subscribe for more insights on the latest in Life Sciences!

For transcripts, check out the podcast website - www.lifesciencespod.com

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Pandora's Box of Secrets EXPOSED in Drug Pricing Transparency!

Saison 3 · Épisode 81

mercredi 23 avril 2025 • Durée 30:15

The Hidden Math Behind Drug Pricing: Why Patients Pay More Than They Should

In this episode, Michael Grosberg, VP of Product Management at Model N, breaks down the complex drug pricing ecosystem—revealing how rebates, PBMs, and outdated pricing models shape what patients actually pay.

You’ll learn how Pharmacy Benefit Managers (PBMs) really operate, why list prices are misleading, and how pricing negotiations impact patient access. Michael also unpacks the mechanics behind patient assistance programs, the role of compounding and independent pharmacies, and how emerging technology can bring transparency and efficiency to a broken system.

Whether you’re in life sciences, healthcare tech, or just want to understand why your prescription costs what it does—this is a must-listen conversation.

🎙️ Guest: Michael Grosberg | VP of Product Management at Model N
🔗 Connect with Michael Grosberg: LinkedIn
🔗 Model N LinkedIn
🔗 Model N
🔗 Drug Channels Institute

📌 Chapters:
00:00 Introduction to Pharmaceutical Pricing Dynamics
03:00 The Role of PBMs in Drug Affordability
06:13 Challenges with GLP-1 Medications and Independent Pharmacies
09:01 Understanding Drug Pricing and Stakeholder Dynamics
11:55 The Impact of List Prices on Patient Costs
15:05 Innovative Approaches to Healthcare Pricing
18:01 Patient Assistance Programs and Their Implications
20:44 The Role of Technology in Pharmaceutical Pricing
23:54 The Need for Transparency in Drug Pricing
26:59 Resources for Further Learning on Drug Pricing

Subscribe for more insights on the latest in Life Sciences!

For transcripts, check out the podcast website -

A CCO’s Brutally Honest Advice if You Want to Succeed in Pharma Commercialization

Saison 3 · Épisode 80

mercredi 16 avril 2025 • Durée 31:45

Early Commercialization Strategies That Actually Work (Especially for Startups!) In this episode, John Harlow, Chief Commercial Officer at Melinta Therapeutics, shares real-world strategies for how lean pharma startups can win the commercialization game—without Big Pharma budgets.

Discover how small companies can pivot fast, creatively optimize distribution, and make strategic decisions without endless red tape. John breaks down the critical mindset shift from R&D to commercial readiness, how to build high-performing teams in resource-constrained environments, and why smaller organizations often out-execute the giants.

We also discuss how to prioritize spend, what leaders should know before leaving Big Pharma, and the overlooked advantages of smaller teams.

🎙️ Guest: John Harlow | CCO of Melinta Therapeutics
🔗 Connect with John Harlow: LinkedIn

📌 Chapters:
00:00 The Challenges of Small Pharma
02:31 Understanding Melinta Therapeutics
04:44 Resource Constraints in Small Companies
08:30 The Speed of Decision-Making in Startups
10:15 Building a Cross-Functional Team
11:34 The Benefits of Small Team Dynamics
16:51 Case Study: Distribution Strategy Pivot
19:52 Creative Problem Solving in Resource Constraints
23:40 Staying Updated in the Pharma Space
27:34 Trends in Biotech and Pharma Startups
29:49 Building vs. Buying in Pharma

Subscribe for more insights on Biotech and Pharma Startups!

For transcripts, check out the podcast website - www.lifesciencespod.com

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Digital Health Expert: THIS is the No.1 Roadblock to Healthcare AI Adoption

Saison 3 · Épisode 79

mercredi 2 avril 2025 • Durée 35:12

Healthcare AI adoption is transforming the way we address risk, confidentiality, and patient care. In this episode, RJ Kedziora, co-founder of Estenda Solutions talks about the practical steps to safely integrate AI in clinical workflows.

Learn how to manage data privacy, mitigate algorithmic bias, and keep a human in the loop to prevent misdiagnoses. Discover real-world strategies for using AI ethically, from ambient listening to second-opinion checks, and why it’s irresponsible not to harness AI’s potential.

The discussion also highlights how AI can enhance the roles of healthcare professionals, ultimately improving patient outcomes.

🎙️ Guest: Richard Kedziora | co-founder/COO of Estenda Solutions
🔗 Connect with Richard Kedziora: LinkedIn

📌 Chapters:
00:00 Introduction to AI in Healthcare
03:01 Understanding Risks in AI Implementation
06:02 Confidentiality and Data Protection
09:03 Ethics and Explainability in AI
11:52 Bias in AI and Its Implications
15:09 Mitigating Risks in AI Usage
17:51 The Role of Humans in AI Decision Making
21:04 AI Enhancing Healthcare Professionals' Roles
24:10 Future of AI in Healthcare
26:57 Final Thoughts and Resources

Subscribe for more insights on AI in Healthcare!

For transcripts, check out the podcast website - www.lifesciencespod.com

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Tired of Supply Chain Errors? Here’s the Fix: Drug Serialization for DSCSA Compliance

Saison 3 · Épisode 78

mercredi 26 mars 2025 • Durée 39:50

Drug serialization is at the heart of modern pharmaceutical supply chain security. In this episode Michael Rowe, Senior Director of DSCSA and Serialization Services at TwoLabs, talks about the critical role of drug serialization and DSCSA compliance in safeguarding the pharmaceutical supply chain.

Michael explains how unique serial numbers, standardized data, and digital traceability are revolutionizing how drugs are tracked from manufacturer to pharmacy.

Discover real-world challenges and innovative solutions that ensure product integrity, reduce counterfeiting, and enhance operational efficiency in the pharma industry.

Whether you're involved in manufacturing, distribution, or regulatory affairs, learn how embracing drug serialization and DSCSA compliance can transform your operations.

🎙️ Guest: Michael Rowe | Senior Director of DSCSA and Serialization Services at TwoLabs
🔗 Connect with Michael Rowe: LinkedIn
📲 Learn more about TwoLabs
More information on FDA and DSCSA

📌 Chapters:
00:00 Introduction to DSCSA and Its Importance
03:07 Understanding the Drug Supply Chain Security Act
05:54 The Role of Serialization in Drug Traceability
09:04 Impact of DSCSA on Different Stakeholders
11:54 Challenges in Compliance and Operational Changes
15:01 The Role of Technology in DSCSA Compliance
20:21 Blockchain Challenges and Opportunities
22:47 AI in Exception Handling
27:38 Client Approaches: From Strategy to Implementation
32:12 Real-World Compliance Success Stories
35:53 Consequences of Non-Compliance
38:29 Resources for DSCSA Compliance

Subscribe for more insights on Life Sciences!

Why Equitable Healthcare is the KEY to Better Health

Saison 3 · Épisode 77

mercredi 19 mars 2025 • Durée 22:03

Equitable healthcare is the key to bridging health gaps and creating better patient outcomes. In this episode, Amy West, Principal, Advisory Services at HitLab, share her insights on how technology, digital health, and data can reshape access to care—especially for underserved communities.

Learn how addressing social determinants, using remote patient monitoring, and integrating wearables can empower patients and reduce disparities.

From real-world examples to actionable insights, Amy shares a vision for a more inclusive and effective healthcare system. Whether you’re a clinician, policymaker, or simply curious about the future of medicine, discover how innovative tools and a patient-centric approach can pave the way for true health equity.

🎙️ Guest: Amy West | Principal, Advisory Services & Chair for the Women’s Health Tech Initiative at HITLAB
🔗 Connect with Amy West: LinkedIn

📲 Learn more about HITLAB

📌 Chapters:
00:00-Exploring Healthcare Accessibility

06:49-Understanding Social Determinants of Health

12:00-The Role of Technology in Healthcare

17:51-Barriers in Women's Health

20:06-Future Trends in Digital Health

Subscribe for more insights on healthcare!

For transcripts, check out the podcast website - www.lifesciencespod.com

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